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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1593
log Bayes Factor = 19.3299
Chromosome 4   position 187,195,551  (GRCh37) Explore rs1593 on Ensembl!
Variant rs1593 is listed in the   GWAS Catalog   ⇪
Variant rs1593 is part of Cluster X0136

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.000 1.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.000 1.000
Z86.7 Personal history of diseases of the circulatory system
0.000 0.002 0.998
I80 Phlebitis and thrombophlebitis
0.000 0.006 0.994
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.014 0.986
I26 Pulmonary embolism
0.000 0.043 0.957
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.068 0.932
I27 Other pulmonary heart diseases
0.000 0.104 0.896
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.165 0.835
I27.0 Primary pulmonary hypertension
0.000 0.172 0.828
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.178 0.822
Chapter IX Diseases of the circulatory system
0.000 0.190 0.810
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.214 0.786
I27.2 Other secondary pulmonary hypertension
0.000 0.217 0.783
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.295 0.705
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.323 0.677
I27.8 Other specified pulmonary heart diseases
0.000 0.330 0.670
I81 Portal vein thrombosis
0.000 0.337 0.663
I27.9 Pulmonary heart disease, unspecified
0.000 0.349 0.651
I30-I52 Other forms of heart disease
0.000 0.351 0.649
I28 Other diseases of pulmonary vessels
0.000 0.356 0.644
I27.1 Kyphoscoliotic heart disease
0.000 0.358 0.642
I85 Oesophageal varices
0.000 0.361 0.639
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.365 0.635
I89.0 Lymphoedema, not elsewhere classified
0.000 0.392 0.608
I49 Other cardiac arrhythmias
0.000 0.395 0.605
I88 Nonspecific lymphadenitis
0.000 0.412 0.588
I00-I02 Acute rheumatic fever
0.000 0.419 0.581
I05-I09 Chronic rheumatic heart diseases
0.000 0.420 0.580
I38 Endocarditis, valve unspecified
0.000 0.421 0.579
I30 Acute pericarditis
0.000 0.423 0.577
I86 Varicose veins of other sites
0.000 0.427 0.573
I49.5 Sick sinus syndrome
0.000 0.430 0.570
I51 Complications and ill-defined descriptions of heart disease
0.000 0.431 0.569
I82 Other venous embolism and thrombosis
0.000 0.440 0.560
I85.0 Oesophageal varices with bleeding
0.000 0.448 0.552
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.451 0.549
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.467 0.532
I89.1 Lymphangitis
0.000 0.471 0.529
I07 Rheumatic tricuspid valve diseases
0.000 0.477 0.523
I87 Other disorders of veins
0.000 0.479 0.521
I30.9 Acute pericarditis, unspecified
0.000 0.485 0.515
I37 Pulmonary valve disorders
0.000 0.489 0.511
I49.0 Ventricular fibrillation and flutter
0.000 0.494 0.506
I51.7 Cardiomegaly
0.000 0.500 0.500
I34 Nonrheumatic mitral valve disorders
0.000 0.501 0.499
I44 Atrioventricular and left bundle-branch block
0.000 0.503 0.497
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.515 0.485
I07.1 Tricuspid insufficiency
0.000 0.518 0.482
I51.0 Cardiac septal defect, acquired
0.000 0.521 0.479
I33 Acute and subacute endocarditis
0.000 0.524 0.476
I49.3 Ventricular premature depolarisation
0.000 0.529 0.471
I51.4 Myocarditis, unspecified
0.000 0.534 0.466
I52 Other heart disorders in diseases classified elsewhere
0.000 0.534 0.465
I48 Atrial fibrillation and flutter
0.000 0.534 0.465
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.534 0.465
I41 Myocarditis in diseases classified elsewhere
0.000 0.534 0.465
I40 Acute myocarditis
0.000 0.534 0.465
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.534 0.465
I32 Pericarditis in diseases classified elsewhere
0.000 0.534 0.465
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.538 0.461
I28.1 Aneurysm of pulmonary artery
0.000 0.538 0.461
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.538 0.461
I49.1 Atrial premature depolarisation
0.000 0.540 0.460
I82.8 Embolism and thrombosis of other specified veins
0.000 0.544 0.456
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.544 0.456
I44.0 Atrioventricular block, first degree
0.000 0.548 0.452
I36 Nonrheumatic tricuspid valve disorders
0.000 0.550 0.450
I37.1 Pulmonary valve insufficiency
0.000 0.553 0.447
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.556 0.444
I30.1 Infective pericarditis
0.000 0.558 0.442
I86.4 Gastric varices
0.000 0.558 0.442
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.561 0.439
I95 Hypotension
0.000 0.561 0.439
I46 Cardiac arrest
0.000 0.563 0.437
I28.8 Other specified diseases of pulmonary vessels
0.000 0.563 0.437
I44.2 Atrioventricular block, complete
0.000 0.563 0.437
I49.2 Junctional premature depolarisation
0.000 0.566 0.433
I35 Nonrheumatic aortic valve disorders
0.000 0.572 0.428
I88.8 Other nonspecific lymphadenitis
0.000 0.578 0.422
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.578 0.422
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.578 0.422
I49.8 Other specified cardiac arrhythmias
0.000 0.582 0.418
I02 Rheumatic chorea
0.000 0.583 0.417
I01 Rheumatic fever with heart involvement
0.000 0.583 0.417
I00 Rheumatic fever without mention of heart involvement
0.000 0.583 0.417
I49.9 Cardiac arrhythmia, unspecified
0.000 0.584 0.416
I06 Rheumatic aortic valve diseases
0.000 0.584 0.416
I30.8 Other forms of acute pericarditis
0.000 0.586 0.414
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.586 0.414
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.588 0.412
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.589 0.411
I86.3 Vulval varices
0.000 0.589 0.411
I86.2 Pelvic varices
0.000 0.589 0.411
I86.0 Sublingual varices
0.000 0.589 0.411
I51.5 Myocardial degeneration
0.000 0.592 0.408
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.592 0.408
I82.1 Thrombophlebitis migrans
0.000 0.599 0.401
I82.0 Budd-Chiari syndrome
0.000 0.599 0.401
I35.1 Aortic (valve) insufficiency
0.000 0.599 0.401
I09 Other rheumatic heart diseases
0.000 0.599 0.400
I34.1 Mitral (valve) prolapse
0.000 0.601 0.399
I34.0 Mitral (valve) insufficiency
0.000 0.609 0.391
I86.8 Varicose veins of other specified sites
0.000 0.615 0.385
I95.1 Orthostatic hypotension
0.000 0.616 0.384
I95.2 Hypotension due to drugs
0.000 0.619 0.381
I44.3 Other and unspecified atrioventricular block
0.000 0.621 0.379
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.624 0.376
I51.6 Cardiovascular disease, unspecified
0.000 0.624 0.376
I07.9 Tricuspid valve disease, unspecified
0.000 0.625 0.375
I07.8 Other tricuspid valve diseases
0.000 0.625 0.375
I07.2 Tricuspid stenosis with insufficiency
0.000 0.625 0.375
I07.0 Tricuspid stenosis
0.000 0.625 0.375
I87.9 Disorder of vein, unspecified
0.000 0.626 0.374
I87.0 Postphlebitic syndrome
0.000 0.626 0.374
I86.1 Scrotal varices
0.000 0.628 0.372
I82.2 Embolism and thrombosis of vena cava
0.000 0.628 0.372
I37.9 Pulmonary valve disorder, unspecified
0.000 0.634 0.366
I37.8 Other pulmonary valve disorders
0.000 0.634 0.366
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.634 0.366
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.636 0.363
I87.8 Other specified disorders of veins
0.000 0.637 0.363
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.638 0.362
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.642 0.358
I99 Other and unspecified disorders of circulatory system
0.000 0.643 0.357
I44.5 Left posterior fascicular block
0.000 0.644 0.356
I44.4 Left anterior fascicular block
0.000 0.644 0.356
I82.3 Embolism and thrombosis of renal vein
0.000 0.645 0.355
I33.0 Acute and subacute infective endocarditis
0.000 0.648 0.351
I85.9 Oesophageal varices without bleeding
0.000 0.655 0.345
I97.1 Other functional disturbances following cardiac surgery
0.000 0.655 0.345
I33.9 Acute endocarditis, unspecified
0.000 0.659 0.341
I05 Rheumatic mitral valve diseases
0.000 0.659 0.341
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.666 0.334
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.666 0.334
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.666 0.334
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.666 0.334
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.666 0.334
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.666 0.334
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.666 0.334
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.666 0.334
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.666 0.334
I40.9 Acute myocarditis, unspecified
0.000 0.666 0.334
I40.8 Other acute myocarditis
0.000 0.666 0.334
I40.1 Isolated myocarditis
0.000 0.666 0.334
I40.0 Infective myocarditis
0.000 0.666 0.334
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.666 0.334
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.666 0.334
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.666 0.334
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.666 0.334
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.666 0.334
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.666 0.334
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.666 0.334
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.666 0.334
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.666 0.334
I48.4 Atypical atrial flutter
0.000 0.666 0.334
I48.3 Typical atrial flutter
0.000 0.666 0.334
I48.2 Chronic atrial fibrillation
0.000 0.666 0.334
I48.1 Persistent atrial fibrillation
0.000 0.666 0.334
I48.0 Paroxysmal atrial fibrillation
0.000 0.666 0.334
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.666 0.334
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.666 0.334
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.666 0.334
I51.9 Heart disease, unspecified
0.000 0.666 0.334
I35.8 Other aortic valve disorders
0.000 0.669 0.331
I46.0 Cardiac arrest with successful resuscitation
0.000 0.672 0.328
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.677 0.323
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.677 0.323
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.677 0.323
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.677 0.323
I95.0 Idiopathic hypotension
0.000 0.685 0.315
I46.1 Sudden cardiac death, so described
0.000 0.686 0.314
I87.1 Compression of vein
0.000 0.691 0.309
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.691 0.309
I83 Varicose veins of lower extremities
0.000 0.691 0.309
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.693 0.307
I45 Other conduction disorders
0.000 0.694 0.306
I42 Cardiomyopathy
0.000 0.697 0.303
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.701 0.299
I01.8 Other acute rheumatic heart disease
0.000 0.701 0.299
I01.2 Acute rheumatic myocarditis
0.000 0.701 0.299
I01.1 Acute rheumatic endocarditis
0.000 0.701 0.299
I01.0 Acute rheumatic pericarditis
0.000 0.701 0.299
I02.9 Rheumatic chorea without heart involvement
0.000 0.701 0.299
I02.0 Rheumatic chorea with heart involvement
0.000 0.701 0.299
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.702 0.298
I06.8 Other rheumatic aortic valve diseases
0.000 0.702 0.298
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.702 0.298
I06.1 Rheumatic aortic insufficiency
0.000 0.702 0.298
I06.0 Rheumatic aortic stenosis
0.000 0.702 0.298
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.704 0.295
I97.0 Postcardiotomy syndrome
0.000 0.704 0.295
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.705 0.295
I09.8 Other specified rheumatic heart diseases
0.000 0.713 0.287
I09.2 Chronic rheumatic pericarditis
0.000 0.713 0.287
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.713 0.287
I09.0 Rheumatic myocarditis
0.000 0.713 0.287
I37.0 Pulmonary valve stenosis
0.000 0.714 0.286
I08 Multiple valve diseases
0.000 0.715 0.285
I35.9 Aortic valve disorder, unspecified
0.000 0.721 0.279
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.722 0.278
I95.8 Other hypotension
0.000 0.724 0.276
I09.9 Rheumatic heart disease, unspecified
0.000 0.728 0.272
Z92.1 Personal history of long-term (current) use of anticoagulants
0.000 0.729 0.271
I46.9 Cardiac arrest, unspecified
0.000 0.735 0.265
I44.7 Left bundle-branch block, unspecified
0.000 0.736 0.264
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.737 0.263
I44.6 Other and unspecified fascicular block
0.000 0.740 0.260
I49.4 Other and unspecified premature depolarisation
0.000 0.744 0.255
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.746 0.254
I45.8 Other specified conduction disorders
0.000 0.750 0.250
I05.8 Other mitral valve diseases
0.000 0.755 0.244
I05.2 Mitral stenosis with insufficiency
0.000 0.756 0.244
I45.5 Other specified heart block
0.000 0.757 0.243
I05.1 Rheumatic mitral insufficiency
0.000 0.762 0.238
I05.9 Mitral valve disease, unspecified
0.000 0.764 0.236
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.767 0.233
I50 Heart failure
0.000 0.768 0.232
I45.9 Conduction disorder, unspecified
0.000 0.770 0.230
I51.8 Other ill-defined heart diseases
0.000 0.771 0.229
I42.2 Other hypertrophic cardiomyopathy
0.000 0.773 0.227
I08.0 Disorders of both mitral and aortic valves
0.000 0.774 0.226
I42.8 Other cardiomyopathies
0.000 0.778 0.222
I45.4 Nonspecific intraventricular block
0.000 0.778 0.222
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.778 0.221
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.778 0.221
I98.0 Cardiovascular syphilis
0.000 0.778 0.221
I42.6 Alcoholic cardiomyopathy
0.000 0.780 0.220
I45.0 Right fascicular block
0.000 0.780 0.220
I60-I69 Cerebrovascular diseases
0.000 0.780 0.220
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.783 0.217
I42.5 Other restrictive cardiomyopathy
0.000 0.783 0.217
I42.4 Endocardial fibroelastosis
0.000 0.783 0.217
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.783 0.217
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.785 0.215
I45.6 Preexcitation syndrome
0.000 0.790 0.210
I08.9 Multiple valve disease, unspecified
0.000 0.796 0.204
I45.3 Trifascicular block
0.000 0.796 0.203
I50.9 Heart failure, unspecified
0.000 0.800 0.200
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.800 0.199
I42.9 Cardiomyopathy, unspecified
0.000 0.801 0.199
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.802 0.198
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.806 0.194
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.806 0.194
I05.0 Mitral stenosis
0.000 0.806 0.193
I31 Other diseases of pericardium
0.000 0.810 0.190
I60 Subarachnoid haemorrhage
0.000 0.811 0.189
I63 Cerebral infarction
0.000 0.815 0.185
I63.8 Other cerebral infarction
0.000 0.823 0.177
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.830 0.170
I45.2 Bifascicular block
0.000 0.835 0.165
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.837 0.163
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.838 0.162
I47 Paroxysmal tachycardia
0.000 0.842 0.158
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.842 0.158
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.848 0.152
I44.1 Atrioventricular block, second degree
0.000 0.849 0.151
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.849 0.151
I60.8 Other subarachnoid haemorrhage
0.000 0.851 0.149
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.851 0.149
I08.8 Other multiple valve diseases
0.000 0.854 0.146
I95.9 Hypotension, unspecified
0.000 0.854 0.146
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.856 0.144
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.860 0.140
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.863 0.137
I31.8 Other specified diseases of pericardium
0.000 0.864 0.136
I31.2 Haemopericardium, not elsewhere classified
0.000 0.864 0.136
I31.0 Chronic adhesive pericarditis
0.000 0.864 0.136
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.864 0.136
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.864 0.135
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.867 0.133
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.867 0.133
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.867 0.133
I10-I15 Hypertensive diseases
0.000 0.867 0.132
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.872 0.128
I31.1 Chronic constrictive pericarditis
0.000 0.876 0.124
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.876 0.124
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.877 0.123
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.879 0.121
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.885 0.115
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.887 0.113
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.887 0.113
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.887 0.113
I68.0 Cerebral amyloid angiopathy
0.000 0.887 0.113
I98.2 Oesophageal varices in diseases classified elsewhere
0.001 0.890 0.109
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.893 0.107
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.893 0.107
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.893 0.107
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.893 0.107
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.893 0.107
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.893 0.107
I47.0 Reentry ventricular arrhythmia
0.000 0.894 0.106
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.896 0.104
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.897 0.103
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.897 0.103
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.902 0.098
I42.0 Dilated cardiomyopathy
0.000 0.902 0.097
I13 Hypertensive heart and renal disease
0.000 0.905 0.095
I35.0 Aortic (valve) stenosis
0.000 0.906 0.094
I62 Other nontraumatic intracranial haemorrhage
0.000 0.908 0.092
I69 Sequelae of cerebrovascular disease
0.000 0.909 0.091
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.911 0.089
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.913 0.087
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.913 0.087
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.913 0.087
I65.1 Occlusion and stenosis of basilar artery
0.000 0.913 0.087
I11 Hypertensive heart disease
0.000 0.918 0.082
I15 Secondary hypertension
0.000 0.919 0.081
I47.2 Ventricular tachycardia
0.000 0.928 0.071
I31.3 Pericardial effusion (noninflammatory)
0.000 0.929 0.071
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.930 0.070
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.931 0.068
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.931 0.068
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.931 0.068
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.931 0.068
I31.9 Disease of pericardium, unspecified
0.000 0.932 0.068
I69.3 Sequelae of cerebral infarction
0.000 0.932 0.068
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.932 0.068
I62.1 Nontraumatic extradural haemorrhage
0.000 0.933 0.066
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.938 0.061
I15.9 Seconday hypertension, unspecified
0.000 0.941 0.059
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.941 0.059
I15.8 Other secondary hypertension
0.000 0.941 0.058
I15.2 Hypertension secondary to endocrine disorders
0.000 0.941 0.058
I15.0 Renovascular hypertension
0.000 0.941 0.058
I12 Hypertensive renal disease
0.000 0.942 0.058
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.943 0.056
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.945 0.054
I50.0 Congestive heart failure
0.000 0.950 0.050
I61 Intracerebral haemorrhage
0.000 0.953 0.047
I65.2 Occlusion and stenosis of carotid artery
0.000 0.954 0.046
I67 Other cerebrovascular diseases
0.000 0.954 0.046
I15.1 Hypertension secondary to other renal disorders
0.000 0.956 0.043
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.958 0.042
I63.9 Cerebral infarction, unspecified
0.000 0.959 0.041
I12.0 Hypertensive renal disease with renal failure
0.000 0.963 0.037
I61.8 Other intracerebral haemorrhage
0.000 0.964 0.035
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.965 0.035
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.966 0.034
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.966 0.034
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.967 0.033
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.967 0.033
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.967 0.033
I67.5 Moyamoya disease
0.000 0.967 0.033
I67.4 Hypertensive encephalopathy
0.000 0.967 0.033
I67.3 Progressive vascular leukoencephalopathy
0.000 0.967 0.033
I20-I25 Ischaemic heart diseases
0.000 0.967 0.033
I47.1 Supraventricular tachycardia
0.000 0.968 0.032
I67.2 Cerebral atherosclerosis
0.000 0.968 0.032
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.968 0.031
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.968 0.031
I45.1 Other and unspecified right bundle-branch block
0.000 0.970 0.030
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.001 0.970 0.029
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.971 0.029
I67.1 Cerebral aneurysm, nonruptured
0.000 0.972 0.028
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.001 0.973 0.026
I61.4 Intracerebral haemorrhage in cerebellum
0.001 0.975 0.025
I74 Arterial embolism and thrombosis
0.000 0.975 0.025
I24 Other acute ischaemic heart diseases
0.000 0.975 0.025
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.977 0.023
I61.5 Intracerebral haemorrhage, intraventricular
0.001 0.977 0.022
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.977 0.022
I23 Certain current complications following acute myocardial infarction
0.000 0.978 0.022
I67.8 Other specified cerebrovascular diseases
0.000 0.979 0.021
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.980 0.020
I22 Subsequent myocardial infarction
0.000 0.980 0.020
I74.5 Embolism and thrombosis of iliac artery
0.000 0.981 0.019
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.981 0.019
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.981 0.019
I70 Atherosclerosis
0.000 0.982 0.018
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.982 0.018
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.982 0.018
I24.1 Dressler's syndrome
0.000 0.982 0.018
I74.8 Embolism and thrombosis of other arteries
0.000 0.982 0.018
I12.9 Hypertensive renal disease without renal failure
0.001 0.982 0.017
I50.1 Left ventricular failure
0.000 0.983 0.017
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.983 0.017
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.983 0.017
I78 Diseases of capillaries
0.000 0.984 0.016
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.984 0.016
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.984 0.016
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.984 0.016
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.984 0.016
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.984 0.016
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.984 0.016
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.984 0.016
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.984 0.016
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.984 0.016
C18.9 Colon, unspecified
0.000 0.984 0.016
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.985 0.015
J43.9 Emphysema, unspecified
0.015 0.985 0.000
I23.8 Other current complications following acute myocardial infarction
0.000 0.986 0.014
I70.0 Atherosclerosis of aorta
0.000 0.987 0.013
I70.9 Generalised and unspecified atherosclerosis
0.000 0.987 0.013
I70.8 Atherosclerosis of other arteries
0.000 0.987 0.013
I22.8 Subsequent myocardial infarction of other sites
0.000 0.987 0.013
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.987 0.013
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.987 0.012
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.987 0.012
C18 Malignant neoplasm of colon
0.000 0.988 0.012
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.988 0.012
I79.1 Aortitis in diseases classified elsewhere
0.000 0.988 0.012
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.988 0.012
C18.2 Ascending colon
0.000 0.988 0.012
I78.9 Disease of capillaries, unspecified
0.000 0.988 0.012
I72 Other aneurysm
0.000 0.988 0.011
I73 Other peripheral vascular diseases
0.000 0.989 0.011
C18.6 Descending colon
0.000 0.989 0.011
C18.7 Sigmoid colon
0.000 0.989 0.011
I78.8 Other diseases of capillaries
0.000 0.989 0.011
I70.1 Atherosclerosis of renal artery
0.000 0.989 0.010
N18.4 Chronic kidney disease, stage 4
0.000 0.989 0.011
C18.1 Appendix
0.000 0.989 0.011
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.990 0.010
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.990 0.010
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.990 0.009
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.990 0.009
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.990 0.009
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.990 0.009
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.991 0.009
I72.9 Aneurysm of unspecified site
0.000 0.991 0.009
R79.8 Other specified abnormal findings of blood chemistry
0.000 0.991 0.009
I72.2 Aneurysm of renal artery
0.000 0.991 0.008
C18.8 Overlapping lesion of colon
0.000 0.991 0.008
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.991 0.008
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.991 0.008
I72.1 Aneurysm of artery of upper extremity
0.000 0.991 0.008
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.991 0.008
I73.8 Other specified peripheral vascular diseases
0.000 0.992 0.008
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.992 0.008
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.001 0.992 0.008
C18.5 Splenic flexure
0.000 0.992 0.008
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.992 0.008
I24.8 Other forms of acute ischaemic heart disease
0.000 0.992 0.008
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.992 0.008
I72.3 Aneurysm of iliac artery
0.000 0.992 0.008
I67.9 Cerebrovascular disease, unspecified
0.000 0.992 0.008
Q21.1 Atrial septal defect
0.000 0.992 0.008
I78.1 Naevus, nonneoplastic
0.000 0.992 0.008
C18.0 Caecum
0.000 0.992 0.008
I72.0 Aneurysm of carotid artery
0.000 0.992 0.007
J43 Emphysema
0.008 0.992 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.000 0.993 0.007
H73.8 Other specified disorders of tympanic membrane
0.007 0.993 0.000
I72.8 Aneurysm of other specified arteries
0.000 0.993 0.007
C18.3 Hepatic flexure
0.000 0.993 0.006
C18.4 Transverse colon
0.000 0.994 0.006
M79.62 Pain in limb (Upper arm)
0.000 0.994 0.006
M54.99 Dorsalgia, unspecified (Site unspecified)
0.000 0.994 0.006
M54.96 Dorsalgia, unspecified (Lumbar region)
0.000 0.994 0.006
J43.2 Centrilobular emphysema
0.006 0.994 0.000
M79.8 Other specified soft tissue disorders
0.000 0.994 0.006
M79.6 Pain in limb
0.000 0.994 0.006
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.000 0.994 0.006
M54.9 Dorsalgia, unspecified
0.000 0.994 0.006
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.000 0.994 0.006
M79.69 Pain in limb (Site unspecified)
0.000 0.994 0.006
I71 Aortic aneurysm and dissection
0.000 0.994 0.006
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.994 0.005
M79.80 Other specified soft tissue disorders (Multiple sites)
0.000 0.994 0.006
J43.8 Other emphysema
0.006 0.994 0.000
J43.1 Panlobular emphysema
0.006 0.994 0.000
J43.0 MacLeod's syndrome
0.006 0.994 0.000
I73.0 Raynaud's syndrome
0.000 0.994 0.006
E89.0 Postprocedural hypothyroidism
0.000 0.994 0.006
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.000 0.995 0.005
M79.63 Pain in limb (Forearm)
0.000 0.995 0.005
M79.82 Other specified soft tissue disorders (Upper arm)
0.000 0.995 0.005
R22.2 Localised swelling, mass and lump, trunk
0.000 0.995 0.005
I72.4 Aneurysm of artery of lower extremity
0.000 0.995 0.005
M54.94 Dorsalgia, unspecified (Thoracic region)
0.000 0.995 0.005
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.005 0.995 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.000 0.995 0.005
M79.66 Pain in limb (Lower leg)
0.000 0.995 0.005
M79.83 Other specified soft tissue disorders (Forearm)
0.000 0.995 0.005
H60.9 Otitis externa, unspecified
0.005 0.995 0.000
M79.61 Pain in limb (Shoulder region)
0.000 0.995 0.005
H60 Otitis externa
0.005 0.995 0.000
Q21 Congenital malformations of cardiac septa
0.000 0.995 0.005
M79.89 Other specified soft tissue disorders (Site unspecified)
0.000 0.995 0.005
R22.9 Localised swelling, mass and lump, unspecified
0.000 0.995 0.005
M79.64 Pain in limb (Hand)
0.000 0.995 0.005
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.995 0.005
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.000 0.995 0.005
M79.88 Other specified soft tissue disorders (Other)
0.000 0.995 0.005
M79.81 Other specified soft tissue disorders (Shoulder region)
0.000 0.995 0.005
M79.67 Pain in limb (Ankle and foot)
0.000 0.995 0.005
K85.1 Biliary acute pancreatitis
0.005 0.995 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.000 0.995 0.004
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.000 0.995 0.004
M54.92 Dorsalgia, unspecified (Cervical region)
0.000 0.995 0.004
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.000 0.995 0.004
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.995 0.004
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.995 0.004
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.995 0.004
S09.9 Unspecified injury of head
0.000 0.995 0.005
M79.68 Pain in limb (Other)
0.000 0.995 0.004
I71.0 Dissection of aorta [any part]
0.000 0.995 0.004
N18 Chronic renal failure
0.000 0.995 0.005
M79.60 Pain in limb (Multiple sites)
0.000 0.995 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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