TreeWAS – Variant ID: rs1475545

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z98.1 Arthrodesis status	0.025	0.975	0.000
C22.0 Liver cell carcinoma	0.022	0.978	0.000
Z90.8 Acquired absence of other organs	0.019	0.981	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.984	0.016
C22.9 Liver, unspecified	0.015	0.985	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.015	0.985	0.000
H65 Nonsuppurative otitis media	0.000	0.985	0.015
H65.3 Chronic mucoid otitis media	0.000	0.986	0.014
L29.9 Pruritus, unspecified	0.000	0.987	0.013
O14.9 Preeclampsia, unspecified	0.013	0.987	0.000
H65.0 Acute serous otitis media	0.000	0.988	0.012
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.012	0.988	0.000
O14.0 Moderate preeclampsia	0.012	0.988	0.000
C22.7 Other specified carcinomas of liver	0.011	0.989	0.000
C22.4 Other sarcomas of liver	0.011	0.989	0.000
C22.3 Angiosarcoma of liver	0.011	0.989	0.000
C22.2 Hepatoblastoma	0.011	0.989	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.989	0.011
H65.1 Other acute nonsuppurative otitis media	0.000	0.990	0.010
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.010	0.990	0.000
H65.2 Chronic serous otitis media	0.000	0.991	0.009
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.009	0.991	0.000
H65-H75 Diseases of middle ear and mastoid	0.000	0.991	0.009
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.009	0.991	0.000
O14.2 HELLP syndrome	0.009	0.991	0.000
H69 Other disorders of Eustachian tube	0.000	0.991	0.009
F31.0 Bipolar affective disorder, current episode hypomanic	0.009	0.991	0.000
F31 Bipolar affective disorder	0.009	0.991	0.000
C22.1 Intrahepatic bile duct carcinoma	0.008	0.992	0.000
C18.7 Sigmoid colon	0.000	0.992	0.008
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.008	0.992	0.000
H72 Perforation of tympanic membrane	0.000	0.992	0.008
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.008	0.992	0.000
F31.7 Bipolar affective disorder, currently in remission	0.008	0.992	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.992	0.008
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.008	0.992	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.007	0.993	0.000
H69.8 Other specified disorders of Eustachian tube	0.000	0.993	0.007
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.993	0.007
H72.8 Other perforations of tympanic membrane	0.000	0.993	0.007
H66 Suppurative and unspecified otitis media	0.000	0.993	0.007
O15 Eclampsia	0.007	0.993	0.000
H73 Other disorders of tympanic membrane	0.000	0.993	0.007
H71 Cholesteatoma of middle ear	0.000	0.993	0.007
H68 Eustachian salpingitis and obstruction	0.000	0.993	0.007
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.993	0.007
H67 Otitis media in diseases classified elsewhere	0.000	0.993	0.007
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
F31.8 Other bipolar affective disorders	0.007	0.993	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.993	0.007
H69.0 Patulous Eustachian tube	0.000	0.993	0.006
H72.2 Other marginal perforations of tympanic membrane	0.000	0.994	0.006
O14.1 Severe preeclampsia	0.006	0.994	0.000
F31.9 Bipolar affective disorder, unspecified	0.006	0.994	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.006	0.994	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.006	0.994	0.000
N85.4 Malposition of uterus	0.006	0.994	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.994	0.006
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.006	0.994	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.994	0.006
H72.1 Attic perforation of tympanic membrane	0.000	0.994	0.006
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.006	0.994	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.994	0.006
D84.9 Immunodeficiency, unspecified	0.000	0.994	0.006
J32.2 Chronic ethmoidal sinusitis	0.000	0.994	0.006
M21.4 Flat foot [pes planus] (acquired)	0.006	0.994	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.994	0.006
M21.6 Other acquired deformities of ankle and foot	0.005	0.994	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.994	0.005
H68.1 Obstruction of Eustachian tube	0.000	0.995	0.005
O15.9 Eclampsia, unspecified as to time period	0.005	0.995	0.000
O15.2 Eclampsia in the puerperium	0.005	0.995	0.000
O15.1 Eclampsia in labour	0.005	0.995	0.000
O15.0 Eclampsia in pregnancy	0.005	0.995	0.000
O16 Unspecified maternal hypertension	0.005	0.995	0.000
M21 Other acquired deformities of limbs	0.005	0.995	0.000
H73.0 Acute myringitis	0.000	0.995	0.005
H68.0 Eustachian salpingitis	0.000	0.995	0.005
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.995	0.005
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.995	0.005
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.995	0.005
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.995	0.005
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
F31.6 Bipolar affective disorder, current episode mixed	0.005	0.995	0.000
H73.1 Chronic myringitis	0.000	0.995	0.005
H66.9 Otitis media, unspecified	0.000	0.995	0.005
H66.4 Suppurative otitis media, unspecified	0.000	0.995	0.005
H70 Mastoiditis and related conditions	0.000	0.995	0.005
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.005	0.995	0.000
M21.3 Wrist or foot drop (acquired)	0.005	0.995	0.000
D84 Other immunodeficiencies	0.000	0.995	0.005
H66.0 Acute suppurative otitis media	0.000	0.995	0.005
M21.1 Varus deformity, not elsewhere classified	0.005	0.995	0.000
O12.2 Gestational oedema with proteinuria	0.005	0.995	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.005	0.995	0.000
M25.84 Other specified joint disorders (Hand)	0.005	0.995	0.000
G61.0 Guillain-Barre syndrome	0.005	0.995	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.005	0.995	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
H74 Other disorders of middle ear and mastoid	0.000	0.995	0.005
M21.9 Acquired deformity of limb, unspecified	0.005	0.995	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.995	0.005
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.004	0.995	0.000
E04.1 Non-toxic single thyroid nodule	0.005	0.995	0.000
Z50.0 Cardiac rehabilitation	0.005	0.995	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.004	0.996	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.004	0.996	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.996	0.004
K05.3 Chronic periodontitis	0.004	0.996	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.004	0.996	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.004	0.996	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.004	0.996	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.004	0.996	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.004	0.996	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.004	0.996	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.004	0.996	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.004	0.996	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.004	0.996	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.004	0.996	0.000
M21.7 Unequal limb length (acquired)	0.004	0.996	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.004	0.996	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.004	0.996	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.004	0.996	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.004	0.996	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.004	0.996	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.004	0.996	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.004	0.996	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.004	0.996	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.004	0.996	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.004	0.996	0.000
M21.8 Other specified acquired deformities of limbs	0.004	0.996	0.000
O12.1 Gestational proteinuria	0.004	0.996	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.996	0.004
D84.8 Other specified immunodeficiencies	0.000	0.996	0.004
D84.1 Defects in the complement system	0.000	0.996	0.004
D80-D89 Certain disorders involving the immune mechanism	0.000	0.996	0.004
H70.2 Petrositis	0.000	0.996	0.004
O12.0 Gestational oedema	0.004	0.996	0.000
H70.9 Mastoiditis, unspecified	0.000	0.996	0.004
D86 Sarcoidosis	0.000	0.996	0.004
M21.39 Wrist or foot drop (acquired)-Site unspec	0.004	0.996	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.004	0.996	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.004	0.996	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.004	0.996	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.004	0.996	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.004	0.996	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.004	0.996	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.004	0.996	0.000
S80.9 Superficial injury of lower leg, unspecified	0.000	0.996	0.004
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.996	0.004
H74.1 Adhesive middle ear disease	0.000	0.996	0.004
H74.0 Tympanosclerosis	0.000	0.996	0.004
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.004	0.996	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.004	0.996	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.004	0.996	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
H70.1 Chronic mastoiditis	0.000	0.996	0.003
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.996	0.004
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.004	0.996	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.004	0.996	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.004	0.996	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.004	0.996	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.004	0.996	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.004	0.996	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.004	0.996	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.004	0.996	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.996	0.004
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.004	0.996	0.000
K85.1 Biliary acute pancreatitis	0.004	0.996	0.000
C45.0 Mesothelioma of pleura	0.000	0.996	0.004
L29 Pruritus	0.000	0.996	0.004
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.003	0.996	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.003	0.996	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.003	0.996	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.003	0.996	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.003	0.996	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.003	0.996	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.003	0.996	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.003	0.996	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.996	0.004
D86.0 Sarcoidosis of lung	0.000	0.996	0.004
M21.76 Unequal limb length (acquired) (Lower leg)	0.003	0.996	0.000
K56.2 Volvulus	0.004	0.996	0.000
D83 Common variable immunodeficiency	0.000	0.996	0.003
H70.0 Acute mastoiditis	0.000	0.997	0.003
R44.1 Visual hallucinations	0.003	0.997	0.000
R44.0 Auditory hallucinations	0.003	0.997	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.003	0.997	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.997	0.003
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.997	0.003
M21.79 Unequal limb length (acquired) (Site unspecified)	0.003	0.997	0.000
M21.78 Unequal limb length (acquired)-Other	0.003	0.997	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.003	0.997	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.003	0.997	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.003	0.997	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.003	0.997	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.003	0.997	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.003	0.997	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.997	0.003
H18.8 Other specified disorders of cornea	0.003	0.997	0.000
H70.8 Other mastoiditis and related conditions	0.000	0.997	0.003
C45 Mesothelioma	0.000	0.997	0.003
D47.1 Chronic myeloproliferative disease	0.000	0.997	0.003
M21.83 Other specified acquired deformities of limbs (Forearm)	0.003	0.997	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.003	0.997	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.003	0.997	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.003	0.997	0.000
M25.8 Other specified joint disorders	0.003	0.997	0.000
S02.4 Fracture of malar and maxillary bones	0.000	0.997	0.003
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.003	0.997	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.003	0.997	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.003	0.997	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.003	0.997	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.003	0.997	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.003	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.997	0.003
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.000	0.997	0.003
D86.3 Sarcoidosis of skin	0.000	0.997	0.003
M25.81 Other specified joint disorders (Shoulder region)	0.003	0.997	0.000
B37.8 Candidiasis of other sites	0.000	0.997	0.003
D83.9 Common variable immunodeficiency, unspecified	0.000	0.997	0.003
D81 Combined immunodeficiencies	0.000	0.997	0.003
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.003	0.997	0.000
S22.30 Fracture of rib (closed)	0.000	0.997	0.003
D86.9 Sarcoidosis, unspecified	0.000	0.997	0.003
L29.2 Pruritus vulvae	0.000	0.997	0.003
M21.2 Flexion deformity	0.003	0.997	0.000
C45.7 Mesothelioma of other sites	0.000	0.997	0.003
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.003	0.997	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.997	0.003
M25.83 Other specified joint disorders (Forearm)	0.003	0.997	0.000
C48.1 Specified parts of peritoneum	0.000	0.997	0.003
C48.0 Retroperitoneum	0.000	0.997	0.003
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.997	0.003
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.997	0.003
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.997	0.003
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.997	0.003
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.997	0.003
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.997	0.003
C48.2 Peritoneum, unspecified	0.000	0.997	0.003
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.997	0.003
L29.3 Anogenital pruritus, unspecified	0.000	0.997	0.003
L29.1 Pruritus scroti	0.000	0.997	0.003
M25.88 Other specified joint disorders (Other)	0.003	0.997	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.997	0.003
D83.8 Other common variable immunodeficiencies	0.000	0.997	0.003
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.997	0.003
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.997	0.003
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.997	0.003
L29.8 Other pruritus	0.000	0.997	0.003
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.997	0.003
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.997	0.003
Z57.3 Occupational exposure to other air contaminants	0.000	0.997	0.003
R44 Other symptoms and signs involving general sensations and perceptions	0.003	0.997	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.003	0.997	0.000
M21.20 Flexion deformity (Multiple sites)	0.003	0.997	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.003	0.997	0.000
M21.23 Flexion deformity (Forearm)	0.003	0.997	0.000
S82.20 Fracture of shaft of tibia (closed)	0.003	0.997	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.003	0.997	0.000
C45.2 Mesothelioma of pericardium	0.000	0.997	0.003
R79.9 Abnormal finding of blood chemistry, unspecified	0.000	0.997	0.003
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.997	0.003
M25.87 Other specified joint disorders (Ankle and foot)	0.003	0.997	0.000
C45.9 Mesothelioma, unspecified	0.000	0.997	0.003
I62 Other nontraumatic intracranial haemorrhage	0.000	0.997	0.003
F30-F39 Mood [affective] disorders	0.003	0.997	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.002	0.997	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.002	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.997	0.003
M21.25 Flexion deformity (Pelvic region and thigh)	0.002	0.997	0.000
C45.1 Mesothelioma of peritoneum	0.000	0.997	0.002
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.000	0.997	0.002
K42.9 Umbilical hernia without obstruction or gangrene	0.003	0.997	0.000
K04.5 Chronic apical periodontitis	0.000	0.997	0.003
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.997	0.003
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.997	0.002
D81.9 Combined immunodeficiency, unspecified	0.000	0.997	0.002
D81.8 Other combined immunodeficiencies	0.000	0.997	0.002
D81.7 Major histocompatibility complex class II deficiency	0.000	0.997	0.002
D81.6 Major histocompatibility complex class I deficiency	0.000	0.997	0.002
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.997	0.002
D81.4 Nezelof's syndrome	0.000	0.997	0.002
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.997	0.002
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.997	0.002
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.997	0.002
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.997	0.002
G61.9 Inflammatory polyneuropathy, unspecified	0.002	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.003	0.997	0.000
M21.29 Flexion deformity (Site unspecified)	0.002	0.997	0.000
M21.28 Flexion deformity (Other)	0.002	0.997	0.000
M21.21 Flexion deformity (Shoulder region)	0.002	0.997	0.000
Z57.2 Occupational exposure to dust	0.000	0.997	0.003
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.997	0.002
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.997	0.002
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.997	0.002
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.997	0.002
D82.2 Immunodeficiency with short-limbed stature	0.000	0.997	0.002
D82.0 Wiskott-Aldrich syndrome	0.000	0.997	0.002
M25.82 Other specified joint disorders (Upper arm)	0.002	0.997	0.000
H92.0 Otalgia	0.000	0.997	0.002
F34 Persistent mood [affective] disorders	0.002	0.998	0.000
D82.1 Di George's syndrome	0.000	0.998	0.002
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.002	0.998	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.998	0.002
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.998	0.002
R44.2 Other hallucinations	0.002	0.998	0.000
F30 Manic episode	0.002	0.998	0.000
G61 Inflammatory polyneuropathy	0.002	0.998	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.998	0.002
M21.0 Valgus deformity, not elsewhere classified	0.002	0.998	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.000	0.998	0.002
M21.22 Flexion deformity (Upper arm)	0.002	0.998	0.000
F34.0 Cyclothymia	0.002	0.998	0.000
H74.4 Polyp of middle ear	0.000	0.998	0.002
F38 Other mood [affective] disorders	0.002	0.998	0.000
R70.1 Abnormal plasma viscosity	0.002	0.998	0.000
F39 Unspecified mood [affective] disorder	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.998	0.002
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
H18 Other disorders of cornea	0.002	0.998	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.000	0.998	0.002
C46 Kaposi's sarcoma	0.000	0.998	0.002
M21.27 Flexion deformity (Ankle and foot)	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.998	0.002
K59.1 Functional diarrhoea	0.002	0.998	0.000
C49.0 Connective and soft tissue of head, face and neck	0.000	0.998	0.002
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
F30.1 Mania without psychotic symptoms	0.002	0.998	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.002	0.998	0.000
M34.9 Systemic sclerosis, unspecified	0.000	0.998	0.002
M79.00 Rheumatism, unspecified (Multiple sites)	0.002	0.998	0.000
D89.3 Immune reconstitution syndrome	0.000	0.998	0.002
Z64.0 Problems related to unwanted pregnancy	0.000	0.998	0.002
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.998	0.002
Z57 Occupational exposure to risk-factors	0.000	0.998	0.002
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.000	0.998	0.002
E11.5 With peripheral circulatory complications	0.000	0.998	0.002
C49.9 Connective and soft tissue, unspecified	0.000	0.998	0.002
F34.1 Dysthymia	0.002	0.998	0.000
J98.8 Other specified respiratory disorders	0.000	0.998	0.002
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.002	0.998	0.000
F30.0 Hypomania	0.002	0.998	0.000
F38.8 Other specified mood [affective] disorders	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.998	0.002
F34.9 Persistent mood [affective] disorder, unspecified	0.002	0.998	0.000
F34.8 Other persistent mood [affective] disorders	0.002	0.998	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
M21.26 Flexion deformity (Lower leg)	0.002	0.998	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.998	0.002
F38.0 Other single mood [affective] disorders	0.002	0.998	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.002	0.998	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.002	0.998	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.002	0.998	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
F30.8 Other manic episodes	0.002	0.998	0.000
G61.1 Serum neuropathy	0.002	0.998	0.000
R44.3 Hallucinations, unspecified	0.002	0.998	0.000
M34.1 CR(E)ST syndrome	0.000	0.998	0.002
F38.1 Other recurrent mood [affective] disorders	0.002	0.998	0.000
M21.24 Flexion deformity (Hand)	0.002	0.998	0.000
C69.9 Eye, unspecified	0.000	0.998	0.002
F30.2 Mania with psychotic symptoms	0.002	0.998	0.000
H18.7 Other corneal deformities	0.002	0.998	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.002	0.998	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
C46.9 Kaposi's sarcoma, unspecified	0.000	0.998	0.002
C46.8 Kaposi's sarcoma of multiple organs	0.000	0.998	0.002
C46.7 Kaposi's sarcoma of other sites	0.000	0.998	0.002
C46.3 Kaposi's sarcoma of lymph nodes	0.000	0.998	0.002
C46.2 Kaposi's sarcoma of palate	0.000	0.998	0.002
C46.1 Kaposi's sarcoma of soft tissue	0.000	0.998	0.002
C46.0 Kaposi's sarcoma of skin	0.000	0.998	0.002
C47.9 Peripheral nerves and autonomic nervous system, unspecified	0.000	0.998	0.002
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system	0.000	0.998	0.002
C47.6 Peripheral nerves of trunk, unspecified	0.000	0.998	0.002
C47.5 Peripheral nerves of pelvis	0.000	0.998	0.002
C47.4 Peripheral nerves of abdomen	0.000	0.998	0.002
C47.3 Peripheral nerves of thorax	0.000	0.998	0.002
C47.2 Peripheral nerves of lower limb, including hip	0.000	0.998	0.002
C47.1 Peripheral nerves of upper limb, including shoulder	0.000	0.998	0.002
C47.0 Peripheral nerves of head, face and neck	0.000	0.998	0.002
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.998	0.002
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.998	0.002
Z95.4 Presence of other heart-valve replacement	0.002	0.998	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
Z48.9 Surgical follow-up care, unspecified	0.002	0.998	0.000
K05 Gingivitis and periodontal diseases	0.002	0.998	0.000
C49.5 Connective and soft tissue of pelvis	0.000	0.998	0.002
C49.4 Connective and soft tissue of abdomen	0.000	0.998	0.002
F30.9 Manic episode, unspecified	0.002	0.998	0.000
I62.1 Nontraumatic extradural haemorrhage	0.000	0.998	0.002
U80.8 Agent resistant to other penicillin-related antibiotic	0.002	0.998	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.998	0.002
Z57.7 Occupational exposure to vibration	0.000	0.998	0.002
Z57.6 Occupational exposure to extreme temperature	0.000	0.998	0.002
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.998	0.002
Z57.1 Occupational exposure to radiation	0.000	0.998	0.002
Z57.0 Occupational exposure to noise	0.000	0.998	0.002
C49.3 Connective and soft tissue of thorax	0.000	0.998	0.002
H18.3 Changes in corneal membranes	0.002	0.998	0.000
Z98 Other postsurgical states	0.002	0.998	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.998	0.002
D47.4 Osteomyelofibrosis	0.000	0.998	0.002
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.998	0.002
S40.8 Other superficial injuries of shoulder and upper arm	0.000	0.998	0.002
Z57.8 Occupational exposure to other risk-factors	0.000	0.998	0.002
C69 Malignant neoplasm of eye and adnexa	0.000	0.998	0.002
C69.0 Conjunctiva	0.000	0.998	0.002
R63.1 Polydipsia	0.002	0.998	0.000
M34 Systemic sclerosis	0.000	0.998	0.002
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.998	0.002
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M34.8 Other forms of systemic sclerosis	0.000	0.998	0.002
N93.8 Other specified abnormal uterine and vaginal bleeding	0.002	0.998	0.000
S32.50 Fracture of pubis (closed)	0.000	0.998	0.002
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
G02.1 Meningitis in mycoses	0.001	0.998	0.000
H18.2 Other corneal oedema	0.002	0.998	0.000
K05.4 Periodontosis	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
C69.3 Choroid	0.000	0.998	0.002
K05.5 Other periodontal diseases	0.002	0.998	0.000
H92 Otalgia and effusion of ear	0.000	0.998	0.002
S40 Superficial injury of shoulder and upper arm	0.000	0.998	0.002
Z64 Problems related to certain psychosocial circumstances	0.000	0.998	0.002
I34.1 Mitral (valve) prolapse	0.002	0.998	0.000
K05.2 Acute periodontitis	0.001	0.998	0.000
C69.2 Retina	0.000	0.998	0.001
C77.1 Intrathoracic lymph nodes	0.000	0.998	0.002
Chapter VIII Diseases of the ear and mastoid process	0.000	0.998	0.002
C25.9 Pancreas, unspecified	0.002	0.998	0.000
G03.9 Meningitis, unspecified	0.002	0.998	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.002	0.998	0.000
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
D69.4 Other primary thrombocytopenia	0.000	0.998	0.002
S80.7 Multiple superficial injuries of lower leg	0.000	0.998	0.002
C69.6 Orbit	0.000	0.998	0.001
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.998	0.001
H18.4 Corneal degeneration	0.001	0.998	0.000
K05.6 Periodontal disease, unspecified	0.001	0.998	0.000
S22.3 Fracture of rib	0.000	0.998	0.001
C69.8 Overlapping lesion of eye and adnexa	0.000	0.998	0.001
C69.5 Lachrymal gland and duct	0.000	0.998	0.001
C69.4 Ciliary body	0.000	0.998	0.001
C69.1 Cornea	0.000	0.998	0.001
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.998	0.002
I84.7 Unspecified thrombosed haemorrhoids	0.000	0.998	0.002
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.001	0.998	0.000
G31.0 Circumscribed brain atrophy	0.001	0.998	0.000
H92.2 Otorrhagia	0.000	0.998	0.001
K05.1 Chronic gingivitis	0.001	0.998	0.000
N49.2 Inflammatory disorders of scrotum	0.002	0.998	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.998	0.001
R22.2 Localised swelling, mass and lump, trunk	0.002	0.998	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.002	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.001	0.999	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.999	0.001
K05.0 Acute gingivitis	0.001	0.999	0.000
K85.2 Alcohol-induced acute pancreatitis	0.001	0.999	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.999	0.001
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.001	0.999	0.000
S40.0 Contusion of shoulder and upper arm	0.000	0.999	0.001
G31.8 Other specified degenerative diseases of nervous system	0.001	0.999	0.000
Z59.1 Inadequate housing	0.000	0.999	0.001
H18.6 Keratoconus	0.001	0.999	0.000
M34.0 Progressive systemic sclerosis	0.000	0.999	0.001
S40.7 Multiple superficial injuries of shoulder and upper arm	0.000	0.999	0.001
Z64.4 Discord with counsellors	0.000	0.999	0.001
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.000	0.999	0.001
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.000	0.999	0.001
Z64.1 Problems related to multiparity	0.000	0.999	0.001
G03 Meningitis due to other and unspecified causes	0.001	0.999	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.999	0.001
K05.22 Aggressive periodontitis, generalized	0.001	0.999	0.000
M25.86 Other specified joint disorders (Lower leg)	0.001	0.999	0.000
H21.4 Pupillary membranes	0.001	0.999	0.000
H93.9 Disorder of ear, unspecified	0.000	0.999	0.001
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.999	0.001
S12.70 Multiple fractures of cervical spine (closed)	0.001	0.999	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.999	0.001
Q15.0 Congenital glaucoma	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations