TreeWAS – Variant ID: rs17202259

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C44.3 Skin of other and unspecified parts of face	1.000	0.000	0.000
E10.9 Without complications	0.000	0.000	1.000
K51.9 Ulcerative colitis, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
C44 Other malignant neoplasms of skin	1.000	0.000	0.000
K51 Ulcerative colitis	1.000	0.000	0.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
C44.7 Skin of lower limb, including hip	0.999	0.001	0.000
K50-K52 Noninfective enteritis and colitis	0.999	0.001	0.000
K50 Crohn's disease [regional enteritis]	0.999	0.001	0.000
K50.1 Crohn's disease of large intestine	0.999	0.001	0.000
Z93.2 Ileostomy status	0.997	0.003	0.000
K51.4 Pseudopolyposis of colon	0.993	0.007	0.000
C44.4 Skin of scalp and neck	0.991	0.009	0.000
E10.1 With ketoacidosis	0.000	0.012	0.988
E10.3 With ophthalmic complications	0.000	0.013	0.987
C44.2 Skin of ear and external auricular canal	0.986	0.014	0.000
C44.6 Skin of upper limb, including shoulder	0.983	0.017	0.000
C44.5 Skin of trunk	0.979	0.021	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.968	0.032	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.957	0.043	0.000
K51.8 Other ulcerative colitis	0.957	0.043	0.000
K51.2 Ulcerative (chronic) proctitis	0.945	0.055	0.000
C44.0 Skin of lip	0.940	0.060	0.000
K50.9 Crohn's disease, unspecified	0.932	0.068	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.069	0.931
D86 Sarcoidosis	0.000	0.075	0.925
D86.0 Sarcoidosis of lung	0.000	0.085	0.915
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.912	0.088	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.901	0.099	0.000
C83.3 Large cell (diffuse)	0.900	0.100	0.000
C82.0 Small cleaved cell, follicular	0.871	0.129	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.869	0.131	0.000
K52 Other non-infective gastro-enteritis and colitis	0.860	0.140	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.841	0.159	0.000
E10.8 With unspecified complications	0.000	0.165	0.835
K51.5 Mucosal proctocolitis	0.829	0.171	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.179	0.821
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.180	0.820
D50-D53 Nutritional anaemias	0.000	0.184	0.816
D80-D89 Certain disorders involving the immune mechanism	0.000	0.197	0.803
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.791	0.209	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.217	0.783
C44.9 Malignant neoplasm of skin, unspecified	0.783	0.217	0.000
D50 Iron deficiency anaemia	0.000	0.218	0.782
D50.9 Iron deficiency anaemia, unspecified	0.000	0.222	0.778
K52.1 Toxic gastro-enteritis and colitis	0.778	0.222	0.000
C82.3 Follicular lymphoma grade IIIa	0.775	0.225	0.000
E10-E14 Diabetes mellitus	0.000	0.232	0.768
E10.0 With coma	0.000	0.233	0.767
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.235	0.765
C44.1 Skin of eyelid, including canthus	0.757	0.243	0.000
K90 Intestinal malabsorption	0.000	0.250	0.750
K52.8 Other specified non-infective gastro-enteritis and colitis	0.749	0.251	0.000
E10.4 With neurological complications	0.000	0.252	0.748
E10.6 With other specified complications	0.000	0.253	0.747
K51.3 Ulcerative (chronic) rectosigmoiditis	0.721	0.279	0.000
K50.8 Other Crohn's disease	0.720	0.280	0.000
C44.8 Overlapping lesion of skin	0.717	0.283	0.000
E10.7 With multiple complications	0.000	0.283	0.717
K51.0 Ulcerative (chronic) enterocolitis	0.712	0.288	0.000
K52.3 Indeterminate colitis	0.707	0.293	0.000
C83.1 Small cleaved cell (diffuse)	0.698	0.302	0.000
E10.2 With renal complications	0.000	0.303	0.697
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.311	0.689
E16 Other disorders of pancreatic internal secretion	0.000	0.312	0.688
E16.2 Hypoglycaemia, unspecified	0.000	0.312	0.688
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.313	0.687
C82.6 Cutaneous follicle centre lymphoma	0.686	0.314	0.000
C82.5 Diffuse follicle centre lymphoma	0.686	0.314	0.000
C82.4 Follicular lymphoma grade IIIb	0.686	0.314	0.000
C81 Hodgkin's disease	0.684	0.316	0.000
C85.1 B-cell lymphoma, unspecified	0.669	0.331	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.336	0.664
D86.8 Sarcoidosis of other and combined sites	0.000	0.337	0.663
D86.3 Sarcoidosis of skin	0.000	0.337	0.663
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.337	0.663
D86.1 Sarcoidosis of lymph nodes	0.000	0.337	0.663
C82.1 Mixed small cleaved and large cell, follicular	0.656	0.344	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.654	0.346	0.000
C94 Other leukaemias of specified cell type	0.654	0.346	0.000
C93 Monocytic leukaemia	0.654	0.346	0.000
C86 Other specified types of T/NK-cell lymphoma	0.654	0.346	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.348	0.652
C82.2 Large cell, follicular	0.648	0.351	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.647	0.353	0.000
C83.6 Undifferentiated (diffuse)	0.646	0.354	0.000
C83.5 Lymphoblastic (diffuse)	0.646	0.354	0.000
C83.4 Immunoblastic (diffuse)	0.646	0.354	0.000
C83.2 Mixed small and large cell (diffuse)	0.646	0.354	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.645	0.355	0.000
E27 Other disorders of adrenal gland	0.000	0.357	0.643
C43-C44 Melanoma and other malignant neoplasms of skin	0.642	0.358	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.360	0.640
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.633	0.367	0.000
C83.7 Burkitt's tumour	0.626	0.374	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.623	0.377	0.000
C85.0 Lymphosarcoma	0.623	0.377	0.000
E10.5 With peripheral circulatory complications	0.000	0.378	0.622
D52 Folate deficiency anaemia	0.000	0.386	0.614
C95 Leukaemia of unspecified cell type	0.602	0.398	0.000
E13 Other specified diabetes mellitus	0.000	0.399	0.601
K90.9 Intestinal malabsorption, unspecified	0.000	0.402	0.598
C84 Peripheral and cutaneous T-cell lymphomas	0.592	0.408	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.411	0.589
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.411	0.589
D51.2 Transcobalamin II deficiency	0.000	0.411	0.589
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.411	0.589
E22 Hyperfunction of pituitary gland	0.000	0.412	0.588
C88 Malignant immunoproliferative diseases	0.578	0.422	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.424	0.575
D81 Combined immunodeficiencies	0.000	0.424	0.575
K90.8 Other intestinal malabsorption	0.000	0.436	0.564
D50.1 Sideropenic dysphagia	0.000	0.439	0.561
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.561	0.439	0.000
D53 Other nutritional anaemias	0.000	0.439	0.560
D55-D59 Haemolytic anaemias	0.000	0.446	0.554
E16.1 Other hypoglycaemia	0.000	0.449	0.551
E12 Malnutrition-related diabetes mellitus	0.000	0.449	0.550
C81.1 Nodular sclerosis	0.549	0.451	0.000
E14 Unspecified diabetes mellitus	0.000	0.455	0.545
C85.7 Other specified types of non-Hodgkin's lymphoma	0.540	0.460	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.462	0.538
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.462	0.538
K90.1 Tropical sprue	0.000	0.462	0.538
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.465	0.535
D83 Common variable immunodeficiency	0.000	0.474	0.526
C81.2 Mixed cellularity	0.523	0.477	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.479	0.521
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.481	0.519
C81.0 Lymphocytic predominance	0.519	0.481	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.484	0.516
C90 Multiple myeloma and malignant plasma cell neoplasms	0.502	0.498	0.000
E24 Cushing's syndrome	0.000	0.500	0.500
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.506	0.494
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.506	0.494
E16.4 Abnormal secretion of gastrin	0.000	0.506	0.494
E16.3 Increased secretion of glucagon	0.000	0.506	0.494
E15 Nondiabetic hypoglycaemic coma	0.000	0.507	0.493
C81.7 Other Hodgkin's disease	0.490	0.510	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.490	0.510	0.000
C81.3 Lymphocytic depletion	0.490	0.510	0.000
E13.9 Without complications	0.000	0.518	0.482
D80 Immunodeficiency with predominantly antibody defects	0.000	0.518	0.482
E27.2 Addisonian crisis	0.000	0.521	0.479
D59 Acquired haemolytic anaemia	0.000	0.525	0.475
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.469	0.531	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.469	0.531	0.000
C86.4 Blastic NK-cell lymphoma	0.469	0.531	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.469	0.531	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.469	0.531	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.469	0.531	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.469	0.531	0.000
C93.9 Monocytic leukaemia, unspecified	0.469	0.531	0.000
C93.7 Other monocytic leukaemia	0.469	0.531	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.469	0.531	0.000
C93.2 Subacute monocytic leukaemia	0.469	0.531	0.000
C93.1 Chronic monocytic leukaemia	0.469	0.531	0.000
C93.0 Acute monocytic leukaemia	0.469	0.531	0.000
C94.7 Other specified leukaemias	0.469	0.531	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.469	0.531	0.000
C94.5 Acute myelofibrosis	0.469	0.531	0.000
C94.4 Acute panmyelosis	0.469	0.531	0.000
C94.3 Mast cell leukaemia	0.469	0.531	0.000
C94.2 Acute megakaryoblastic leukaemia	0.469	0.531	0.000
C94.1 Chronic erythraemia	0.469	0.531	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.469	0.531	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.469	0.531	0.000
C96.8 Histiocytic sarcoma	0.469	0.531	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.469	0.531	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.469	0.531	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.469	0.531	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.469	0.531	0.000
C96.3 True histiocytic lymphoma	0.469	0.531	0.000
C96.2 Malignant mast cell tumour	0.469	0.531	0.000
C96.1 Malignant histiocytosis	0.469	0.531	0.000
C96.0 Letterer-Siwe disease	0.469	0.531	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.531	0.468
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.533	0.467
E32 Diseases of thymus	0.000	0.533	0.467
E31 Polyglandular dysfunction	0.000	0.533	0.467
E30 Disorders of puberty, not elsewhere classified	0.000	0.533	0.467
E25 Adrenogenital disorders	0.000	0.533	0.467
E20 Hypoparathyroidism	0.000	0.534	0.466
D84 Other immunodeficiencies	0.001	0.537	0.463
E27.5 Adrenomedullary hyperfunction	0.000	0.539	0.461
E27.0 Other adrenocortical overactivity	0.000	0.539	0.461
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.541	0.459
K52.0 Gastro-enteritis and colitis due to radiation	0.459	0.541	0.000
E34 Other endocrine disorders	0.000	0.543	0.457
E40-E46 Malnutrition	0.000	0.544	0.456
Chapter II Neoplasms	0.455	0.545	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.453	0.547	0.000
C73 Malignant neoplasm of thyroid gland	0.453	0.547	0.000
C91 Lymphoid leukaemia	0.448	0.551	0.001
E14.9 Without complications	0.000	0.552	0.448
E22.0 Acromegaly and pituitary gigantism	0.000	0.557	0.443
D52.8 Other folate deficiency anaemias	0.000	0.560	0.440
D52.1 Drug-induced folate deficiency anaemia	0.000	0.560	0.440
D52.0 Dietary folate deficiency anaemia	0.000	0.560	0.440
E27.8 Other specified disorders of adrenal gland	0.000	0.564	0.436
E21.0 Primary hyperparathyroidism	0.000	0.567	0.433
C95.7 Other leukaemia of unspecified cell type	0.431	0.568	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.431	0.568	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.431	0.568	0.000
C95.0 Acute leukaemia of unspecified cell type	0.431	0.568	0.000
E13.8 With unspecified complications	0.000	0.569	0.431
E13.7 With multiple complications	0.000	0.569	0.431
E13.6 With other specified complications	0.000	0.569	0.431
E13.5 With peripheral circulatory complications	0.000	0.569	0.431
E13.4 With neurological complications	0.000	0.569	0.431
E13.3 With ophthalmic complications	0.000	0.569	0.431
E13.2 With renal complications	0.000	0.569	0.431
E13.1 With ketoacidosis	0.000	0.569	0.431
E13.0 With coma	0.000	0.569	0.431
E22.1 Hyperprolactinaemia	0.000	0.574	0.426
C84.9 Mature T/NK-cell lymphoma, unspecified	0.425	0.575	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.425	0.575	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.425	0.575	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.425	0.575	0.000
C84.3 Lymphoepithelioid lymphoma	0.425	0.575	0.000
C84.2 T-zone lymphoma	0.425	0.575	0.000
C84.1 Sezary's diease	0.425	0.575	0.000
C84.0 Mycosis fungoides	0.422	0.577	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.578	0.422
E22.8 Other hyperfunction of pituitary gland	0.000	0.578	0.422
M06.9 Rheumatoid arthritis, unspecified	0.418	0.582	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.584	0.415
C88.9 Malignant immunoproliferative disease, unspecified	0.415	0.585	0.000
C88.7 Other malignant immunoproliferative diseases	0.415	0.585	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.415	0.585	0.000
C88.3 Immunoproliferative small intestinal disease	0.415	0.585	0.000
C88.2 Gamma heavy chain disease	0.415	0.585	0.000
C88.1 Alpha heavy chain disease	0.415	0.585	0.000
M06.0 Seronegative rheumatoid arthritis	0.414	0.586	0.000
M06 Other rheumatoid arthritis	0.414	0.586	0.000
D81.9 Combined immunodeficiency, unspecified	0.000	0.587	0.413
D81.8 Other combined immunodeficiencies	0.000	0.587	0.413
D81.7 Major histocompatibility complex class II deficiency	0.000	0.587	0.413
D81.6 Major histocompatibility complex class I deficiency	0.000	0.587	0.413
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.587	0.413
D81.4 Nezelof's syndrome	0.000	0.587	0.413
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.587	0.413
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.587	0.413
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.587	0.413
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.587	0.413
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.587	0.413
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.587	0.413
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.587	0.413
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.587	0.413
D82.2 Immunodeficiency with short-limbed stature	0.000	0.587	0.413
D82.1 Di George's syndrome	0.000	0.587	0.413
D82.0 Wiskott-Aldrich syndrome	0.000	0.587	0.413
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.588	0.412
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.410	0.590	0.000
D53.8 Other specified nutritional anaemias	0.000	0.598	0.402
D53.2 Scorbutic anaemia	0.000	0.598	0.402
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.598	0.402
D53.0 Protein deficiency anaemia	0.000	0.598	0.402
E00-E07 Disorders of thyroid gland	0.000	0.599	0.401
C84.4 Peripheral T-cell lymphoma	0.399	0.600	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.399	0.601	0.000
E29 Testicular dysfunction	0.000	0.601	0.399
E14.3 With ophthalmic complications	0.000	0.601	0.399
D57 Sickle-cell disorders	0.000	0.603	0.397
D55 Anaemia due to enzyme disorders	0.000	0.603	0.397
C84.5 Other and unspecified T-cell lymphomas	0.396	0.604	0.000
E12.9 Without complications	0.000	0.605	0.395
E12.8 With unspecified complications	0.000	0.605	0.395
E12.7 With multiple complications	0.000	0.605	0.395
E12.6 With other specified complications	0.000	0.605	0.395
E12.5 With peripheral circulatory complications	0.000	0.605	0.395
E12.4 With neurological complications	0.000	0.605	0.395
E12.3 With ophthalmic complications	0.000	0.605	0.395
E12.2 With renal complications	0.000	0.605	0.395
E12.1 With ketoacidosis	0.000	0.605	0.395
E12.0 With coma	0.000	0.605	0.395
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.393	0.607	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.608	0.392
E24.9 Cushing's syndrome, unspecified	0.000	0.608	0.392
C43 Malignant melanoma of skin	0.392	0.608	0.000
E14.8 With unspecified complications	0.000	0.609	0.391
E14.7 With multiple complications	0.000	0.609	0.391
E14.2 Withrenal complications	0.000	0.609	0.391
E14.1 With ketoacidosis	0.000	0.609	0.391
E14.0 With coma	0.000	0.609	0.391
C91.5 Adult T-cell leukaemia	0.385	0.615	0.001
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.617	0.383
C95.9 Leukaemia, unspecified	0.380	0.620	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.620	0.380
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.379	0.621	0.000
E34.0 Carcinoid syndrome	0.000	0.622	0.378
D53.9 Nutritional anaemia, unspecified	0.000	0.622	0.377
D83.8 Other common variable immunodeficiencies	0.000	0.622	0.377
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.622	0.377
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.622	0.377
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.622	0.377
E14.6 With other specified complications	0.000	0.624	0.376
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.373	0.627	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.630	0.370
E21.4 Other specified disorders of parathyroid gland	0.000	0.630	0.370
E21.2 Other hyperparathyroidism	0.000	0.630	0.370
E03 Other hypothyroidism	0.000	0.632	0.368
J45 Asthma	0.000	0.634	0.366
C83.0 Small cell (diffuse)	0.365	0.635	0.001
C92 Myeloid leukaemia	0.362	0.638	0.000
C91.9 Lymphoid leukaemia, unspecified	0.362	0.638	0.001
C90.3 Solitary plasmacytoma	0.360	0.640	0.000
C90.1 Plasma cell leukaemia	0.360	0.640	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.360	0.640	0.000
E24.8 Other Cushing's syndrome	0.000	0.641	0.359
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.641	0.359
E24.3 Ectopic ACTH syndrome	0.000	0.641	0.359
E24.2 Drug-induced Cushing's syndrome	0.000	0.641	0.359
E24.1 Nelson's syndrome	0.000	0.641	0.359
E24.0 Pituitary-dependent Cushing's disease	0.000	0.641	0.359
E14.5 With peripheral circulatory complications	0.000	0.644	0.356
C02 Malignant neoplasm of other and unspecified parts of tongue	0.352	0.648	0.000
C81.9 Hodgkin's disease, unspecified	0.351	0.648	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.350	0.650	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.651	0.349
C43.6 Malignant melanoma of upper limb, including shoulder	0.348	0.652	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.653	0.347
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.654	0.345
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.654	0.345
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.654	0.345
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.654	0.345
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.654	0.345
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.654	0.345
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.654	0.345
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.654	0.345
E14.4 With neurological complications	0.000	0.655	0.345
D59.8 Other acquired haemolytic anaemias	0.000	0.659	0.341
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.659	0.341
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.659	0.341
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.659	0.341
D59.3 Haemolytic-uraemic syndrome	0.000	0.659	0.341
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.659	0.341
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.659	0.341
C74 Malignant neoplasm of adrenal gland	0.340	0.660	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.339	0.660	0.000
C43.4 Malignant melanoma of scalp and neck	0.338	0.662	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.337	0.663	0.000
D56 Thalassaemia	0.000	0.664	0.336
E25.9 Adrenogenital disorder, unspecified	0.000	0.665	0.335
E25.8 Other adrenogenital disorders	0.000	0.665	0.335
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.665	0.335
E30.9 Disorder of puberty, unspecified	0.000	0.665	0.335
E30.8 Other disorders of puberty	0.000	0.665	0.335
E30.1 Precocious puberty	0.000	0.665	0.335
E30.0 Delayed puberty	0.000	0.665	0.335
E31.9 Polyglandular dysfunction, unspecified	0.000	0.665	0.335
E31.8 Other polyglandular dysfunction	0.000	0.665	0.335
E31.1 Polyglandular hyperfunction	0.000	0.665	0.335
E31.0 Autoimmune polyglandular failure	0.000	0.665	0.335
E32.9 Disease of thymus, unspecified	0.000	0.665	0.335
E32.8 Other diseases of thymus	0.000	0.665	0.335
E32.1 Abscess of thymus	0.000	0.665	0.335
E32.0 Persistent hyperplasia of thymus	0.000	0.665	0.335
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.665	0.335
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.665	0.335
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.665	0.335
E20.8 Other hypoparathyroidism	0.000	0.665	0.334
E20.1 Pseudohypoparathyroidism	0.000	0.665	0.334
E20.0 Idiopathic hypoparathyroidism	0.000	0.665	0.334
E20.9 Hypoparathyroidism, unspecified	0.000	0.666	0.333
D84.8 Other specified immunodeficiencies	0.001	0.668	0.332
D84.1 Defects in the complement system	0.001	0.668	0.332
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.668	0.332
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.669	0.331
D83.9 Common variable immunodeficiency, unspecified	0.000	0.672	0.328
E34.5 Androgen resistance syndrome	0.000	0.672	0.328
E34.4 Constitutional tall stature	0.000	0.672	0.328
E34.3 Short stature, not elsewhere classified	0.000	0.672	0.328
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.672	0.328
E34.1 Other hypersecretion of intestinal hormones	0.000	0.672	0.328
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.673	0.327
E45 Retarded development following protein-energy malnutrition	0.000	0.673	0.327
E43 Unspecified severe protein-energy malnutrition	0.000	0.673	0.327
E42 Marasmic kwashiorkor	0.000	0.673	0.327
E41 Nutritional marasmus	0.000	0.673	0.327
E40 Kwashiorkor	0.000	0.673	0.327
C75 Malignant neoplasm of other endocrine glands and related structures	0.325	0.675	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.324	0.676	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.321	0.678	0.001
C91.7 Other lymphoid leukaemia	0.321	0.678	0.001
C91.6 Prolymphocytic leukaemia of T-cell type	0.321	0.678	0.001
C91.3 Prolymphocytic leukaemia	0.321	0.678	0.001
C91.2 Subacute lymphocytic leukaemia	0.321	0.678	0.001
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.320	0.680	0.000
C02.1 Border of tongue	0.319	0.680	0.000
D58 Other hereditary haemolytic anaemias	0.000	0.682	0.317
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.315	0.685	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.686	0.314
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.314	0.686	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.687	0.313
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.312	0.688	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.688	0.312
C06 Malignant neoplasm of other and unspecified parts of mouth	0.312	0.688	0.000
C05 Malignant neoplasm of palate	0.308	0.692	0.000
C90.0 Multiple myeloma	0.307	0.693	0.000
E50-E64 Other nutritional deficiencies	0.000	0.696	0.304
M05-M14 Inflammatory polyarthropathies	0.302	0.698	0.000
E34.8 Other specified endocrine disorders	0.000	0.698	0.302
E28 Ovarian dysfunction	0.000	0.698	0.301
M06.08 Seronegative rheumatoid arthritis (Other)	0.297	0.703	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.297	0.703	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.297	0.703	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.297	0.703	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.297	0.703	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.297	0.703	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.297	0.703	0.000
M06.8 Other specified rheumatoid arthritis	0.297	0.703	0.000
M06.2 Rheumatoid bursitis	0.297	0.703	0.000
M06.1 Adult-onset Still's disease	0.297	0.703	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.703	0.297
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.704	0.296
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.704	0.296
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.704	0.296
D89.3 Immune reconstitution syndrome	0.000	0.704	0.296
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.704	0.296
E27.9 Disorder of adrenal gland, unspecified	0.001	0.705	0.295
M06.3 Rheumatoid nodule	0.292	0.708	0.000
C03 Malignant neoplasm of gum	0.291	0.709	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.711	0.289
C90.2 Plasmacytoma, extramedullary	0.288	0.712	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.712	0.288
E00 Congenital iodine-deficiency syndrome	0.000	0.712	0.288
E29.9 Testicular dysfunction, unspecified	0.000	0.714	0.286
E29.8 Other testicular dysfunction	0.000	0.714	0.286
E29.0 Testicular hyperfunction	0.000	0.714	0.286
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.715	0.285
D55.8 Other anaemias due to enzyme disorders	0.000	0.715	0.285
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.715	0.285
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.715	0.285
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.715	0.285
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.715	0.285
D57.8 Other sickle-cell disorders	0.000	0.715	0.285
D57.3 Sickle-cell trait	0.000	0.715	0.285
D57.2 Double heterozygous sickling disorders	0.000	0.715	0.285
D57.1 Sickle-cell anaemia without crisis	0.000	0.715	0.285
D57.0 Sickle-cell anaemia with crisis	0.000	0.715	0.285
C10 Malignant neoplasm of oropharynx	0.284	0.716	0.000
M06.4 Inflammatory polyarthropathy	0.282	0.718	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.281	0.718	0.000
C43.8 Overlapping malignant melanoma of skin	0.281	0.719	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.281	0.719	0.000
C43.0 Malignant melanoma of lip	0.281	0.719	0.000
E26 Hyperaldosteronism	0.001	0.721	0.278
M07 Psoriatic and enteropathic arthropathies	0.277	0.723	0.000
C02.2 Ventral surface of tongue	0.276	0.724	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.275	0.725	0.000
C02.9 Tongue, unspecified	0.274	0.725	0.000
E67 Other hyperalimentation	0.000	0.727	0.272
E68 Sequelae of hyperalimentation	0.000	0.727	0.272
C13 Malignant neoplasm of hypopharynx	0.272	0.728	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.272	0.728	0.000
C00 Malignant neoplasm of lip	0.272	0.728	0.000
M05 Seropositive rheumatoid arthritis	0.271	0.729	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.732	0.268
E34.9 Endocrine disorder, unspecified	0.000	0.733	0.266
C12 Malignant neoplasm of pyriform sinus	0.266	0.734	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.265	0.735	0.000
C91.0 Acute lymphoblastic leukaemia	0.264	0.735	0.001
E03.5 Myxoedema coma	0.000	0.736	0.264
E03.4 Atrophy of thyroid (acquired)	0.000	0.736	0.264
E03.3 Postinfectious hypothyroidism	0.000	0.736	0.264
E03.1 Congenital hypothyroidism without goitre	0.000	0.736	0.264
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.736	0.264
J45.8 Mixed asthma	0.000	0.737	0.263
J45.1 Nonallergic asthma	0.000	0.737	0.263
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.262	0.738	0.000
C11 Malignant neoplasm of nasopharynx	0.261	0.739	0.000
C92.9 Myeloid leukaemia, unspecified	0.260	0.740	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.260	0.740	0.000
C92.7 Other myeloid leukaemia	0.260	0.740	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.260	0.740	0.000
C92.5 Acute myelomonocytic leukaemia	0.260	0.740	0.000
C92.4 Acute promyelocytic leukaemia	0.260	0.740	0.000
C92.3 Myeloid sarcoma	0.260	0.740	0.000
C92.2 Subacute myeloid leukaemia	0.260	0.740	0.000
M07.3 Other psoriatic arthropathies	0.259	0.741	0.000
C74.9 Adrenal gland, unspecified	0.259	0.741	0.000
D89.1 Cryoglobulinaemia	0.000	0.743	0.256
E06 Thyroiditis	0.000	0.746	0.254
C43.3 Malignant melanoma of other and unspecified parts of face	0.254	0.746	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.746	0.254
C06.0 Cheek mucosa	0.253	0.747	0.000
C02.8 Overlapping lesion of tongue	0.252	0.747	0.000
C02.4 Lingual tonsil	0.252	0.747	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.252	0.747	0.000
C02.0 Dorsal surface of tongue	0.252	0.747	0.000
D50.8 Other iron deficiency anaemias	0.000	0.749	0.251
M05.9 Seropositive rheumatoid arthritis, unspecified	0.249	0.751	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.249	0.751	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.753	0.247
C05.1 Soft palate	0.245	0.755	0.000
C74.1 Medulla of adrenal gland	0.244	0.756	0.000
C74.0 Cortex of adrenal gland	0.244	0.756	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations