TreeWAS – Variant ID: rs17079773

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11 Non-insulin-dependent diabetes mellitus	0.000	0.074	0.926
E10-E14 Diabetes mellitus	0.000	0.080	0.920
E10 Insulin-dependent diabetes mellitus	0.000	0.099	0.901
E11.3 With ophthalmic complications	0.000	0.100	0.900
E11.4 With neurological complications	0.000	0.119	0.881
E10.3 With ophthalmic complications	0.000	0.120	0.880
E86 Volume depletion	0.000	0.137	0.863
E70-E90 Metabolic disorders	0.000	0.137	0.863
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.140	0.860
E11.9 Without complications	0.000	0.170	0.830
E11.5 With peripheral circulatory complications	0.000	0.205	0.794
E83 Disorders of mineral metabolism	0.000	0.218	0.782
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.224	0.776
E10.4 With neurological complications	0.000	0.232	0.767
E11.2 With renal complications	0.000	0.234	0.766
E87.5 Hyperkalaemia	0.000	0.264	0.736
E11.0 With coma	0.000	0.265	0.735
E14 Unspecified diabetes mellitus	0.000	0.269	0.731
E87.6 Hypokalaemia	0.000	0.269	0.731
E11.6 With other specified complications	0.000	0.272	0.728
E10.5 With peripheral circulatory complications	0.000	0.276	0.724
E11.8 With unspecified complications	0.000	0.297	0.703
E73 Lactose intolerance	0.000	0.318	0.682
E14.3 With ophthalmic complications	0.000	0.319	0.681
E11.7 With multiple complications	0.000	0.336	0.664
E83.1 Disorders of iron metabolism	0.000	0.337	0.663
E10.2 With renal complications	0.000	0.339	0.661
E12 Malnutrition-related diabetes mellitus	0.000	0.340	0.660
E10.7 With multiple complications	0.000	0.354	0.646
E10.6 With other specified complications	0.000	0.354	0.646
E10.0 With coma	0.000	0.354	0.646
E87.7 Fluid overload	0.000	0.355	0.645
E50-E64 Other nutritional deficiencies	0.000	0.370	0.630
E83.4 Disorders of magnesium metabolism	0.000	0.375	0.625
E85 Amyloidosis	0.000	0.376	0.624
E84 Cystic fibrosis	0.000	0.381	0.619
E79 Disorders of purine and pyrimidine metabolism	0.000	0.381	0.619
E77 Disorders of glycoprotein metabolism	0.000	0.381	0.619
E76 Disorders of glycosaminoglycan metabolism	0.000	0.381	0.619
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.381	0.619
E74 Other disorders of carbohydrate metabolism	0.000	0.381	0.619
E72 Other disorders of amino-acid metabolism	0.000	0.381	0.619
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.381	0.619
E70 Disorders of aromatic amino-acid metabolism	0.000	0.381	0.619
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.381	0.619
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.381	0.618
E83.5 Disorders of calcium metabolism	0.000	0.390	0.610
E20-E35 Disorders of other endocrine glands	0.000	0.400	0.600
E10.1 With ketoacidosis	0.000	0.403	0.597
E10.8 With unspecified complications	0.000	0.405	0.595
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.406	0.594
E83.3 Disorders of phosphorus metabolism	0.000	0.412	0.588
E10.9 Without complications	0.000	0.433	0.567
E40-E46 Malnutrition	0.000	0.434	0.565
E87.3 Alkalosis	0.000	0.437	0.563
E88 Other metabolic disorders	0.000	0.438	0.562
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.439	0.561
E83.8 Other disorders of mineral metabolism	0.000	0.439	0.561
E83.2 Disorders of zinc metabolism	0.000	0.439	0.561
E83.0 Disorders of copper metabolism	0.000	0.439	0.561
E87.4 Mixed disorder of acid-base balance	0.000	0.443	0.556
E73.9 Lactose intolerance, unspecified	0.000	0.448	0.552
E13 Other specified diabetes mellitus	0.000	0.456	0.543
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.464	0.536
E14.7 With multiple complications	0.000	0.476	0.524
E14.6 With other specified complications	0.000	0.476	0.524
E14.5 With peripheral circulatory complications	0.000	0.476	0.524
E14.4 With neurological complications	0.000	0.476	0.524
E14.2 Withrenal complications	0.000	0.476	0.524
E14.1 With ketoacidosis	0.000	0.476	0.524
E14.0 With coma	0.000	0.476	0.524
E53 Deficiency of other B group vitamins	0.000	0.486	0.514
E21.3 Hyperparathyroidism, unspecified	0.000	0.490	0.510
E73.8 Other lactose intolerance	0.000	0.511	0.489
E73.1 Secondary lactase deficiency	0.000	0.511	0.489
E73.0 Congenital lactase deficiency	0.000	0.511	0.489
E12.9 Without complications	0.000	0.527	0.473
E12.8 With unspecified complications	0.000	0.527	0.473
E12.7 With multiple complications	0.000	0.527	0.473
E12.6 With other specified complications	0.000	0.527	0.473
E12.5 With peripheral circulatory complications	0.000	0.527	0.473
E12.4 With neurological complications	0.000	0.527	0.473
E12.3 With ophthalmic complications	0.000	0.527	0.473
E12.2 With renal complications	0.000	0.527	0.473
E12.1 With ketoacidosis	0.000	0.527	0.473
E12.0 With coma	0.000	0.527	0.473
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.533	0.467
E11.1 With ketoacidosis	0.000	0.534	0.466
E14.8 With unspecified complications	0.000	0.534	0.465
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.538	0.461
E61 Deficiency of other nutrient elements	0.000	0.547	0.453
E85.9 Amyloidosis, unspecified	0.000	0.548	0.452
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.548	0.451
E63 Other nutritional deficiencies	0.000	0.548	0.451
E56 Other vitamin deficiencies	0.000	0.548	0.451
E51 Thiamine deficiency	0.000	0.548	0.451
E50 Vitamin A deficiency	0.000	0.548	0.451
E60 Dietary zinc deficiency	0.000	0.548	0.451
E59 Dietary selenium deficiency	0.000	0.548	0.451
E58 Dietary calcium deficiency	0.000	0.548	0.451
E54 Ascorbic acid deficiency	0.000	0.548	0.451
E52 Niacin deficiency [pellagra]	0.000	0.548	0.451
E85.8 Other amyloidosis	0.000	0.553	0.447
E85.4 Organ-limited amyloidosis	0.000	0.553	0.447
E85.3 Secondary systemic amyloidosis	0.000	0.553	0.447
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.553	0.447
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.553	0.447
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.553	0.447
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.556	0.444
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.556	0.444
E70.3 Albinism	0.000	0.556	0.444
E70.2 Disorders of tyrosine metabolism	0.000	0.556	0.444
E70.1 Other hyperphenylalaninaemias	0.000	0.556	0.444
E70.0 Classical phenylketonuria	0.000	0.556	0.444
E71.3 Disorders of fatty-acid metabolism	0.000	0.556	0.444
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.556	0.444
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.556	0.444
E71.0 Maple-syrup-urine disease	0.000	0.556	0.444
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.556	0.444
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.556	0.444
E72.5 Disorders of glycine metabolism	0.000	0.556	0.444
E72.4 Disorders of ornithine metabolism	0.000	0.556	0.444
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.556	0.444
E72.2 Disorders of urea cycle metabolism	0.000	0.556	0.444
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.556	0.444
E72.0 Disorders of amino-acid transport	0.000	0.556	0.444
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.556	0.444
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.556	0.444
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.556	0.444
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.556	0.444
E74.2 Disorders of galactose metabolism	0.000	0.556	0.444
E74.1 Disorders of fructose metabolism	0.000	0.556	0.444
E74.0 Glycogen storage disease	0.000	0.556	0.444
E75.6 Lipid storage disorder, unspecified	0.000	0.556	0.444
E75.5 Other lipid storage disorders	0.000	0.556	0.444
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.556	0.444
E75.3 Sphingolipidosis, unspecified	0.000	0.556	0.444
E75.2 Other sphingolipidosis	0.000	0.556	0.444
E75.1 Other gangliosidosis	0.000	0.556	0.444
E75.0 GM2 gangliosidosis	0.000	0.556	0.444
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.556	0.444
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.556	0.444
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.556	0.444
E76.2 Other mucopolysaccharidoses	0.000	0.556	0.444
E76.1 Mucopolysaccharidosis, type II	0.000	0.556	0.444
E76.0 Mucopolysaccharidosis, type I	0.000	0.556	0.444
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.556	0.444
E77.8 Other disorders of glycoprotein metabolism	0.000	0.556	0.444
E77.1 Defects in glycoprotein degradation	0.000	0.556	0.444
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.556	0.444
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.556	0.444
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.556	0.444
E79.1 Lesch-Nyhan syndrome	0.000	0.556	0.444
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.556	0.444
E84.9 Cystic fibrosis, unspecified	0.000	0.556	0.444
E84.8 Cystic fibrosis with other manifestations	0.000	0.556	0.444
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.556	0.444
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.556	0.444
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.556	0.443
E80.6 Other disorders of bilirubin metabolism	0.000	0.556	0.443
E80.5 Crigler-Najjar syndrome	0.000	0.556	0.443
E80.3 Defects of catalase and peroxydase	0.000	0.556	0.443
E80.2 Other porphyria	0.000	0.556	0.443
E80.1 Porphyria cutanea tarda	0.000	0.556	0.443
E80.0 Hereditary erythropoietic porphyria	0.000	0.556	0.443
E80.4 Gilbert's syndrome	0.000	0.557	0.443
E27 Other disorders of adrenal gland	0.000	0.558	0.442
E34 Other endocrine disorders	0.000	0.562	0.438
E87.0 Hyperosmolality and hypernatraemia	0.000	0.565	0.435
E53.8 Deficiency of other specified B group vitamins	0.000	0.569	0.431
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.569	0.430
E32 Diseases of thymus	0.000	0.569	0.430
E31 Polyglandular dysfunction	0.000	0.569	0.430
E30 Disorders of puberty, not elsewhere classified	0.000	0.569	0.430
E25 Adrenogenital disorders	0.000	0.569	0.430
E20 Hypoparathyroidism	0.000	0.569	0.430
E15 Nondiabetic hypoglycaemic coma	0.000	0.574	0.426
E29 Testicular dysfunction	0.000	0.577	0.423
E26 Hyperaldosteronism	0.000	0.584	0.416
E24 Cushing's syndrome	0.000	0.592	0.408
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.594	0.405
E45 Retarded development following protein-energy malnutrition	0.000	0.594	0.405
E43 Unspecified severe protein-energy malnutrition	0.000	0.594	0.405
E42 Marasmic kwashiorkor	0.000	0.594	0.405
E41 Nutritional marasmus	0.000	0.594	0.405
E40 Kwashiorkor	0.000	0.594	0.405
E16 Other disorders of pancreatic internal secretion	0.000	0.597	0.403
E88.9 Metabolic disorder, unspecified	0.000	0.597	0.403
E88.8 Other specified metabolic disorders	0.000	0.597	0.403
E88.3 Tumour lysis syndrome	0.000	0.597	0.403
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.597	0.403
E28 Ovarian dysfunction	0.000	0.599	0.401
E89.2 Postprocedural hypoparathyroidism	0.000	0.601	0.399
E87.2 Acidosis	0.000	0.610	0.390
E13.8 With unspecified complications	0.000	0.610	0.390
E13.7 With multiple complications	0.000	0.610	0.390
E13.6 With other specified complications	0.000	0.610	0.390
E13.5 With peripheral circulatory complications	0.000	0.610	0.390
E13.4 With neurological complications	0.000	0.610	0.390
E13.3 With ophthalmic complications	0.000	0.610	0.390
E13.2 With renal complications	0.000	0.610	0.390
E13.1 With ketoacidosis	0.000	0.610	0.390
E13.0 With coma	0.000	0.610	0.390
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.615	0.385
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.616	0.384
E21.4 Other specified disorders of parathyroid gland	0.000	0.616	0.384
E21.2 Other hyperparathyroidism	0.000	0.616	0.384
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.616	0.384
E22 Hyperfunction of pituitary gland	0.000	0.620	0.380
E27.8 Other specified disorders of adrenal gland	0.000	0.621	0.379
E55 Vitamin D deficiency	0.000	0.627	0.373
E53.9 Vitamin B deficiency, unspecified	0.000	0.631	0.369
E53.1 Pyridoxine deficiency	0.000	0.631	0.369
E53.0 Riboflavin deficiency	0.000	0.631	0.369
E88.2 Lipomatosis, not elsewhere classified	0.000	0.632	0.367
E46 Unspecified protein-energy malnutrition	0.000	0.646	0.354
E34.9 Endocrine disorder, unspecified	0.000	0.646	0.354
E65-E68 Obesity and other hyperalimentation	0.000	0.649	0.351
E27.9 Disorder of adrenal gland, unspecified	0.000	0.660	0.340
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.665	0.335
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.665	0.335
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.665	0.335
E89.5 Postprocedural testicular hypofunction	0.000	0.665	0.335
E89.4 Postprocedural ovarian failure	0.000	0.665	0.335
E89.1 Postprocedural hypoinsulinaemia	0.000	0.665	0.335
E61.1 Iron deficiency	0.000	0.674	0.326
E61.9 Deficiency of nutrient element, unspecified	0.000	0.675	0.325
E61.8 Deficiency of other specified nutrient elements	0.000	0.675	0.325
E61.7 Deficiency of multiple nutrient elements	0.000	0.675	0.325
E61.6 Vanadium deficiency	0.000	0.675	0.325
E61.5 Molybdenum deficiency	0.000	0.675	0.325
E61.4 Chromium deficiency	0.000	0.675	0.325
E61.3 Manganese deficiency	0.000	0.675	0.325
E61.2 Magnesium deficiency	0.000	0.675	0.325
E61.0 Copper deficiency	0.000	0.675	0.325
E50.9 Vitamin A deficiency, unspecified	0.000	0.676	0.324
E50.8 Other manifestations of vitamin A deficiency	0.000	0.676	0.324
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.676	0.324
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.676	0.324
E50.5 Vitamin A deficiency with night blindness	0.000	0.676	0.324
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.676	0.324
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.676	0.324
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.676	0.324
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.676	0.324
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.676	0.324
E51.9 Thiamine deficiency, unspecified	0.000	0.676	0.324
E51.8 Other manifestations of thiamine deficiency	0.000	0.676	0.324
E51.2 Wernicke's encephalopathy	0.000	0.676	0.324
E51.1 Beriberi	0.000	0.676	0.324
E56.9 Vitamin deficiency, unspecified	0.000	0.676	0.324
E56.8 Deficiency of other vitamins	0.000	0.676	0.324
E56.1 Deficiency of vitamin K	0.000	0.676	0.324
E56.0 Deficiency of vitamin E	0.000	0.676	0.324
E63.9 Nutritional deficiency, unspecified	0.000	0.676	0.324
E63.8 Other specified nutritional deficiencies	0.000	0.676	0.324
E63.1 Imbalance of constituents of food intake	0.000	0.676	0.324
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.676	0.324
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.676	0.324
E64.8 Sequelae of other nutritional deficiencies	0.000	0.676	0.324
E64.3 Sequelae of rickets	0.000	0.676	0.324
E64.2 Sequelae of vitamin C deficiency	0.000	0.676	0.324
E64.1 Sequelae of vitamin A deficiency	0.000	0.676	0.324
E64.0 Sequelae of protein-energy malnutrition	0.000	0.676	0.324
E27.5 Adrenomedullary hyperfunction	0.000	0.683	0.317
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.683	0.317
E27.2 Addisonian crisis	0.000	0.683	0.317
E27.0 Other adrenocortical overactivity	0.000	0.683	0.317
E23 Hypofunction and other disorders of pituitary gland	0.000	0.683	0.317
E34.8 Other specified endocrine disorders	0.000	0.686	0.314
E34.5 Androgen resistance syndrome	0.000	0.686	0.314
E34.4 Constitutional tall stature	0.000	0.686	0.314
E34.3 Short stature, not elsewhere classified	0.000	0.686	0.314
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.686	0.314
E34.1 Other hypersecretion of intestinal hormones	0.000	0.686	0.314
E20.9 Hypoparathyroidism, unspecified	0.000	0.691	0.309
E20.8 Other hypoparathyroidism	0.000	0.691	0.309
E20.1 Pseudohypoparathyroidism	0.000	0.691	0.309
E20.0 Idiopathic hypoparathyroidism	0.000	0.691	0.309
E25.9 Adrenogenital disorder, unspecified	0.000	0.691	0.309
E25.8 Other adrenogenital disorders	0.000	0.691	0.309
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.691	0.309
E30.9 Disorder of puberty, unspecified	0.000	0.691	0.309
E30.8 Other disorders of puberty	0.000	0.691	0.309
E30.1 Precocious puberty	0.000	0.691	0.309
E30.0 Delayed puberty	0.000	0.691	0.309
E31.9 Polyglandular dysfunction, unspecified	0.000	0.691	0.309
E31.8 Other polyglandular dysfunction	0.000	0.691	0.309
E31.1 Polyglandular hyperfunction	0.000	0.691	0.309
E31.0 Autoimmune polyglandular failure	0.000	0.691	0.309
E32.9 Disease of thymus, unspecified	0.000	0.691	0.309
E32.8 Other diseases of thymus	0.000	0.691	0.309
E32.1 Abscess of thymus	0.000	0.691	0.309
E32.0 Persistent hyperplasia of thymus	0.000	0.691	0.309
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.691	0.309
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.691	0.309
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.691	0.309
E29.9 Testicular dysfunction, unspecified	0.000	0.696	0.304
E29.8 Other testicular dysfunction	0.000	0.696	0.304
E29.0 Testicular hyperfunction	0.000	0.696	0.304
E14.9 Without complications	0.000	0.700	0.300
E26.9 Hyperaldosteronism, unspecified	0.000	0.701	0.299
E26.8 Other hyperaldosteronism	0.000	0.701	0.299
E26.1 Secondary hyperaldosteronism	0.000	0.701	0.299
E29.1 Testicular hypofunction	0.000	0.703	0.296
E24.8 Other Cushing's syndrome	0.000	0.707	0.293
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.707	0.293
E24.3 Ectopic ACTH syndrome	0.000	0.707	0.293
E24.2 Drug-induced Cushing's syndrome	0.000	0.707	0.293
E24.1 Nelson's syndrome	0.000	0.707	0.293
E24.0 Pituitary-dependent Cushing's disease	0.000	0.707	0.293
E44.1 Mild protein-energy malnutrition	0.000	0.709	0.291
E44.0 Moderate protein-energy malnutrition	0.000	0.709	0.291
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.711	0.289
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.711	0.289
E16.4 Abnormal secretion of gastrin	0.000	0.711	0.289
E16.3 Increased secretion of glucagon	0.000	0.711	0.289
E16.1 Other hypoglycaemia	0.000	0.711	0.289
E28.9 Ovarian dysfunction, unspecified	0.000	0.712	0.287
E28.8 Other ovarian dysfunction	0.000	0.712	0.287
E28.1 Androgen excess	0.000	0.712	0.287
E28.0 Oestrogen excess	0.000	0.712	0.287
E28.3 Primary ovarian failure	0.000	0.715	0.285
E26.0 Primary hyperaldosteronism	0.000	0.715	0.284
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.721	0.278
E16.2 Hypoglycaemia, unspecified	0.000	0.722	0.278
E21.0 Primary hyperparathyroidism	0.000	0.724	0.276
E89.3 Postprocedural hypopituitarism	0.000	0.726	0.274
E22.0 Acromegaly and pituitary gigantism	0.000	0.726	0.274
E13.9 Without complications	0.001	0.726	0.273
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.728	0.272
E22.8 Other hyperfunction of pituitary gland	0.000	0.728	0.272
E24.9 Cushing's syndrome, unspecified	0.000	0.730	0.270
E55.0 Rickets, active	0.000	0.732	0.268
E34.0 Carcinoid syndrome	0.000	0.734	0.266
E27.1 Primary adrenocortical insufficiency	0.000	0.737	0.263
E28.2 Polycystic ovarian syndrome	0.000	0.740	0.260
E67 Other hyperalimentation	0.000	0.748	0.252
E68 Sequelae of hyperalimentation	0.000	0.748	0.252
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.749	0.251
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.750	0.250
E22.1 Hyperprolactinaemia	0.000	0.753	0.246
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.758	0.242
E23.2 Diabetes insipidus	0.000	0.768	0.232
E23.7 Disorder of pituitary gland, unspecified	0.000	0.773	0.227
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.773	0.227
E23.1 Drug-induced hypopituitarism	0.000	0.773	0.227
E65 Localised adiposity	0.000	0.775	0.225
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.783	0.217
E78.4 Other hyperlipidaemia	0.000	0.799	0.201
E23.6 Other disorders of pituitary gland	0.000	0.800	0.199
E00-E07 Disorders of thyroid gland	0.000	0.807	0.193
E55.9 Vitamin D deficiency, unspecified	0.000	0.810	0.189
E67.8 Other specified hyperalimentation	0.000	0.819	0.180
E67.3 Hypervitaminosis D	0.000	0.819	0.180
E67.2 Megavitamin-B6 syndrome	0.000	0.819	0.180
E67.1 Hypercarotenaemia	0.000	0.819	0.180
E67.0 Hypervitaminosis A	0.000	0.819	0.180
E78.6 Lipoprotein deficiency	0.000	0.826	0.174
E78.3 Hyperchylomicronaemia	0.000	0.826	0.174
E78.8 Other disorders of lipoprotein metabolism	0.000	0.829	0.171
E23.0 Hypopituitarism	0.000	0.848	0.152
E78.1 Pure hyperglyceridaemia	0.000	0.858	0.142
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.861	0.139
E00 Congenital iodine-deficiency syndrome	0.000	0.861	0.139
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.861	0.139
E07 Other disorders of thyroid	0.000	0.865	0.135
E04 Other non-toxic goitre	0.000	0.867	0.132
E04.2 Non-toxic multinodular goitre	0.000	0.876	0.124
E78.2 Mixed hyperlipidaemia	0.000	0.883	0.117
E06 Thyroiditis	0.000	0.891	0.108
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.900	0.100
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.900	0.099
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.900	0.099
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.900	0.099
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.900	0.099
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.900	0.099
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.900	0.099
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.900	0.099
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.900	0.099
E07.1 Dyshormogenetic goitre	0.000	0.903	0.097
E07.0 Hypersecretion of calcitonin	0.000	0.903	0.097
E07.9 Disorder of thyroid, unspecified	0.000	0.903	0.097
E04.8 Other specified non-toxic goitre	0.000	0.905	0.095
E07.8 Other specified disorders of thyroid	0.000	0.907	0.093
E89.0 Postprocedural hypothyroidism	0.000	0.913	0.087
E04.0 Non-toxic diffuse goitre	0.000	0.913	0.087
E04.9 Non-toxic goitre, unspecified	0.000	0.919	0.081
E06.5 Other chronic thyroiditis	0.000	0.922	0.078
E06.4 Drug-induced thyroiditis	0.000	0.922	0.078
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.922	0.078
E06.1 Subacute thyroiditis	0.000	0.922	0.078
E06.0 Acute thyroiditis	0.000	0.922	0.078
E05.8 Other thyrotoxicosis	0.000	0.928	0.072
E05.5 Thyroid crisis or storm	0.000	0.928	0.072
E05.4 Thyrotoxicosis factitia	0.000	0.928	0.072
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.928	0.072
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.928	0.072
E06.9 Thyroiditis, unspecified	0.000	0.929	0.071
E05.9 Thyrotoxicosis, unspecified	0.000	0.936	0.064
E66 Obesity	0.000	0.937	0.063
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.938	0.062
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.938	0.062
E06.3 Autoimmune thyroiditis	0.000	0.941	0.059
H36.0 Diabetic retinopathy	0.000	0.951	0.049
E87.1 Hypo-osmolality and hyponatraemia	0.001	0.953	0.046
E66.1 Drug-induced obesity	0.000	0.955	0.045
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.957	0.043
E03 Other hypothyroidism	0.000	0.958	0.042
E66.0 Obesity due to excess calories	0.000	0.966	0.034
E78.0 Pure hypercholesterolaemia	0.000	0.968	0.032
E03.5 Myxoedema coma	0.000	0.970	0.030
E03.4 Atrophy of thyroid (acquired)	0.000	0.970	0.030
E03.3 Postinfectious hypothyroidism	0.000	0.970	0.030
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.970	0.030
E66.8 Other obesity	0.000	0.970	0.030
E03.8 Other specified hypothyroidism	0.000	0.973	0.026
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.973	0.026
E03.1 Congenital hypothyroidism without goitre	0.000	0.976	0.023
E04.1 Non-toxic single thyroid nodule	0.002	0.978	0.019
H36 Retinal disorders in diseases classified elsewhere	0.000	0.979	0.021
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.985	0.015
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.015	0.985	0.000
I95.9 Hypotension, unspecified	0.000	0.987	0.013
N18.9 Chronic renal failure, unspecified	0.000	0.988	0.012
N18 Chronic renal failure	0.000	0.991	0.009
N18.5 Chronic kidney disease, stage 5	0.000	0.991	0.009
N18.0 End-stage renal disease	0.000	0.992	0.008
M67.8 Other specified disorders of synovium and tendon	0.008	0.992	0.000
Z01.6 Radiological examination, not elsewhere classified	0.007	0.993	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.007	0.993	0.000
N18.8 Other chronic renal failure	0.000	0.993	0.006
N18.1 Chronic kidney disease, stage 1	0.000	0.993	0.006
N18.4 Chronic kidney disease, stage 4	0.000	0.993	0.006
H57.8 Other specified disorders of eye and adnexa	0.006	0.994	0.000
N18.2 Chronic kidney disease, stage 2	0.000	0.994	0.006
E78.5 Hyperlipidaemia, unspecified	0.000	0.994	0.005
K55.2 Angiodysplasia of colon	0.000	0.995	0.005
Z88.5 Personal history of allergy to narcotic agent	0.005	0.995	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.005	0.995	0.000
Z09.2 Follow-up examination after chemotherapy for other conditions	0.005	0.995	0.000
A41.9 Septicaemia, unspecified	0.000	0.995	0.005
O69.1 Labour and delivery complicated by cord around neck, with compression	0.005	0.995	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.004	0.995	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.996	0.004
M87.9 Osteonecrosis, unspecified	0.004	0.996	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.004	0.996	0.000
K55 Vascular disorders of intestine	0.000	0.996	0.004
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.996	0.004
M79.62 Pain in limb (Upper arm)	0.000	0.996	0.004
K55.9 Vascular disorder of intestine, unspecified	0.000	0.996	0.004
S30.1 Contusion of abdominal wall	0.004	0.996	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.004	0.996	0.000
K55.0 Acute vascular disorders of intestine	0.000	0.996	0.004
H57 Other disorders of eye and adnexa	0.004	0.996	0.000
O42.9 Premature rupture of membranes, unspecified	0.003	0.997	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.997	0.003
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.003	0.997	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.003	0.997	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.003	0.997	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.003	0.997	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.003	0.997	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.003	0.997	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.003	0.997	0.000
O42 Premature rupture of membranes	0.003	0.997	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.003	0.997	0.000
S30.0 Contusion of lower back and pelvis	0.003	0.997	0.000
M67 Other disorders of synovium and tendon	0.003	0.997	0.000
J98.8 Other specified respiratory disorders	0.000	0.997	0.003
S30.2 Contusion of external genital organs	0.003	0.997	0.000
H57.0 Anomalies of pupillary function	0.003	0.997	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.997	0.003
J98.4 Other disorders of lung	0.000	0.997	0.003
H33.0 Retinal detachment with retinal break	0.003	0.997	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.997	0.003
K55.1 Chronic vascular disorders of intestine	0.000	0.997	0.003
N17-N19 Renal failure	0.000	0.997	0.003
H65.3 Chronic mucoid otitis media	0.000	0.997	0.003
M79.65 Pain in limb (Pelvic region and thigh)	0.000	0.997	0.003
Q82.5 Congenital nonneoplastic naevus	0.003	0.997	0.000
F03 Unspecified dementia	0.000	0.997	0.003
K55.8 Other vascular disorders of intestine	0.000	0.997	0.003
M67.4 Ganglion	0.003	0.997	0.000
M79.67 Pain in limb (Ankle and foot)	0.000	0.997	0.003
J84 Other interstitial pulmonary diseases	0.000	0.997	0.003
M79.6 Pain in limb	0.000	0.997	0.003
O42.2 Premature rupture of membranes, labour delayed by therapy	0.003	0.997	0.000
M87 Osteonecrosis	0.003	0.997	0.000
F01.9 Vascular dementia, unspecified	0.000	0.997	0.003
J98 Other respiratory disorders	0.000	0.997	0.003
M67.9 Disorder of synovium and tendon, unspecified	0.002	0.997	0.000
M67.3 Transient synovitis	0.002	0.997	0.000
M67.0 Short Achilles tendon (acquired)	0.002	0.997	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.997	0.003
F00 Dementia in Alzheimer's disease	0.000	0.997	0.003
N17 Acute renal failure	0.000	0.997	0.003
Z99.2 Dependence on renal dialysis	0.000	0.997	0.003
M79.61 Pain in limb (Shoulder region)	0.000	0.997	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations