TreeWAS – Variant ID: rs16933006

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.979	0.021
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.019	0.981	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.987	0.013
Z95.8 Presence of other cardiac and vascular implants and grafts	0.012	0.988	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.000	0.989	0.011
K62.6 Ulcer of anus and rectum	0.000	0.989	0.011
H35.3 Degeneration of macula and posterior pole	0.010	0.990	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.000	0.990	0.009
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.000	0.990	0.009
H35 Other retinal disorders	0.010	0.990	0.000
H35.9 Retinal disorder, unspecified	0.009	0.991	0.000
H35.4 Peripheral retinal degeneration	0.009	0.991	0.000
H35.8 Other specified retinal disorders	0.009	0.991	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.992	0.008
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.992	0.008
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.992	0.008
H35.2 Other proliferative retinopathy	0.008	0.992	0.000
H35.0 Background retinopathy and retinal vascular changes	0.008	0.992	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.992	0.008
T43.2 Other and unspecified antidepressants	0.000	0.992	0.008
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.993	0.007
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.993	0.007
H35.1 Retinopathy of prematurity	0.007	0.993	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.993	0.007
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.993	0.007
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.993	0.007
H35.5 Hereditary retinal dystrophy	0.007	0.993	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.993	0.007
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.993	0.007
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.993	0.007
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.993	0.007
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.994	0.006
T43.9 Psychotropic drug, unspecified	0.000	0.994	0.006
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.994	0.006
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.994	0.006
T43.6 Psychostimulants with abuse potential	0.000	0.994	0.006
F10.1 Harmful use	0.000	0.994	0.006
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.994	0.006
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.994	0.006
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.994	0.006
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.994	0.006
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.994	0.006
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.994	0.006
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.994	0.006
T44.0 Anticholinesterase agents	0.000	0.994	0.006
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.994	0.006
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.994	0.006
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.994	0.006
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.994	0.006
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.994	0.006
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.994	0.006
I44.2 Atrioventricular block, complete	0.000	0.994	0.006
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.006	0.994	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.994	0.006
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.994	0.006
T40.2 Other opioids	0.000	0.994	0.006
F20.9 Schizophrenia, unspecified	0.006	0.994	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.994	0.006
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.994	0.006
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.994	0.006
H35.7 Separation of retinal layers	0.005	0.994	0.000
T42.1 Iminostilbenes	0.000	0.994	0.005
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.995	0.005
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.995	0.005
T46.7 Peripheral vasodilators	0.000	0.995	0.005
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.995	0.005
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.995	0.005
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.995	0.005
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.995	0.005
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.995	0.005
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.995	0.005
T47.7 Emetics	0.000	0.995	0.005
T47.6 Antidiarrhoeal drugs	0.000	0.995	0.005
T47.5 Digestants	0.000	0.995	0.005
T47.4 Other laxatives	0.000	0.995	0.005
T47.3 Saline and osmotic laxatives	0.000	0.995	0.005
T47.2 Stimulant laxatives	0.000	0.995	0.005
T47.0 Histamine H(2)-receptor antagonists	0.000	0.995	0.005
T40.4 Other synthetic narcotics	0.000	0.995	0.005
T36 Poisoning by systemic antibiotics	0.000	0.995	0.005
T46.1 Calcium-channel blockers	0.000	0.995	0.005
H35.6 Retinal haemorrhage	0.005	0.995	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.995	0.005
T40.8 Lysergide [LSD]	0.000	0.995	0.005
T40.7 Cannabis (derivatives)	0.000	0.995	0.005
T40.5 Cocaine	0.000	0.995	0.005
T40.3 Methadone	0.000	0.995	0.005
T40.1 Heroin	0.000	0.995	0.005
T40.0 Opium	0.000	0.995	0.005
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.995	0.005
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.995	0.005
T42.3 Barbiturates	0.000	0.995	0.005
T42.2 Succinimides and oxazolidinediones	0.000	0.995	0.005
S82.60 Fracture of lateral malleolus (closed)	0.000	0.995	0.005
T42.0 Hydantoin derivatives	0.000	0.995	0.005
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.995	0.005
T45.5 Anticoagulants	0.000	0.995	0.005
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.995	0.005
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.995	0.005
T39.0 Salicylates	0.000	0.995	0.005
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.995	0.004
T45.8 Other primarily systemic and haematological agents	0.000	0.995	0.004
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.995	0.004
T45.6 Fibrinolysis-affecting drugs	0.000	0.995	0.004
T45.4 Iron and its compounds	0.000	0.995	0.004
T45.3 Enzymes, not elsewhere classified	0.000	0.995	0.004
T45.2 Vitamins, not elsewhere classified	0.000	0.995	0.004
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.995	0.004
T39.4 Antirheumatics, not elsewhere classified	0.000	0.995	0.004
T39.2 Pyrazolone derivatives	0.000	0.995	0.004
T41.5 Therapeutic gases	0.000	0.995	0.004
T41.4 Anaesthetic, unspecified	0.000	0.995	0.004
T41.3 Local anaesthetics	0.000	0.995	0.004
T41.2 Other and unspecified general anaesthetics	0.000	0.995	0.004
T41.1 Intravenous anaesthetics	0.000	0.995	0.004
T41.0 Inhaled anaesthetics	0.000	0.995	0.004
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.995	0.004
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.995	0.004
T48.5 Anti-common-cold drugs	0.000	0.995	0.004
T48.4 Expectorants	0.000	0.995	0.004
T48.3 Antitussives	0.000	0.995	0.004
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.995	0.004
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.995	0.004
T48.0 Oxytocic drugs	0.000	0.995	0.004
T49.9 Topical agent, unspecified	0.000	0.995	0.004
T49.8 Other topical agents	0.000	0.995	0.004
T49.7 Dental drugs, topically applied	0.000	0.995	0.004
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.995	0.004
T49.5 Ophthalmological drugs and preparations	0.000	0.995	0.004
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.995	0.004
T49.3 Emollients, demulcents and protectants	0.000	0.995	0.004
T49.2 Local astringents and local detergents	0.000	0.995	0.004
T49.1 Antipruritics	0.000	0.995	0.004
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.995	0.004
J92.9 Pleural plaque without asbestos	0.005	0.995	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.995	0.004
T42.4 Benzodiazepines	0.000	0.995	0.005
C15.5 Lower third of oesophagus	0.000	0.996	0.004
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.996	0.004
T37.5 Antiviral drugs	0.000	0.996	0.004
T37.4 Anthelminthics	0.000	0.996	0.004
T37.3 Other antiprotozoal drugs	0.000	0.996	0.004
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.996	0.004
T37.1 Antimycobacterial drugs	0.000	0.996	0.004
T37.0 Sulphonamides	0.000	0.996	0.004
T40.6 Other and unspecified narcotics	0.000	0.996	0.004
T38.9 Other and unspecified hormone antagonists	0.000	0.996	0.004
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.996	0.004
T38.7 Androgens and anabolic congeners	0.000	0.996	0.004
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.996	0.004
T38.5 Other oestrogens and progestogens	0.000	0.996	0.004
T38.4 Oral contraceptives	0.000	0.996	0.004
T38.2 Antithyroid drugs	0.000	0.996	0.004
T38.0 Glucocorticoids and synthetic analogues	0.000	0.996	0.004
T45.0 Antiallergic and antiemetic drugs	0.000	0.996	0.004
Z95.4 Presence of other heart-valve replacement	0.004	0.996	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.996	0.004
I77.9 Disorder of arteries and arterioles, unspecified	0.004	0.996	0.000
I44.6 Other and unspecified fascicular block	0.000	0.996	0.004
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.996	0.004
T36.9 Systemic antibiotic, unspecified	0.000	0.996	0.004
T36.8 Other systemic antibiotics	0.000	0.996	0.004
T36.7 Antifungal antibiotics, systemically used	0.000	0.996	0.004
T36.6 Rifamycins	0.000	0.996	0.004
T36.5 Aminoglycosides	0.000	0.996	0.004
T36.4 Tetracyclines	0.000	0.996	0.004
T36.3 Macrolides	0.000	0.996	0.004
T36.2 Chloramphenicol group	0.000	0.996	0.004
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.996	0.004
E29.1 Testicular hypofunction	0.004	0.996	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.996	0.004
J92.0 Pleural plaque with presence of asbestos	0.004	0.996	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.004	0.996	0.000
T50.8 Diagnostic agents	0.000	0.996	0.003
T50.7 Analeptics and opioid receptor antagonists	0.000	0.996	0.003
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.996	0.003
T50.5 Appetite depressants	0.000	0.996	0.003
T50.4 Drugs affecting uric acid metabolism	0.000	0.996	0.003
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.996	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.996	0.003
T50.1 Loop [high-ceiling] diuretics	0.000	0.996	0.003
T50.0 Mineralocorticoids and their antagonists	0.000	0.996	0.003
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.004	0.996	0.000
J92 Pleural plaque	0.003	0.997	0.000
O81.4 Vacuum extractor delivery	0.003	0.997	0.000
M81.98 Osteoporosis, unspecified (Other)	0.003	0.997	0.000
Z95.3 Presence of xenogenic heart valve	0.003	0.997	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.003	0.997	0.000
H33.3 Retinal breaks without detachment	0.000	0.997	0.003
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.003	0.997	0.000
T36.0 Penicillins	0.000	0.997	0.003
K86.1 Other chronic pancreatitis	0.000	0.997	0.003
I44 Atrioventricular and left bundle-branch block	0.000	0.997	0.003
F20 Schizophrenia	0.003	0.997	0.000
K61.0 Anal abscess	0.003	0.997	0.000
Z91.5 Personal history of self-harm	0.000	0.997	0.003
Z95.2 Presence of prosthetic heart valve	0.003	0.997	0.000
K62.3 Rectal prolapse	0.000	0.997	0.003
Z74.0 Reduced mobility	0.000	0.997	0.003
E29 Testicular dysfunction	0.003	0.997	0.000
C16.9 Stomach, unspecified	0.000	0.997	0.003
Y84.0 Cardiac catheterisation	0.003	0.997	0.000
E24 Cushing's syndrome	0.003	0.997	0.000
B25.9 Cytomegaloviral disease, unspecified	0.003	0.997	0.000
T39.1 4-Aminophenol derivatives	0.000	0.997	0.003
E24.9 Cushing's syndrome, unspecified	0.003	0.997	0.000
N80.9 Endometriosis, unspecified	0.000	0.997	0.003
I44.3 Other and unspecified atrioventricular block	0.000	0.997	0.003
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.997	0.003
E24.2 Drug-induced Cushing's syndrome	0.002	0.997	0.000
D47.4 Osteomyelofibrosis	0.002	0.997	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.003	0.997	0.000
I44.1 Atrioventricular block, second degree	0.000	0.997	0.002
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
C15.4 Middle third of oesophagus	0.000	0.998	0.002
I44.5 Left posterior fascicular block	0.000	0.998	0.002
I44.4 Left anterior fascicular block	0.000	0.998	0.002
F20.8 Other schizophrenia	0.002	0.998	0.000
F20.6 Simple schizophrenia	0.002	0.998	0.000
F20.5 Residual schizophrenia	0.002	0.998	0.000
F20.4 Postschizophrenic depression	0.002	0.998	0.000
F20.3 Undifferentiated schizophrenia	0.002	0.998	0.000
F20.2 Catatonic schizophrenia	0.002	0.998	0.000
F20.1 Hebephrenic schizophrenia	0.002	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
E27 Other disorders of adrenal gland	0.002	0.998	0.000
J38.3 Other diseases of vocal cords	0.002	0.998	0.000
K62 Other diseases of anus and rectum	0.000	0.998	0.002
E27.9 Disorder of adrenal gland, unspecified	0.002	0.998	0.000
E27.2 Addisonian crisis	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.002	0.998	0.000
E29.8 Other testicular dysfunction	0.002	0.998	0.000
E29.0 Testicular hyperfunction	0.002	0.998	0.000
S82.6 Fracture of lateral malleolus	0.000	0.998	0.002
F20.0 Paranoid schizophrenia	0.002	0.998	0.000
Z52.3 Bone marrow donor	0.002	0.998	0.000
G90-G99 Other disorders of the nervous system	0.000	0.998	0.002
C15 Malignant neoplasm of oesophagus	0.000	0.998	0.002
K62.9 Disease of anus and rectum, unspecified	0.000	0.998	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.998	0.002
O81 Single delivery by forceps and vacuum extractor	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.998	0.002
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
H65.3 Chronic mucoid otitis media	0.000	0.998	0.002
O81.3 Other and unspecified forceps delivery	0.002	0.998	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
K62.0 Anal polyp	0.000	0.998	0.002
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.002	0.998	0.000
K05.3 Chronic periodontitis	0.002	0.998	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.002	0.998	0.000
R47.0 Dysphasia and aphasia	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.998	0.002
S64.4 Injury of digital nerve of other finger	0.002	0.998	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.002	0.998	0.000
E20-E35 Disorders of other endocrine glands	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.002	0.998	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.002	0.998	0.000
E27.0 Other adrenocortical overactivity	0.002	0.998	0.000
I87.8 Other specified disorders of veins	0.000	0.998	0.002
L30.9 Dermatitis, unspecified	0.000	0.998	0.002
S64.0 Injury of ulnar nerve at wrist and hand level	0.002	0.998	0.000
O21 Excessive vomiting in pregnancy	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.002	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.998	0.002
R39 Other symptoms and signs involving the urinary system	0.002	0.998	0.000
S82.61 Fracture of lateral malleolus (open)	0.000	0.998	0.002
N80.3 Endometriosis of pelvic peritoneum	0.000	0.998	0.002
O75.0 Maternal distress during labour and delivery	0.002	0.998	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.000	0.998	0.002
G91 Hydrocephalus	0.000	0.998	0.002
K11.2 Sialoadenitis	0.000	0.998	0.002
O81.0 Low forceps delivery	0.002	0.998	0.000
R39.0 Extravasation of urine	0.002	0.998	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.000	0.998	0.002
H65 Nonsuppurative otitis media	0.000	0.998	0.002
M79.84 Other specified soft tissue disorders (Hand)	0.002	0.998	0.000
S43.0 Dislocation of shoulder joint	0.000	0.998	0.002
Z74.8 Other problems related to care-provider dependency	0.000	0.998	0.002
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.998	0.002
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
G92 Toxic encephalopathy	0.000	0.998	0.002
C15.8 Overlapping lesion of oesophagus	0.000	0.998	0.002
C15.2 Abdominal part of oesophagus	0.000	0.998	0.002
C15.1 Thoracic part of oesophagus	0.000	0.998	0.002
C15.0 Cervical part of oesophagus	0.000	0.998	0.002
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
G96.0 Cerebrospinal fluid leak	0.000	0.998	0.002
G96 Other disorders of central nervous system	0.000	0.998	0.002
S62.61 Fracture of other finger (open)	0.002	0.998	0.000
C15.3 Upper third of oesophagus	0.000	0.998	0.002
H73.8 Other specified disorders of tympanic membrane	0.000	0.998	0.002
K62.7 Radiation proctitis	0.000	0.998	0.002
O81.5 Delivery by combination of forceps and vacuum extractor	0.002	0.998	0.000
O81.2 Mid-cavity forceps with rotation	0.002	0.998	0.000
O81.1 Mid-cavity forceps delivery	0.002	0.998	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.002	0.998	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
K62.4 Stenosis of anus and rectum	0.000	0.998	0.002
H34 Retinal vascular occlusions	0.002	0.998	0.000
H30-H36 Disorders of choroid and retina	0.002	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.002	0.998	0.000
H31.0 Chorioretinal scars	0.002	0.998	0.000
H61.2 Impacted cerumen	0.000	0.998	0.002
K62.2 Anal prolapse	0.000	0.998	0.002
F10.5 Psychotic disorder	0.000	0.998	0.002
O21.9 Vomiting of pregnancy, unspecified	0.002	0.998	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.002	0.998	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.002	0.998	0.000
M77.57 Other enthesopathy of foot-Ankle/Foot	0.002	0.998	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.000	0.998	0.002
G97.2 Intracranial hypotension following ventricular shunting	0.000	0.998	0.002
O22.4 Haemorrhoids in pregnancy	0.002	0.998	0.000
Z95.0 Presence of cardiac pacemaker	0.002	0.998	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.998	0.002
G91.0 Communicating hydrocephalus	0.000	0.998	0.002
O21.2 Late vomiting of pregnancy	0.002	0.998	0.000
E25 Adrenogenital disorders	0.002	0.998	0.000
E26 Hyperaldosteronism	0.002	0.998	0.000
E20 Hypoparathyroidism	0.002	0.998	0.000
H31 Other disorders of choroid	0.002	0.998	0.000
Z74 Problems related to care-provider dependency	0.000	0.998	0.002
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.998	0.002
K14.8 Other diseases of tongue	0.002	0.998	0.000
M81.9 Osteoporosis, unspecified	0.002	0.998	0.000
K86 Other diseases of pancreas	0.000	0.998	0.002
H34.1 Central retinal artery occlusion	0.002	0.998	0.000
H65.2 Chronic serous otitis media	0.000	0.998	0.002
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.002
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E32 Diseases of thymus	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.002	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.998	0.000
O23 Infections of genito-urinary tract in pregnancy	0.002	0.998	0.000
O21.8 Other vomiting complicating pregnancy	0.002	0.998	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.998	0.002
M79.69 Pain in limb (Site unspecified)	0.002	0.998	0.000
F10.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
K04.7 Periapical abscess without sinus	0.000	0.998	0.002
E23 Hypofunction and other disorders of pituitary gland	0.002	0.998	0.000
S64 Injury of nerves at wrist and hand level	0.002	0.998	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.002	0.998	0.000
H65.0 Acute serous otitis media	0.000	0.998	0.002
R39.2 Extrarenal uraemia	0.002	0.998	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.002	0.998	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.002	0.998	0.000
F10.8 Other mental and behavioural disorders	0.000	0.998	0.002
F10.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
G91.3 Posttraumatic hydrocephalus, unspecified	0.000	0.998	0.002
M77.5 Other enthesopathy of foot	0.002	0.998	0.000
M77.4 Metatarsalgia	0.002	0.998	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.002	0.998	0.000
O90.1 Disruption of perineal obstetric wound	0.002	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.002	0.998	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.998	0.002
F10.6 Amnesic syndrome	0.000	0.998	0.002
H65.1 Other acute nonsuppurative otitis media	0.000	0.998	0.002
S64.3 Injury of digital nerve of thumb	0.002	0.998	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.001	0.998	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.001	0.998	0.000
G96.9 Disorder of central nervous system, unspecified	0.000	0.998	0.001
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.001	0.998	0.000
N80.1 Endometriosis of ovary	0.000	0.998	0.002
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.002	0.998	0.000
O75.9 Complication of labour and delivery, unspecified	0.001	0.998	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.001	0.998	0.000
O75.4 Other complications of obstetric surgery and procedures	0.001	0.998	0.000
O75.3 Other infection during labour	0.001	0.998	0.000
O75.1 Shock during or following labour and delivery	0.001	0.998	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
E20.9 Hypoparathyroidism, unspecified	0.001	0.998	0.000
E23.7 Disorder of pituitary gland, unspecified	0.002	0.998	0.000
H34.0 Transient retinal artery occlusion	0.001	0.998	0.000
M77.1 Lateral epicondylitis	0.002	0.998	0.000
O26.8 Other specified pregnancy-related conditions	0.002	0.998	0.000
R29.6 Tendency to fall, not elsewhere classified	0.000	0.998	0.002
H32 Chorioretinal disorders in diseases classified elsewhere	0.001	0.998	0.000
O90 Complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
L29.9 Pruritus, unspecified	0.000	0.998	0.002
R68.8 Other specified general symptoms and signs	0.000	0.998	0.002
O22 Venous complications in pregnancy	0.002	0.998	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.000	0.998	0.002
D04.7 Skin of lower limb, including hip	0.000	0.998	0.002
E26.0 Primary hyperaldosteronism	0.001	0.998	0.000
G91.8 Other hydrocephalus	0.000	0.998	0.001
M77.9 Enthesopathy, unspecified	0.002	0.998	0.000
O90.9 Complication of the puerperium, unspecified	0.001	0.998	0.000
M77 Other enthesopathies	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.001	0.998	0.000
E20.8 Other hypoparathyroidism	0.001	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.001	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.001	0.998	0.000
E23.0 Hypopituitarism	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.001	0.998	0.000
E25.8 Other adrenogenital disorders	0.001	0.998	0.000
F10.4 Withdrawal state with delirium	0.000	0.998	0.001
G96.8 Other specified disorders of central nervous system	0.000	0.998	0.001
O23.5 Infections of the genital tract in pregnancy	0.001	0.998	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.001	0.998	0.000
O90.0 Disruption of Caesarean section wound	0.001	0.998	0.000
Z52.4 Kidney donor	0.002	0.998	0.000
Z74.3 Need for continuous supervision	0.000	0.998	0.001
G90 Disorders of autonomic nervous system	0.000	0.998	0.001
M81.96 Osteoporosis, unspecified (Lower leg)	0.001	0.998	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.001	0.998	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.001	0.998	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.001	0.998	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.001	0.998	0.000
D68.9 Coagulation defect, unspecified	0.002	0.998	0.000
E26.9 Hyperaldosteronism, unspecified	0.001	0.998	0.000
E26.8 Other hyperaldosteronism	0.001	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.001	0.998	0.000
H31.9 Disorder of choroid, unspecified	0.001	0.998	0.000
H31.4 Choroidal detachment	0.001	0.998	0.000
H31.3 Choroidal haemorrhage and rupture	0.001	0.998	0.000
H31.2 Hereditary choroidal dystrophy	0.001	0.998	0.000
H34.9 Retinal vascular occlusion, unspecified	0.001	0.998	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.001
G95.1 Vascular myelopathies	0.000	0.998	0.001
Z74.2 Need for assistance at home and no other household member able to render care	0.000	0.998	0.001
G95 Other diseases of spinal cord	0.000	0.998	0.001
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.001	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.001	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.001	0.998	0.000
E30.8 Other disorders of puberty	0.001	0.998	0.000
E30.1 Precocious puberty	0.001	0.998	0.000
E30.0 Delayed puberty	0.001	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.001	0.998	0.000
E31.8 Other polyglandular dysfunction	0.001	0.998	0.000
E31.1 Polyglandular hyperfunction	0.001	0.998	0.000
E31.0 Autoimmune polyglandular failure	0.001	0.998	0.000
E32.9 Disease of thymus, unspecified	0.001	0.998	0.000
E32.8 Other diseases of thymus	0.001	0.998	0.000
E32.1 Abscess of thymus	0.001	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.001	0.998	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.001	0.998	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.001	0.998	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.001	0.998	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.000	0.998	0.001
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
H31.1 Choroidal degeneration	0.001	0.998	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.001	0.998	0.000
O23.2 Infections of urethra in pregnancy	0.001	0.998	0.000
O23.1 Infections of bladder in pregnancy	0.001	0.998	0.000
O23.0 Infections of kidney in pregnancy	0.001	0.998	0.000
H30 Chorioretinal inflammation	0.001	0.998	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.002	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.001	0.998	0.000
E23.1 Drug-induced hypopituitarism	0.001	0.998	0.000
G91.2 Normal-pressure hydrocephalus	0.000	0.998	0.001
I44.0 Atrioventricular block, first degree	0.000	0.998	0.001
K07.6 Temporomandibular joint disorders	0.000	0.998	0.001
S64.9 Injury of unspecified nerve at wrist and hand level	0.001	0.998	0.000
S64.8 Injury of other nerves at wrist and hand level	0.001	0.998	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.001	0.998	0.000
E34 Other endocrine disorders	0.001	0.998	0.000
M77.49 Metatarsalgia-Site unspec	0.001	0.999	0.000
M77.48 Metatarsalgia-Other	0.001	0.999	0.000
M77.46 Metatarsalgia-Lower Leg	0.001	0.999	0.000
M77.45 Metatarsalgia-Pelvic/Thigh	0.001	0.999	0.000
M77.44 Metatarsalgia-Hand	0.001	0.999	0.000
M77.43 Metatarsalgia-Forearm	0.001	0.999	0.000
M77.42 Metatarsalgia-Upper arm	0.001	0.999	0.000
M77.41 Metatarsalgia-Shldr region	0.001	0.999	0.000
M77.40 Metatarsalgia-Mult sites	0.001	0.999	0.000
M77.59 Other enthesopathy of foot-Site unspec	0.001	0.999	0.000
M77.58 Other enthesopathy of foot-Other	0.001	0.999	0.000
M77.56 Other enthesopathy of foot-Lower Leg	0.001	0.999	0.000
M77.55 Other enthesopathy of foot-Pelvic/Thigh	0.001	0.999	0.000
M77.54 Other enthesopathy of foot-Hand	0.001	0.999	0.000
M77.53 Other enthesopathy of foot-Forearm	0.001	0.999	0.000
M77.52 Other enthesopathy of foot-Upper arm	0.001	0.999	0.000
M77.51 Other enthesopathy of foot-Shldr region	0.001	0.999	0.000
M77.50 Other enthesopathy of foot-Mult sites	0.001	0.999	0.000
C67.5 Bladder neck	0.001	0.999	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.999	0.001
K61.3 Ischiorectal abscess	0.001	0.999	0.000
K86.8 Other specified diseases of pancreas	0.000	0.999	0.001
M77.3 Calcaneal spur	0.001	0.999	0.000
M79.2 Neuralgia and neuritis, unspecified	0.001	0.999	0.000
Z74.1 Need for assistance with personal care	0.000	0.999	0.001
M13.94 Arthritis, unspecified (Hand)	0.000	0.999	0.001
M81.49 Drug-induced osteoporosis (Site unspecified)	0.001	0.999	0.000
F10.2 Dependence syndrome	0.000	0.999	0.001
G91.1 Obstructive hydrocephalus	0.000	0.999	0.001
K86.2 Cyst of pancreas	0.000	0.999	0.001
M79.8 Other specified soft tissue disorders	0.001	0.999	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.001	0.999	0.000
Q21.1 Atrial septal defect	0.000	0.999	0.001
M79.88 Other specified soft tissue disorders (Other)	0.001	0.999	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations