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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16891315
log Bayes Factor = 91.5417
Chromosome 6   position 26,111,756  (GRCh37) Explore rs16891315 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.999 0.001 0.000
D50-D53 Nutritional anaemias
0.999 0.001 0.000
E05.9 Thyrotoxicosis, unspecified
0.999 0.001 0.000
M06.9 Rheumatoid arthritis, unspecified
0.999 0.001 0.000
M15-M19 Arthrosis
0.999 0.001 0.000
D50 Iron deficiency anaemia
0.999 0.001 0.000
M17 Gonarthrosis [arthrosis of knee]
0.999 0.001 0.000
D50.9 Iron deficiency anaemia, unspecified
0.998 0.002 0.000
Chapter II Neoplasms
0.998 0.002 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.998 0.002 0.000
C43 Malignant melanoma of skin
0.997 0.003 0.000
M17.9 Gonarthrosis, unspecified
0.997 0.003 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.997 0.003 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.997 0.003 0.000
E20-E35 Disorders of other endocrine glands
0.995 0.005 0.000
E16 Other disorders of pancreatic internal secretion
0.995 0.005 0.000
E16.2 Hypoglycaemia, unspecified
0.993 0.007 0.000
M24 Other specific joint derangements
0.992 0.008 0.000
E27 Other disorders of adrenal gland
0.991 0.009 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.987 0.013 0.000
E27.1 Primary adrenocortical insufficiency
0.986 0.014 0.000
M35 Other systemic involvement of connective tissue
0.977 0.023 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.974 0.026 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.974 0.026 0.000
M35.0 Sicca syndrome [Sjogren]
0.971 0.029 0.000
D50.8 Other iron deficiency anaemias
0.970 0.030 0.000
C43.5 Malignant melanoma of trunk
0.966 0.034 0.000
K90 Intestinal malabsorption
0.960 0.039 0.001
M24.1 Other articular cartilage disorders
0.958 0.042 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.958 0.042 0.000
E10.3 With ophthalmic complications
0.957 0.043 0.000
E10.1 With ketoacidosis
0.948 0.052 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.947 0.053 0.000
M23 Internal derangement of knee
0.943 0.057 0.000
M34 Systemic sclerosis
0.941 0.059 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.940 0.060 0.000
M65-M68 Disorders of synovium and tendon
0.939 0.061 0.000
M10 Gout
0.938 0.062 0.000
E14 Unspecified diabetes mellitus
0.932 0.068 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.929 0.071 0.000
M21 Other acquired deformities of limbs
0.921 0.079 0.000
M07 Psoriatic and enteropathic arthropathies
0.917 0.083 0.000
C15-C26 Malignant neoplasms of digestive organs
0.913 0.087 0.000
C43.9 Malignant melanoma of skin, unspecified
0.910 0.090 0.000
C43.4 Malignant melanoma of scalp and neck
0.908 0.092 0.000
C83.3 Large cell (diffuse)
0.908 0.092 0.000
E10.2 With renal complications
0.907 0.093 0.000
M17.0 Primary gonarthrosis, bilateral
0.906 0.094 0.000
E23 Hypofunction and other disorders of pituitary gland
0.904 0.096 0.000
M21.0 Valgus deformity, not elsewhere classified
0.900 0.099 0.000
D80-D89 Certain disorders involving the immune mechanism
0.898 0.102 0.000
E10.5 With peripheral circulatory complications
0.896 0.104 0.000
M00-M03 Infectious arthropathies
0.894 0.106 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.887 0.113 0.000
M11 Other crystal arthropathies
0.886 0.114 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.885 0.115 0.000
M86-M90 Other osteopathies
0.884 0.116 0.000
M17.1 Other primary gonarthrosis
0.884 0.116 0.000
C81 Hodgkin's disease
0.882 0.118 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.882 0.118 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.879 0.121 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.877 0.123 0.000
C85.1 B-cell lymphoma, unspecified
0.871 0.129 0.000
C18 Malignant neoplasm of colon
0.869 0.131 0.000
M60-M63 Disorders of muscles
0.862 0.138 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.860 0.139 0.000
M10.0 Idiopathic gout
0.860 0.140 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.858 0.142 0.000
M07.3 Other psoriatic arthropathies
0.857 0.143 0.000
M65 Synovitis and tenosynovitis
0.855 0.145 0.000
C18.9 Colon, unspecified
0.855 0.145 0.000
C15 Malignant neoplasm of oesophagus
0.853 0.147 0.000
D86 Sarcoidosis
0.851 0.149 0.000
E50-E64 Other nutritional deficiencies
0.850 0.150 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.844 0.156 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.842 0.158 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.162 0.838
K90-K93 Other diseases of the digestive system
0.809 0.163 0.028
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.836 0.164 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.835 0.165 0.000
Chapter I Certain infectious and parasitic diseases
0.835 0.165 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.833 0.167 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.832 0.168 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.831 0.169 0.000
M86 Osteomyelitis
0.830 0.170 0.000
B35-B49 Mycoses
0.829 0.171 0.000
C25 Malignant neoplasm of pancreas
0.829 0.171 0.000
K90.9 Intestinal malabsorption, unspecified
0.826 0.174 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.826 0.174 0.000
Chapter XI Diseases of the digestive system
0.794 0.177 0.028
M34.9 Systemic sclerosis, unspecified
0.821 0.179 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.821 0.179 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.821 0.179 0.000
B37 Candidiasis
0.820 0.180 0.000
M00 Pyogenic arthritis
0.819 0.181 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.818 0.182 0.000
E10.8 With unspecified complications
0.818 0.182 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.815 0.185 0.000
M22 Disorders of patella
0.813 0.187 0.000
M19 Other arthrosis
0.810 0.190 0.000
C82.2 Large cell, follicular
0.809 0.191 0.000
O46.9 Antepartum haemorrhage, unspecified
0.809 0.191 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.191 0.809
E14.1 With ketoacidosis
0.808 0.192 0.000
D86.9 Sarcoidosis, unspecified
0.807 0.193 0.000
E14.5 With peripheral circulatory complications
0.805 0.195 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.805 0.195 0.000
M11.2 Other chondrocalcinosis
0.804 0.196 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.804 0.196 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.803 0.197 0.000
M23.4 Loose body in knee
0.800 0.200 0.000
M14 Arthropathies in other diseases classified elsewhere
0.798 0.202 0.000
M31 Other necrotising vasculopathies
0.797 0.203 0.000
D55-D59 Haemolytic anaemias
0.796 0.204 0.000
M17.3 Other posttraumatic gonarthrosis
0.795 0.205 0.000
B37.0 Candidal stomatitis
0.794 0.206 0.000
C82.0 Small cleaved cell, follicular
0.793 0.207 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.791 0.208 0.000
M70-M79 Other soft tissue disorders
0.791 0.209 0.000
C92 Myeloid leukaemia
0.791 0.209 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.790 0.210 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.789 0.211 0.000
M35.7 Hypermobility syndrome
0.789 0.211 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.788 0.212 0.000
M34.8 Other forms of systemic sclerosis
0.787 0.213 0.000
B37.9 Candidiasis, unspecified
0.787 0.213 0.000
M10.9 Gout, unspecified
0.787 0.213 0.000
M06.4 Inflammatory polyarthropathy
0.785 0.215 0.000
D53 Other nutritional anaemias
0.784 0.216 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.782 0.218 0.000
E23.7 Disorder of pituitary gland, unspecified
0.782 0.218 0.000
M24.0 Loose body in joint
0.781 0.219 0.000
M34.1 CR(E)ST syndrome
0.779 0.221 0.000
M32 Systemic lupus erythematosus
0.779 0.221 0.000
C15.4 Middle third of oesophagus
0.779 0.221 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.778 0.222 0.000
M62 Other disorders of muscle
0.775 0.225 0.000
E14.3 With ophthalmic complications
0.775 0.225 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.772 0.228 0.000
M86.9 Osteomyelitis, unspecified
0.768 0.232 0.000
E27.2 Addisonian crisis
0.767 0.233 0.000
E23.2 Diabetes insipidus
0.765 0.234 0.000
M00.9 Pyogenic arthritis, unspecified
0.765 0.235 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.761 0.239 0.000
C95 Leukaemia of unspecified cell type
0.761 0.239 0.000
E14.6 With other specified complications
0.760 0.240 0.000
M67 Other disorders of synovium and tendon
0.759 0.241 0.000
M72 Fibroblastic disorders
0.758 0.242 0.000
E10.6 With other specified complications
0.757 0.243 0.000
M13 Other arthritis
0.756 0.244 0.000
C83.7 Burkitt's tumour
0.756 0.244 0.000
E22 Hyperfunction of pituitary gland
0.755 0.245 0.000
B02 Zoster [herpes zoster]
0.754 0.246 0.000
E16.1 Other hypoglycaemia
0.754 0.246 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.748 0.251 0.000
M24.7 Protrusio acetabuli
0.746 0.254 0.000
M24.2 Disorder of ligament
0.744 0.256 0.000
C18.4 Transverse colon
0.744 0.256 0.000
O44 Placenta praevia
0.744 0.256 0.000
E24 Cushing's syndrome
0.742 0.258 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.741 0.259 0.000
D52 Folate deficiency anaemia
0.739 0.261 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.739 0.261 0.000
C81.9 Hodgkin's disease, unspecified
0.738 0.262 0.000
M66 Spontaneous rupture of synovium and tendon
0.738 0.262 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.737 0.263 0.000
E10.0 With coma
0.736 0.263 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.736 0.264 0.000
K35-K38 Diseases of appendix
0.726 0.265 0.010
D64.8 Other specified anaemias
0.735 0.265 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.734 0.266 0.000
E20 Hypoparathyroidism
0.734 0.266 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.732 0.268 0.000
M33 Dermatopolymyositis
0.732 0.268 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.731 0.269 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.729 0.271 0.000
M76 Enthesopathies of lower limb, excluding foot
0.728 0.272 0.000
M24.5 Contracture of joint
0.726 0.274 0.000
O43 Placental disorders
0.724 0.276 0.000
M23.49 Loose body in knee-Unspec lig/men
0.724 0.276 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.724 0.276 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.723 0.277 0.000
B44 Aspergillosis
0.721 0.279 0.000
C83.1 Small cleaved cell (diffuse)
0.720 0.280 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.720 0.280 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.719 0.280 0.000
M18 Arthrosis of first carpometacarpal joint
0.719 0.281 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.716 0.283 0.000
M06.2 Rheumatoid bursitis
0.716 0.283 0.000
M06.1 Adult-onset Still's disease
0.716 0.283 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.716 0.284 0.000
D50.1 Sideropenic dysphagia
0.716 0.284 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.716 0.284 0.000
M19.0 Primary arthrosis of other joints
0.716 0.284 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.715 0.285 0.000
C94 Other leukaemias of specified cell type
0.715 0.285 0.000
C93 Monocytic leukaemia
0.715 0.285 0.000
C86 Other specified types of T/NK-cell lymphoma
0.715 0.285 0.000
C43.8 Overlapping malignant melanoma of skin
0.715 0.285 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.715 0.285 0.000
C43.0 Malignant melanoma of lip
0.715 0.285 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
K40 Inguinal hernia
0.003 0.286 0.711
C15.3 Upper third of oesophagus
0.714 0.286 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.714 0.286 0.000
E32 Diseases of thymus
0.714 0.286 0.000
E31 Polyglandular dysfunction
0.714 0.286 0.000
E30 Disorders of puberty, not elsewhere classified
0.714 0.286 0.000
E25 Adrenogenital disorders
0.714 0.286 0.000
E05.8 Other thyrotoxicosis
0.713 0.286 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.713 0.287 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.713 0.287 0.000
E16.4 Abnormal secretion of gastrin
0.713 0.287 0.000
E16.3 Increased secretion of glucagon
0.713 0.287 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.713 0.287 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.712 0.288 0.000
M23.5 Chronic instability of knee
0.712 0.288 0.000
M22.3 Other derangements of patella
0.712 0.288 0.000
M23.9 Internal derangement of knee, unspecified
0.712 0.288 0.000
M24.9 Joint derangement, unspecified
0.711 0.289 0.000
M23.8 Other internal derangements of knee
0.711 0.289 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.710 0.289 0.000
E27.5 Adrenomedullary hyperfunction
0.710 0.290 0.000
E27.0 Other adrenocortical overactivity
0.710 0.290 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.709 0.291 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.709 0.291 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.709 0.291 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.707 0.293 0.000
M15 Polyarthrosis
0.707 0.293 0.000
M17.5 Other secondary gonarthrosis
0.707 0.293 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.706 0.294 0.000
E11 Non-insulin-dependent diabetes mellitus
0.705 0.295 0.000
E13 Other specified diabetes mellitus
0.704 0.296 0.000
D86.3 Sarcoidosis of skin
0.704 0.296 0.000
E34 Other endocrine disorders
0.703 0.297 0.000
C23 Malignant neoplasm of gallbladder
0.702 0.298 0.000
O44.1 Placenta praevia with haemorrhage
0.701 0.299 0.000
M89 Other disorders of bone
0.701 0.299 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.701 0.299 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.701 0.299 0.000
M35.8 Other specified systemic involvement of connective tissue
0.701 0.299 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.701 0.299 0.000
M35.5 Multifocal fibrosclerosis
0.701 0.299 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.701 0.299 0.000
M35.2 Behcet's disease
0.701 0.299 0.000
C15.9 Oesophagus, unspecified
0.700 0.300 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.698 0.302 0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.698 0.302 0.000
C82.6 Cutaneous follicle centre lymphoma
0.698 0.302 0.000
C82.5 Diffuse follicle centre lymphoma
0.698 0.302 0.000
C82.4 Follicular lymphoma grade IIIb
0.698 0.302 0.000
C82.3 Follicular lymphoma grade IIIa
0.698 0.302 0.000
O36 Maternal care for other known or suspected foetal problems
0.698 0.302 0.000
C18.5 Splenic flexure
0.697 0.303 0.000
M23.1 Discoid meniscus (congenital)
0.696 0.304 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.696 0.304 0.000
E03.8 Other specified hypothyroidism
0.695 0.305 0.000
C18.6 Descending colon
0.693 0.307 0.000
E23.6 Other disorders of pituitary gland
0.693 0.307 0.000
Chapter VII Diseases of the eye and adnexa
0.692 0.308 0.000
C25.9 Pancreas, unspecified
0.691 0.309 0.000
K90.3 Pancreatic steatorrhoea
0.688 0.311 0.001
K90.2 Blind loop syndrome, not elsewhere classified
0.688 0.311 0.001
K90.1 Tropical sprue
0.688 0.311 0.001
E70-E90 Metabolic disorders
0.689 0.311 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.689 0.311 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.689 0.311 0.000
K35 Acute appendicitis
0.687 0.312 0.001
M21.7 Unequal limb length (acquired)
0.688 0.312 0.000
M21.6 Other acquired deformities of ankle and foot
0.688 0.312 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.687 0.313 0.000
M24.18 Other articular cartilage disorders (Other)
0.687 0.313 0.000
M24.14 Other articular cartilage disorders (Hand)
0.687 0.313 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.687 0.313 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.687 0.313 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.313 0.687
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.686 0.313 0.000
C85.0 Lymphosarcoma
0.686 0.313 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.686 0.314 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.684 0.316 0.000
B02.9 Zoster without complication
0.683 0.317 0.000
C81.0 Lymphocytic predominance
0.682 0.318 0.000
C92.0 Acute myeloid leukaemia
0.682 0.318 0.000
E14.4 With neurological complications
0.681 0.319 0.000
M24.6 Ankylosis of joint
0.681 0.319 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.680 0.319 0.000
C83.6 Undifferentiated (diffuse)
0.679 0.321 0.000
C83.5 Lymphoblastic (diffuse)
0.679 0.321 0.000
C83.4 Immunoblastic (diffuse)
0.679 0.321 0.000
C83.2 Mixed small and large cell (diffuse)
0.679 0.321 0.000
O46.8 Other antepartum haemorrhage
0.679 0.321 0.000
C81.1 Nodular sclerosis
0.678 0.322 0.000
M23.3 Other meniscus derangements
0.678 0.322 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.677 0.322 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.677 0.323 0.000
M23.0 Cystic meniscus
0.676 0.324 0.000
M65.3 Trigger finger
0.676 0.324 0.000
D84 Other immunodeficiencies
0.676 0.324 0.000
M76.6 Achilles tendinitis
0.676 0.324 0.000
M11.27 Other chondrocalcinosis (Ankle and foot)
0.675 0.325 0.000
K35.9 Acute appendicitis, unspecified
0.675 0.325 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.675 0.325 0.000
M34.0 Progressive systemic sclerosis
0.675 0.325 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.674 0.326 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.674 0.326 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.673 0.326 0.000
D59 Acquired haemolytic anaemia
0.673 0.327 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.673 0.327 0.000
M10.4 Other secondary gout
0.673 0.327 0.000
M10.3 Gout due to impairment of renal function
0.673 0.327 0.000
M10.2 Drug-induced gout
0.673 0.327 0.000
M10.1 Lead-induced gout
0.673 0.327 0.000
E61 Deficiency of other nutrient elements
0.672 0.328 0.000
E53 Deficiency of other B group vitamins
0.671 0.329 0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.671 0.329 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.668 0.332 0.000
E14.8 With unspecified complications
0.668 0.332 0.000
E14.7 With multiple complications
0.668 0.332 0.000
E14.2 Withrenal complications
0.668 0.332 0.000
E14.0 With coma
0.668 0.332 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.667 0.333 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.667 0.333 0.000
K70-K77 Diseases of liver
0.661 0.334 0.005
A15-A19 Tuberculosis
0.666 0.334 0.000
B25-B34 Other viral diseases
0.664 0.336 0.000
E10.4 With neurological complications
0.663 0.337 0.000
C81.2 Mixed cellularity
0.662 0.338 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.662 0.338 0.000
C83.0 Small cell (diffuse)
0.661 0.339 0.000
L40-L45 Papulosquamous disorders
0.661 0.339 0.000
M21.2 Flexion deformity
0.661 0.339 0.000
M62.8 Other specified disorders of muscle
0.661 0.339 0.000
M21.9 Acquired deformity of limb, unspecified
0.660 0.339 0.000
M21.8 Other specified acquired deformities of limbs
0.660 0.339 0.000
M13.0 Polyarthritis, unspecified
0.660 0.340 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.660 0.340 0.000
M10.94 Gout, unspecified (Hand)
0.658 0.342 0.000
C25.3 Pancreatic duct
0.658 0.342 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.658 0.342 0.000
M07.6 Other enteropathic arthropathies
0.657 0.343 0.000
M07.5 Arthropathy in ulcerative colitis
0.657 0.343 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.657 0.343 0.000
M07.2 Psoriatic spondylitis
0.657 0.343 0.000
M07.1 Arthritis mutilans
0.657 0.343 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.657 0.343 0.000
M62.6 Muscle strain
0.657 0.343 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.657 0.343 0.000
C25.2 Tail of pancreas
0.655 0.345 0.000
E55 Vitamin D deficiency
0.654 0.346 0.000
B02.3 Zoster ocular disease
0.653 0.347 0.000
M14.6 Neuropathic arthropathy
0.653 0.347 0.000
L50-L54 Urticaria and erythema
0.653 0.347 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.652 0.347 0.000
M19.8 Other specified arthrosis
0.652 0.348 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.651 0.349 0.000
K36 Other appendicitis
0.647 0.349 0.004
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.651 0.349 0.000
Chapter V Mental and behavioural disorders
0.649 0.351 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.648 0.352 0.000
E23.1 Drug-induced hypopituitarism
0.648 0.352 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.648 0.352 0.000
C84.5 Other and unspecified T-cell lymphomas
0.648 0.352 0.000
M10.90 Gout, unspecified (Multiple sites)
0.647 0.353 0.000
M31.6 Other giant cell arteritis
0.647 0.353 0.000
M86.6 Other chronic osteomyelitis
0.647 0.353 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.646 0.353 0.000
B00 Herpesviral [herpes simplex] infections
0.646 0.354 0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)
0.646 0.354 0.000
M21.08 Valgus deformity, not elsewhere classified (Other)
0.646 0.354 0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)
0.646 0.354 0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)
0.646 0.354 0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)
0.646 0.354 0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)
0.646 0.354 0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)
0.646 0.354 0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)
0.646 0.354 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.644 0.356 0.000
D82 Immunodeficiency associated with other major defects
0.644 0.356 0.000
D81 Combined immunodeficiencies
0.644 0.356 0.000
K90.8 Other intestinal malabsorption
0.642 0.357 0.001
C25.0 Head of pancreas
0.643 0.357 0.000
C88 Malignant immunoproliferative diseases
0.642 0.358 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.641 0.359 0.000
M02 Reactive arthropathies
0.641 0.359 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.641 0.359 0.000
M06.0 Seronegative rheumatoid arthritis
0.641 0.359 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.639 0.361 0.000
M86.8 Other osteomyelitis
0.639 0.361 0.000
M06.3 Rheumatoid nodule
0.639 0.361 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.638 0.362 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.638 0.362 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.637 0.363 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.637 0.363 0.000
D83 Common variable immunodeficiency
0.636 0.364 0.000
M11.9 Crystal arthropathy, unspecified
0.635 0.365 0.000
M11.8 Other specified crystal arthropathies
0.635 0.365 0.000
M11.1 Familial chondrocalcinosis
0.635 0.365 0.000
M11.0 Hydroxyapatite deposition disease
0.635 0.365 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.635 0.365 0.000
O43.8 Other placental disorders
0.634 0.366 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.634 0.366 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.633 0.367 0.000
C81.7 Other Hodgkin's disease
0.632 0.368 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.632 0.368 0.000
C81.3 Lymphocytic depletion
0.632 0.368 0.000
E29 Testicular dysfunction
0.632 0.368 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.632 0.368 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.632 0.368 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.632 0.368 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.632 0.368 0.000
H53-H54 Visual disturbances and blindness
0.632 0.368 0.000
B01 Varicella [chickenpox]
0.631 0.369 0.000
B49 Unspecified mycosis
0.631 0.369 0.000
D53.9 Nutritional anaemia, unspecified
0.630 0.369 0.000
C09 Malignant neoplasm of tonsil
0.630 0.370 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.629 0.370 0.000
M25 Other joint disorders, not elsewhere classified
0.629 0.371 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.628 0.372 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.628 0.372 0.000
M76.67 Achilles tendinitis (Ankle and foot)
0.627 0.373 0.000
M65.8 Other synovitis and tenosynovitis
0.627 0.373 0.000
E40-E46 Malnutrition
0.626 0.373 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.626 0.373 0.000
M24.26 Disorder of ligament (Lower leg)
0.626 0.374 0.000
K75 Other inflammatory liver diseases
0.624 0.375 0.001
B02.2 Zoster with other nervous system involvement
0.625 0.375 0.000
M24.01 Loose body in joint (Shoulder region)
0.624 0.376 0.000
L40 Psoriasis
0.623 0.377 0.000
M19.1 Posttraumatic arthrosis of other joints
0.623 0.377 0.000
B37.3 Candidiasis of vulva and vagina
0.622 0.378 0.000
M21.4 Flat foot [pes planus] (acquired)
0.621 0.379 0.000
M21.1 Varus deformity, not elsewhere classified
0.621 0.379 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.620 0.379 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.620 0.380 0.000
D62 Acute posthaemorrhagic anaemia
0.620 0.380 0.000
L20-L30 Dermatitis and eczema
0.620 0.380 0.000
M00.94 Pyogenic arthritis, unspecified (Hand)
0.619 0.381 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.618 0.382 0.000
M61 Calcification and ossification of muscle
0.618 0.382 0.000
C07 Malignant neoplasm of parotid gland
0.617 0.383 0.000
B44.9 Aspergillosis, unspecified
0.617 0.383 0.000
M10.09 Idiopathic gout (Site unspecified)
0.617 0.383 0.000
M10.08 Idiopathic gout (Other)
0.617 0.383 0.000
M10.06 Idiopathic gout (Lower leg)
0.617 0.383 0.000
M10.05 Idiopathic gout (Pelvic region and thigh)
0.617 0.383 0.000
M10.04 Idiopathic gout (Hand)
0.617 0.383 0.000
M10.03 Idiopathic gout (Forearm)
0.617 0.383 0.000
M10.02 Idiopathic gout (Upper arm)
0.617 0.383 0.000
M10.01 Idiopathic gout (Shoulder region)
0.617 0.383 0.000
M10.00 Idiopathic gout (Multiple sites)
0.617 0.383 0.000
C03 Malignant neoplasm of gum
0.615 0.384 0.000
M24.02 Loose body in joint (Upper arm)
0.615 0.385 0.000
H43-H45 Disorders of vitreous body and globe
0.615 0.385 0.000
H54 Blindness and low vision
0.614 0.386 0.000
M07.38 Other psoriatic arthropathies (Other)
0.614 0.386 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.614 0.386 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.614 0.386 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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