TreeWAS – Variant ID: rs17023457

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C71.9 Brain, unspecified	0.015	0.985	0.000
H61.0 Perichondritis of external ear	0.014	0.986	0.000
H61 Other disorders of external ear	0.014	0.986	0.000
H61.3 Acquired stenosis of external ear canal	0.013	0.987	0.000
H60 Otitis externa	0.012	0.988	0.000
C71 Malignant neoplasm of brain	0.012	0.988	0.000
C71.3 Parietal lobe	0.012	0.988	0.000
I84.6 Residual haemorrhoidal skin tags	0.000	0.988	0.012
H60-H62 Diseases of external ear	0.012	0.988	0.000
H61.8 Other specified disorders of external ear	0.012	0.988	0.000
C71.2 Temporal lobe	0.011	0.988	0.000
H60.5 Acute otitis externa, non-infective	0.011	0.989	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.011	0.989	0.000
H60.1 Cellulitis of external ear	0.011	0.989	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.011	0.989	0.000
H61.1 Non-infective disorders of pinna	0.010	0.990	0.000
H60.8 Other otitis externa	0.010	0.990	0.000
H61.2 Impacted cerumen	0.010	0.990	0.000
C71.0 Cerebrum, except lobes and ventricles	0.010	0.990	0.000
H60.4 Cholesteatoma of external ear	0.010	0.990	0.000
H60.3 Other infective otitis externa	0.010	0.990	0.000
H60.0 Abscess of external ear	0.009	0.991	0.000
H60.2 Malignant otitis externa	0.009	0.991	0.000
C71.7 Brain stem	0.009	0.991	0.000
C71.6 Cerebellum	0.009	0.991	0.000
C71.5 Cerebral ventricle	0.009	0.991	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.009	0.991	0.000
H61.9 Disorder of external ear, unspecified	0.008	0.992	0.000
C71.4 Occipital lobe	0.008	0.992	0.000
C71.8 Overlapping lesion of brain	0.007	0.993	0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.007	0.993	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.007	0.993	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.006	0.993	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.006	0.993	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.006	0.993	0.000
H62.2 Otitis externa in mycoses	0.006	0.993	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.006	0.993	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.006	0.993	0.000
C71.1 Frontal lobe	0.006	0.994	0.000
Q23.1 Congenital insufficiency of aortic valve	0.006	0.994	0.000
H60.9 Otitis externa, unspecified	0.006	0.994	0.000
M86.9 Osteomyelitis, unspecified	0.006	0.994	0.000
Q23 Congenital malformations of aortic and mitral valves	0.006	0.994	0.000
M35.0 Sicca syndrome [Sjogren]	0.006	0.994	0.000
K31 Other diseases of stomach and duodenum	0.005	0.995	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.005	0.995	0.000
K31.4 Gastric diverticulum	0.005	0.995	0.000
K31.5 Obstruction of duodenum	0.005	0.995	0.000
M24.1 Other articular cartilage disorders	0.005	0.995	0.000
K31.1 Adult hypertrophic pyloric stenosis	0.005	0.995	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.005	0.995	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.004	0.995	0.000
Q23.3 Congenital mitral insufficiency	0.004	0.995	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.004	0.996	0.000
X49.9 Unspecified place	0.004	0.996	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.996	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.004	0.996	0.000
M86.93 Osteomyelitis, unspecified (Forearm)	0.004	0.996	0.000
M86.92 Osteomyelitis, unspecified (Upper arm)	0.004	0.996	0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.004	0.996	0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.004	0.996	0.000
Q24 Other congenital malformations of heart	0.004	0.996	0.000
K31.2 Hourglass stricture and stenosis of stomach	0.004	0.996	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.004	0.996	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.004	0.996	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q23.4 Hypoplastic left heart syndrome	0.004	0.996	0.000
Q23.2 Congenital mitral stenosis	0.004	0.996	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.996	0.000
Q23.0 Congenital stenosis of aortic valve	0.004	0.996	0.000
M86 Osteomyelitis	0.004	0.996	0.000
Q25 Congenital malformations of great arteries	0.004	0.996	0.000
I21.4 Acute subendocardial myocardial infarction	0.004	0.996	0.000
Q28.3 Other malformations of cerebral vessels	0.004	0.996	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.004	0.996	0.000
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
K31.3 Pylorospasm, not elsewhere classified	0.004	0.996	0.000
K31.0 Acute dilatation of stomach	0.004	0.996	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.004	0.996	0.000
I49.8 Other specified cardiac arrhythmias	0.004	0.996	0.000
K31.6 Fistula of stomach and duodenum	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.004	0.996	0.000
M24.18 Other articular cartilage disorders (Other)	0.004	0.996	0.000
M24.14 Other articular cartilage disorders (Hand)	0.004	0.996	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.004	0.996	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.004	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.004	0.996	0.000
Z93.0 Tracheostomy status	0.004	0.996	0.000
Q26 Congenital malformations of great veins	0.004	0.996	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q27 Other congenital malformations of peripheral vascular system	0.004	0.996	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.004	0.996	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.004	0.996	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.004	0.996	0.000
M24.6 Ankylosis of joint	0.004	0.996	0.000
Q25.4 Other congenital malformations of aorta	0.004	0.996	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.996	0.004
M86.1 Other acute osteomyelitis	0.003	0.996	0.000
M89.8 Other specified disorders of bone	0.003	0.996	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.003	0.997	0.000
Q25.6 Stenosis of pulmonary artery	0.003	0.997	0.000
M24.64 Ankylosis of joint (Hand)	0.003	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.997	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.003	0.997	0.000
M86.8 Other osteomyelitis	0.003	0.997	0.000
Z93.3 Colostomy status	0.003	0.997	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.003	0.997	0.000
C15.5 Lower third of oesophagus	0.000	0.997	0.003
Q24.4 Congenital subaortic stenosis	0.003	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.003	0.997	0.000
Q24.2 Cor triatriatum	0.003	0.997	0.000
Q24.1 Levocardia	0.003	0.997	0.000
Q24.0 Dextrocardia	0.003	0.997	0.000
M86.6 Other chronic osteomyelitis	0.003	0.997	0.000
Z93.5 Cystostomy status	0.003	0.997	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.003	0.997	0.000
Z93 Artificial opening status	0.003	0.997	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.003	0.997	0.000
R49.0 Dysphonia	0.000	0.997	0.003
C70 Malignant neoplasm of meninges	0.003	0.997	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.997	0.000
Q22.5 Ebstein's anomaly	0.003	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.997	0.000
Q22.0 Pulmonary valve atresia	0.003	0.997	0.000
L29.9 Pruritus, unspecified	0.000	0.997	0.003
M86.5 Other chronic haematogenous osteomyelitis	0.003	0.997	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.003	0.997	0.000
M86.3 Chronic multifocal osteomyelitis	0.003	0.997	0.000
M86.2 Subacute osteomyelitis	0.003	0.997	0.000
M86.0 Acute haematogenous osteomyelitis	0.003	0.997	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.997	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.997	0.000
Q25.3 Stenosis of aorta	0.003	0.997	0.000
Q25.2 Atresia of aorta	0.003	0.997	0.000
Q25.0 Patent ductus arteriosus	0.003	0.997	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.003	0.997	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.003	0.997	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.003	0.997	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.997	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.003	0.997	0.000
M86.17 Other acute osteomyelitis (Ankle and foot)	0.003	0.997	0.000
M24.66 Ankylosis of joint (Lower leg)	0.003	0.997	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.003	0.997	0.000
Q21 Congenital malformations of cardiac septa	0.003	0.997	0.000
Z93.4 Other artificial openings of gastro-intestinal tract status	0.003	0.997	0.000
Q25.1 Coarctation of aorta	0.003	0.997	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.003	0.997	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.997	0.000
Q20.4 Double inlet ventricle	0.003	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.997	0.000
Q20.2 Double outlet left ventricle	0.003	0.997	0.000
Q20.1 Double outlet right ventricle	0.003	0.997	0.000
Q20.0 Common arterial trunk	0.003	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.003	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.1 Persistent left superior vena cava	0.003	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
C69 Malignant neoplasm of eye and adnexa	0.003	0.997	0.000
Q21.3 Tetralogy of Fallot	0.003	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.003	0.997	0.000
M24.68 Ankylosis of joint (Other)	0.003	0.997	0.000
M24.63 Ankylosis of joint (Forearm)	0.003	0.997	0.000
M24.62 Ankylosis of joint (Upper arm)	0.003	0.997	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.003	0.997	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.003	0.997	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.003	0.997	0.000
M86.86 Other osteomyelitis (Lower leg)	0.003	0.997	0.000
C82.0 Small cleaved cell, follicular	0.003	0.997	0.000
K66.8 Other specified disorders of peritoneum	0.000	0.997	0.003
M89.84 Other specified disorders of bone (Hand)	0.003	0.997	0.000
C82.3 Follicular lymphoma grade IIIa	0.003	0.997	0.000
M86.19 Other acute osteomyelitis (Site unspecified)	0.003	0.997	0.000
M86.18 Other acute osteomyelitis (Other)	0.003	0.997	0.000
M86.16 Other acute osteomyelitis (Lower leg)	0.003	0.997	0.000
M86.15 Other acute osteomyelitis (Pelvic region and thigh)	0.003	0.997	0.000
M86.14 Other acute osteomyelitis (Hand)	0.003	0.997	0.000
M86.13 Other acute osteomyelitis (Forearm)	0.003	0.997	0.000
M86.12 Other acute osteomyelitis (Upper arm)	0.003	0.997	0.000
M86.11 Other acute osteomyelitis (Shoulder region)	0.003	0.997	0.000
M86.10 Other acute osteomyelitis (Multiple sites)	0.003	0.997	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.003	0.997	0.000
Z89.4 Acquired absence of foot and ankle	0.003	0.997	0.000
M35 Other systemic involvement of connective tissue	0.003	0.997	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.003	0.997	0.000
M89.83 Other specified disorders of bone (Forearm)	0.003	0.997	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.003	0.997	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.003	0.997	0.000
Z89.9 Acquired absence of limb, unspecified	0.003	0.997	0.000
Z93.6 Other artificial openings of urinary tract status	0.003	0.997	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.003	0.997	0.000
C82.4 Follicular lymphoma grade IIIb	0.003	0.997	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.003	0.997	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.003	0.997	0.000
C69.6 Orbit	0.003	0.997	0.000
M24 Other specific joint derangements	0.003	0.997	0.000
M86.89 Other osteomyelitis (Site unspecified)	0.002	0.997	0.000
M86.88 Other osteomyelitis (Other)	0.002	0.997	0.000
M86.87 Other osteomyelitis (Ankle and foot)	0.002	0.997	0.000
M86.85 Other osteomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M86.84 Other osteomyelitis (Hand)	0.002	0.997	0.000
M86.83 Other osteomyelitis (Forearm)	0.002	0.997	0.000
M86.82 Other osteomyelitis (Upper arm)	0.002	0.997	0.000
M86.81 Other osteomyelitis (Shoulder region)	0.002	0.997	0.000
M86.80 Other osteomyelitis (Multiple sites)	0.002	0.997	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.003	0.997	0.000
M35.7 Hypermobility syndrome	0.003	0.997	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.997	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.002	0.997	0.000
M86.68 Other chronic osteomyelitis (Other)	0.002	0.997	0.000
M86.66 Other chronic osteomyelitis (Lower leg)	0.002	0.997	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.002	0.997	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.002	0.997	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.002	0.997	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.002	0.997	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.002	0.997	0.000
C82.6 Cutaneous follicle centre lymphoma	0.003	0.997	0.000
C82.5 Diffuse follicle centre lymphoma	0.003	0.997	0.000
C70.9 Meninges, unspecified	0.002	0.997	0.000
C70.1 Spinal meninges	0.002	0.997	0.000
C70.0 Cerebral meninges	0.002	0.997	0.000
M86.09 Acute haematogenous osteomyelitis (Site unspecified)	0.002	0.997	0.000
M86.08 Acute haematogenous osteomyelitis (Other)	0.002	0.997	0.000
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)	0.002	0.997	0.000
M86.06 Acute haematogenous osteomyelitis (Lower leg)	0.002	0.997	0.000
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M86.04 Acute haematogenous osteomyelitis (Hand)	0.002	0.997	0.000
M86.03 Acute haematogenous osteomyelitis (Forearm)	0.002	0.997	0.000
M86.02 Acute haematogenous osteomyelitis (Upper arm)	0.002	0.997	0.000
M86.01 Acute haematogenous osteomyelitis (Shoulder region)	0.002	0.997	0.000
M86.00 Acute haematogenous osteomyelitis (Multiple sites)	0.002	0.997	0.000
M86.29 Subacute osteomyelitis (Site unspecified)	0.002	0.997	0.000
M86.28 Subacute osteomyelitis (Other)	0.002	0.997	0.000
M86.27 Subacute osteomyelitis (Ankle and foot)	0.002	0.997	0.000
M86.26 Subacute osteomyelitis (Lower leg)	0.002	0.997	0.000
M86.25 Subacute osteomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M86.24 Subacute osteomyelitis (Hand)	0.002	0.997	0.000
M86.23 Subacute osteomyelitis (Forearm)	0.002	0.997	0.000
M86.22 Subacute osteomyelitis (Upper arm)	0.002	0.997	0.000
M86.21 Subacute osteomyelitis (Shoulder region)	0.002	0.997	0.000
M86.20 Subacute osteomyelitis (Multiple sites)	0.002	0.997	0.000
M86.39 Chronic multifocal osteomyelitis (Site unspecified)	0.002	0.997	0.000
M86.38 Chronic multifocal osteomyelitis (Other)	0.002	0.997	0.000
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)	0.002	0.997	0.000
M86.36 Chronic multifocal osteomyelitis (Lower leg)	0.002	0.997	0.000
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M86.34 Chronic multifocal osteomyelitis (Hand)	0.002	0.997	0.000
M86.33 Chronic multifocal osteomyelitis (Forearm)	0.002	0.997	0.000
M86.32 Chronic multifocal osteomyelitis (Upper arm)	0.002	0.997	0.000
M86.31 Chronic multifocal osteomyelitis (Shoulder region)	0.002	0.997	0.000
M86.30 Chronic multifocal osteomyelitis (Multiple sites)	0.002	0.997	0.000
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)	0.002	0.997	0.000
M86.48 Chronic osteomyelitis with draining sinus (Other)	0.002	0.997	0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.002	0.997	0.000
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)	0.002	0.997	0.000
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)	0.002	0.997	0.000
M86.44 Chronic osteomyelitis with draining sinus (Hand)	0.002	0.997	0.000
M86.43 Chronic osteomyelitis with draining sinus (Forearm)	0.002	0.997	0.000
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)	0.002	0.997	0.000
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)	0.002	0.997	0.000
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)	0.002	0.997	0.000
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)	0.002	0.997	0.000
M86.58 Other chronic haematogenous osteomyelitis (Other)	0.002	0.997	0.000
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)	0.002	0.997	0.000
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)	0.002	0.997	0.000
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M86.54 Other chronic haematogenous osteomyelitis (Hand)	0.002	0.997	0.000
M86.53 Other chronic haematogenous osteomyelitis (Forearm)	0.002	0.997	0.000
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)	0.002	0.997	0.000
M86.51 Other chronic haematogenous osteomyelitis (Shoulder region)	0.002	0.997	0.000
M86.50 Other chronic haematogenous osteomyelitis (Multiple sites)	0.002	0.997	0.000
Z89.5 Acquired absence of leg at or below knee	0.003	0.997	0.000
Z93.9 Artificial opening status, unspecified	0.002	0.997	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.997	0.000
C15.4 Middle third of oesophagus	0.000	0.997	0.003
C72.9 Central nervous system, unspecified	0.002	0.997	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.002	0.997	0.000
C72.5 Other and unspecified cranial nerves	0.002	0.997	0.000
C72.4 Acoustic nerve	0.002	0.997	0.000
C72.3 Optic nerve	0.002	0.997	0.000
C72.2 Olfactory nerve	0.002	0.997	0.000
C72.1 Cauda equina	0.002	0.997	0.000
Z89 Acquired absence of limb	0.003	0.997	0.000
D50.8 Other iron deficiency anaemias	0.003	0.997	0.000
Z93.1 Gastrostomy status	0.003	0.997	0.000
C69.0 Conjunctiva	0.002	0.997	0.000
M35.2 Behcet's disease	0.002	0.997	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.997	0.003
C82.2 Large cell, follicular	0.002	0.997	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.003	0.997	0.000
C72.0 Spinal cord	0.002	0.998	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
C15.9 Oesophagus, unspecified	0.000	0.998	0.002
Q21.0 Ventricular septal defect	0.002	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
C69.8 Overlapping lesion of eye and adnexa	0.002	0.998	0.000
C69.5 Lachrymal gland and duct	0.002	0.998	0.000
C69.4 Ciliary body	0.002	0.998	0.000
C69.2 Retina	0.002	0.998	0.000
C69.1 Cornea	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
Z93.8 Other artificial opening status	0.002	0.998	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.998	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.002	0.998	0.000
M24.7 Protrusio acetabuli	0.002	0.998	0.000
Z85.9 Personal history of malignant neoplasm, unspecified	0.002	0.998	0.000
Z89.6 Acquired absence of leg above knee	0.002	0.998	0.000
M35.1 Other overlap syndromes	0.002	0.998	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.002	0.998	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.002	0.998	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.002	0.998	0.000
M35.5 Multifocal fibrosclerosis	0.002	0.998	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.002	0.998	0.000
X49.4 Street and highway	0.002	0.998	0.000
X49.0 Home	0.002	0.998	0.000
X49.8 Other specified place	0.002	0.998	0.000
X49.7 Farm	0.002	0.998	0.000
X49.6 Industrial and construction area	0.002	0.998	0.000
X49.5 Trade and service area	0.002	0.998	0.000
X49.3 Sports and athletics area	0.002	0.998	0.000
X49.2 School, other institution and public administrative area	0.002	0.998	0.000
X49.1 Residential institution	0.002	0.998	0.000
F00 Dementia in Alzheimer's disease	0.002	0.998	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.002	0.998	0.000
M24.9 Joint derangement, unspecified	0.002	0.998	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.002	0.998	0.000
M35.8 Other specified systemic involvement of connective tissue	0.002	0.998	0.000
Z93.2 Ileostomy status	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.000	0.998	0.002
T39.0 Salicylates	0.000	0.998	0.002
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.002	0.998	0.000
I87.1 Compression of vein	0.000	0.998	0.002
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.002	0.998	0.000
K29.4 Chronic atrophic gastritis	0.000	0.998	0.002
Z89.8 Acquired absence of upper and lower limbs [any level]	0.002	0.998	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.002	0.998	0.000
Z89.1 Acquired absence of hand and wrist	0.002	0.998	0.000
C15.8 Overlapping lesion of oesophagus	0.000	0.998	0.002
C15.2 Abdominal part of oesophagus	0.000	0.998	0.002
C15.1 Thoracic part of oesophagus	0.000	0.998	0.002
C15.0 Cervical part of oesophagus	0.000	0.998	0.002
M89 Other disorders of bone	0.002	0.998	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.002	0.998	0.000
Q17.5 Prominent ear	0.002	0.998	0.000
F03 Unspecified dementia	0.002	0.998	0.000
M86-M90 Other osteopathies	0.002	0.998	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.002	0.998	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.002	0.998	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.002	0.998	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.002	0.998	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.002	0.998	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.002	0.998	0.000
G71.0 Muscular dystrophy	0.002	0.998	0.000
L72.0 Epidermal cyst	0.000	0.998	0.002
Z89.2 Acquired absence of upper limb above wrist	0.002	0.998	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.002	0.998	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.002	0.998	0.000
C15.3 Upper third of oesophagus	0.000	0.998	0.002
C69.9 Eye, unspecified	0.002	0.998	0.000
V18.0 Driver injured in nontraffic accident	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
K90.0 Coeliac disease	0.002	0.998	0.000
M21.26 Flexion deformity (Lower leg)	0.002	0.998	0.000
M24.79 Protrusio acetabuli-Site unspec	0.002	0.998	0.000
M24.78 Protrusio acetabuli-Other	0.002	0.998	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.002	0.998	0.000
M24.76 Protrusio acetabuli-Lower leg	0.002	0.998	0.000
M24.74 Protrusio acetabuli-Hand	0.002	0.998	0.000
M24.73 Protrusio acetabuli-Forearm	0.002	0.998	0.000
M24.72 Protrusio acetabuli-Upper arm	0.002	0.998	0.000
M24.71 Protrusio acetabuli-Shldr region	0.002	0.998	0.000
M24.70 Protrusio acetabuli-Mult sites	0.002	0.998	0.000
C22.0 Liver cell carcinoma	0.002	0.998	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.002	0.998	0.000
M21.6 Other acquired deformities of ankle and foot	0.002	0.998	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
X49.09 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Home; During unspecified activity	0.002	0.998	0.000
X49.48 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Street and highway;While engaged in other specified activities	0.002	0.998	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.002	0.998	0.000
K66.9 Disorder of peritoneum, unspecified	0.000	0.998	0.002
M24.99 Joint derangement, unspecified (Site unspecified)	0.002	0.998	0.000
M24.98 Joint derangement, unspecified (Other)	0.002	0.998	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.002	0.998	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.002	0.998	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M24.94 Joint derangement, unspecified (Hand)	0.002	0.998	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.002	0.998	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.002	0.998	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.002	0.998	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.002	0.998	0.000
I24.8 Other forms of acute ischaemic heart disease	0.002	0.998	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.002	0.998	0.000
M21.2 Flexion deformity	0.002	0.998	0.000
K66 Other disorders of peritoneum	0.000	0.998	0.002
M21.24 Flexion deformity (Hand)	0.002	0.998	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.002	0.998	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.002	0.998	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.998	0.002
S32.00 Fracture of lumbar vertebra (closed)	0.002	0.998	0.000
M33.2 Polymyositis	0.002	0.998	0.000
M89.6 Osteopathy after poliomyelitis	0.002	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.998	0.000
M89.2 Other disorders of bone development and growth	0.002	0.998	0.000
M89.1 Epiphyseal arrest	0.002	0.998	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.002	0.998	0.000
C25.9 Pancreas, unspecified	0.002	0.998	0.000
Q17 Other congenital malformations of ear	0.002	0.998	0.000
K66.0 Peritoneal adhesions	0.000	0.998	0.002
M20.3 Other deformity of hallux (acquired)	0.000	0.998	0.002
M24.5 Contracture of joint	0.002	0.998	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
K90.9 Intestinal malabsorption, unspecified	0.002	0.998	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.002
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.998	0.002
M24.8 Other specific joint derangements, not elsewhere classified	0.002	0.998	0.000
V89.9 Person injured in unspecified vehicle accident	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.002	0.998	0.000
M90 Osteopathies in diseases classified elsewhere	0.002	0.998	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.001	0.998	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.001	0.998	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.001	0.998	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.001	0.998	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.001	0.998	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.001	0.998	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.001	0.998	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.001	0.998	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.001	0.998	0.000
M24.57 Contracture of joint (Ankle and foot)	0.001	0.998	0.000
C69.3 Choroid	0.001	0.998	0.001
M89.0 Algoneurodystrophy	0.002	0.998	0.000
R47.1 Dysarthria and anarthria	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.998	0.002
T39.2 Pyrazolone derivatives	0.000	0.998	0.002
M21.25 Flexion deformity (Pelvic region and thigh)	0.002	0.998	0.000
D10.3 Other and unspecified parts of mouth	0.002	0.998	0.000
W25.9 Unspecified place	0.002	0.998	0.000
M88 Paget's disease of bone [osteitis deformans]	0.002	0.998	0.000
R54 Senility	0.002	0.998	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.002	0.998	0.000
M24.0 Loose body in joint	0.002	0.998	0.000
M89.3 Hypertrophy of bone	0.001	0.998	0.000
R73.9 Hyperglycaemia, unspecified	0.000	0.998	0.002
V17.4 Driver injured in traffic accident	0.002	0.998	0.000
C03.1 Lower gum	0.002	0.998	0.000
M89.5 Osteolysis	0.001	0.998	0.000
M21.29 Flexion deformity (Site unspecified)	0.001	0.998	0.000
M21.28 Flexion deformity (Other)	0.001	0.998	0.000
M21.23 Flexion deformity (Forearm)	0.001	0.998	0.000
M21.22 Flexion deformity (Upper arm)	0.001	0.998	0.000
M21.21 Flexion deformity (Shoulder region)	0.001	0.998	0.000
M21.20 Flexion deformity (Multiple sites)	0.001	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.001	0.998	0.000
C16.5 Lesser curvature of stomach, unspecified	0.002	0.998	0.000
I86.1 Scrotal varices	0.002	0.998	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.001	0.998	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.998	0.002
G30.9 Alzheimer's disease, unspecified	0.002	0.998	0.000
M21 Other acquired deformities of limbs	0.002	0.998	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.002	0.998	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations