TreeWAS – Variant ID: rs1667255

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.002	0.998
C78.0 Secondary malignant neoplasm of lung	0.000	0.003	0.997
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.025	0.975
C78.2 Secondary malignant neoplasm of pleura	0.000	0.034	0.966
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.057	0.943
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.060	0.940
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.142	0.858
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.176	0.824
C78.7 Secondary malignant neoplasm of liver	0.000	0.266	0.734
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.315	0.685
J33.8 Other polyp of sinus	0.000	0.966	0.034
F41.2 Mixed anxiety and depressive disorder	0.033	0.967	0.000
J33.0 Polyp of nasal cavity	0.000	0.971	0.029
J33 Nasal polyp	0.000	0.974	0.026
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.975	0.025
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.983	0.017
J38.3 Other diseases of vocal cords	0.000	0.983	0.017
J33.1 Polypoid sinus degeneration	0.000	0.984	0.016
C76.3 Pelvis	0.000	0.986	0.014
C76.1 Thorax	0.000	0.987	0.012
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.987	0.012
C76.7 Other ill-defined sites	0.000	0.987	0.012
C76.5 Lower limb	0.000	0.987	0.012
C76.4 Upper limb	0.000	0.987	0.012
C76.2 Abdomen	0.000	0.988	0.012
I05.9 Mitral valve disease, unspecified	0.010	0.990	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.990	0.010
C76.0 Head, face and neck	0.000	0.991	0.009
I05 Rheumatic mitral valve diseases	0.009	0.991	0.000
I05.1 Rheumatic mitral insufficiency	0.009	0.991	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.991	0.009
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.991	0.009
C80 Malignant neoplasm without specification of site	0.000	0.991	0.009
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.991	0.009
R60.0 Localised oedema	0.008	0.992	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.992	0.008
I05.2 Mitral stenosis with insufficiency	0.007	0.992	0.000
I05-I09 Chronic rheumatic heart diseases	0.007	0.993	0.000
I05.8 Other mitral valve diseases	0.007	0.993	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.007	0.993	0.000
I08 Multiple valve diseases	0.007	0.993	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.993	0.007
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.993	0.006
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.993	0.006
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.993	0.006
I08.1 Disorders of both mitral and tricuspid valves	0.006	0.994	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.994	0.006
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.994	0.006
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.994	0.006
Y52.4 Angiotensin-converting-enzyme inhibitors	0.006	0.994	0.000
I09 Other rheumatic heart diseases	0.006	0.994	0.000
D59.1 Other autoimmune haemolytic anaemias	0.006	0.994	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.994	0.006
Y52 Agents primarily affecting the cardiovascular system	0.006	0.994	0.000
K25.3 Acute without haemorrhage or perforation	0.000	0.994	0.006
I09.9 Rheumatic heart disease, unspecified	0.005	0.995	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
M84 Disorders of continuity of bone	0.000	0.995	0.005
I06 Rheumatic aortic valve diseases	0.005	0.995	0.000
M84.0 Malunion of fracture	0.000	0.995	0.005
J38.6 Stenosis of larynx	0.000	0.995	0.005
I07 Rheumatic tricuspid valve diseases	0.005	0.995	0.000
Y45.1 Salicylates	0.000	0.995	0.005
I08.9 Multiple valve disease, unspecified	0.005	0.995	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.005	0.995	0.000
I05.0 Mitral stenosis	0.005	0.995	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.995	0.005
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
F41 Other anxiety disorders	0.005	0.995	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.995	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
F41.1 Generalised anxiety disorder	0.005	0.995	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.995	0.000
I08.8 Other multiple valve diseases	0.005	0.995	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.005	0.995	0.000
I09.8 Other specified rheumatic heart diseases	0.005	0.995	0.000
I09.2 Chronic rheumatic pericarditis	0.005	0.995	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.005	0.995	0.000
I09.0 Rheumatic myocarditis	0.005	0.995	0.000
J38.5 Laryngeal spasm	0.000	0.995	0.005
J38.1 Polyp of vocal cord and larynx	0.000	0.995	0.005
D59 Acquired haemolytic anaemia	0.005	0.995	0.000
J38.2 Nodules of vocal cords	0.000	0.995	0.005
Q25.1 Coarctation of aorta	0.005	0.995	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.995	0.004
M84.02 Malunion of fracture (Upper arm)	0.000	0.995	0.004
J33.9 Nasal polyp, unspecified	0.000	0.996	0.004
M84.06 Malunion of fracture (Lower leg)	0.000	0.996	0.004
I06.9 Rheumatic aortic valve disease, unspecified	0.004	0.996	0.000
Q60-Q64 Congenital malformations of the urinary system	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
M84.8 Other disorders of continuity of bone	0.000	0.996	0.004
M84.04 Malunion of fracture (Hand)	0.000	0.996	0.004
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.004	0.996	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.004	0.996	0.000
N64.8 Other specified disorders of breast	0.000	0.996	0.004
Q18.0 Sinus, fistula and cyst of branchial cleft	0.004	0.996	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.996	0.004
M84.9 Disorder of continuity of bone, unspecified	0.000	0.996	0.004
M84.3 Stress fracture, not elsewhere classified	0.000	0.996	0.004
Q64 Other congenital malformations of urinary system	0.004	0.996	0.000
I06.8 Other rheumatic aortic valve diseases	0.004	0.996	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.004	0.996	0.000
I06.1 Rheumatic aortic insufficiency	0.004	0.996	0.000
M84.09 Malunion of fracture (Site unspecified)	0.000	0.996	0.004
M84.08 Malunion of fracture (Other)	0.000	0.996	0.004
M84.00 Malunion of fracture (Multiple sites)	0.000	0.996	0.004
Y52.7 Peripheral vasodilators	0.004	0.996	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.004	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.004	0.996	0.000
M84.03 Malunion of fracture (Forearm)	0.000	0.996	0.004
I07.9 Tricuspid valve disease, unspecified	0.004	0.996	0.000
I07.8 Other tricuspid valve diseases	0.004	0.996	0.000
I07.2 Tricuspid stenosis with insufficiency	0.004	0.996	0.000
I07.0 Tricuspid stenosis	0.004	0.996	0.000
Q18 Other congenital malformations of face and neck	0.004	0.996	0.000
Q25.4 Other congenital malformations of aorta	0.004	0.996	0.000
Q25.6 Stenosis of pulmonary artery	0.004	0.996	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.004	0.996	0.000
I06.0 Rheumatic aortic stenosis	0.004	0.996	0.000
I07.1 Tricuspid insufficiency	0.004	0.996	0.000
M84.01 Malunion of fracture (Shoulder region)	0.000	0.996	0.004
D59.4 Other nonautoimmune haemolytic anaemias	0.004	0.996	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.004	0.996	0.000
H40.1 Primary open-angle glaucoma	0.004	0.996	0.000
Q15 Other congenital malformations of eye	0.004	0.996	0.000
Q25.3 Stenosis of aorta	0.004	0.996	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.004	0.996	0.000
M84.2 Delayed union of fracture	0.000	0.996	0.004
Q60.0 Renal agenesis, unilateral	0.004	0.996	0.000
Q55 Other congenital malformations of male genital organs	0.004	0.996	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.996	0.004
Q25.0 Patent ductus arteriosus	0.004	0.996	0.000
F41.3 Other mixed anxiety disorders	0.004	0.996	0.000
Q21 Congenital malformations of cardiac septa	0.004	0.996	0.000
Q54 Hypospadias	0.004	0.996	0.000
Q80-Q89 Other congenital malformations	0.004	0.996	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.004	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.004	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.004	0.996	0.000
Q25.2 Atresia of aorta	0.004	0.996	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.004	0.996	0.000
K62.8 Other specified diseases of anus and rectum	0.000	0.996	0.004
Q53 Undescended testicle	0.004	0.996	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.996	0.004
Q15.0 Congenital glaucoma	0.004	0.996	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.004	0.996	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.004	0.996	0.000
M84.4 Pathological fracture, not elsewhere classified	0.000	0.996	0.004
Q63 Other congenital malformations of kidney	0.004	0.996	0.000
Q23 Congenital malformations of aortic and mitral valves	0.004	0.996	0.000
D59.8 Other acquired haemolytic anaemias	0.003	0.996	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.003	0.996	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.003	0.996	0.000
D59.3 Haemolytic-uraemic syndrome	0.003	0.996	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.003	0.996	0.000
J38.0 Paralysis of vocal cords and larynx	0.000	0.996	0.004
Q21.1 Atrial septal defect	0.004	0.996	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.996	0.000
Q51 Congenital malformations of uterus and cervix	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.996	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.004	0.996	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.996	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.996	0.003
K06.0 Gingival recession	0.003	0.996	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.997	0.000
Q61 Cystic kidney disease	0.003	0.997	0.000
F41.8 Other specified anxiety disorders	0.003	0.997	0.000
N76.6 Ulceration of vulva	0.000	0.997	0.003
C71.1 Frontal lobe	0.000	0.997	0.003
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
Q12 Congenital lens malformations	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.997	0.003
M84.88 Other disorders of continuity of bone (Other)	0.000	0.997	0.003
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.997	0.003
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.997	0.003
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.997	0.003
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.997	0.003
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.997	0.003
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.997	0.003
Q21.9 Congenital malformation of cardiac septum, unspecified	0.003	0.997	0.000
Q55.6 Other congenital malformations of penis	0.003	0.997	0.000
Q51.2 Other doubling of uterus	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.997	0.003
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.997	0.000
Q61.4 Renal dysplasia	0.003	0.997	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.003	0.997	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.997	0.003
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.997	0.003
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.997	0.003
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.997	0.003
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.003
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.997	0.003
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.997	0.003
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.997	0.003
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.997	0.003
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.997	0.003
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.997	0.003
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.997	0.003
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.997	0.003
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.997	0.003
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.997	0.003
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.997	0.003
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.997	0.003
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.997	0.003
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.997	0.003
Q64.9 Congenital malformation of urinary system, unspecified	0.003	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.003	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.003	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.003	0.997	0.000
Q64.4 Malformation of urachus	0.003	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.003	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.003	0.997	0.000
Q64.0 Epispadias	0.003	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
Q63.8 Other specified congenital malformations of kidney	0.003	0.997	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.997	0.000
Q54.0 Hypospadias, balanic	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.003	0.997	0.000
Q18.8 Other specified congenital malformations of face and neck	0.003	0.997	0.000
Q18.7 Microcheilia	0.003	0.997	0.000
Q18.6 Macrocheilia	0.003	0.997	0.000
Q18.5 Microstomia	0.003	0.997	0.000
Q18.4 Macrostomia	0.003	0.997	0.000
Q18.3 Webbing of neck	0.003	0.997	0.000
Q18.2 Other branchial cleft malformations	0.003	0.997	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.003	0.997	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.003	0.997	0.000
Q54.9 Hypospadias, unspecified	0.003	0.997	0.000
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.003	0.997	0.000
Q53.1 Undescended testicle, unilateral	0.003	0.997	0.000
Q60.6 Potter's syndrome	0.003	0.997	0.000
Q60.5 Renal hypoplasia, unspecified	0.003	0.997	0.000
Q60.4 Renal hypoplasia, bilateral	0.003	0.997	0.000
Q60.3 Renal hypoplasia, unilateral	0.003	0.997	0.000
Q60.1 Renal agenesis, bilateral	0.003	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
Q89 Other congenital malformations, not elsewhere classified	0.003	0.997	0.000
Q15.9 Congenital malformation of eye, unspecified	0.003	0.997	0.000
Q15.8 Other specified congenital malformations of eye	0.003	0.997	0.000
Q54.1 Hypospadias, penile	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.997	0.003
M84.28 Delayed union of fracture (Other)	0.000	0.997	0.003
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.997	0.003
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.997	0.003
M84.24 Delayed union of fracture (Hand)	0.000	0.997	0.003
M84.23 Delayed union of fracture (Forearm)	0.000	0.997	0.003
M84.22 Delayed union of fracture (Upper arm)	0.000	0.997	0.003
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.997	0.003
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.997	0.003
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.997	0.003
J38.4 Oedema of larynx	0.000	0.997	0.003
Q53.9 Undescended testicle, unspecified	0.003	0.997	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.003	0.997	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.003	0.997	0.000
Q55.5 Congenital absence and aplasia of penis	0.003	0.997	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.003	0.997	0.000
Q55.3 Atresia of vas deferens	0.003	0.997	0.000
Q55.1 Hypoplasia of testis and scrotum	0.003	0.997	0.000
Q55.0 Absence and aplasia of testis	0.003	0.997	0.000
Q53.2 Undescended testicle, bilateral	0.003	0.997	0.000
Q21.8 Other congenital malformations of cardiac septa	0.003	0.997	0.000
Q21.4 Aortopulmonary septal defect	0.003	0.997	0.000
Q21.2 Atrioventricular septal defect	0.003	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.003	0.997	0.000
Q84 Other congenital malformations of integument	0.003	0.997	0.000
Q81 Epidermolysis bullosa	0.003	0.997	0.000
Q80 Congenital ichthyosis	0.003	0.997	0.000
Q54.4 Congenital chordee	0.003	0.997	0.000
Q54.3 Hypospadias, perineal	0.003	0.997	0.000
Q54.2 Hypospadias, penoscrotal	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.003	0.997	0.000
Q63.2 Ectopic kidney	0.003	0.997	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.003	0.997	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.997	0.003
K06.1 Gingival enlargement	0.003	0.997	0.000
Q53.0 Ectopic testis	0.003	0.997	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.003	0.997	0.000
Q87.4 Marfan's syndrome	0.003	0.997	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.997	0.003
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.997	0.003
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.997	0.003
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.997	0.003
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.997	0.003
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.997	0.003
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.997	0.003
I08.0 Disorders of both mitral and aortic valves	0.003	0.997	0.000
Q60.2 Renal agenesis, unspecified	0.003	0.997	0.000
G31.0 Circumscribed brain atrophy	0.000	0.997	0.003
Q28.0 Arteriovenous malformation of precerebral vessels	0.003	0.997	0.000
Q61.9 Cystic kidney disease, unspecified	0.003	0.997	0.000
Q63.3 Hyperplastic and giant kidney	0.003	0.997	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.003	0.997	0.000
Q14.1 Congenital malformation of retina	0.003	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
Q61.5 Medullary cystic kidney	0.003	0.997	0.000
L73.9 Follicular disorder, unspecified	0.000	0.997	0.003
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
Q18.1 Preauricular sinus and cyst	0.003	0.997	0.000
Q54.8 Other hypospadias	0.003	0.997	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.003	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.003	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.003	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.003	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.003	0.997	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.003	0.997	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.003	0.997	0.000
Q98.7 Male with sex chromosome mosaicism	0.003	0.997	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.003	0.997	0.000
Q98.5 Karyotype 47,XYY	0.003	0.997	0.000
Q98.3 Other male with 46,XX karyotype	0.003	0.997	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.003	0.997	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.003	0.997	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.003	0.997	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.000	0.997	0.003
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.997	0.003
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
Q83 Congenital malformations of breast	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
N94.1 Dyspareunia	0.003	0.997	0.000
Q82 Other congenital malformations of skin	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
Q23.0 Congenital stenosis of aortic valve	0.003	0.997	0.000
Q52.4 Other congenital malformations of vagina	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.003	0.997	0.000
Q12.0 Congenital cataract	0.003	0.997	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.997	0.003
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.003	0.997	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q14.3 Congenital malformation of choroid	0.003	0.997	0.000
Q14.2 Congenital malformation of optic disk	0.003	0.997	0.000
Q14.0 Congenital malformation of vitreous humour	0.003	0.997	0.000
Q61.8 Other cystic kidney diseases	0.003	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.003	0.997	0.000
Q52.1 Doubling of vagina	0.003	0.997	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.003	0.997	0.000
M84.26 Delayed union of fracture (Lower leg)	0.000	0.997	0.002
Q12.9 Congenital lens malformation, unspecified	0.003	0.997	0.000
Q12.8 Other congenital lens malformations	0.003	0.997	0.000
Q12.4 Spherophakia	0.003	0.997	0.000
Q12.3 Congenital aphakia	0.003	0.997	0.000
Q12.2 Coloboma of lens	0.003	0.997	0.000
Q12.1 Congenital displaced lens	0.003	0.997	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.997	0.000
Q20.4 Double inlet ventricle	0.002	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.997	0.000
Q20.2 Double outlet left ventricle	0.002	0.997	0.000
Q20.1 Double outlet right ventricle	0.002	0.997	0.000
Q20.0 Common arterial trunk	0.002	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.1 Persistent left superior vena cava	0.002	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.997	0.000
Q28.3 Other malformations of cerebral vessels	0.003	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.997	0.000
Q51.4 Unicornate uterus	0.003	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
Q21.0 Ventricular septal defect	0.003	0.997	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.997	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.997	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.997	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.997	0.000
Q05 Spina bifida	0.003	0.997	0.000
Q36 Cleft lip	0.002	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
Q11.3 Macrophthalmos	0.002	0.997	0.000
Q11.2 Microphthalmos	0.002	0.997	0.000
Q11.1 Other anophthalmos	0.002	0.997	0.000
Q11.0 Cystic eyeball	0.002	0.997	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.002	0.997	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.002	0.997	0.000
Q13.5 Blue sclera	0.002	0.997	0.000
Q13.4 Other congenital corneal malformations	0.002	0.997	0.000
Q13.3 Congenital corneal opacity	0.002	0.997	0.000
Q13.2 Other congenital malformations of iris	0.002	0.997	0.000
Q13.1 Absence of iris	0.002	0.997	0.000
Q13.0 Coloboma of iris	0.002	0.997	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.002	0.997	0.000
Q16.5 Congenital malformation of inner ear	0.002	0.997	0.000
Q16.4 Other congenital malformations of middle ear	0.002	0.997	0.000
Q16.3 Congenital malformation of ear ossicles	0.002	0.997	0.000
Q16.2 Absence of eustachian tube	0.002	0.997	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.002	0.997	0.000
Q16.0 Congenital absence of (ear) auricle	0.002	0.997	0.000
Q85.1 Tuberous sclerosis	0.002	0.997	0.000
S12.1 Fracture of second cervical vertebra	0.000	0.997	0.003
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.002	0.997	0.000
Q50.3 Other congenital malformations of ovary	0.002	0.997	0.000
Q50.2 Congenital torsion of ovary	0.002	0.997	0.000
Q50.1 Developmental ovarian cyst	0.002	0.997	0.000
Q50.0 Congenital absence of ovary	0.002	0.997	0.000
Q51.3 Bicornate uterus	0.003	0.997	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.997	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.997	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.997	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.997	0.000
Q52.3 Imperforate hymen	0.002	0.997	0.000
Q52.2 Congenital rectovaginal fistula	0.002	0.997	0.000
Q52.0 Congenital absence of vagina	0.002	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.997	0.000
Q33 Congenital malformations of lung	0.002	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.997	0.000
Q31 Congenital malformations of larynx	0.002	0.997	0.000
Q30 Congenital malformations of nose	0.002	0.997	0.000
Q50.5 Embryonic cyst of broad ligament	0.002	0.997	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.002	0.997	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.002	0.997	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.002	0.997	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.002
Q89.2 Congenital malformations of other endocrine glands	0.003	0.997	0.000
Q90 Down's syndrome	0.002	0.997	0.000
Q17.9 Congenital malformation of ear, unspecified	0.002	0.997	0.000
Q17.8 Other specified congenital malformations of ear	0.002	0.997	0.000
Q17.4 Misplaced ear	0.002	0.997	0.000
Q17.3 Other misshapen ear	0.002	0.997	0.000
Q17.2 Microtia	0.002	0.997	0.000
Q17.1 Macrotia	0.002	0.997	0.000
Q17.0 Accessory auricle	0.002	0.997	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.002	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.002	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.002	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.002	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.002	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.002	0.997	0.000
Q22.0 Pulmonary valve atresia	0.002	0.997	0.000
Q03 Congenital hydrocephalus	0.002	0.997	0.000
Q96 Turner's syndrome	0.002	0.997	0.000
Q35 Cleft palate	0.002	0.997	0.000
K75.4 Autoimmune hepatitis	0.000	0.997	0.003
Q21.3 Tetralogy of Fallot	0.002	0.997	0.000
N80.9 Endometriosis, unspecified	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.002	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.002	0.997	0.000
Q62.6 Malposition of ureter	0.002	0.997	0.000
Q62.4 Agenesis of ureter	0.002	0.997	0.000
Q62.2 Congenital megaloureter	0.002	0.997	0.000
Q62.1 Atresia and stenosis of ureter	0.002	0.997	0.000
Q62.0 Congenital hydronephrosis	0.002	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.997	0.000
Q17.5 Prominent ear	0.002	0.997	0.000
Q22.1 Congenital pulmonary valve stenosis	0.002	0.997	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.997	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.002	0.997	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.997	0.003
Q22.5 Ebstein's anomaly	0.002	0.997	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.002	0.997	0.000
Q82.0 Hereditary lymphoedema	0.002	0.997	0.000
Q89.9 Congenital malformation, unspecified	0.002	0.997	0.000
Q89.8 Other specified congenital malformations	0.002	0.997	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.002	0.997	0.000
Q89.4 Conjoined twins	0.002	0.997	0.000
Q89.1 Congenital malformations of adrenal gland	0.002	0.997	0.000
Q89.0 Congenital malformations of spleen	0.002	0.997	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.998	0.002
Q10.7 Congenital malformation of orbit	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations