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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17221417
log Bayes Factor = 8.74535
Chromosome 16   position 50,739,582  (GRCh37) Explore rs17221417 on Ensembl!
Variant rs17221417 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K50.9 Crohn's disease, unspecified
1.000 0.000 0.000
K50 Crohn's disease [regional enteritis]
1.000 0.000 0.000
K50.1 Crohn's disease of large intestine
0.999 0.001 0.000
K50.0 Crohn's disease of small intestine
0.999 0.001 0.000
K50.8 Other Crohn's disease
0.982 0.018 0.000
F40.2 Specific (isolated) phobias
0.000 0.623 0.377
F40 Phobic anxiety disorders
0.000 0.744 0.256
F40.9 Phobic anxiety disorder, unspecified
0.000 0.795 0.204
F40.8 Other phobic anxiety disorders
0.000 0.816 0.183
F40.1 Social phobias
0.000 0.816 0.183
F40.0 Agoraphobia
0.000 0.823 0.177
F40-F48 Neurotic, stress-related and somatoform disorders
0.000 0.856 0.144
F41 Other anxiety disorders
0.000 0.861 0.139
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.000 0.863 0.137
F41.2 Mixed anxiety and depressive disorder
0.000 0.870 0.130
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.875 0.125
J84 Other interstitial pulmonary diseases
0.000 0.879 0.121
J84.8 Other specified interstitial pulmonary diseases
0.000 0.883 0.117
F41.8 Other specified anxiety disorders
0.000 0.887 0.113
F48 Other neurotic disorders
0.000 0.892 0.108
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.894 0.106
F43 Reaction to severe stress, and adjustment disorders
0.000 0.899 0.101
F43.0 Acute stress reaction
0.000 0.909 0.091
J84.0 Alveolar and parietoalveolar conditions
0.000 0.913 0.087
F48.9 Neurotic disorder, unspecified
0.000 0.916 0.084
F42 Obsessive-compulsive disorder
0.000 0.916 0.083
K50-K52 Noninfective enteritis and colitis
0.082 0.918 0.000
F41.3 Other mixed anxiety disorders
0.000 0.918 0.082
F43.1 Posttraumatic stress disorder
0.000 0.919 0.081
F44 Dissociative [conversion] disorders
0.000 0.921 0.079
F48.8 Other specified neurotic disorders
0.000 0.922 0.078
F48.1 Depersonalisation-derealisation syndrome
0.000 0.922 0.078
F48.0 Neurasthenia
0.000 0.925 0.075
F45 Somatoform disorders
0.000 0.925 0.075
F43.8 Other reactions to severe stress
0.000 0.927 0.073
F42.0 Predominantly obsessional thoughts or ruminations
0.000 0.933 0.067
Y52 Agents primarily affecting the cardiovascular system
0.000 0.933 0.067
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.936 0.064
Y52.1 Calcium-channel blockers
0.000 0.936 0.064
F41.1 Generalised anxiety disorder
0.000 0.937 0.063
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.938 0.062
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.939 0.061
F42.8 Other obsessive-compulsive disorders
0.000 0.940 0.060
F42.2 Mixed obsessional thoughts and acts
0.000 0.940 0.060
F42.1 Predominantly compulsive acts [obsessional rituals]
0.000 0.940 0.060
Y52.3 Coronary vasodilators, not elsewhere classified
0.000 0.940 0.060
Y52.4 Angiotensin-converting-enzyme inhibitors
0.000 0.941 0.059
F45.9 Somatoform disorder, unspecified
0.000 0.943 0.057
F44.8 Other dissociative [conversion] disorders
0.000 0.943 0.057
F44.7 Mixed dissociative [conversion] disorders
0.000 0.943 0.057
F44.6 Dissociative anaesthesia and sensory loss
0.000 0.943 0.057
F44.3 Trance and possession disorders
0.000 0.943 0.057
F44.2 Dissociative stupor
0.000 0.943 0.057
F44.1 Dissociative fugue
0.000 0.943 0.057
F44.0 Dissociative amnesia
0.000 0.943 0.057
J80 Adult respiratory distress syndrome
0.000 0.944 0.056
F44.5 Dissociative convulsions
0.000 0.944 0.056
F45.4 Persistent somatoform pain disorder
0.000 0.945 0.055
F44.9 Dissociative [conversion] disorder, unspecified
0.000 0.945 0.054
F45.1 Undifferentiated somatoform disorder
0.000 0.946 0.054
F45.0 Somatisation disorder
0.000 0.947 0.053
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.950 0.050
F41.9 Anxiety disorder, unspecified
0.000 0.950 0.050
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.950 0.049
Y52.7 Peripheral vasodilators
0.000 0.951 0.049
Y52.8 Antivaricose drugs, including sclerosing agents
0.000 0.952 0.048
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.952 0.048
F43.9 Reaction to severe stress, unspecified
0.000 0.952 0.047
F45.2 Hypochondriacal disorder
0.000 0.954 0.045
F45.8 Other somatoform disorders
0.000 0.955 0.045
F45.3 Somatoform autonomic dysfunction
0.000 0.956 0.044
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.957 0.043
F44.4 Dissociative motor disorders
0.001 0.961 0.039
F43.2 Adjustment disorders
0.000 0.966 0.034
K51 Ulcerative colitis
0.023 0.977 0.000
J81 Pulmonary oedema
0.000 0.978 0.022
F42.9 Obsessive-compulsive disorder, unspecified
0.001 0.978 0.021
K51.5 Mucosal proctocolitis
0.021 0.979 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.020 0.980 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.018 0.982 0.000
K51.8 Other ulcerative colitis
0.016 0.984 0.000
Z39.0 Care and examination immediately after delivery
0.000 0.985 0.015
Z39 Postpartum care and examination
0.000 0.987 0.013
Z39.2 Routine postpartum follow-up
0.000 0.987 0.013
Z39.1 Care and examination of lactating mother
0.000 0.989 0.011
Y40.9 Systemic antibiotic, unspecified
0.000 0.989 0.011
K51.3 Ulcerative (chronic) rectosigmoiditis
0.011 0.989 0.000
K51.4 Pseudopolyposis of colon
0.011 0.989 0.000
K52 Other non-infective gastro-enteritis and colitis
0.009 0.991 0.000
H50.5 Heterophoria
0.007 0.993 0.000
Z43.5 Attention to cyctostomy
0.000 0.993 0.007
H50.0 Convergent concomitant strabismus
0.007 0.993 0.000
K52.3 Indeterminate colitis
0.007 0.993 0.000
Z43 Attention to artificial openings
0.000 0.993 0.007
Z43.4 Attention to other artificial openings of digestive tract
0.000 0.993 0.007
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.006 0.993 0.000
Z43.3 Attention to colostomy
0.000 0.993 0.007
H50 Other strabismus
0.006 0.994 0.000
Y40 Systemic antibiotics
0.000 0.994 0.006
Z43.0 Attention to tracheostomy
0.000 0.994 0.006
H50.2 Vertical strabismus
0.006 0.994 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.000 0.994 0.006
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.000 0.994 0.006
Y54.3 Benzothiadiazine derivatives
0.000 0.994 0.005
Z43.6 Attention to other artificial openings of urinary tract
0.000 0.994 0.006
Z43.1 Attention to gastrostomy
0.000 0.995 0.005
K52.0 Gastro-enteritis and colitis due to radiation
0.005 0.995 0.000
H50.8 Other specified strabismus
0.005 0.995 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.000 0.995 0.005
Z43.9 Attention to unspecified artificial opening
0.000 0.995 0.005
Z43.7 Attention to artificial vagina
0.000 0.995 0.005
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.000 0.995 0.005
Y41.0 Sulphonamides
0.000 0.995 0.005
Y41.5 Antiviral drugs
0.000 0.995 0.005
Z43.8 Attention to other artificial openings
0.000 0.995 0.005
H50.6 Mechanical strabismus
0.005 0.995 0.000
H50.3 Intermittent heterotropia
0.005 0.995 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.995 0.005
H50.4 Other and unspecified heterotropia
0.005 0.995 0.000
Y58 Bacterial vaccines
0.000 0.995 0.005
T78.4 Allergy, unspecified
0.005 0.995 0.000
Y41.1 Antimycobacterial drugs
0.000 0.995 0.005
Y40.7 Antifungal antibiotics, systemically used
0.000 0.995 0.004
Y40.4 Tetracyclines
0.000 0.995 0.004
Y40.2 Chloramphenicol group
0.000 0.995 0.004
Y40.3 Macrolides
0.000 0.995 0.004
Y49 Psychotropic drugs, not elsewhere classified
0.000 0.995 0.004
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.000 0.996 0.004
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.004 0.996 0.000
Y40.6 Rifamycins
0.000 0.996 0.004
Y41.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.996 0.004
Y41.4 Anthelminthics
0.000 0.996 0.004
Y41.3 Other antiprotozoal drugs
0.000 0.996 0.004
Y41.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.996 0.004
H50.9 Strabismus, unspecified
0.004 0.996 0.000
Y40.0 Penicillins
0.000 0.996 0.004
Y49.2 Other and unspecified antidepressants
0.000 0.996 0.004
Y50 Central nervous system stimulants, not elsewhere classified
0.000 0.996 0.004
Z43.2 Attention to ileostomy
0.000 0.996 0.004
Y48 Anaesthetics and therapeutic gases
0.000 0.996 0.004
K51.2 Ulcerative (chronic) proctitis
0.001 0.996 0.003
Y54.4 Loop [high-ceiling] diuretics
0.000 0.996 0.004
Y54.9 Mineral salts, not elsewhere classified
0.000 0.996 0.004
Y54.7 Agents affecting calcification
0.000 0.996 0.004
Y54.6 Electrolytic, caloric and water-balance agents
0.000 0.996 0.004
Y54.2 Carbonic-anhydrase inhibitors
0.000 0.996 0.004
Y54.0 Mineralocorticoids
0.000 0.996 0.004
Y58.0 BCG vaccine
0.000 0.996 0.004
Y59 Other and unspecified vaccines and biological substances
0.000 0.996 0.004
Y40.5 Aminoglycosides
0.000 0.996 0.004
Y54.8 Agents affecting uric acid metabolism
0.000 0.996 0.004
Z73.9 Problem related to life-management difficulty, unspecified
0.004 0.996 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.000 0.996 0.004
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.000 0.996 0.004
Y58.9 Other and unspecified bacterial vaccines
0.000 0.996 0.003
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component
0.000 0.996 0.003
Y58.6 Pertussis vaccine, including combinations with a pertussis component
0.000 0.996 0.003
Y58.5 Diphtheria vaccine
0.000 0.996 0.003
Y58.4 Tetanus vaccine
0.000 0.996 0.003
Y58.3 Plague vaccine
0.000 0.996 0.003
Y58.2 Cholera vaccine
0.000 0.996 0.003
Y58.1 Typhoid and paratyphoid vaccine
0.000 0.996 0.003
Y47 Sedatives, hypnotics and antianxiety drugs
0.000 0.996 0.003
N18.4 Chronic kidney disease, stage 4
0.000 0.996 0.004
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.996 0.003
Y49.9 Psychotropic drug, unspecified
0.000 0.996 0.003
Y49.8 Other psychotropic drugs, not elsewhere classified
0.000 0.996 0.003
Y49.7 Psychostimulants with abuse potential
0.000 0.996 0.003
Y49.6 Psychodysleptics [hallucinogens]
0.000 0.996 0.003
Y49.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.996 0.003
Y49.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.996 0.003
Y49.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.996 0.003
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.000 0.996 0.003
K52.1 Toxic gastro-enteritis and colitis
0.003 0.997 0.000
Y48.4 Anaesthetic, unspecified
0.000 0.997 0.003
Y51 Drugs primarily affecting the autonomic nervous system
0.000 0.997 0.003
Y46 Antiepileptics and anti-Parkinsonism drugs
0.000 0.997 0.003
Y40.1 Cefalosporins and other -lactam antibiotics
0.000 0.997 0.003
H50.1 Divergent concomitant strabismus
0.003 0.997 0.000
Y57 Other and unspecified drugs and medicaments
0.000 0.997 0.003
Y50.9 Central nervous system stimulant, unspecified
0.000 0.997 0.003
Y50.8 Other central nervous system stimulants
0.000 0.997 0.003
Y50.2 Methylxanthines, not elsewhere classified
0.000 0.997 0.003
Y50.1 Opioid receptor antagonists
0.000 0.997 0.003
Y50.0 Analeptics
0.000 0.997 0.003
Y53.1 Other antacids and anti-gastric-secretion drugs
0.000 0.997 0.003
Y49.0 Tricyclic and tetracyclic antidepressants
0.000 0.997 0.003
Y48.5 Therapeutic gases
0.000 0.997 0.003
Y48.1 Parenteral anaesthetics
0.000 0.997 0.003
Y48.0 Inhaled anaesthetics
0.000 0.997 0.003
G63.2 Diabetic polyneuropathy
0.000 0.997 0.003
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.997 0.003
Y48.3 Local anaesthetics
0.000 0.997 0.003
Z50.5 Speech therapy
0.000 0.997 0.003
Y53.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.997 0.003
Y59.9 Vaccine or biological substance, unspecified
0.000 0.997 0.003
Y59.8 Other specified vaccines and biological substances
0.000 0.997 0.003
Y59.2 Protozoal vaccines
0.000 0.997 0.003
Y59.1 Rickettsial vaccines
0.000 0.997 0.003
Y59.0 Viral vaccines
0.000 0.997 0.003
M54.57 Low back pain (Lumbosacral region)
0.000 0.997 0.003
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.997 0.003
Y53.7 Emetics
0.000 0.997 0.003
Y53.6 Antidiarrhoeal drugs
0.000 0.997 0.003
Y53.5 Digestants
0.000 0.997 0.003
Y53.3 Saline and osmotic laxatives
0.000 0.997 0.003
Y53.0 Histamine H2-receptor antagonists
0.000 0.997 0.003
Y48.2 Other and unspecified general anaesthetics
0.000 0.997 0.003
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.000 0.997 0.003
J69.0 Pneumonitis due to food and vomit
0.000 0.997 0.003
K66.1 Haemoperitoneum
0.003 0.997 0.000
Y40.8 Other systemic antibiotics
0.000 0.997 0.003
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.003 0.997 0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified
0.000 0.997 0.003
Y47.8 Other sedatives, hypnotics and antianxiety drugs
0.000 0.997 0.003
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified
0.000 0.997 0.003
Y47.4 Bromine compounds
0.000 0.997 0.003
Y47.3 Paraldehyde
0.000 0.997 0.003
Y47.2 Chloral derivatives
0.000 0.997 0.003
Y47.0 Barbiturates, not elsewhere classified
0.000 0.997 0.003
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.000 0.997 0.003
Y53.2 Stimulant laxatives
0.000 0.997 0.003
Y59.3 Immunoglobulin
0.000 0.997 0.003
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.000 0.997 0.003
Y54.5 Other diuretics
0.000 0.997 0.003
N45 Orchitis and epididymitis
0.003 0.997 0.000
Y49.5 Other antipsychotics and neuroleptics
0.000 0.997 0.003
Y55.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.997 0.003
Y55.5 Anticommon cold drugs
0.000 0.997 0.003
Y55.4 Expectorants
0.000 0.997 0.003
Y55.3 Antitussives
0.000 0.997 0.003
Y55.2 Other and unspecified agents primarily acting on muscles
0.000 0.997 0.003
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.997 0.003
S72.20 Subtrochanteric fracture (closed)
0.000 0.997 0.003
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.997 0.003
Y43 Primarily systemic agents
0.000 0.997 0.003
Y56.9 Topical agent, unspecified
0.000 0.997 0.003
Y56.8 Other topical agents
0.000 0.997 0.003
Y56.7 Dental drugs, topically applied
0.000 0.997 0.003
Y56.6 Otorhinolaryngological drugs and preparations
0.000 0.997 0.003
Y56.5 Ophthalmological drugs and preparations
0.000 0.997 0.003
Y56.2 Local astringents and local detergents
0.000 0.997 0.003
Y56.1 Antipruritics
0.000 0.997 0.003
Y56.3 Emollients, demulcents and protectants
0.000 0.997 0.003
Y46.8 Antispasticity drugs
0.000 0.997 0.003
Y46.5 Valproic acid
0.000 0.997 0.003
Y46.3 Deoxybarbiturates
0.000 0.997 0.003
Y46.1 Oxazolidinediones
0.000 0.997 0.003
Y46.0 Succinimides
0.000 0.997 0.003
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.997 0.003
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.997 0.003
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.997 0.003
Y51.1 Other parasympathomimetics [cholinergics]
0.000 0.997 0.003
Y51.0 Anticholinesterase agents
0.000 0.997 0.003
Y55.6 Antiasthmatics, not elsewhere classified
0.000 0.997 0.002
Y57.9 Drug or medicament, unspecified
0.000 0.997 0.003
Y57.7 Vitamins, not elsewhere classified
0.000 0.997 0.003
Y57.4 Pharmaceutical excipients
0.000 0.997 0.003
Y57.3 Alcohol deterrents
0.000 0.997 0.003
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.000 0.997 0.003
Y57.1 Lipotropic drugs
0.000 0.997 0.003
Y57.0 Appetite depressants [anorectics]
0.000 0.997 0.003
C77.8 Lymph nodes of multiple regions
0.003 0.997 0.000
Y46.7 Anti-Parkinsonism drugs
0.000 0.997 0.002
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.000 0.997 0.002
Y46.2 Hydantoin derivatives
0.000 0.997 0.002
Y44 Agents primarily affecting blood constituents
0.000 0.997 0.002
D37.1 Stomach
0.003 0.997 0.000
N18.5 Chronic kidney disease, stage 5
0.000 0.997 0.003
H52.2 Astigmatism
0.000 0.997 0.003
Y57.6 Other diagnostic agents
0.000 0.997 0.002
K66.0 Peritoneal adhesions
0.003 0.997 0.000
Y43.4 Immunosuppressive agents
0.000 0.997 0.002
Y57.8 Other drugs and medicaments
0.000 0.997 0.002
T78.1 Other adverse food reactions, not elsewhere classified
0.002 0.998 0.000
D50.8 Other iron deficiency anaemias
0.002 0.998 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.002 0.998 0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.998 0.002
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.998 0.002
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.000 0.998 0.002
Y46.4 Iminostilbenes
0.000 0.998 0.002
H53.0 Amblyopia ex anopsia
0.002 0.998 0.000
Y46.6 Other and unspecified antiepileptics
0.000 0.998 0.002
Y55.0 Oxytocic drugs
0.001 0.998 0.002
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.000 0.998 0.002
S40.0 Contusion of shoulder and upper arm
0.000 0.998 0.002
Q21.1 Atrial septal defect
0.002 0.998 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.000 0.998 0.002
H74.3 Other acquired abnormalities of ear ossicles
0.000 0.998 0.002
G43.9 Migraine, unspecified
0.002 0.998 0.000
H27.0 Aphakia
0.000 0.998 0.002
T78 Adverse effects, not elsewhere classified
0.002 0.998 0.000
Y43.9 Primarily systemic agent, unspecified
0.000 0.998 0.002
Y43.8 Other primarily systemic agents, not elsewhere classified
0.000 0.998 0.002
Y43.6 Enzymes, not elsewhere classified
0.000 0.998 0.002
Y43.5 Acidifying and alkalising agents
0.000 0.998 0.002
Y43.2 Antineoplastic natural products
0.000 0.998 0.002
Y44.5 Thrombolytic drugs
0.000 0.998 0.002
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.998 0.002
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.000 0.998 0.002
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.000 0.998 0.002
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.000 0.998 0.002
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.000 0.998 0.002
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.000 0.998 0.002
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.000 0.998 0.002
S82.10 Fracture of upper end of tibia (closed)
0.002 0.998 0.000
M80 Osteoporosis with pathological fracture
0.000 0.998 0.002
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.998 0.002
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.000 0.998 0.002
K66 Other disorders of peritoneum
0.002 0.998 0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)
0.000 0.998 0.002
Y47.1 Benzodiazepines
0.001 0.998 0.002
Y53.4 Other laxatives
0.001 0.998 0.002
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.000 0.998 0.002
J39.8 Other specified diseases of upper respiratory tract
0.000 0.998 0.002
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.000 0.998 0.002
E11.5 With peripheral circulatory complications
0.000 0.998 0.002
H27.8 Other specified disorders of lens
0.000 0.998 0.002
Q89.2 Congenital malformations of other endocrine glands
0.002 0.998 0.000
Y43.0 Antiallergic and antiemetic drugs
0.000 0.998 0.002
I27.2 Other secondary pulmonary hypertension
0.000 0.998 0.002
Y44.9 Other and unspecified agents affecting blood constituents
0.000 0.998 0.002
Y44.7 Plasma substitutes
0.000 0.998 0.002
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.000 0.998 0.002
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.000 0.998 0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.000 0.998 0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.998 0.002
K66.9 Disorder of peritoneum, unspecified
0.002 0.998 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.000 0.998 0.002
M80.0 Postmenopausal osteoporosis with pathological fracture
0.000 0.998 0.002
K72.0 Acute and subacute hepatic failure
0.000 0.998 0.002
Z46.6 Fitting and adjustment of urinary device
0.000 0.998 0.002
Y45.2 Propionic acid derivatives
0.000 0.998 0.002
Y57.5 X-ray contrast media
0.000 0.998 0.002
Y45.1 Salicylates
0.000 0.998 0.002
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.000 0.998 0.002
Y45.4 Antirheumatics
0.000 0.998 0.002
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.000 0.998 0.002
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)
0.000 0.998 0.002
Y43.1 Antineoplastic antimetabolites
0.000 0.998 0.002
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.000 0.998 0.002
J94.2 Haemothorax
0.000 0.998 0.002
M80.8 Other osteoporosis with pathological fracture
0.000 0.998 0.002
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.000 0.998 0.002
T78.9 Adverse effect, unspecified
0.002 0.998 0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.998 0.002
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.000 0.998 0.002
S72.10 Pertrochanteric fracture (closed)
0.000 0.998 0.002
D37.7 Other digestive organs
0.002 0.998 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.002 0.998 0.000
K37 Unspecified appendicitis
0.000 0.998 0.002
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.000 0.998 0.002
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.000 0.998 0.002
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.000 0.998 0.002
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.000 0.998 0.002
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.000 0.998 0.002
M80.4 Drug-induced osteoporosis with pathological fracture
0.000 0.998 0.002
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.000 0.998 0.002
M80.2 Osteoporosis of disuse with pathological fracture
0.000 0.998 0.002
Y45.0 Opioids and related analgesics
0.000 0.998 0.002
D51 Vitamin B12 deficiency anaemia
0.002 0.998 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.998 0.002
N32.3 Diverticulum of bladder
0.000 0.998 0.002
Y45.5 4-Aminophenol derivatives
0.000 0.998 0.002
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)
0.000 0.998 0.002
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)
0.000 0.998 0.002
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)
0.000 0.998 0.002
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)
0.000 0.998 0.002
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.998 0.002
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)
0.000 0.998 0.002
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)
0.000 0.998 0.002
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)
0.000 0.998 0.002
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)
0.000 0.998 0.002
M80.88 Other osteoporosis with pathological fracture (Other)
0.000 0.998 0.002
R23.8 Other and unspecified skin changes
0.000 0.998 0.002
Y44.6 Natural blood and blood products
0.000 0.998 0.001
M47.92 Spondylosis, unspecified (Cervical region)
0.000 0.998 0.002
S72.2 Subtrochanteric fracture
0.000 0.998 0.002
T78.2 Anaphylactic shock, unspecified
0.002 0.998 0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)
0.000 0.998 0.002
K52.8 Other specified non-infective gastro-enteritis and colitis
0.002 0.998 0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.000 0.998 0.001
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.000 0.998 0.002
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)
0.000 0.998 0.002
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)
0.000 0.998 0.002
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)
0.000 0.998 0.002
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)
0.000 0.998 0.002
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.998 0.002
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)
0.000 0.998 0.002
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)
0.000 0.998 0.002
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)
0.000 0.998 0.002
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)
0.000 0.998 0.002
L30.8 Other specified dermatitis
0.002 0.998 0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)
0.000 0.998 0.002
M80.58 Idiopathic osteoporosis with pathological fracture (Other)
0.000 0.998 0.002
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)
0.000 0.998 0.002
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)
0.000 0.998 0.002
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.998 0.002
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)
0.000 0.998 0.002
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)
0.000 0.998 0.002
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)
0.000 0.998 0.002
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)
0.000 0.998 0.002
R82.5 Elevated urine levels of drugs, medicaments and biological substances
0.002 0.998 0.000
R82.4 Acetonuria
0.002 0.998 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.002 0.998 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.000 0.998 0.002
T78.8 Other adverse effects, not elsewhere classified
0.002 0.998 0.000
R82 Other abnormal findings in urine
0.002 0.998 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.000 0.998 0.002
O48 Prolonged pregnancy
0.002 0.998 0.000
M25.59 Pain in joint (Site unspecified)
0.000 0.998 0.002
M80.89 Other osteoporosis with pathological fracture (Site unspecified)
0.000 0.998 0.001
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)
0.000 0.998 0.001
M80.86 Other osteoporosis with pathological fracture (Lower leg)
0.000 0.998 0.001
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.998 0.001
M80.84 Other osteoporosis with pathological fracture (Hand)
0.000 0.998 0.001
M80.83 Other osteoporosis with pathological fracture (Forearm)
0.000 0.998 0.001
M80.82 Other osteoporosis with pathological fracture (Upper arm)
0.000 0.998 0.001
M80.80 Other osteoporosis with pathological fracture (Multiple sites)
0.000 0.998 0.001
D51.3 Other dietary vitamin B12 deficiency anaemia
0.002 0.998 0.000
T92.0 Sequelae of open wound of upper limb
0.002 0.998 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.002 0.998 0.000
I78.1 Naevus, nonneoplastic
0.000 0.998 0.002
S05.1 Contusion of eyeball and orbital tissues
0.000 0.998 0.002
H27 Other disorders of lens
0.000 0.998 0.002
R82.1 Myoglobinuria
0.002 0.998 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.000 0.998 0.002
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)
0.000 0.998 0.001
M80.28 Osteoporosis of disuse with pathological fracture (Other)
0.000 0.998 0.001
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)
0.000 0.998 0.001
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)
0.000 0.998 0.001
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)
0.000 0.998 0.001
M80.24 Osteoporosis of disuse with pathological fracture (Hand)
0.000 0.998 0.001
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)
0.000 0.998 0.001
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)
0.000 0.998 0.001
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)
0.000 0.998 0.001
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)
0.000 0.998 0.001
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)
0.000 0.998 0.001
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)
0.000 0.998 0.001
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)
0.000 0.998 0.001
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)
0.000 0.998 0.001
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.998 0.001
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)
0.000 0.998 0.001
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)
0.000 0.998 0.001
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)
0.000 0.998 0.001
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)
0.000 0.998 0.001
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)
0.000 0.998 0.001
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)
0.000 0.998 0.001
M80.48 Drug-induced osteoporosis with pathological fracture (Other)
0.000 0.998 0.001
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)
0.000 0.998 0.001
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)
0.000 0.998 0.001
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.998 0.001
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)
0.000 0.998 0.001
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)
0.000 0.998 0.001
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)
0.000 0.998 0.001
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)
0.000 0.998 0.001
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)
0.000 0.998 0.001
D51.8 Other vitamin B12 deficiency anaemias
0.001 0.998 0.000
D51.2 Transcobalamin II deficiency
0.001 0.998 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.001 0.998 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.000 0.998 0.001
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.002 0.998 0.000
R82.9 Other and unspecified abnormal finding in urine
0.002 0.998 0.000
R82.7 Abnormal findings on microbiological examination of urine
0.002 0.998 0.000
Y44.2 Anticoagulants
0.000 0.998 0.001
J69 Pneumonitis due to solids and liquids
0.000 0.998 0.002
S72.21 Subtrochanteric fracture (open)
0.000 0.998 0.001
R82.8 Abnormal findings on cytological and histological examination of urine
0.002 0.998 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.002 0.998 0.000
E16.2 Hypoglycaemia, unspecified
0.002 0.998 0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand
0.000 0.998 0.002
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.002 0.998 0.000
Q21 Congenital malformations of cardiac septa
0.002 0.998 0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)
0.000 0.998 0.001
D37.2 Small intestine
0.001 0.998 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.000 0.998 0.002
I27.8 Other specified pulmonary heart diseases
0.000 0.998 0.001
Q21.3 Tetralogy of Fallot
0.001 0.998 0.000
T87.4 Infection of amputation stump
0.000 0.998 0.001
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.002 0.998 0.000
H51 Other disorders of binocular movement
0.001 0.998 0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.000 0.998 0.001
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)
0.000 0.998 0.001
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)
0.000 0.998 0.001
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)
0.000 0.998 0.001
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)
0.000 0.998 0.001
S02.00 Fracture of vault of skull (closed)
0.000 0.998 0.001
M35.3 Polymyalgia rheumatica
0.000 0.998 0.002
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source
0.001 0.998 0.000
R82.3 Haemoglobinuria
0.001 0.998 0.000
R82.2 Biliuria
0.001 0.998 0.000
R82.0 Chyluria
0.001 0.998 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.000 0.998 0.001
D37.3 Appendix
0.001 0.998 0.000
H51.2 Internuclear ophthalmoplegia
0.001 0.998 0.000
I27.9 Pulmonary heart disease, unspecified
0.000 0.998 0.001
T31.0 Burns involving less than 10% of body surface
0.000 0.998 0.001
Y45.8 Other analgesics and antipyretics
0.000 0.998 0.001
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.998 0.001
Q89 Other congenital malformations, not elsewhere classified
0.001 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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