TreeWAS – Variant ID: rs16982689

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H65-H75 Diseases of middle ear and mastoid	0.024	0.976	0.000
H73 Other disorders of tympanic membrane	0.023	0.977	0.000
H73.8 Other specified disorders of tympanic membrane	0.022	0.978	0.000
H65 Nonsuppurative otitis media	0.022	0.978	0.000
Chapter VIII Diseases of the ear and mastoid process	0.021	0.979	0.000
H60-H62 Diseases of external ear	0.021	0.979	0.000
H72 Perforation of tympanic membrane	0.020	0.980	0.000
H61 Other disorders of external ear	0.020	0.980	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.019	0.981	0.000
H61.0 Perichondritis of external ear	0.019	0.981	0.000
R41.0 Disorientation, unspecified	0.000	0.981	0.019
H69 Other disorders of Eustachian tube	0.018	0.981	0.000
H74 Other disorders of middle ear and mastoid	0.018	0.981	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.018	0.982	0.000
H66 Suppurative and unspecified otitis media	0.018	0.982	0.000
H60 Otitis externa	0.018	0.982	0.000
H65.2 Chronic serous otitis media	0.018	0.982	0.000
H80-H83 Diseases of inner ear	0.017	0.983	0.000
H90-H95 Other disorders of ear	0.017	0.983	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.017	0.983	0.000
H70 Mastoiditis and related conditions	0.017	0.983	0.000
H68 Eustachian salpingitis and obstruction	0.017	0.983	0.000
H67 Otitis media in diseases classified elsewhere	0.017	0.983	0.000
H61.2 Impacted cerumen	0.017	0.983	0.000
H65.3 Chronic mucoid otitis media	0.017	0.983	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.016	0.984	0.000
H73.1 Chronic myringitis	0.016	0.984	0.000
H73.0 Acute myringitis	0.016	0.984	0.000
H65.4 Other chronic nonsuppurative otitis media	0.016	0.984	0.000
H65.1 Other acute nonsuppurative otitis media	0.016	0.984	0.000
H65.0 Acute serous otitis media	0.016	0.984	0.000
H60.9 Otitis externa, unspecified	0.016	0.984	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.015	0.985	0.000
H69.9 Eustachian tube disorder, unspecified	0.015	0.985	0.000
H72.8 Other perforations of tympanic membrane	0.015	0.985	0.000
H72.2 Other marginal perforations of tympanic membrane	0.015	0.985	0.000
H72.1 Attic perforation of tympanic membrane	0.015	0.985	0.000
H74.4 Polyp of middle ear	0.015	0.985	0.000
H61.9 Disorder of external ear, unspecified	0.014	0.985	0.000
H61.8 Other specified disorders of external ear	0.014	0.985	0.000
H61.3 Acquired stenosis of external ear canal	0.014	0.985	0.000
H61.1 Non-infective disorders of pinna	0.014	0.985	0.000
H83 Other diseases of inner ear	0.014	0.986	0.000
H90 Conductive and sensorineural hearing loss	0.014	0.986	0.000
H92 Otalgia and effusion of ear	0.014	0.986	0.000
H66.3 Other chronic suppurative otitis media	0.014	0.986	0.000
H81 Disorders of vestibular function	0.014	0.986	0.000
H69.8 Other specified disorders of Eustachian tube	0.013	0.986	0.000
H69.0 Patulous Eustachian tube	0.013	0.986	0.000
H71 Cholesteatoma of middle ear	0.013	0.986	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.013	0.986	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.013	0.986	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.013	0.986	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.013	0.986	0.000
H74.1 Adhesive middle ear disease	0.013	0.986	0.000
H74.0 Tympanosclerosis	0.013	0.986	0.000
H72.0 Central perforation of tympanic membrane	0.013	0.986	0.000
H66.4 Suppurative otitis media, unspecified	0.013	0.987	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.013	0.987	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.013	0.987	0.000
H66.0 Acute suppurative otitis media	0.013	0.987	0.000
H60.8 Other otitis externa	0.013	0.987	0.000
H60.5 Acute otitis externa, non-infective	0.013	0.987	0.000
H60.4 Cholesteatoma of external ear	0.013	0.987	0.000
H60.3 Other infective otitis externa	0.013	0.987	0.000
H60.2 Malignant otitis externa	0.013	0.987	0.000
H60.1 Cellulitis of external ear	0.013	0.987	0.000
H60.0 Abscess of external ear	0.013	0.987	0.000
H66.9 Otitis media, unspecified	0.013	0.987	0.000
H90.2 Conductive hearing loss, unspecified	0.013	0.987	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.013	0.987	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.013	0.987	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.013	0.987	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.012	0.987	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.012	0.987	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.012	0.987	0.000
H68.1 Obstruction of Eustachian tube	0.012	0.987	0.000
H68.0 Eustachian salpingitis	0.012	0.987	0.000
H70.9 Mastoiditis, unspecified	0.012	0.987	0.000
H70.8 Other mastoiditis and related conditions	0.012	0.987	0.000
H70.2 Petrositis	0.012	0.987	0.000
H70.1 Chronic mastoiditis	0.012	0.987	0.000
H70.0 Acute mastoiditis	0.012	0.987	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.012	0.987	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.012	0.987	0.000
H92.0 Otalgia	0.012	0.988	0.000
H83.0 Labyrinthitis	0.012	0.988	0.000
H81.1 Benign paroxysmal vertigo	0.012	0.988	0.000
H93 Other disorders of ear, not elsewhere classified	0.012	0.988	0.000
H80 Otosclerosis	0.012	0.988	0.000
I35.0 Aortic (valve) stenosis	0.012	0.988	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.011	0.989	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.011	0.989	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.011	0.989	0.000
H62.2 Otitis externa in mycoses	0.011	0.989	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.011	0.989	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.011	0.989	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.011	0.989	0.000
H91 Other hearing loss	0.011	0.989	0.000
I35 Nonrheumatic aortic valve disorders	0.011	0.989	0.000
H83.9 Disease of inner ear, unspecified	0.010	0.989	0.000
H83.8 Other specified diseases of inner ear	0.010	0.989	0.000
H83.3 Noise effects on inner ear	0.010	0.989	0.000
H83.2 Labyrinthine dysfunction	0.010	0.989	0.000
H83.1 Labyrinthine fistula	0.010	0.989	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.010	0.989	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.010	0.989	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.010	0.989	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.010	0.989	0.000
H90.0 Conductive hearing loss, bilateral	0.010	0.989	0.000
H92.2 Otorrhagia	0.010	0.989	0.000
H92.1 Otorrhoea	0.010	0.990	0.000
I35.1 Aortic (valve) insufficiency	0.010	0.990	0.000
H81.9 Disorder of vestibular function, unspecified	0.010	0.990	0.000
H81.8 Other disorders of vestibular function	0.010	0.990	0.000
H81.4 Vertigo of central origin	0.010	0.990	0.000
H81.3 Other peripheral vertigo	0.010	0.990	0.000
H81.2 Vestibular neuronitis	0.010	0.990	0.000
I35.8 Other aortic valve disorders	0.010	0.990	0.000
H90.5 Sensorineural hearing loss, unspecified	0.009	0.990	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.009	0.990	0.000
H90.3 Sensorineural hearing loss, bilateral	0.009	0.991	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.009	0.991	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.009	0.991	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.009	0.991	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.009	0.991	0.000
H95.1 Other disorders following mastoidectomy	0.009	0.991	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.009	0.991	0.000
H93.9 Disorder of ear, unspecified	0.009	0.991	0.000
H93.8 Other specified disorders of ear	0.009	0.991	0.000
H93.3 Disorders of acoustic nerve	0.009	0.991	0.000
H93.2 Other abnormal auditory perceptions	0.009	0.991	0.000
H93.0 Degenerative and vascular disorders of ear	0.009	0.991	0.000
I35.9 Aortic valve disorder, unspecified	0.009	0.991	0.000
H80.8 Other otosclerosis	0.009	0.991	0.000
H80.2 Cochlear otosclerosis	0.009	0.991	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.009	0.991	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.009	0.991	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.000	0.991	0.009
H93.1 Tinnitus	0.008	0.991	0.000
H91.8 Other specified hearing loss	0.008	0.992	0.000
H91.3 Deaf mutism, not elsewhere classified	0.008	0.992	0.000
H91.2 Sudden idiopathic hearing loss	0.008	0.992	0.000
H91.1 Presbycusis	0.008	0.992	0.000
H91.0 Ototoxic hearing loss	0.008	0.992	0.000
H80.9 Otosclerosis, unspecified	0.008	0.992	0.000
H81.0 Meniere's disease	0.008	0.992	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.000	0.993	0.007
H91.9 Hearing loss, unspecified	0.007	0.993	0.000
R41.2 Retrograde amnesia	0.000	0.994	0.006
R41.1 Anterograde amnesia	0.000	0.994	0.006
D12.6 Colon, unspecified	0.006	0.994	0.000
R41.3 Other amnesia	0.000	0.994	0.006
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.005	0.995	0.000
D12.7 Rectosigmoid junction	0.005	0.995	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.005	0.995	0.000
D12.1 Appendix	0.005	0.995	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.005	0.995	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.004	0.996	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.004	0.996	0.000
S80-S89 Injuries to the knee and lower leg	0.004	0.996	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.004	0.996	0.000
D12.4 Descending colon	0.004	0.996	0.000
D12.8 Rectum	0.004	0.996	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.004	0.996	0.000
S90-S99 Injuries to the ankle and foot	0.004	0.996	0.000
T66-T78 Other and unspecified effects of external causes	0.004	0.996	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
S40-S49 Injuries to the shoulder and upper arm	0.004	0.996	0.000
R39.1 Other difficulties with micturition	0.000	0.996	0.004
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.004	0.996	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.004	0.996	0.000
D12.9 Anus and anal canal	0.004	0.996	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.004	0.996	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.004	0.996	0.000
S80 Superficial injury of lower leg	0.004	0.996	0.000
T85.2 Mechanical complication of intraocular lens	0.004	0.996	0.000
S60-S69 Injuries to the wrist and hand	0.004	0.996	0.000
D12.2 Ascending colon	0.004	0.996	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.004	0.996	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.004	0.996	0.000
T78.4 Allergy, unspecified	0.004	0.996	0.000
T78 Adverse effects, not elsewhere classified	0.004	0.996	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.004	0.996	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.004	0.996	0.000
S80.9 Superficial injury of lower leg, unspecified	0.004	0.996	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.000	0.996	0.004
T83.1 Mechanical complication of other urinary devices and implants	0.004	0.996	0.000
T92 Sequelae of injuries of upper limb	0.004	0.996	0.000
S92 Fracture of foot, except ankle	0.004	0.996	0.000
D12.3 Transverse colon	0.004	0.996	0.000
T93 Sequelae of injuries of lower limb	0.004	0.996	0.000
S81 Open wound of lower leg	0.004	0.996	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.004	0.996	0.000
S41 Open wound of shoulder and upper arm	0.004	0.996	0.000
S70-S79 Injuries to the hip and thigh	0.004	0.996	0.000
S82 Fracture of lower leg, including ankle	0.004	0.996	0.000
S10-S19 Injuries to the neck	0.004	0.996	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.004	0.996	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
T33-T35 Frostbite	0.004	0.996	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.004	0.996	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.004	0.996	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.004	0.996	0.000
T00-T07 Injuries involving multiple body regions	0.004	0.996	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.004	0.996	0.000
T79-T79 Certain early complications of trauma	0.004	0.996	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.004	0.996	0.000
D43.2 Brain, unspecified	0.004	0.996	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.004	0.996	0.000
T91 Sequelae of injuries of neck and trunk	0.003	0.996	0.000
S92.0 Fracture of calcaneus	0.003	0.996	0.000
T90 Sequelae of injuries of head	0.003	0.996	0.000
D24 Benign neoplasm of breast	0.004	0.996	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.996	0.000
D50.8 Other iron deficiency anaemias	0.004	0.996	0.000
T92.1 Sequelae of fracture of arm	0.003	0.996	0.000
S89 Other and unspecified injuries of lower leg	0.003	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.996	0.000
S20-S29 Injuries to the thorax	0.003	0.996	0.000
S82.2 Fracture of shaft of tibia	0.003	0.996	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.003	0.996	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.003	0.996	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.003	0.996	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.003	0.996	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.003	0.996	0.000
T98 Sequelae of other and unspecified effects of external causes	0.003	0.997	0.000
T95 Sequelae of burns, corrosions and frostbite	0.003	0.997	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.003	0.997	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
S82.20 Fracture of shaft of tibia (closed)	0.003	0.997	0.000
S92.00 Fracture of calcaneus (closed)	0.003	0.997	0.000
D12.5 Sigmoid colon	0.003	0.997	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.003	0.997	0.000
S88 Traumatic amputation of lower leg	0.003	0.997	0.000
S87 Crushing injury of lower leg	0.003	0.997	0.000
S86 Injury of muscle and tendon at lower leg level	0.003	0.997	0.000
S85 Injury of blood vessels at lower leg level	0.003	0.997	0.000
S84 Injury of nerves at lower leg level	0.003	0.997	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.003	0.997	0.000
S40 Superficial injury of shoulder and upper arm	0.003	0.997	0.000
S69 Other and unspecified injuries of wrist and hand	0.003	0.997	0.000
S50-S59 Injuries to the elbow and forearm	0.003	0.997	0.000
M47.9 Spondylosis, unspecified	0.003	0.997	0.000
S61 Open wound of wrist and hand	0.003	0.997	0.000
S91 Open wound of ankle and foot	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.003	0.997	0.000
S41.1 Open wound of upper arm	0.003	0.997	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.003	0.997	0.000
R39 Other symptoms and signs involving the urinary system	0.000	0.997	0.003
T17 Foreign body in respiratory tract	0.003	0.997	0.000
T86 Failure and rejection of transplanted organs and tissues	0.003	0.997	0.000
S48 Traumatic amputation of shoulder and upper arm	0.003	0.997	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.003	0.997	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.003	0.997	0.000
S44 Injury of nerves at shoulder and upper arm level	0.003	0.997	0.000
S47 Crushing injury of shoulder and upper arm	0.003	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.003	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.003	0.997	0.000
S97 Crushing injury of ankle and foot	0.003	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.003	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.003	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.003	0.997	0.000
S90 Superficial injury of ankle and foot	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.003	0.997	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
T75 Effects of other external causes	0.003	0.997	0.000
T74 Maltreatment syndromes	0.003	0.997	0.000
T73 Effects of other deprivation	0.003	0.997	0.000
T70 Effects of air pressure and water pressure	0.003	0.997	0.000
T69 Other effects of reduced temperature	0.003	0.997	0.000
T67 Effects of heat and light	0.003	0.997	0.000
T71 Asphyxiation	0.003	0.997	0.000
T68 Hypothermia	0.003	0.997	0.000
T66 Unspecified effects of radiation	0.003	0.997	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.003	0.997	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.003	0.997	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.003	0.997	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.003	0.997	0.000
T83.2 Mechanical complication of graft of urinary organ	0.003	0.997	0.000
T18 Foreign body in alimentary tract	0.003	0.997	0.000
T87 Complications peculiar to reattachment and amputation	0.003	0.997	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.003	0.997	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.003	0.997	0.000
D13.1 Stomach	0.003	0.997	0.000
C20 Malignant neoplasm of rectum	0.003	0.997	0.000
S80.0 Contusion of knee	0.003	0.997	0.000
D12.0 Caecum	0.003	0.997	0.000
S80.8 Other superficial injuries of lower leg	0.003	0.997	0.000
S80.7 Multiple superficial injuries of lower leg	0.003	0.997	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.003	0.997	0.000
S65 Injury of blood vessels at wrist and hand level	0.003	0.997	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.003	0.997	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.003	0.997	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.003	0.997	0.000
S43.0 Dislocation of shoulder joint	0.003	0.997	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.003	0.997	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.003	0.997	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.003	0.997	0.000
S81.8 Open wound of other parts of lower leg	0.003	0.997	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
T80.6 Other serum reactions	0.003	0.997	0.000
T80.5 Anaphylactic shock due to serum	0.003	0.997	0.000
T80.4 Rh incompatibility reaction	0.003	0.997	0.000
T80.3 ABO incompatibility reaction	0.003	0.997	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.003	0.997	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.003	0.997	0.000
T19 Foreign body in genito-urinary tract	0.003	0.997	0.000
T15 Foreign body on external eye	0.003	0.997	0.000
T16 Foreign body in ear	0.003	0.997	0.000
D10-D36 Benign neoplasms	0.003	0.997	0.000
C15-C26 Malignant neoplasms of digestive organs	0.003	0.997	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
T78.9 Adverse effect, unspecified	0.003	0.997	0.000
T78.8 Other adverse effects, not elsewhere classified	0.003	0.997	0.000
T78.3 Angioneurotic oedema	0.003	0.997	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.003	0.997	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.003	0.997	0.000
S72 Fracture of femur	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.003	0.997	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.003	0.997	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.003	0.997	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.003	0.997	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.003	0.997	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.003	0.997	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.003	0.997	0.000
D45 Polycythaemia vera	0.003	0.997	0.000
S81.0 Open wound of knee	0.003	0.997	0.000
T39.0 Salicylates	0.003	0.997	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.003	0.997	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.003	0.997	0.000
S60 Superficial injury of wrist and hand	0.003	0.997	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
S82.0 Fracture of patella	0.003	0.997	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.003	0.997	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.003	0.997	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.003	0.997	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.003	0.997	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.003	0.997	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.003	0.997	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.003	0.997	0.000
T92.0 Sequelae of open wound of upper limb	0.003	0.997	0.000
S71 Open wound of hip and thigh	0.003	0.997	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.003	0.997	0.000
S92.3 Fracture of metatarsal bone	0.003	0.997	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
T88.4 Failed or difficult intubation	0.003	0.997	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.003	0.997	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.003	0.997	0.000
S67 Crushing injury of wrist and hand	0.003	0.997	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.003	0.997	0.000
S82.1 Fracture of upper end of tibia	0.003	0.997	0.000
S92.9 Fracture of foot, unspecified	0.003	0.997	0.000
S92.7 Multiple fractures of foot	0.003	0.997	0.000
S92.5 Fracture of other toe	0.003	0.997	0.000
S92.4 Fracture of great toe	0.003	0.997	0.000
S92.2 Fracture of other tarsal bone(s)	0.003	0.997	0.000
S92.1 Fracture of talus	0.003	0.997	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.003	0.997	0.000
T93.2 Sequelae of other fractures of lower limb	0.003	0.997	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
S61.1 Open wound of finger(s) with damage to nail	0.003	0.997	0.000
S42 Fracture of shoulder and upper arm	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
T91.3 Sequelae of injury of spinal cord	0.003	0.997	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.003	0.997	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.003	0.997	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.003	0.997	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.003	0.997	0.000
T93.1 Sequelae of fracture of femur	0.003	0.997	0.000
T93.0 Sequelae of open wound of lower limb	0.003	0.997	0.000
S81.7 Multiple open wounds of lower leg	0.003	0.997	0.000
T90.4 Sequelae of injury of eye and orbit	0.003	0.997	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.003	0.997	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.003	0.997	0.000
S41.0 Open wound of shoulder	0.003	0.997	0.000
S69.9 Unspecified injury of wrist and hand	0.003	0.997	0.000
S81.9 Open wound of lower leg, part unspecified	0.003	0.997	0.000
S12 Fracture of neck	0.003	0.997	0.000
S82.4 Fracture of fibula alone	0.003	0.997	0.000
T78.2 Anaphylactic shock, unspecified	0.003	0.997	0.000
T86.1 Kidney transplant failure and rejection	0.003	0.997	0.000
S50 Superficial injury of forearm	0.003	0.997	0.000
S64 Injury of nerves at wrist and hand level	0.003	0.997	0.000
S78 Traumatic amputation of hip and thigh	0.003	0.997	0.000
S77 Crushing injury of hip and thigh	0.003	0.997	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.003	0.997	0.000
S75 Injury of blood vessels at hip and thigh level	0.003	0.997	0.000
S74 Injury of nerves at hip and thigh level	0.003	0.997	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.003	0.997	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.003	0.997	0.000
S82.9 Fracture of lower leg, part unspecified	0.003	0.997	0.000
S82.7 Multiple fractures of lower leg	0.003	0.997	0.000
S19 Other and unspecified injuries of neck	0.003	0.997	0.000
S17 Crushing injury of neck	0.003	0.997	0.000
S15 Injury of blood vessels at neck level	0.003	0.997	0.000
S14 Injury of nerves and spinal cord at neck level	0.003	0.997	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.003	0.997	0.000
S11 Open wound of neck	0.003	0.997	0.000
S10 Superficial injury of neck	0.003	0.997	0.000
S18 Traumatic amputation at neck level	0.003	0.997	0.000
S16 Injury of muscle and tendon at neck level	0.003	0.997	0.000
S68 Traumatic amputation of wrist and hand	0.003	0.997	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.003	0.997	0.000
D44.0 Thyroid gland	0.003	0.997	0.000
D48.5 Skin	0.003	0.997	0.000
G43.9 Migraine, unspecified	0.000	0.997	0.003
S93.1 Dislocation of toe(s)	0.003	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.003	0.997	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.003	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.003	0.997	0.000
N23 Unspecified renal colic	0.000	0.997	0.003
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.003	0.997	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.003	0.997	0.000
T05 Traumatic amputations involving multiple body regions	0.003	0.997	0.000
T04 Crushing injuries involving multiple body regions	0.003	0.997	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.003	0.997	0.000
T02 Fractures involving multiple body regions	0.003	0.997	0.000
T01 Open wounds involving multiple body regions	0.003	0.997	0.000
T00 Superficial injuries involving multiple body regions	0.003	0.997	0.000
T07 Unspecified multiple injuries	0.003	0.997	0.000
T14 Injury of unspecified body region	0.003	0.997	0.000
T13 Other injuries of lower limb, level unspecified	0.003	0.997	0.000
T11 Other injuries of upper limb, level unspecified	0.003	0.997	0.000
T09 Other injuries of spine and trunk, level unspecified	0.003	0.997	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.003	0.997	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.003	0.997	0.000
T12 Fracture of lower limb, level unspecified	0.003	0.997	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.003	0.997	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.003	0.997	0.000
T10 Fracture of upper limb, level unspecified	0.003	0.997	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.003	0.997	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.003	0.997	0.000
T08 Fracture of spine, level unspecified	0.003	0.997	0.000
T25 Burn and corrosion of ankle and foot	0.003	0.997	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T23 Burn and corrosion of wrist and hand	0.003	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
T21 Burn and corrosion of trunk	0.003	0.997	0.000
T20 Burn and corrosion of head and neck	0.003	0.997	0.000
T28 Burn and corrosion of other internal organs	0.003	0.997	0.000
T27 Burn and corrosion of respiratory tract	0.003	0.997	0.000
T26 Burn and corrosion confined to eye and adnexa	0.003	0.997	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.003	0.997	0.000
T34 Frostbite with tissue necrosis	0.003	0.997	0.000
T33 Superficial frostbite	0.003	0.997	0.000
D10 Benign neoplasm of mouth and pharynx	0.003	0.997	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.003	0.997	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.003	0.997	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.003	0.997	0.000
S43.4 Sprain and strain of shoulder joint	0.003	0.997	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.003	0.997	0.000
S43.2 Dislocation of sternoclavicular joint	0.003	0.997	0.000
S43.1 Dislocation of acromioclavicular joint	0.003	0.997	0.000
S82.6 Fracture of lateral malleolus	0.003	0.997	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.003	0.997	0.000
T65 Toxic effect of other and unspecified substances	0.003	0.997	0.000
T63 Toxic effect of contact with venomous animals	0.003	0.997	0.000
T62 Toxic effect of other noxious substances eaten as food	0.003	0.997	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.003	0.997	0.000
T60 Toxic effect of pesticides	0.003	0.997	0.000
T59 Toxic effect of other gases, fumes and vapours	0.003	0.997	0.000
T57 Toxic effect of other inorganic substances	0.003	0.997	0.000
T56 Toxic effect of metals	0.003	0.997	0.000
T54 Toxic effect of corrosive substances	0.003	0.997	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.003	0.997	0.000
T52 Toxic effect of organic solvents	0.003	0.997	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.003	0.997	0.000
T58 Toxic effect of carbon monoxide	0.003	0.997	0.000
T55 Toxic effect of soaps and detergents	0.003	0.997	0.000
S92.01 Fracture of calcaneus (open)	0.003	0.997	0.000
D10.1 Tongue	0.003	0.997	0.000
S82.3 Fracture of lower end of tibia	0.003	0.997	0.000
S89.9 Unspecified injury of lower leg	0.003	0.997	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.003	0.997	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.003	0.997	0.000
T39.4 Antirheumatics, not elsewhere classified	0.003	0.997	0.000
T39.2 Pyrazolone derivatives	0.003	0.997	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.003	0.997	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.003	0.997	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.003	0.997	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.003	0.997	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.003	0.997	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations