TreeWAS – Variant ID: rs17183114

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R59.0 Localised enlarged lymph nodes	0.000	0.981	0.019
R59.1 Generalised enlarged lymph nodes	0.000	0.982	0.018
E23.0 Hypopituitarism	0.000	0.982	0.018
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.983	0.017
R59 Enlarged lymph nodes	0.000	0.984	0.016
M67.8 Other specified disorders of synovium and tendon	0.015	0.985	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.987	0.013
E23.2 Diabetes insipidus	0.000	0.989	0.011
E23.6 Other disorders of pituitary gland	0.000	0.989	0.011
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.990	0.010
E23.1 Drug-induced hypopituitarism	0.000	0.990	0.010
E23.7 Disorder of pituitary gland, unspecified	0.000	0.990	0.010
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.991	0.009
E27.1 Primary adrenocortical insufficiency	0.000	0.991	0.009
E27 Other disorders of adrenal gland	0.000	0.992	0.008
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.992	0.008
D22 Melanocytic naevi	0.000	0.992	0.008
D22.4 Melanocytic naevi of scalp and neck	0.000	0.992	0.008
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.992	0.008
R59.9 Enlarged lymph nodes, unspecified	0.000	0.993	0.007
M67 Other disorders of synovium and tendon	0.007	0.993	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.993	0.006
E27.2 Addisonian crisis	0.000	0.993	0.006
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.994	0.006
E27.5 Adrenomedullary hyperfunction	0.000	0.994	0.006
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.994	0.006
E27.0 Other adrenocortical overactivity	0.000	0.994	0.006
D22.2 Melanocytic naevi of ear and external auricular canal	0.000	0.994	0.006
E27.8 Other specified disorders of adrenal gland	0.000	0.994	0.006
E20-E35 Disorders of other endocrine glands	0.000	0.994	0.006
D22.0 Melanocytic naevi of lip	0.000	0.994	0.006
D22.9 Melanocytic naevi, unspecified	0.000	0.994	0.005
M67.4 Ganglion	0.005	0.995	0.000
M67.1 Other contracture of tendon (sheath)	0.005	0.995	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.005	0.995	0.000
M67.3 Transient synovitis	0.005	0.995	0.000
S64.4 Injury of digital nerve of other finger	0.000	0.995	0.005
M67.2 Synovial hypertrophy, not elsewhere classified	0.005	0.995	0.000
S91.3 Open wound of other parts of foot	0.005	0.995	0.000
G82.5 Tetraplegia, unspecified	0.005	0.995	0.000
H04.2 Epiphora	0.005	0.995	0.000
E29 Testicular dysfunction	0.000	0.995	0.005
W21.9 Unspecified place	0.005	0.995	0.000
S01.1 Open wound of eyelid and periocular area	0.000	0.995	0.005
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.995	0.004
E32 Diseases of thymus	0.000	0.995	0.004
E31 Polyglandular dysfunction	0.000	0.995	0.004
E30 Disorders of puberty, not elsewhere classified	0.000	0.995	0.004
E25 Adrenogenital disorders	0.000	0.995	0.004
G82.2 Paraplegia, unspecified	0.005	0.995	0.000
M67.0 Short Achilles tendon (acquired)	0.004	0.995	0.000
E20 Hypoparathyroidism	0.000	0.995	0.004
G82 Paraplegia and tetraplegia	0.005	0.995	0.000
M67.47 Ganglion, ankle and foot	0.004	0.995	0.000
S01.2 Open wound of nose	0.000	0.996	0.004
Z48.8 Other specified surgical follow-up care	0.000	0.996	0.004
I35.0 Aortic (valve) stenosis	0.000	0.996	0.004
M67.49 Ganglion, multiple sites	0.004	0.996	0.000
M67.45 Ganglion, hip	0.004	0.996	0.000
E26 Hyperaldosteronism	0.000	0.996	0.004
S01.8 Open wound of other parts of head	0.000	0.996	0.004
E34 Other endocrine disorders	0.000	0.996	0.004
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.004	0.996	0.000
G82.1 Spastic paraplegia	0.004	0.996	0.000
E29.1 Testicular hypofunction	0.000	0.996	0.004
G82.4 Spastic tetraplegia	0.004	0.996	0.000
E24 Cushing's syndrome	0.000	0.996	0.004
E22 Hyperfunction of pituitary gland	0.000	0.996	0.004
S01 Open wound of head	0.000	0.996	0.004
M67.43 Ganglion, wrist	0.004	0.996	0.000
S91 Open wound of ankle and foot	0.004	0.996	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.996	0.004
E29.8 Other testicular dysfunction	0.000	0.996	0.004
E29.0 Testicular hyperfunction	0.000	0.996	0.004
C77.1 Intrathoracic lymph nodes	0.000	0.996	0.004
C77.0 Lymph nodes of head, face and neck	0.000	0.996	0.004
Z97.8 Presence of other specified devices	0.004	0.996	0.000
S01.0 Open wound of scalp	0.000	0.996	0.004
E25.9 Adrenogenital disorder, unspecified	0.000	0.996	0.003
E25.8 Other adrenogenital disorders	0.000	0.996	0.003
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.996	0.003
E30.9 Disorder of puberty, unspecified	0.000	0.996	0.003
E30.8 Other disorders of puberty	0.000	0.996	0.003
E30.1 Precocious puberty	0.000	0.996	0.003
E30.0 Delayed puberty	0.000	0.996	0.003
E31.9 Polyglandular dysfunction, unspecified	0.000	0.996	0.003
E31.8 Other polyglandular dysfunction	0.000	0.996	0.003
E31.1 Polyglandular hyperfunction	0.000	0.996	0.003
E31.0 Autoimmune polyglandular failure	0.000	0.996	0.003
E32.9 Disease of thymus, unspecified	0.000	0.996	0.003
E32.8 Other diseases of thymus	0.000	0.996	0.003
E32.1 Abscess of thymus	0.000	0.996	0.003
E32.0 Persistent hyperplasia of thymus	0.000	0.996	0.003
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.996	0.003
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.996	0.003
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.996	0.003
F52.2 Failure of genital response	0.004	0.996	0.000
E20.8 Other hypoparathyroidism	0.000	0.996	0.003
E20.1 Pseudohypoparathyroidism	0.000	0.996	0.003
E20.0 Idiopathic hypoparathyroidism	0.000	0.996	0.003
F20.9 Schizophrenia, unspecified	0.000	0.996	0.004
G82.3 Flaccid tetraplegia	0.003	0.996	0.000
G82.0 Flaccid paraplegia	0.003	0.996	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.996	0.004
E20.9 Hypoparathyroidism, unspecified	0.000	0.996	0.003
E28 Ovarian dysfunction	0.001	0.997	0.003
E34.8 Other specified endocrine disorders	0.000	0.997	0.003
S91.2 Open wound of toe(s) with damage to nail	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.000	0.997	0.003
E26.9 Hyperaldosteronism, unspecified	0.000	0.997	0.003
E26.8 Other hyperaldosteronism	0.000	0.997	0.003
E26.1 Secondary hyperaldosteronism	0.000	0.997	0.003
E34.5 Androgen resistance syndrome	0.000	0.997	0.003
E34.4 Constitutional tall stature	0.000	0.997	0.003
E34.3 Short stature, not elsewhere classified	0.000	0.997	0.003
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.997	0.003
E34.1 Other hypersecretion of intestinal hormones	0.000	0.997	0.003
H01.0 Blepharitis	0.000	0.997	0.003
E24.8 Other Cushing's syndrome	0.000	0.997	0.003
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.997	0.003
E24.3 Ectopic ACTH syndrome	0.000	0.997	0.003
E24.2 Drug-induced Cushing's syndrome	0.000	0.997	0.003
E24.1 Nelson's syndrome	0.000	0.997	0.003
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.997	0.003
E22.8 Other hyperfunction of pituitary gland	0.000	0.997	0.003
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.997	0.003
S91.1 Open wound of toe(s) without damage to nail	0.003	0.997	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.997	0.003
S91.7 Multiple open wounds of ankle and foot	0.003	0.997	0.000
S01.9 Open wound of head, part unspecified	0.000	0.997	0.003
E34.0 Carcinoid syndrome	0.000	0.997	0.003
S99.9 Unspecified injury of ankle and foot	0.003	0.997	0.000
V18.0 Driver injured in nontraffic accident	0.003	0.997	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.997	0.003
E28.9 Ovarian dysfunction, unspecified	0.001	0.997	0.002
E28.8 Other ovarian dysfunction	0.001	0.997	0.002
E28.1 Androgen excess	0.001	0.997	0.002
E28.0 Oestrogen excess	0.001	0.997	0.002
C77.5 Intrapelvic lymph nodes	0.000	0.997	0.003
E26.0 Primary hyperaldosteronism	0.000	0.997	0.002
F41.1 Generalised anxiety disorder	0.000	0.997	0.003
G37.9 Demyelinating disease of central nervous system, unspecified	0.003	0.997	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.003	0.997	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.997	0.002
S00.3 Superficial injury of nose	0.000	0.997	0.003
S91.0 Open wound of ankle	0.003	0.997	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.003	0.997	0.000
S01.7 Multiple open wounds of head	0.000	0.997	0.003
Z01.6 Radiological examination, not elsewhere classified	0.003	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.003	0.997	0.000
S01.4 Open wound of cheek and temporomandibular area	0.000	0.997	0.003
E28.3 Primary ovarian failure	0.001	0.997	0.002
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.997	0.002
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.997	0.002
S01.3 Open wound of ear	0.000	0.997	0.002
H65.3 Chronic mucoid otitis media	0.000	0.997	0.003
M65-M68 Disorders of synovium and tendon	0.003	0.997	0.000
T90.5 Sequelae of intracranial injury	0.002	0.997	0.000
W21 Striking against or struck by sports equipment	0.002	0.997	0.000
R00.2 Palpitations	0.000	0.998	0.002
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.002	0.998	0.000
T90 Sequelae of injuries of head	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.002	0.998	0.001
C50.5 Lower-outer quadrant of breast	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
T90.4 Sequelae of injury of eye and orbit	0.002	0.998	0.000
T90.3 Sequelae of injury of cranial nerves	0.002	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.998	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.002	0.998	0.000
S00.5 Superficial injury of lip and oral cavity	0.000	0.998	0.002
O16 Unspecified maternal hypertension	0.000	0.998	0.002
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
Z47.8 Other specified orthopaedic follow-up care	0.002	0.998	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
S92.0 Fracture of calcaneus	0.002	0.998	0.000
M66 Spontaneous rupture of synovium and tendon	0.002	0.998	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.002	0.998	0.000
K83.8 Other specified diseases of biliary tract	0.000	0.998	0.002
W21.3 Sports and athletics area	0.002	0.998	0.000
W21.8 Other specified place	0.002	0.998	0.000
W21.7 Farm	0.002	0.998	0.000
W21.6 Industrial and construction area	0.002	0.998	0.000
W21.5 Trade and service area	0.002	0.998	0.000
W21.4 Street and highway	0.002	0.998	0.000
W21.2 School, other institution and public administrative area	0.002	0.998	0.000
W21.1 Residential institution	0.002	0.998	0.000
W21.0 Home	0.002	0.998	0.000
F41 Other anxiety disorders	0.000	0.998	0.002
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.002	0.998	0.000
M23.49 Loose body in knee-Unspec lig/men	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
G25.3 Myoclonus	0.002	0.998	0.000
M66.4 Spontaneous rupture of other tendons	0.002	0.998	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.998	0.002
T90.1 Sequelae of open wound of head	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.002	0.998	0.000
S90.0 Contusion of ankle	0.002	0.998	0.000
T90.0 Sequelae of superficial injury of head	0.002	0.998	0.000
F41.2 Mixed anxiety and depressive disorder	0.000	0.998	0.002
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.002	0.998	0.000
C17.2 Ileum	0.000	0.998	0.002
S06 Intracranial injury	0.000	0.998	0.002
T91.9 Sequelae of unspecified injury of neck and trunk	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.998	0.002
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
T90.9 Sequelae of unspecified injury of head	0.002	0.998	0.000
T90.8 Sequelae of other specified injuries of head	0.002	0.998	0.000
F20 Schizophrenia	0.000	0.998	0.002
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
Z01.8 Other specified special examinations	0.002	0.998	0.000
Z60.2 Living alone	0.002	0.998	0.000
M66.3 Spontaneous rupture of flexor tendons	0.002	0.998	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.998	0.002
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
C77.8 Lymph nodes of multiple regions	0.000	0.998	0.002
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.002	0.998	0.000
S00.8 Superficial injury of other parts of head	0.000	0.998	0.002
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.000	0.998	0.002
S60.8 Other superficial injuries of wrist and hand	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
S00 Superficial injury of head	0.000	0.998	0.002
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.002	0.998	0.000
Z71.3 Dietary counselling and surveillance	0.002	0.998	0.000
N94.1 Dyspareunia	0.002	0.998	0.000
Z01.9 Special examination, unspecified	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.002	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.998	0.000
S98.1 Traumatic amputation of one toe	0.002	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.998	0.000
I22 Subsequent myocardial infarction	0.002	0.998	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.998	0.002
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.002	0.998	0.000
M66.1 Rupture of synovium	0.002	0.998	0.000
Z01.7 Laboratory examination	0.002	0.998	0.000
K74.0 Hepatic fibrosis	0.000	0.998	0.002
S06.9 Intracranial injury, unspecified	0.000	0.998	0.002
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.002	0.998	0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
Z01.2 Dental examination	0.002	0.998	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.998	0.002
W21.30 Striking against or struck by sports equipment; Sports and athletics area;While engaged in sports activity	0.001	0.998	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
C17.9 Small intestine, unspecified	0.000	0.998	0.002
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.001	0.998	0.000
M66.48 Spontaneous rupture of other tendons (Other)	0.001	0.998	0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.001	0.998	0.000
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.001	0.998	0.000
M66.44 Spontaneous rupture of other tendons (Hand)	0.001	0.998	0.000
M66.43 Spontaneous rupture of other tendons (Forearm)	0.001	0.998	0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.001	0.998	0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.001	0.998	0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.001	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.998	0.002
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.7 Excessive sexual drive	0.002	0.998	0.000
F52.6 Nonorganic dyspareunia	0.002	0.998	0.000
F52.5 Nonorganic vaginismus	0.002	0.998	0.000
F52.4 Premature ejaculation	0.002	0.998	0.000
F52.3 Orgasmic dysfunction	0.002	0.998	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.002	0.998	0.000
F52.0 Lack or loss of sexual desire	0.002	0.998	0.000
S06.8 Other intracranial injuries	0.000	0.998	0.002
F41.8 Other specified anxiety disorders	0.000	0.998	0.002
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.001	0.998	0.000
V18.5 Passenger injured in traffic accident	0.002	0.998	0.000
S00-S09 Injuries to the head	0.000	0.998	0.002
C17.0 Duodenum	0.000	0.998	0.002
M66.0 Rupture of popliteal cyst	0.002	0.998	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.998	0.002
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.001	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.998	0.001
S06.7 Intracranial injury with prolonged coma	0.000	0.998	0.002
S06.1 Traumatic cerebral oedema	0.000	0.998	0.002
S93.4 Sprain and strain of ankle	0.001	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.998	0.000
V18.3 Person injured while boarding or alighting	0.002	0.998	0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.998	0.002
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.998	0.002
F20.8 Other schizophrenia	0.000	0.998	0.002
F20.6 Simple schizophrenia	0.000	0.998	0.002
F20.5 Residual schizophrenia	0.000	0.998	0.002
F20.4 Postschizophrenic depression	0.000	0.998	0.002
F20.3 Undifferentiated schizophrenia	0.000	0.998	0.002
F20.2 Catatonic schizophrenia	0.000	0.998	0.002
F20.1 Hebephrenic schizophrenia	0.000	0.998	0.002
S06.0 Concussion	0.000	0.998	0.002
Z01.3 Examination of blood pressure	0.002	0.998	0.000
Z01.1 Examination of ears and hearing	0.002	0.998	0.000
Z01.0 Examination of eyes and vision	0.002	0.998	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.998	0.000
K83.0 Cholangitis	0.000	0.998	0.002
S92.5 Fracture of other toe	0.001	0.998	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.002	0.998	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.001	0.998	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.001	0.998	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.001	0.998	0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.001	0.998	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.001	0.998	0.000
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.001	0.998	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.001	0.998	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.001	0.998	0.000
F06.7 Mild cognitive disorder	0.002	0.998	0.000
B91 Sequelae of poliomyelitis	0.002	0.998	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.001	0.998	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.998	0.002
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.998	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.998	0.002
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.998	0.001
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.001
F20.0 Paranoid schizophrenia	0.000	0.998	0.002
F41.3 Other mixed anxiety disorders	0.000	0.998	0.001
H34.8 Other retinal vascular occlusions	0.000	0.998	0.002
K83.1 Obstruction of bile duct	0.000	0.998	0.002
K92.9 Disease of digestive system, unspecified	0.002	0.998	0.000
S92.4 Fracture of great toe	0.001	0.998	0.000
V18.1 Passenger injured in nontraffic accident	0.001	0.998	0.000
M65 Synovitis and tenosynovitis	0.002	0.998	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.998	0.002
V18.9 Unspecified pedal cyclist injured in traffic accident	0.001	0.998	0.000
V18.4 Driver injured in traffic accident	0.001	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M66.19 Rupture of synovium (Site unspecified)	0.001	0.998	0.000
M66.18 Rupture of synovium (Other)	0.001	0.998	0.000
M66.17 Rupture of synovium (Ankle and foot)	0.001	0.998	0.000
M66.16 Rupture of synovium (Lower leg)	0.001	0.998	0.000
M66.15 Rupture of synovium (Pelvic region and thigh)	0.001	0.998	0.000
M66.14 Rupture of synovium (Hand)	0.001	0.998	0.000
M66.13 Rupture of synovium (Forearm)	0.001	0.998	0.000
M66.12 Rupture of synovium (Upper arm)	0.001	0.998	0.000
M66.11 Rupture of synovium (Shoulder region)	0.001	0.998	0.000
M66.10 Rupture of synovium (Multiple sites)	0.001	0.998	0.000
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.001	0.998	0.000
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.001	0.998	0.000
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.001	0.998	0.000
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.001	0.998	0.000
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.001	0.998	0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.001	0.998	0.000
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.001	0.998	0.000
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.001	0.998	0.000
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.001	0.998	0.000
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.001	0.998	0.000
S92.11 Fracture of talus (open)	0.001	0.998	0.000
M66.2 Spontaneous rupture of extensor tendons	0.001	0.998	0.000
C17 Malignant neoplasm of small intestine	0.000	0.998	0.002
G25 Other extrapyramidal and movement disorders	0.002	0.998	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.998	0.001
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.998	0.000
C50.2 Upper-inner quadrant of breast	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.002	0.998	0.000
N94.4 Primary dysmenorrhoea	0.001	0.998	0.000
S00.7 Multiple superficial injuries of head	0.000	0.998	0.001
S00.4 Superficial injury of ear	0.000	0.998	0.001
Z01.5 Diagnostic skin and sensitisation tests	0.002	0.998	0.000
K83 Other diseases of biliary tract	0.000	0.998	0.002
E83.4 Disorders of magnesium metabolism	0.000	0.998	0.002
Q18.0 Sinus, fistula and cyst of branchial cleft	0.000	0.998	0.001
S06.3 Focal brain injury	0.000	0.998	0.001
S93.0 Dislocation of ankle joint	0.001	0.998	0.000
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.998	0.001
G25.9 Extrapyramidal and movement disorder, unspecified	0.001	0.998	0.000
M65.8 Other synovitis and tenosynovitis	0.001	0.998	0.000
N94.0 Mittelschmerz	0.001	0.998	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.998	0.002
T91.1 Sequelae of fracture of spine	0.001	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.998	0.001
G25.1 Drug-induced tremor	0.001	0.998	0.000
H01.9 Inflammation of eyelid, unspecified	0.000	0.998	0.001
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.000	0.998	0.002
N94.5 Secondary dysmenorrhoea	0.001	0.998	0.000
S06.4 Epidural haemorrhage	0.000	0.998	0.001
T91.3 Sequelae of injury of spinal cord	0.001	0.998	0.000
M66.09 Rupture of popliteal cyst-Site unspec	0.001	0.998	0.000
M66.08 Rupture of popliteal cyst-Other	0.001	0.998	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.001	0.998	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.001	0.998	0.000
M66.04 Rupture of popliteal cyst-Hand	0.001	0.998	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.001	0.998	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.001	0.998	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.001	0.998	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.001	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.998	0.001
S08 Traumatic amputation of part of head	0.000	0.998	0.001
S07 Crushing injury of head	0.000	0.998	0.001
S04 Injury of cranial nerves	0.000	0.998	0.001
S03 Dislocation, sprain and strain of joints and ligaments of head	0.000	0.998	0.001
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.001	0.999	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.999	0.001
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.999	0.001
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.999	0.001
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.999	0.001
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.999	0.001
S93.40 Sprain of unspecified ligament of ankle	0.001	0.999	0.000
E21.2 Other hyperparathyroidism	0.000	0.999	0.001
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.999	0.001
S06.01 Concussion (with open intracranial wound)	0.000	0.999	0.001
S92.10 Fracture of talus (closed)	0.001	0.999	0.000
D22.5 Melanocytic naevi of trunk	0.000	0.999	0.001
N94.2 Vaginismus	0.001	0.999	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.001	0.999	0.000
Q18.1 Preauricular sinus and cyst	0.000	0.999	0.001
S93.1 Dislocation of toe(s)	0.001	0.999	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.001	0.999	0.000
H01 Other inflammation of eyelid	0.000	0.999	0.001
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.001	0.999	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.999	0.001
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.999	0.001
I22.9 Subsequent myocardial infarction of unspecified site	0.001	0.999	0.000
K83.9 Disease of biliary tract, unspecified	0.000	0.999	0.001
M65.2 Calcific tendinitis	0.001	0.999	0.000
M65.0 Abscess of tendon sheath	0.001	0.999	0.000
Y44.2 Anticoagulants	0.000	0.999	0.001
G37 Other demyelinating diseases of central nervous system	0.001	0.999	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.001	0.999	0.000
S06.00 Concussion (without open intracranial wound)	0.000	0.999	0.001
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.001	0.999	0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.001	0.999	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.000	0.999	0.001
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.001	0.999	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.001	0.999	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.001	0.999	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.001	0.999	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.001	0.999	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.001	0.999	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.001	0.999	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.001	0.999	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.001	0.999	0.000
C17.8 Overlapping lesion of small intestine	0.000	0.999	0.001
C17.3 Meckel's diverticulum	0.000	0.999	0.001
C17.1 Jejunum	0.000	0.999	0.001
G25.6 Drug-induced tics and other tics of organic origin	0.001	0.999	0.000
G25.5 Other chorea	0.001	0.999	0.000
G25.4 Drug-induced chorea	0.001	0.999	0.000
I22.8 Subsequent myocardial infarction of other sites	0.001	0.999	0.000
K83.5 Biliary cyst	0.000	0.999	0.001
K83.4 Spasm of sphincter of Oddi	0.000	0.999	0.001
K83.2 Perforation of bile duct	0.000	0.999	0.001
M41.9 Scoliosis, unspecified	0.001	0.999	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.001	0.999	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.001	0.999	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.001	0.999	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations