TreeWAS – Variant ID: rs150268548

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.999	0.001	0.000
K76 Other diseases of liver	0.997	0.003	0.000
K70-K77 Diseases of liver	0.994	0.006	0.000
K74 Fibrosis and cirrhosis of liver	0.968	0.032	0.000
K70 Alcoholic liver disease	0.959	0.041	0.000
K74.6 Other and unspecified cirrhosis of liver	0.958	0.042	0.000
E11.9 Without complications	0.896	0.104	0.000
K76.6 Portal hypertension	0.875	0.124	0.000
E11 Non-insulin-dependent diabetes mellitus	0.874	0.126	0.000
K70.4 Alcoholic hepatic failure	0.862	0.138	0.000
E10-E14 Diabetes mellitus	0.842	0.158	0.000
K75 Other inflammatory liver diseases	0.813	0.187	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.811	0.189	0.000
# Top node	0.804	0.196	0.000
Chapter XI Diseases of the digestive system	0.799	0.201	0.000
Chapter XX External causes of morbidity and mortality	0.797	0.203	0.000
K70.3 Alcoholic cirrhosis of liver	0.792	0.208	0.000
K70.9 Alcoholic liver disease, unspecified	0.788	0.212	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.782	0.218	0.000
K50-K52 Noninfective enteritis and colitis	0.781	0.219	0.000
K51 Ulcerative colitis	0.781	0.219	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.780	0.220	0.000
E11.3 With ophthalmic complications	0.779	0.221	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.778	0.222	0.000
W00-W19 Falls	0.778	0.222	0.000
K70.1 Alcoholic hepatitis	0.775	0.225	0.000
E20-E35 Disorders of other endocrine glands	0.774	0.226	0.000
K76.8 Other specified diseases of liver	0.770	0.230	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.769	0.231	0.000
O42 Premature rupture of membranes	0.767	0.233	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.766	0.234	0.000
Chapter VII Diseases of the eye and adnexa	0.765	0.235	0.000
H53-H54 Visual disturbances and blindness	0.760	0.240	0.000
E23 Hypofunction and other disorders of pituitary gland	0.757	0.243	0.000
O42.9 Premature rupture of membranes, unspecified	0.756	0.244	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.746	0.254	0.000
H53 Visual disturbances	0.746	0.254	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.742	0.258	0.000
K75.8 Other specified inflammatory liver diseases	0.740	0.260	0.000
K51.2 Ulcerative (chronic) proctitis	0.735	0.265	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.717	0.283	0.000
E23.2 Diabetes insipidus	0.716	0.284	0.000
K76.7 Hepatorenal syndrome	0.715	0.285	0.000
K76.5 Hepatic veno-occlusive disease	0.715	0.285	0.000
K76.4 Peliosis hepatis	0.715	0.285	0.000
K76.3 Infarction of liver	0.715	0.285	0.000
K76.2 Central haemorrhagic necrosis of liver	0.715	0.285	0.000
K76.1 Chronic passive congestion of liver	0.715	0.285	0.000
K74.0 Hepatic fibrosis	0.713	0.287	0.000
K77 Liver disorders in diseases classified elsewhere	0.712	0.287	0.000
K71 Toxic liver disease	0.712	0.287	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.711	0.289	0.000
K73 Chronic hepatitis, not elsewhere classified	0.709	0.291	0.000
S90-S99 Injuries to the ankle and foot	0.709	0.291	0.000
Q50-Q56 Congenital malformations of genital organs	0.704	0.296	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.698	0.302	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.696	0.304	0.000
E14 Unspecified diabetes mellitus	0.694	0.306	0.000
K74.4 Secondary biliary cirrhosis	0.694	0.306	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.694	0.306	0.000
K74.1 Hepatic sclerosis	0.694	0.306	0.000
H53.4 Visual field defects	0.694	0.306	0.000
K51.8 Other ulcerative colitis	0.693	0.307	0.000
H30-H36 Disorders of choroid and retina	0.689	0.311	0.000
H54 Blindness and low vision	0.689	0.311	0.000
W13 Fall from, out of or through building or structure	0.688	0.312	0.000
K70.0 Alcoholic fatty liver	0.688	0.312	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.687	0.313	0.000
W19 Unspecified fall	0.687	0.313	0.000
S50-S59 Injuries to the elbow and forearm	0.686	0.314	0.000
E23.0 Hypopituitarism	0.683	0.317	0.000
O85-O92 Complications predominantly related to the puerperium	0.682	0.318	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.682	0.318	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.682	0.318	0.000
H53.8 Other visual disturbances	0.678	0.322	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.674	0.326	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.669	0.331	0.000
S10-S19 Injuries to the neck	0.668	0.332	0.000
W17 Other fall from one level to another	0.668	0.332	0.000
E11.8 With unspecified complications	0.667	0.333	0.000
W50-W64 Exposure to animate mechanical forces	0.667	0.333	0.000
H53.2 Diplopia	0.665	0.335	0.000
K51.5 Mucosal proctocolitis	0.661	0.339	0.000
E11.0 With coma	0.660	0.340	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.657	0.343	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.006	0.348	0.645
W19.4 Street and highway	0.651	0.349	0.000
O40 Polyhydramnios	0.649	0.351	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.649	0.351	0.000
E11.1 With ketoacidosis	0.646	0.354	0.000
K75.9 Inflammatory liver disease, unspecified	0.644	0.356	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.642	0.358	0.000
E11.2 With renal complications	0.642	0.358	0.000
H55-H59 Other disorders of eye and adnexa	0.640	0.360	0.000
Y00-Y09 Assault	0.640	0.360	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.639	0.361	0.000
K51.9 Ulcerative colitis, unspecified	0.639	0.361	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.639	0.361	0.000
X10-X19 Contact with heat and hot substances	0.638	0.362	0.000
Chapter I Certain infectious and parasitic diseases	0.634	0.366	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.634	0.366	0.000
K74.5 Biliary cirrhosis, unspecified	0.633	0.367	0.000
S31 Open wound of abdomen, lower back and pelvis	0.633	0.367	0.000
S51 Open wound of forearm	0.631	0.369	0.000
E11.7 With multiple complications	0.627	0.373	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.625	0.375	0.000
W13.9 Unspecified place	0.624	0.376	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.624	0.376	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.624	0.376	0.000
T79-T79 Certain early complications of trauma	0.623	0.377	0.000
H35 Other retinal disorders	0.623	0.377	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.622	0.378	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.619	0.381	0.000
E14.9 Without complications	0.618	0.382	0.000
O43 Placental disorders	0.617	0.383	0.000
Chapter VIII Diseases of the ear and mastoid process	0.617	0.383	0.000
O44 Placenta praevia	0.616	0.384	0.000
H54.4 Blindness, one eye	0.614	0.386	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.613	0.386	0.000
W10 Fall on and from stairs and steps	0.613	0.387	0.000
S90 Superficial injury of ankle and foot	0.610	0.390	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.610	0.390	0.000
E28 Ovarian dysfunction	0.610	0.390	0.000
W20-W49 Exposure to inanimate mechanical forces	0.608	0.392	0.000
T43.2 Other and unspecified antidepressants	0.604	0.396	0.000
E12 Malnutrition-related diabetes mellitus	0.604	0.396	0.000
T00-T07 Injuries involving multiple body regions	0.603	0.397	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.602	0.398	0.000
K76.9 Liver disease, unspecified	0.602	0.398	0.000
X60-X84 Intentional self-harm	0.599	0.400	0.000
E13 Other specified diabetes mellitus	0.599	0.401	0.000
E40-E46 Malnutrition	0.599	0.401	0.000
Q24 Other congenital malformations of heart	0.598	0.402	0.000
H54.7 Unspecified visual loss	0.597	0.403	0.000
H35.8 Other specified retinal disorders	0.596	0.404	0.000
W18 Other fall on same level	0.594	0.406	0.000
O00-O08 Pregnancy with abortive outcome	0.581	0.410	0.009
E24 Cushing's syndrome	0.589	0.411	0.000
Y95 Nosocomial condition	0.589	0.411	0.000
O34.4 Maternal care for other abnormalities of cervix	0.587	0.413	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.584	0.416	0.000
S12 Fracture of neck	0.584	0.416	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.583	0.417	0.000
K75.2 Nonspecific reactive hepatitis	0.583	0.417	0.000
K75.1 Phlebitis of portal vein	0.583	0.417	0.000
Q51 Congenital malformations of uterus and cervix	0.583	0.417	0.000
E34 Other endocrine disorders	0.581	0.418	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.580	0.420	0.000
Q80-Q89 Other congenital malformations	0.580	0.420	0.000
V40-V49 Car occupant injured in transport accident	0.579	0.421	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.578	0.422	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.576	0.424	0.000
H36 Retinal disorders in diseases classified elsewhere	0.575	0.425	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.575	0.425	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.574	0.426	0.000
E11.4 With neurological complications	0.573	0.427	0.000
O86 Other puerperal infections	0.572	0.428	0.000
Y35-Y36 Legal intervention and operations of war	0.572	0.428	0.000
Y10-Y34 Event of undetermined intent	0.572	0.428	0.000
X85-X99 Assault	0.572	0.428	0.000
X30-X39 Exposure to forces of nature	0.572	0.428	0.000
X00-X09 Exposure to smoke, fire and flames	0.572	0.428	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.572	0.428	0.000
W75-W84 Other accidental threats to breathing	0.572	0.428	0.000
W65-W74 Accidental drowning and submersion	0.572	0.428	0.000
V98-V99 Other and unspecified transport accidents	0.572	0.428	0.000
V95-V97 Air and space transport accidents	0.572	0.428	0.000
V90-V94 Water transport accidents	0.572	0.428	0.000
V70-V79 Bus occupant injured in transport accident	0.572	0.428	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.572	0.428	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.572	0.428	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.572	0.428	0.000
V01-V09 Pedestrian injured in transport accident	0.572	0.428	0.000
E23.7 Disorder of pituitary gland, unspecified	0.570	0.430	0.000
E11.6 With other specified complications	0.569	0.431	0.000
E78.2 Mixed hyperlipidaemia	0.003	0.431	0.566
O35 Maternal care for known or suspected foetal abnormality and damage	0.568	0.432	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.568	0.432	0.000
E10 Insulin-dependent diabetes mellitus	0.566	0.434	0.000
H55 Nystagmus and other irregular eye movements	0.564	0.436	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.564	0.436	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.564	0.436	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.562	0.438	0.000
Q23 Congenital malformations of aortic and mitral valves	0.562	0.438	0.000
W07 Fall involving chair	0.561	0.439	0.000
H53.9 Visual disturbance, unspecified	0.560	0.440	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.560	0.440	0.000
O45 Premature separation of placenta [abruptio placentae]	0.560	0.440	0.000
O33 Maternal care for known or suspected disproportion	0.560	0.440	0.000
O31 Complications specific to multiple gestation	0.560	0.440	0.000
O00 Ectopic pregnancy	0.556	0.441	0.004
Q00-Q07 Congenital malformations of the nervous system	0.558	0.441	0.000
W17.5 Trade and service area	0.558	0.442	0.000
T40.4 Other synthetic narcotics	0.558	0.442	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.558	0.442	0.000
Q35-Q37 Cleft lip and cleft palate	0.558	0.442	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.558	0.442	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.558	0.442	0.000
W15 Fall from cliff	0.558	0.442	0.000
W14 Fall from tree	0.558	0.442	0.000
W12 Fall on and from scaffolding	0.558	0.442	0.000
W11 Fall on and from ladder	0.558	0.442	0.000
W09 Fall involving playground equipment	0.558	0.442	0.000
W05 Fall involving wheelchair	0.558	0.442	0.000
W04 Fall while being carried or supported by other persons	0.558	0.442	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.558	0.442	0.000
W00 Fall on same level involving ice and snow	0.558	0.442	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.558	0.442	0.000
X50-X57 Overexertion, travel and privation	0.555	0.444	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.555	0.445	0.000
E32 Diseases of thymus	0.555	0.445	0.000
E31 Polyglandular dysfunction	0.555	0.445	0.000
E30 Disorders of puberty, not elsewhere classified	0.555	0.445	0.000
E26 Hyperaldosteronism	0.555	0.445	0.000
E25 Adrenogenital disorders	0.555	0.445	0.000
E20 Hypoparathyroidism	0.555	0.445	0.000
H65-H75 Diseases of middle ear and mastoid	0.555	0.445	0.000
B25-B34 Other viral diseases	0.554	0.446	0.000
S51.7 Multiple open wounds of forearm	0.553	0.447	0.000
E21.0 Primary hyperparathyroidism	0.552	0.448	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.552	0.448	0.000
T33-T35 Frostbite	0.551	0.449	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.551	0.449	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.551	0.449	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.550	0.450	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.549	0.451	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.549	0.451	0.000
O34.6 Maternal care for abnormality of vagina	0.549	0.451	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.549	0.451	0.000
O34.3 Maternal care for cervical incompetence	0.549	0.451	0.000
O34.0 Maternal care for congenital malformation of uterus	0.549	0.451	0.000
O87 Venous complications in the puerperium	0.548	0.452	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.548	0.452	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.546	0.454	0.000
E78.8 Other disorders of lipoprotein metabolism	0.003	0.454	0.543
V80-V89 Other land transport accidents	0.546	0.454	0.000
S36 Injury of intra-abdominal organs	0.544	0.456	0.000
T42.4 Benzodiazepines	0.543	0.457	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.543	0.457	0.000
E23.6 Other disorders of pituitary gland	0.543	0.457	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.543	0.457	0.000
E23.1 Drug-induced hypopituitarism	0.543	0.457	0.000
O48 Prolonged pregnancy	0.540	0.460	0.000
B99-B99 Other infectious diseases	0.540	0.460	0.000
Q76 Congenital malformations of spine and bony thorax	0.540	0.460	0.000
H43-H45 Disorders of vitreous body and globe	0.540	0.460	0.000
S51.0 Open wound of elbow	0.538	0.462	0.000
E11.5 With peripheral circulatory complications	0.538	0.462	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.537	0.463	0.000
O34.1 Maternal care for tumour of corpus uteri	0.536	0.464	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.535	0.465	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.535	0.465	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.535	0.465	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.535	0.465	0.000
T36 Poisoning by systemic antibiotics	0.535	0.465	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.535	0.465	0.000
H53.6 Night blindness	0.535	0.465	0.000
H53.5 Colour vision deficiencies	0.535	0.465	0.000
H53.3 Other disorders of binocular vision	0.535	0.465	0.000
S91 Open wound of ankle and foot	0.534	0.466	0.000
E50-E64 Other nutritional deficiencies	0.533	0.467	0.000
W17.4 Street and highway	0.533	0.467	0.000
B35-B49 Mycoses	0.532	0.468	0.000
O00.1 Tubal pregnancy	0.531	0.468	0.001
S50 Superficial injury of forearm	0.532	0.468	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.532	0.468	0.000
W60 Contact with plant thorns and spines and sharp leaves	0.531	0.469	0.000
K74.3 Primary biliary cirrhosis	0.530	0.470	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.529	0.471	0.000
W08 Fall involving other furniture	0.529	0.471	0.000
S92 Fracture of foot, except ankle	0.529	0.471	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.527	0.472	0.000
K51.4 Pseudopolyposis of colon	0.527	0.473	0.000
W19.3 Sports and athletics area	0.527	0.473	0.000
O47 False labour	0.527	0.473	0.000
S70-S79 Injuries to the hip and thigh	0.526	0.474	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.526	0.474	0.000
Q78 Other osteochondrodysplasias	0.525	0.475	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.524	0.476	0.000
X10 Contact with hot drinks, food, fats and cooking oils	0.524	0.476	0.000
T40.6 Other and unspecified narcotics	0.524	0.476	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.523	0.477	0.000
Y04 Assault by bodily force	0.523	0.477	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.522	0.478	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.521	0.479	0.000
O41 Other disorders of amniotic fluid and membranes	0.520	0.480	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.520	0.480	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.519	0.481	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.518	0.481	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.518	0.482	0.000
S40-S49 Injuries to the shoulder and upper arm	0.516	0.484	0.000
Q66 Congenital deformities of feet	0.515	0.484	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.515	0.485	0.000
Q28 Other congenital malformations of circulatory system	0.515	0.485	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.514	0.486	0.000
S37 Injury of urinary and pelvic organs	0.514	0.486	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.514	0.486	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.514	0.486	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.514	0.486	0.000
Q24.8 Other specified congenital malformations of heart	0.514	0.486	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.514	0.486	0.000
T66-T78 Other and unspecified effects of external causes	0.514	0.486	0.000
Q27 Other congenital malformations of peripheral vascular system	0.514	0.486	0.000
X20-X29 Contact with venomous animals and plants	0.513	0.487	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.512	0.488	0.000
S14 Injury of nerves and spinal cord at neck level	0.512	0.488	0.000
X59 Exposure to unspecified factor	0.512	0.488	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.511	0.489	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.511	0.489	0.000
K71.9 Toxic liver disease, unspecified	0.511	0.489	0.000
K71.8 Toxic liver disease with other disorders of liver	0.511	0.489	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.511	0.489	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.511	0.489	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.511	0.489	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.511	0.489	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.511	0.489	0.000
K71.2 Toxic liver disease with acute hepatitis	0.511	0.489	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.511	0.489	0.000
K71.0 Toxic liver disease with cholestasis	0.511	0.489	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.511	0.489	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.511	0.489	0.000
T43.9 Psychotropic drug, unspecified	0.510	0.490	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.510	0.490	0.000
T43.6 Psychostimulants with abuse potential	0.510	0.490	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.510	0.490	0.000
Q21 Congenital malformations of cardiac septa	0.509	0.491	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.509	0.491	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.509	0.491	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.509	0.491	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.509	0.491	0.000
V20-V29 Motorcycle rider injured in transport accident	0.508	0.492	0.000
S98 Traumatic amputation of ankle and foot	0.508	0.492	0.000
S97 Crushing injury of ankle and foot	0.508	0.492	0.000
S95 Injury of blood vessels at ankle and foot level	0.508	0.492	0.000
S94 Injury of nerves at ankle and foot level	0.508	0.492	0.000
W20 Struck by thrown, projected or falling object	0.508	0.492	0.000
W10.8 Other specified place	0.508	0.492	0.000
S56 Injury of muscle and tendon at forearm level	0.507	0.492	0.000
K72 Hepatic failure, not elsewhere classified	0.507	0.493	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.506	0.494	0.000
B34 Viral infection of unspecified site	0.505	0.495	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.505	0.495	0.000
Q55 Other congenital malformations of male genital organs	0.505	0.495	0.000
Q53 Undescended testicle	0.505	0.495	0.000
Q52 Other congenital malformations of female genitalia	0.505	0.495	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.504	0.496	0.000
A65-A69 Other spirochaetal diseases	0.504	0.496	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.504	0.496	0.000
S31.0 Open wound of lower back and pelvis	0.503	0.496	0.000
V10-V19 Pedal cyclist injured in transport accident	0.501	0.498	0.000
O90 Complications of the puerperium, not elsewhere classified	0.501	0.499	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.501	0.499	0.000
Q26 Congenital malformations of great veins	0.501	0.499	0.000
Q25 Congenital malformations of great arteries	0.501	0.499	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.501	0.499	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.501	0.499	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.500	0.500	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.003	0.500	0.496
Y46 Antiepileptics and anti-Parkinsonism drugs	0.499	0.501	0.000
E28.2 Polycystic ovarian syndrome	0.498	0.502	0.000
E14.8 With unspecified complications	0.498	0.502	0.000
E14.7 With multiple complications	0.498	0.502	0.000
E14.6 With other specified complications	0.498	0.502	0.000
E14.5 With peripheral circulatory complications	0.498	0.502	0.000
E14.4 With neurological complications	0.498	0.502	0.000
E14.2 Withrenal complications	0.498	0.502	0.000
E14.1 With ketoacidosis	0.498	0.502	0.000
E14.0 With coma	0.498	0.502	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.497	0.502	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.497	0.503	0.000
O86.2 Urinary tract infection following delivery	0.497	0.503	0.000
H35.9 Retinal disorder, unspecified	0.496	0.504	0.000
Y44 Agents primarily affecting blood constituents	0.496	0.504	0.000
W02.9 Unspecified place	0.495	0.504	0.000
S59 Other and unspecified injuries of forearm	0.495	0.505	0.000
O43.8 Other placental disorders	0.495	0.505	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.494	0.506	0.000
H30 Chorioretinal inflammation	0.494	0.506	0.000
H54.6 Unqualified visual loss, one eye	0.494	0.506	0.000
H54.5 Low vision, one eye	0.494	0.506	0.000
H54.3 Unqualified visual loss, both eyes	0.494	0.506	0.000
H54.2 Low vision, both eyes	0.494	0.506	0.000
H54.1 Blindness, one eye, low vision, other eye	0.494	0.506	0.000
S93.0 Dislocation of ankle joint	0.494	0.506	0.000
W13.8 Other specified place	0.494	0.506	0.000
W13.0 Home	0.494	0.506	0.000
W13.7 Farm	0.494	0.506	0.000
W13.6 Industrial and construction area	0.494	0.506	0.000
W13.5 Trade and service area	0.494	0.506	0.000
W13.4 Street and highway	0.494	0.506	0.000
W13.3 Sports and athletics area	0.494	0.506	0.000
W13.2 School, other institution and public administrative area	0.494	0.506	0.000
W13.1 Residential institution	0.494	0.506	0.000
H36.0 Diabetic retinopathy	0.493	0.507	0.000
B95-B98 Bacterial, viral and other infectious agents	0.493	0.507	0.000
W19.8 Other specified place	0.492	0.508	0.000
W19.5 Trade and service area	0.492	0.508	0.000
W19.0 Home	0.492	0.508	0.000
W19.7 Farm	0.492	0.508	0.000
W19.6 Industrial and construction area	0.492	0.508	0.000
W19.1 Residential institution	0.492	0.508	0.000
S58 Traumatic amputation of forearm	0.492	0.508	0.000
S57 Crushing injury of forearm	0.492	0.508	0.000
S55 Injury of blood vessels at forearm level	0.492	0.508	0.000
S54 Injury of nerves at forearm level	0.492	0.508	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.492	0.508	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.491	0.509	0.000
H31 Other disorders of choroid	0.491	0.509	0.000
Q54 Hypospadias	0.491	0.509	0.000
H53.0 Amblyopia ex anopsia	0.490	0.510	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.490	0.510	0.000
S31.4 Open wound of vagina and vulva	0.490	0.510	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.489	0.510	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.489	0.511	0.000
O91 Infections of breast associated with childbirth	0.489	0.511	0.000
O89 Complications of anaesthesia during the puerperium	0.489	0.511	0.000
O88 Obstetric embolism	0.489	0.511	0.000
O85 Puerperal sepsis	0.489	0.511	0.000
S90.0 Contusion of ankle	0.489	0.511	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.489	0.511	0.000
Y98 Lifestyle-related condition	0.489	0.511	0.000
Y97 Environmental-pollution-related condition	0.489	0.511	0.000
Y96 Work-related condition	0.489	0.511	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.489	0.511	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.489	0.511	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.489	0.511	0.000
W18.5 Trade and service area	0.489	0.511	0.000
T51 Toxic effect of alcohol	0.489	0.511	0.000
E78.1 Pure hyperglyceridaemia	0.004	0.513	0.483
H10-H13 Disorders of conjunctiva	0.485	0.515	0.000
Q51.2 Other doubling of uterus	0.484	0.516	0.000
T02 Fractures involving multiple body regions	0.484	0.516	0.000
Y48 Anaesthetics and therapeutic gases	0.484	0.516	0.000
H72 Perforation of tympanic membrane	0.483	0.517	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.483	0.517	0.000
Q75 Other congenital malformations of skull and face bones	0.483	0.517	0.000
Q74 Other congenital malformations of limb(s)	0.483	0.517	0.000
Q73 Reduction defects of unspecified limb	0.483	0.517	0.000
Q72 Reduction defects of lower limb	0.483	0.517	0.000
Q71 Reduction defects of upper limb	0.483	0.517	0.000
Q70 Syndactyly	0.483	0.517	0.000
Q69 Polydactyly	0.483	0.517	0.000
Q68 Other congenital musculoskeletal deformities	0.483	0.517	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.483	0.517	0.000
S90.8 Other superficial injuries of ankle and foot	0.483	0.517	0.000
H54.9 Unspecified visual impairment (binocular)	0.483	0.517	0.000
Q65 Congenital deformities of hip	0.480	0.520	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.480	0.520	0.000
E10.1 With ketoacidosis	0.480	0.520	0.000
S17 Crushing injury of neck	0.479	0.521	0.000
S15 Injury of blood vessels at neck level	0.479	0.521	0.000
S11 Open wound of neck	0.479	0.521	0.000
S18 Traumatic amputation at neck level	0.479	0.521	0.000
S16 Injury of muscle and tendon at neck level	0.479	0.521	0.000
W17.9 Unspecified place	0.479	0.521	0.000
W17.8 Other specified place	0.479	0.521	0.000
W17.0 Home	0.479	0.521	0.000
W17.7 Farm	0.479	0.521	0.000
W17.6 Industrial and construction area	0.479	0.521	0.000
W17.3 Sports and athletics area	0.479	0.521	0.000
W17.2 School, other institution and public administrative area	0.479	0.521	0.000
W17.1 Residential institution	0.479	0.521	0.000
Q83 Congenital malformations of breast	0.478	0.522	0.000
W64 Exposure to other and unspecified animate mechanical forces	0.478	0.522	0.000
W59 Bitten or crushed by other reptiles	0.478	0.522	0.000
W58 Bitten or struck by crocodile or alligator	0.478	0.522	0.000
W56 Contact with marine animal	0.478	0.522	0.000
W54 Bitten or struck by dog	0.478	0.522	0.000
W53 Bitten by rat	0.478	0.522	0.000
W52 Crushed, pushed and stepped on by crowd or human stampede	0.478	0.522	0.000
W51 Striking against or bumped into by another person	0.478	0.522	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.477	0.523	0.000
H35.2 Other proliferative retinopathy	0.476	0.523	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.475	0.524	0.000
H33 Retinal detachments and breaks	0.475	0.525	0.000
S10 Superficial injury of neck	0.475	0.525	0.000
H50 Other strabismus	0.474	0.526	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.474	0.526	0.000
O44.1 Placenta praevia with haemorrhage	0.473	0.526	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.473	0.527	0.000
B99 Other and unspecified infectious diseases	0.473	0.527	0.000
Y40 Systemic antibiotics	0.472	0.528	0.000
K75.0 Abscess of liver	0.472	0.528	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.471	0.529	0.000
H71 Cholesteatoma of middle ear	0.471	0.529	0.000
O47.9 False labour, unspecified	0.470	0.530	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.470	0.530	0.000
S12.1 Fracture of second cervical vertebra	0.469	0.531	0.000
Q12 Congenital lens malformations	0.468	0.532	0.000
Y52 Agents primarily affecting the cardiovascular system	0.467	0.533	0.000
E78.6 Lipoprotein deficiency	0.005	0.533	0.463
E78.3 Hyperchylomicronaemia	0.005	0.533	0.463
K50 Crohn's disease [regional enteritis]	0.467	0.533	0.000
H35.7 Separation of retinal layers	0.467	0.533	0.000
B50-B64 Protozoal diseases	0.466	0.534	0.000
Y59 Other and unspecified vaccines and biological substances	0.465	0.535	0.000
Y58 Bacterial vaccines	0.465	0.535	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.465	0.535	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.465	0.535	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations