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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs169679
log Bayes Factor = 52.1935
Chromosome 6   position 28,856,572  (GRCh37) Explore rs169679 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E10.9 Without complications
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.004 0.996
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.005 0.995
E10-E14 Diabetes mellitus
0.000 0.008 0.992
E16.2 Hypoglycaemia, unspecified
0.000 0.009 0.991
E16 Other disorders of pancreatic internal secretion
0.000 0.010 0.990
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.010 0.990
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.010 0.990
E00-E07 Disorders of thyroid gland
0.000 0.012 0.988
E10.2 With renal complications
0.000 0.058 0.942
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.070 0.930
E10.1 With ketoacidosis
0.000 0.075 0.925
E10.4 With neurological complications
0.000 0.125 0.875
E13 Other specified diabetes mellitus
0.000 0.187 0.813
E05.8 Other thyrotoxicosis
0.000 0.192 0.808
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.219 0.781
E10.7 With multiple complications
0.000 0.252 0.748
E16.1 Other hypoglycaemia
0.000 0.256 0.744
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.730 0.270 0.000
E10.0 With coma
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.287 0.713
E05.4 Thyrotoxicosis factitia
0.000 0.287 0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.287 0.713
E12 Malnutrition-related diabetes mellitus
0.000 0.288 0.711
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.290 0.710
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.290 0.710
E16.4 Abnormal secretion of gastrin
0.000 0.290 0.710
E16.3 Increased secretion of glucagon
0.000 0.290 0.710
E15 Nondiabetic hypoglycaemic coma
0.000 0.290 0.710
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.292 0.708
E00 Congenital iodine-deficiency syndrome
0.000 0.292 0.708
E13.9 Without complications
0.000 0.317 0.683
E10.5 With peripheral circulatory complications
0.000 0.332 0.667
E10.6 With other specified complications
0.000 0.335 0.664
E40-E46 Malnutrition
0.000 0.341 0.659
E14 Unspecified diabetes mellitus
0.000 0.349 0.651
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.366 0.634
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.399 0.600
E06 Thyroiditis
0.000 0.400 0.600
E13.3 With ophthalmic complications
0.000 0.414 0.586
E13.8 With unspecified complications
0.000 0.417 0.583
E13.7 With multiple complications
0.000 0.417 0.583
E13.6 With other specified complications
0.000 0.417 0.583
E13.5 With peripheral circulatory complications
0.000 0.417 0.583
E13.4 With neurological complications
0.000 0.417 0.583
E13.2 With renal complications
0.000 0.417 0.583
E13.1 With ketoacidosis
0.000 0.417 0.583
E13.0 With coma
0.000 0.417 0.583
E07 Other disorders of thyroid
0.000 0.432 0.568
E10.8 With unspecified complications
0.000 0.467 0.533
E14.3 With ophthalmic complications
0.000 0.469 0.531
E14.1 With ketoacidosis
0.000 0.476 0.524
E12.9 Without complications
0.000 0.490 0.510
E12.8 With unspecified complications
0.000 0.490 0.510
E12.7 With multiple complications
0.000 0.490 0.510
E12.6 With other specified complications
0.000 0.490 0.510
E12.5 With peripheral circulatory complications
0.000 0.490 0.510
E12.4 With neurological complications
0.000 0.490 0.510
E12.3 With ophthalmic complications
0.000 0.490 0.510
E12.2 With renal complications
0.000 0.490 0.510
E12.1 With ketoacidosis
0.000 0.490 0.510
E12.0 With coma
0.000 0.490 0.510
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.492 0.508
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.492 0.508
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.492 0.508
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.492 0.508
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.492 0.508
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.492 0.508
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.492 0.508
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.492 0.508
E14.6 With other specified complications
0.000 0.506 0.494
E06.9 Thyroiditis, unspecified
0.000 0.517 0.483
E14.4 With neurological complications
0.000 0.517 0.483
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.527 0.473
E45 Retarded development following protein-energy malnutrition
0.000 0.527 0.473
E43 Unspecified severe protein-energy malnutrition
0.000 0.527 0.473
E42 Marasmic kwashiorkor
0.000 0.527 0.473
E41 Nutritional marasmus
0.000 0.527 0.473
E40 Kwashiorkor
0.000 0.527 0.473
E14.8 With unspecified complications
0.000 0.529 0.471
E14.7 With multiple complications
0.000 0.533 0.467
E03 Other hypothyroidism
0.000 0.549 0.451
E06.1 Subacute thyroiditis
0.000 0.550 0.450
E07.8 Other specified disorders of thyroid
0.000 0.553 0.447
E14.2 Withrenal complications
0.000 0.556 0.444
E14.5 With peripheral circulatory complications
0.000 0.560 0.439
K90 Intestinal malabsorption
0.000 0.562 0.438
E14.0 With coma
0.000 0.563 0.437
E06.4 Drug-induced thyroiditis
0.000 0.569 0.430
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.569 0.430
E06.0 Acute thyroiditis
0.000 0.569 0.430
E46 Unspecified protein-energy malnutrition
0.000 0.578 0.422
E06.5 Other chronic thyroiditis
0.000 0.588 0.412
E07.1 Dyshormogenetic goitre
0.000 0.592 0.408
E07.0 Hypersecretion of calcitonin
0.000 0.592 0.408
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.625 0.374
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.630 0.370
E50-E64 Other nutritional deficiencies
0.000 0.657 0.343
E44.1 Mild protein-energy malnutrition
0.000 0.661 0.339
E44.0 Moderate protein-energy malnutrition
0.000 0.661 0.339
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.663 0.337
E03.5 Myxoedema coma
0.000 0.676 0.324
E03.4 Atrophy of thyroid (acquired)
0.000 0.676 0.324
E03.3 Postinfectious hypothyroidism
0.000 0.676 0.324
E65-E68 Obesity and other hyperalimentation
0.000 0.677 0.323
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.677 0.323
K90.3 Pancreatic steatorrhoea
0.000 0.686 0.314
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.686 0.314
K90.1 Tropical sprue
0.000 0.686 0.314
K90.8 Other intestinal malabsorption
0.000 0.688 0.312
E03.1 Congenital hypothyroidism without goitre
0.000 0.689 0.311
E03.8 Other specified hypothyroidism
0.000 0.729 0.271
E11 Non-insulin-dependent diabetes mellitus
0.000 0.750 0.250
E54 Ascorbic acid deficiency
0.000 0.750 0.250
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.754 0.246
E63 Other nutritional deficiencies
0.000 0.754 0.246
E50 Vitamin A deficiency
0.000 0.754 0.246
E60 Dietary zinc deficiency
0.000 0.754 0.246
E59 Dietary selenium deficiency
0.000 0.754 0.246
E52 Niacin deficiency [pellagra]
0.000 0.754 0.246
E51 Thiamine deficiency
0.000 0.756 0.244
E56 Other vitamin deficiencies
0.000 0.768 0.232
E67 Other hyperalimentation
0.000 0.768 0.232
E68 Sequelae of hyperalimentation
0.000 0.768 0.232
E55 Vitamin D deficiency
0.000 0.772 0.227
E11.6 With other specified complications
0.000 0.773 0.227
E58 Dietary calcium deficiency
0.000 0.776 0.224
K90.9 Intestinal malabsorption, unspecified
0.000 0.781 0.219
E11.1 With ketoacidosis
0.000 0.782 0.218
E11.0 With coma
0.000 0.794 0.206
E83 Disorders of mineral metabolism
0.171 0.807 0.022
E61 Deficiency of other nutrient elements
0.000 0.810 0.190
E06.3 Autoimmune thyroiditis
0.000 0.810 0.189
E11.2 With renal complications
0.000 0.817 0.182
M45.X9 Ankylosing spondylitis (Site unspecified)
0.180 0.820 0.000
E11.7 With multiple complications
0.000 0.820 0.180
E14.9 Without complications
0.000 0.822 0.178
E03.9 Hypothyroidism, unspecified
0.000 0.822 0.178
E50.9 Vitamin A deficiency, unspecified
0.000 0.823 0.177
E50.8 Other manifestations of vitamin A deficiency
0.000 0.823 0.177
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.823 0.177
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.823 0.177
E50.5 Vitamin A deficiency with night blindness
0.000 0.823 0.177
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.823 0.177
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.823 0.177
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.823 0.177
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.823 0.177
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.823 0.177
E63.9 Nutritional deficiency, unspecified
0.000 0.823 0.177
E63.8 Other specified nutritional deficiencies
0.000 0.823 0.177
E63.1 Imbalance of constituents of food intake
0.000 0.823 0.177
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.823 0.177
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.823 0.177
E64.8 Sequelae of other nutritional deficiencies
0.000 0.823 0.177
E64.3 Sequelae of rickets
0.000 0.823 0.177
E64.2 Sequelae of vitamin C deficiency
0.000 0.823 0.177
E64.1 Sequelae of vitamin A deficiency
0.000 0.823 0.177
E64.0 Sequelae of protein-energy malnutrition
0.000 0.823 0.177
E51.9 Thiamine deficiency, unspecified
0.000 0.825 0.175
E51.8 Other manifestations of thiamine deficiency
0.000 0.825 0.175
E51.1 Beriberi
0.000 0.825 0.175
E51.2 Wernicke's encephalopathy
0.000 0.827 0.173
E07.9 Disorder of thyroid, unspecified
0.000 0.829 0.171
E65 Localised adiposity
0.000 0.829 0.170
E56.9 Vitamin deficiency, unspecified
0.000 0.833 0.166
E56.8 Deficiency of other vitamins
0.000 0.833 0.166
E56.0 Deficiency of vitamin E
0.000 0.833 0.166
E67.8 Other specified hyperalimentation
0.000 0.833 0.166
E67.3 Hypervitaminosis D
0.000 0.833 0.166
E67.2 Megavitamin-B6 syndrome
0.000 0.833 0.166
E67.1 Hypercarotenaemia
0.000 0.833 0.166
E67.0 Hypervitaminosis A
0.000 0.833 0.166
E53 Deficiency of other B group vitamins
0.000 0.835 0.165
E55.0 Rickets, active
0.000 0.837 0.163
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.847 0.153
E56.1 Deficiency of vitamin K
0.000 0.848 0.152
E83.3 Disorders of phosphorus metabolism
0.146 0.848 0.005
E55.9 Vitamin D deficiency, unspecified
0.000 0.855 0.144
I83 Varicose veins of lower extremities
0.140 0.860 0.000
E83.8 Other disorders of mineral metabolism
0.123 0.861 0.016
E83.2 Disorders of zinc metabolism
0.123 0.861 0.016
E83.0 Disorders of copper metabolism
0.123 0.861 0.016
E83.9 Disorder of mineral metabolism, unspecified
0.123 0.862 0.016
E61.9 Deficiency of nutrient element, unspecified
0.000 0.863 0.136
E61.8 Deficiency of other specified nutrient elements
0.000 0.863 0.136
E61.7 Deficiency of multiple nutrient elements
0.000 0.863 0.136
E61.6 Vanadium deficiency
0.000 0.863 0.136
E61.5 Molybdenum deficiency
0.000 0.863 0.136
E61.4 Chromium deficiency
0.000 0.863 0.136
E61.3 Manganese deficiency
0.000 0.863 0.136
E61.0 Copper deficiency
0.000 0.863 0.136
E11.8 With unspecified complications
0.000 0.868 0.132
E53.9 Vitamin B deficiency, unspecified
0.000 0.879 0.121
E61.2 Magnesium deficiency
0.000 0.880 0.119
E53.1 Pyridoxine deficiency
0.000 0.881 0.118
E53.0 Riboflavin deficiency
0.000 0.881 0.118
E70-E90 Metabolic disorders
0.002 0.885 0.113
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.891 0.109
E11.5 With peripheral circulatory complications
0.000 0.892 0.108
E61.1 Iron deficiency
0.000 0.894 0.106
E20-E35 Disorders of other endocrine glands
0.000 0.894 0.106
E78.2 Mixed hyperlipidaemia
0.000 0.894 0.106
E24 Cushing's syndrome
0.000 0.903 0.097
E78.1 Pure hyperglyceridaemia
0.000 0.905 0.095
I83.0 Varicose veins of lower extremities with ulcer
0.094 0.906 0.000
M45 Ankylosing spondylitis
0.093 0.907 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.907 0.093
E88 Other metabolic disorders
0.001 0.909 0.090
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.910 0.088
E74 Other disorders of carbohydrate metabolism
0.001 0.912 0.086
E78.6 Lipoprotein deficiency
0.000 0.913 0.087
E73 Lactose intolerance
0.001 0.914 0.084
E24.9 Cushing's syndrome, unspecified
0.000 0.916 0.084
E84 Cystic fibrosis
0.001 0.917 0.082
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.917 0.083
E77 Disorders of glycoprotein metabolism
0.002 0.917 0.081
E76 Disorders of glycosaminoglycan metabolism
0.002 0.917 0.081
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.002 0.917 0.081
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.002 0.917 0.081
E78.3 Hyperchylomicronaemia
0.000 0.918 0.082
E85 Amyloidosis
0.001 0.919 0.079
E24.0 Pituitary-dependent Cushing's disease
0.000 0.920 0.080
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.079 0.920 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.921 0.079
E88.9 Metabolic disorder, unspecified
0.000 0.921 0.078
E70 Disorders of aromatic amino-acid metabolism
0.002 0.922 0.077
R31 Unspecified haematuria
0.078 0.922 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.923 0.077
E79 Disorders of purine and pyrimidine metabolism
0.002 0.923 0.075
E28 Ovarian dysfunction
0.000 0.923 0.077
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.924 0.076
E32 Diseases of thymus
0.000 0.924 0.076
E30 Disorders of puberty, not elsewhere classified
0.000 0.924 0.076
E25 Adrenogenital disorders
0.000 0.924 0.076
E72 Other disorders of amino-acid metabolism
0.002 0.925 0.074
M45.X2 Ankylosing spondylitis (Cervical region)
0.074 0.926 0.000
E20 Hypoparathyroidism
0.000 0.926 0.074
E24.2 Drug-induced Cushing's syndrome
0.000 0.927 0.073
E31 Polyglandular dysfunction
0.000 0.927 0.073
C15 Malignant neoplasm of oesophagus
0.000 0.928 0.072
E88.2 Lipomatosis, not elsewhere classified
0.000 0.929 0.071
E75.5 Other lipid storage disorders
0.001 0.929 0.070
C15-C26 Malignant neoplasms of digestive organs
0.000 0.930 0.070
M45.X6 Ankylosing spondylitis (Lumbar region)
0.070 0.930 0.000
E24.8 Other Cushing's syndrome
0.000 0.930 0.070
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.930 0.070
E24.3 Ectopic ACTH syndrome
0.000 0.930 0.070
E24.1 Nelson's syndrome
0.000 0.930 0.070
E83.4 Disorders of magnesium metabolism
0.060 0.930 0.010
C20 Malignant neoplasm of rectum
0.000 0.930 0.070
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.931 0.069
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.931 0.069
E78.4 Other hyperlipidaemia
0.000 0.931 0.069
C15.5 Lower third of oesophagus
0.000 0.933 0.067
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.067 0.933 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.067 0.933 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.067 0.933 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.067 0.933 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.067 0.933 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.067 0.933 0.000
C15.4 Middle third of oesophagus
0.000 0.934 0.066
E85.4 Organ-limited amyloidosis
0.001 0.934 0.065
E75.2 Other sphingolipidosis
0.001 0.935 0.064
E73.9 Lactose intolerance, unspecified
0.001 0.935 0.064
E75.6 Lipid storage disorder, unspecified
0.001 0.935 0.064
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.935 0.064
E75.3 Sphingolipidosis, unspecified
0.001 0.935 0.064
E75.1 Other gangliosidosis
0.001 0.935 0.064
E75.0 GM2 gangliosidosis
0.001 0.935 0.064
E29 Testicular dysfunction
0.000 0.936 0.064
E11.3 With ophthalmic complications
0.000 0.936 0.064
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.937 0.062
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.937 0.062
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.937 0.062
E74.2 Disorders of galactose metabolism
0.001 0.937 0.062
E74.1 Disorders of fructose metabolism
0.001 0.937 0.062
E73.8 Other lactose intolerance
0.001 0.938 0.061
E73.1 Secondary lactase deficiency
0.001 0.938 0.061
E73.0 Congenital lactase deficiency
0.001 0.938 0.061
E88.8 Other specified metabolic disorders
0.001 0.939 0.061
E74.0 Glycogen storage disease
0.001 0.939 0.060
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.939 0.060
E85.3 Secondary systemic amyloidosis
0.001 0.940 0.060
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.940 0.060
C15.9 Oesophagus, unspecified
0.000 0.940 0.060
E84.8 Cystic fibrosis with other manifestations
0.001 0.940 0.059
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.940 0.059
E21.4 Other specified disorders of parathyroid gland
0.000 0.940 0.060
E21.2 Other hyperparathyroidism
0.000 0.940 0.060
E71.3 Disorders of fatty-acid metabolism
0.001 0.940 0.058
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.940 0.058
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.940 0.058
E71.0 Maple-syrup-urine disease
0.001 0.940 0.058
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.940 0.058
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.940 0.058
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.940 0.058
E76.2 Other mucopolysaccharidoses
0.001 0.940 0.058
E76.1 Mucopolysaccharidosis, type II
0.001 0.940 0.058
E76.0 Mucopolysaccharidosis, type I
0.001 0.940 0.058
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.940 0.058
E77.8 Other disorders of glycoprotein metabolism
0.001 0.940 0.058
E77.1 Defects in glycoprotein degradation
0.001 0.940 0.058
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.940 0.058
E84.9 Cystic fibrosis, unspecified
0.001 0.941 0.058
E28.2 Polycystic ovarian syndrome
0.000 0.941 0.059
I83.1 Varicose veins of lower extremities with inflammation
0.059 0.941 0.000
E85.8 Other amyloidosis
0.001 0.942 0.057
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.942 0.057
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.942 0.057
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.942 0.057
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.942 0.058
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.943 0.055
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.943 0.055
E70.2 Disorders of tyrosine metabolism
0.001 0.943 0.055
E70.1 Other hyperphenylalaninaemias
0.001 0.943 0.055
E70.0 Classical phenylketonuria
0.001 0.943 0.055
E11.4 With neurological complications
0.000 0.944 0.056
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.056 0.944 0.000
C15.0 Cervical part of oesophagus
0.000 0.944 0.056
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.944 0.054
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.944 0.054
E79.1 Lesch-Nyhan syndrome
0.001 0.944 0.054
E28.9 Ovarian dysfunction, unspecified
0.000 0.945 0.055
E28.8 Other ovarian dysfunction
0.000 0.945 0.055
E28.1 Androgen excess
0.000 0.945 0.055
E28.0 Oestrogen excess
0.000 0.945 0.055
E30.9 Disorder of puberty, unspecified
0.000 0.945 0.055
E30.8 Other disorders of puberty
0.000 0.945 0.055
E30.1 Precocious puberty
0.000 0.945 0.055
E30.0 Delayed puberty
0.000 0.945 0.055
E32.9 Disease of thymus, unspecified
0.000 0.945 0.055
E32.8 Other diseases of thymus
0.000 0.945 0.055
E32.1 Abscess of thymus
0.000 0.945 0.055
E32.0 Persistent hyperplasia of thymus
0.000 0.945 0.055
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.945 0.055
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.945 0.055
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.945 0.055
E25.9 Adrenogenital disorder, unspecified
0.000 0.945 0.054
E25.8 Other adrenogenital disorders
0.000 0.945 0.054
C15.3 Upper third of oesophagus
0.000 0.946 0.054
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.946 0.053
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.946 0.053
E72.5 Disorders of glycine metabolism
0.001 0.946 0.053
E72.4 Disorders of ornithine metabolism
0.001 0.946 0.053
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.946 0.053
E72.2 Disorders of urea cycle metabolism
0.001 0.946 0.053
E34 Other endocrine disorders
0.000 0.946 0.054
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.946 0.054
E88.3 Tumour lysis syndrome
0.001 0.946 0.053
E20.9 Hypoparathyroidism, unspecified
0.000 0.946 0.054
E20.1 Pseudohypoparathyroidism
0.000 0.947 0.053
E20.0 Idiopathic hypoparathyroidism
0.000 0.947 0.053
C15.1 Thoracic part of oesophagus
0.000 0.947 0.053
E72.0 Disorders of amino-acid transport
0.001 0.947 0.051
E31.9 Polyglandular dysfunction, unspecified
0.000 0.948 0.052
E31.8 Other polyglandular dysfunction
0.000 0.948 0.052
E31.1 Polyglandular hyperfunction
0.000 0.948 0.052
E70.3 Albinism
0.001 0.948 0.051
C15.8 Overlapping lesion of oesophagus
0.000 0.948 0.052
C15.2 Abdominal part of oesophagus
0.000 0.948 0.052
E28.3 Primary ovarian failure
0.000 0.948 0.052
E78.8 Other disorders of lipoprotein metabolism
0.000 0.949 0.051
C25 Malignant neoplasm of pancreas
0.000 0.949 0.051
E26 Hyperaldosteronism
0.000 0.949 0.050
E20.8 Other hypoparathyroidism
0.000 0.950 0.050
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.950 0.049
C17 Malignant neoplasm of small intestine
0.000 0.951 0.049
E31.0 Autoimmune polyglandular failure
0.000 0.951 0.049
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.951 0.047
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.951 0.048
C17.0 Duodenum
0.000 0.954 0.046
E29.8 Other testicular dysfunction
0.000 0.954 0.046
E29.0 Testicular hyperfunction
0.000 0.954 0.046
E29.9 Testicular dysfunction, unspecified
0.000 0.955 0.045
C21 Malignant neoplasm of anus and anal canal
0.000 0.955 0.045
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.955 0.043
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.956 0.044
E21.0 Primary hyperparathyroidism
0.000 0.956 0.044
E04 Other non-toxic goitre
0.002 0.956 0.042
C25.3 Pancreatic duct
0.000 0.957 0.043
C25.2 Tail of pancreas
0.000 0.958 0.042
C25.1 Body of pancreas
0.000 0.960 0.040
E23 Hypofunction and other disorders of pituitary gland
0.000 0.960 0.040
C25.8 Overlapping lesion of pancreas
0.000 0.960 0.040
C25.4 Endocrine pancreas
0.000 0.960 0.040
E34.3 Short stature, not elsewhere classified
0.000 0.961 0.039
E34.5 Androgen resistance syndrome
0.000 0.961 0.039
E34.4 Constitutional tall stature
0.000 0.961 0.039
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.961 0.039
E34.1 Other hypersecretion of intestinal hormones
0.000 0.961 0.039
I77 Other disorders of arteries and arterioles
0.000 0.961 0.039
E22 Hyperfunction of pituitary gland
0.000 0.961 0.039
E85.9 Amyloidosis, unspecified
0.001 0.961 0.037
I77.6 Arteritis, unspecified
0.000 0.962 0.038
I73.9 Peripheral vascular disease, unspecified
0.000 0.963 0.037
C24.0 Extrahepatic bile duct
0.000 0.963 0.037
I73 Other peripheral vascular diseases
0.000 0.963 0.037
E66 Obesity
0.000 0.963 0.037
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.963 0.037
E26.8 Other hyperaldosteronism
0.000 0.963 0.036
E26.1 Secondary hyperaldosteronism
0.000 0.963 0.036
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.964 0.036
E29.1 Testicular hypofunction
0.000 0.964 0.035
C17.8 Overlapping lesion of small intestine
0.000 0.965 0.035
C17.3 Meckel's diverticulum
0.000 0.965 0.035
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.965 0.035
E34.9 Endocrine disorder, unspecified
0.000 0.965 0.035
E23.7 Disorder of pituitary gland, unspecified
0.000 0.965 0.035
E34.8 Other specified endocrine disorders
0.000 0.965 0.034
I77.8 Other specified disorders of arteries and arterioles
0.000 0.966 0.034
C25.7 Other parts of pancreas
0.000 0.966 0.033
E80.2 Other porphyria
0.001 0.967 0.032
C21.2 Cloacogenic zone
0.000 0.968 0.032
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.968 0.031
E80.5 Crigler-Najjar syndrome
0.001 0.968 0.031
E80.3 Defects of catalase and peroxydase
0.001 0.968 0.031
E80.0 Hereditary erythropoietic porphyria
0.001 0.968 0.031
E26.9 Hyperaldosteronism, unspecified
0.001 0.968 0.032
I73.0 Raynaud's syndrome
0.000 0.968 0.032
C24.8 Overlapping lesion of biliary tract
0.000 0.968 0.032
E04.8 Other specified non-toxic goitre
0.002 0.968 0.030
C17.1 Jejunum
0.000 0.969 0.031
I74 Arterial embolism and thrombosis
0.000 0.969 0.031
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.969 0.031
E53.8 Deficiency of other specified B group vitamins
0.000 0.969 0.031
I72 Other aneurysm
0.000 0.969 0.031
C23 Malignant neoplasm of gallbladder
0.000 0.969 0.030
E34.0 Carcinoid syndrome
0.000 0.970 0.030
E80.6 Other disorders of bilirubin metabolism
0.001 0.970 0.029
C24.9 Biliary tract, unspecified
0.000 0.970 0.030
I77.2 Rupture of artery
0.000 0.971 0.029
I77.1 Stricture of artery
0.000 0.971 0.029
I74.5 Embolism and thrombosis of iliac artery
0.000 0.971 0.029
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.971 0.029
E23.1 Drug-induced hypopituitarism
0.000 0.971 0.029
C25.9 Pancreas, unspecified
0.000 0.971 0.029
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.971 0.029
I77.3 Arterial fibromuscular dysplasia
0.000 0.971 0.028
I73.8 Other specified peripheral vascular diseases
0.000 0.972 0.028
I77.5 Necrosis of artery
0.000 0.972 0.028
I77.4 Coeliac artery compression syndrome
0.000 0.972 0.028
E22.8 Other hyperfunction of pituitary gland
0.000 0.972 0.028
I70 Atherosclerosis
0.000 0.972 0.028
C21.0 Anus, unspecified
0.000 0.973 0.027
K90-K93 Other diseases of the digestive system
0.000 0.973 0.027
Z72.0 Tobacco use
0.027 0.973 0.000
E80.1 Porphyria cutanea tarda
0.001 0.973 0.026
C21.1 Anal canal
0.000 0.973 0.027
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.973 0.027
E66.1 Drug-induced obesity
0.000 0.973 0.027
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.973 0.027
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.973 0.027
I72.4 Aneurysm of artery of lower extremity
0.000 0.974 0.026
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.974 0.026
M45-M49 Spondylopathies
0.026 0.974 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.974 0.026
I72.3 Aneurysm of iliac artery
0.000 0.975 0.025
E22.1 Hyperprolactinaemia
0.000 0.975 0.025
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.975 0.025
I72.0 Aneurysm of carotid artery
0.000 0.975 0.025
E78.0 Pure hypercholesterolaemia
0.000 0.975 0.025
C17.2 Ileum
0.000 0.976 0.024
I72.1 Aneurysm of artery of upper extremity
0.000 0.976 0.024
C17.9 Small intestine, unspecified
0.000 0.977 0.023
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.977 0.023
C26.8 Overlapping lesion of digestive system
0.000 0.977 0.022
C26.1 Spleen
0.000 0.977 0.022
E04.0 Non-toxic diffuse goitre
0.002 0.978 0.021
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.978 0.022
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.978 0.022
E83.5 Disorders of calcium metabolism
0.007 0.978 0.015
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.022 0.978 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.978 0.021
E66.0 Obesity due to excess calories
0.000 0.979 0.021
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.979 0.021
I70.8 Atherosclerosis of other arteries
0.000 0.979 0.021
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.979 0.021
I70.9 Generalised and unspecified atherosclerosis
0.000 0.979 0.021
I70.1 Atherosclerosis of renal artery
0.000 0.979 0.021
I72.9 Aneurysm of unspecified site
0.000 0.979 0.021
E26.0 Primary hyperaldosteronism
0.001 0.979 0.020
E23.6 Other disorders of pituitary gland
0.000 0.979 0.020
M49 Spondylopathies in diseases classified elsewhere
0.020 0.979 0.000
M46 Other inflammatory spondylopathies
0.020 0.980 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.980 0.020
I72.2 Aneurysm of renal artery
0.000 0.980 0.020
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.980 0.020
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.980 0.020
E23.2 Diabetes insipidus
0.000 0.980 0.020
M46.9 Inflammatory spondylopathy, unspecified
0.020 0.980 0.000
I79.1 Aortitis in diseases classified elsewhere
0.000 0.980 0.019
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.980 0.019
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.019 0.980 0.000
C22.7 Other specified carcinomas of liver
0.000 0.981 0.019
C22.4 Other sarcomas of liver
0.000 0.981 0.019
C22.3 Angiosarcoma of liver
0.000 0.981 0.019

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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