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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1533665
log Bayes Factor = <0.0001
Chromosome 15   position 78,530,940  (GRCh37) Explore rs1533665 on Ensembl!
Variant rs1533665 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D05.9 Carcinoma in situ of breast, unspecified
0.053 0.947 0.000
B18.2 Chronic viral hepatitis C
0.053 0.947 0.000
B18 Chronic viral hepatitis
0.041 0.959 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.035 0.965 0.000
D05 Carcinoma in situ of breast
0.034 0.966 0.000
B18.9 Chronic viral hepatitis, unspecified
0.030 0.970 0.000
B18.8 Other chronic viral hepatitis
0.030 0.970 0.000
B18.0 Chronic viral hepatitis B with delta-agent
0.030 0.970 0.000
H65.3 Chronic mucoid otitis media
0.000 0.972 0.028
D04 Carcinoma in situ of skin
0.027 0.973 0.000
B15-B19 Viral hepatitis
0.027 0.973 0.000
D00-D09 In situ neoplasms
0.027 0.973 0.000
D04.3 Skin of other and unspecified parts of face
0.026 0.974 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.000 0.974 0.026
D05.1 Intraductal carcinoma in situ
0.025 0.975 0.000
H65 Nonsuppurative otitis media
0.000 0.976 0.024
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.023 0.977 0.000
B19 Unspecified viral hepatitis
0.023 0.977 0.000
Y43.3 Other antineoplastic drugs
0.023 0.977 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.023 0.977 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.022 0.978 0.000
D04.4 Skin of scalp and neck
0.022 0.978 0.000
D04.7 Skin of lower limb, including hip
0.022 0.978 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.022 0.978 0.000
D05.7 Other carcinoma in situ of breast
0.022 0.978 0.000
B17 Other acute viral hepatitis
0.022 0.978 0.000
D09 Carcinoma in situ of other and unspecified sites
0.021 0.978 0.000
C83.3 Large cell (diffuse)
0.021 0.979 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.021 0.979 0.000
D05.0 Lobular carcinoma in situ
0.021 0.979 0.000
D04.2 Skin of ear and external auricular canal
0.021 0.979 0.000
C90.0 Multiple myeloma
0.021 0.979 0.000
D04.1 Skin of eyelid, including canthus
0.021 0.979 0.000
D04.0 Skin of lip
0.021 0.979 0.000
B19.9 Unspecified viral hepatitis without coma
0.021 0.979 0.000
C92 Myeloid leukaemia
0.020 0.980 0.000
D04.5 Skin of trunk
0.020 0.980 0.000
C92.1 Chronic myeloid leukaemia
0.020 0.980 0.000
C84.5 Other and unspecified T-cell lymphomas
0.020 0.980 0.000
B15 Acute hepatitis A
0.019 0.980 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.019 0.980 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.019 0.981 0.000
D04.8 Skin of other sites
0.019 0.981 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.019 0.981 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.019 0.981 0.000
C91 Lymphoid leukaemia
0.018 0.982 0.000
C84.0 Mycosis fungoides
0.018 0.982 0.000
D06 Carcinoma in situ of cervix uteri
0.018 0.982 0.000
C88 Malignant immunoproliferative diseases
0.018 0.982 0.000
H65.4 Other chronic nonsuppurative otitis media
0.000 0.982 0.018
D07.5 Prostate
0.018 0.982 0.000
B17.1 Acute hepatitis C
0.017 0.982 0.000
C84.4 Peripheral T-cell lymphoma
0.017 0.983 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.017 0.983 0.000
C90.2 Plasmacytoma, extramedullary
0.017 0.983 0.000
B16 Acute hepatitis B
0.017 0.983 0.000
C93 Monocytic leukaemia
0.017 0.983 0.000
B17.9 Acute viral hepatitis, unspecified
0.017 0.983 0.000
C91.0 Acute lymphoblastic leukaemia
0.017 0.983 0.000
H65.0 Acute serous otitis media
0.000 0.983 0.017
B19.0 Unspecified viral hepatitis with coma
0.017 0.983 0.000
D09.7 Carcinoma in situ of other specified sites
0.017 0.983 0.000
C92.7 Other myeloid leukaemia
0.017 0.983 0.000
D09.9 Carcinoma in situ, unspecified
0.016 0.984 0.000
C83.1 Small cleaved cell (diffuse)
0.016 0.984 0.000
C83.6 Undifferentiated (diffuse)
0.016 0.984 0.000
C83.4 Immunoblastic (diffuse)
0.016 0.984 0.000
C83.2 Mixed small and large cell (diffuse)
0.016 0.984 0.000
B17.2 Acute hepatitis E
0.016 0.984 0.000
D09.1 Other and unspecified urinary organs
0.016 0.984 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.016 0.984 0.000
H65.2 Chronic serous otitis media
0.000 0.984 0.016
C84.9 Mature T/NK-cell lymphoma, unspecified
0.016 0.984 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.016 0.984 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.016 0.984 0.000
C84.3 Lymphoepithelioid lymphoma
0.016 0.984 0.000
C84.2 T-zone lymphoma
0.016 0.984 0.000
C84.1 Sezary's diease
0.016 0.984 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.016 0.984 0.000
C92.9 Myeloid leukaemia, unspecified
0.016 0.984 0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier
0.016 0.984 0.000
H65.1 Other acute nonsuppurative otitis media
0.000 0.984 0.016
D09.3 Thyroid and other endocrine glands
0.016 0.984 0.000
D09.2 Eye
0.016 0.984 0.000
D09.0 Bladder
0.016 0.984 0.000
C83.5 Lymphoblastic (diffuse)
0.016 0.984 0.000
C92.5 Acute myelomonocytic leukaemia
0.016 0.984 0.000
D07.2 Vagina
0.015 0.984 0.000
C90.1 Plasma cell leukaemia
0.015 0.984 0.000
D04.9 Skin, unspecified
0.015 0.985 0.000
C83.7 Burkitt's tumour
0.015 0.985 0.000
C94 Other leukaemias of specified cell type
0.015 0.985 0.000
C91.4 Hairy-cell leukaemia
0.015 0.985 0.000
D06.0 Endocervix
0.015 0.985 0.000
D03 Melanoma in situ
0.015 0.985 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.015 0.985 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.015 0.985 0.000
C92.3 Myeloid sarcoma
0.015 0.985 0.000
C92.2 Subacute myeloid leukaemia
0.015 0.985 0.000
D07.3 Other and unspecified female genital organs
0.015 0.985 0.000
Y43 Primarily systemic agents
0.015 0.985 0.000
B15.9 Hepatitis A without hepatic coma
0.014 0.985 0.000
D02.0 Larynx
0.014 0.986 0.000
C86 Other specified types of T/NK-cell lymphoma
0.014 0.986 0.000
D02.2 Bronchus and lung
0.014 0.986 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.014 0.986 0.000
B15.0 Hepatitis A with hepatic coma
0.014 0.986 0.000
D02.4 Respiratory system, unspecified
0.014 0.986 0.000
D02.3 Other parts of respiratory system
0.014 0.986 0.000
D02.1 Trachea
0.014 0.986 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.014 0.986 0.000
D07.6 Other and unspecified male genital organs
0.014 0.986 0.000
B17.8 Other specified acute viral hepatitis
0.014 0.986 0.000
D04.6 Skin of upper limb, including shoulder
0.014 0.986 0.000
D00.1 Oesophagus
0.014 0.986 0.000
C93.1 Chronic monocytic leukaemia
0.014 0.986 0.000
D00.2 Stomach
0.014 0.986 0.000
D06.1 Exocervix
0.014 0.986 0.000
C90.3 Solitary plasmacytoma
0.014 0.986 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.014 0.986 0.000
D07.0 Endometrium
0.013 0.986 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.013 0.987 0.000
C91.7 Other lymphoid leukaemia
0.013 0.987 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.013 0.987 0.000
C91.3 Prolymphocytic leukaemia
0.013 0.987 0.000
C91.2 Subacute lymphocytic leukaemia
0.013 0.987 0.000
D06.7 Other parts of cervix
0.013 0.987 0.000
D00.0 Lip, oral cavity and pharynx
0.013 0.987 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.013 0.987 0.000
C88.7 Other malignant immunoproliferative diseases
0.013 0.987 0.000
C88.3 Immunoproliferative small intestinal disease
0.013 0.987 0.000
C88.2 Gamma heavy chain disease
0.013 0.987 0.000
C88.1 Alpha heavy chain disease
0.013 0.987 0.000
D01.9 Digestive organ, unspecified
0.013 0.987 0.000
D01.7 Other specified digestive organs
0.013 0.987 0.000
D01.5 Liver, gallbladder and bile ducts
0.013 0.987 0.000
D01.4 Other and unspecified parts of intestine
0.013 0.987 0.000
D01.1 Rectosigmoid junction
0.013 0.987 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.013 0.987 0.000
B16.2 Acute hepatitis B without delta-agent with hepatic coma
0.012 0.987 0.000
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma
0.012 0.987 0.000
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma
0.012 0.987 0.000
C93.9 Monocytic leukaemia, unspecified
0.012 0.987 0.000
C93.7 Other monocytic leukaemia
0.012 0.987 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.012 0.987 0.000
C93.2 Subacute monocytic leukaemia
0.012 0.987 0.000
C93.0 Acute monocytic leukaemia
0.012 0.987 0.000
D01.0 Colon
0.012 0.987 0.000
D01.2 Rectum
0.012 0.987 0.000
C91.9 Lymphoid leukaemia, unspecified
0.012 0.987 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.012 0.987 0.000
C95 Leukaemia of unspecified cell type
0.012 0.988 0.000
C91.5 Adult T-cell leukaemia
0.012 0.988 0.000
D03.8 Melanoma in situ of other sites
0.012 0.988 0.000
C92.4 Acute promyelocytic leukaemia
0.012 0.988 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.012 0.988 0.000
Y43.2 Antineoplastic natural products
0.012 0.988 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.011 0.988 0.000
C96.8 Histiocytic sarcoma
0.011 0.988 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.011 0.988 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.011 0.988 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.011 0.988 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.011 0.988 0.000
C96.3 True histiocytic lymphoma
0.011 0.988 0.000
C96.2 Malignant mast cell tumour
0.011 0.988 0.000
C96.1 Malignant histiocytosis
0.011 0.988 0.000
C96.0 Letterer-Siwe disease
0.011 0.988 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.011 0.989 0.000
C82.4 Follicular lymphoma grade IIIb
0.011 0.989 0.000
D01.3 Anus and anal canal
0.011 0.989 0.000
Y43.0 Antiallergic and antiemetic drugs
0.011 0.989 0.000
C91.1 Chronic lymphocytic leukaemia
0.011 0.989 0.000
C92.0 Acute myeloid leukaemia
0.011 0.989 0.000
C94.7 Other specified leukaemias
0.011 0.989 0.000
C94.5 Acute myelofibrosis
0.011 0.989 0.000
C94.3 Mast cell leukaemia
0.011 0.989 0.000
C94.2 Acute megakaryoblastic leukaemia
0.011 0.989 0.000
C94.1 Chronic erythraemia
0.011 0.989 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.011 0.989 0.000
C94.4 Acute panmyelosis
0.011 0.989 0.000
D03.9 Melanoma in situ, unspecified
0.011 0.989 0.000
D03.0 Melanoma in situ of lip
0.011 0.989 0.000
Y43.9 Primarily systemic agent, unspecified
0.011 0.989 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.011 0.989 0.000
Y43.6 Enzymes, not elsewhere classified
0.011 0.989 0.000
Y43.5 Acidifying and alkalising agents
0.011 0.989 0.000
C82.0 Small cleaved cell, follicular
0.011 0.989 0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.010 0.989 0.000
C86.4 Blastic NK-cell lymphoma
0.010 0.989 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.010 0.989 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.010 0.989 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.010 0.989 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.010 0.989 0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma
0.010 0.989 0.000
C82.6 Cutaneous follicle centre lymphoma
0.010 0.989 0.000
C82.5 Diffuse follicle centre lymphoma
0.010 0.989 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.010 0.989 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.011 0.989 0.000
Y43.1 Antineoplastic antimetabolites
0.010 0.989 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.010 0.989 0.000
Y43.4 Immunosuppressive agents
0.010 0.990 0.000
D07.4 Penis
0.010 0.990 0.000
C82.3 Follicular lymphoma grade IIIa
0.010 0.990 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.010 0.990 0.000
D03.4 Melanoma in situ of scalp and neck
0.009 0.990 0.000
C83.0 Small cell (diffuse)
0.009 0.991 0.000
D07.1 Vulva
0.009 0.991 0.000
C95.7 Other leukaemia of unspecified cell type
0.009 0.991 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.009 0.991 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.009 0.991 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.009 0.991 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.009 0.991 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.009 0.991 0.000
G44.2 Tension-type headache
0.000 0.991 0.009
R72 Abnormality of white blood cells, not elsewhere classified
0.009 0.991 0.000
D06.9 Cervix, unspecified
0.009 0.991 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.008 0.992 0.000
Q21.1 Atrial septal defect
0.008 0.992 0.000
C95.9 Leukaemia, unspecified
0.008 0.992 0.000
C85.1 B-cell lymphoma, unspecified
0.008 0.992 0.000
Y53.4 Other laxatives
0.008 0.992 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.008 0.992 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.008 0.992 0.000
C85.0 Lymphosarcoma
0.008 0.992 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.008 0.992 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.008 0.992 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.008 0.992 0.000
C95.0 Acute leukaemia of unspecified cell type
0.007 0.993 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.007 0.993 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.007 0.993 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.007 0.993 0.000
Y40.3 Macrolides
0.007 0.993 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.007 0.993 0.000
A41 Other septicaemia
0.007 0.993 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.007 0.993 0.000
Y41.5 Antiviral drugs
0.007 0.993 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.007 0.993 0.000
C82.2 Large cell, follicular
0.007 0.993 0.000
D23.6 Skin of upper limb, including shoulder
0.000 0.993 0.007
A41.5 Septicaemia due to other Gram-negative organisms
0.007 0.993 0.000
Y47.1 Benzodiazepines
0.007 0.993 0.000
Y40 Systemic antibiotics
0.007 0.993 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.007 0.993 0.000
H20 Iridocyclitis
0.007 0.993 0.000
H20.8 Other iridocyclitis
0.007 0.993 0.000
H20.9 Iridocyclitis, unspecified
0.007 0.993 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.007 0.993 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.007 0.993 0.000
C81 Hodgkin's disease
0.006 0.994 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.006 0.994 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.006 0.994 0.000
H18 Other disorders of cornea
0.006 0.994 0.000
D03.5 Melanoma in situ of trunk
0.006 0.994 0.000
Y41.1 Antimycobacterial drugs
0.006 0.994 0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa
0.006 0.994 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.006 0.994 0.000
Y56.3 Emollients, demulcents and protectants
0.006 0.994 0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified
0.006 0.994 0.000
Y41.4 Anthelminthics
0.006 0.994 0.000
Y41.3 Other antiprotozoal drugs
0.006 0.994 0.000
H16 Keratitis
0.006 0.994 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.006 0.994 0.000
T85.2 Mechanical complication of intraocular lens
0.006 0.994 0.000
Y59 Other and unspecified vaccines and biological substances
0.006 0.994 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.006 0.994 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.006 0.994 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.006 0.994 0.000
H18.4 Corneal degeneration
0.006 0.994 0.000
H46 Optic neuritis
0.000 0.994 0.006
H21.5 Other adhesions and disruptions of iris and ciliary body
0.006 0.994 0.000
Q21 Congenital malformations of cardiac septa
0.006 0.994 0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.006 0.994 0.000
Y53.7 Emetics
0.006 0.994 0.000
Y53.6 Antidiarrhoeal drugs
0.006 0.994 0.000
Y53.5 Digestants
0.006 0.994 0.000
Y53.0 Histamine H2-receptor antagonists
0.006 0.994 0.000
Y53.3 Saline and osmotic laxatives
0.006 0.994 0.000
Y58 Bacterial vaccines
0.005 0.994 0.000
H18.9 Disorder of cornea, unspecified
0.006 0.994 0.000
Y42.4 Oral contraceptives
0.006 0.994 0.000
Y53.2 Stimulant laxatives
0.005 0.994 0.000
H18.6 Keratoconus
0.006 0.994 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.005 0.994 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.005 0.994 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.005 0.994 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.005 0.994 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.005 0.995 0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified
0.005 0.995 0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs
0.005 0.995 0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified
0.005 0.995 0.000
Y47.4 Bromine compounds
0.005 0.995 0.000
Y47.3 Paraldehyde
0.005 0.995 0.000
Y47.2 Chloral derivatives
0.005 0.995 0.000
Y47.0 Barbiturates, not elsewhere classified
0.005 0.995 0.000
Y41.0 Sulphonamides
0.005 0.995 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.005 0.995 0.000
G44 Other headache syndromes
0.000 0.995 0.005
Y40.6 Rifamycins
0.005 0.995 0.000
Y56.9 Topical agent, unspecified
0.005 0.995 0.000
Y56.8 Other topical agents
0.005 0.995 0.000
Y56.7 Dental drugs, topically applied
0.005 0.995 0.000
Y56.6 Otorhinolaryngological drugs and preparations
0.005 0.995 0.000
Y56.5 Ophthalmological drugs and preparations
0.005 0.995 0.000
Y56.2 Local astringents and local detergents
0.005 0.995 0.000
Y56.1 Antipruritics
0.005 0.995 0.000
H21 Other disorders of iris and ciliary body
0.005 0.995 0.000
H20.1 Chronic iridocyclitis
0.005 0.995 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.005 0.995 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.005 0.995 0.000
H18.7 Other corneal deformities
0.005 0.995 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.000 0.995 0.005
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.005 0.995 0.000
H16.1 Other superficial keratitis without conjunctivitis
0.005 0.995 0.000
Y40.2 Chloramphenicol group
0.005 0.995 0.000
H20.2 Lens-induced iridocyclitis
0.005 0.995 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.005 0.995 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.005 0.995 0.000
Y40.8 Other systemic antibiotics
0.005 0.995 0.000
Y40.7 Antifungal antibiotics, systemically used
0.005 0.995 0.000
A41.4 Septicaemia due to anaerobes
0.005 0.995 0.000
H18.1 Bullous keratopathy
0.005 0.995 0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.005 0.995 0.000
H16.2 Keratoconjunctivitis
0.005 0.995 0.000
Y40.5 Aminoglycosides
0.005 0.995 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.005 0.995 0.000
Y54.3 Benzothiadiazine derivatives
0.005 0.995 0.000
Y40.4 Tetracyclines
0.005 0.995 0.000
C81.0 Lymphocytic predominance
0.005 0.995 0.000
H16.4 Corneal neovascularisation
0.005 0.995 0.000
Y42.2 Antithyroid drugs
0.005 0.995 0.000
Y48 Anaesthetics and therapeutic gases
0.005 0.995 0.000
A41.8 Other specified septicaemia
0.005 0.995 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.004 0.995 0.000
C81.3 Lymphocytic depletion
0.004 0.995 0.000
H15 Disorders of sclera
0.005 0.995 0.000
H16.8 Other keratitis
0.005 0.995 0.000
Y46.6 Other and unspecified antiepileptics
0.005 0.995 0.000
H16.9 Keratitis, unspecified
0.005 0.995 0.000
G44.0 Cluster headache syndrome
0.000 0.995 0.005
H21.0 Hyphaema
0.005 0.995 0.000
Y55.4 Expectorants
0.005 0.995 0.000
Q23 Congenital malformations of aortic and mitral valves
0.005 0.995 0.000
Y59.0 Viral vaccines
0.005 0.995 0.000
G44.8 Other specified headache syndromes
0.000 0.995 0.005
G44.3 Chronic posttraumatic headache
0.000 0.995 0.005
H18.0 Corneal pigmentations and deposits
0.005 0.995 0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system
0.004 0.995 0.000
Y44 Agents primarily affecting blood constituents
0.005 0.995 0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.005 0.995 0.000
H18.8 Other specified disorders of cornea
0.005 0.995 0.000
Y42.9 Other and unspecified hormone antagonists
0.004 0.995 0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.004 0.995 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.005 0.995 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.004 0.995 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.004 0.995 0.000
Y46.7 Anti-Parkinsonism drugs
0.004 0.995 0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics
0.004 0.995 0.000
H17 Corneal scars and opacities
0.004 0.995 0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere
0.004 0.995 0.000
Y50.9 Central nervous system stimulant, unspecified
0.004 0.995 0.000
Y50.8 Other central nervous system stimulants
0.004 0.995 0.000
Y50.2 Methylxanthines, not elsewhere classified
0.004 0.995 0.000
Y50.1 Opioid receptor antagonists
0.004 0.995 0.000
Y50.0 Analeptics
0.004 0.995 0.000
H22.1 Iridocyclitis in other diseases classified elsewhere
0.004 0.995 0.000
Y59.9 Vaccine or biological substance, unspecified
0.004 0.995 0.000
Y59.8 Other specified vaccines and biological substances
0.004 0.995 0.000
Y59.2 Protozoal vaccines
0.004 0.995 0.000
Y59.1 Rickettsial vaccines
0.004 0.995 0.000
Y46.5 Valproic acid
0.004 0.995 0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.004 0.995 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.004 0.995 0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.004 0.995 0.000
Y51.1 Other parasympathomimetics [cholinergics]
0.004 0.995 0.000
Y51.0 Anticholinesterase agents
0.004 0.995 0.000
H18.3 Changes in corneal membranes
0.004 0.995 0.000
H18.2 Other corneal oedema
0.004 0.996 0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system
0.004 0.996 0.000
Y55.5 Anticommon cold drugs
0.004 0.996 0.000
Y55.3 Antitussives
0.004 0.996 0.000
Y55.2 Other and unspecified agents primarily acting on muscles
0.004 0.996 0.000
Y55.0 Oxytocic drugs
0.004 0.996 0.000
C81.2 Mixed cellularity
0.004 0.996 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.004 0.996 0.000
R44.3 Hallucinations, unspecified
0.004 0.996 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.004 0.996 0.000
Y49.2 Other and unspecified antidepressants
0.004 0.996 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.996 0.004
Q21.4 Aortopulmonary septal defect
0.004 0.996 0.000
Q21.2 Atrioventricular septal defect
0.004 0.996 0.000
H16.3 Interstitial and deep keratitis
0.004 0.996 0.000
Q23.1 Congenital insufficiency of aortic valve
0.004 0.996 0.000
I60 Subarachnoid haemorrhage
0.004 0.996 0.000
Y42.1 Thyroid hormones and substitutes
0.004 0.996 0.000
Y54.4 Loop [high-ceiling] diuretics
0.004 0.996 0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.004 0.996 0.000
Y58.9 Other and unspecified bacterial vaccines
0.004 0.996 0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component
0.004 0.996 0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component
0.004 0.996 0.000
Y58.5 Diphtheria vaccine
0.004 0.996 0.000
Y58.4 Tetanus vaccine
0.004 0.996 0.000
Y58.3 Plague vaccine
0.004 0.996 0.000
Y58.2 Cholera vaccine
0.004 0.996 0.000
Y58.1 Typhoid and paratyphoid vaccine
0.004 0.996 0.000
Y45.1 Salicylates
0.004 0.996 0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics
0.004 0.996 0.000
Y46.8 Antispasticity drugs
0.004 0.996 0.000
Y46.3 Deoxybarbiturates
0.004 0.996 0.000
Y46.1 Oxazolidinediones
0.004 0.996 0.000
Y46.0 Succinimides
0.004 0.996 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.004 0.996 0.000
C81.7 Other Hodgkin's disease
0.004 0.996 0.001
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
0.004 0.996 0.000
Q23.0 Congenital stenosis of aortic valve
0.004 0.996 0.000
Y49.9 Psychotropic drug, unspecified
0.004 0.996 0.000
Y49.8 Other psychotropic drugs, not elsewhere classified
0.004 0.996 0.000
Y49.7 Psychostimulants with abuse potential
0.004 0.996 0.000
Y49.6 Psychodysleptics [hallucinogens]
0.004 0.996 0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants
0.004 0.996 0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere
0.004 0.996 0.000
Y59.3 Immunoglobulin
0.004 0.996 0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere
0.004 0.996 0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere
0.004 0.996 0.000
Y55.6 Antiasthmatics, not elsewhere classified
0.004 0.996 0.000
Y54.9 Mineral salts, not elsewhere classified
0.004 0.996 0.000
Y54.6 Electrolytic, caloric and water-balance agents
0.004 0.996 0.000
Y54.2 Carbonic-anhydrase inhibitors
0.004 0.996 0.000
Q25 Congenital malformations of great arteries
0.004 0.996 0.000
Q21.8 Other congenital malformations of cardiac septa
0.004 0.996 0.000
Q21.0 Ventricular septal defect
0.004 0.996 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.004 0.996 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.004 0.996 0.000
Q23.3 Congenital mitral insufficiency
0.004 0.996 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.004 0.996 0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.004 0.996 0.000
Q25.1 Coarctation of aorta
0.004 0.996 0.000
R44.1 Visual hallucinations
0.004 0.996 0.000
Y58.0 BCG vaccine
0.004 0.996 0.000
H21.2 Degeneration of iris and ciliary body
0.004 0.996 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.000 0.996 0.004
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.004 0.996 0.000
Y54.0 Mineralocorticoids
0.004 0.996 0.000
C81.1 Nodular sclerosis
0.003 0.996 0.000
Q21.3 Tetralogy of Fallot
0.004 0.996 0.000
Y49.0 Tricyclic and tetracyclic antidepressants
0.004 0.996 0.000
H15.1 Episcleritis
0.004 0.996 0.000
Y46.2 Hydantoin derivatives
0.004 0.996 0.000
H16.0 Corneal ulcer
0.004 0.996 0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.004 0.996 0.000
G44.1 Vascular headache, not elsewhere classified
0.000 0.996 0.004
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.004 0.996 0.000
Y54.8 Agents affecting uric acid metabolism
0.004 0.996 0.000
H15.9 Disorder of sclera, unspecified
0.004 0.996 0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis
0.004 0.996 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.004 0.996 0.000
Y48.5 Therapeutic gases
0.004 0.996 0.000
Y48.1 Parenteral anaesthetics
0.004 0.996 0.000
Y48.0 Inhaled anaesthetics
0.004 0.996 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.004 0.996 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.004 0.996 0.000
R44.0 Auditory hallucinations
0.004 0.996 0.000
Y54.7 Agents affecting calcification
0.004 0.996 0.000
R44.2 Other hallucinations
0.004 0.996 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.004 0.996 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.004 0.996 0.000
Y48.4 Anaesthetic, unspecified
0.004 0.996 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.004 0.996 0.000
H21.4 Pupillary membranes
0.003 0.996 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.004 0.996 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.004 0.996 0.000
Q23.4 Hypoplastic left heart syndrome
0.004 0.996 0.000
Q23.2 Congenital mitral stenosis
0.004 0.996 0.000
H15.8 Other disorders of sclera
0.003 0.996 0.000
Y44.9 Other and unspecified agents affecting blood constituents
0.003 0.996 0.000
Y44.7 Plasma substitutes
0.003 0.996 0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.003 0.996 0.000
H17.9 Corneal scar and opacity, unspecified
0.003 0.996 0.000
I60.8 Other subarachnoid haemorrhage
0.004 0.996 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.003 0.996 0.000
H15.0 Scleritis
0.003 0.996 0.000
H17.1 Other central corneal opacity
0.003 0.996 0.000
H17.0 Adherent leukoma
0.003 0.996 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.004 0.996 0.000
Y42.7 Androgens and anabolic congeners
0.004 0.996 0.000
Y44.6 Natural blood and blood products
0.003 0.996 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.000 0.996 0.003
J15.2 Pneumonia due to staphylococcus
0.003 0.996 0.000
Q25.0 Patent ductus arteriosus
0.003 0.996 0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.003 0.996 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.003 0.997 0.000
Q26 Congenital malformations of great veins
0.003 0.997 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.003 0.997 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.003 0.997 0.000
Q25.3 Stenosis of aorta
0.003 0.997 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.003 0.997 0.000
H20.0 Acute and subacute iridocyclitis
0.003 0.997 0.000
Q25.7 Other congenital malformations of pulmonary artery
0.003 0.997 0.000
Y48.3 Local anaesthetics
0.003 0.997 0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified
0.003 0.997 0.000
M22.8 Other disorders of patella
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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