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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs146125856
log Bayes Factor = 12.7409
Chromosome 15   position 50,784,990  (GRCh37) Explore rs146125856 on Ensembl!
Variant rs146125856 is part of Cluster X0323

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
E10 Insulin-dependent diabetes mellitus
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.030 0.970
E10-E14 Diabetes mellitus
0.000 0.093 0.907
E10.4 With neurological complications
0.000 0.097 0.903
E10.1 With ketoacidosis
0.000 0.116 0.884
E14 Unspecified diabetes mellitus
0.000 0.169 0.831
E11 Non-insulin-dependent diabetes mellitus
0.000 0.184 0.816
E10.2 With renal complications
0.000 0.203 0.797
E10.5 With peripheral circulatory complications
0.000 0.229 0.771
E11.4 With neurological complications
0.000 0.236 0.764
E11.5 With peripheral circulatory complications
0.000 0.269 0.731
E14.9 Without complications
0.000 0.274 0.726
E10.8 With unspecified complications
0.000 0.279 0.721
E10.7 With multiple complications
0.000 0.285 0.715
E10.6 With other specified complications
0.000 0.285 0.715
E10.0 With coma
0.000 0.285 0.715
E14.3 With ophthalmic complications
0.000 0.292 0.708
E11.1 With ketoacidosis
0.000 0.319 0.681
E11.3 With ophthalmic complications
0.000 0.341 0.659
E12 Malnutrition-related diabetes mellitus
0.000 0.350 0.650
E11.2 With renal complications
0.000 0.399 0.601
E13 Other specified diabetes mellitus
0.000 0.401 0.599
E14.8 With unspecified complications
0.000 0.404 0.595
E14.7 With multiple complications
0.000 0.404 0.595
E14.6 With other specified complications
0.000 0.404 0.595
E14.5 With peripheral circulatory complications
0.000 0.404 0.595
E14.4 With neurological complications
0.000 0.404 0.595
E14.2 Withrenal complications
0.000 0.404 0.595
E14.1 With ketoacidosis
0.000 0.404 0.595
E14.0 With coma
0.000 0.404 0.595
E11.8 With unspecified complications
0.000 0.413 0.586
E11.7 With multiple complications
0.000 0.415 0.585
K90 Intestinal malabsorption
0.000 0.462 0.538
E11.6 With other specified complications
0.000 0.504 0.496
E12.9 Without complications
0.000 0.534 0.466
E12.8 With unspecified complications
0.000 0.534 0.466
E12.7 With multiple complications
0.000 0.534 0.466
E12.6 With other specified complications
0.000 0.534 0.466
E12.5 With peripheral circulatory complications
0.000 0.534 0.466
E12.4 With neurological complications
0.000 0.534 0.466
E12.3 With ophthalmic complications
0.000 0.534 0.466
E12.2 With renal complications
0.000 0.534 0.466
E12.1 With ketoacidosis
0.000 0.534 0.466
E12.0 With coma
0.000 0.534 0.466
E13.8 With unspecified complications
0.000 0.570 0.429
E13.7 With multiple complications
0.000 0.570 0.429
E13.6 With other specified complications
0.000 0.570 0.429
E13.5 With peripheral circulatory complications
0.000 0.570 0.429
E13.4 With neurological complications
0.000 0.570 0.429
E13.3 With ophthalmic complications
0.000 0.570 0.429
E13.2 With renal complications
0.000 0.570 0.429
E13.1 With ketoacidosis
0.000 0.570 0.429
E13.0 With coma
0.000 0.570 0.429
K90.9 Intestinal malabsorption, unspecified
0.000 0.597 0.403
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.611 0.389
K90.8 Other intestinal malabsorption
0.000 0.614 0.386
K90.3 Pancreatic steatorrhoea
0.000 0.614 0.386
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.614 0.386
K90.1 Tropical sprue
0.000 0.614 0.386
E13.9 Without complications
0.000 0.621 0.378
E11.0 With coma
0.001 0.624 0.376
E20-E35 Disorders of other endocrine glands
0.000 0.641 0.359
E50-E64 Other nutritional deficiencies
0.000 0.663 0.337
E29 Testicular dysfunction
0.000 0.670 0.330
E27 Other disorders of adrenal gland
0.000 0.678 0.322
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.685 0.315
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.687 0.313
E29.1 Testicular hypofunction
0.000 0.690 0.310
E53 Deficiency of other B group vitamins
0.000 0.702 0.298
E27.1 Primary adrenocortical insufficiency
0.000 0.705 0.295
K90-K93 Other diseases of the digestive system
0.000 0.717 0.283
E55 Vitamin D deficiency
0.000 0.722 0.278
E53.8 Deficiency of other specified B group vitamins
0.000 0.725 0.275
E23 Hypofunction and other disorders of pituitary gland
0.000 0.725 0.275
E22 Hyperfunction of pituitary gland
0.000 0.728 0.272
E70-E90 Metabolic disorders
0.000 0.728 0.271
E28 Ovarian dysfunction
0.000 0.736 0.264
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.738 0.262
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.739 0.261
E16 Other disorders of pancreatic internal secretion
0.000 0.742 0.258
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.742 0.258
E32 Diseases of thymus
0.000 0.742 0.258
E31 Polyglandular dysfunction
0.000 0.742 0.258
E30 Disorders of puberty, not elsewhere classified
0.000 0.742 0.258
E25 Adrenogenital disorders
0.000 0.742 0.258
E20 Hypoparathyroidism
0.000 0.742 0.258
E34 Other endocrine disorders
0.000 0.744 0.256
K91.3 Postoperative intestinal obstruction
0.000 0.748 0.252
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.749 0.251
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.750 0.250
E24 Cushing's syndrome
0.000 0.756 0.243
E27.8 Other specified disorders of adrenal gland
0.000 0.757 0.243
E26 Hyperaldosteronism
0.000 0.758 0.242
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.758 0.241
E63 Other nutritional deficiencies
0.000 0.758 0.241
E56 Other vitamin deficiencies
0.000 0.758 0.241
E51 Thiamine deficiency
0.000 0.758 0.241
E50 Vitamin A deficiency
0.000 0.758 0.241
E60 Dietary zinc deficiency
0.000 0.758 0.241
E59 Dietary selenium deficiency
0.000 0.758 0.241
E58 Dietary calcium deficiency
0.000 0.758 0.241
E54 Ascorbic acid deficiency
0.000 0.758 0.241
E52 Niacin deficiency [pellagra]
0.000 0.758 0.241
E87.7 Fluid overload
0.000 0.760 0.240
E29.9 Testicular dysfunction, unspecified
0.000 0.763 0.237
E29.8 Other testicular dysfunction
0.000 0.763 0.237
E29.0 Testicular hyperfunction
0.000 0.763 0.237
E87.5 Hyperkalaemia
0.000 0.763 0.237
E55.9 Vitamin D deficiency, unspecified
0.000 0.764 0.236
E40-E46 Malnutrition
0.000 0.764 0.236
E27.5 Adrenomedullary hyperfunction
0.000 0.769 0.231
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.769 0.231
E27.2 Addisonian crisis
0.000 0.769 0.231
E27.0 Other adrenocortical overactivity
0.000 0.769 0.231
E83 Disorders of mineral metabolism
0.000 0.775 0.224
E15 Nondiabetic hypoglycaemic coma
0.000 0.775 0.224
E83.1 Disorders of iron metabolism
0.000 0.776 0.224
J45.9 Asthma, unspecified
0.000 0.776 0.224
E16.2 Hypoglycaemia, unspecified
0.000 0.777 0.223
E88 Other metabolic disorders
0.000 0.785 0.215
E53.1 Pyridoxine deficiency
0.000 0.786 0.214
E53.0 Riboflavin deficiency
0.000 0.786 0.214
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.789 0.211
E73 Lactose intolerance
0.000 0.789 0.211
E85 Amyloidosis
0.000 0.790 0.210
E23.2 Diabetes insipidus
0.000 0.792 0.208
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.794 0.206
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.797 0.203
E23.0 Hypopituitarism
0.000 0.797 0.203
E23.6 Other disorders of pituitary gland
0.000 0.799 0.201
E55.0 Rickets, active
0.000 0.800 0.200
E28.3 Primary ovarian failure
0.000 0.801 0.199
E23.7 Disorder of pituitary gland, unspecified
0.000 0.802 0.197
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.802 0.197
E23.1 Drug-induced hypopituitarism
0.000 0.802 0.197
E22.0 Acromegaly and pituitary gigantism
0.000 0.803 0.197
E53.9 Vitamin B deficiency, unspecified
0.000 0.803 0.197
E22.1 Hyperprolactinaemia
0.000 0.804 0.196
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.805 0.195
E22.8 Other hyperfunction of pituitary gland
0.000 0.805 0.195
E84 Cystic fibrosis
0.000 0.805 0.195
E79 Disorders of purine and pyrimidine metabolism
0.000 0.805 0.195
E77 Disorders of glycoprotein metabolism
0.000 0.805 0.195
E76 Disorders of glycosaminoglycan metabolism
0.000 0.805 0.195
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.805 0.195
E72 Other disorders of amino-acid metabolism
0.000 0.805 0.195
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.805 0.195
E70 Disorders of aromatic amino-acid metabolism
0.000 0.805 0.195
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.805 0.195
E87.0 Hyperosmolality and hypernatraemia
0.000 0.807 0.193
E28.9 Ovarian dysfunction, unspecified
0.000 0.811 0.189
E28.8 Other ovarian dysfunction
0.000 0.811 0.189
E28.1 Androgen excess
0.000 0.811 0.189
E28.0 Oestrogen excess
0.000 0.811 0.189
E87.4 Mixed disorder of acid-base balance
0.000 0.812 0.188
E27.9 Disorder of adrenal gland, unspecified
0.000 0.812 0.187
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.813 0.187
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.813 0.187
K91.5 Postcholecystectomy syndrome
0.000 0.813 0.187
E61 Deficiency of other nutrient elements
0.000 0.813 0.186
E28.2 Polycystic ovarian syndrome
0.000 0.815 0.185
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.815 0.185
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.815 0.185
E16.4 Abnormal secretion of gastrin
0.000 0.815 0.185
E16.3 Increased secretion of glucagon
0.000 0.815 0.185
E20.9 Hypoparathyroidism, unspecified
0.000 0.815 0.185
E20.8 Other hypoparathyroidism
0.000 0.815 0.185
E20.1 Pseudohypoparathyroidism
0.000 0.815 0.185
E20.0 Idiopathic hypoparathyroidism
0.000 0.815 0.185
E25.9 Adrenogenital disorder, unspecified
0.000 0.815 0.185
E25.8 Other adrenogenital disorders
0.000 0.815 0.185
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.815 0.185
E30.9 Disorder of puberty, unspecified
0.000 0.815 0.185
E30.8 Other disorders of puberty
0.000 0.815 0.185
E30.1 Precocious puberty
0.000 0.815 0.185
E30.0 Delayed puberty
0.000 0.815 0.185
E31.9 Polyglandular dysfunction, unspecified
0.000 0.815 0.185
E31.8 Other polyglandular dysfunction
0.000 0.815 0.185
E31.1 Polyglandular hyperfunction
0.000 0.815 0.185
E31.0 Autoimmune polyglandular failure
0.000 0.815 0.185
E32.9 Disease of thymus, unspecified
0.000 0.815 0.185
E32.8 Other diseases of thymus
0.000 0.815 0.185
E32.1 Abscess of thymus
0.000 0.815 0.185
E32.0 Persistent hyperplasia of thymus
0.000 0.815 0.185
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.815 0.185
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.815 0.185
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.815 0.185
E34.9 Endocrine disorder, unspecified
0.000 0.815 0.185
E34.5 Androgen resistance syndrome
0.000 0.816 0.183
E34.4 Constitutional tall stature
0.000 0.816 0.183
E34.3 Short stature, not elsewhere classified
0.000 0.816 0.183
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.816 0.183
E34.1 Other hypersecretion of intestinal hormones
0.000 0.816 0.183
E34.0 Carcinoid syndrome
0.000 0.816 0.183
E34.8 Other specified endocrine disorders
0.000 0.820 0.180
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.821 0.178
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.822 0.178
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.822 0.177
E74 Other disorders of carbohydrate metabolism
0.000 0.823 0.177
E24.8 Other Cushing's syndrome
0.000 0.825 0.175
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.825 0.175
E24.3 Ectopic ACTH syndrome
0.000 0.825 0.175
E24.2 Drug-induced Cushing's syndrome
0.000 0.825 0.175
E24.1 Nelson's syndrome
0.000 0.825 0.175
E24.0 Pituitary-dependent Cushing's disease
0.000 0.825 0.175
E26.9 Hyperaldosteronism, unspecified
0.000 0.826 0.174
E26.8 Other hyperaldosteronism
0.000 0.826 0.174
E26.1 Secondary hyperaldosteronism
0.000 0.826 0.174
E16.1 Other hypoglycaemia
0.000 0.826 0.173
E50.9 Vitamin A deficiency, unspecified
0.000 0.826 0.173
E50.8 Other manifestations of vitamin A deficiency
0.000 0.826 0.173
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.826 0.173
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.826 0.173
E50.5 Vitamin A deficiency with night blindness
0.000 0.826 0.173
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.826 0.173
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.826 0.173
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.826 0.173
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.826 0.173
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.826 0.173
E51.9 Thiamine deficiency, unspecified
0.000 0.826 0.173
E51.8 Other manifestations of thiamine deficiency
0.000 0.826 0.173
E51.2 Wernicke's encephalopathy
0.000 0.826 0.173
E51.1 Beriberi
0.000 0.826 0.173
E56.9 Vitamin deficiency, unspecified
0.000 0.826 0.173
E56.8 Deficiency of other vitamins
0.000 0.826 0.173
E56.1 Deficiency of vitamin K
0.000 0.826 0.173
E56.0 Deficiency of vitamin E
0.000 0.826 0.173
E63.9 Nutritional deficiency, unspecified
0.000 0.826 0.173
E63.8 Other specified nutritional deficiencies
0.000 0.826 0.173
E63.1 Imbalance of constituents of food intake
0.000 0.826 0.173
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.826 0.173
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.826 0.173
E64.8 Sequelae of other nutritional deficiencies
0.000 0.826 0.173
E64.3 Sequelae of rickets
0.000 0.826 0.173
E64.2 Sequelae of vitamin C deficiency
0.000 0.826 0.173
E64.1 Sequelae of vitamin A deficiency
0.000 0.826 0.173
E64.0 Sequelae of protein-energy malnutrition
0.000 0.826 0.173
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.828 0.171
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.830 0.169
E45 Retarded development following protein-energy malnutrition
0.000 0.830 0.169
E43 Unspecified severe protein-energy malnutrition
0.000 0.830 0.169
E42 Marasmic kwashiorkor
0.000 0.830 0.169
E41 Nutritional marasmus
0.000 0.830 0.169
E40 Kwashiorkor
0.000 0.830 0.169
E87.3 Alkalosis
0.000 0.831 0.169
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.831 0.169
E73.9 Lactose intolerance, unspecified
0.000 0.833 0.167
K91.1 Postgastric surgery syndromes
0.000 0.833 0.167
J45 Asthma
0.000 0.835 0.165
E85.4 Organ-limited amyloidosis
0.000 0.837 0.162
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.839 0.161
E83.8 Other disorders of mineral metabolism
0.000 0.839 0.161
E83.2 Disorders of zinc metabolism
0.000 0.839 0.161
E83.0 Disorders of copper metabolism
0.000 0.839 0.161
E24.9 Cushing's syndrome, unspecified
0.000 0.839 0.160
E87.2 Acidosis
0.000 0.840 0.160
E26.0 Primary hyperaldosteronism
0.000 0.842 0.158
E85.9 Amyloidosis, unspecified
0.000 0.845 0.155
E88.9 Metabolic disorder, unspecified
0.000 0.846 0.154
E88.8 Other specified metabolic disorders
0.000 0.846 0.154
E88.3 Tumour lysis syndrome
0.000 0.846 0.154
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.846 0.154
K91.4 Colostomy and enterostomy malfunction
0.000 0.848 0.152
J45.0 Predominantly allergic asthma
0.000 0.849 0.151
E73.8 Other lactose intolerance
0.000 0.849 0.151
E73.1 Secondary lactase deficiency
0.000 0.849 0.151
E73.0 Congenital lactase deficiency
0.000 0.849 0.151
E85.8 Other amyloidosis
0.000 0.849 0.151
E85.3 Secondary systemic amyloidosis
0.000 0.849 0.151
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.849 0.151
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.849 0.151
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.849 0.151
E88.2 Lipomatosis, not elsewhere classified
0.000 0.851 0.148
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.854 0.146
K93.1 Megacolon in Chagas' disease
0.000 0.854 0.146
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.854 0.146
E65-E68 Obesity and other hyperalimentation
0.000 0.860 0.140
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.860 0.140
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.860 0.140
E70.3 Albinism
0.000 0.860 0.140
E70.2 Disorders of tyrosine metabolism
0.000 0.860 0.140
E70.1 Other hyperphenylalaninaemias
0.000 0.860 0.140
E70.0 Classical phenylketonuria
0.000 0.860 0.140
E71.3 Disorders of fatty-acid metabolism
0.000 0.860 0.140
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.860 0.140
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.860 0.140
E71.0 Maple-syrup-urine disease
0.000 0.860 0.140
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.860 0.140
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.860 0.140
E72.5 Disorders of glycine metabolism
0.000 0.860 0.140
E72.4 Disorders of ornithine metabolism
0.000 0.860 0.140
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.860 0.140
E72.2 Disorders of urea cycle metabolism
0.000 0.860 0.140
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.860 0.140
E72.0 Disorders of amino-acid transport
0.000 0.860 0.140
E75.6 Lipid storage disorder, unspecified
0.000 0.860 0.140
E75.5 Other lipid storage disorders
0.000 0.860 0.140
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.860 0.140
E75.3 Sphingolipidosis, unspecified
0.000 0.860 0.140
E75.2 Other sphingolipidosis
0.000 0.860 0.140
E75.1 Other gangliosidosis
0.000 0.860 0.140
E75.0 GM2 gangliosidosis
0.000 0.860 0.140
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.860 0.140
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.860 0.140
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.860 0.140
E76.2 Other mucopolysaccharidoses
0.000 0.860 0.140
E76.1 Mucopolysaccharidosis, type II
0.000 0.860 0.140
E76.0 Mucopolysaccharidosis, type I
0.000 0.860 0.140
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.860 0.140
E77.8 Other disorders of glycoprotein metabolism
0.000 0.860 0.140
E77.1 Defects in glycoprotein degradation
0.000 0.860 0.140
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.860 0.140
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.860 0.140
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.860 0.140
E79.1 Lesch-Nyhan syndrome
0.000 0.860 0.140
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.860 0.140
E84.9 Cystic fibrosis, unspecified
0.000 0.860 0.140
E84.8 Cystic fibrosis with other manifestations
0.000 0.860 0.140
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.860 0.140
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.860 0.140
E61.9 Deficiency of nutrient element, unspecified
0.000 0.866 0.134
E61.8 Deficiency of other specified nutrient elements
0.000 0.866 0.134
E61.7 Deficiency of multiple nutrient elements
0.000 0.866 0.134
E61.6 Vanadium deficiency
0.000 0.866 0.134
E61.5 Molybdenum deficiency
0.000 0.866 0.134
E61.4 Chromium deficiency
0.000 0.866 0.134
E61.3 Manganese deficiency
0.000 0.866 0.134
E61.0 Copper deficiency
0.000 0.866 0.134
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.001 0.866 0.134
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.873 0.127
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.873 0.127
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.873 0.127
E74.2 Disorders of galactose metabolism
0.000 0.873 0.127
E74.1 Disorders of fructose metabolism
0.000 0.873 0.127
E74.0 Glycogen storage disease
0.000 0.873 0.127
E46 Unspecified protein-energy malnutrition
0.001 0.873 0.126
E83.3 Disorders of phosphorus metabolism
0.000 0.874 0.125
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.877 0.123
E80.6 Other disorders of bilirubin metabolism
0.000 0.877 0.123
E80.5 Crigler-Najjar syndrome
0.000 0.877 0.123
E80.3 Defects of catalase and peroxydase
0.000 0.877 0.123
E80.2 Other porphyria
0.000 0.877 0.123
E80.1 Porphyria cutanea tarda
0.000 0.877 0.123
E80.0 Hereditary erythropoietic porphyria
0.000 0.877 0.123
E61.2 Magnesium deficiency
0.000 0.878 0.122
E44.1 Mild protein-energy malnutrition
0.000 0.878 0.121
E44.0 Moderate protein-energy malnutrition
0.000 0.878 0.121
J45.8 Mixed asthma
0.000 0.881 0.118
J45.1 Nonallergic asthma
0.000 0.881 0.118
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.891 0.109
R31 Unspecified haematuria
0.105 0.895 0.000
K92 Other diseases of digestive system
0.000 0.897 0.103
E67 Other hyperalimentation
0.000 0.899 0.101
E68 Sequelae of hyperalimentation
0.000 0.899 0.101
E80.4 Gilbert's syndrome
0.000 0.900 0.100
E61.1 Iron deficiency
0.000 0.901 0.099
E86 Volume depletion
0.000 0.903 0.097
E21.5 Disorder of parathyroid gland, unspecified
0.001 0.904 0.096
E21.4 Other specified disorders of parathyroid gland
0.001 0.904 0.096
E21.2 Other hyperparathyroidism
0.001 0.904 0.096
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.093 0.907 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.001 0.909 0.090
E83.4 Disorders of magnesium metabolism
0.000 0.914 0.086
E21.3 Hyperparathyroidism, unspecified
0.000 0.915 0.085
K92.2 Gastro-intestinal haemorrhage, unspecified
0.000 0.918 0.082
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.923 0.077
E65 Localised adiposity
0.001 0.925 0.075
M06.9 Rheumatoid arthritis, unspecified
0.000 0.925 0.075
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.927 0.073
E67.8 Other specified hyperalimentation
0.000 0.927 0.072
E67.3 Hypervitaminosis D
0.000 0.927 0.072
E67.2 Megavitamin-B6 syndrome
0.000 0.927 0.072
E67.1 Hypercarotenaemia
0.000 0.927 0.072
E67.0 Hypervitaminosis A
0.000 0.927 0.072
K92.1 Melaena
0.000 0.930 0.070
K92.8 Other specified diseases of digestive system
0.000 0.932 0.067
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.067 0.933 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.935 0.065
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.935 0.065
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.935 0.065
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.937 0.063
E03.9 Hypothyroidism, unspecified
0.063 0.937 0.000
E00-E07 Disorders of thyroid gland
0.027 0.939 0.034
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.940 0.060
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.941 0.059
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.943 0.057
D50 Iron deficiency anaemia
0.000 0.943 0.057
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.944 0.056
D50.8 Other iron deficiency anaemias
0.000 0.944 0.056
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.944 0.055
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.944 0.055
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.944 0.055
E89.5 Postprocedural testicular hypofunction
0.000 0.944 0.055
E89.1 Postprocedural hypoinsulinaemia
0.000 0.944 0.055
E03 Other hypothyroidism
0.038 0.944 0.018
D51 Vitamin B12 deficiency anaemia
0.000 0.944 0.056
D50.9 Iron deficiency anaemia, unspecified
0.000 0.944 0.056
D50-D53 Nutritional anaemias
0.000 0.946 0.054
C82.3 Follicular lymphoma grade IIIa
0.054 0.946 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.946 0.054
C82.0 Small cleaved cell, follicular
0.053 0.947 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.948 0.052
K92.9 Disease of digestive system, unspecified
0.000 0.949 0.051
C82.1 Mixed small cleaved and large cell, follicular
0.050 0.950 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.950 0.050
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.050 0.950 0.000
C82.6 Cutaneous follicle centre lymphoma
0.048 0.952 0.000
C82.5 Diffuse follicle centre lymphoma
0.048 0.952 0.000
C82.4 Follicular lymphoma grade IIIb
0.048 0.952 0.000
C82.2 Large cell, follicular
0.048 0.952 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.001 0.952 0.047
M06 Other rheumatoid arthritis
0.000 0.953 0.047
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.953 0.047
E89.4 Postprocedural ovarian failure
0.000 0.953 0.046
E89.2 Postprocedural hypoparathyroidism
0.000 0.954 0.046
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.020 0.956 0.025
E00 Congenital iodine-deficiency syndrome
0.020 0.956 0.025
E02 Subclinical iodine-deficiency hypothyroidism
0.022 0.957 0.021
E07 Other disorders of thyroid
0.023 0.958 0.020
N80.0 Endometriosis of uterus
0.000 0.959 0.041
D50.1 Sideropenic dysphagia
0.000 0.959 0.041
E03.5 Myxoedema coma
0.027 0.960 0.013
E03.4 Atrophy of thyroid (acquired)
0.027 0.960 0.013
E03.3 Postinfectious hypothyroidism
0.027 0.960 0.013
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.027 0.960 0.013
E03.1 Congenital hypothyroidism without goitre
0.027 0.960 0.013
E03.0 Congenital hypothyroidism with diffuse goitre
0.027 0.960 0.013
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.960 0.040
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.960 0.040
D51.2 Transcobalamin II deficiency
0.000 0.960 0.040
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.960 0.040
C67.9 Bladder, unspecified
0.000 0.960 0.040
D53 Other nutritional anaemias
0.000 0.960 0.040
N80.1 Endometriosis of ovary
0.000 0.960 0.040
E06 Thyroiditis
0.021 0.961 0.018
N80 Endometriosis
0.000 0.961 0.039
E78.2 Mixed hyperlipidaemia
0.001 0.962 0.038
M05-M14 Inflammatory polyarthropathies
0.000 0.963 0.037
N80.3 Endometriosis of pelvic peritoneum
0.000 0.963 0.037
E05 Thyrotoxicosis [hyperthyroidism]
0.016 0.964 0.020
M07 Psoriatic and enteropathic arthropathies
0.000 0.964 0.036
M07.3 Other psoriatic arthropathies
0.000 0.964 0.036
E78.1 Pure hyperglyceridaemia
0.001 0.964 0.035
E03.8 Other specified hypothyroidism
0.021 0.964 0.014
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.964 0.036
M06.3 Rheumatoid nodule
0.000 0.965 0.035
E78.6 Lipoprotein deficiency
0.001 0.965 0.034
E78.3 Hyperchylomicronaemia
0.001 0.965 0.034
D52 Folate deficiency anaemia
0.000 0.966 0.034
M06.8 Other specified rheumatoid arthritis
0.000 0.966 0.034
M06.2 Rheumatoid bursitis
0.000 0.966 0.034
M06.1 Adult-onset Still's disease
0.000 0.966 0.034
E78.9 Disorder of lipoprotein metabolism, unspecified
0.001 0.967 0.033
M05 Seropositive rheumatoid arthritis
0.000 0.967 0.033
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.014 0.968 0.018
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.014 0.968 0.018
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.014 0.968 0.018
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.014 0.968 0.018
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.014 0.968 0.018
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.014 0.968 0.018
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.014 0.968 0.018
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.014 0.968 0.018
C67 Malignant neoplasm of bladder
0.000 0.968 0.032
K92.0 Haematemesis
0.000 0.968 0.032
E66 Obesity
0.000 0.968 0.031
E78.8 Other disorders of lipoprotein metabolism
0.001 0.969 0.031
E78.4 Other hyperlipidaemia
0.001 0.969 0.030
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.969 0.031
E07.1 Dyshormogenetic goitre
0.016 0.969 0.014
E07.0 Hypersecretion of calcitonin
0.016 0.969 0.014
D53.9 Nutritional anaemia, unspecified
0.000 0.970 0.030
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.971 0.029
N80.9 Endometriosis, unspecified
0.000 0.971 0.029
E07.8 Other specified disorders of thyroid
0.014 0.971 0.016
J40-J47 Chronic lower respiratory diseases
0.002 0.971 0.027
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.971 0.029
D53.8 Other specified nutritional anaemias
0.000 0.971 0.029
D53.2 Scorbutic anaemia
0.000 0.971 0.029
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.971 0.029
D53.0 Protein deficiency anaemia
0.000 0.971 0.029
M06.4 Inflammatory polyarthropathy
0.000 0.971 0.029
N80.5 Endometriosis of intestine
0.000 0.971 0.028
E06.5 Other chronic thyroiditis
0.016 0.972 0.013
E06.4 Drug-induced thyroiditis
0.016 0.972 0.013
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.016 0.972 0.013
E06.1 Subacute thyroiditis
0.016 0.972 0.013
E06.0 Acute thyroiditis
0.016 0.972 0.013
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.972 0.028
M14 Arthropathies in other diseases classified elsewhere
0.000 0.972 0.028
N80.6 Endometriosis in cutaneous scar
0.000 0.972 0.028
N80.4 Endometriosis of rectovaginal septum and vagina
0.000 0.972 0.028
E83.5 Disorders of calcium metabolism
0.001 0.972 0.028
M06.0 Seronegative rheumatoid arthritis
0.000 0.972 0.028
E06.9 Thyroiditis, unspecified
0.017 0.972 0.011
M12 Other specific arthropathies
0.000 0.973 0.027
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.973 0.027
M08 Juvenile arthritis
0.000 0.973 0.027
E21.0 Primary hyperparathyroidism
0.001 0.973 0.025

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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