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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1632854
log Bayes Factor = 135.241
Chromosome 6   position 30,975,649  (GRCh37) Explore rs1632854 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10.3 With ophthalmic complications
0.994 0.006 0.000
E50-E64 Other nutritional deficiencies
0.986 0.014 0.000
E10.1 With ketoacidosis
0.977 0.023 0.000
E10.4 With neurological complications
0.965 0.035 0.000
E10.2 With renal complications
0.946 0.054 0.000
E14 Unspecified diabetes mellitus
0.946 0.054 0.000
E07 Other disorders of thyroid
0.942 0.058 0.000
E61 Deficiency of other nutrient elements
0.928 0.072 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.919 0.081 0.000
E55 Vitamin D deficiency
0.918 0.082 0.000
E14.3 With ophthalmic complications
0.911 0.089 0.000
E07.9 Disorder of thyroid, unspecified
0.910 0.090 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.900 0.100 0.000
E55.9 Vitamin D deficiency, unspecified
0.869 0.131 0.000
E16 Other disorders of pancreatic internal secretion
0.861 0.139 0.000
L40 Psoriasis
0.000 0.141 0.859
E06 Thyroiditis
0.845 0.155 0.000
E05.8 Other thyrotoxicosis
0.830 0.170 0.000
E61.1 Iron deficiency
0.829 0.171 0.000
E10.7 With multiple complications
0.819 0.181 0.000
L40.0 Psoriasis vulgaris
0.000 0.181 0.819
E61.2 Magnesium deficiency
0.818 0.182 0.000
E14.8 With unspecified complications
0.814 0.186 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.810 0.190 0.000
E14.2 Withrenal complications
0.805 0.195 0.000
E03.8 Other specified hypothyroidism
0.800 0.200 0.000
E51 Thiamine deficiency
0.794 0.206 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.790 0.210 0.000
M45 Ankylosing spondylitis
0.788 0.212 0.000
E10.8 With unspecified complications
0.780 0.220 0.000
K90 Intestinal malabsorption
0.770 0.230 0.000
E16.2 Hypoglycaemia, unspecified
0.769 0.231 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.766 0.234 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.763 0.237 0.000
E06.3 Autoimmune thyroiditis
0.754 0.246 0.000
E53 Deficiency of other B group vitamins
0.732 0.268 0.000
E54 Ascorbic acid deficiency
0.728 0.271 0.000
E14.1 With ketoacidosis
0.725 0.275 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.721 0.279 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E58 Dietary calcium deficiency
0.714 0.286 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.708 0.292 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.707 0.293 0.000
E63 Other nutritional deficiencies
0.707 0.293 0.000
E50 Vitamin A deficiency
0.707 0.293 0.000
E60 Dietary zinc deficiency
0.707 0.293 0.000
E59 Dietary selenium deficiency
0.707 0.293 0.000
E52 Niacin deficiency [pellagra]
0.707 0.293 0.000
E10.0 With coma
0.690 0.310 0.000
E14.7 With multiple complications
0.678 0.322 0.000
E14.0 With coma
0.678 0.322 0.000
E07.1 Dyshormogenetic goitre
0.676 0.324 0.000
E07.0 Hypersecretion of calcitonin
0.676 0.324 0.000
E61.9 Deficiency of nutrient element, unspecified
0.665 0.334 0.000
E61.8 Deficiency of other specified nutrient elements
0.665 0.334 0.000
E61.7 Deficiency of multiple nutrient elements
0.665 0.334 0.000
E61.6 Vanadium deficiency
0.665 0.334 0.000
E61.5 Molybdenum deficiency
0.665 0.334 0.000
E61.4 Chromium deficiency
0.665 0.334 0.000
E61.3 Manganese deficiency
0.665 0.334 0.000
E61.0 Copper deficiency
0.665 0.334 0.000
E14.5 With peripheral circulatory complications
0.665 0.334 0.000
E13 Other specified diabetes mellitus
0.665 0.335 0.000
E03.1 Congenital hypothyroidism without goitre
0.661 0.339 0.000
E15 Nondiabetic hypoglycaemic coma
0.659 0.341 0.000
E55.0 Rickets, active
0.658 0.342 0.000
E51.2 Wernicke's encephalopathy
0.657 0.343 0.000
E10.6 With other specified complications
0.654 0.346 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.651 0.349 0.000
E56 Other vitamin deficiencies
0.650 0.350 0.000
L40.1 Generalised pustular psoriasis
0.000 0.360 0.640
L40.3 Pustulosis palmaris et plantaris
0.000 0.367 0.633
L40.5 Arthropathic psoriasis
0.000 0.367 0.633
E06.5 Other chronic thyroiditis
0.632 0.368 0.000
E14.4 With neurological complications
0.631 0.369 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.617 0.382 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.617 0.382 0.000
E16.4 Abnormal secretion of gastrin
0.617 0.382 0.000
E16.3 Increased secretion of glucagon
0.617 0.382 0.000
L40.4 Guttate psoriasis
0.000 0.384 0.616
L40.2 Acrodermatitis continua
0.000 0.384 0.616
M45.X6 Ankylosing spondylitis (Lumbar region)
0.612 0.388 0.000
E07.8 Other specified disorders of thyroid
0.610 0.390 0.000
E06.4 Drug-induced thyroiditis
0.606 0.394 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.606 0.394 0.000
E06.0 Acute thyroiditis
0.606 0.394 0.000
E53.9 Vitamin B deficiency, unspecified
0.594 0.406 0.000
E16.1 Other hypoglycaemia
0.589 0.411 0.000
L40.8 Other psoriasis
0.000 0.411 0.589
E14.6 With other specified complications
0.582 0.418 0.000
K90.8 Other intestinal malabsorption
0.579 0.421 0.000
E06.1 Subacute thyroiditis
0.577 0.423 0.000
E51.9 Thiamine deficiency, unspecified
0.570 0.430 0.000
E51.8 Other manifestations of thiamine deficiency
0.570 0.430 0.000
E51.1 Beriberi
0.570 0.430 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.565 0.435 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.565 0.435 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.565 0.435 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.565 0.435 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.565 0.435 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.565 0.435 0.000
K90.9 Intestinal malabsorption, unspecified
0.562 0.438 0.000
E06.9 Thyroiditis, unspecified
0.553 0.446 0.000
K90.3 Pancreatic steatorrhoea
0.552 0.448 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.552 0.448 0.000
K90.1 Tropical sprue
0.552 0.448 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.537 0.463 0.000
E53.1 Pyridoxine deficiency
0.525 0.475 0.000
E53.0 Riboflavin deficiency
0.525 0.475 0.000
E13.3 With ophthalmic complications
0.515 0.485 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E50.9 Vitamin A deficiency, unspecified
0.507 0.493 0.000
E50.8 Other manifestations of vitamin A deficiency
0.507 0.493 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.507 0.493 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.507 0.493 0.000
E50.5 Vitamin A deficiency with night blindness
0.507 0.493 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.507 0.493 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.507 0.493 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.507 0.493 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.507 0.493 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.507 0.493 0.000
E63.9 Nutritional deficiency, unspecified
0.507 0.493 0.000
E63.8 Other specified nutritional deficiencies
0.507 0.493 0.000
E63.1 Imbalance of constituents of food intake
0.507 0.493 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.507 0.493 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.507 0.493 0.000
E64.8 Sequelae of other nutritional deficiencies
0.507 0.493 0.000
E64.3 Sequelae of rickets
0.507 0.493 0.000
E64.2 Sequelae of vitamin C deficiency
0.507 0.493 0.000
E64.1 Sequelae of vitamin A deficiency
0.507 0.493 0.000
E64.0 Sequelae of protein-energy malnutrition
0.507 0.493 0.000
E40-E46 Malnutrition
0.501 0.499 0.000
E13.8 With unspecified complications
0.477 0.523 0.000
E13.7 With multiple complications
0.477 0.523 0.000
E13.6 With other specified complications
0.477 0.523 0.000
E13.5 With peripheral circulatory complications
0.477 0.523 0.000
E13.4 With neurological complications
0.477 0.523 0.000
E13.2 With renal complications
0.477 0.523 0.000
E13.1 With ketoacidosis
0.477 0.523 0.000
E13.0 With coma
0.477 0.523 0.000
E10.5 With peripheral circulatory complications
0.477 0.523 0.000
E56.9 Vitamin deficiency, unspecified
0.466 0.534 0.000
E56.8 Deficiency of other vitamins
0.466 0.534 0.000
E56.0 Deficiency of vitamin E
0.466 0.534 0.000
E53.8 Deficiency of other specified B group vitamins
0.459 0.541 0.000
E56.1 Deficiency of vitamin K
0.409 0.591 0.000
E13.9 Without complications
0.366 0.634 0.000
E65-E68 Obesity and other hyperalimentation
0.360 0.640 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.359 0.640 0.000
E45 Retarded development following protein-energy malnutrition
0.359 0.640 0.000
E43 Unspecified severe protein-energy malnutrition
0.359 0.640 0.000
E42 Marasmic kwashiorkor
0.359 0.640 0.000
E41 Nutritional marasmus
0.359 0.640 0.000
E40 Kwashiorkor
0.359 0.640 0.000
E67 Other hyperalimentation
0.258 0.742 0.000
E68 Sequelae of hyperalimentation
0.258 0.742 0.000
E44.1 Mild protein-energy malnutrition
0.257 0.742 0.000
E44.0 Moderate protein-energy malnutrition
0.257 0.742 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.208 0.792 0.000
E65 Localised adiposity
0.206 0.794 0.000
E67.8 Other specified hyperalimentation
0.185 0.815 0.000
E67.3 Hypervitaminosis D
0.185 0.815 0.000
E67.2 Megavitamin-B6 syndrome
0.185 0.815 0.000
E67.1 Hypercarotenaemia
0.185 0.815 0.000
E67.0 Hypervitaminosis A
0.185 0.815 0.000
L40-L45 Papulosquamous disorders
0.001 0.843 0.156
E46 Unspecified protein-energy malnutrition
0.143 0.856 0.001
E14.9 Without complications
0.129 0.871 0.000
M45-M49 Spondylopathies
0.116 0.884 0.000
L44 Other papulosquamous disorders
0.001 0.887 0.112
L41 Parapsoriasis
0.001 0.887 0.112
L45 Papulosquamous disorders in diseases classified elsewhere
0.001 0.887 0.112
L42 Pityriasis rosea
0.001 0.901 0.099
M49 Spondylopathies in diseases classified elsewhere
0.091 0.909 0.000
E20-E35 Disorders of other endocrine glands
0.090 0.910 0.000
L41.9 Parapsoriasis, unspecified
0.001 0.919 0.081
L41.8 Other parapsoriasis
0.001 0.919 0.081
L41.5 Retiform parapsoriasis
0.001 0.919 0.081
L41.4 Large plaque parapsoriasis
0.001 0.919 0.081
L41.3 Small plaque parapsoriasis
0.001 0.919 0.081
L41.2 Lymphomatoid papulosis
0.001 0.919 0.081
L41.1 Pityriasis lichenoides chronica
0.001 0.919 0.081
L41.0 Pityriasis lichenoides et varioliformis acuta
0.001 0.919 0.081
L44.9 Papulosquamous disorder, unspecified
0.001 0.919 0.081
L44.8 Other specified papulosquamous disorders
0.001 0.919 0.081
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.001 0.919 0.081
L44.3 Lichen ruber moniliformis
0.001 0.919 0.081
L44.2 Lichen striatus
0.001 0.919 0.081
L44.1 Lichen nitidus
0.001 0.919 0.081
L44.0 Pityriasis rubra pilaris
0.001 0.919 0.081
K74.3 Primary biliary cirrhosis
0.081 0.919 0.000
M48 Other spondylopathies
0.075 0.925 0.000
E34 Other endocrine disorders
0.075 0.925 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.074 0.926 0.000
M46 Other inflammatory spondylopathies
0.072 0.927 0.000
K74 Fibrosis and cirrhosis of liver
0.072 0.928 0.000
E04 Other non-toxic goitre
0.071 0.929 0.001
E25 Adrenogenital disorders
0.069 0.931 0.000
M48.8 Other specified spondylopathies
0.069 0.931 0.000
K74.6 Other and unspecified cirrhosis of liver
0.069 0.931 0.000
K90-K93 Other diseases of the digestive system
0.069 0.931 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.066 0.934 0.000
M49.4 Neuropathic spondylopathy
0.066 0.934 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.066 0.934 0.000
M49.2 Enterobacterial spondylitis
0.066 0.934 0.000
M49.1 Brucella spondylitis
0.066 0.934 0.000
M49.0 Tuberculosis of spine
0.066 0.934 0.000
E24 Cushing's syndrome
0.066 0.934 0.000
K74.5 Biliary cirrhosis, unspecified
0.065 0.935 0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.065 0.935 0.000
M46.4 Discitis, unspecified
0.065 0.935 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.065 0.935 0.000
E32 Diseases of thymus
0.065 0.935 0.000
E30 Disorders of puberty, not elsewhere classified
0.065 0.935 0.000
E31 Polyglandular dysfunction
0.064 0.935 0.000
E26 Hyperaldosteronism
0.062 0.938 0.000
E20 Hypoparathyroidism
0.062 0.938 0.000
M48.87 Other specified spondylopathies (Lumbosacral region)
0.061 0.939 0.000
M48.9 Spondylopathy, unspecified
0.060 0.940 0.000
E34.3 Short stature, not elsewhere classified
0.059 0.941 0.000
E34.0 Carcinoid syndrome
0.057 0.943 0.000
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)
0.056 0.944 0.000
E34.8 Other specified endocrine disorders
0.056 0.944 0.000
E34.9 Endocrine disorder, unspecified
0.055 0.944 0.000
E66 Obesity
0.055 0.945 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.054 0.946 0.000
M48.4 Fatigue fracture of vertebra
0.054 0.946 0.000
M48.3 Traumatic spondylopathy
0.054 0.946 0.000
M48.2 Kissing spine
0.054 0.946 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.054 0.946 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.054 0.946 0.000
M48.86 Other specified spondylopathies (Lumbar region)
0.054 0.946 0.000
E34.5 Androgen resistance syndrome
0.054 0.946 0.000
E34.4 Constitutional tall stature
0.054 0.946 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.054 0.946 0.000
E34.1 Other hypersecretion of intestinal hormones
0.054 0.946 0.000
E11 Non-insulin-dependent diabetes mellitus
0.053 0.947 0.000
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)
0.053 0.947 0.000
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)
0.053 0.947 0.000
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)
0.053 0.947 0.000
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)
0.053 0.947 0.000
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)
0.053 0.947 0.000
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)
0.053 0.947 0.000
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)
0.053 0.947 0.000
M48.82 Other specified spondylopathies (Cervical region)
0.053 0.947 0.000
E29 Testicular dysfunction
0.052 0.947 0.000
E24.2 Drug-induced Cushing's syndrome
0.052 0.947 0.000
M46.8 Other specified inflammatory spondylopathies
0.052 0.948 0.000
M46.5 Other infective spondylopathies
0.052 0.948 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.052 0.948 0.000
K74.4 Secondary biliary cirrhosis
0.052 0.948 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.052 0.948 0.000
K74.1 Hepatic sclerosis
0.052 0.948 0.000
M46.42 Discitis, unspecified (Cervical region)
0.052 0.948 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.052 0.948 0.000
E04.8 Other specified non-toxic goitre
0.051 0.949 0.001
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)
0.051 0.949 0.000
M48.99 Spondylopathy, unspecified (Site unspecified)
0.051 0.949 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.050 0.950 0.000
M46.2 Osteomyelitis of vertebra
0.050 0.950 0.000
E25.9 Adrenogenital disorder, unspecified
0.050 0.950 0.000
E25.8 Other adrenogenital disorders
0.050 0.950 0.000
M48.89 Other specified spondylopathies (Site unspecified)
0.049 0.950 0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)
0.049 0.950 0.000
M48.84 Other specified spondylopathies (Thoracic region)
0.049 0.950 0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)
0.049 0.950 0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)
0.049 0.950 0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)
0.049 0.950 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.049 0.951 0.000
E24.0 Pituitary-dependent Cushing's disease
0.049 0.951 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.048 0.952 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.048 0.952 0.000
M49.09 Tuberculosis of spine (Site unspecified)
0.047 0.953 0.000
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.047 0.953 0.000
M49.07 Tuberculosis of spine (Lumbosacral region)
0.047 0.953 0.000
M49.06 Tuberculosis of spine (Lumbar region)
0.047 0.953 0.000
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.047 0.953 0.000
M49.04 Tuberculosis of spine (Thoracic region)
0.047 0.953 0.000
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.047 0.953 0.000
M49.02 Tuberculosis of spine (Cervical region)
0.047 0.953 0.000
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)
0.047 0.953 0.000
M49.00 Tuberculosis of spine (Multiple sites in spine)
0.047 0.953 0.000
M49.19 Brucella spondylitis (Site unspecified)
0.047 0.953 0.000
M49.18 Brucella spondylitis (Sacral and sacrococcygeal region)
0.047 0.953 0.000
M49.17 Brucella spondylitis (Lumbosacral region)
0.047 0.953 0.000
M49.16 Brucella spondylitis (Lumbar region)
0.047 0.953 0.000
M49.15 Brucella spondylitis (Thoracolumbar region)
0.047 0.953 0.000
M49.14 Brucella spondylitis (Thoracic region)
0.047 0.953 0.000
M49.13 Brucella spondylitis (Cervicothoracic region)
0.047 0.953 0.000
M49.12 Brucella spondylitis (Cervical region)
0.047 0.953 0.000
M49.11 Brucella spondylitis (Occipito-atlanto-axial region)
0.047 0.953 0.000
M49.10 Brucella spondylitis (Multiple sites in spine)
0.047 0.953 0.000
M49.29 Enterobacterial spondylitis (Site unspecified)
0.047 0.953 0.000
M49.28 Enterobacterial spondylitis (Sacral and sacrococcygeal region)
0.047 0.953 0.000
M49.27 Enterobacterial spondylitis (Lumbosacral region)
0.047 0.953 0.000
M49.26 Enterobacterial spondylitis (Lumbar region)
0.047 0.953 0.000
M49.25 Enterobacterial spondylitis (Thoracolumbar region)
0.047 0.953 0.000
M49.24 Enterobacterial spondylitis (Thoracic region)
0.047 0.953 0.000
M49.23 Enterobacterial spondylitis (Cervicothoracic region)
0.047 0.953 0.000
M49.22 Enterobacterial spondylitis (Cervical region)
0.047 0.953 0.000
M49.21 Enterobacterial spondylitis (Occipito-atlanto-axial region)
0.047 0.953 0.000
M49.20 Enterobacterial spondylitis (Multiple sites in spine)
0.047 0.953 0.000
M49.39 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Site unspecified)
0.047 0.953 0.000
M49.38 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Sacral and sacrococcygeal region)
0.047 0.953 0.000
M49.37 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbosacral region)
0.047 0.953 0.000
M49.36 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbar region)
0.047 0.953 0.000
M49.35 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracolumbar region)
0.047 0.953 0.000
M49.34 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracic region)
0.047 0.953 0.000
M49.33 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervicothoracic region)
0.047 0.953 0.000
M49.32 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervical region)
0.047 0.953 0.000
M49.31 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Occipito-atlanto-axial region)
0.047 0.953 0.000
M49.30 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Multiple sites in spine)
0.047 0.953 0.000
M49.49 Neuropathic spondylopathy (Site unspecified)
0.047 0.953 0.000
M49.48 Neuropathic spondylopathy (Sacral and sacrococcygeal region)
0.047 0.953 0.000
M49.47 Neuropathic spondylopathy (Lumbosacral region)
0.047 0.953 0.000
M49.46 Neuropathic spondylopathy (Lumbar region)
0.047 0.953 0.000
M49.45 Neuropathic spondylopathy (Thoracolumbar region)
0.047 0.953 0.000
M49.44 Neuropathic spondylopathy (Thoracic region)
0.047 0.953 0.000
M49.43 Neuropathic spondylopathy (Cervicothoracic region)
0.047 0.953 0.000
M49.42 Neuropathic spondylopathy (Cervical region)
0.047 0.953 0.000
M49.41 Neuropathic spondylopathy (Occipito-atlanto-axial region)
0.047 0.953 0.000
M49.40 Neuropathic spondylopathy (Multiple sites in spine)
0.047 0.953 0.000
M49.89 Spondylopathy in other diseases classified elsewhere (Site unspecified)
0.047 0.953 0.000
M49.88 Spondylopathy in other diseases classified elsewhere (Sacral and sacrococcygeal region)
0.047 0.953 0.000
M49.87 Spondylopathy in other diseases classified elsewhere (Lumbosacral region)
0.047 0.953 0.000
M49.86 Spondylopathy in other diseases classified elsewhere (Lumbar region)
0.047 0.953 0.000
M49.85 Spondylopathy in other diseases classified elsewhere (Thoracolumbar region)
0.047 0.953 0.000
M49.84 Spondylopathy in other diseases classified elsewhere (Thoracic region)
0.047 0.953 0.000
M49.83 Spondylopathy in other diseases classified elsewhere (Cervicothoracic region)
0.047 0.953 0.000
M49.82 Spondylopathy in other diseases classified elsewhere (Cervical region)
0.047 0.953 0.000
M49.81 Spondylopathy in other diseases classified elsewhere (Occipito-atlanto-axial region)
0.047 0.953 0.000
M49.80 Spondylopathy in other diseases classified elsewhere (Multiple sites in spine)
0.047 0.953 0.000
E24.8 Other Cushing's syndrome
0.047 0.953 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.047 0.953 0.000
E24.3 Ectopic ACTH syndrome
0.047 0.953 0.000
E24.1 Nelson's syndrome
0.047 0.953 0.000
E04.0 Non-toxic diffuse goitre
0.047 0.953 0.001
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.047 0.953 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.047 0.953 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.047 0.953 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.047 0.953 0.000
E30.9 Disorder of puberty, unspecified
0.047 0.953 0.000
E30.8 Other disorders of puberty
0.047 0.953 0.000
E30.1 Precocious puberty
0.047 0.953 0.000
E30.0 Delayed puberty
0.047 0.953 0.000
E32.9 Disease of thymus, unspecified
0.047 0.953 0.000
E32.8 Other diseases of thymus
0.047 0.953 0.000
E32.1 Abscess of thymus
0.047 0.953 0.000
E32.0 Persistent hyperplasia of thymus
0.047 0.953 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.047 0.953 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.047 0.953 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.047 0.953 0.000
E31.9 Polyglandular dysfunction, unspecified
0.046 0.953 0.000
E31.8 Other polyglandular dysfunction
0.046 0.953 0.000
E31.1 Polyglandular hyperfunction
0.046 0.953 0.000
E31.0 Autoimmune polyglandular failure
0.046 0.954 0.000
M46.0 Spinal enthesopathy
0.046 0.954 0.000
E28 Ovarian dysfunction
0.045 0.955 0.000
E26.8 Other hyperaldosteronism
0.045 0.955 0.000
E26.1 Secondary hyperaldosteronism
0.045 0.955 0.000
E20.8 Other hypoparathyroidism
0.045 0.955 0.000
E20.1 Pseudohypoparathyroidism
0.045 0.955 0.000
E20.0 Idiopathic hypoparathyroidism
0.045 0.955 0.000
M48.92 Spondylopathy, unspecified (Cervical region)
0.044 0.955 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.044 0.956 0.000
M46.40 Discitis, unspecified (Multiple sites in spine)
0.044 0.956 0.000
E26.0 Primary hyperaldosteronism
0.044 0.956 0.000
K72 Hepatic failure, not elsewhere classified
0.044 0.956 0.000
K70-K77 Diseases of liver
0.043 0.957 0.000
E26.9 Hyperaldosteronism, unspecified
0.043 0.957 0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.043 0.957 0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)
0.043 0.957 0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)
0.043 0.957 0.000
M48.94 Spondylopathy, unspecified (Thoracic region)
0.043 0.957 0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)
0.043 0.957 0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)
0.043 0.957 0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)
0.043 0.957 0.000
E22 Hyperfunction of pituitary gland
0.043 0.957 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.042 0.958 0.000
E11.7 With multiple complications
0.042 0.958 0.000
K72.9 Hepatic failure, unspecified
0.042 0.958 0.000
L43 Lichen planus
0.001 0.958 0.041
M46.19 Sacroiliitis, not elsewhere classified-Site unspe
0.042 0.958 0.000
E20.9 Hypoparathyroidism, unspecified
0.042 0.958 0.000
E23 Hypofunction and other disorders of pituitary gland
0.041 0.958 0.000
E11.0 With coma
0.041 0.959 0.000
E11.1 With ketoacidosis
0.041 0.959 0.000
E66.1 Drug-induced obesity
0.040 0.960 0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)
0.039 0.960 0.000
E21.4 Other specified disorders of parathyroid gland
0.039 0.961 0.000
E24.9 Cushing's syndrome, unspecified
0.039 0.961 0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral
0.039 0.961 0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar
0.039 0.961 0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar
0.039 0.961 0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic
0.039 0.961 0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic
0.039 0.961 0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical
0.039 0.961 0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl
0.039 0.961 0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site
0.039 0.961 0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)
0.039 0.961 0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)
0.039 0.961 0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)
0.039 0.961 0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)
0.039 0.961 0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)
0.039 0.961 0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)
0.039 0.961 0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)
0.039 0.961 0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)
0.039 0.961 0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)
0.039 0.961 0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)
0.039 0.961 0.000
M48.29 Kissing spine (Site unspecified)
0.039 0.961 0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)
0.039 0.961 0.000
M48.27 Kissing spine (Lumbosacral region)
0.039 0.961 0.000
M48.26 Kissing spine (Lumbar region)
0.039 0.961 0.000
M48.25 Kissing spine (Thoracolumbar region)
0.039 0.961 0.000
M48.24 Kissing spine (Thoracic region)
0.039 0.961 0.000
M48.23 Kissing spine (Cervicothoracic region)
0.039 0.961 0.000
M48.22 Kissing spine (Cervical region)
0.039 0.961 0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)
0.039 0.961 0.000
M48.20 Kissing spine (Multiple sites in spine)
0.039 0.961 0.000
M48.39 Traumatic spondylopathy (Site unspecified)
0.039 0.961 0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)
0.039 0.961 0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)
0.039 0.961 0.000
M48.36 Traumatic spondylopathy (Lumbar region)
0.039 0.961 0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)
0.039 0.961 0.000
M48.34 Traumatic spondylopathy (Thoracic region)
0.039 0.961 0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)
0.039 0.961 0.000
M48.32 Traumatic spondylopathy (Cervical region)
0.039 0.961 0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)
0.039 0.961 0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)
0.039 0.961 0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)
0.039 0.961 0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)
0.039 0.961 0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)
0.039 0.961 0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)
0.039 0.961 0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)
0.039 0.961 0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)
0.039 0.961 0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)
0.039 0.961 0.000
M48.42 Fatigue fracture of vertebra (Cervical region)
0.039 0.961 0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)
0.039 0.961 0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)
0.039 0.961 0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ
0.038 0.962 0.000
E29.9 Testicular dysfunction, unspecified
0.038 0.962 0.000
E29.8 Other testicular dysfunction
0.038 0.962 0.000
E29.0 Testicular hyperfunction
0.038 0.962 0.000
K72.0 Acute and subacute hepatic failure
0.038 0.962 0.000
M48.96 Spondylopathy, unspecified (Lumbar region)
0.038 0.962 0.000
E11.6 With other specified complications
0.038 0.962 0.000
M46.59 Other infective spondylopathies (Site unspecified)
0.037 0.962 0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)
0.037 0.962 0.000
M46.57 Other infective spondylopathies (Lumbosacral region)
0.037 0.962 0.000
M46.56 Other infective spondylopathies (Lumbar region)
0.037 0.962 0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)
0.037 0.962 0.000
M46.54 Other infective spondylopathies (Thoracic region)
0.037 0.962 0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)
0.037 0.962 0.000
M46.52 Other infective spondylopathies (Cervical region)
0.037 0.962 0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)
0.037 0.962 0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)
0.037 0.962 0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)
0.037 0.962 0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)
0.037 0.962 0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)
0.037 0.962 0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)
0.037 0.962 0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)
0.037 0.962 0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)
0.037 0.962 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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