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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16899524
log Bayes Factor = 9.04837
Chromosome 6   position 31,362,310  (GRCh37) Explore rs16899524 on Ensembl!
Variant rs16899524 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.001 0.999
# Top node
0.000 0.002 0.998
L40-L45 Papulosquamous disorders
0.000 0.003 0.997
L40 Psoriasis
0.000 0.004 0.996
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.005 0.995
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.006 0.994
E65-E68 Obesity and other hyperalimentation
0.000 0.008 0.992
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.009 0.991
M06.9 Rheumatoid arthritis, unspecified
0.000 0.012 0.988
L40.5 Arthropathic psoriasis
0.000 0.013 0.987
M06 Other rheumatoid arthritis
0.000 0.013 0.987
E66 Obesity
0.000 0.013 0.987
L40.9 Psoriasis, unspecified
0.000 0.014 0.986
D50-D53 Nutritional anaemias
0.000 0.014 0.986
M05-M14 Inflammatory polyarthropathies
0.000 0.014 0.986
E66.8 Other obesity
0.000 0.015 0.985
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.016 0.984
D50 Iron deficiency anaemia
0.000 0.016 0.984
L57.0 Actinic keratosis
0.000 0.016 0.984
D50.9 Iron deficiency anaemia, unspecified
0.000 0.018 0.982
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.021 0.979
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.026 0.974
Chapter I Certain infectious and parasitic diseases
0.000 0.035 0.965
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.037 0.963
B35-B49 Mycoses
0.000 0.043 0.957
B37 Candidiasis
0.000 0.046 0.954
B37.8 Candidiasis of other sites
0.000 0.048 0.952
Chapter VIII Diseases of the ear and mastoid process
0.000 0.056 0.944
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.056 0.944
E70-E90 Metabolic disorders
0.000 0.057 0.943
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.068 0.932
B25-B34 Other viral diseases
0.000 0.081 0.919
M45-M49 Spondylopathies
0.000 0.084 0.916
L20-L30 Dermatitis and eczema
0.000 0.084 0.916
E06 Thyroiditis
0.000 0.092 0.908
H65-H75 Diseases of middle ear and mastoid
0.000 0.093 0.907
M45 Ankylosing spondylitis
0.000 0.094 0.906
E10-E14 Diabetes mellitus
0.000 0.096 0.904
M07 Psoriatic and enteropathic arthropathies
0.000 0.096 0.904
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.103 0.897
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.103 0.897
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.106 0.894
H72 Perforation of tympanic membrane
0.000 0.107 0.893
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.107 0.892
B37.0 Candidal stomatitis
0.000 0.111 0.889
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.116 0.884
B34 Viral infection of unspecified site
0.000 0.120 0.880
E10 Insulin-dependent diabetes mellitus
0.000 0.120 0.880
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.142 0.858
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.149 0.851
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.150 0.850
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.154 0.846
M07.3 Other psoriatic arthropathies
0.000 0.155 0.845
M35 Other systemic involvement of connective tissue
0.000 0.156 0.844
M35.3 Polymyalgia rheumatica
0.000 0.159 0.841
M20-M25 Other joint disorders
0.000 0.159 0.841
B34.9 Viral infection, unspecified
0.000 0.162 0.838
M05 Seropositive rheumatoid arthritis
0.000 0.165 0.835
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.168 0.832
E06.3 Autoimmune thyroiditis
0.000 0.169 0.831
D68 Other coagulation defects
0.000 0.173 0.827
H80-H83 Diseases of inner ear
0.000 0.173 0.827
Chapter V Mental and behavioural disorders
0.000 0.178 0.822
M95.0 Acquired deformity of nose
0.000 0.178 0.822
L29 Pruritus
0.000 0.181 0.819
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.189 0.811
E89.0 Postprocedural hypothyroidism
0.000 0.193 0.807
E20-E35 Disorders of other endocrine glands
0.000 0.193 0.807
L08 Other local infections of skin and subcutaneous tissue
0.000 0.193 0.807
H65 Nonsuppurative otitis media
0.000 0.194 0.806
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.200 0.800
D80-D89 Certain disorders involving the immune mechanism
0.000 0.202 0.798
E10.9 Without complications
0.000 0.205 0.795
M06.0 Seronegative rheumatoid arthritis
0.000 0.208 0.792
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.208 0.792
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.208 0.792
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.211 0.789
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.213 0.787
B35 Dermatophytosis
0.000 0.223 0.777
L29.0 Pruritus ani
0.000 0.223 0.777
E27 Other disorders of adrenal gland
0.000 0.224 0.776
E10.3 With ophthalmic complications
0.000 0.228 0.772
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.233 0.767
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.233 0.767
E86 Volume depletion
0.000 0.237 0.763
B99-B99 Other infectious diseases
0.000 0.238 0.762
D55-D59 Haemolytic anaemias
0.000 0.241 0.759
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.241 0.759
E27.1 Primary adrenocortical insufficiency
0.000 0.245 0.755
E66.0 Obesity due to excess calories
0.000 0.248 0.752
M00-M03 Infectious arthropathies
0.000 0.250 0.750
E73 Lactose intolerance
0.000 0.256 0.743
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.257 0.743
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.258 0.742
M35.0 Sicca syndrome [Sjogren]
0.000 0.261 0.739
L30 Other dermatitis
0.000 0.261 0.739
H72.0 Central perforation of tympanic membrane
0.000 0.261 0.739
H80 Otosclerosis
0.000 0.265 0.735
E88 Other metabolic disorders
0.000 0.266 0.733
B34.8 Other viral infections of unspecified site
0.000 0.273 0.727
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.273 0.726
E10.1 With ketoacidosis
0.000 0.274 0.726
Chapter XXII Codes for special purposes
0.000 0.275 0.725
D86 Sarcoidosis
0.000 0.276 0.724
L27 Dermatitis due to substances taken internally
0.000 0.276 0.724
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.277 0.723
M34 Systemic sclerosis
0.000 0.280 0.720
D68.5 Primary Thrombophilia
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
L05 Pilonidal cyst
0.000 0.284 0.716
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.284 0.715
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.285 0.715
L44 Other papulosquamous disorders
0.000 0.285 0.715
L41 Parapsoriasis
0.000 0.285 0.715
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.285 0.715
L40.8 Other psoriasis
0.000 0.286 0.714
L40.4 Guttate psoriasis
0.000 0.286 0.714
L40.3 Pustulosis palmaris et plantaris
0.000 0.286 0.714
L40.2 Acrodermatitis continua
0.000 0.286 0.714
L40.1 Generalised pustular psoriasis
0.000 0.286 0.714
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.287 0.713
L58 Radiodermatitis
0.000 0.287 0.713
L55 Sunburn
0.000 0.287 0.713
E14 Unspecified diabetes mellitus
0.000 0.287 0.713
E67 Other hyperalimentation
0.000 0.289 0.711
E68 Sequelae of hyperalimentation
0.000 0.289 0.711
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.289 0.710
L57.5 Actinic granuloma
0.000 0.289 0.710
L57.3 Poikiloderma of Civatte
0.000 0.289 0.710
L57.2 Cutis rhomboidalis nuchae
0.000 0.289 0.710
L57.1 Actinic reticuloid
0.000 0.289 0.710
D68.9 Coagulation defect, unspecified
0.000 0.290 0.710
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.291 0.709
M14 Arthropathies in other diseases classified elsewhere
0.000 0.292 0.708
M06.8 Other specified rheumatoid arthritis
0.000 0.293 0.707
M06.2 Rheumatoid bursitis
0.000 0.293 0.707
M06.1 Adult-onset Still's disease
0.000 0.293 0.707
E66.1 Drug-induced obesity
0.000 0.293 0.707
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.293 0.707
M12 Other specific arthropathies
0.000 0.293 0.707
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.293 0.707
M08 Juvenile arthritis
0.000 0.293 0.707
D50.1 Sideropenic dysphagia
0.000 0.294 0.706
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.300 0.700
E50-E64 Other nutritional deficiencies
0.000 0.302 0.698
H73 Other disorders of tympanic membrane
0.000 0.304 0.696
B25 Cytomegaloviral disease
0.000 0.306 0.694
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.308 0.692
A75-A79 Rickettsioses
0.000 0.308 0.692
A70-A74 Other diseases caused by chlamydiae
0.000 0.308 0.692
A65-A69 Other spirochaetal diseases
0.000 0.308 0.692
A20-A28 Certain zoonotic bacterial diseases
0.000 0.308 0.692
E65 Localised adiposity
0.000 0.309 0.691
L04 Acute lymphadenitis
0.000 0.309 0.691
L01 Impetigo
0.000 0.309 0.691
L00 Staphylococcal scalded skin syndrome
0.000 0.309 0.691
M35.7 Hypermobility syndrome
0.000 0.310 0.690
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.311 0.689
E06.9 Thyroiditis, unspecified
0.000 0.312 0.688
B48 Other mycoses, not elsewhere classified
0.000 0.314 0.686
B47 Mycetoma
0.000 0.314 0.686
B46 Zygomycosis
0.000 0.314 0.686
B45 Cryptococcosis
0.000 0.314 0.686
B43 Chromomycosis and phaeomycotic abscess
0.000 0.314 0.686
B42 Sporotrichosis
0.000 0.314 0.686
B41 Paracoccidioidomycosis
0.000 0.314 0.686
B40 Blastomycosis
0.000 0.314 0.686
B39 Histoplasmosis
0.000 0.314 0.686
B38 Coccidioidomycosis
0.000 0.314 0.686
B36 Other superficial mycoses
0.000 0.314 0.686
E10.2 With renal complications
0.000 0.314 0.686
E74 Other disorders of carbohydrate metabolism
0.000 0.315 0.685
B37.7 Candidal septicaemia
0.000 0.316 0.684
B37.6 Candidal endocarditis
0.000 0.316 0.684
B37.5 Candidal meningitis
0.000 0.316 0.684
E10.5 With peripheral circulatory complications
0.000 0.317 0.683
M46 Other inflammatory spondylopathies
0.000 0.318 0.682
L57.4 Cutis laxa senilis
0.000 0.318 0.681
B24 Unspecified human immunodeficiency virus [HIV] disease
0.000 0.319 0.681
L10-L14 Bullous disorders
0.000 0.323 0.677
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.323 0.676
E84 Cystic fibrosis
0.000 0.324 0.676
E79 Disorders of purine and pyrimidine metabolism
0.000 0.324 0.676
E77 Disorders of glycoprotein metabolism
0.000 0.324 0.676
E76 Disorders of glycosaminoglycan metabolism
0.000 0.324 0.676
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.324 0.676
E72 Other disorders of amino-acid metabolism
0.000 0.324 0.676
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.324 0.676
E70 Disorders of aromatic amino-acid metabolism
0.000 0.324 0.676
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.324 0.676
A15-A19 Tuberculosis
0.000 0.326 0.674
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.328 0.672
F30-F39 Mood [affective] disorders
0.000 0.329 0.671
H65.9 Nonsuppurative otitis media, unspecified
0.000 0.330 0.670
H80.9 Otosclerosis, unspecified
0.000 0.330 0.670
E40-E46 Malnutrition
0.000 0.332 0.668
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.332 0.668
E87.2 Acidosis
0.000 0.334 0.666
L28 Lichen simplex chronicus and prurigo
0.000 0.335 0.665
F40-F48 Neurotic, stress-related and somatoform disorders
0.000 0.336 0.664
B50-B64 Protozoal diseases
0.000 0.336 0.664
H83 Other diseases of inner ear
0.000 0.336 0.664
H60-H62 Diseases of external ear
0.000 0.337 0.663
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.337 0.663
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.338 0.662
M11 Other crystal arthropathies
0.000 0.339 0.661
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.340 0.660
E10.4 With neurological complications
0.000 0.340 0.660
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.340 0.660
E03.8 Other specified hypothyroidism
0.000 0.341 0.659
B33 Other viral diseases, not elsewhere classified
0.000 0.341 0.659
B30 Viral conjunctivitis
0.000 0.341 0.659
B27 Infectious mononucleosis
0.000 0.341 0.659
B26 Mumps
0.000 0.341 0.659
F80-F89 Disorders of psychological development
0.000 0.342 0.658
L24 Irritant contact dermatitis
0.000 0.343 0.657
L21 Seborrhoeic dermatitis
0.000 0.343 0.657
L26 Exfoliative dermatitis
0.000 0.343 0.657
L22 Diaper [napkin] dermatitis
0.000 0.343 0.657
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.346 0.654
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.347 0.653
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.348 0.652
D86.9 Sarcoidosis, unspecified
0.000 0.349 0.651
E06.5 Other chronic thyroiditis
0.000 0.349 0.651
E06.4 Drug-induced thyroiditis
0.000 0.349 0.651
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.349 0.651
E06.1 Subacute thyroiditis
0.000 0.349 0.651
E06.0 Acute thyroiditis
0.000 0.349 0.651
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.349 0.650
H68 Eustachian salpingitis and obstruction
0.000 0.349 0.650
H67 Otitis media in diseases classified elsewhere
0.000 0.349 0.650
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.350 0.650
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.350 0.650
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.350 0.650
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.350 0.650
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.350 0.650
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.350 0.650
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.350 0.650
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.350 0.650
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.350 0.650
H70 Mastoiditis and related conditions
0.000 0.351 0.649
E12 Malnutrition-related diabetes mellitus
0.000 0.351 0.648
L20 Atopic dermatitis
0.000 0.351 0.648
M07.6 Other enteropathic arthropathies
0.000 0.352 0.648
M07.5 Arthropathy in ulcerative colitis
0.000 0.352 0.648
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.352 0.648
M07.2 Psoriatic spondylitis
0.000 0.352 0.648
M07.1 Arthritis mutilans
0.000 0.352 0.648
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.352 0.648
D52 Folate deficiency anaemia
0.000 0.355 0.645
B15-B19 Viral hepatitis
0.000 0.355 0.645
D66 Hereditary factor VIII deficiency
0.000 0.356 0.644
D67 Hereditary factor IX deficiency
0.000 0.357 0.643
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.357 0.643
F60-F69 Disorders of adult personality and behaviour
0.000 0.357 0.643
B37.9 Candidiasis, unspecified
0.000 0.359 0.641
H72.1 Attic perforation of tympanic membrane
0.000 0.360 0.640
M49 Spondylopathies in diseases classified elsewhere
0.000 0.360 0.640
D69 Purpura and other haemorrhagic conditions
0.000 0.360 0.640
M99 Biomechanical lesions, not elsewhere classified
0.000 0.360 0.640
B35.1 Tinea unguium
0.000 0.361 0.639
D51 Vitamin B12 deficiency anaemia
0.000 0.362 0.638
L25 Unspecified contact dermatitis
0.000 0.362 0.638
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.363 0.637
E22 Hyperfunction of pituitary gland
0.000 0.364 0.636
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.364 0.635
M06.3 Rheumatoid nodule
0.000 0.366 0.633
D68.0 Von Willebrand's disease
0.000 0.366 0.633
H65.2 Chronic serous otitis media
0.000 0.367 0.633
B37.4 Candidiasis of other urogenital sites
0.000 0.368 0.632
B34.3 Parvovirus infection, unspecified
0.000 0.369 0.631
B34.2 Coronavirus infection, unspecified
0.000 0.369 0.631
B34.1 Enterovirus infection, unspecified
0.000 0.369 0.631
B34.0 Adenovirus infection, unspecified
0.000 0.369 0.631
E10.0 With coma
0.000 0.369 0.631
E10.7 With multiple complications
0.000 0.369 0.631
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.371 0.629
E85 Amyloidosis
0.000 0.371 0.629
B65-B83 Helminthiases
0.000 0.371 0.628
B37.1 Pulmonary candidiasis
0.000 0.373 0.627
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.373 0.627
E07 Other disorders of thyroid
0.000 0.374 0.626
M91-M94 Chondropathies
0.000 0.374 0.626
E14.9 Without complications
0.000 0.375 0.625
M60-M63 Disorders of muscles
0.000 0.375 0.624
B37.2 Candidiasis of skin and nail
0.000 0.376 0.624
H65.4 Other chronic nonsuppurative otitis media
0.000 0.377 0.623
M06.4 Inflammatory polyarthropathy
0.000 0.378 0.622
L23 Allergic contact dermatitis
0.000 0.379 0.621
D59 Acquired haemolytic anaemia
0.000 0.382 0.618
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.383 0.617
D50.8 Other iron deficiency anaemias
0.000 0.384 0.616
B99 Other and unspecified infectious diseases
0.000 0.384 0.615
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.385 0.615
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.385 0.615
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.385 0.615
E89.5 Postprocedural testicular hypofunction
0.000 0.385 0.615
E89.4 Postprocedural ovarian failure
0.000 0.385 0.615
E89.1 Postprocedural hypoinsulinaemia
0.000 0.385 0.615
D86.0 Sarcoidosis of lung
0.000 0.385 0.615
F31 Bipolar affective disorder
0.000 0.386 0.614
L05.0 Pilonidal cyst with abscess
0.000 0.386 0.613
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.000 0.389 0.610
M95.8 Other specified acquired deformities of musculoskeletal system
0.000 0.389 0.610
M95.5 Acquired deformity of pelvis
0.000 0.389 0.610
M95.4 Acquired deformity of chest and rib
0.000 0.389 0.610
M95.3 Acquired deformity of neck
0.000 0.389 0.610
M95.2 Other acquired deformity of head
0.000 0.389 0.610
M95.1 Cauliflower ear
0.000 0.389 0.610
M30 Polyarteritis nodosa and related conditions
0.000 0.389 0.610
B34.4 Papovirus infection, unspecified
0.000 0.390 0.610
E05.5 Thyroid crisis or storm
0.000 0.390 0.610
E05.4 Thyrotoxicosis factitia
0.000 0.390 0.610
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.390 0.610
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.390 0.610
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.391 0.609
M34.9 Systemic sclerosis, unspecified
0.000 0.391 0.609
E05.9 Thyrotoxicosis, unspecified
0.000 0.392 0.608
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.392 0.608
M07.38 Other psoriatic arthropathies (Other)
0.000 0.394 0.606
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.394 0.606
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.394 0.606
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.394 0.606
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.394 0.606
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.394 0.606
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.394 0.606
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.394 0.606
H65.3 Chronic mucoid otitis media
0.000 0.395 0.605
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.395 0.605
M35.8 Other specified systemic involvement of connective tissue
0.000 0.395 0.605
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.395 0.605
M35.5 Multifocal fibrosclerosis
0.000 0.395 0.605
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.395 0.605
M35.2 Behcet's disease
0.000 0.395 0.605
M35.1 Other overlap syndromes
0.000 0.395 0.605
L30.8 Other specified dermatitis
0.000 0.396 0.604
D68.2 Hereditary deficiency of other clotting factors
0.000 0.396 0.604
E89.3 Postprocedural hypopituitarism
0.000 0.396 0.604
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.397 0.603
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.397 0.603
M32 Systemic lupus erythematosus
0.000 0.397 0.603
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.399 0.601
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.399 0.601
E73.9 Lactose intolerance, unspecified
0.000 0.399 0.601
L29.9 Pruritus, unspecified
0.000 0.399 0.600
E87.7 Fluid overload
0.000 0.401 0.599
M05.8 Other seropositive rheumatoid arthritis
0.000 0.401 0.598
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.401 0.598
M05.2 Rheumatoid vasculitis
0.000 0.401 0.598
M05.1 Rheumatoid lung disease
0.000 0.401 0.598
M05.0 Felty's syndrome
0.000 0.401 0.598
D53 Other nutritional anaemias
0.000 0.401 0.598
M22 Disorders of patella
0.000 0.402 0.598
D68.4 Acquired coagulation factor deficiency
0.000 0.407 0.593
D68.1 Hereditary factor XI deficiency
0.000 0.407 0.593
H82 Vertiginous syndromes in diseases classified elsewhere
0.000 0.407 0.593
E10.8 With unspecified complications
0.000 0.409 0.591
F42 Obsessive-compulsive disorder
0.000 0.410 0.590
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.410 0.590
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.410 0.589
L42 Pityriasis rosea
0.000 0.411 0.589
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.411 0.589
L29.8 Other pruritus
0.000 0.413 0.587
L29.3 Anogenital pruritus, unspecified
0.000 0.413 0.587
L29.1 Pruritus scroti
0.000 0.413 0.587
E89.2 Postprocedural hypoparathyroidism
0.000 0.416 0.583
H69 Other disorders of Eustachian tube
0.000 0.417 0.583
M00 Pyogenic arthritis
0.000 0.418 0.582
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.419 0.581
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.421 0.579
E32 Diseases of thymus
0.000 0.421 0.579
E31 Polyglandular dysfunction
0.000 0.421 0.579
E30 Disorders of puberty, not elsewhere classified
0.000 0.421 0.579
E25 Adrenogenital disorders
0.000 0.421 0.579
E20 Hypoparathyroidism
0.000 0.421 0.579
L08.1 Erythrasma
0.000 0.421 0.578
L08.0 Pyoderma
0.000 0.421 0.578
H65.1 Other acute nonsuppurative otitis media
0.000 0.422 0.578
H65.0 Acute serous otitis media
0.000 0.422 0.578
D60-D64 Aplastic and other anaemias
0.000 0.426 0.574
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions
0.000 0.427 0.573
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases
0.000 0.427 0.573
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms
0.000 0.427 0.573
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
0.000 0.427 0.573
D84 Other immunodeficiencies
0.000 0.428 0.572
D83 Common variable immunodeficiency
0.000 0.428 0.572
D82 Immunodeficiency associated with other major defects
0.000 0.428 0.572
D81 Combined immunodeficiencies
0.000 0.428 0.572
F70-F79 Mental retardation
0.000 0.429 0.571
B35.3 Tinea pedis
0.000 0.429 0.571
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.432 0.568
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.432 0.568
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.432 0.568
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.432 0.568
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.432 0.568
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.432 0.568
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.432 0.568
L40.0 Psoriasis vulgaris
0.000 0.432 0.568
E87.4 Mixed disorder of acid-base balance
0.000 0.432 0.568
E83 Disorders of mineral metabolism
0.000 0.433 0.567
E10.6 With other specified complications
0.000 0.434 0.566
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.437 0.563
L43 Lichen planus
0.000 0.437 0.563
Chapter IX Diseases of the circulatory system
0.000 0.439 0.561
M34.1 CR(E)ST syndrome
0.000 0.439 0.561
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.000 0.439 0.561
M33 Dermatopolymyositis
0.000 0.439 0.561
M31 Other necrotising vasculopathies
0.000 0.439 0.561
D68.6 Other Thrombophilia
0.000 0.440 0.560
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.441 0.559
B37.3 Candidiasis of vulva and vagina
0.000 0.442 0.558
F81 Specific developmental disorders of scholastic skills
0.000 0.442 0.558
F43 Reaction to severe stress, and adjustment disorders
0.000 0.443 0.557
B35.9 Dermatophytosis, unspecified
0.000 0.443 0.557
B35.8 Other dermatophytoses
0.000 0.443 0.557
B35.6 Tinea cruris
0.000 0.443 0.557
B35.5 Tinea imbricata
0.000 0.443 0.557
B35.4 Tinea corporis
0.000 0.443 0.557
B35.2 Tinea manuum
0.000 0.443 0.557
B35.0 Tinea barbae and tinea capitis
0.000 0.443 0.557
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.443 0.557
E27.5 Adrenomedullary hyperfunction
0.000 0.443 0.557
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.443 0.557
E27.2 Addisonian crisis
0.000 0.443 0.557
E27.0 Other adrenocortical overactivity
0.000 0.443 0.557
H72.2 Other marginal perforations of tympanic membrane
0.000 0.444 0.556
E26 Hyperaldosteronism
0.000 0.444 0.555
M80-M85 Disorders of bone density and structure
0.001 0.446 0.553
M10 Gout
0.000 0.449 0.551
L50-L54 Urticaria and erythema
0.000 0.449 0.551
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.449 0.551
A80-A89 Viral infections of the central nervous system
0.000 0.453 0.547
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.453 0.547
H83.0 Labyrinthitis
0.000 0.453 0.547
H72.8 Other perforations of tympanic membrane
0.000 0.454 0.546
M13 Other arthritis
0.000 0.455 0.545
D57 Sickle-cell disorders
0.000 0.455 0.544
D56 Thalassaemia
0.000 0.455 0.544
D55 Anaemia due to enzyme disorders
0.000 0.455 0.544
H73.8 Other specified disorders of tympanic membrane
0.000 0.456 0.544
E13 Other specified diabetes mellitus
0.000 0.457 0.542
L30.9 Dermatitis, unspecified
0.000 0.458 0.542
B49 Unspecified mycosis
0.000 0.458 0.542
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.459 0.541
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.461 0.539
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.000 0.462 0.538
M02 Reactive arthropathies
0.000 0.462 0.538
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.000 0.462 0.538
F42.9 Obsessive-compulsive disorder, unspecified
0.000 0.464 0.536
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.464 0.536
F99-F99 Unspecified mental disorder
0.000 0.466 0.534
E73.8 Other lactose intolerance
0.000 0.467 0.533
E73.1 Secondary lactase deficiency
0.000 0.467 0.533
E73.0 Congenital lactase deficiency
0.000 0.467 0.533
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.467 0.533
L56.4 Polymorphous light eruption
0.000 0.467 0.533
L56.3 Solar urticaria
0.000 0.467 0.533
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.467 0.533
L56.1 Drug photoallergic response
0.000 0.467 0.533
L56.0 Drug phototoxic response
0.000 0.467 0.533
E34 Other endocrine disorders
0.000 0.467 0.533
F30 Manic episode
0.000 0.467 0.533
B25.9 Cytomegaloviral disease, unspecified
0.000 0.468 0.532
A59 Trichomoniasis
0.000 0.468 0.532
A56 Other sexually transmitted chlamydial diseases
0.000 0.468 0.532
A54 Gonococcal infection
0.000 0.468 0.532
A53 Other and unspecified syphilis
0.000 0.468 0.532
A52 Late syphilis
0.000 0.468 0.532
A51 Early syphilis
0.000 0.468 0.532
A50 Congenital syphilis
0.000 0.468 0.532
A64 Unspecified sexually transmitted disease
0.000 0.468 0.532
A58 Granuloma inguinale
0.000 0.468 0.532
A57 Chancroid
0.000 0.468 0.532
A55 Chlamydial lymphogranuloma (venereum)
0.000 0.468 0.532
F20 Schizophrenia
0.000 0.470 0.530
L30.5 Pityriasis alba
0.000 0.470 0.530
L30.4 Erythema intertrigo
0.000 0.470 0.530
L30.3 Infective dermatitis
0.000 0.470 0.530
L30.2 Cutaneous autosensitisation
0.000 0.470 0.530
L30.1 Dyshidrosis [pompholyx]
0.000 0.470 0.530
L30.0 Nummular dermatitis
0.000 0.470 0.530
E53 Deficiency of other B group vitamins
0.000 0.472 0.528
H80.8 Other otosclerosis
0.000 0.473 0.527
H80.2 Cochlear otosclerosis
0.000 0.473 0.527
H80.1 Otosclerosis involving oval window, obliterative
0.000 0.473 0.527
H80.0 Otosclerosis involving oval window, nonobliterative
0.000 0.473 0.527
E88.9 Metabolic disorder, unspecified
0.000 0.474 0.526
E88.8 Other specified metabolic disorders
0.000 0.474 0.526
E88.3 Tumour lysis syndrome
0.000 0.474 0.526

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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