TreeWAS – Variant ID: rs16853722

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I44.2 Atrioventricular block, complete	0.043	0.957	0.000
L85.9 Epidermal thickening, unspecified	0.027	0.973	0.000
R40.0 Somnolence	0.026	0.974	0.000
G47.9 Sleep disorder, unspecified	0.025	0.975	0.000
I42.0 Dilated cardiomyopathy	0.016	0.984	0.000
R40 Somnolence, stupor and coma	0.015	0.985	0.000
G47 Sleep disorders	0.014	0.986	0.000
I86.1 Scrotal varices	0.013	0.987	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.012	0.988	0.000
L85 Other epidermal thickening	0.012	0.988	0.000
I42 Cardiomyopathy	0.011	0.989	0.000
R00.2 Palpitations	0.000	0.989	0.011
R40.2 Coma, unspecified	0.011	0.989	0.000
G47.3 Sleep apnoea	0.011	0.989	0.000
R40.1 Stupor	0.011	0.989	0.000
G47.2 Disorders of the sleep-wake schedule	0.010	0.990	0.000
I42.2 Other hypertrophic cardiomyopathy	0.010	0.990	0.000
R79.0 Abnormal level of blood mineral	0.010	0.990	0.000
I42.6 Alcoholic cardiomyopathy	0.010	0.990	0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.009	0.990	0.000
I86.8 Varicose veins of other specified sites	0.010	0.990	0.000
I86 Varicose veins of other sites	0.009	0.991	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.009	0.991	0.000
G47.4 Narcolepsy and cataplexy	0.009	0.991	0.000
Z34.0 Supervision of normal first pregnancy	0.009	0.991	0.000
R79.8 Other specified abnormal findings of blood chemistry	0.009	0.991	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.009	0.991	0.000
G47.8 Other sleep disorders	0.009	0.991	0.000
L85.3 Xerosis cutis	0.009	0.991	0.000
L85.2 Keratosis punctata (palmaris et plantaris)	0.009	0.991	0.000
L85.0 Acquired ichthyosis	0.009	0.991	0.000
R79 Other abnormal findings of blood chemistry	0.009	0.991	0.000
I42.9 Cardiomyopathy, unspecified	0.008	0.991	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.008	0.992	0.000
I42.5 Other restrictive cardiomyopathy	0.008	0.992	0.000
I42.4 Endocardial fibroelastosis	0.008	0.992	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.008	0.992	0.000
H65.3 Chronic mucoid otitis media	0.000	0.992	0.008
L85.8 Other specified epidermal thickening	0.008	0.992	0.000
R44.3 Hallucinations, unspecified	0.008	0.992	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.008	0.992	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.007	0.993	0.000
I42.8 Other cardiomyopathies	0.007	0.993	0.000
R01.1 Cardiac murmur, unspecified	0.000	0.993	0.007
I86.3 Vulval varices	0.007	0.993	0.000
I86.2 Pelvic varices	0.007	0.993	0.000
I86.0 Sublingual varices	0.007	0.993	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.007	0.993	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.007	0.993	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.007	0.993	0.000
R44.1 Visual hallucinations	0.007	0.993	0.000
Z34 Supervision of normal pregnancy	0.006	0.994	0.000
I86.4 Gastric varices	0.006	0.994	0.000
M25.84 Other specified joint disorders (Hand)	0.006	0.994	0.000
R44.2 Other hallucinations	0.006	0.994	0.000
R45 Symptoms and signs involving emotional state	0.006	0.994	0.000
R46 Symptoms and signs involving appearance and behaviour	0.006	0.994	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.994	0.006
R74 Abnormal serum enzyme levels	0.006	0.994	0.000
R78 Findings of drugs and other substances, not normally found in blood	0.006	0.994	0.000
R43 Disturbances of smell and taste	0.006	0.994	0.000
R44.0 Auditory hallucinations	0.005	0.994	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.005	0.995	0.000
R77 Other abnormalities of plasma proteins	0.005	0.995	0.000
R76 Other abnormal immunological findings in serum	0.005	0.995	0.000
R46.4 Slowness and poor responsiveness	0.005	0.995	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.005	0.995	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.005	0.995	0.000
R01.0 Benign and innocent cardiac murmurs	0.000	0.995	0.005
R01 Cardiac murmurs and other cardiac sounds	0.000	0.995	0.005
R43.0 Anosmia	0.005	0.995	0.000
R45.1 Restlessness and agitation	0.005	0.995	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.005	0.995	0.000
D47.1 Chronic myeloproliferative disease	0.005	0.995	0.000
O80.9 Single spontaneous delivery, unspecified	0.000	0.995	0.005
R78.0 Finding of alcohol in blood	0.005	0.995	0.000
R45.5 Hostility	0.005	0.995	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.005	0.995	0.000
R78.8 Finding of other specified substances, not normally found in blood	0.005	0.995	0.000
R71 Abnormality of red blood cells	0.005	0.995	0.000
R45.6 Physical violence	0.005	0.995	0.000
Z02.8 Other examinations for administrative purposes	0.000	0.995	0.005
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.005	0.995	0.000
R45.2 Unhappiness	0.005	0.995	0.000
R46.2 Strange and inexplicable behaviour	0.004	0.995	0.000
R77.9 Abnormality of plasma protein, unspecified	0.005	0.995	0.000
R74.8 Abnormal levels of other serum enzymes	0.005	0.995	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.005	0.995	0.000
M25.8 Other specified joint disorders	0.005	0.995	0.000
R45.7 State of emotional shock and stress, unspecified	0.004	0.995	0.000
R45.3 Demoralisation and apathy	0.004	0.995	0.000
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.004	0.995	0.000
R46.6 Undue concern and preoccupation with stressful events	0.004	0.995	0.000
R46.5 Suspiciousness and marked evasiveness	0.004	0.995	0.000
R46.3 Overactivity	0.004	0.995	0.000
R46.1 Bizarre personal appearance	0.004	0.995	0.000
R46.0 Very low level of personal hygiene	0.004	0.995	0.000
R45.4 Irritability and anger	0.004	0.996	0.000
R78.9 Finding of unspecified substance, not normally found in blood	0.004	0.996	0.000
R78.7 Finding of abnormal level of heavy metals in blood	0.004	0.996	0.000
R78.6 Finding of steroid agent in blood	0.004	0.996	0.000
R78.5 Finding of psychotropic drug in blood	0.004	0.996	0.000
R78.4 Finding of other drugs of addictive potential in blood	0.004	0.996	0.000
R78.3 Finding of hallucinogen in blood	0.004	0.996	0.000
R78.2 Finding of cocaine in blood	0.004	0.996	0.000
R78.1 Finding of opiate drug in blood	0.004	0.996	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.004	0.996	0.000
R43.2 Parageusia	0.004	0.996	0.000
R43.1 Parosmia	0.004	0.996	0.000
R45.0 Nervousness	0.004	0.996	0.000
N21.0 Calculus in bladder	0.000	0.996	0.004
M25.88 Other specified joint disorders (Other)	0.004	0.996	0.000
M25.86 Other specified joint disorders (Lower leg)	0.004	0.996	0.000
R76.8 Other specified abnormal immunological findings in serum	0.004	0.996	0.000
Y57.9 Drug or medicament, unspecified	0.004	0.996	0.000
R77.2 Abnormality of alphafetoprotein	0.004	0.996	0.000
R77.1 Abnormality of globulin	0.004	0.996	0.000
R77.0 Abnormality of albumin	0.004	0.996	0.000
J06.9 Acute upper respiratory infection, unspecified	0.000	0.996	0.004
R45.8 Other symptoms and signs involving emotional state	0.004	0.996	0.000
R76.9 Abnormal immunological finding in serum, unspecified	0.004	0.996	0.000
R76.2 False-positive serological test for syphilis	0.004	0.996	0.000
R76.1 Abnormal reaction to tuberculin test	0.004	0.996	0.000
R76.0 Raised antibody titer	0.004	0.996	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.004	0.996	0.000
R70.1 Abnormal plasma viscosity	0.004	0.996	0.000
R01.2 Other cardiac sounds	0.000	0.996	0.004
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.004	0.996	0.000
D47.4 Osteomyelofibrosis	0.004	0.996	0.000
Z34.8 Supervision of other normal pregnancy	0.004	0.996	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.004	0.996	0.000
S52.0 Fracture of upper end of ulna	0.000	0.996	0.004
M25.81 Other specified joint disorders (Shoulder region)	0.004	0.996	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.996	0.004
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.003	0.996	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.003	0.996	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.003	0.996	0.000
R77.8 Other specified abnormalities of plasma proteins	0.003	0.996	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.004	0.996	0.000
M25.83 Other specified joint disorders (Forearm)	0.003	0.996	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.003	0.996	0.000
M25.82 Other specified joint disorders (Upper arm)	0.003	0.996	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.003	0.996	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.003	0.996	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.003	0.996	0.000
D47.2 Monoclonal gammopathy	0.003	0.996	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.003	0.997	0.000
D45 Polycythaemia vera	0.003	0.997	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.003	0.997	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.003	0.997	0.000
D46 Myelodysplastic syndromes	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.003	0.997	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.003	0.997	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.997	0.003
R41.2 Retrograde amnesia	0.003	0.997	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.003	0.997	0.000
S52.1 Fracture of upper end of radius	0.000	0.997	0.003
M85.8 Other specified disorders of bone density and structure	0.003	0.997	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.003	0.997	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.003	0.997	0.000
R73 Elevated blood glucose level	0.003	0.997	0.000
K05.3 Chronic periodontitis	0.000	0.997	0.003
S52 Fracture of forearm	0.000	0.997	0.003
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.003	0.997	0.000
I44 Atrioventricular and left bundle-branch block	0.003	0.997	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.003	0.997	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.003	0.997	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.003	0.997	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.003	0.997	0.000
H90 Conductive and sensorineural hearing loss	0.003	0.997	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.003	0.997	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.003	0.997	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.997	0.003
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.003	0.997	0.000
D41.0 Kidney	0.003	0.997	0.000
D43.0 Brain, supratentorial	0.003	0.997	0.000
M31.6 Other giant cell arteritis	0.003	0.997	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.003	0.997	0.000
G57.6 Lesion of plantar nerve	0.000	0.997	0.003
R41.1 Anterograde amnesia	0.003	0.997	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.002	0.997	0.000
S52.51 Fracture of lower end of radius (open)	0.000	0.997	0.003
D38.0 Larynx	0.003	0.997	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.003	0.997	0.000
D46.7 Other myelodysplastic syndromes	0.002	0.997	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.002	0.997	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.002	0.997	0.000
D46.4 Refractory anaemia, unspecified	0.002	0.997	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.002	0.997	0.000
D46.1 Refractory anaemia with sideroblasts	0.002	0.997	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.002	0.997	0.000
D39.7 Other female genital organs	0.002	0.997	0.000
D48.0 Bone and articular cartilage	0.003	0.997	0.000
S52.8 Fracture of other parts of forearm	0.000	0.997	0.003
S52.11 Fracture of upper end of radius (open)	0.000	0.997	0.002
D48.7 Other specified sites	0.003	0.997	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.002	0.997	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.002	0.997	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.002	0.997	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.997	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.002	0.997	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.002	0.997	0.000
D43.4 Spinal cord	0.002	0.997	0.000
F40.2 Specific (isolated) phobias	0.003	0.997	0.000
D44.4 Craniopharyngeal duct	0.002	0.997	0.000
H90.0 Conductive hearing loss, bilateral	0.002	0.997	0.000
N21 Calculus of lower urinary tract	0.000	0.997	0.003
S52.5 Fracture of lower end of radius	0.000	0.997	0.002
R20.2 Paraesthesia of skin	0.000	0.998	0.002
S52.2 Fracture of shaft of ulna	0.000	0.998	0.002
M25.37 Other instability of joint (Ankle and foot)	0.002	0.998	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.998	0.000
D46.2 Refractory anaemia with excess of blasts	0.002	0.998	0.000
D43.9 Central nervous system, unspecified	0.002	0.998	0.000
D43.7 Other parts of central nervous system	0.002	0.998	0.000
D43.3 Cranial nerves	0.002	0.998	0.000
D43.1 Brain, infratentorial	0.002	0.998	0.000
D44.6 Carotid body	0.002	0.998	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
D48.6 Breast	0.002	0.998	0.000
D39.0 Uterus	0.002	0.998	0.000
N21.1 Calculus in urethra	0.000	0.998	0.002
M25.36 Other instability of joint (Lower leg)	0.002	0.998	0.000
S52.80 Fracture of other parts of forearm (closed)	0.000	0.998	0.002
D39.9 Female genital organ, unspecified	0.002	0.998	0.000
D39.2 Placenta	0.002	0.998	0.000
S52.4 Fracture of shafts of both ulna and radius	0.000	0.998	0.002
D03.4 Melanoma in situ of scalp and neck	0.002	0.998	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.002	0.998	0.000
S52.9 Fracture of forearm, part unspecified	0.000	0.998	0.002
H65 Nonsuppurative otitis media	0.000	0.998	0.002
D38.6 Respiratory organ, unspecified	0.002	0.998	0.000
D38.5 Other respiratory organs	0.002	0.998	0.000
D38.4 Thymus	0.002	0.998	0.000
D38.3 Mediastinum	0.002	0.998	0.000
D38.2 Pleura	0.002	0.998	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
I44.5 Left posterior fascicular block	0.002	0.998	0.000
I44.4 Left anterior fascicular block	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.000	0.998	0.002
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.002	0.998	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.002	0.998	0.000
D40.0 Prostate	0.002	0.998	0.000
D44.9 Endocrine gland, unspecified	0.002	0.998	0.000
D44.8 Pluriglandular involvement	0.002	0.998	0.000
D44.7 Aortic body and other paraganglia	0.002	0.998	0.000
D44.5 Pineal gland	0.002	0.998	0.000
D44.2 Parathyroid gland	0.002	0.998	0.000
D44.1 Adrenal gland	0.002	0.998	0.000
D40.9 Male genital organ, unspecified	0.002	0.998	0.000
D40.7 Other male genital organs	0.002	0.998	0.000
D41.2 Ureter	0.002	0.998	0.000
I44.3 Other and unspecified atrioventricular block	0.002	0.998	0.000
M25.3 Other instability of joint	0.002	0.998	0.000
D41.9 Urinary organ, unspecified	0.002	0.998	0.000
D41.7 Other urinary organs	0.002	0.998	0.000
D41.3 Urethra	0.002	0.998	0.000
D41.1 Renal pelvis	0.002	0.998	0.000
D42.9 Meninges, unspecified	0.002	0.998	0.000
D42.1 Spinal meninges	0.002	0.998	0.000
D42.0 Cerebral meninges	0.002	0.998	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.998	0.002
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.998	0.002
S52.01 Fracture of upper end of ulna (open)	0.000	0.998	0.002
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
D40.1 Testis	0.002	0.998	0.000
I84.2 Internal haemorrhoids without complication	0.000	0.998	0.002
S68 Traumatic amputation of wrist and hand	0.002	0.998	0.000
D39.1 Ovary	0.002	0.998	0.000
D44.0 Thyroid gland	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.998	0.002
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.002	0.998	0.000
R41.0 Disorientation, unspecified	0.002	0.998	0.000
S52.3 Fracture of shaft of radius	0.000	0.998	0.002
D13.2 Duodenum	0.000	0.998	0.002
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.002	0.998	0.000
D48.4 Peritoneum	0.002	0.998	0.000
D48.3 Retroperitoneum	0.002	0.998	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
S52.7 Multiple fractures of forearm	0.000	0.998	0.002
I44.1 Atrioventricular block, second degree	0.002	0.998	0.000
D03 Melanoma in situ	0.002	0.998	0.000
O80 Single spontaneous delivery	0.000	0.998	0.002
D68.9 Coagulation defect, unspecified	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
C16.9 Stomach, unspecified	0.002	0.998	0.000
K90.0 Coeliac disease	0.002	0.998	0.000
S52.20 Fracture of shaft of ulna (closed)	0.000	0.998	0.002
S52.81 Fracture of other parts of forearm (open)	0.000	0.998	0.002
D43.2 Brain, unspecified	0.002	0.998	0.000
D68.8 Other specified coagulation defects	0.002	0.998	0.000
D44.3 Pituitary gland	0.002	0.998	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.000	0.998	0.002
N21.8 Other lower urinary tract calculus	0.000	0.998	0.002
D03.7 Melanoma in situ of lower limb, including hip	0.002	0.998	0.000
H90.3 Sensorineural hearing loss, bilateral	0.002	0.998	0.000
S52.21 Fracture of shaft of ulna (open)	0.000	0.998	0.002
I44.6 Other and unspecified fascicular block	0.002	0.998	0.000
K85.1 Biliary acute pancreatitis	0.002	0.998	0.000
Z02 Examination and encounter for administrative purposes	0.000	0.998	0.002
S52.40 Fracture of shafts of both ulna and radius (closed)	0.000	0.998	0.002
S68.0 Traumatic amputation of thumb (complete)(partial)	0.002	0.998	0.000
S52.41 Fracture of shafts of both ulna and radius (open)	0.000	0.998	0.002
D38.1 Trachea, bronchus and lung	0.002	0.998	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.998	0.002
S52.91 Fracture of forearm, part unspecified (open)	0.000	0.998	0.002
S52.90 Fracture of forearm, part unspecified (closed)	0.000	0.998	0.002
R73.0 Abnormal glucose tolerance test	0.002	0.998	0.000
M25.39 Other instability of joint (Site unspecified)	0.002	0.998	0.000
M25.38 Other instability of joint (Other)	0.002	0.998	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.002	0.998	0.000
M25.33 Other instability of joint (Forearm)	0.002	0.998	0.000
M25.32 Other instability of joint (Upper arm)	0.002	0.998	0.000
M25.30 Other instability of joint (Multiple sites)	0.002	0.998	0.000
C16.3 Pyloric antrum	0.002	0.998	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.000	0.998	0.002
M25.34 Other instability of joint (Hand)	0.002	0.998	0.000
S52.31 Fracture of shaft of radius (open)	0.000	0.998	0.002
H33.5 Other retinal detachments	0.002	0.998	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.002	0.998	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.002	0.998	0.000
S68.4 Traumatic amputation of hand at wrist level	0.002	0.998	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.002	0.998	0.000
S52.71 Multiple fractures of forearm (open)	0.000	0.998	0.002
M25.31 Other instability of joint (Shoulder region)	0.002	0.998	0.000
D03.9 Melanoma in situ, unspecified	0.002	0.998	0.000
D03.8 Melanoma in situ of other sites	0.002	0.998	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.002	0.998	0.000
D03.0 Melanoma in situ of lip	0.002	0.998	0.000
O80.1 Spontaneous breech delivery	0.000	0.998	0.002
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.998	0.002
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.002	0.998	0.000
D68 Other coagulation defects	0.002	0.998	0.000
M25.9 Joint disorder, unspecified	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.000	0.998	0.002
O80.8 Other single spontaneous delivery	0.000	0.998	0.002
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
C16.5 Lesser curvature of stomach, unspecified	0.002	0.998	0.000
D37.9 Digestive organ, unspecified	0.002	0.998	0.000
M67.8 Other specified disorders of synovium and tendon	0.002	0.998	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.002	0.998	0.000
H33.2 Serous retinal detachment	0.002	0.998	0.000
S52.6 Fracture of lower end of both ulna and radius	0.000	0.998	0.002
D37.2 Small intestine	0.002	0.998	0.000
H65.2 Chronic serous otitis media	0.000	0.998	0.002
S52.30 Fracture of shaft of radius (closed)	0.000	0.998	0.002
M25 Other joint disorders, not elsewhere classified	0.002	0.998	0.000
S22.40 Multiple fractures of ribs (closed)	0.002	0.998	0.000
S52.70 Multiple fractures of forearm (closed)	0.000	0.998	0.002
D03.6 Melanoma in situ of upper limb, including shoulder	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.002	0.998	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.002	0.998	0.000
S20.2 Contusion of thorax	0.002	0.998	0.000
Z22.3 Carrier of other specified bacterial diseases	0.000	0.998	0.002
M25.99 Joint disorder, unspecified (Site unspecified)	0.002	0.998	0.000
D37.1 Stomach	0.002	0.998	0.000
M50.2 Other cervical disk displacement	0.002	0.998	0.000
Z02.9 Examination for administrative purposes, unspecified	0.000	0.998	0.002
Z02.7 Issue of medical certificate	0.000	0.998	0.002
Z02.6 Examination for insurance purposes	0.000	0.998	0.002
Z02.5 Examination for participation in sport	0.000	0.998	0.002
Z02.4 Examination for driving licence	0.000	0.998	0.002
Z02.3 Examination for recruitment to armed forces	0.000	0.998	0.002
Z02.2 Examination for admission to residential institution	0.000	0.998	0.002
Z02.1 Pre-employment examination	0.000	0.998	0.002
Z02.0 Examination for admission to educational institution	0.000	0.998	0.002
M31 Other necrotising vasculopathies	0.002	0.998	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.002	0.998	0.000
F01.9 Vascular dementia, unspecified	0.002	0.998	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.002	0.998	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.998	0.002
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
D37.3 Appendix	0.002	0.998	0.000
C16 Malignant neoplasm of stomach	0.002	0.998	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.002	0.998	0.000
K05.6 Periodontal disease, unspecified	0.000	0.998	0.002
J06.8 Other acute upper respiratory infections of multiple sites	0.000	0.998	0.001
J06.0 Acute laryngopharyngitis	0.000	0.998	0.001
O14.1 Severe preeclampsia	0.000	0.998	0.002
H65.0 Acute serous otitis media	0.000	0.998	0.001
D05.9 Carcinoma in situ of breast, unspecified	0.002	0.998	0.000
D48.5 Skin	0.001	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.001	0.998	0.000
D68.1 Hereditary factor XI deficiency	0.001	0.998	0.000
M25.98 Joint disorder, unspecified (Other)	0.001	0.998	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.001	0.998	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.001	0.998	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.001	0.998	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.001	0.998	0.000
C16.6 Greater curvature of stomach, unspecified	0.002	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.998	0.000
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
M67.1 Other contracture of tendon (sheath)	0.002	0.998	0.000
M25.0 Haemarthrosis	0.002	0.998	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.998	0.002
O16 Unspecified maternal hypertension	0.000	0.998	0.002
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.002	0.998	0.000
M79.67 Pain in limb (Ankle and foot)	0.000	0.998	0.002
D32.0 Cerebral meninges	0.000	0.998	0.002
H90.2 Conductive hearing loss, unspecified	0.001	0.998	0.000
Z82.3 Family history of stroke	0.000	0.998	0.002
R20 Disturbances of skin sensation	0.000	0.998	0.002
M25.94 Joint disorder, unspecified (Hand)	0.001	0.998	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.998	0.002
M25.6 Stiffness of joint, not elsewhere classified	0.001	0.998	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.001	0.998	0.000
D41.4 Bladder	0.002	0.998	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.002	0.998	0.000
M25.2 Flail joint	0.001	0.998	0.000
M25.1 Fistula of joint	0.001	0.998	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.001	0.998	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.001	0.998	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.001	0.998	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.001	0.998	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.001	0.998	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.001	0.998	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.001	0.998	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.001	0.998	0.000
K05 Gingivitis and periodontal diseases	0.000	0.998	0.002
M31.3 Wegener's granulomatosis	0.001	0.998	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.000	0.998	0.001
C49.3 Connective and soft tissue of thorax	0.001	0.998	0.000
M31.9 Necrotising vasculopathy, unspecified	0.001	0.998	0.000
M31.8 Other specified necrotising vasculopathies	0.001	0.998	0.000
M31.7 Microscopic polyangiitis	0.001	0.998	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.001	0.998	0.000
M31.2 Lethal midline granuloma	0.001	0.998	0.000
M31.1 Thrombotic microangiopathy	0.001	0.998	0.000
M31.0 Hypersensitivity angiitis	0.001	0.998	0.000
N30.3 Trigonitis	0.000	0.998	0.002
C16.8 Overlapping lesion of stomach	0.001	0.998	0.000
C16.4 Pylorus	0.001	0.998	0.000
C16.1 Fundus of stomach	0.001	0.998	0.000
D68.5 Primary Thrombophilia	0.001	0.998	0.000
M67 Other disorders of synovium and tendon	0.001	0.998	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.001	0.999	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.001	0.999	0.000
C16.2 Body of stomach	0.001	0.999	0.000
D37.7 Other digestive organs	0.001	0.999	0.000
H33.3 Retinal breaks without detachment	0.001	0.999	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.999	0.001
M25.06 Haemarthrosis (Lower leg)	0.001	0.999	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.001	0.999	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.999	0.001
O81.4 Vacuum extractor delivery	0.000	0.999	0.001
S29.9 Unspecified injury of thorax	0.001	0.999	0.000
D02.0 Larynx	0.001	0.999	0.000
O14.0 Moderate preeclampsia	0.000	0.999	0.001
M25.09 Haemarthrosis (Site unspecified)	0.001	0.999	0.000
M25.08 Haemarthrosis (Other)	0.001	0.999	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.001	0.999	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.001	0.999	0.000
M25.04 Haemarthrosis (Hand)	0.001	0.999	0.000
M25.03 Haemarthrosis (Forearm)	0.001	0.999	0.000
M25.02 Haemarthrosis (Upper arm)	0.001	0.999	0.000
M25.01 Haemarthrosis (Shoulder region)	0.001	0.999	0.000
M25.00 Haemarthrosis (Multiple sites)	0.001	0.999	0.000
O14.2 HELLP syndrome	0.000	0.999	0.001
R20.3 Hyperaesthesia	0.000	0.999	0.001
R20.1 Hypoaesthesia of skin	0.000	0.999	0.001
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.001	0.999	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.001	0.999	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.001	0.999	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.999	0.001
M25.19 Fistula of joint (Site unspecified)	0.001	0.999	0.000
M25.18 Fistula of joint (Other)	0.001	0.999	0.000
M25.17 Fistula of joint (Ankle and foot)	0.001	0.999	0.000
M25.16 Fistula of joint (Lower leg)	0.001	0.999	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.001	0.999	0.000
M25.14 Fistula of joint (Hand)	0.001	0.999	0.000
M25.13 Fistula of joint (Forearm)	0.001	0.999	0.000
M25.12 Fistula of joint (Upper arm)	0.001	0.999	0.000
M25.11 Fistula of joint (Shoulder region)	0.001	0.999	0.000
M25.10 Fistula of joint (Multiple sites)	0.001	0.999	0.000
M25.29 Flail joint (Site unspecified)	0.001	0.999	0.000
M25.28 Flail joint (Other)	0.001	0.999	0.000
M25.27 Flail joint (Ankle and foot)	0.001	0.999	0.000
M25.26 Flail joint (Lower leg)	0.001	0.999	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.001	0.999	0.000
M25.24 Flail joint (Hand)	0.001	0.999	0.000
M25.23 Flail joint (Forearm)	0.001	0.999	0.000
M25.22 Flail joint (Upper arm)	0.001	0.999	0.000
M25.21 Flail joint (Shoulder region)	0.001	0.999	0.000
M25.20 Flail joint (Multiple sites)	0.001	0.999	0.000
K05.2 Acute periodontitis	0.000	0.999	0.001
K05.4 Periodontosis	0.000	0.999	0.001
K05.0 Acute gingivitis	0.000	0.999	0.001
N42.9 Disorder of prostate, unspecified	0.001	0.999	0.000
M25.71 Osteophyte (Shoulder region)	0.001	0.999	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.001	0.999	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.999	0.001
M67.0 Short Achilles tendon (acquired)	0.001	0.999	0.000
S22.4 Multiple fractures of ribs	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations