TreeWAS – Variant ID: rs1610663

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	1.000	0.000	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
K51 Ulcerative colitis	0.000	0.000	1.000
R31 Unspecified haematuria	0.000	0.005	0.995
E83.1 Disorders of iron metabolism	0.000	0.006	0.994
K51.2 Ulcerative (chronic) proctitis	0.000	0.019	0.981
K51.5 Mucosal proctocolitis	0.000	0.031	0.969
K51.8 Other ulcerative colitis	0.000	0.032	0.968
L40 Psoriasis	0.958	0.042	0.000
L40.5 Arthropathic psoriasis	0.935	0.065	0.000
K51.4 Pseudopolyposis of colon	0.000	0.087	0.913
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.112	0.888
E10 Insulin-dependent diabetes mellitus	0.870	0.130	0.000
E10-E14 Diabetes mellitus	0.863	0.137	0.000
E10.3 With ophthalmic complications	0.859	0.141	0.000
E10.9 Without complications	0.851	0.149	0.000
L40.0 Psoriasis vulgaris	0.842	0.158	0.000
E10.2 With renal complications	0.826	0.174	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.177	0.823
E14 Unspecified diabetes mellitus	0.806	0.194	0.000
E11 Non-insulin-dependent diabetes mellitus	0.793	0.207	0.000
K50-K52 Noninfective enteritis and colitis	0.000	0.208	0.792
E11.9 Without complications	0.781	0.219	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.220	0.780
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.228	0.771
E13 Other specified diabetes mellitus	0.771	0.229	0.000
K50.9 Crohn's disease, unspecified	0.000	0.237	0.763
L40.3 Pustulosis palmaris et plantaris	0.739	0.260	0.000
E14.9 Without complications	0.737	0.263	0.000
L40.1 Generalised pustular psoriasis	0.715	0.285	0.000
K50.1 Crohn's disease of large intestine	0.000	0.295	0.705
L40.4 Guttate psoriasis	0.696	0.304	0.000
L40.2 Acrodermatitis continua	0.687	0.313	0.000
E14.5 With peripheral circulatory complications	0.685	0.315	0.000
R30-R39 Symptoms and signs involving the urinary system	0.000	0.319	0.681
R39 Other symptoms and signs involving the urinary system	0.000	0.321	0.679
E11.7 With multiple complications	0.673	0.327	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.000	0.332	0.668
Chapter IV Endocrine, nutritional and metabolic diseases	0.663	0.337	0.000
E11.1 With ketoacidosis	0.662	0.338	0.000
E13.9 Without complications	0.658	0.342	0.000
E50-E64 Other nutritional deficiencies	0.652	0.348	0.000
E13.3 With ophthalmic complications	0.644	0.356	0.000
E14.1 With ketoacidosis	0.643	0.357	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.639	0.361	0.000
R39.1 Other difficulties with micturition	0.000	0.361	0.639
E05.0 Thyrotoxicosis with diffuse goitre	0.637	0.363	0.000
E00-E07 Disorders of thyroid gland	0.630	0.370	0.000
E10.7 With multiple complications	0.624	0.375	0.000
E10.1 With ketoacidosis	0.621	0.379	0.000
E55 Vitamin D deficiency	0.619	0.381	0.000
E12 Malnutrition-related diabetes mellitus	0.619	0.381	0.000
E05.9 Thyrotoxicosis, unspecified	0.606	0.394	0.000
E14.3 With ophthalmic complications	0.601	0.399	0.000
E55.9 Vitamin D deficiency, unspecified	0.596	0.404	0.000
K50.8 Other Crohn's disease	0.000	0.412	0.588
R35 Polyuria	0.000	0.413	0.587
E10.0 With coma	0.585	0.414	0.000
E53 Deficiency of other B group vitamins	0.578	0.422	0.000
E14.7 With multiple complications	0.578	0.422	0.000
E14.0 With coma	0.578	0.422	0.000
E11.8 With unspecified complications	0.575	0.425	0.000
E14.2 Withrenal complications	0.570	0.430	0.000
E10.6 With other specified complications	0.568	0.432	0.000
E14.8 With unspecified complications	0.563	0.437	0.000
E10.8 With unspecified complications	0.559	0.441	0.000
E11.5 With peripheral circulatory complications	0.557	0.443	0.000
E13.8 With unspecified complications	0.553	0.447	0.000
E13.7 With multiple complications	0.553	0.447	0.000
E13.6 With other specified complications	0.553	0.447	0.000
E13.5 With peripheral circulatory complications	0.553	0.447	0.000
E13.4 With neurological complications	0.553	0.447	0.000
E13.2 With renal complications	0.553	0.447	0.000
E13.1 With ketoacidosis	0.553	0.447	0.000
E13.0 With coma	0.553	0.447	0.000
E14.4 With neurological complications	0.547	0.452	0.000
K90 Intestinal malabsorption	0.547	0.453	0.000
E53.8 Deficiency of other specified B group vitamins	0.543	0.457	0.000
E11.0 With coma	0.541	0.459	0.000
E11.2 With renal complications	0.537	0.463	0.000
L40.8 Other psoriasis	0.526	0.474	0.000
E10.4 With neurological complications	0.520	0.479	0.000
E61 Deficiency of other nutrient elements	0.520	0.480	0.000
E11.6 With other specified complications	0.508	0.492	0.000
R39.2 Extrarenal uraemia	0.000	0.513	0.487
E14.6 With other specified complications	0.483	0.517	0.000
E10.5 With peripheral circulatory complications	0.478	0.522	0.000
R36 Urethral discharge	0.000	0.522	0.478
E51 Thiamine deficiency	0.475	0.525	0.000
E58 Dietary calcium deficiency	0.475	0.525	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.470	0.530	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.467	0.532	0.000
E63 Other nutritional deficiencies	0.467	0.532	0.000
E50 Vitamin A deficiency	0.467	0.532	0.000
E60 Dietary zinc deficiency	0.467	0.532	0.000
E59 Dietary selenium deficiency	0.467	0.532	0.000
E54 Ascorbic acid deficiency	0.467	0.532	0.000
E52 Niacin deficiency [pellagra]	0.467	0.532	0.000
E20-E35 Disorders of other endocrine glands	0.466	0.534	0.000
E56 Other vitamin deficiencies	0.464	0.536	0.000
E05.5 Thyroid crisis or storm	0.458	0.542	0.000
E05.4 Thyrotoxicosis factitia	0.458	0.542	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.458	0.542	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.458	0.542	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.452	0.548	0.000
E00 Congenital iodine-deficiency syndrome	0.452	0.548	0.000
R39.0 Extravasation of urine	0.000	0.552	0.448
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.446	0.553	0.000
E23 Hypofunction and other disorders of pituitary gland	0.446	0.554	0.000
E55.0 Rickets, active	0.444	0.556	0.000
E12.9 Without complications	0.444	0.556	0.000
E12.8 With unspecified complications	0.444	0.556	0.000
E12.7 With multiple complications	0.444	0.556	0.000
E12.6 With other specified complications	0.444	0.556	0.000
E12.5 With peripheral circulatory complications	0.444	0.556	0.000
E12.4 With neurological complications	0.444	0.556	0.000
E12.3 With ophthalmic complications	0.444	0.556	0.000
E12.2 With renal complications	0.444	0.556	0.000
E12.1 With ketoacidosis	0.444	0.556	0.000
E12.0 With coma	0.444	0.556	0.000
E05.8 Other thyrotoxicosis	0.443	0.557	0.000
K90.8 Other intestinal malabsorption	0.443	0.557	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.437	0.563	0.000
K90.9 Intestinal malabsorption, unspecified	0.431	0.569	0.000
E23.2 Diabetes insipidus	0.420	0.580	0.000
E61.1 Iron deficiency	0.416	0.584	0.000
E53.1 Pyridoxine deficiency	0.414	0.585	0.000
E53.0 Riboflavin deficiency	0.414	0.585	0.000
R30 Pain associated with micturition	0.000	0.595	0.405
K90.3 Pancreatic steatorrhoea	0.392	0.608	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.392	0.608	0.000
K90.1 Tropical sprue	0.392	0.608	0.000
E61.2 Magnesium deficiency	0.385	0.615	0.000
E27 Other disorders of adrenal gland	0.378	0.622	0.000
E23.0 Hypopituitarism	0.376	0.624	0.000
E61.9 Deficiency of nutrient element, unspecified	0.373	0.627	0.000
E61.8 Deficiency of other specified nutrient elements	0.373	0.627	0.000
E61.7 Deficiency of multiple nutrient elements	0.373	0.627	0.000
E61.6 Vanadium deficiency	0.373	0.627	0.000
E61.5 Molybdenum deficiency	0.373	0.627	0.000
E61.4 Chromium deficiency	0.373	0.627	0.000
E61.3 Manganese deficiency	0.373	0.627	0.000
E61.0 Copper deficiency	0.373	0.627	0.000
E40-E46 Malnutrition	0.365	0.635	0.000
K50.0 Crohn's disease of small intestine	0.000	0.645	0.355
E27.1 Primary adrenocortical insufficiency	0.351	0.649	0.000
E51.2 Wernicke's encephalopathy	0.348	0.652	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.348	0.652	0.000
E07 Other disorders of thyroid	0.347	0.653	0.000
E28 Ovarian dysfunction	0.346	0.654	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.346	0.654	0.000
E51.9 Thiamine deficiency, unspecified	0.341	0.659	0.000
E51.8 Other manifestations of thiamine deficiency	0.341	0.659	0.000
E51.1 Beriberi	0.341	0.659	0.000
E50.9 Vitamin A deficiency, unspecified	0.335	0.665	0.000
E50.8 Other manifestations of vitamin A deficiency	0.335	0.665	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.335	0.665	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.335	0.665	0.000
E50.5 Vitamin A deficiency with night blindness	0.335	0.665	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.335	0.665	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.335	0.665	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.335	0.665	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.335	0.665	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.335	0.665	0.000
E63.9 Nutritional deficiency, unspecified	0.335	0.665	0.000
E63.8 Other specified nutritional deficiencies	0.335	0.665	0.000
E63.1 Imbalance of constituents of food intake	0.335	0.665	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.335	0.665	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.335	0.665	0.000
E64.8 Sequelae of other nutritional deficiencies	0.335	0.665	0.000
E64.3 Sequelae of rickets	0.335	0.665	0.000
E64.2 Sequelae of vitamin C deficiency	0.335	0.665	0.000
E64.1 Sequelae of vitamin A deficiency	0.335	0.665	0.000
E64.0 Sequelae of protein-energy malnutrition	0.335	0.665	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.334	0.666	0.000
E32 Diseases of thymus	0.334	0.666	0.000
E30 Disorders of puberty, not elsewhere classified	0.334	0.666	0.000
E56.9 Vitamin deficiency, unspecified	0.332	0.667	0.000
E56.8 Deficiency of other vitamins	0.332	0.667	0.000
E56.0 Deficiency of vitamin E	0.332	0.667	0.000
E31 Polyglandular dysfunction	0.332	0.667	0.000
E53.9 Vitamin B deficiency, unspecified	0.331	0.669	0.000
E25 Adrenogenital disorders	0.329	0.671	0.000
E56.1 Deficiency of vitamin K	0.329	0.671	0.000
E23.6 Other disorders of pituitary gland	0.327	0.673	0.000
E20 Hypoparathyroidism	0.325	0.675	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.324	0.676	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.324	0.676	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.324	0.676	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.324	0.676	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.324	0.676	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.324	0.676	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.324	0.676	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.324	0.676	0.000
E15 Nondiabetic hypoglycaemic coma	0.320	0.680	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.320	0.680	0.000
E23.1 Drug-induced hypopituitarism	0.320	0.680	0.000
E03 Other hypothyroidism	0.320	0.680	0.000
R30.1 Vesical tenesmus	0.000	0.681	0.319
E23.7 Disorder of pituitary gland, unspecified	0.315	0.685	0.000
E24 Cushing's syndrome	0.311	0.689	0.000
E26 Hyperaldosteronism	0.309	0.691	0.000
E06 Thyroiditis	0.302	0.697	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.300	0.699	0.000
R30.0 Dysuria	0.000	0.708	0.292
E16 Other disorders of pancreatic internal secretion	0.291	0.709	0.000
E21.0 Primary hyperparathyroidism	0.291	0.709	0.000
E28.3 Primary ovarian failure	0.291	0.709	0.000
R34 Anuria and oliguria	0.000	0.721	0.278
E27.3 Drug-induced adrenocortical insufficiency	0.275	0.724	0.000
E27.5 Adrenomedullary hyperfunction	0.271	0.729	0.000
E27.0 Other adrenocortical overactivity	0.271	0.729	0.000
E21.2 Other hyperparathyroidism	0.264	0.736	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.261	0.738	0.000
E45 Retarded development following protein-energy malnutrition	0.261	0.738	0.000
E43 Unspecified severe protein-energy malnutrition	0.261	0.738	0.000
E42 Marasmic kwashiorkor	0.261	0.738	0.000
E41 Nutritional marasmus	0.261	0.738	0.000
E40 Kwashiorkor	0.261	0.738	0.000
E21.4 Other specified disorders of parathyroid gland	0.259	0.741	0.000
E24.0 Pituitary-dependent Cushing's disease	0.256	0.744	0.000
E29 Testicular dysfunction	0.252	0.747	0.000
E27.2 Addisonian crisis	0.250	0.750	0.000
E07.1 Dyshormogenetic goitre	0.249	0.751	0.000
E07.0 Hypersecretion of calcitonin	0.249	0.751	0.000
E28.9 Ovarian dysfunction, unspecified	0.248	0.752	0.000
E28.8 Other ovarian dysfunction	0.248	0.752	0.000
E28.1 Androgen excess	0.248	0.752	0.000
E28.0 Oestrogen excess	0.248	0.752	0.000
E07.8 Other specified disorders of thyroid	0.246	0.754	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.245	0.755	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.240	0.760	0.000
E30.9 Disorder of puberty, unspecified	0.240	0.760	0.000
E30.8 Other disorders of puberty	0.240	0.760	0.000
E30.1 Precocious puberty	0.240	0.760	0.000
E30.0 Delayed puberty	0.240	0.760	0.000
E32.9 Disease of thymus, unspecified	0.240	0.760	0.000
E32.8 Other diseases of thymus	0.240	0.760	0.000
E32.1 Abscess of thymus	0.240	0.760	0.000
E32.0 Persistent hyperplasia of thymus	0.240	0.760	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.240	0.760	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.240	0.760	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.240	0.760	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.239	0.760	0.000
E31.9 Polyglandular dysfunction, unspecified	0.238	0.761	0.000
E31.8 Other polyglandular dysfunction	0.238	0.761	0.000
E31.1 Polyglandular hyperfunction	0.238	0.761	0.000
E03.1 Congenital hypothyroidism without goitre	0.237	0.762	0.000
E06.9 Thyroiditis, unspecified	0.237	0.763	0.000
E31.0 Autoimmune polyglandular failure	0.237	0.763	0.000
E25.9 Adrenogenital disorder, unspecified	0.236	0.764	0.000
E25.8 Other adrenogenital disorders	0.236	0.764	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.236	0.764	0.000
E20.8 Other hypoparathyroidism	0.233	0.767	0.000
E20.1 Pseudohypoparathyroidism	0.233	0.767	0.000
E20.0 Idiopathic hypoparathyroidism	0.233	0.767	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.231	0.769	0.000
E03.5 Myxoedema coma	0.229	0.771	0.000
E03.4 Atrophy of thyroid (acquired)	0.229	0.771	0.000
E03.3 Postinfectious hypothyroidism	0.229	0.771	0.000
E03.8 Other specified hypothyroidism	0.229	0.771	0.000
E24.2 Drug-induced Cushing's syndrome	0.228	0.772	0.000
E26.9 Hyperaldosteronism, unspecified	0.227	0.773	0.000
E20.9 Hypoparathyroidism, unspecified	0.223	0.777	0.000
E24.8 Other Cushing's syndrome	0.223	0.777	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.223	0.777	0.000
E24.3 Ectopic ACTH syndrome	0.223	0.777	0.000
E24.1 Nelson's syndrome	0.223	0.777	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.222	0.778	0.000
E16.1 Other hypoglycaemia	0.222	0.778	0.000
E26.8 Other hyperaldosteronism	0.221	0.778	0.000
E26.1 Secondary hyperaldosteronism	0.221	0.778	0.000
E11.3 With ophthalmic complications	0.221	0.779	0.000
E06.4 Drug-induced thyroiditis	0.217	0.783	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.217	0.783	0.000
E06.0 Acute thyroiditis	0.217	0.783	0.000
E06.1 Subacute thyroiditis	0.216	0.784	0.000
L40-L45 Papulosquamous disorders	0.211	0.789	0.000
E21.3 Hyperparathyroidism, unspecified	0.210	0.790	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.209	0.791	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.209	0.791	0.000
E16.4 Abnormal secretion of gastrin	0.209	0.791	0.000
E16.3 Increased secretion of glucagon	0.209	0.791	0.000
E27.8 Other specified disorders of adrenal gland	0.199	0.800	0.000
E27.9 Disorder of adrenal gland, unspecified	0.197	0.803	0.000
E06.5 Other chronic thyroiditis	0.196	0.803	0.000
E28.2 Polycystic ovarian syndrome	0.194	0.806	0.000
E34 Other endocrine disorders	0.192	0.807	0.000
E26.0 Primary hyperaldosteronism	0.189	0.811	0.000
E44.1 Mild protein-energy malnutrition	0.188	0.812	0.000
E44.0 Moderate protein-energy malnutrition	0.188	0.812	0.000
E29.9 Testicular dysfunction, unspecified	0.181	0.819	0.000
E29.8 Other testicular dysfunction	0.181	0.819	0.000
E29.0 Testicular hyperfunction	0.181	0.819	0.000
E11.4 With neurological complications	0.169	0.831	0.000
E65-E68 Obesity and other hyperalimentation	0.154	0.846	0.001
L44 Other papulosquamous disorders	0.152	0.848	0.000
L41 Parapsoriasis	0.152	0.848	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.152	0.848	0.000
E46 Unspecified protein-energy malnutrition	0.150	0.849	0.000
E07.9 Disorder of thyroid, unspecified	0.148	0.851	0.000
E22 Hyperfunction of pituitary gland	0.148	0.852	0.000
R33 Retention of urine	0.000	0.857	0.143
E34.5 Androgen resistance syndrome	0.138	0.862	0.000
E34.4 Constitutional tall stature	0.138	0.862	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.138	0.862	0.000
E34.1 Other hypersecretion of intestinal hormones	0.138	0.862	0.000
R30.9 Painful micturition, unspecified	0.001	0.863	0.136
E34.3 Short stature, not elsewhere classified	0.136	0.864	0.000
L42 Pityriasis rosea	0.130	0.870	0.000
E24.9 Cushing's syndrome, unspecified	0.121	0.878	0.001
E34.8 Other specified endocrine disorders	0.114	0.885	0.000
E34.9 Endocrine disorder, unspecified	0.112	0.888	0.000
E67 Other hyperalimentation	0.110	0.889	0.001
E68 Sequelae of hyperalimentation	0.110	0.889	0.001
L41.9 Parapsoriasis, unspecified	0.109	0.891	0.000
L41.8 Other parapsoriasis	0.109	0.891	0.000
L41.5 Retiform parapsoriasis	0.109	0.891	0.000
L41.4 Large plaque parapsoriasis	0.109	0.891	0.000
L41.3 Small plaque parapsoriasis	0.109	0.891	0.000
L41.2 Lymphomatoid papulosis	0.109	0.891	0.000
L41.1 Pityriasis lichenoides chronica	0.109	0.891	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.109	0.891	0.000
L44.9 Papulosquamous disorder, unspecified	0.109	0.891	0.000
L44.8 Other specified papulosquamous disorders	0.109	0.891	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.109	0.891	0.000
L44.3 Lichen ruber moniliformis	0.109	0.891	0.000
L44.2 Lichen striatus	0.109	0.891	0.000
L44.1 Lichen nitidus	0.109	0.891	0.000
L44.0 Pityriasis rubra pilaris	0.109	0.891	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.106	0.893	0.000
E22.8 Other hyperfunction of pituitary gland	0.106	0.893	0.000
E34.0 Carcinoid syndrome	0.104	0.895	0.000
E29.1 Testicular hypofunction	0.099	0.900	0.000
L43 Lichen planus	0.096	0.904	0.000
E16.2 Hypoglycaemia, unspecified	0.093	0.907	0.000
K52 Other non-infective gastro-enteritis and colitis	0.000	0.909	0.090
E83 Disorders of mineral metabolism	0.002	0.913	0.085
N13 Obstructive and reflux uropathy	0.086	0.914	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.084	0.916	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.083	0.917	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.082	0.918	0.000
E67.8 Other specified hyperalimentation	0.079	0.920	0.001
E67.3 Hypervitaminosis D	0.079	0.920	0.001
E67.2 Megavitamin-B6 syndrome	0.079	0.920	0.001
E67.1 Hypercarotenaemia	0.079	0.920	0.001
E67.0 Hypervitaminosis A	0.079	0.920	0.001
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.079	0.921	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.921	0.079
E22.1 Hyperprolactinaemia	0.074	0.926	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.074	0.926	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.073	0.927	0.000
E22.0 Acromegaly and pituitary gigantism	0.071	0.929	0.000
N13.4 Hydroureter	0.071	0.929	0.000
L43.3 Subacute (active) lichen planus	0.069	0.931	0.000
L43.2 Lichenoid drug reaction	0.069	0.931	0.000
L43.1 Bullous lichen planus	0.069	0.931	0.000
L43.0 Hypertrophic lichen planus	0.069	0.931	0.000
N13.6 Pyonephrosis	0.067	0.933	0.000
L43.8 Other lichen planus	0.066	0.934	0.000
J45.9 Asthma, unspecified	0.064	0.936	0.000
E83.8 Other disorders of mineral metabolism	0.001	0.937	0.061
E83.2 Disorders of zinc metabolism	0.001	0.937	0.061
E83.0 Disorders of copper metabolism	0.001	0.937	0.061
N11 Chronic tubulo-interstitial nephritis	0.061	0.939	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.940	0.060
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.060	0.940	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.001	0.940	0.058
N10-N16 Renal tubulo-interstitial diseases	0.059	0.941	0.000
E06.3 Autoimmune thyroiditis	0.057	0.942	0.001
B02.9 Zoster without complication	0.058	0.942	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.947	0.053
N11.1 Chronic obstructive pyelonephritis	0.052	0.948	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.051	0.949	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.050	0.949	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.049	0.950	0.000
K52.3 Indeterminate colitis	0.000	0.951	0.048
E83.3 Disorders of phosphorus metabolism	0.001	0.953	0.046
K90-K93 Other diseases of the digestive system	0.047	0.953	0.000
K52.1 Toxic gastro-enteritis and colitis	0.000	0.955	0.044
N11.8 Other chronic tubulo-interstitial nephritis	0.044	0.956	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.043	0.957	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.042	0.957	0.000
R32 Unspecified urinary incontinence	0.000	0.958	0.042
N81.2 Incomplete uterovaginal prolapse	0.000	0.959	0.041
E65 Localised adiposity	0.037	0.961	0.002
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.962	0.038
N15 Other renal tubulo-interstitial diseases	0.036	0.964	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.036	0.964	0.000
N14.3 Nephropathy induced by heavy metals	0.036	0.964	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.036	0.964	0.000
N14.0 Analgesic nephropathy	0.036	0.964	0.000
E04 Other non-toxic goitre	0.034	0.966	0.001
K93 Disorders of other digestive organs in diseases classified elsewhere	0.034	0.966	0.000
K62.8 Other specified diseases of anus and rectum	0.000	0.968	0.032
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.031	0.969	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.031	0.969	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.031	0.969	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.031	0.969	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.031	0.969	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.031	0.969	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.031	0.969	0.000
B02 Zoster [herpes zoster]	0.031	0.969	0.000
N13.8 Other obstructive and reflux uropathy	0.028	0.972	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.026	0.974	0.000
N15.0 Balkan nephropathy	0.026	0.974	0.000
E04.8 Other specified non-toxic goitre	0.024	0.975	0.001
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.025	0.975	0.000
K93.1 Megacolon in Chagas' disease	0.025	0.975	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.025	0.975	0.000
B02.1 Zoster meningitis	0.024	0.976	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.024	0.976	0.000
B02.8 Zoster with other complications	0.024	0.976	0.000
N10 Acute tubulo-interstitial nephritis	0.023	0.977	0.000
N15.1 Renal and perinephric abscess	0.023	0.977	0.000
B02.2 Zoster with other nervous system involvement	0.022	0.978	0.000
B02.7 Disseminated zoster	0.022	0.978	0.000
B02.0 Zoster encephalitis	0.022	0.978	0.000
L43.9 Lichen planus, unspecified	0.022	0.978	0.000
G56.0 Carpal tunnel syndrome	0.021	0.979	0.000
E04.0 Non-toxic diffuse goitre	0.018	0.982	0.001
I83 Varicose veins of lower extremities	0.000	0.982	0.018
B02.3 Zoster ocular disease	0.018	0.982	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.018	0.982	0.000
E66 Obesity	0.017	0.983	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.984	0.016
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.985	0.015
J45 Asthma	0.014	0.986	0.000
W13.9 Unspecified place	0.014	0.986	0.000
K91.1 Postgastric surgery syndromes	0.014	0.986	0.000
K91.5 Postcholecystectomy syndrome	0.014	0.986	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.013	0.987	0.000
E66.1 Drug-induced obesity	0.012	0.987	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.013	0.987	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.012	0.988	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.012	0.988	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.011	0.989	0.000
L73.2 Hidradenitis suppurativa	0.000	0.989	0.011
J45.8 Mixed asthma	0.011	0.989	0.000
J45.1 Nonallergic asthma	0.011	0.989	0.000
E70-E90 Metabolic disorders	0.009	0.989	0.002
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.011	0.989	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.009	0.991	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.009	0.991	0.000
E66.0 Obesity due to excess calories	0.008	0.991	0.000
E83.5 Disorders of calcium metabolism	0.001	0.991	0.008
K91.3 Postoperative intestinal obstruction	0.008	0.992	0.000
E84 Cystic fibrosis	0.006	0.992	0.002
E77 Disorders of glycoprotein metabolism	0.006	0.992	0.002
E76 Disorders of glycosaminoglycan metabolism	0.006	0.992	0.002
E72 Other disorders of amino-acid metabolism	0.006	0.992	0.002
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.006	0.992	0.002
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.006	0.992	0.002
E70 Disorders of aromatic amino-acid metabolism	0.006	0.992	0.002
E73 Lactose intolerance	0.006	0.992	0.001
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.006	0.992	0.002
B00 Herpesviral [herpes simplex] infections	0.008	0.992	0.000
E79 Disorders of purine and pyrimidine metabolism	0.006	0.992	0.002
E78.2 Mixed hyperlipidaemia	0.008	0.992	0.000
E88 Other metabolic disorders	0.007	0.993	0.001
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.007	0.993	0.000
E74 Other disorders of carbohydrate metabolism	0.006	0.993	0.002
B01 Varicella [chickenpox]	0.007	0.993	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.002	0.993	0.005
E04.9 Non-toxic goitre, unspecified	0.007	0.993	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.007	0.993	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.007	0.993	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.007	0.993	0.000
B06 Rubella [German measles]	0.007	0.993	0.000
B05 Measles	0.007	0.993	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.007	0.993	0.000
B04 Monkeypox	0.007	0.993	0.000
B03 Smallpox	0.007	0.993	0.000
E04.2 Non-toxic multinodular goitre	0.007	0.993	0.000
E03.9 Hypothyroidism, unspecified	0.007	0.993	0.000
N13.3 Other and unspecified hydronephrosis	0.007	0.993	0.000
E88.2 Lipomatosis, not elsewhere classified	0.006	0.993	0.000
L94.0 Localised scleroderma [morphea]	0.007	0.993	0.000
L94 Other localised connective tissue disorders	0.007	0.993	0.000
B00.8 Other forms of herpesviral infection	0.006	0.994	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.006	0.994	0.000
W13 Fall from, out of or through building or structure	0.006	0.994	0.000
L10-L14 Bullous disorders	0.006	0.994	0.000
E78.4 Other hyperlipidaemia	0.006	0.994	0.000
B00.5 Herpesviral ocular disease	0.006	0.994	0.000
B00.9 Herpesviral infection, unspecified	0.006	0.994	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.006	0.994	0.000
E78.6 Lipoprotein deficiency	0.006	0.994	0.000
L94.2 Calcinosis cutis	0.006	0.994	0.000
B00.1 Herpesviral vesicular dermatitis	0.006	0.994	0.000
E84.9 Cystic fibrosis, unspecified	0.005	0.994	0.001
E84.8 Cystic fibrosis with other manifestations	0.005	0.994	0.001
E84.1 Cystic fibrosis with intestinal manifestations	0.005	0.994	0.001
E84.0 Cystic fibrosis with pulmonary manifestations	0.005	0.994	0.001
E71.3 Disorders of fatty-acid metabolism	0.005	0.994	0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.005	0.994	0.001
E71.1 Other disorders of branched-chain amino-acid metabolism	0.005	0.994	0.001
E71.0 Maple-syrup-urine disease	0.005	0.994	0.001
E72.9 Disorder of amino-acid metabolism, unspecified	0.005	0.994	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations