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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1539808
log Bayes Factor = 0.0106367
Chromosome 18   position 5,978,931  (GRCh37) Explore rs1539808 on Ensembl!
Variant rs1539808 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J47 Bronchiectasis
0.016 0.984 0.000
I30-I52 Other forms of heart disease
0.000 0.985 0.015
I44 Atrioventricular and left bundle-branch block
0.000 0.985 0.015
I50.1 Left ventricular failure
0.000 0.985 0.015
I50 Heart failure
0.000 0.985 0.015
I34 Nonrheumatic mitral valve disorders
0.000 0.985 0.015
I35 Nonrheumatic aortic valve disorders
0.000 0.986 0.014
I35.0 Aortic (valve) stenosis
0.000 0.986 0.014
I34.1 Mitral (valve) prolapse
0.000 0.987 0.013
I51 Complications and ill-defined descriptions of heart disease
0.000 0.987 0.013
I44.2 Atrioventricular block, complete
0.000 0.987 0.013
I44.1 Atrioventricular block, second degree
0.000 0.987 0.013
I44.7 Left bundle-branch block, unspecified
0.000 0.987 0.013
I34.0 Mitral (valve) insufficiency
0.000 0.987 0.013
I50.9 Heart failure, unspecified
0.000 0.987 0.012
Z53.0 Procedure not carried out because of contraindication
0.000 0.988 0.012
I42 Cardiomyopathy
0.000 0.988 0.012
I31 Other diseases of pericardium
0.000 0.988 0.012
I44.0 Atrioventricular block, first degree
0.000 0.988 0.012
I52 Other heart disorders in diseases classified elsewhere
0.000 0.989 0.011
I48 Atrial fibrillation and flutter
0.000 0.989 0.011
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.989 0.011
I41 Myocarditis in diseases classified elsewhere
0.000 0.989 0.011
I40 Acute myocarditis
0.000 0.989 0.011
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.989 0.011
I37 Pulmonary valve disorders
0.000 0.989 0.011
I36 Nonrheumatic tricuspid valve disorders
0.000 0.989 0.011
I33 Acute and subacute endocarditis
0.000 0.989 0.011
I32 Pericarditis in diseases classified elsewhere
0.000 0.989 0.011
I30 Acute pericarditis
0.000 0.989 0.011
I38 Endocarditis, valve unspecified
0.000 0.989 0.011
I44.6 Other and unspecified fascicular block
0.000 0.989 0.011
I44.5 Left posterior fascicular block
0.000 0.989 0.011
I44.4 Left anterior fascicular block
0.000 0.989 0.011
I44.3 Other and unspecified atrioventricular block
0.000 0.989 0.011
I51.8 Other ill-defined heart diseases
0.000 0.989 0.011
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.989 0.011
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.989 0.011
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.989 0.011
I51.7 Cardiomegaly
0.000 0.990 0.010
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.990 0.010
I35.9 Aortic valve disorder, unspecified
0.000 0.990 0.010
I35.8 Other aortic valve disorders
0.000 0.990 0.010
I47 Paroxysmal tachycardia
0.000 0.990 0.010
I49 Other cardiac arrhythmias
0.000 0.990 0.010
I42.9 Cardiomyopathy, unspecified
0.000 0.990 0.010
I31.3 Pericardial effusion (noninflammatory)
0.000 0.990 0.010
Z53.8 Procedure not carried out for other reasons
0.000 0.990 0.010
I51.6 Cardiovascular disease, unspecified
0.000 0.990 0.009
I51.5 Myocardial degeneration
0.000 0.990 0.009
I51.4 Myocarditis, unspecified
0.000 0.990 0.009
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.990 0.009
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.990 0.009
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.990 0.009
I51.0 Cardiac septal defect, acquired
0.000 0.990 0.009
I35.1 Aortic (valve) insufficiency
0.000 0.990 0.009
I45 Other conduction disorders
0.000 0.991 0.009
Z53 Persons encountering health services for specifie procedures, not carried out
0.000 0.991 0.009
I51.9 Heart disease, unspecified
0.000 0.991 0.009
I46 Cardiac arrest
0.000 0.991 0.009
I42.8 Other cardiomyopathies
0.000 0.991 0.009
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.991 0.009
I42.6 Alcoholic cardiomyopathy
0.000 0.991 0.009
I42.5 Other restrictive cardiomyopathy
0.000 0.991 0.009
I42.4 Endocardial fibroelastosis
0.000 0.991 0.009
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.991 0.009
I42.2 Other hypertrophic cardiomyopathy
0.000 0.991 0.009
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.991 0.009
I31.8 Other specified diseases of pericardium
0.000 0.991 0.009
I31.2 Haemopericardium, not elsewhere classified
0.000 0.991 0.009
I31.1 Chronic constrictive pericarditis
0.000 0.991 0.009
I31.0 Chronic adhesive pericarditis
0.000 0.991 0.009
I42.0 Dilated cardiomyopathy
0.000 0.991 0.009
I47.2 Ventricular tachycardia
0.000 0.991 0.009
I49.5 Sick sinus syndrome
0.000 0.992 0.008
I30.9 Acute pericarditis, unspecified
0.000 0.992 0.008
I30.8 Other forms of acute pericarditis
0.000 0.992 0.008
I30.1 Infective pericarditis
0.000 0.992 0.008
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.992 0.008
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.992 0.008
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.992 0.008
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.992 0.008
I33.9 Acute endocarditis, unspecified
0.000 0.992 0.008
I33.0 Acute and subacute infective endocarditis
0.000 0.992 0.008
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.992 0.008
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.992 0.008
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.992 0.008
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.992 0.008
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.992 0.008
I37.9 Pulmonary valve disorder, unspecified
0.000 0.992 0.008
I37.8 Other pulmonary valve disorders
0.000 0.992 0.008
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.992 0.008
I37.1 Pulmonary valve insufficiency
0.000 0.992 0.008
I37.0 Pulmonary valve stenosis
0.000 0.992 0.008
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.992 0.008
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.992 0.008
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.992 0.008
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.992 0.008
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.992 0.008
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.992 0.008
I40.9 Acute myocarditis, unspecified
0.000 0.992 0.008
I40.8 Other acute myocarditis
0.000 0.992 0.008
I40.1 Isolated myocarditis
0.000 0.992 0.008
I40.0 Infective myocarditis
0.000 0.992 0.008
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.992 0.008
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.992 0.008
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.992 0.008
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.992 0.008
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.992 0.008
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.992 0.008
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.992 0.008
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.992 0.008
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.992 0.008
I48.4 Atypical atrial flutter
0.000 0.992 0.008
I48.3 Typical atrial flutter
0.000 0.992 0.008
I48.2 Chronic atrial fibrillation
0.000 0.992 0.008
I48.1 Persistent atrial fibrillation
0.000 0.992 0.008
I48.0 Paroxysmal atrial fibrillation
0.000 0.992 0.008
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.992 0.008
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.992 0.008
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.992 0.008
I49.3 Ventricular premature depolarisation
0.000 0.992 0.008
I84.9 Unspecified haemorrhoids without complication
0.000 0.992 0.008
I47.0 Reentry ventricular arrhythmia
0.000 0.992 0.008
I31.9 Disease of pericardium, unspecified
0.000 0.992 0.007
I49.2 Junctional premature depolarisation
0.000 0.992 0.007
I49.1 Atrial premature depolarisation
0.000 0.992 0.007
J40-J47 Chronic lower respiratory diseases
0.008 0.992 0.000
I49.8 Other specified cardiac arrhythmias
0.000 0.993 0.007
I49.4 Other and unspecified premature depolarisation
0.000 0.993 0.007
I50.0 Congestive heart failure
0.000 0.993 0.007
I45.9 Conduction disorder, unspecified
0.000 0.993 0.007
I45.8 Other specified conduction disorders
0.000 0.993 0.007
I45.5 Other specified heart block
0.000 0.993 0.007
I45.4 Nonspecific intraventricular block
0.000 0.993 0.007
I45.3 Trifascicular block
0.000 0.993 0.007
I45.2 Bifascicular block
0.000 0.993 0.007
I45.0 Right fascicular block
0.000 0.993 0.007
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.000 0.993 0.007
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.007 0.993 0.000
Z53.9 Procedure not carried out, unspecified reason
0.000 0.993 0.007
I46.1 Sudden cardiac death, so described
0.000 0.993 0.007
I45.1 Other and unspecified right bundle-branch block
0.000 0.993 0.007
I47.1 Supraventricular tachycardia
0.000 0.993 0.007
J44 Other chronic obstructive pulmonary disease
0.007 0.993 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.000 0.993 0.006
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.994 0.006
I49.0 Ventricular fibrillation and flutter
0.000 0.994 0.006
I46.9 Cardiac arrest, unspecified
0.000 0.994 0.006
J42 Unspecified chronic bronchitis
0.006 0.994 0.000
I49.9 Cardiac arrhythmia, unspecified
0.000 0.994 0.006
J41 Simple and mucopurulent chronic bronchitis
0.006 0.994 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.006 0.994 0.000
I45.6 Preexcitation syndrome
0.000 0.994 0.005
J43 Emphysema
0.005 0.994 0.000
I46.0 Cardiac arrest with successful resuscitation
0.000 0.995 0.005
J46 Status asthmaticus
0.005 0.995 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.005 0.995 0.000
J45 Asthma
0.005 0.995 0.000
J40 Bronchitis, not specified as acute or chronic
0.005 0.995 0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.004 0.996 0.000
J41.1 Mucopurulent chronic bronchitis
0.004 0.996 0.000
J41.0 Simple chronic bronchitis
0.004 0.996 0.000
J45.0 Predominantly allergic asthma
0.004 0.996 0.000
J43.8 Other emphysema
0.004 0.996 0.000
J43.2 Centrilobular emphysema
0.004 0.996 0.000
J43.1 Panlobular emphysema
0.004 0.996 0.000
J43.0 MacLeod's syndrome
0.004 0.996 0.000
J43.9 Emphysema, unspecified
0.004 0.996 0.000
I73.9 Peripheral vascular disease, unspecified
0.000 0.996 0.004
I77.1 Stricture of artery
0.000 0.996 0.004
J45.8 Mixed asthma
0.004 0.996 0.000
J45.1 Nonallergic asthma
0.004 0.996 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.996 0.004
I77 Other disorders of arteries and arterioles
0.000 0.996 0.004
I73 Other peripheral vascular diseases
0.000 0.996 0.004
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.996 0.004
I74 Arterial embolism and thrombosis
0.000 0.996 0.003
M16.9 Coxarthrosis, unspecified
0.003 0.997 0.000
M54.56 Low back pain (Lumbar region)
0.000 0.997 0.003
K51.9 Ulcerative colitis, unspecified
0.003 0.997 0.000
I78 Diseases of capillaries
0.000 0.997 0.003
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.997 0.003
I77.8 Other specified disorders of arteries and arterioles
0.000 0.997 0.003
I77.6 Arteritis, unspecified
0.000 0.997 0.003
I77.5 Necrosis of artery
0.000 0.997 0.003
I77.4 Coeliac artery compression syndrome
0.000 0.997 0.003
I77.3 Arterial fibromuscular dysplasia
0.000 0.997 0.003
I77.2 Rupture of artery
0.000 0.997 0.003
I77.0 Arteriovenous fistula, acquired
0.000 0.997 0.003
I73.8 Other specified peripheral vascular diseases
0.000 0.997 0.003
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.997 0.003
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.997 0.003
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.997 0.003
I74.8 Embolism and thrombosis of other arteries
0.000 0.997 0.003
I74.5 Embolism and thrombosis of iliac artery
0.000 0.997 0.003
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.997 0.003
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.997 0.003
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.997 0.003
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.997 0.003
Chapter IX Diseases of the circulatory system
0.000 0.997 0.003
I84 Haemorrhoids
0.000 0.997 0.003
I70 Atherosclerosis
0.000 0.997 0.003
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.997 0.002
I84.8 Unspecified haemorrhoids with other complications
0.000 0.997 0.003
I72 Other aneurysm
0.000 0.997 0.002
I73.0 Raynaud's syndrome
0.000 0.997 0.002
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.998 0.002
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.998 0.002
I78.1 Naevus, nonneoplastic
0.000 0.998 0.002
I26 Pulmonary embolism
0.000 0.998 0.002
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.998 0.002
I71 Aortic aneurysm and dissection
0.000 0.998 0.002
I78.9 Disease of capillaries, unspecified
0.000 0.998 0.002
I78.8 Other diseases of capillaries
0.000 0.998 0.002
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.998 0.002
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.998 0.002
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.998 0.002
I79.1 Aortitis in diseases classified elsewhere
0.000 0.998 0.002
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.998 0.002
I80 Phlebitis and thrombophlebitis
0.000 0.998 0.002
I00-I02 Acute rheumatic fever
0.000 0.998 0.002
I84.4 External haemorrhoids with other complications
0.000 0.998 0.002
I84.0 Internal thrombosed haemorrhoids
0.000 0.998 0.002
I85 Oesophageal varices
0.000 0.998 0.002
K51 Ulcerative colitis
0.002 0.998 0.000
N18.9 Chronic renal failure, unspecified
0.000 0.998 0.002
I70.9 Generalised and unspecified atherosclerosis
0.000 0.998 0.002
I70.8 Atherosclerosis of other arteries
0.000 0.998 0.002
I70.1 Atherosclerosis of renal artery
0.000 0.998 0.002
I70.0 Atherosclerosis of aorta
0.000 0.998 0.002
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.998 0.002
I84.3 External thrombosed haemorrhoids
0.000 0.998 0.002
L40.9 Psoriasis, unspecified
0.000 0.998 0.002
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.002 0.998 0.000
I84.5 External haemorrhoids without complication
0.000 0.998 0.002
I88 Nonspecific lymphadenitis
0.000 0.998 0.002
I87 Other disorders of veins
0.000 0.998 0.002
I86 Varicose veins of other sites
0.000 0.998 0.002
I81 Portal vein thrombosis
0.000 0.998 0.002
S52.10 Fracture of upper end of radius (closed)
0.002 0.998 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.000 0.998 0.002
K51.4 Pseudopolyposis of colon
0.002 0.998 0.000
I72.9 Aneurysm of unspecified site
0.000 0.998 0.002
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.998 0.002
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.998 0.002
I72.4 Aneurysm of artery of lower extremity
0.000 0.998 0.002
I72.3 Aneurysm of iliac artery
0.000 0.998 0.002
I72.2 Aneurysm of renal artery
0.000 0.998 0.002
I72.1 Aneurysm of artery of upper extremity
0.000 0.998 0.002
I72.0 Aneurysm of carotid artery
0.000 0.998 0.002
K91.3 Postoperative intestinal obstruction
0.002 0.998 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.998 0.002
I28 Other diseases of pulmonary vessels
0.000 0.998 0.002
I05-I09 Chronic rheumatic heart diseases
0.000 0.998 0.002
D64.9 Anaemia, unspecified
0.000 0.998 0.002
K51.3 Ulcerative (chronic) rectosigmoiditis
0.002 0.998 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.998 0.002
M16 Coxarthrosis [arthrosis of hip]
0.002 0.998 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.998 0.002
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.998 0.002
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.998 0.002
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.998 0.002
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.998 0.002
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.998 0.002
I71.0 Dissection of aorta [any part]
0.000 0.998 0.002
C44.3 Skin of other and unspecified parts of face
0.000 0.998 0.002
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.002 0.998 0.000
I85.9 Oesophageal varices without bleeding
0.000 0.998 0.002
I82 Other venous embolism and thrombosis
0.000 0.998 0.002
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.998 0.002
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.998 0.002
I83 Varicose veins of lower extremities
0.001 0.998 0.001
I02 Rheumatic chorea
0.000 0.998 0.002
I01 Rheumatic fever with heart involvement
0.000 0.998 0.002
I00 Rheumatic fever without mention of heart involvement
0.000 0.998 0.002
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.998 0.002
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.998 0.002
I89.0 Lymphoedema, not elsewhere classified
0.000 0.998 0.002
H40.1 Primary open-angle glaucoma
0.000 0.998 0.002
I85.0 Oesophageal varices with bleeding
0.000 0.998 0.002
K51.8 Other ulcerative colitis
0.002 0.998 0.000
K51.5 Mucosal proctocolitis
0.002 0.998 0.000
K51.2 Ulcerative (chronic) proctitis
0.002 0.998 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.002 0.998 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.002 0.998 0.000
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.998 0.002
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.998 0.002
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.998 0.002
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.998 0.002
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.998 0.002
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.998 0.002
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.998 0.002
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.998 0.002
H26.4 After-cataract
0.000 0.998 0.002
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.998 0.002
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.998 0.002
I89.1 Lymphangitis
0.000 0.998 0.002
F10.1 Harmful use
0.000 0.998 0.002
I72.8 Aneurysm of other specified arteries
0.001 0.998 0.001
I86.8 Varicose veins of other specified sites
0.000 0.998 0.002
I86.4 Gastric varices
0.000 0.998 0.002
I86.3 Vulval varices
0.000 0.998 0.002
I86.2 Pelvic varices
0.000 0.998 0.002
I86.1 Scrotal varices
0.000 0.998 0.002
I86.0 Sublingual varices
0.000 0.998 0.002
I87.9 Disorder of vein, unspecified
0.000 0.998 0.002
I87.8 Other specified disorders of veins
0.000 0.998 0.002
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.998 0.002
I87.1 Compression of vein
0.000 0.998 0.002
I87.0 Postphlebitic syndrome
0.000 0.998 0.002
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.998 0.002
I88.8 Other nonspecific lymphadenitis
0.000 0.998 0.002
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.998 0.002
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.998 0.002
M16.0 Primary coxarthrosis, bilateral
0.002 0.998 0.000
I27 Other pulmonary heart diseases
0.000 0.998 0.002
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.998 0.001
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.000 0.998 0.002
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.000 0.998 0.002
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.998 0.001
I07 Rheumatic tricuspid valve diseases
0.000 0.998 0.002
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.998 0.001
I28.8 Other specified diseases of pulmonary vessels
0.000 0.998 0.001
I28.1 Aneurysm of pulmonary artery
0.000 0.998 0.001
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.998 0.001
I09 Other rheumatic heart diseases
0.000 0.998 0.002
I06 Rheumatic aortic valve diseases
0.000 0.998 0.002
I05 Rheumatic mitral valve diseases
0.000 0.998 0.002
M16.7 Other secondary coxarthrosis
0.002 0.998 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.002 0.998 0.000
M16.5 Other posttraumatic coxarthrosis
0.002 0.998 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.002 0.998 0.000
M16.3 Other dysplastic coxarthrosis
0.002 0.998 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.002 0.998 0.000
M54.5 Low back pain
0.000 0.998 0.002
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.998 0.001
I82.3 Embolism and thrombosis of renal vein
0.000 0.998 0.001
I82.2 Embolism and thrombosis of vena cava
0.000 0.998 0.001
I82.1 Thrombophlebitis migrans
0.000 0.998 0.001
I82.0 Budd-Chiari syndrome
0.000 0.998 0.001
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.001 0.998 0.001
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.002 0.998 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.998 0.001
I01.8 Other acute rheumatic heart disease
0.000 0.998 0.001
I01.2 Acute rheumatic myocarditis
0.000 0.998 0.001
I01.1 Acute rheumatic endocarditis
0.000 0.998 0.001
I01.0 Acute rheumatic pericarditis
0.000 0.998 0.001
I02.9 Rheumatic chorea without heart involvement
0.000 0.998 0.001
I02.0 Rheumatic chorea with heart involvement
0.000 0.998 0.001
T39.1 4-Aminophenol derivatives
0.000 0.998 0.002
I83.0 Varicose veins of lower extremities with ulcer
0.001 0.998 0.001
M16.1 Other primary coxarthrosis
0.002 0.998 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.998 0.001
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.998 0.001
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.998 0.001
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.001 0.998 0.001
I83.1 Varicose veins of lower extremities with inflammation
0.001 0.998 0.001
I27.8 Other specified pulmonary heart diseases
0.000 0.998 0.001
I27.1 Kyphoscoliotic heart disease
0.000 0.998 0.001
N18 Chronic renal failure
0.000 0.998 0.002
I27.2 Other secondary pulmonary hypertension
0.000 0.998 0.001
Y83.8 Other surgical procedures
0.000 0.998 0.002
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.002 0.998 0.000
I07.1 Tricuspid insufficiency
0.000 0.998 0.001
I07.9 Tricuspid valve disease, unspecified
0.000 0.998 0.001
I07.8 Other tricuspid valve diseases
0.000 0.998 0.001
I07.2 Tricuspid stenosis with insufficiency
0.000 0.998 0.001
I07.0 Tricuspid stenosis
0.000 0.998 0.001
J69.0 Pneumonitis due to food and vomit
0.001 0.998 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.001 0.998 0.000
N18.5 Chronic kidney disease, stage 5
0.000 0.998 0.001
I05.9 Mitral valve disease, unspecified
0.000 0.998 0.001
I05.8 Other mitral valve diseases
0.000 0.998 0.001
I05.2 Mitral stenosis with insufficiency
0.000 0.998 0.001
I05.1 Rheumatic mitral insufficiency
0.000 0.998 0.001
I05.0 Mitral stenosis
0.000 0.998 0.001
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.998 0.001
I06.8 Other rheumatic aortic valve diseases
0.000 0.998 0.001
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.998 0.001
I06.1 Rheumatic aortic insufficiency
0.000 0.998 0.001
I06.0 Rheumatic aortic stenosis
0.000 0.998 0.001
I09.9 Rheumatic heart disease, unspecified
0.000 0.998 0.001
I09.8 Other specified rheumatic heart diseases
0.000 0.998 0.001
I09.2 Chronic rheumatic pericarditis
0.000 0.998 0.001
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.998 0.001
I09.0 Rheumatic myocarditis
0.000 0.998 0.001
I82.8 Embolism and thrombosis of other specified veins
0.001 0.998 0.001
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.000 0.998 0.001
I27.0 Primary pulmonary hypertension
0.000 0.998 0.001
K02.9 Dental caries, unspecified
0.001 0.998 0.000
M54.55 Low back pain (Thoracolumbar region)
0.000 0.998 0.001
M54.54 Low back pain-Thoracic
0.000 0.998 0.001
M54.53 Low back pain-Cervicothoracic
0.000 0.998 0.001
M54.52 Low back pain-Cervical
0.000 0.998 0.001
M54.51 Low back pain-Occipit-atl-axl
0.000 0.998 0.001
M54.50 Low back pain (Multiple sites in spine)
0.000 0.998 0.001
I84.6 Residual haemorrhoidal skin tags
0.000 0.998 0.001
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.001 0.998 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.999 0.001
I27.9 Pulmonary heart disease, unspecified
0.000 0.999 0.001
N43.3 Hydrocele, unspecified
0.001 0.999 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.001 0.999 0.000
H40 Glaucoma
0.000 0.999 0.001
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.999 0.001
I99 Other and unspecified disorders of circulatory system
0.000 0.999 0.001
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.999 0.001
D73.0 Hyposplenism
0.001 0.999 0.000
N18.8 Other chronic renal failure
0.000 0.999 0.001
N18.2 Chronic kidney disease, stage 2
0.000 0.999 0.001
N18.1 Chronic kidney disease, stage 1
0.000 0.999 0.001
N18.0 End-stage renal disease
0.000 0.999 0.001
F10.0 Acute intoxication
0.000 0.999 0.001
H25.0 Senile incipient cataract
0.000 0.999 0.001
H40.2 Primary angle-closure glaucoma
0.000 0.999 0.001
L98.7 Excessive and redundant skin and subcutaneous tissue
0.001 0.999 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.001 0.999 0.000
L98.5 Mucinosis of skin
0.001 0.999 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.001 0.999 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.001 0.999 0.000
L98.1 Factitial dermatitis
0.001 0.999 0.000
R59.0 Localised enlarged lymph nodes
0.001 0.999 0.000
I08 Multiple valve diseases
0.000 0.999 0.001
I12.0 Hypertensive renal disease with renal failure
0.000 0.999 0.001
K60.2 Anal fissure, unspecified
0.000 0.999 0.001
L98.0 Pyogenic granuloma
0.001 0.999 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.001 0.999 0.000
S52.1 Fracture of upper end of radius
0.001 0.999 0.000
I12 Hypertensive renal disease
0.000 0.999 0.001
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.999 0.001
J69 Pneumonitis due to solids and liquids
0.001 0.999 0.000
M54.59 Low back pain (Site unspecified)
0.000 0.999 0.001
H40.0 Glaucoma suspect
0.000 0.999 0.001
K91.4 Colostomy and enterostomy malfunction
0.001 0.999 0.000
I10-I15 Hypertensive diseases
0.000 0.999 0.001
F41.2 Mixed anxiety and depressive disorder
0.000 0.999 0.001
N18.3 Chronic kidney disease, stage 3
0.000 0.999 0.001
M43.16 Spondylolisthesis (Lumbar region)
0.001 0.999 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.001 0.999 0.000
K91.5 Postcholecystectomy syndrome
0.001 0.999 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.001 0.999 0.000
K91.1 Postgastric surgery syndromes
0.001 0.999 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.001 0.999 0.000
F10.2 Dependence syndrome
0.000 0.999 0.001
H40.8 Other glaucoma
0.000 0.999 0.001
H40.6 Glaucoma secondary to drugs
0.000 0.999 0.001
H40.5 Glaucoma secondary to other eye disorders
0.000 0.999 0.001
H40.4 Glaucoma secondary to eye inflammation
0.000 0.999 0.001
H40.3 Glaucoma secondary to eye trauma
0.000 0.999 0.001
H53.0 Amblyopia ex anopsia
0.001 0.999 0.000
N18.4 Chronic kidney disease, stage 4
0.000 0.999 0.001
S80.9 Superficial injury of lower leg, unspecified
0.001 0.999 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.999 0.001
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.999 0.001
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.999 0.001
I97.1 Other functional disturbances following cardiac surgery
0.000 0.999 0.001
I97.0 Postcardiotomy syndrome
0.000 0.999 0.001
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.999 0.001
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.999 0.001
T39.4 Antirheumatics, not elsewhere classified
0.000 0.999 0.001
T39.2 Pyrazolone derivatives
0.000 0.999 0.001
T39.0 Salicylates
0.000 0.999 0.001
D64 Other anaemias
0.000 0.999 0.001
H53.2 Diplopia
0.001 0.999 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.999 0.001
F10 Mental and behavioural disorders due to use of alcohol
0.000 0.999 0.001
J81 Pulmonary oedema
0.001 0.999 0.000
S52.11 Fracture of upper end of radius (open)
0.001 0.999 0.000
I08.9 Multiple valve disease, unspecified
0.000 0.999 0.001
I08.8 Other multiple valve diseases
0.000 0.999 0.001
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.999 0.001
J44.9 Chronic obstructive pulmonary disease, unspecified
0.001 0.999 0.000
J69.8 Pneumonitis due to other solids and liquids
0.001 0.999 0.000
J69.1 Pneumonitis due to oils and essences
0.001 0.999 0.000
K35.9 Acute appendicitis, unspecified
0.000 0.999 0.001
T43.2 Other and unspecified antidepressants
0.000 0.999 0.001
I12.9 Hypertensive renal disease without renal failure
0.000 0.999 0.001
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.999 0.001
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.999 0.001
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.999 0.001
I98.0 Cardiovascular syphilis
0.000 0.999 0.001
I15 Secondary hypertension
0.000 0.999 0.001
I13 Hypertensive heart and renal disease
0.000 0.999 0.001
J60-J70 Lung diseases due to external agents
0.001 0.999 0.000
M54.57 Low back pain (Lumbosacral region)
0.000 0.999 0.001
G47.9 Sleep disorder, unspecified
0.000 0.999 0.001
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.999 0.001
D64.8 Other specified anaemias
0.000 0.999 0.001
D64.4 Congenital dyserythropoietic anaemia
0.000 0.999 0.001
D64.3 Other sideroblastic anaemias
0.000 0.999 0.001
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.999 0.001
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.999 0.001
D64.0 Hereditary sideroblastic anaemia
0.000 0.999 0.001
F10.9 Unspecified mental and behavioural disorder
0.000 0.999 0.001
F10.8 Other mental and behavioural disorders
0.000 0.999 0.001
F10.7 Residual and late-onset psychotic disorder
0.000 0.999 0.001
F10.6 Amnesic syndrome
0.000 0.999 0.001
F10.5 Psychotic disorder
0.000 0.999 0.001
F10.4 Withdrawal state with delirium
0.000 0.999 0.001
H40.9 Glaucoma, unspecified
0.000 0.999 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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