TreeWAS – Variant ID: rs1552244

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z83.5 Family history of eye and ear disorders	0.057	0.943	0.000
I77.1 Stricture of artery	0.024	0.976	0.000
I71 Aortic aneurysm and dissection	0.022	0.978	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.022	0.978	0.000
I72 Other aneurysm	0.022	0.978	0.000
I72.4 Aneurysm of artery of lower extremity	0.022	0.978	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.021	0.979	0.000
I74 Arterial embolism and thrombosis	0.021	0.979	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.020	0.980	0.000
I77 Other disorders of arteries and arterioles	0.020	0.980	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.019	0.981	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.019	0.981	0.000
Q61 Cystic kidney disease	0.019	0.981	0.000
I72.8 Aneurysm of other specified arteries	0.018	0.982	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.018	0.982	0.000
I70 Atherosclerosis	0.018	0.982	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.018	0.982	0.000
Q60-Q64 Congenital malformations of the urinary system	0.018	0.982	0.000
Q12.0 Congenital cataract	0.017	0.983	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.017	0.983	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.017	0.983	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.017	0.983	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.017	0.983	0.000
Q61.3 Polycystic kidney, unspecified	0.017	0.983	0.000
I74.5 Embolism and thrombosis of iliac artery	0.017	0.983	0.000
Q12 Congenital lens malformations	0.016	0.983	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.016	0.983	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.016	0.984	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.016	0.984	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.016	0.984	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.016	0.984	0.000
R60.9 Oedema, unspecified	0.016	0.984	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.016	0.984	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.016	0.984	0.000
Q61.5 Medullary cystic kidney	0.016	0.984	0.000
Q61.0 Congenital single renal cyst	0.016	0.984	0.000
I72.0 Aneurysm of carotid artery	0.016	0.984	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.016	0.984	0.000
O03.4 Incomplete, without complication	0.016	0.984	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.016	0.984	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.016	0.984	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.016	0.984	0.000
I72.1 Aneurysm of artery of upper extremity	0.016	0.984	0.000
I74.8 Embolism and thrombosis of other arteries	0.016	0.984	0.000
O03 Spontaneous abortion	0.016	0.984	0.000
Z95.0 Presence of cardiac pacemaker	0.015	0.985	0.000
O03.9 Complete or unspecified, without complication	0.015	0.985	0.000
Q76 Congenital malformations of spine and bony thorax	0.015	0.985	0.000
I72.2 Aneurysm of renal artery	0.015	0.985	0.000
I71.0 Dissection of aorta [any part]	0.015	0.985	0.000
I79.1 Aortitis in diseases classified elsewhere	0.015	0.985	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.015	0.985	0.000
Q61.2 Polycystic kidney, adult type	0.015	0.985	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.015	0.985	0.000
R60.0 Localised oedema	0.015	0.985	0.000
R60 Oedema, not elsewhere classified	0.015	0.985	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.015	0.985	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.014	0.985	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.015	0.985	0.000
I72.3 Aneurysm of iliac artery	0.014	0.986	0.000
I77.5 Necrosis of artery	0.014	0.986	0.000
I77.4 Coeliac artery compression syndrome	0.014	0.986	0.000
I77.3 Arterial fibromuscular dysplasia	0.014	0.986	0.000
I70.0 Atherosclerosis of aorta	0.014	0.986	0.000
Q43 Other congenital malformations of intestine	0.014	0.986	0.000
I72.9 Aneurysm of unspecified site	0.014	0.986	0.000
I70.1 Atherosclerosis of renal artery	0.014	0.986	0.000
I77.6 Arteritis, unspecified	0.014	0.986	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.014	0.986	0.000
Q64 Other congenital malformations of urinary system	0.014	0.986	0.000
Q61.9 Cystic kidney disease, unspecified	0.013	0.986	0.000
Q61.8 Other cystic kidney diseases	0.013	0.986	0.000
Q61.4 Renal dysplasia	0.013	0.986	0.000
Q61.1 Polycystic kidney, infantile type	0.013	0.986	0.000
Z83 Family history of other specific disorders	0.014	0.986	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.013	0.986	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.013	0.987	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.013	0.987	0.000
I77.2 Rupture of artery	0.013	0.987	0.000
I70.9 Generalised and unspecified atherosclerosis	0.013	0.987	0.000
I70.8 Atherosclerosis of other arteries	0.013	0.987	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.013	0.987	0.000
Q65 Congenital deformities of hip	0.013	0.987	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.013	0.987	0.000
R60.1 Generalised oedema	0.013	0.987	0.000
Q24 Other congenital malformations of heart	0.013	0.987	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.013	0.987	0.000
I77.0 Arteriovenous fistula, acquired	0.012	0.987	0.000
Z83.3 Family history of diabetes mellitus	0.013	0.987	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.012	0.988	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.012	0.988	0.000
Q35-Q37 Cleft lip and cleft palate	0.012	0.988	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.012	0.988	0.000
Q63 Other congenital malformations of kidney	0.012	0.988	0.000
Q12.9 Congenital lens malformation, unspecified	0.012	0.988	0.000
Q12.8 Other congenital lens malformations	0.012	0.988	0.000
Q12.4 Spherophakia	0.012	0.988	0.000
Q12.3 Congenital aphakia	0.012	0.988	0.000
Q12.2 Coloboma of lens	0.012	0.988	0.000
Q12.1 Congenital displaced lens	0.012	0.988	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.012	0.988	0.000
Q24.8 Other specified congenital malformations of heart	0.012	0.988	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.012	0.988	0.000
Q15 Other congenital malformations of eye	0.012	0.988	0.000
Q14 Congenital malformations of posterior segment of eye	0.012	0.988	0.000
Q13 Congenital malformations of anterior segment of eye	0.012	0.988	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.012	0.988	0.000
Q17 Other congenital malformations of ear	0.012	0.988	0.000
Q50-Q56 Congenital malformations of genital organs	0.012	0.988	0.000
I78 Diseases of capillaries	0.012	0.988	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.012	0.988	0.000
Q75 Other congenital malformations of skull and face bones	0.012	0.988	0.000
Q73 Reduction defects of unspecified limb	0.012	0.988	0.000
Q72 Reduction defects of lower limb	0.012	0.988	0.000
Q71 Reduction defects of upper limb	0.012	0.988	0.000
Q70 Syndactyly	0.012	0.988	0.000
Q69 Polydactyly	0.012	0.988	0.000
Q68 Other congenital musculoskeletal deformities	0.012	0.988	0.000
Q78 Other osteochondrodysplasias	0.011	0.988	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.011	0.988	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.011	0.989	0.000
O03.7 Complete or unspecified, complicated by embolism	0.011	0.989	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.011	0.989	0.000
O03.3 Incomplete, with other and unspecified complications	0.011	0.989	0.000
O03.2 Incomplete, complicated by embolism	0.011	0.989	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.011	0.989	0.000
Q74 Other congenital malformations of limb(s)	0.011	0.989	0.000
Q76.0 Spina bifida occulta	0.011	0.989	0.000
Q43.1 Hirschsprung's disease	0.011	0.989	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.011	0.989	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.011	0.989	0.000
Q76.8 Other congenital malformations of bony thorax	0.011	0.989	0.000
Q76.7 Congenital malformation of sternum	0.011	0.989	0.000
Q76.6 Other congenital malformations of ribs	0.011	0.989	0.000
Q76.5 Cervical rib	0.011	0.989	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.011	0.989	0.000
Q76.2 Congenital spondylolisthesis	0.011	0.989	0.000
Q76.1 Klippel-Feil syndrome	0.011	0.989	0.000
Q00-Q07 Congenital malformations of the nervous system	0.011	0.989	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.011	0.989	0.000
Q43.8 Other specified congenital malformations of intestine	0.011	0.989	0.000
Q65.8 Other congenital deformities of hip	0.011	0.989	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.011	0.989	0.000
Q45 Other congenital malformations of digestive system	0.011	0.989	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.011	0.989	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.011	0.989	0.000
Q11.1 Other anophthalmos	0.011	0.989	0.000
Q43.3 Congenital malformations of intestinal fixation	0.011	0.989	0.000
Q66 Congenital deformities of feet	0.011	0.989	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.011	0.989	0.000
Q60.2 Renal agenesis, unspecified	0.011	0.989	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.011	0.989	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.011	0.989	0.000
Q40 Other congenital malformations of upper alimentary tract	0.011	0.989	0.000
Q43.0 Meckel's diverticulum	0.011	0.989	0.000
Q25 Congenital malformations of great arteries	0.011	0.989	0.000
Q63.2 Ectopic kidney	0.010	0.989	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.010	0.989	0.000
Q39 Congenital malformations of oesophagus	0.010	0.990	0.000
Q96 Turner's syndrome	0.010	0.990	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.010	0.990	0.000
Q52 Other congenital malformations of female genitalia	0.010	0.990	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.010	0.990	0.000
Q43.7 Persistent cloaca	0.010	0.990	0.000
Q43.6 Congenital fistula of rectum and anus	0.010	0.990	0.000
Q43.5 Ectopic anus	0.010	0.990	0.000
Q43.4 Duplication of intestine	0.010	0.990	0.000
Q43.2 Other congenital functional disorders of colon	0.010	0.990	0.000
Q24.5 Malformation of coronary vessels	0.010	0.990	0.000
Q80-Q89 Other congenital malformations	0.010	0.990	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.010	0.990	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.010	0.990	0.000
Q64.8 Other specified congenital malformations of urinary system	0.010	0.990	0.000
Q64.6 Congenital diverticulum of bladder	0.010	0.990	0.000
Q64.5 Congenital absence of bladder and urethra	0.010	0.990	0.000
Q64.4 Malformation of urachus	0.010	0.990	0.000
Q64.2 Congenital posterior urethral valves	0.010	0.990	0.000
Q64.1 Exstrophy of urinary bladder	0.010	0.990	0.000
Q64.0 Epispadias	0.010	0.990	0.000
Z83.6 Family history of diseases of the respiratory system	0.010	0.990	0.000
Z83.0 Family history of human immunodeficiency virus [HIV]	0.010	0.990	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.010	0.990	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.010	0.990	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.010	0.990	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.010	0.990	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.010	0.990	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.010	0.990	0.000
Q90 Down's syndrome	0.010	0.990	0.000
Q26 Congenital malformations of great veins	0.010	0.990	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.010	0.990	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.010	0.990	0.000
O00-O08 Pregnancy with abortive outcome	0.010	0.990	0.000
Q60.6 Potter's syndrome	0.010	0.990	0.000
Q60.5 Renal hypoplasia, unspecified	0.010	0.990	0.000
Q60.4 Renal hypoplasia, bilateral	0.010	0.990	0.000
Q60.3 Renal hypoplasia, unilateral	0.010	0.990	0.000
Q60.1 Renal agenesis, bilateral	0.010	0.990	0.000
Q79.6 Ehlers-Danlos syndrome	0.010	0.990	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.010	0.990	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.009	0.990	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.009	0.990	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.009	0.990	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.009	0.990	0.000
Q11.3 Macrophthalmos	0.009	0.990	0.000
Q11.2 Microphthalmos	0.009	0.990	0.000
Q11.0 Cystic eyeball	0.009	0.990	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.009	0.990	0.000
Q65.9 Congenital deformity of hip, unspecified	0.009	0.990	0.000
Q65.6 Unstable hip	0.009	0.990	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.009	0.990	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.009	0.990	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.009	0.990	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.009	0.990	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.009	0.990	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.009	0.990	0.000
Q23 Congenital malformations of aortic and mitral valves	0.009	0.990	0.000
Q24.6 Congenital heart block	0.009	0.990	0.000
Q24.4 Congenital subaortic stenosis	0.009	0.990	0.000
Q24.3 Pulmonary infundibular stenosis	0.009	0.990	0.000
Q24.2 Cor triatriatum	0.009	0.990	0.000
Q24.1 Levocardia	0.009	0.990	0.000
Q24.0 Dextrocardia	0.009	0.990	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.009	0.991	0.000
Q62.8 Other congenital malformations of ureter	0.009	0.991	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.009	0.991	0.000
Q62.6 Malposition of ureter	0.009	0.991	0.000
Q62.4 Agenesis of ureter	0.009	0.991	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.009	0.991	0.000
Q62.2 Congenital megaloureter	0.009	0.991	0.000
Q62.1 Atresia and stenosis of ureter	0.009	0.991	0.000
Q62.0 Congenital hydronephrosis	0.009	0.991	0.000
Q60.0 Renal agenesis, unilateral	0.009	0.991	0.000
Q52.5 Fusion of labia	0.009	0.991	0.000
Q28 Other congenital malformations of circulatory system	0.009	0.991	0.000
Q62.5 Duplication of ureter	0.009	0.991	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.009	0.991	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.009	0.991	0.000
Q79.5 Other congenital malformations of abdominal wall	0.009	0.991	0.000
Q79.4 Prune belly syndrome	0.009	0.991	0.000
Q79.3 Gastroschisis	0.009	0.991	0.000
Q79.2 Exomphalos	0.009	0.991	0.000
Q79.1 Other congenital malformations of diaphragm	0.009	0.991	0.000
Q79.0 Congenital diaphragmatic hernia	0.009	0.991	0.000
Q34 Other congenital malformations of respiratory system	0.009	0.991	0.000
Q33 Congenital malformations of lung	0.009	0.991	0.000
Q32 Congenital malformations of trachea and bronchus	0.009	0.991	0.000
Q31 Congenital malformations of larynx	0.009	0.991	0.000
Q30 Congenital malformations of nose	0.009	0.991	0.000
Q37 Cleft palate with cleft lip	0.009	0.991	0.000
Q36 Cleft lip	0.009	0.991	0.000
Q35 Cleft palate	0.009	0.991	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.009	0.991	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.009	0.991	0.000
Q63.8 Other specified congenital malformations of kidney	0.009	0.991	0.000
Q63.3 Hyperplastic and giant kidney	0.009	0.991	0.000
O02 Other abnormal products of conception	0.009	0.991	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.009	0.991	0.000
Q18 Other congenital malformations of face and neck	0.009	0.991	0.000
N39.3 Stress incontinence	0.009	0.991	0.000
Q10.7 Congenital malformation of orbit	0.009	0.991	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.009	0.991	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.009	0.991	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.009	0.991	0.000
Q10.3 Other congenital malformations of eyelid	0.009	0.991	0.000
Q10.2 Congenital entropion	0.009	0.991	0.000
Q10.1 Congenital ectropion	0.009	0.991	0.000
Q10.0 Congenital ptosis	0.009	0.991	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.009	0.991	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.009	0.991	0.000
Q13.5 Blue sclera	0.009	0.991	0.000
Q13.4 Other congenital corneal malformations	0.009	0.991	0.000
Q13.3 Congenital corneal opacity	0.009	0.991	0.000
Q13.2 Other congenital malformations of iris	0.009	0.991	0.000
Q13.1 Absence of iris	0.009	0.991	0.000
Q13.0 Coloboma of iris	0.009	0.991	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.009	0.991	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.009	0.991	0.000
Q14.3 Congenital malformation of choroid	0.009	0.991	0.000
Q14.2 Congenital malformation of optic disk	0.009	0.991	0.000
Q14.1 Congenital malformation of retina	0.009	0.991	0.000
Q14.0 Congenital malformation of vitreous humour	0.009	0.991	0.000
Q15.9 Congenital malformation of eye, unspecified	0.009	0.991	0.000
Q15.8 Other specified congenital malformations of eye	0.009	0.991	0.000
Q15.0 Congenital glaucoma	0.009	0.991	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.009	0.991	0.000
Q16.5 Congenital malformation of inner ear	0.009	0.991	0.000
Q16.4 Other congenital malformations of middle ear	0.009	0.991	0.000
Q16.3 Congenital malformation of ear ossicles	0.009	0.991	0.000
Q16.2 Absence of eustachian tube	0.009	0.991	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.009	0.991	0.000
Q16.0 Congenital absence of (ear) auricle	0.009	0.991	0.000
Q17.9 Congenital malformation of ear, unspecified	0.009	0.991	0.000
Q17.8 Other specified congenital malformations of ear	0.009	0.991	0.000
Q17.4 Misplaced ear	0.009	0.991	0.000
Q17.3 Other misshapen ear	0.009	0.991	0.000
Q17.2 Microtia	0.009	0.991	0.000
Q17.1 Macrotia	0.009	0.991	0.000
Q17.0 Accessory auricle	0.009	0.991	0.000
Q25.4 Other congenital malformations of aorta	0.009	0.991	0.000
Q17.5 Prominent ear	0.009	0.991	0.000
Q54 Hypospadias	0.009	0.991	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.009	0.991	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.009	0.991	0.000
Q55 Other congenital malformations of male genital organs	0.009	0.991	0.000
I78.9 Disease of capillaries, unspecified	0.009	0.991	0.000
Q39.6 Diverticulum of oesophagus	0.009	0.991	0.000
Q66.3 Other congenital varus deformities of feet	0.009	0.991	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.008	0.991	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.008	0.991	0.000
Q68.4 Congenital bowing of tibia and fibula	0.008	0.991	0.000
Q68.3 Congenital bowing of femur	0.008	0.991	0.000
Q68.2 Congenital deformity of knee	0.008	0.991	0.000
Q68.1 Congenital deformity of hand	0.008	0.991	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.008	0.991	0.000
Q69.9 Polydactyly, unspecified	0.008	0.991	0.000
Q69.2 Accessory toe(s)	0.008	0.991	0.000
Q69.1 Accessory thumb(s)	0.008	0.991	0.000
Q69.0 Accessory finger(s)	0.008	0.991	0.000
Q70.9 Syndactyly, unspecified	0.008	0.991	0.000
Q70.4 Polysyndactyly	0.008	0.991	0.000
Q70.3 Webbed toes	0.008	0.991	0.000
Q70.2 Fused toes	0.008	0.991	0.000
Q70.1 Webbed fingers	0.008	0.991	0.000
Q70.0 Fused fingers	0.008	0.991	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.008	0.991	0.000
Q71.8 Other reduction defects of upper limb(s)	0.008	0.991	0.000
Q71.6 Lobster-claw hand	0.008	0.991	0.000
Q71.5 Longitudinal reduction defect of ulna	0.008	0.991	0.000
Q71.4 Longitudinal reduction defect of radius	0.008	0.991	0.000
Q71.3 Congenital absence of hand and finger(s)	0.008	0.991	0.000
Q71.2 Congenital absence of both forearm and hand	0.008	0.991	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.008	0.991	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.008	0.991	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.008	0.991	0.000
Q72.8 Other reduction defects of lower limb(s)	0.008	0.991	0.000
Q72.7 Split foot	0.008	0.991	0.000
Q72.6 Longitudinal reduction defect of fibula	0.008	0.991	0.000
Q72.5 Longitudinal reduction defect of tibia	0.008	0.991	0.000
Q72.4 Longitudinal reduction defect of femur	0.008	0.991	0.000
Q72.3 Congenital absence of foot and toe(s)	0.008	0.991	0.000
Q72.2 Congenital absence of both lower leg and foot	0.008	0.991	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.008	0.991	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.008	0.991	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.008	0.991	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.008	0.991	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.008	0.991	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.008	0.991	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.008	0.991	0.000
Q75.5 Oculomandibular dysostosis	0.008	0.991	0.000
Q75.4 Mandibulofacial dysostosis	0.008	0.991	0.000
Q75.3 Macrocephaly	0.008	0.991	0.000
Q75.2 Hypertelorism	0.008	0.991	0.000
Q75.1 Craniofacial dysostosis	0.008	0.991	0.000
Q75.0 Craniosynostosis	0.008	0.991	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.008	0.991	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.008	0.991	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.008	0.991	0.000
Q77.6 Chondroectodermal dysplasia	0.008	0.991	0.000
Q77.5 Diastrophic dysplasia	0.008	0.991	0.000
Q77.4 Achondroplasia	0.008	0.991	0.000
Q77.3 Chondrodysplasia punctata	0.008	0.991	0.000
Q77.2 Short rib syndrome	0.008	0.991	0.000
Q77.1 Thanatophoric short stature	0.008	0.991	0.000
Q77.0 Achondrogenesis	0.008	0.991	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.008	0.991	0.000
Q78.8 Other specified osteochondrodysplasias	0.008	0.991	0.000
Q78.6 Multiple congenital exostoses	0.008	0.991	0.000
Q78.5 Metaphyseal dysplasia	0.008	0.991	0.000
Q78.4 Enchondromatosis	0.008	0.991	0.000
Q78.3 Progressive diaphyseal dysplasia	0.008	0.991	0.000
Q78.2 Osteopetrosis	0.008	0.991	0.000
Q78.1 Polyostotic fibrous dysplasia	0.008	0.991	0.000
Q53 Undescended testicle	0.008	0.991	0.000
Q78.0 Osteogenesis imperfecta	0.008	0.991	0.000
Q66.9 Congenital deformity of feet, unspecified	0.008	0.992	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.008	0.992	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.008	0.992	0.000
Q74.3 Arthrogryposis multiplex congenita	0.008	0.992	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.008	0.992	0.000
Q74.1 Congenital malformation of knee	0.008	0.992	0.000
Q27 Other congenital malformations of peripheral vascular system	0.008	0.992	0.000
O04 Medical abortion	0.008	0.992	0.000
Q45.8 Other specified congenital malformations of digestive system	0.008	0.992	0.000
Q44.6 Cystic disease of liver	0.008	0.992	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.008	0.992	0.000
I78.8 Other diseases of capillaries	0.008	0.992	0.000
Q67.8 Other congenital deformities of chest	0.008	0.992	0.000
Q67.7 Pectus carinatum	0.008	0.992	0.000
Q67.6 Pectus excavatum	0.008	0.992	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.008	0.992	0.000
Q67.3 Plagiocephaly	0.008	0.992	0.000
Q67.2 Dolichocephaly	0.008	0.992	0.000
Q67.1 Compression facies	0.008	0.992	0.000
Q67.0 Facial asymmetry	0.008	0.992	0.000
O04.9 Complete or unspecified, without complication	0.008	0.992	0.000
Q06 Other congenital malformations of spinal cord	0.008	0.992	0.000
Q04 Other congenital malformations of brain	0.008	0.992	0.000
Q03 Congenital hydrocephalus	0.008	0.992	0.000
Q01 Encephalocele	0.008	0.992	0.000
Q00 Anencephaly and similar malformations	0.008	0.992	0.000
Q02 Microcephaly	0.008	0.992	0.000
Z83.1 Family history of other infectious and parasitic diseases	0.008	0.992	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.008	0.992	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.008	0.992	0.000
Q45.2 Congenital pancreatic cyst	0.008	0.992	0.000
Q45.1 Annular pancreas	0.008	0.992	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.008	0.992	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.008	0.992	0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.008	0.992	0.000
Q44.7 Other congenital malformations of liver	0.008	0.992	0.000
Q44.5 Other congenital malformations of bile ducts	0.008	0.992	0.000
Q44.4 Choledochal cyst	0.008	0.992	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.008	0.992	0.000
Q44.2 Atresia of bile ducts	0.008	0.992	0.000
Q44.1 Other congenital malformations of gallbladder	0.008	0.992	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.008	0.992	0.000
Q66.7 Pes cavus	0.008	0.992	0.000
Q66.6 Other congenital valgus deformities of feet	0.008	0.992	0.000
Q66.5 Congenital pes planus	0.008	0.992	0.000
Q66.4 Talipes calcaneovalgus	0.008	0.992	0.000
Q66.2 Metatarsus varus	0.008	0.992	0.000
Q66.1 Talipes calcaneovarus	0.008	0.992	0.000
Q66.0 Talipes equinovarus	0.008	0.992	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.008	0.992	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.008	0.992	0.000
Q98.7 Male with sex chromosome mosaicism	0.008	0.992	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.008	0.992	0.000
Q98.5 Karyotype 47,XYY	0.008	0.992	0.000
Q98.3 Other male with 46,XX karyotype	0.008	0.992	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.008	0.992	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.008	0.992	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.008	0.992	0.000
Q96.9 Turner's syndrome, unspecified	0.008	0.992	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.008	0.992	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.008	0.992	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.008	0.992	0.000
Q40.2 Other specified congenital malformations of stomach	0.008	0.992	0.000
Q40.1 Congenital hiatus hernia	0.008	0.992	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.008	0.992	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.008	0.992	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.008	0.992	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.008	0.992	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.008	0.992	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.008	0.992	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.008	0.992	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.008	0.992	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.008	0.992	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.008	0.992	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.008	0.992	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.008	0.992	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.008	0.992	0.000
Q25.8 Other congenital malformations of great arteries	0.008	0.992	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.008	0.992	0.000
Q25.6 Stenosis of pulmonary artery	0.008	0.992	0.000
Q25.5 Atresia of pulmonary artery	0.008	0.992	0.000
Q25.3 Stenosis of aorta	0.008	0.992	0.000
Q25.2 Atresia of aorta	0.008	0.992	0.000
Q25.0 Patent ductus arteriosus	0.008	0.992	0.000
Q25.1 Coarctation of aorta	0.008	0.992	0.000
Q05 Spina bifida	0.008	0.992	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.008	0.992	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.008	0.992	0.000
Q39.8 Other congenital malformations of oesophagus	0.008	0.992	0.000
Q39.5 Congenital dilatation of oesophagus	0.008	0.992	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.008	0.992	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.008	0.992	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.008	0.992	0.000
Q39.0 Atresia of oesophagus without fistula	0.008	0.992	0.000
Q67.5 Congenital deformity of spine	0.008	0.992	0.000
H74.4 Polyp of middle ear	0.000	0.992	0.008
O02.1 Missed abortion	0.008	0.992	0.000
Q96.8 Other variants of Turner's syndrome	0.007	0.992	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.007	0.992	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.007	0.992	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.007	0.992	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.007	0.992	0.000
Q96.0 Karyotype 45,X	0.007	0.992	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.007	0.992	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.007	0.992	0.000
Q52.7 Other congenital malformations of vulva	0.007	0.992	0.000
Q52.6 Congenital malformation of clitoris	0.007	0.992	0.000
Q52.4 Other congenital malformations of vagina	0.007	0.992	0.000
Q52.3 Imperforate hymen	0.007	0.992	0.000
Q52.2 Congenital rectovaginal fistula	0.007	0.992	0.000
Q52.1 Doubling of vagina	0.007	0.992	0.000
Q52.0 Congenital absence of vagina	0.007	0.992	0.000
Q89 Other congenital malformations, not elsewhere classified	0.008	0.992	0.000
I77.8 Other specified disorders of arteries and arterioles	0.007	0.992	0.001
Q63.0 Accessory kidney	0.007	0.992	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.008	0.992	0.000
H04.2 Epiphora	0.008	0.992	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.007	0.992	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.007	0.992	0.000
Q84 Other congenital malformations of integument	0.007	0.992	0.000
Q81 Epidermolysis bullosa	0.007	0.992	0.000
Q80 Congenital ichthyosis	0.007	0.992	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.007	0.993	0.000
Q90.9 Down's syndrome, unspecified	0.007	0.993	0.000
Q90.2 Trisomy 21, translocation	0.007	0.993	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.007	0.993	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations