TreeWAS – Variant ID: rs160441

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.173	0.827	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.165	0.835	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.163	0.836	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.163	0.837	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.160	0.840	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.160	0.840	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.158	0.842	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.155	0.845	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.152	0.848	0.000
T36 Poisoning by systemic antibiotics	0.143	0.857	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.142	0.858	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.141	0.859	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.140	0.860	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.139	0.861	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.137	0.863	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.136	0.864	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.136	0.864	0.000
T45.0 Antiallergic and antiemetic drugs	0.133	0.867	0.000
T47.0 Histamine H(2)-receptor antagonists	0.132	0.868	0.000
T45.4 Iron and its compounds	0.130	0.870	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.130	0.870	0.000
T47.6 Antidiarrhoeal drugs	0.130	0.870	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.129	0.870	0.000
T47.4 Other laxatives	0.128	0.872	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.127	0.873	0.000
T45.5 Anticoagulants	0.125	0.874	0.000
T36.0 Penicillins	0.125	0.875	0.000
T47.2 Stimulant laxatives	0.124	0.876	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.121	0.879	0.000
T42.3 Barbiturates	0.120	0.880	0.000
T45.2 Vitamins, not elsewhere classified	0.120	0.880	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.119	0.881	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.119	0.881	0.000
T43.9 Psychotropic drug, unspecified	0.118	0.882	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.118	0.882	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.117	0.883	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.117	0.883	0.000
T47.7 Emetics	0.117	0.883	0.000
T47.5 Digestants	0.117	0.883	0.000
T47.3 Saline and osmotic laxatives	0.117	0.883	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.117	0.883	0.000
T45.8 Other primarily systemic and haematological agents	0.117	0.883	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.117	0.883	0.000
T45.6 Fibrinolysis-affecting drugs	0.117	0.883	0.000
T45.3 Enzymes, not elsewhere classified	0.117	0.883	0.000
T38.1 Thyroid hormones and substitutes	0.116	0.884	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.115	0.885	0.000
T46.7 Peripheral vasodilators	0.115	0.885	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.115	0.885	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.115	0.885	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.113	0.887	0.000
T42.2 Succinimides and oxazolidinediones	0.113	0.887	0.000
T43.6 Psychostimulants with abuse potential	0.113	0.887	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.112	0.888	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.110	0.889	0.000
T42.1 Iminostilbenes	0.109	0.890	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.109	0.891	0.000
T38.9 Other and unspecified hormone antagonists	0.109	0.891	0.000
T38.7 Androgens and anabolic congeners	0.109	0.891	0.000
T38.5 Other oestrogens and progestogens	0.109	0.891	0.000
T38.4 Oral contraceptives	0.109	0.891	0.000
T38.2 Antithyroid drugs	0.109	0.891	0.000
T38.0 Glucocorticoids and synthetic analogues	0.109	0.891	0.000
T48.5 Anti-common-cold drugs	0.108	0.892	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.107	0.893	0.000
T46.1 Calcium-channel blockers	0.106	0.894	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.106	0.894	0.000
T36.4 Tetracyclines	0.105	0.895	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.103	0.896	0.000
T40.6 Other and unspecified narcotics	0.103	0.897	0.000
T36.9 Systemic antibiotic, unspecified	0.102	0.897	0.000
T36.7 Antifungal antibiotics, systemically used	0.102	0.897	0.000
T36.6 Rifamycins	0.102	0.897	0.000
T36.5 Aminoglycosides	0.102	0.897	0.000
T36.2 Chloramphenicol group	0.102	0.897	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.102	0.897	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.102	0.898	0.000
T36.8 Other systemic antibiotics	0.102	0.898	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.101	0.899	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.101	0.899	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.101	0.899	0.000
T42.0 Hydantoin derivatives	0.098	0.901	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.098	0.902	0.000
T48.4 Expectorants	0.098	0.902	0.000
T48.3 Antitussives	0.098	0.902	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.098	0.902	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.098	0.902	0.000
T48.0 Oxytocic drugs	0.098	0.902	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.097	0.902	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.097	0.902	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.097	0.902	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.097	0.902	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.097	0.902	0.000
T44.0 Anticholinesterase agents	0.097	0.902	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.097	0.903	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.094	0.906	0.000
T42.4 Benzodiazepines	0.093	0.907	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.093	0.907	0.000
T37.5 Antiviral drugs	0.093	0.907	0.000
T37.4 Anthelminthics	0.093	0.907	0.000
T37.3 Other antiprotozoal drugs	0.093	0.907	0.000
T37.1 Antimycobacterial drugs	0.093	0.907	0.000
T37.0 Sulphonamides	0.093	0.907	0.000
T36.3 Macrolides	0.092	0.908	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.088	0.912	0.000
T41.5 Therapeutic gases	0.087	0.913	0.000
T41.4 Anaesthetic, unspecified	0.087	0.913	0.000
T41.3 Local anaesthetics	0.087	0.913	0.000
T41.1 Intravenous anaesthetics	0.087	0.913	0.000
T41.0 Inhaled anaesthetics	0.087	0.913	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.087	0.913	0.000
T40.5 Cocaine	0.086	0.914	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.086	0.914	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.086	0.914	0.000
T40.8 Lysergide [LSD]	0.086	0.914	0.000
T40.7 Cannabis (derivatives)	0.086	0.914	0.000
T40.0 Opium	0.086	0.914	0.000
T40.3 Methadone	0.085	0.914	0.000
T41.2 Other and unspecified general anaesthetics	0.083	0.917	0.000
T40.1 Heroin	0.081	0.919	0.000
T49.9 Topical agent, unspecified	0.081	0.919	0.000
T49.8 Other topical agents	0.081	0.919	0.000
T49.7 Dental drugs, topically applied	0.081	0.919	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.081	0.919	0.000
T49.5 Ophthalmological drugs and preparations	0.081	0.919	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.081	0.919	0.000
T49.3 Emollients, demulcents and protectants	0.081	0.919	0.000
T49.2 Local astringents and local detergents	0.081	0.919	0.000
T49.1 Antipruritics	0.081	0.919	0.000
T50.1 Loop [high-ceiling] diuretics	0.075	0.924	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.073	0.927	0.000
T50.7 Analeptics and opioid receptor antagonists	0.073	0.927	0.000
T50.5 Appetite depressants	0.073	0.927	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.073	0.927	0.000
T50.0 Mineralocorticoids and their antagonists	0.073	0.927	0.000
T40.2 Other opioids	0.072	0.928	0.000
T43.2 Other and unspecified antidepressants	0.071	0.929	0.000
T40.4 Other synthetic narcotics	0.070	0.929	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.070	0.930	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.069	0.931	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.069	0.931	0.000
T50.8 Diagnostic agents	0.068	0.932	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.066	0.934	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.066	0.934	0.000
T50.4 Drugs affecting uric acid metabolism	0.065	0.934	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.058	0.941	0.001
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.056	0.944	0.000
T39.4 Antirheumatics, not elsewhere classified	0.047	0.953	0.000
T39.2 Pyrazolone derivatives	0.047	0.953	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.040	0.960	0.000
T39.1 4-Aminophenol derivatives	0.037	0.963	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.037	0.963	0.000
M25.50 Pain in joint (Multiple sites)	0.000	0.977	0.023
T39.0 Salicylates	0.022	0.978	0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.019	0.981	0.000
D03 Melanoma in situ	0.019	0.981	0.000
D03.5 Melanoma in situ of trunk	0.018	0.982	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.018	0.982	0.000
K22.4 Dyskinesia of oesophagus	0.000	0.982	0.018
S83.2 Tear of meniscus, current	0.000	0.983	0.017
D03.3 Melanoma in situ of other and unspecified parts of face	0.017	0.983	0.000
D03.4 Melanoma in situ of scalp and neck	0.016	0.984	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.016	0.984	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.015	0.985	0.000
H18.8 Other specified disorders of cornea	0.000	0.986	0.014
D03.9 Melanoma in situ, unspecified	0.013	0.986	0.000
D03.0 Melanoma in situ of lip	0.013	0.986	0.000
D03.8 Melanoma in situ of other sites	0.013	0.987	0.000
H18 Other disorders of cornea	0.000	0.988	0.012
H18.5 Hereditary corneal dystrophies	0.000	0.988	0.012
D03.1 Melanoma in situ of eyelid, including canthus	0.011	0.988	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.011	0.989	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.010	0.990	0.000
H18.0 Corneal pigmentations and deposits	0.000	0.990	0.010
H18.4 Corneal degeneration	0.000	0.990	0.010
H18.1 Bullous keratopathy	0.000	0.991	0.009
H18.3 Changes in corneal membranes	0.000	0.991	0.009
H18.7 Other corneal deformities	0.000	0.991	0.009
Y40.0 Penicillins	0.000	0.991	0.009
H18.9 Disorder of cornea, unspecified	0.000	0.992	0.008
H34.2 Other retinal artery occlusions	0.008	0.992	0.000
Z89.5 Acquired absence of leg at or below knee	0.008	0.992	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.008	0.992	0.000
H18.6 Keratoconus	0.000	0.993	0.007
Z89.6 Acquired absence of leg above knee	0.007	0.993	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.993	0.007
H34.8 Other retinal vascular occlusions	0.007	0.993	0.000
Z89 Acquired absence of limb	0.007	0.993	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.994	0.006
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.994	0.006
C43 Malignant melanoma of skin	0.006	0.994	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.006	0.994	0.000
H34 Retinal vascular occlusions	0.006	0.994	0.000
H18.2 Other corneal oedema	0.000	0.994	0.006
C43.9 Malignant melanoma of skin, unspecified	0.006	0.994	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.006	0.994	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.994	0.006
S83.0 Dislocation of patella	0.000	0.994	0.006
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.006	0.994	0.000
S83.7 Injury to multiple structures of knee	0.000	0.995	0.005
S83.3 Tear of articular cartilage of knee, current	0.000	0.995	0.005
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.995	0.005
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.995	0.005
C43.3 Malignant melanoma of other and unspecified parts of face	0.005	0.995	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.005	0.995	0.000
Z04.3 Examination and observation following other accident	0.000	0.995	0.005
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.995	0.005
Z89.3 Acquired absence of both upper limbs [any level]	0.005	0.995	0.000
Z89.1 Acquired absence of hand and wrist	0.005	0.995	0.000
S83.1 Dislocation of knee	0.000	0.995	0.005
C43.8 Overlapping malignant melanoma of skin	0.005	0.995	0.000
C43.0 Malignant melanoma of lip	0.005	0.995	0.000
H34.0 Transient retinal artery occlusion	0.005	0.995	0.000
Z89.2 Acquired absence of upper limb above wrist	0.005	0.995	0.000
C43.4 Malignant melanoma of scalp and neck	0.005	0.995	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.004	0.995	0.000
H34.1 Central retinal artery occlusion	0.004	0.996	0.000
M22.8 Other disorders of patella	0.004	0.996	0.000
Z89.9 Acquired absence of limb, unspecified	0.004	0.996	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.004	0.996	0.000
H34.9 Retinal vascular occlusion, unspecified	0.004	0.996	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
C43.5 Malignant melanoma of trunk	0.004	0.996	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
Q39 Congenital malformations of oesophagus	0.004	0.996	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
Y51.0 Anticholinesterase agents	0.004	0.996	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.004	0.996	0.000
Q44.6 Cystic disease of liver	0.004	0.996	0.000
Q39.6 Diverticulum of oesophagus	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
Q43.0 Meckel's diverticulum	0.004	0.996	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.004	0.996	0.000
M24.54 Contracture of joint (Hand)	0.004	0.996	0.000
Q39.4 Oesophageal web	0.004	0.996	0.000
H90.5 Sensorineural hearing loss, unspecified	0.004	0.996	0.000
Q43.8 Other specified congenital malformations of intestine	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q39.8 Other congenital malformations of oesophagus	0.003	0.997	0.000
Q39.5 Congenital dilatation of oesophagus	0.003	0.997	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.003	0.997	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.003	0.997	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.003	0.997	0.000
Q39.0 Atresia of oesophagus without fistula	0.003	0.997	0.000
M24.5 Contracture of joint	0.003	0.997	0.000
R50.8 Other specified fever	0.000	0.997	0.003
Q44.5 Other congenital malformations of bile ducts	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q44.4 Choledochal cyst	0.003	0.997	0.000
Z89.4 Acquired absence of foot and ankle	0.003	0.997	0.000
H70.9 Mastoiditis, unspecified	0.000	0.997	0.003
Q43.3 Congenital malformations of intestinal fixation	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.003	0.997	0.000
Q44.7 Other congenital malformations of liver	0.003	0.997	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.003	0.997	0.000
Q44.2 Atresia of bile ducts	0.003	0.997	0.000
Q44.1 Other congenital malformations of gallbladder	0.003	0.997	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q43.7 Persistent cloaca	0.003	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.003	0.997	0.000
Q43.5 Ectopic anus	0.003	0.997	0.000
Q43.4 Duplication of intestine	0.003	0.997	0.000
Q43.2 Other congenital functional disorders of colon	0.003	0.997	0.000
Q43.1 Hirschsprung's disease	0.003	0.997	0.000
R30.0 Dysuria	0.003	0.997	0.000
M24.57 Contracture of joint (Ankle and foot)	0.003	0.997	0.000
Q12.0 Congenital cataract	0.000	0.997	0.003
M24.26 Disorder of ligament (Lower leg)	0.003	0.997	0.000
Q40.1 Congenital hiatus hernia	0.003	0.997	0.000
X50.4 Street and highway	0.000	0.997	0.003
M24.56 Contracture of joint (Lower leg)	0.003	0.997	0.000
Q45.8 Other specified congenital malformations of digestive system	0.003	0.997	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.003	0.997	0.000
Q38.1 Ankyloglossia	0.003	0.997	0.000
M22 Disorders of patella	0.003	0.997	0.000
M24.0 Loose body in joint	0.003	0.997	0.000
M24.01 Loose body in joint (Shoulder region)	0.003	0.997	0.000
Q38.7 Pharyngeal pouch	0.003	0.997	0.000
R87.7 Abnormal histological findings	0.000	0.997	0.003
M22.4 Chondromalacia patellae	0.003	0.997	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.997	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.997	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.997	0.000
Q45.1 Annular pancreas	0.002	0.997	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.997	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M24.59 Contracture of joint (Site unspecified)	0.002	0.997	0.000
M24.58 Contracture of joint (Other)	0.002	0.997	0.000
M24.53 Contracture of joint (Forearm)	0.002	0.997	0.000
M24.50 Contracture of joint (Multiple sites)	0.002	0.997	0.000
G30.0 Alzheimer's disease with early onset	0.003	0.997	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.003	0.997	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.997	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.997	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.003	0.997	0.000
Q40.2 Other specified congenital malformations of stomach	0.002	0.997	0.000
K83.1 Obstruction of bile duct	0.003	0.997	0.000
Q38.8 Other congenital malformations of pharynx	0.002	0.997	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.002	0.997	0.000
Q38.3 Other congenital malformations of tongue	0.002	0.997	0.000
Q38.2 Macroglossia	0.002	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.002	0.997	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.002	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.002	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.002	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.002	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.002	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.002	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.002	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.002	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.002	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.002	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.002	0.998	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.998	0.000
M22.0 Recurrent dislocation of patella	0.002	0.998	0.000
M24.2 Disorder of ligament	0.002	0.998	0.000
M24 Other specific joint derangements	0.002	0.998	0.000
M24.07 Loose body in joint (Ankle and foot)	0.002	0.998	0.000
C22.1 Intrahepatic bile duct carcinoma	0.000	0.998	0.002
M24.52 Contracture of joint (Upper arm)	0.002	0.998	0.000
G30.9 Alzheimer's disease, unspecified	0.002	0.998	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.002	0.998	0.000
M24.03 Loose body in joint (Forearm)	0.002	0.998	0.000
C71.2 Temporal lobe	0.000	0.998	0.002
M24.7 Protrusio acetabuli	0.002	0.998	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.002	0.998	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.002	0.998	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.002	0.998	0.000
M24.21 Disorder of ligament (Shoulder region)	0.002	0.998	0.000
N60.1 Diffuse cystic mastopathy	0.000	0.998	0.002
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.002	0.998	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.002	0.998	0.000
M24.02 Loose body in joint (Upper arm)	0.002	0.998	0.000
M22.1 Recurrent subluxation of patella	0.002	0.998	0.000
M24.6 Ankylosis of joint	0.002	0.998	0.000
M24.09 Loose body in joint (Site unspecified)	0.002	0.998	0.000
M24.08 Loose body in joint (Other)	0.002	0.998	0.000
M24.00 Loose body in joint (Multiple sites)	0.002	0.998	0.000
Q38.6 Other congenital malformations of mouth	0.002	0.998	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.002	0.998	0.000
M24.64 Ankylosis of joint (Hand)	0.002	0.998	0.000
M22.3 Other derangements of patella	0.002	0.998	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.000	0.998	0.002
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M24.06 Loose body in joint-Lower leg	0.002	0.998	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.002	0.998	0.000
I65.2 Occlusion and stenosis of carotid artery	0.002	0.998	0.000
M24.24 Disorder of ligament (Hand)	0.002	0.998	0.000
M24.51 Contracture of joint (Shoulder region)	0.002	0.998	0.000
M24.9 Joint derangement, unspecified	0.002	0.998	0.000
M24.04 Loose body in joint (Hand)	0.002	0.998	0.000
M24.29 Disorder of ligament (Site unspecified)	0.002	0.998	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.002	0.998	0.000
M24.22 Disorder of ligament (Upper arm)	0.002	0.998	0.000
M24.20 Disorder of ligament (Multiple sites)	0.002	0.998	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
M22.9 Disorder of patella, unspecified	0.002	0.998	0.000
G30 Alzheimer's disease	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.002	0.998	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.002	0.998	0.000
M94.88 Other specified disorders of cartilage (Other)	0.002	0.998	0.000
D25.0 Submucous leiomyoma of uterus	0.000	0.998	0.002
S72.30 Fracture of shaft of femur (closed)	0.000	0.998	0.002
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
M24.79 Protrusio acetabuli-Site unspec	0.002	0.998	0.000
M24.78 Protrusio acetabuli-Other	0.002	0.998	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.002	0.998	0.000
M24.76 Protrusio acetabuli-Lower leg	0.002	0.998	0.000
M24.74 Protrusio acetabuli-Hand	0.002	0.998	0.000
M24.73 Protrusio acetabuli-Forearm	0.002	0.998	0.000
M24.72 Protrusio acetabuli-Upper arm	0.002	0.998	0.000
M24.71 Protrusio acetabuli-Shldr region	0.002	0.998	0.000
M24.70 Protrusio acetabuli-Mult sites	0.002	0.998	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.002	0.998	0.000
M22.2 Patellofemoral disorders	0.002	0.998	0.000
R05 Cough	0.002	0.998	0.000
T78.3 Angioneurotic oedema	0.002	0.998	0.000
H02.5 Other disorders affecting eyelid function	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.002	0.998	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.002	0.998	0.000
M24.68 Ankylosis of joint (Other)	0.002	0.998	0.000
M24.63 Ankylosis of joint (Forearm)	0.002	0.998	0.000
M24.62 Ankylosis of joint (Upper arm)	0.002	0.998	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.002	0.998	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.002	0.998	0.000
Y83.3 Surgical operation with formation of external stoma	0.000	0.998	0.002
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.002	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
S82.40 Fracture of fibula alone (closed)	0.000	0.998	0.002
O75.8 Other specified complications of labour and delivery	0.000	0.998	0.002
X50 Overexertion and strenuous or repetitive movements	0.000	0.998	0.002
M24.66 Ankylosis of joint (Lower leg)	0.002	0.998	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
G30.1 Alzheimer's disease with late onset	0.002	0.998	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
M24.96 Joint derangement, unspecified (Lower leg)	0.002	0.998	0.000
X50.2 School, other institution and public administrative area	0.000	0.998	0.002
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.002	0.998	0.000
M24.98 Joint derangement, unspecified (Other)	0.002	0.998	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.002	0.998	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M24.94 Joint derangement, unspecified (Hand)	0.002	0.998	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.002	0.998	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.002	0.998	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.002	0.998	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
C16.9 Stomach, unspecified	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.000	0.998	0.002
D10.3 Other and unspecified parts of mouth	0.000	0.998	0.002
F33.9 Recurrent depressive disorder, unspecified	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.000	0.998	0.002
F33.1 Recurrent depressive disorder, current episode moderate	0.002	0.998	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.001	0.998	0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.000	0.998	0.002
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.002	0.998	0.000
T88.4 Failed or difficult intubation	0.002	0.998	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.002	0.998	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.002	0.998	0.000
M24.28 Disorder of ligament (Other)	0.001	0.998	0.000
Q12 Congenital lens malformations	0.000	0.998	0.002
M24.23 Disorder of ligament (Forearm)	0.001	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.998	0.002
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.002	0.998	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.998	0.002
J37.0 Chronic laryngitis	0.002	0.998	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.998	0.002
X50.9 Unspecified place	0.000	0.998	0.001
X50.8 Other specified place	0.000	0.998	0.001
X50.5 Trade and service area	0.000	0.998	0.001
X50.3 Sports and athletics area	0.000	0.998	0.001
X50.0 Home	0.000	0.998	0.001
X50.7 Farm	0.000	0.998	0.001
X50.1 Residential institution	0.000	0.998	0.001
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.998	0.002
C32.0 Glottis	0.002	0.998	0.000
X50.6 Industrial and construction area	0.000	0.998	0.001
T78 Adverse effects, not elsewhere classified	0.002	0.998	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.001	0.998	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.001	0.998	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.001	0.998	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.002	0.998	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.001	0.998	0.000
S52.20 Fracture of shaft of ulna (closed)	0.000	0.998	0.002
G30.8 Other Alzheimer's disease	0.001	0.998	0.000
Z09.8 Follow-up examination after other treatment for other conditions	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.001	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.001	0.998	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.002	0.998	0.000
H93.1 Tinnitus	0.000	0.998	0.002
K08.2 Atrophy of edentulous alveolar ridge	0.001	0.998	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.999	0.001
J04.0 Acute laryngitis	0.001	0.999	0.000
M92.7 Juvenile osteochondrosis of metatarsus	0.000	0.999	0.001
R50.1 Persistent fever	0.000	0.999	0.001
F33 Recurrent depressive disorder	0.001	0.999	0.000
D02.2 Bronchus and lung	0.001	0.999	0.000
Q12.9 Congenital lens malformation, unspecified	0.000	0.999	0.001
Q12.8 Other congenital lens malformations	0.000	0.999	0.001
Q12.4 Spherophakia	0.000	0.999	0.001
Q12.3 Congenital aphakia	0.000	0.999	0.001
Q12.2 Coloboma of lens	0.000	0.999	0.001
Q12.1 Congenital displaced lens	0.000	0.999	0.001
H70 Mastoiditis and related conditions	0.000	0.999	0.001
X50.09 Overexertion and strenuous or repetitive movements; Home; During unspecified activity	0.000	0.999	0.001
X50.04 Overexertion and strenuous or repetitive movements; Home; While resting, sleeping, eating or engaging in other vital activities	0.000	0.999	0.001
X50.30 Overexertion and strenuous or repetitive movements; Sports and athletics area;While engaged in sports activity	0.000	0.999	0.001
X50.52 Overexertion and strenuous or repetitive movements, Trade and service area, While working for income	0.000	0.999	0.001
X50.89 Overexertion and strenuous or repetitive movements: Other specified places: During unspecified activity	0.000	0.999	0.001
X50.82 Overexertion and strenuous or repetitive movements; Other specified places ;While working for income	0.000	0.999	0.001
X50.99 Overexertion and strenuous or repetitive movements; Unspecified place ;During unspecified activity	0.000	0.999	0.001
X50.90 Overexertion and strenuous or repetitive movements: Unspecified place: While engaged in sports activity	0.000	0.999	0.001
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.999	0.001
I81 Portal vein thrombosis	0.001	0.999	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations