TreeWAS – Variant ID: rs17143755

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
M80-M85 Disorders of bone density and structure	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter V Mental and behavioural disorders	0.998	0.002
M81 Osteoporosis without pathological fracture	0.996	0.004
Chapter II Neoplasms	0.993	0.007
M20-M25 Other joint disorders	0.993	0.007
F30-F39 Mood [affective] disorders	0.992	0.008
M81.9 Osteoporosis, unspecified	0.991	0.009
M20 Acquired deformities of fingers and toes	0.987	0.013
M81.99 Osteoporosis, unspecified (Site unspecified)	0.983	0.017
F31 Bipolar affective disorder	0.982	0.018
M20.4 Other hammer toe(s) (acquired)	0.973	0.027
C15-C26 Malignant neoplasms of digestive organs	0.969	0.031
Chapter VI Diseases of the nervous system	0.969	0.031
M80 Osteoporosis with pathological fracture	0.966	0.034
G20-G26 Extrapyramidal and movement disorders	0.952	0.048
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.952	0.048
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.946	0.054
Chapter VIII Diseases of the ear and mastoid process	0.946	0.054
G20 Parkinson's disease	0.945	0.055
M84 Disorders of continuity of bone	0.943	0.057
M20.6 Acquired deformity of toe(s), unspecified	0.942	0.058
C43-C44 Melanoma and other malignant neoplasms of skin	0.942	0.058
F31.9 Bipolar affective disorder, unspecified	0.940	0.060
D37-D48 Neoplasms of uncertain or unknown behaviour	0.930	0.070
S20-S29 Injuries to the thorax	0.922	0.078
M24 Other specific joint derangements	0.922	0.078
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.922	0.078
T51 Toxic effect of alcohol	0.918	0.082
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.911	0.089
C34 Malignant neoplasm of bronchus and lung	0.910	0.090
C18 Malignant neoplasm of colon	0.907	0.093
C44 Other malignant neoplasms of skin	0.906	0.094
S60-S69 Injuries to the wrist and hand	0.904	0.096
F33 Recurrent depressive disorder	0.903	0.097
C15 Malignant neoplasm of oesophagus	0.903	0.097
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.902	0.098
T20-T25 Burns and corrosions of external body surface, specified by site	0.898	0.102
T51.0 Ethanol	0.897	0.103
H60-H62 Diseases of external ear	0.895	0.105
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.892	0.108
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.888	0.112
M86-M90 Other osteopathies	0.886	0.114
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.885	0.115
C18.9 Colon, unspecified	0.884	0.116
C17 Malignant neoplasm of small intestine	0.883	0.117
M25 Other joint disorders, not elsewhere classified	0.882	0.118
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.881	0.119
M81.90 Osteoporosis, unspecified (Multiple sites)	0.876	0.124
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.875	0.125
F40-F48 Neurotic, stress-related and somatoform disorders	0.869	0.131
S10-S19 Injuries to the neck	0.869	0.131
T36-T50 Poisoning by drugs, medicaments and biological substances	0.865	0.135
C44.7 Skin of lower limb, including hip	0.865	0.135
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.864	0.136
C44.6 Skin of upper limb, including shoulder	0.863	0.137
M80.9 Unspecified osteoporosis with pathological fracture	0.862	0.138
Chapter XX External causes of morbidity and mortality	0.862	0.138
H60 Otitis externa	0.862	0.138
M84.1 Nonunion of fracture [pseudarthrosis]	0.862	0.138
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.859	0.141
C71 Malignant neoplasm of brain	0.858	0.142
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.858	0.142
M25.5 Pain in joint	0.855	0.145
S50-S59 Injuries to the elbow and forearm	0.852	0.148
Chapter XXII Codes for special purposes	0.851	0.149
M25.56 Pain in joint (Lower leg)	0.848	0.152
H65-H75 Diseases of middle ear and mastoid	0.847	0.153
C15.5 Lower third of oesophagus	0.846	0.154
G70-G73 Diseases of myoneural junction and muscle	0.844	0.156
D41.0 Kidney	0.842	0.158
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.839	0.161
G90-G99 Other disorders of the nervous system	0.839	0.161
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.839	0.161
M31 Other necrotising vasculopathies	0.837	0.163
S22 Fracture of rib(s), sternum and thoracic spine	0.836	0.164
C34.9 Bronchus or lung, unspecified	0.836	0.164
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.832	0.168
M81.2 Osteoporosis of disuse	0.832	0.168
S64 Injury of nerves at wrist and hand level	0.823	0.177
T92 Sequelae of injuries of upper limb	0.822	0.178
H72 Perforation of tympanic membrane	0.820	0.180
Q20-Q28 Congenital malformations of the circulatory system	0.814	0.186
G80-G83 Cerebral palsy and other paralytic syndromes	0.814	0.186
C73 Malignant neoplasm of thyroid gland	0.813	0.187
M65-M68 Disorders of synovium and tendon	0.811	0.189
S61 Open wound of wrist and hand	0.810	0.190
S69 Other and unspecified injuries of wrist and hand	0.808	0.192
M50-M54 Other dorsopathies	0.806	0.194
W00-W19 Falls	0.803	0.197
C34.0 Main bronchus	0.802	0.198
S32 Fracture of lumbar spine and pelvis	0.801	0.199
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.801	0.199
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.799	0.201
S90-S99 Injuries to the ankle and foot	0.799	0.201
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.795	0.205
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.794	0.206
C44.2 Skin of ear and external auricular canal	0.793	0.207
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.792	0.208
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.788	0.212
M24.1 Other articular cartilage disorders	0.788	0.212
C26 Malignant neoplasm of other and ill-defined digestive organs	0.787	0.213
F43 Reaction to severe stress, and adjustment disorders	0.786	0.214
T14 Injury of unspecified body region	0.784	0.216
S22.3 Fracture of rib	0.782	0.218
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.782	0.218
C71.1 Frontal lobe	0.781	0.218
S61.0 Open wound of finger(s) without damage to nail	0.781	0.219
C17.0 Duodenum	0.780	0.220
M85 Other disorders of bone density and structure	0.779	0.220
Chapter XII Diseases of the skin and subcutaneous tissue	0.778	0.222
G62 Other polyneuropathies	0.772	0.228
H72.0 Central perforation of tympanic membrane	0.772	0.228
C19 Malignant neoplasm of rectosigmoid junction	0.770	0.230
C18.6 Descending colon	0.768	0.232
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.766	0.234
M89 Other disorders of bone	0.765	0.235
M84.0 Malunion of fracture	0.765	0.235
F25 Schizoaffective disorders	0.763	0.237
M15-M19 Arthrosis	0.761	0.239
T20 Burn and corrosion of head and neck	0.760	0.240
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.760	0.240
T79-T79 Certain early complications of trauma	0.760	0.240
T00-T07 Injuries involving multiple body regions	0.758	0.241
M40-M43 Deforming dorsopathies	0.758	0.242
M35 Other systemic involvement of connective tissue	0.758	0.242
M80.5 Idiopathic osteoporosis with pathological fracture	0.757	0.243
V10-V19 Pedal cyclist injured in transport accident	0.757	0.243
C40-C41 Malignant neoplasms of bone and articular cartilage	0.756	0.244
M91-M94 Chondropathies	0.755	0.244
F40 Phobic anxiety disorders	0.753	0.247
F30 Manic episode	0.752	0.248
F60-F69 Disorders of adult personality and behaviour	0.749	0.251
M80.8 Other osteoporosis with pathological fracture	0.749	0.251
C79 Secondary malignant neoplasm of other sites	0.749	0.251
H65 Nonsuppurative otitis media	0.748	0.252
C18.0 Caecum	0.748	0.252
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.747	0.253
C18.8 Overlapping lesion of colon	0.746	0.254
M25.53 Pain in joint (Forearm)	0.746	0.254
F31.0 Bipolar affective disorder, current episode hypomanic	0.745	0.255
M84.4 Pathological fracture, not elsewhere classified	0.745	0.255
S22.30 Fracture of rib (closed)	0.743	0.257
F43.2 Adjustment disorders	0.740	0.260
S27 Injury of other and unspecified intrathoracic organs	0.739	0.261
D37.5 Rectum	0.739	0.261
L20-L30 Dermatitis and eczema	0.739	0.261
M80.0 Postmenopausal osteoporosis with pathological fracture	0.736	0.264
C30 Malignant neoplasm of nasal cavity and middle ear	0.734	0.266
F39 Unspecified mood [affective] disorder	0.734	0.266
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.732	0.268
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.732	0.268
C71.3 Parietal lobe	0.732	0.268
T23 Burn and corrosion of wrist and hand	0.731	0.268
M34 Systemic sclerosis	0.731	0.269
M60-M63 Disorders of muscles	0.729	0.271
C15.9 Oesophagus, unspecified	0.728	0.272
M81.98 Osteoporosis, unspecified (Other)	0.728	0.272
M25.6 Stiffness of joint, not elsewhere classified	0.728	0.272
H72.9 Perforation of tympanic membrane, unspecified	0.727	0.273
F80-F89 Disorders of psychological development	0.727	0.273
H60.1 Cellulitis of external ear	0.727	0.273
F33.9 Recurrent depressive disorder, unspecified	0.725	0.275
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.725	0.275
D37.0 Lip, oral cavity and pharynx	0.724	0.276
M20.2 Hallux rigidus	0.722	0.278
M24.2 Disorder of ligament	0.722	0.278
C17.9 Small intestine, unspecified	0.721	0.279
M24.0 Loose body in joint	0.721	0.279
L30 Other dermatitis	0.719	0.281
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M83 Adult osteomalacia	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
S64.4 Injury of digital nerve of other finger	0.716	0.284
M24.16 Other articular cartilage disorders (Lower leg)	0.716	0.284
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.715	0.284
F70-F79 Mental retardation	0.715	0.284
C32 Malignant neoplasm of larynx	0.715	0.285
M81.8 Other osteoporosis	0.714	0.286
M81.6 Localised osteoporosis [Lequesne]	0.714	0.286
M81.5 Idiopathic osteoporosis	0.714	0.286
M81.3 Postsurgical malabsorption osteoporosis	0.714	0.286
M81.1 Postoophorectomy osteoporosis	0.714	0.286
M81.0 Postmenopausal osteoporosis	0.714	0.286
M81.20 Osteoporosis of disuse (Multiple sites)	0.714	0.286
G72 Other myopathies	0.713	0.286
H60.3 Other infective otitis externa	0.712	0.288
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.712	0.288
M33 Dermatopolymyositis	0.712	0.288
M32 Systemic lupus erythematosus	0.712	0.288
M24.6 Ankylosis of joint	0.712	0.288
F38 Other mood [affective] disorders	0.711	0.289
F34 Persistent mood [affective] disorders	0.711	0.289
M81.4 Drug-induced osteoporosis	0.711	0.289
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.711	0.289
M81.96 Osteoporosis, unspecified (Lower leg)	0.711	0.289
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.711	0.289
M81.94 Osteoporosis, unspecified (Hand)	0.711	0.289
M81.93 Osteoporosis, unspecified (Forearm)	0.711	0.289
M81.92 Osteoporosis, unspecified (Upper arm)	0.711	0.289
M81.91 Osteoporosis, unspecified (Shoulder region)	0.711	0.289
F29 Unspecified nonorganic psychosis	0.710	0.290
Q23 Congenital malformations of aortic and mitral valves	0.710	0.290
S21 Open wound of thorax	0.710	0.290
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.709	0.290
M16 Coxarthrosis [arthrosis of hip]	0.709	0.291
L30.9 Dermatitis, unspecified	0.708	0.292
M24.5 Contracture of joint	0.708	0.292
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.707	0.293
T11 Other injuries of upper limb, level unspecified	0.707	0.293
M16.1 Other primary coxarthrosis	0.707	0.293
S50 Superficial injury of forearm	0.706	0.294
T09 Other injuries of spine and trunk, level unspecified	0.706	0.294
G82 Paraplegia and tetraplegia	0.705	0.295
T56 Toxic effect of metals	0.705	0.295
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.704	0.295
F31.8 Other bipolar affective disorders	0.704	0.296
F31.7 Bipolar affective disorder, currently in remission	0.704	0.296
F31.6 Bipolar affective disorder, current episode mixed	0.704	0.296
M90 Osteopathies in diseases classified elsewhere	0.703	0.297
M31.6 Other giant cell arteritis	0.702	0.298
G00-G09 Inflammatory diseases of the central nervous system	0.701	0.299
M82 Osteoporosis in diseases classified elsewhere	0.701	0.299
S37 Injury of urinary and pelvic organs	0.699	0.300
M25.52 Pain in joint (Upper arm)	0.699	0.301
M25.57 Pain in joint (Ankle and foot)	0.698	0.302
C44.5 Skin of trunk	0.698	0.302
S69.9 Unspecified injury of wrist and hand	0.697	0.303
W50-W64 Exposure to animate mechanical forces	0.697	0.303
T92.2 Sequelae of fracture at wrist and hand level	0.696	0.304
M25.3 Other instability of joint	0.696	0.304
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.695	0.305
C23 Malignant neoplasm of gallbladder	0.695	0.305
H60.0 Abscess of external ear	0.695	0.305
M54 Dorsalgia	0.694	0.306
S22.5 Flail chest	0.694	0.306
T92.0 Sequelae of open wound of upper limb	0.693	0.306
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.693	0.307
M65 Synovitis and tenosynovitis	0.693	0.307
F22 Persistent delusional disorders	0.693	0.307
M80.4 Drug-induced osteoporosis with pathological fracture	0.692	0.308
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.692	0.308
M80.2 Osteoporosis of disuse with pathological fracture	0.692	0.308
S30 Superficial injury of abdomen, lower back and pelvis	0.691	0.309
D37.9 Digestive organ, unspecified	0.690	0.310
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.690	0.310
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.689	0.311
G62.8 Other specified polyneuropathies	0.689	0.311
M20.5 Other deformities of toe(s) (acquired)	0.689	0.311
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.688	0.311
C34.1 Upper lobe, bronchus or lung	0.688	0.312
H60.8 Other otitis externa	0.688	0.312
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.687	0.313
W18 Other fall on same level	0.686	0.314
S65 Injury of blood vessels at wrist and hand level	0.686	0.314
M30 Polyarteritis nodosa and related conditions	0.685	0.315
S32.3 Fracture of ilium	0.684	0.316
C51-C58 Malignant neoplasms of female genital organs	0.684	0.316
G95 Other diseases of spinal cord	0.683	0.317
G23 Other degenerative diseases of basal ganglia	0.683	0.317
G21 Secondary Parkinsonism	0.683	0.317
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.683	0.317
G22 Parkinsonism in diseases classified elsewhere	0.683	0.317
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.682	0.318
C38 Malignant neoplasm of heart, mediastinum and pleura	0.682	0.318
C31 Malignant neoplasm of accessory sinuses	0.682	0.318
C37 Malignant neoplasm of thymus	0.682	0.318
C33 Malignant neoplasm of trachea	0.682	0.318
F33.1 Recurrent depressive disorder, current episode moderate	0.682	0.318
H60.5 Acute otitis externa, non-infective	0.682	0.318
Q80-Q89 Other congenital malformations	0.681	0.319
G94 Other disorders of brain in diseases classified elsewhere	0.680	0.320
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.680	0.320
T65 Toxic effect of other and unspecified substances	0.678	0.321
T62 Toxic effect of other noxious substances eaten as food	0.678	0.321
T61 Toxic effect of noxious substances eaten as seafood	0.678	0.321
T60 Toxic effect of pesticides	0.678	0.321
T57 Toxic effect of other inorganic substances	0.678	0.321
T54 Toxic effect of corrosive substances	0.678	0.321
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.678	0.321
T52 Toxic effect of organic solvents	0.678	0.321
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.678	0.321
T55 Toxic effect of soaps and detergents	0.678	0.321
S64.2 Injury of radial nerve at wrist and hand level	0.678	0.322
V70-V79 Bus occupant injured in transport accident	0.678	0.322
T91 Sequelae of injuries of neck and trunk	0.677	0.322
H65.4 Other chronic nonsuppurative otitis media	0.677	0.323
M86 Osteomyelitis	0.676	0.324
M84.9 Disorder of continuity of bone, unspecified	0.676	0.324
M84.8 Other disorders of continuity of bone	0.676	0.324
M84.3 Stress fracture, not elsewhere classified	0.676	0.324
M84.2 Delayed union of fracture	0.676	0.324
S13.4 Sprain and strain of cervical spine	0.676	0.324
V20-V29 Motorcycle rider injured in transport accident	0.675	0.325
D37.6 Liver, gallbladder and bile ducts	0.675	0.325
T14.0 Superficial injury of unspecified body region	0.674	0.326
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.673	0.327
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.673	0.327
G71 Primary disorders of muscles	0.673	0.327
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.672	0.328
C43 Malignant melanoma of skin	0.671	0.329
F20 Schizophrenia	0.670	0.330
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.669	0.331
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.669	0.331
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.667	0.333
M24.4 Recurrent dislocation and subluxation of joint	0.667	0.333
S69.8 Other specified injuries of wrist and hand	0.667	0.333
H60.9 Otitis externa, unspecified	0.666	0.334
T90 Sequelae of injuries of head	0.666	0.334
X10-X19 Contact with heat and hot substances	0.665	0.335
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.663	0.337
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.662	0.337
C34.3 Lower lobe, bronchus or lung	0.662	0.338
T20.1 Burn of first degree of head and neck	0.662	0.338
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.661	0.338
V18 Pedal cyclist injured in noncollision transport accident	0.661	0.339
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.661	0.339
S26 Injury of heart	0.661	0.339
S25 Injury of blood vessels of thorax	0.661	0.339
S24 Injury of nerves and spinal cord at thorax level	0.661	0.339
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.661	0.339
M24.9 Joint derangement, unspecified	0.661	0.339
M24.8 Other specific joint derangements, not elsewhere classified	0.661	0.339
M24.7 Protrusio acetabuli	0.661	0.339
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.661	0.339
F40.2 Specific (isolated) phobias	0.661	0.339
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.661	0.339
S36 Injury of intra-abdominal organs	0.661	0.339
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.661	0.339
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.661	0.339
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.661	0.339
S31 Open wound of abdomen, lower back and pelvis	0.661	0.339
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.661	0.339
M20.3 Other deformity of hallux (acquired)	0.660	0.340
Q00-Q07 Congenital malformations of the nervous system	0.659	0.341
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.659	0.341
M00-M03 Infectious arthropathies	0.658	0.342
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.658	0.342
T51.8 Other alcohols	0.658	0.342
T51.3 Fusel oil	0.658	0.342
T51.2 2-Propanol	0.658	0.342
T51.1 Methanol	0.658	0.342
D44.8 Pluriglandular involvement	0.656	0.344
T51.9 Alcohol, unspecified	0.656	0.344
C26.0 Intestinal tract, part unspecified	0.656	0.344
V01-V09 Pedestrian injured in transport accident	0.656	0.344
T63 Toxic effect of contact with venomous animals	0.655	0.344
L60-L75 Disorders of skin appendages	0.655	0.345
M25.8 Other specified joint disorders	0.655	0.345
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.655	0.345
M84.01 Malunion of fracture (Shoulder region)	0.654	0.346
G24 Dystonia	0.654	0.346
G83 Other paralytic syndromes	0.653	0.347
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.653	0.347
C70 Malignant neoplasm of meninges	0.653	0.347
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.653	0.347
S51 Open wound of forearm	0.653	0.347
D41.4 Bladder	0.653	0.347
T46 Poisoning by agents primarily affecting the cardiovascular system	0.653	0.347
W10 Fall on and from stairs and steps	0.652	0.348
C34.8 Overlapping lesion of bronchus and lung	0.652	0.348
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.651	0.348
M88 Paget's disease of bone [osteitis deformans]	0.651	0.349
C17.2 Ileum	0.651	0.349
S12 Fracture of neck	0.650	0.350
C44.8 Overlapping lesion of skin	0.649	0.350
M45-M49 Spondylopathies	0.649	0.351
Q24 Other congenital malformations of heart	0.649	0.351
L50-L54 Urticaria and erythema	0.649	0.351
F33.8 Other recurrent depressive disorders	0.648	0.352
F33.4 Recurrent depressive disorder, currently in remission	0.648	0.352
F33.0 Recurrent depressive disorder, current episode mild	0.648	0.352
C18.1 Appendix	0.647	0.352
M50 Cervical disk disorders	0.648	0.352
C15.8 Overlapping lesion of oesophagus	0.647	0.353
C15.3 Upper third of oesophagus	0.647	0.353
C15.2 Abdominal part of oesophagus	0.647	0.353
C15.1 Thoracic part of oesophagus	0.647	0.353
C15.0 Cervical part of oesophagus	0.647	0.353
S29 Other and unspecified injuries of thorax	0.647	0.353
T13 Other injuries of lower limb, level unspecified	0.647	0.353
T12.X1 Fracture of lower limb, level unspecified (open)	0.647	0.353
T12.X0 Fracture of lower limb, level unspecified (closed)	0.647	0.353
T12 Fracture of lower limb, level unspecified	0.647	0.353
T10.X1 Fracture of upper limb, level unspecified (open)	0.647	0.353
T10.X0 Fracture of upper limb, level unspecified (closed)	0.647	0.353
T10 Fracture of upper limb, level unspecified	0.647	0.353
T08.X1 Fracture of spine, level unspecified (open)	0.647	0.353
T08.X0 Fracture of spine, level unspecified (closed)	0.647	0.353
T08 Fracture of spine, level unspecified	0.647	0.353
S92 Fracture of foot, except ankle	0.646	0.354
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.646	0.354
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.645	0.355
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.644	0.356
T25 Burn and corrosion of ankle and foot	0.643	0.356
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.643	0.356
T21 Burn and corrosion of trunk	0.643	0.356
T59 Toxic effect of other gases, fumes and vapours	0.642	0.357
S52 Fracture of forearm	0.643	0.357
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.642	0.357
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.642	0.358
H62 Disorders of external ear in diseases classified elsewhere	0.642	0.358
V80-V89 Other land transport accidents	0.642	0.358
G62.9 Polyneuropathy, unspecified	0.641	0.359
S64.1 Injury of median nerve at wrist and hand level	0.640	0.360
Q27 Other congenital malformations of peripheral vascular system	0.640	0.360
C51 Malignant neoplasm of vulva	0.639	0.361
M65.3 Trigger finger	0.639	0.361
F28 Other nonorganic psychotic disorders	0.639	0.361
F24 Induced delusional disorder	0.639	0.361
F21 Schizotypal disorder	0.639	0.361
S20 Superficial injury of thorax	0.639	0.361
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.638	0.362
W05 Fall involving wheelchair	0.638	0.362
D46 Myelodysplastic syndromes	0.637	0.363
H65.9 Nonsuppurative otitis media, unspecified	0.637	0.363
C75 Malignant neoplasm of other endocrine glands and related structures	0.637	0.363
C74 Malignant neoplasm of adrenal gland	0.637	0.363
Q38-Q45 Other congenital malformations of the digestive system	0.636	0.363
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.636	0.364
Q25 Congenital malformations of great arteries	0.635	0.365
T98 Sequelae of other and unspecified effects of external causes	0.634	0.365
T95 Sequelae of burns, corrosions and frostbite	0.634	0.365
T94 Sequelae of injuries involving multiple and unspecified body regions	0.634	0.365
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.634	0.365
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.634	0.365
G96 Other disorders of central nervous system	0.634	0.366
M25.58 Pain in joint (Other)	0.634	0.366
C17.8 Overlapping lesion of small intestine	0.633	0.367
C17.3 Meckel's diverticulum	0.633	0.367
C17.1 Jejunum	0.633	0.367
T15-T19 Effects of foreign body entering through natural orifice	0.633	0.367
M25.2 Flail joint	0.633	0.367
M25.1 Fistula of joint	0.633	0.367
S32.7 Multiple fractures of lumbar spine and pelvis	0.633	0.367
V40-V49 Car occupant injured in transport accident	0.632	0.368
M96.0 Pseudarthrosis after fusion or arthrodesis	0.632	0.368
D41.9 Urinary organ, unspecified	0.631	0.368
D41.7 Other urinary organs	0.631	0.368
D41.3 Urethra	0.631	0.368
D41.2 Ureter	0.631	0.368
D41.1 Renal pelvis	0.631	0.368
H70 Mastoiditis and related conditions	0.631	0.369
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.631	0.369
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.631	0.369
F48 Other neurotic disorders	0.631	0.369
M54.1 Radiculopathy	0.630	0.370
W07 Fall involving chair	0.629	0.371
T58 Toxic effect of carbon monoxide	0.628	0.372
M20.1 Hallux valgus (acquired)	0.628	0.372
S32.0 Fracture of lumbar vertebra	0.628	0.372
C71.9 Brain, unspecified	0.628	0.372
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.627	0.373
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.627	0.373
Q35-Q37 Cleft lip and cleft palate	0.627	0.373
Q30-Q34 Congenital malformations of the respiratory system	0.627	0.373
H90-H95 Other disorders of ear	0.627	0.373
C79.2 Secondary malignant neoplasm of skin	0.627	0.373
S32.1 Fracture of sacrum	0.626	0.374
C44.9 Malignant neoplasm of skin, unspecified	0.626	0.374
S10 Superficial injury of neck	0.626	0.374
G91 Hydrocephalus	0.626	0.374
T92.8 Sequelae of other specified injuries of upper limb	0.625	0.375
M85.6 Other cyst of bone	0.624	0.376
C69 Malignant neoplasm of eye and adnexa	0.623	0.377
M25.59 Pain in joint (Site unspecified)	0.623	0.377
F44 Dissociative [conversion] disorders	0.623	0.377
S17 Crushing injury of neck	0.623	0.377
S15 Injury of blood vessels at neck level	0.623	0.377
S14 Injury of nerves and spinal cord at neck level	0.623	0.377
S11 Open wound of neck	0.623	0.377
S18 Traumatic amputation at neck level	0.623	0.377
S16 Injury of muscle and tendon at neck level	0.623	0.377
F12 Mental and behavioural disorders due to use of cannabinoids	0.623	0.377
G95.8 Other specified diseases of spinal cord	0.622	0.378
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.621	0.378
M54.3 Sciatica	0.622	0.378
M24.11 Other articular cartilage disorders (Shoulder region)	0.621	0.378
T36 Poisoning by systemic antibiotics	0.620	0.380
H66 Suppurative and unspecified otitis media	0.620	0.380
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.620	0.380
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.620	0.380
T41 Poisoning by anaesthetics and therapeutic gases	0.620	0.380
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.620	0.380
D37.3 Appendix	0.619	0.381
D37.2 Small intestine	0.619	0.381
M89.8 Other specified disorders of bone	0.619	0.381
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.619	0.381
Y00-Y09 Assault	0.618	0.382
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.618	0.382
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.618	0.382
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.618	0.382
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.618	0.382
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.618	0.382
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.618	0.382
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.618	0.382
Y35-Y36 Legal intervention and operations of war	0.618	0.382

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations