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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1634714
log Bayes Factor = 80.1762
Chromosome 6   position 30,951,561  (GRCh37) Explore rs1634714 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
D80-D89 Certain disorders involving the immune mechanism
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
D86 Sarcoidosis
0.999 0.001 0.000
E16 Other disorders of pancreatic internal secretion
0.999 0.001 0.000
E16.2 Hypoglycaemia, unspecified
0.999 0.001 0.000
D86.9 Sarcoidosis, unspecified
0.996 0.004 0.000
E14 Unspecified diabetes mellitus
0.995 0.005 0.000
K70-K77 Diseases of liver
0.995 0.005 0.000
K75 Other inflammatory liver diseases
0.994 0.006 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.994 0.006 0.000
Chapter VII Diseases of the eye and adnexa
0.994 0.006 0.000
K75.4 Autoimmune hepatitis
0.993 0.007 0.000
E10.1 With ketoacidosis
0.993 0.007 0.000
Chapter IX Diseases of the circulatory system
0.992 0.008 0.000
H36.0 Diabetic retinopathy
0.992 0.008 0.000
H36 Retinal disorders in diseases classified elsewhere
0.991 0.009 0.000
H30-H36 Disorders of choroid and retina
0.990 0.010 0.000
I74 Arterial embolism and thrombosis
0.989 0.011 0.000
K74 Fibrosis and cirrhosis of liver
0.988 0.012 0.000
I73 Other peripheral vascular diseases
0.987 0.013 0.000
E10.2 With renal complications
0.986 0.014 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.984 0.016 0.000
M15-M19 Arthrosis
0.981 0.019 0.000
I73.9 Peripheral vascular disease, unspecified
0.981 0.019 0.000
E14.3 With ophthalmic complications
0.979 0.021 0.000
D60-D64 Aplastic and other anaemias
0.978 0.022 0.000
E50-E64 Other nutritional deficiencies
0.974 0.026 0.000
K74.6 Other and unspecified cirrhosis of liver
0.962 0.038 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.954 0.046 0.000
K73 Chronic hepatitis, not elsewhere classified
0.952 0.048 0.000
K74.3 Primary biliary cirrhosis
0.950 0.050 0.000
D61 Other aplastic anaemias
0.944 0.056 0.000
M17 Gonarthrosis [arthrosis of knee]
0.942 0.058 0.000
E10.4 With neurological complications
0.942 0.058 0.000
M18 Arthrosis of first carpometacarpal joint
0.941 0.059 0.000
D64 Other anaemias
0.937 0.063 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.936 0.064 0.000
K72 Hepatic failure, not elsewhere classified
0.934 0.066 0.000
D80 Immunodeficiency with predominantly antibody defects
0.933 0.067 0.000
M17.1 Other primary gonarthrosis
0.930 0.070 0.000
Chapter XI Diseases of the digestive system
0.927 0.073 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.925 0.075 0.000
E53 Deficiency of other B group vitamins
0.924 0.076 0.000
E20-E35 Disorders of other endocrine glands
0.923 0.077 0.000
H06.2 Dysthyroid exophthalmos
0.923 0.077 0.000
Chapter I Certain infectious and parasitic diseases
0.919 0.081 0.000
I10-I15 Hypertensive diseases
0.916 0.084 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.913 0.087 0.000
E27.1 Primary adrenocortical insufficiency
0.912 0.088 0.000
E27 Other disorders of adrenal gland
0.911 0.089 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.911 0.089 0.000
K75.8 Other specified inflammatory liver diseases
0.909 0.091 0.000
M15 Polyarthrosis
0.908 0.092 0.000
D69 Purpura and other haemorrhagic conditions
0.907 0.093 0.000
G35 Multiple sclerosis
0.907 0.093 0.000
D61.9 Aplastic anaemia, unspecified
0.906 0.094 0.000
B35-B49 Mycoses
0.906 0.094 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.904 0.096 0.000
Chapter VI Diseases of the nervous system
0.902 0.098 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.902 0.098 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.902 0.098 0.000
D86.0 Sarcoidosis of lung
0.900 0.100 0.000
B37 Candidiasis
0.898 0.102 0.000
I12 Hypertensive renal disease
0.897 0.103 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.896 0.104 0.000
H05 Disorders of orbit
0.895 0.105 0.000
E07 Other disorders of thyroid
0.893 0.107 0.000
D64.9 Anaemia, unspecified
0.893 0.107 0.000
E06 Thyroiditis
0.892 0.108 0.000
E53.8 Deficiency of other specified B group vitamins
0.885 0.115 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.885 0.115 0.000
I12.9 Hypertensive renal disease without renal failure
0.882 0.118 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.879 0.121 0.000
M34 Systemic sclerosis
0.878 0.122 0.000
M60-M63 Disorders of muscles
0.874 0.126 0.000
M21 Other acquired deformities of limbs
0.874 0.126 0.000
E03.8 Other specified hypothyroidism
0.874 0.126 0.000
D55-D59 Haemolytic anaemias
0.863 0.137 0.000
B37.9 Candidiasis, unspecified
0.860 0.140 0.000
B37.8 Candidiasis of other sites
0.858 0.142 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.857 0.143 0.000
H43-H45 Disorders of vitreous body and globe
0.856 0.144 0.000
M35.3 Polymyalgia rheumatica
0.854 0.146 0.000
M24 Other specific joint derangements
0.851 0.149 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.849 0.151 0.000
K90-K93 Other diseases of the digestive system
0.847 0.153 0.000
I74.5 Embolism and thrombosis of iliac artery
0.844 0.156 0.000
K90 Intestinal malabsorption
0.842 0.158 0.000
D86.1 Sarcoidosis of lymph nodes
0.842 0.158 0.000
C85.1 B-cell lymphoma, unspecified
0.842 0.158 0.000
C81 Hodgkin's disease
0.839 0.161 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.838 0.162 0.000
D83 Common variable immunodeficiency
0.838 0.162 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.832 0.168 0.000
M32 Systemic lupus erythematosus
0.831 0.169 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.830 0.170 0.000
K90.9 Intestinal malabsorption, unspecified
0.829 0.171 0.000
E61 Deficiency of other nutrient elements
0.829 0.171 0.000
I73.0 Raynaud's syndrome
0.829 0.171 0.000
K73.9 Chronic hepatitis, unspecified
0.829 0.171 0.000
E14.2 Withrenal complications
0.828 0.172 0.000
E14.1 With ketoacidosis
0.828 0.172 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.825 0.175 0.000
K72.0 Acute and subacute hepatic failure
0.825 0.175 0.000
D69.6 Thrombocytopenia, unspecified
0.825 0.175 0.000
H30 Chorioretinal inflammation
0.823 0.177 0.000
E14.8 With unspecified complications
0.821 0.179 0.000
B37.0 Candidal stomatitis
0.817 0.183 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.816 0.184 0.000
K72.9 Hepatic failure, unspecified
0.814 0.186 0.000
E06.3 Autoimmune thyroiditis
0.812 0.188 0.000
A30-A49 Other bacterial diseases
0.809 0.191 0.000
G56 Mononeuropathies of upper limb
0.808 0.192 0.000
I77 Other disorders of arteries and arterioles
0.807 0.193 0.000
D50-D53 Nutritional anaemias
0.806 0.194 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.806 0.194 0.000
G56.0 Carpal tunnel syndrome
0.804 0.196 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.804 0.196 0.000
M22 Disorders of patella
0.802 0.198 0.000
C88 Malignant immunoproliferative diseases
0.801 0.199 0.000
M35.7 Hypermobility syndrome
0.797 0.202 0.000
I74.8 Embolism and thrombosis of other arteries
0.797 0.203 0.000
B15-B19 Viral hepatitis
0.796 0.204 0.000
E51 Thiamine deficiency
0.790 0.210 0.000
H34 Retinal vascular occlusions
0.789 0.211 0.000
C91 Lymphoid leukaemia
0.786 0.214 0.000
H43 Disorders of vitreous body
0.784 0.216 0.000
H05.2 Exophthalmic conditions
0.784 0.216 0.000
E10.7 With multiple complications
0.783 0.217 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.783 0.217 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.780 0.220 0.000
D69.4 Other primary thrombocytopenia
0.778 0.222 0.000
E11 Non-insulin-dependent diabetes mellitus
0.778 0.222 0.000
D69.5 Secondary thrombocytopenia
0.777 0.222 0.000
E07.9 Disorder of thyroid, unspecified
0.777 0.223 0.000
I11 Hypertensive heart disease
0.776 0.224 0.000
C83.3 Large cell (diffuse)
0.776 0.224 0.000
K74.5 Biliary cirrhosis, unspecified
0.775 0.225 0.000
E14.6 With other specified complications
0.774 0.226 0.000
M17.3 Other posttraumatic gonarthrosis
0.773 0.227 0.000
D59 Acquired haemolytic anaemia
0.772 0.228 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.772 0.228 0.000
G30-G32 Other degenerative diseases of the nervous system
0.772 0.228 0.000
Chapter II Neoplasms
0.767 0.233 0.000
R04.0 Epistaxis
0.000 0.233 0.767
E10.0 With coma
0.767 0.233 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.766 0.234 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.766 0.234 0.000
M24.1 Other articular cartilage disorders
0.766 0.234 0.000
E10.8 With unspecified complications
0.763 0.236 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.763 0.237 0.000
M21.0 Valgus deformity, not elsewhere classified
0.761 0.239 0.000
D86.8 Sarcoidosis of other and combined sites
0.761 0.239 0.000
C83.0 Small cell (diffuse)
0.760 0.240 0.000
M21.8 Other specified acquired deformities of limbs
0.759 0.241 0.000
A41 Other septicaemia
0.757 0.243 0.000
M80-M85 Disorders of bone density and structure
0.757 0.243 0.000
D51 Vitamin B12 deficiency anaemia
0.756 0.244 0.000
D64.8 Other specified anaemias
0.754 0.245 0.000
I72 Other aneurysm
0.754 0.246 0.000
H43.1 Vitreous haemorrhage
0.753 0.247 0.000
M40-M43 Deforming dorsopathies
0.751 0.249 0.000
D82 Immunodeficiency associated with other major defects
0.749 0.251 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.749 0.251 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.749 0.251 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.748 0.252 0.000
M35.1 Other overlap syndromes
0.745 0.255 0.000
H05.8 Other disorders of orbit
0.745 0.255 0.000
I77.1 Stricture of artery
0.742 0.258 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.741 0.259 0.000
M62 Other disorders of muscle
0.740 0.260 0.000
C16 Malignant neoplasm of stomach
0.740 0.260 0.000
J33.0 Polyp of nasal cavity
0.739 0.261 0.000
A41.9 Septicaemia, unspecified
0.738 0.262 0.000
E10.5 With peripheral circulatory complications
0.738 0.262 0.000
C84.5 Other and unspecified T-cell lymphomas
0.737 0.262 0.000
E14.5 With peripheral circulatory complications
0.737 0.263 0.000
C92 Myeloid leukaemia
0.737 0.263 0.000
C15-C26 Malignant neoplasms of digestive organs
0.736 0.264 0.000
G51 Facial nerve disorders
0.736 0.264 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.735 0.265 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.734 0.266 0.000
M34.1 CR(E)ST syndrome
0.734 0.266 0.000
D61.1 Drug-induced aplastic anaemia
0.733 0.267 0.000
C16.9 Stomach, unspecified
0.733 0.267 0.000
M21.6 Other acquired deformities of ankle and foot
0.732 0.268 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.732 0.268 0.000
E24 Cushing's syndrome
0.732 0.268 0.000
M00-M03 Infectious arthropathies
0.731 0.269 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.730 0.270 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.730 0.270 0.000
E07.8 Other specified disorders of thyroid
0.727 0.273 0.000
D69.2 Other nonthrombocytopenic purpura
0.727 0.273 0.000
E20 Hypoparathyroidism
0.726 0.273 0.000
M15.8 Other polyarthrosis
0.725 0.275 0.000
M86-M90 Other osteopathies
0.725 0.275 0.000
M33 Dermatopolymyositis
0.722 0.278 0.000
Q50-Q56 Congenital malformations of genital organs
0.722 0.278 0.000
D83.9 Common variable immunodeficiency, unspecified
0.722 0.278 0.000
D61.0 Constitutional aplastic anaemia
0.721 0.279 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.718 0.282 0.000
E31 Polyglandular dysfunction
0.718 0.282 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
D81 Combined immunodeficiencies
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.716 0.284 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.284 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.284 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.284 0.000
E16.3 Increased secretion of glucagon
0.716 0.284 0.000
E14.7 With multiple complications
0.714 0.286 0.000
E14.0 With coma
0.714 0.286 0.000
C81.9 Hodgkin's disease, unspecified
0.714 0.286 0.000
M15.4 Erosive (osteo)arthrosis
0.714 0.286 0.000
K77 Liver disorders in diseases classified elsewhere
0.713 0.287 0.000
K71 Toxic liver disease
0.713 0.287 0.000
K75.2 Nonspecific reactive hepatitis
0.713 0.287 0.000
K75.1 Phlebitis of portal vein
0.713 0.287 0.000
I00-I02 Acute rheumatic fever
0.711 0.288 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.710 0.290 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.710 0.290 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.710 0.290 0.000
M60 Myositis
0.710 0.290 0.000
I77.6 Arteritis, unspecified
0.709 0.291 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.709 0.291 0.000
K74.4 Secondary biliary cirrhosis
0.709 0.291 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.709 0.291 0.000
K74.1 Hepatic sclerosis
0.709 0.291 0.000
M15.1 Heberden's nodes (with arthropathy)
0.708 0.292 0.000
C81.1 Nodular sclerosis
0.708 0.292 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.708 0.292 0.000
B37.7 Candidal septicaemia
0.706 0.294 0.000
M24.7 Protrusio acetabuli
0.705 0.295 0.000
H30.9 Chorioretinal inflammation, unspecified
0.704 0.296 0.000
J33 Nasal polyp
0.703 0.297 0.000
L50-L54 Urticaria and erythema
0.702 0.298 0.000
I70 Atherosclerosis
0.702 0.298 0.000
H50 Other strabismus
0.702 0.298 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.701 0.298 0.000
K72.1 Chronic hepatic failure
0.701 0.299 0.000
B44 Aspergillosis
0.700 0.300 0.000
L10-L14 Bullous disorders
0.699 0.301 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.699 0.301 0.000
E63 Other nutritional deficiencies
0.699 0.301 0.000
E56 Other vitamin deficiencies
0.699 0.301 0.000
E50 Vitamin A deficiency
0.699 0.301 0.000
E60 Dietary zinc deficiency
0.699 0.301 0.000
E59 Dietary selenium deficiency
0.699 0.301 0.000
E54 Ascorbic acid deficiency
0.699 0.301 0.000
E52 Niacin deficiency [pellagra]
0.699 0.301 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.698 0.302 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.698 0.302 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.698 0.302 0.000
E58 Dietary calcium deficiency
0.697 0.302 0.000
D86.3 Sarcoidosis of skin
0.697 0.303 0.000
E14.9 Without complications
0.697 0.303 0.000
E10.6 With other specified complications
0.696 0.304 0.000
I60-I69 Cerebrovascular diseases
0.695 0.305 0.000
B37.2 Candidiasis of skin and nail
0.695 0.305 0.000
I27 Other pulmonary heart diseases
0.695 0.305 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.695 0.305 0.000
H05.0 Acute inflammation of orbit
0.694 0.306 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.694 0.306 0.000
M34.9 Systemic sclerosis, unspecified
0.691 0.309 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.691 0.309 0.000
C93 Monocytic leukaemia
0.691 0.309 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.691 0.309 0.000
E55 Vitamin D deficiency
0.690 0.309 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.690 0.310 0.000
Chapter X Diseases of the respiratory system
0.690 0.310 0.000
B25-B34 Other viral diseases
0.689 0.311 0.000
I63 Cerebral infarction
0.687 0.313 0.000
A15-A19 Tuberculosis
0.685 0.314 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.685 0.315 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.682 0.317 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.682 0.317 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.682 0.317 0.000
M35.2 Behcet's disease
0.682 0.318 0.000
H05.4 Enophthalmos
0.681 0.319 0.000
M34.0 Progressive systemic sclerosis
0.681 0.319 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.680 0.320 0.000
E53.9 Vitamin B deficiency, unspecified
0.680 0.320 0.000
E13 Other specified diabetes mellitus
0.679 0.320 0.000
E61.1 Iron deficiency
0.679 0.321 0.000
D84 Other immunodeficiencies
0.679 0.321 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.679 0.321 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.679 0.321 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.678 0.322 0.000
L13 Other bullous disorders
0.678 0.322 0.000
D61.8 Other specified aplastic anaemias
0.677 0.323 0.000
D61.3 Idiopathic aplastic anaemia
0.677 0.323 0.000
D61.2 Aplastic anaemia due to other external agents
0.677 0.323 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.676 0.324 0.000
C91.1 Chronic lymphocytic leukaemia
0.676 0.324 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.676 0.324 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.675 0.325 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.675 0.325 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.675 0.325 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.675 0.325 0.000
M24.2 Disorder of ligament
0.675 0.325 0.000
K75.9 Inflammatory liver disease, unspecified
0.675 0.325 0.000
J40-J47 Chronic lower respiratory diseases
0.675 0.325 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.674 0.326 0.000
D64.4 Congenital dyserythropoietic anaemia
0.672 0.328 0.000
D64.3 Other sideroblastic anaemias
0.672 0.328 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.672 0.328 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.672 0.328 0.000
D64.0 Hereditary sideroblastic anaemia
0.672 0.328 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.671 0.329 0.000
H06.3 Other disorders of orbit in diseases classified elsewhere
0.671 0.329 0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.671 0.329 0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.671 0.329 0.000
E05.8 Other thyrotoxicosis
0.669 0.331 0.000
C83.1 Small cleaved cell (diffuse)
0.669 0.331 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.669 0.331 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.669 0.331 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.669 0.331 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.669 0.331 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.669 0.331 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.669 0.331 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.669 0.331 0.000
M25 Other joint disorders, not elsewhere classified
0.669 0.331 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.668 0.332 0.000
D69.9 Haemorrhagic condition, unspecified
0.668 0.332 0.000
C84.4 Peripheral T-cell lymphoma
0.667 0.333 0.000
E16.1 Other hypoglycaemia
0.667 0.333 0.000
M30 Polyarteritis nodosa and related conditions
0.666 0.333 0.000
M80 Osteoporosis with pathological fracture
0.667 0.333 0.000
E61.2 Magnesium deficiency
0.666 0.334 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.666 0.334 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.666 0.334 0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere
0.664 0.336 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.663 0.336 0.000
L13.0 Dermatitis herpetiformis
0.663 0.337 0.000
B18 Chronic viral hepatitis
0.663 0.337 0.000
D67 Hereditary factor IX deficiency
0.663 0.337 0.000
E53.1 Pyridoxine deficiency
0.662 0.337 0.000
E53.0 Riboflavin deficiency
0.662 0.337 0.000
A46 Erysipelas
0.662 0.338 0.000
E40-E46 Malnutrition
0.662 0.338 0.000
M17.0 Primary gonarthrosis, bilateral
0.662 0.338 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.662 0.338 0.000
E32 Diseases of thymus
0.662 0.338 0.000
E30 Disorders of puberty, not elsewhere classified
0.662 0.338 0.000
E25 Adrenogenital disorders
0.662 0.338 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.661 0.339 0.000
J44 Other chronic obstructive pulmonary disease
0.661 0.339 0.000
M21.9 Acquired deformity of limb, unspecified
0.661 0.339 0.000
E11.3 With ophthalmic complications
0.660 0.340 0.000
M15.9 Polyarthrosis, unspecified
0.659 0.341 0.000
H50.2 Vertical strabismus
0.659 0.341 0.000
M22.8 Other disorders of patella
0.659 0.341 0.000
M35.8 Other specified systemic involvement of connective tissue
0.659 0.341 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.659 0.341 0.000
A75-A79 Rickettsioses
0.659 0.341 0.000
A70-A74 Other diseases caused by chlamydiae
0.659 0.341 0.000
A20-A28 Certain zoonotic bacterial diseases
0.659 0.341 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.659 0.341 0.000
E51.2 Wernicke's encephalopathy
0.658 0.342 0.000
C84.0 Mycosis fungoides
0.658 0.342 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.658 0.342 0.000
I13 Hypertensive heart and renal disease
0.657 0.343 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.655 0.345 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.654 0.346 0.000
C94 Other leukaemias of specified cell type
0.654 0.346 0.000
C86 Other specified types of T/NK-cell lymphoma
0.654 0.346 0.000
E14.4 With neurological complications
0.654 0.346 0.000
E27.5 Adrenomedullary hyperfunction
0.653 0.346 0.000
E27.0 Other adrenocortical overactivity
0.653 0.346 0.000
M17.5 Other secondary gonarthrosis
0.653 0.346 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.653 0.347 0.000
C85.0 Lymphosarcoma
0.653 0.347 0.000
M65-M68 Disorders of synovium and tendon
0.653 0.347 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.652 0.348 0.000
B35 Dermatophytosis
0.652 0.348 0.000
H05.9 Disorder of orbit, unspecified
0.652 0.348 0.000
M62.8 Other specified disorders of muscle
0.652 0.348 0.000
C81.2 Mixed cellularity
0.652 0.348 0.000
M15.0 Primary generalised (osteo)arthrosis
0.651 0.349 0.000
M15.3 Secondary multiple arthrosis
0.651 0.349 0.000
D69.8 Other specified haemorrhagic conditions
0.651 0.349 0.000
D69.1 Qualitative platelet defects
0.651 0.349 0.000
A65-A69 Other spirochaetal diseases
0.650 0.350 0.000
B48 Other mycoses, not elsewhere classified
0.650 0.350 0.000
B47 Mycetoma
0.650 0.350 0.000
B46 Zygomycosis
0.650 0.350 0.000
B45 Cryptococcosis
0.650 0.350 0.000
B43 Chromomycosis and phaeomycotic abscess
0.650 0.350 0.000
B42 Sporotrichosis
0.650 0.350 0.000
B41 Paracoccidioidomycosis
0.650 0.350 0.000
B40 Blastomycosis
0.650 0.350 0.000
B39 Histoplasmosis
0.650 0.350 0.000
B38 Coccidioidomycosis
0.650 0.350 0.000
A48 Other bacterial diseases, not elsewhere classified
0.650 0.350 0.000
J30-J39 Other diseases of upper respiratory tract
0.649 0.351 0.000
G50 Disorders of trigeminal nerve
0.649 0.351 0.000
E06.9 Thyroiditis, unspecified
0.649 0.351 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.649 0.351 0.000
G51.9 Disorder of facial nerve, unspecified
0.649 0.351 0.000
I79.1 Aortitis in diseases classified elsewhere
0.648 0.351 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.648 0.351 0.000
H46 Optic neuritis
0.648 0.352 0.000
I12.0 Hypertensive renal disease with renal failure
0.648 0.352 0.000
E11.1 With ketoacidosis
0.648 0.352 0.000
G36 Other acute disseminated demyelination
0.647 0.353 0.000
B36 Other superficial mycoses
0.647 0.353 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.646 0.354 0.000
H34.8 Other retinal vascular occlusions
0.645 0.355 0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)
0.644 0.356 0.000
B37.6 Candidal endocarditis
0.644 0.356 0.000
B37.5 Candidal meningitis
0.644 0.356 0.000
J45 Asthma
0.644 0.356 0.000
D89.1 Cryoglobulinaemia
0.642 0.358 0.000
Q51 Congenital malformations of uterus and cervix
0.642 0.358 0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.642 0.358 0.000
H05.3 Deformity of orbit
0.642 0.358 0.000
H05.1 Chronic inflammatory disorders of orbit
0.642 0.358 0.000
M22.3 Other derangements of patella
0.641 0.359 0.000
E07.1 Dyshormogenetic goitre
0.640 0.359 0.000
E07.0 Hypersecretion of calcitonin
0.640 0.359 0.000
G31.8 Other specified degenerative diseases of nervous system
0.640 0.360 0.000
C16.8 Overlapping lesion of stomach
0.640 0.360 0.000
E06.5 Other chronic thyroiditis
0.640 0.360 0.000
E06.4 Drug-induced thyroiditis
0.640 0.360 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.640 0.360 0.000
E06.1 Subacute thyroiditis
0.640 0.360 0.000
E06.0 Acute thyroiditis
0.640 0.360 0.000
I63.8 Other cerebral infarction
0.639 0.361 0.000
G56.1 Other lesions of median nerve
0.639 0.361 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.637 0.362 0.000
L52 Erythema nodosum
0.637 0.363 0.000
D59.1 Other autoimmune haemolytic anaemias
0.636 0.364 0.000
C92.1 Chronic myeloid leukaemia
0.635 0.365 0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere
0.635 0.365 0.000
C95 Leukaemia of unspecified cell type
0.634 0.365 0.000
J45.9 Asthma, unspecified
0.635 0.365 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.634 0.366 0.000
M21.7 Unequal limb length (acquired)
0.633 0.367 0.000
E22 Hyperfunction of pituitary gland
0.633 0.367 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.632 0.368 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.631 0.369 0.000
K90.8 Other intestinal malabsorption
0.631 0.369 0.000
B25 Cytomegaloviral disease
0.630 0.370 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.629 0.370 0.000
M22.2 Patellofemoral disorders
0.627 0.372 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.627 0.373 0.000
M61 Calcification and ossification of muscle
0.627 0.373 0.000
B16 Acute hepatitis B
0.627 0.373 0.000
E11.7 With multiple complications
0.626 0.374 0.000
M34.8 Other forms of systemic sclerosis
0.626 0.374 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.626 0.374 0.000
E11.5 With peripheral circulatory complications
0.625 0.375 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.623 0.377 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.623 0.377 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.623 0.377 0.000
J33.9 Nasal polyp, unspecified
0.622 0.378 0.000
I73.8 Other specified peripheral vascular diseases
0.621 0.379 0.000
I62 Other nontraumatic intracranial haemorrhage
0.620 0.380 0.000
G54 Nerve root and plexus disorders
0.619 0.381 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.619 0.381 0.000
D57 Sickle-cell disorders
0.618 0.381 0.000
D55 Anaemia due to enzyme disorders
0.618 0.381 0.000
D56 Thalassaemia
0.618 0.382 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.618 0.382 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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