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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1631281
log Bayes Factor = 9.53385
Chromosome 10   position 123,390,785  (GRCh37) Explore rs1631281 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C50.9 Breast, unspecified
1.000 0.000 0.000
Z85.3 Personal history of malignant neoplasm of breast
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.995 0.005 0.000
M06 Other rheumatoid arthritis
0.991 0.009 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.987 0.013 0.000
M05-M14 Inflammatory polyarthropathies
0.987 0.013 0.000
M25 Other joint disorders, not elsewhere classified
0.985 0.015 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.985 0.015 0.000
M20-M25 Other joint disorders
0.984 0.016 0.000
M25.5 Pain in joint
0.973 0.027 0.000
C50 Malignant neoplasm of breast
0.971 0.029 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.970 0.030 0.000
M24 Other specific joint derangements
0.943 0.057 0.000
M25.0 Haemarthrosis
0.933 0.067 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.925 0.075 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.924 0.076 0.000
M24.1 Other articular cartilage disorders
0.912 0.088 0.000
M80-M85 Disorders of bone density and structure
0.906 0.094 0.000
M86-M90 Other osteopathies
0.902 0.098 0.000
M25.06 Haemarthrosis (Lower leg)
0.897 0.103 0.000
M25.3 Other instability of joint
0.893 0.107 0.000
M21 Other acquired deformities of limbs
0.882 0.118 0.000
C50.5 Lower-outer quadrant of breast
0.876 0.124 0.000
C50.1 Central portion of breast
0.874 0.126 0.000
M25.53 Pain in joint (Forearm)
0.874 0.126 0.000
M05 Seropositive rheumatoid arthritis
0.873 0.127 0.000
M00-M03 Infectious arthropathies
0.860 0.140 0.000
M85 Other disorders of bone density and structure
0.860 0.140 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.859 0.141 0.000
M25.56 Pain in joint (Lower leg)
0.856 0.144 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.846 0.154 0.000
M06.0 Seronegative rheumatoid arthritis
0.840 0.160 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.838 0.162 0.000
C50.0 Nipple and areola
0.837 0.163 0.000
M60-M63 Disorders of muscles
0.833 0.166 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.831 0.169 0.000
M25.9 Joint disorder, unspecified
0.828 0.172 0.000
C50.3 Lower-inner quadrant of breast
0.822 0.178 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.820 0.180 0.000
M25.4 Effusion of joint
0.811 0.189 0.000
M23 Internal derangement of knee
0.810 0.190 0.000
M91-M94 Chondropathies
0.791 0.209 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.790 0.210 0.000
M85.0 Fibrous dysplasia (monostotic)
0.788 0.212 0.000
M87 Osteonecrosis
0.775 0.225 0.000
M24.2 Disorder of ligament
0.774 0.226 0.000
M25.50 Pain in joint (Multiple sites)
0.773 0.227 0.000
M89 Other disorders of bone
0.771 0.229 0.000
M00 Pyogenic arthritis
0.771 0.229 0.000
M24.0 Loose body in joint
0.769 0.231 0.000
M21.1 Varus deformity, not elsewhere classified
0.767 0.232 0.000
M14 Arthropathies in other diseases classified elsewhere
0.765 0.235 0.000
M25.37 Other instability of joint (Ankle and foot)
0.757 0.242 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.757 0.243 0.000
M07 Psoriatic and enteropathic arthropathies
0.754 0.246 0.000
C50.8 Overlapping lesion of breast
0.752 0.248 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.745 0.255 0.000
M25.34 Other instability of joint (Hand)
0.741 0.259 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.739 0.261 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.737 0.263 0.000
M06.3 Rheumatoid nodule
0.732 0.268 0.000
M86 Osteomyelitis
0.729 0.271 0.000
M84 Disorders of continuity of bone
0.726 0.274 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.716 0.284 0.000
M25.47 Effusion of joint (Ankle and foot)
0.716 0.284 0.000
M25.36 Other instability of joint (Lower leg)
0.714 0.286 0.000
M06.8 Other specified rheumatoid arthritis
0.711 0.289 0.000
M06.2 Rheumatoid bursitis
0.711 0.289 0.000
M06.1 Adult-onset Still's disease
0.711 0.289 0.000
M21.4 Flat foot [pes planus] (acquired)
0.710 0.290 0.000
M12 Other specific arthropathies
0.708 0.292 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.708 0.292 0.000
M08 Juvenile arthritis
0.708 0.292 0.000
M00.9 Pyogenic arthritis, unspecified
0.707 0.293 0.000
M25.2 Flail joint
0.706 0.294 0.000
M25.1 Fistula of joint
0.706 0.294 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.706 0.294 0.000
M32 Systemic lupus erythematosus
0.706 0.294 0.000
M30 Polyarteritis nodosa and related conditions
0.706 0.294 0.000
M62 Other disorders of muscle
0.704 0.296 0.000
M23.8 Other internal derangements of knee
0.703 0.297 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.702 0.298 0.000
M65-M68 Disorders of synovium and tendon
0.702 0.298 0.000
M89.9 Disorder of bone, unspecified
0.698 0.302 0.000
M85.9 Disorder of bone density and structure, unspecified
0.697 0.303 0.000
C50.6 Axillary tail of breast
0.696 0.304 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.696 0.304 0.000
M23.0 Cystic meniscus
0.689 0.311 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.689 0.311 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.688 0.312 0.000
M92 Other juvenile osteochondrosis
0.686 0.314 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.685 0.315 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.684 0.315 0.000
M80 Osteoporosis with pathological fracture
0.684 0.316 0.000
M24.24 Disorder of ligament (Hand)
0.677 0.323 0.000
M24.9 Joint derangement, unspecified
0.676 0.324 0.000
M24.7 Protrusio acetabuli
0.676 0.324 0.000
M24.6 Ankylosis of joint
0.676 0.324 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.676 0.324 0.000
M70-M79 Other soft tissue disorders
0.675 0.325 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.674 0.326 0.000
C50.2 Upper-inner quadrant of breast
0.672 0.328 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.671 0.329 0.000
M25.09 Haemarthrosis (Site unspecified)
0.669 0.331 0.000
M25.08 Haemarthrosis (Other)
0.669 0.331 0.000
M25.07 Haemarthrosis (Ankle and foot)
0.669 0.331 0.000
M25.05 Haemarthrosis (Pelvic region and thigh)
0.669 0.331 0.000
M25.04 Haemarthrosis (Hand)
0.669 0.331 0.000
M25.03 Haemarthrosis (Forearm)
0.669 0.331 0.000
M25.02 Haemarthrosis (Upper arm)
0.669 0.331 0.000
M25.01 Haemarthrosis (Shoulder region)
0.669 0.331 0.000
M25.00 Haemarthrosis (Multiple sites)
0.669 0.331 0.000
M25.7 Osteophyte
0.664 0.336 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.664 0.336 0.000
M33 Dermatopolymyositis
0.663 0.337 0.000
M31 Other necrotising vasculopathies
0.663 0.337 0.000
M21.6 Other acquired deformities of ankle and foot
0.662 0.338 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.660 0.339 0.000
M34 Systemic sclerosis
0.659 0.341 0.000
M85.8 Other specified disorders of bone density and structure
0.658 0.342 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.655 0.345 0.000
M06.4 Inflammatory polyarthropathy
0.655 0.345 0.000
M85.6 Other cyst of bone
0.654 0.346 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.654 0.346 0.000
M24.18 Other articular cartilage disorders (Other)
0.654 0.346 0.000
M24.14 Other articular cartilage disorders (Hand)
0.654 0.346 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.654 0.346 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.654 0.346 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.653 0.347 0.000
M83 Adult osteomalacia
0.650 0.350 0.000
M87.2 Osteonecrosis due to previous trauma
0.649 0.351 0.000
M23.1 Discoid meniscus (congenital)
0.646 0.354 0.000
M25.39 Other instability of joint (Site unspecified)
0.640 0.360 0.000
M25.38 Other instability of joint (Other)
0.640 0.360 0.000
M25.35 Other instability of joint (Pelvic region and thigh)
0.640 0.360 0.000
M25.33 Other instability of joint (Forearm)
0.640 0.360 0.000
M25.32 Other instability of joint (Upper arm)
0.640 0.360 0.000
M25.30 Other instability of joint (Multiple sites)
0.640 0.360 0.000
M82 Osteoporosis in diseases classified elsewhere
0.638 0.361 0.000
M21.7 Unequal limb length (acquired)
0.638 0.362 0.000
M60 Myositis
0.636 0.364 0.000
M25.54 Pain in joint (Hand)
0.636 0.364 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.635 0.365 0.000
M24.5 Contracture of joint
0.633 0.367 0.000
M21.9 Acquired deformity of limb, unspecified
0.632 0.368 0.000
M21.8 Other specified acquired deformities of limbs
0.632 0.368 0.000
M24.02 Loose body in joint (Upper arm)
0.629 0.371 0.000
M21.0 Valgus deformity, not elsewhere classified
0.628 0.372 0.000
M05.8 Other seropositive rheumatoid arthritis
0.626 0.374 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.626 0.374 0.000
M05.2 Rheumatoid vasculitis
0.626 0.374 0.000
M05.1 Rheumatoid lung disease
0.626 0.374 0.000
M05.0 Felty's syndrome
0.626 0.374 0.000
M25.58 Pain in joint (Other)
0.625 0.375 0.000
M23.5 Chronic instability of knee
0.624 0.376 0.000
M93 Other osteochondropathies
0.623 0.377 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.623 0.377 0.000
M24.03 Loose body in joint (Forearm)
0.623 0.377 0.000
M90 Osteopathies in diseases classified elsewhere
0.622 0.378 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.621 0.379 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.619 0.381 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.619 0.381 0.000
M10 Gout
0.617 0.383 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.617 0.383 0.000
M02 Reactive arthropathies
0.617 0.383 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.617 0.383 0.000
M85.5 Aneurysmal bone cyst
0.616 0.384 0.000
M85.4 Solitary bone cyst
0.616 0.384 0.000
M85.3 Osteitis condensans
0.616 0.384 0.000
M85.2 Hyperostosis of skull
0.616 0.384 0.000
M85.1 Skeletal fluorosis
0.616 0.384 0.000
M87.9 Osteonecrosis, unspecified
0.615 0.385 0.000
M21.2 Flexion deformity
0.612 0.388 0.000
M62.8 Other specified disorders of muscle
0.611 0.389 0.000
M11 Other crystal arthropathies
0.610 0.390 0.000
M77 Other enthesopathies
0.609 0.391 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.609 0.391 0.000
M25.31 Other instability of joint (Shoulder region)
0.606 0.394 0.000
M14.6 Neuropathic arthropathy
0.605 0.395 0.000
M25.44 Effusion of joint (Hand)
0.604 0.395 0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.603 0.397 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.602 0.397 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.602 0.397 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.602 0.397 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.602 0.397 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.602 0.397 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.602 0.397 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.602 0.397 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.601 0.399 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.598 0.402 0.000
M61 Calcification and ossification of muscle
0.598 0.402 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.596 0.404 0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.596 0.404 0.000
M92.2 Juvenile osteochondrosis of hand
0.595 0.405 0.000
M86.9 Osteomyelitis, unspecified
0.594 0.406 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.594 0.406 0.000
M25.98 Joint disorder, unspecified (Other)
0.594 0.406 0.000
M25.94 Joint disorder, unspecified (Hand)
0.594 0.406 0.000
M25.93 Joint disorder, unspecified (Forearm)
0.594 0.406 0.000
M25.92 Joint disorder, unspecified (Upper arm)
0.594 0.406 0.000
M25.91 Joint disorder, unspecified (Shoulder region)
0.594 0.406 0.000
M25.90 Joint disorder, unspecified (Multiple sites)
0.594 0.406 0.000
M24.26 Disorder of ligament (Lower leg)
0.593 0.407 0.000
M88 Paget's disease of bone [osteitis deformans]
0.588 0.411 0.000
M07.3 Other psoriatic arthropathies
0.587 0.412 0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.587 0.413 0.000
M24.01 Loose body in joint (Shoulder region)
0.586 0.414 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.585 0.414 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.584 0.416 0.000
M25.52 Pain in joint (Upper arm)
0.584 0.416 0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)
0.582 0.418 0.000
M25.49 Effusion of joint (Site unspecified)
0.582 0.418 0.000
M25.48 Effusion of joint (Other)
0.582 0.418 0.000
M25.43 Effusion of joint (Forearm)
0.582 0.418 0.000
M25.42 Effusion of joint (Upper arm)
0.582 0.418 0.000
M25.41 Effusion of joint (Shoulder region)
0.582 0.418 0.000
M25.40 Effusion of joint (Multiple sites)
0.582 0.418 0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)
0.580 0.419 0.000
M25.8 Other specified joint disorders
0.577 0.423 0.000
M84.4 Pathological fracture, not elsewhere classified
0.576 0.424 0.000
M25.77 Osteophyte (Ankle and foot)
0.570 0.430 0.000
M21.3 Wrist or foot drop (acquired)
0.570 0.430 0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)
0.570 0.430 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.567 0.433 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.567 0.433 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.567 0.433 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.567 0.433 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.567 0.433 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.567 0.433 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.567 0.433 0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)
0.565 0.435 0.000
M85.08 Fibrous dysplasia (monostotic) (Other)
0.565 0.435 0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)
0.565 0.435 0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)
0.565 0.435 0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)
0.565 0.435 0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)
0.565 0.435 0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)
0.565 0.435 0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)
0.565 0.435 0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)
0.565 0.435 0.000
M89.0 Algoneurodystrophy
0.564 0.436 0.000
M40-M43 Deforming dorsopathies
0.562 0.438 0.000
M06.34 Rheumatoid nodule (Hand)
0.561 0.439 0.000
C50.4 Upper-outer quadrant of breast
0.560 0.440 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.560 0.440 0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)
0.559 0.441 0.000
M87.8 Other osteonecrosis
0.555 0.445 0.000
M87.3 Other secondary osteonecrosis
0.555 0.445 0.000
M87.1 Osteonecrosis due to drugs
0.555 0.445 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.555 0.445 0.000
M24.29 Disorder of ligament (Site unspecified)
0.555 0.445 0.000
M24.28 Disorder of ligament (Other)
0.555 0.445 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.555 0.445 0.000
M24.22 Disorder of ligament (Upper arm)
0.555 0.445 0.000
M24.21 Disorder of ligament (Shoulder region)
0.555 0.445 0.000
M24.20 Disorder of ligament (Multiple sites)
0.555 0.445 0.000
M89.6 Osteopathy after poliomyelitis
0.553 0.447 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.553 0.447 0.000
M89.2 Other disorders of bone development and growth
0.553 0.447 0.000
M89.1 Epiphyseal arrest
0.553 0.447 0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents
0.553 0.447 0.000
M00.2 Other streptococcal arthritis and polyarthritis
0.553 0.447 0.000
M00.1 Pneumococcal arthritis and polyarthritis
0.553 0.447 0.000
M00.0 Staphylococcal arthritis and polyarthritis
0.553 0.447 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.551 0.449 0.000
M24.09 Loose body in joint (Site unspecified)
0.551 0.449 0.000
M24.08 Loose body in joint (Other)
0.551 0.449 0.000
M24.06 Loose body in joint-Lower leg
0.551 0.449 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.551 0.449 0.000
M24.04 Loose body in joint (Hand)
0.551 0.449 0.000
M24.00 Loose body in joint (Multiple sites)
0.551 0.449 0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)
0.550 0.450 0.000
M21.18 Varus deformity, not elsewhere classified (Other)
0.550 0.450 0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)
0.550 0.450 0.000
M21.14 Varus deformity, not elsewhere classified (Hand)
0.550 0.450 0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)
0.550 0.450 0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)
0.550 0.450 0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)
0.550 0.450 0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)
0.550 0.450 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.550 0.450 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.548 0.452 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.548 0.452 0.000
M14.4 Arthropathy in amyloidosis
0.548 0.452 0.000
M14.3 Lipoid dermatoarthritis
0.548 0.452 0.000
M14.2 Diabetic arthropathy
0.548 0.452 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.548 0.452 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.548 0.452 0.000
M23.9 Internal derangement of knee, unspecified
0.548 0.452 0.000
M89.8 Other specified disorders of bone
0.546 0.454 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.545 0.455 0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.544 0.456 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.543 0.457 0.000
M07.6 Other enteropathic arthropathies
0.541 0.459 0.000
M07.5 Arthropathy in ulcerative colitis
0.541 0.459 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.541 0.459 0.000
M07.2 Psoriatic spondylitis
0.541 0.459 0.000
M07.1 Arthritis mutilans
0.541 0.459 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.541 0.459 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.541 0.459 0.000
M86.6 Other chronic osteomyelitis
0.539 0.461 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.539 0.461 0.000
M77.1 Lateral epicondylitis
0.537 0.463 0.000
M92.7 Juvenile osteochondrosis of metatarsus
0.537 0.463 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.537 0.463 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.536 0.464 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.535 0.465 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.533 0.467 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.532 0.468 0.000
M25.71 Osteophyte (Shoulder region)
0.532 0.468 0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)
0.528 0.472 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.527 0.472 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.527 0.473 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.526 0.474 0.000
M89.5 Osteolysis
0.525 0.474 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.525 0.474 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.525 0.475 0.000
M06.38 Rheumatoid nodule (Other)
0.525 0.475 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.525 0.475 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.525 0.475 0.000
M06.33 Rheumatoid nodule (Forearm)
0.525 0.475 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.525 0.475 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.525 0.475 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.525 0.475 0.000
M86.8 Other osteomyelitis
0.523 0.477 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.523 0.477 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.523 0.477 0.000
M86.3 Chronic multifocal osteomyelitis
0.523 0.477 0.000
M86.2 Subacute osteomyelitis
0.523 0.477 0.000
M86.1 Other acute osteomyelitis
0.523 0.477 0.000
M86.0 Acute haematogenous osteomyelitis
0.523 0.477 0.000
M84.9 Disorder of continuity of bone, unspecified
0.520 0.479 0.000
M84.8 Other disorders of continuity of bone
0.520 0.479 0.000
M84.3 Stress fracture, not elsewhere classified
0.520 0.479 0.000
M84.2 Delayed union of fracture
0.520 0.479 0.000
M89.3 Hypertrophy of bone
0.520 0.480 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.520 0.480 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.519 0.480 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.518 0.482 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.516 0.484 0.000
M00.94 Pyogenic arthritis, unspecified (Hand)
0.514 0.486 0.000
M25.72 Osteophyte (Upper arm)
0.513 0.487 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.513 0.487 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.512 0.488 0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)
0.510 0.489 0.000
M70.6 Trochanteric bursitis
0.510 0.490 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.510 0.490 0.000
M06.18 Adult-onset Still's disease (Other)
0.510 0.490 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.510 0.490 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.510 0.490 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.510 0.490 0.000
M06.14 Adult-onset Still's disease (Hand)
0.510 0.490 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.510 0.490 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.510 0.490 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.510 0.490 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.510 0.490 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.510 0.490 0.000
M06.28 Rheumatoid bursitis (Other)
0.510 0.490 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.510 0.490 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.510 0.490 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.510 0.490 0.000
M06.24 Rheumatoid bursitis (Hand)
0.510 0.490 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.510 0.490 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.510 0.490 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.510 0.490 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.510 0.490 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.510 0.490 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.510 0.490 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.510 0.490 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.510 0.490 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.510 0.490 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.510 0.490 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.510 0.490 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.510 0.490 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.510 0.490 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.510 0.490 0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec
0.509 0.491 0.000
M21.48 Flat foot [pes planus] (acquired)-Other
0.509 0.491 0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg
0.509 0.491 0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh
0.509 0.491 0.000
M21.44 Flat foot [pes planus] (acquired)-Hand
0.509 0.491 0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm
0.509 0.491 0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm
0.509 0.491 0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region
0.509 0.491 0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites
0.509 0.491 0.000
M08.9 Juvenile arthritis, unspecified
0.507 0.492 0.000
M08.8 Other juvenile arthritis
0.507 0.492 0.000
M08.4 Pauciarticular juvenile arthritis
0.507 0.492 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.507 0.492 0.000
M08.2 Juvenile arthritis with systemic onset
0.507 0.492 0.000
M08.1 Juvenile ankylosing spondylitis
0.507 0.492 0.000
M08.0 Juvenile rheumatoid arthritis
0.507 0.492 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.507 0.492 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.507 0.492 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.507 0.492 0.000
M09.0 Juvenile arthritis in psoriasis
0.507 0.492 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.507 0.492 0.000
M12.5 Traumatic arthropathy
0.507 0.492 0.000
M12.4 Intermittent hydrarthrosis
0.507 0.492 0.000
M12.3 Palindromic rheumatism
0.507 0.492 0.000
M12.2 Villonodular synovitis (pigmented)
0.507 0.492 0.000
M12.1 Kaschin-Beck disease
0.507 0.492 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.507 0.492 0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)
0.507 0.493 0.000
M00.98 Pyogenic arthritis, unspecified (Other)
0.507 0.493 0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)
0.507 0.493 0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)
0.507 0.493 0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)
0.507 0.493 0.000
M67 Other disorders of synovium and tendon
0.507 0.493 0.000
M84.0 Malunion of fracture
0.507 0.493 0.000
M85.65 Other cyst of bone (Pelvic region and thigh)
0.507 0.493 0.000
M25.19 Fistula of joint (Site unspecified)
0.506 0.494 0.000
M25.18 Fistula of joint (Other)
0.506 0.494 0.000
M25.17 Fistula of joint (Ankle and foot)
0.506 0.494 0.000
M25.16 Fistula of joint (Lower leg)
0.506 0.494 0.000
M25.15 Fistula of joint (Pelvic region and thigh)
0.506 0.494 0.000
M25.14 Fistula of joint (Hand)
0.506 0.494 0.000
M25.13 Fistula of joint (Forearm)
0.506 0.494 0.000
M25.12 Fistula of joint (Upper arm)
0.506 0.494 0.000
M25.11 Fistula of joint (Shoulder region)
0.506 0.494 0.000
M25.10 Fistula of joint (Multiple sites)
0.506 0.494 0.000
M25.29 Flail joint (Site unspecified)
0.506 0.494 0.000
M25.28 Flail joint (Other)
0.506 0.494 0.000
M25.27 Flail joint (Ankle and foot)
0.506 0.494 0.000
M25.26 Flail joint (Lower leg)
0.506 0.494 0.000
M25.25 Flail joint (Pelvic region and thigh)
0.506 0.494 0.000
M25.24 Flail joint (Hand)
0.506 0.494 0.000
M25.23 Flail joint (Forearm)
0.506 0.494 0.000
M25.22 Flail joint (Upper arm)
0.506 0.494 0.000
M25.21 Flail joint (Shoulder region)
0.506 0.494 0.000
M25.20 Flail joint (Multiple sites)
0.506 0.494 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.506 0.494 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.506 0.494 0.000
M30.2 Juvenile polyarteritis
0.506 0.494 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.506 0.494 0.000
M30.0 Polyarteritis nodosa
0.506 0.494 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.506 0.494 0.000
M32.8 Other forms of systemic lupus erythematosus
0.506 0.494 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.506 0.494 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.506 0.494 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.506 0.494 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.506 0.494 0.000
M36.3 Arthropathy in other blood disorders
0.506 0.494 0.000
M36.2 Haemophilic arthropathy
0.506 0.494 0.000
M36.1 Arthropathy in neoplastic disease
0.506 0.494 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.506 0.494 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.505 0.494 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.505 0.495 0.000
M62.9 Disorder of muscle, unspecified
0.505 0.495 0.000
M62.6 Muscle strain
0.505 0.495 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.505 0.495 0.000
M62.4 Contracture of muscle
0.505 0.495 0.000
M62.3 Immobility syndrome (paraplegic)
0.505 0.495 0.000
M62.2 Ischaemic infarction of muscle
0.505 0.495 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.505 0.495 0.000
M62.0 Diastasis of muscle
0.505 0.495 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.504 0.495 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.504 0.496 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.504 0.496 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.504 0.496 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.503 0.496 0.000
M93.9 Osteochondropathy, unspecified
0.503 0.497 0.000
M77.5 Other enthesopathy of foot
0.502 0.498 0.000
M66 Spontaneous rupture of synovium and tendon
0.501 0.499 0.000
M89.99 Disorder of bone, unspecified (Site unspecified)
0.500 0.500 0.000
M89.98 Disorder of bone, unspecified (Other)
0.500 0.500 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.500 0.500 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.500 0.500 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.500 0.500 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.500 0.500 0.000
M89.90 Disorder of bone, unspecified (Multiple sites)
0.500 0.500 0.000
M62.88 Other specified disorders of muscle (Other)
0.500 0.500 0.000
M85.98 Disorder of bone density and structure, unspecified (Other)
0.500 0.500 0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)
0.500 0.500 0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)
0.500 0.500 0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)
0.500 0.500 0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)
0.500 0.500 0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)
0.500 0.500 0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)
0.500 0.500 0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)
0.500 0.500 0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)
0.500 0.500 0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.499 0.501 0.000
M65 Synovitis and tenosynovitis
0.498 0.502 0.000
M62.89 Other specified disorders of muscle (Site unspecified)
0.496 0.504 0.000
M60.0 Infective myositis
0.495 0.505 0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)
0.494 0.506 0.000
M23.07 Cystic meniscus-Capsular lig
0.494 0.506 0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)
0.494 0.506 0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.494 0.506 0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)
0.494 0.506 0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.494 0.506 0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.494 0.506 0.000
M23.00 Cystic meniscus (Multiple sites)
0.494 0.506 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.494 0.506 0.000
M99 Biomechanical lesions, not elsewhere classified
0.494 0.506 0.000
M24.56 Contracture of joint (Lower leg)
0.493 0.507 0.000
M92.5 Juvenile osteochondrosis of tibia and fibula
0.492 0.508 0.000
M92.1 Juvenile osteochondrosis of radius and ulna
0.492 0.508 0.000
M92.9 Juvenile osteochondrosis, unspecified
0.492 0.508 0.000
M92.8 Other specified juvenile osteochondrosis
0.492 0.508 0.000
M92.4 Juvenile osteochondrosis of patella
0.492 0.508 0.000
M92.3 Other juvenile osteochondrosis of upper limb
0.492 0.508 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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