TreeWAS – Variant ID: rs17228178

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M48.00 Spinal stenosis (Multiple sites in spine)	0.028	0.972	0.000
M48.0 Spinal stenosis	0.024	0.976	0.000
E10.3 With ophthalmic complications	0.023	0.977	0.000
E10 Insulin-dependent diabetes mellitus	0.023	0.977	0.000
E10.5 With peripheral circulatory complications	0.022	0.978	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.021	0.979	0.000
E10.4 With neurological complications	0.020	0.980	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.020	0.980	0.000
M48.02 Spinal stenosis (Cervical region)	0.020	0.980	0.000
E10.6 With other specified complications	0.020	0.980	0.000
M48.04 Spinal stenosis (Thoracic region)	0.019	0.981	0.000
E10.1 With ketoacidosis	0.019	0.981	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.017	0.983	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.017	0.983	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.017	0.983	0.000
E10.8 With unspecified complications	0.017	0.983	0.000
E10.2 With renal complications	0.016	0.983	0.000
E10.7 With multiple complications	0.016	0.984	0.000
E10.0 With coma	0.015	0.985	0.000
M48.06 Spinal stenosis (Lumbar region)	0.015	0.985	0.000
E10.9 Without complications	0.015	0.985	0.000
I44.7 Left bundle-branch block, unspecified	0.014	0.986	0.000
M48 Other spondylopathies	0.014	0.986	0.000
M48.9 Spondylopathy, unspecified	0.012	0.988	0.000
M48.8 Other specified spondylopathies	0.012	0.988	0.000
M48.09 Spinal stenosis (Site unspecified)	0.011	0.989	0.000
M48.4 Fatigue fracture of vertebra	0.010	0.990	0.000
M48.3 Traumatic spondylopathy	0.010	0.990	0.000
M48.2 Kissing spine	0.010	0.990	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.010	0.990	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.010	0.990	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.009	0.990	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.009	0.990	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.009	0.991	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.009	0.991	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.009	0.991	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.009	0.991	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.009	0.991	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.009	0.991	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.009	0.991	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.009	0.991	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.009	0.991	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.009	0.991	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.008	0.991	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.008	0.991	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.008	0.991	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.008	0.991	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.008	0.991	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.008	0.991	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.008	0.991	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.008	0.991	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.008	0.992	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.008	0.992	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.008	0.992	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.008	0.992	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.008	0.992	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.008	0.992	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.008	0.992	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.008	0.992	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.008	0.992	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.008	0.992	0.000
M48.29 Kissing spine (Site unspecified)	0.008	0.992	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.008	0.992	0.000
M48.27 Kissing spine (Lumbosacral region)	0.008	0.992	0.000
M48.26 Kissing spine (Lumbar region)	0.008	0.992	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.008	0.992	0.000
M48.24 Kissing spine (Thoracic region)	0.008	0.992	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.008	0.992	0.000
M48.22 Kissing spine (Cervical region)	0.008	0.992	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.008	0.992	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.008	0.992	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.008	0.992	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.008	0.992	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.008	0.992	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.008	0.992	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.008	0.992	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.008	0.992	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.008	0.992	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.008	0.992	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.008	0.992	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.008	0.992	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.008	0.992	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.008	0.992	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.008	0.992	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.008	0.992	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.008	0.992	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.008	0.992	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.008	0.992	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.008	0.992	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.008	0.992	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.008	0.992	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.992	0.008
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.007	0.993	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.007	0.993	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.007	0.993	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.007	0.993	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.007	0.993	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.007	0.993	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.007	0.993	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.007	0.993	0.000
Z09.0 Follow-up examination after surgery for other conditions	0.000	0.994	0.006
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.006	0.994	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.995	0.005
K86.3 Pseudocyst of pancreas	0.000	0.995	0.005
H90.5 Sensorineural hearing loss, unspecified	0.005	0.995	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.995	0.005
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.004	0.995	0.000
K86.2 Cyst of pancreas	0.000	0.995	0.005
K86 Other diseases of pancreas	0.000	0.995	0.005
R68.8 Other specified general symptoms and signs	0.000	0.996	0.004
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.996	0.004
N94.6 Dysmenorrhoea, unspecified	0.000	0.996	0.004
K86.8 Other specified diseases of pancreas	0.000	0.996	0.004
H02.1 Ectropion of eyelid	0.000	0.996	0.004
T78.8 Other adverse effects, not elsewhere classified	0.000	0.996	0.004
I44 Atrioventricular and left bundle-branch block	0.004	0.996	0.000
T78.9 Adverse effect, unspecified	0.000	0.996	0.004
K86.9 Disease of pancreas, unspecified	0.000	0.996	0.004
T78.3 Angioneurotic oedema	0.000	0.996	0.004
I44.6 Other and unspecified fascicular block	0.004	0.996	0.000
I44.2 Atrioventricular block, complete	0.003	0.997	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.003	0.997	0.000
I44.5 Left posterior fascicular block	0.003	0.997	0.000
Y53.4 Other laxatives	0.003	0.997	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.003	0.997	0.000
S62.61 Fracture of other finger (open)	0.003	0.997	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.997	0.003
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.003	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.003	0.997	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.997	0.003
Y53.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
I44.4 Left anterior fascicular block	0.003	0.997	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.003	0.997	0.000
Y41.5 Antiviral drugs	0.003	0.997	0.000
A04.5 Campylobacter enteritis	0.003	0.997	0.000
R44.3 Hallucinations, unspecified	0.003	0.997	0.000
I44.1 Atrioventricular block, second degree	0.003	0.997	0.000
I44.3 Other and unspecified atrioventricular block	0.002	0.997	0.000
I49.1 Atrial premature depolarisation	0.000	0.997	0.003
T78.4 Allergy, unspecified	0.000	0.997	0.002
M86.6 Other chronic osteomyelitis	0.002	0.998	0.000
K86.1 Other chronic pancreatitis	0.000	0.998	0.002
D84 Other immunodeficiencies	0.002	0.998	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.998	0.002
R44.0 Auditory hallucinations	0.002	0.998	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
J30.4 Allergic rhinitis, unspecified	0.000	0.998	0.002
R82.7 Abnormal findings on microbiological examination of urine	0.000	0.998	0.002
Y40.0 Penicillins	0.002	0.998	0.000
C34.3 Lower lobe, bronchus or lung	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
I49.3 Ventricular premature depolarisation	0.000	0.998	0.002
R44 Other symptoms and signs involving general sensations and perceptions	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.998	0.002
W02.9 Unspecified place	0.000	0.998	0.002
D86 Sarcoidosis	0.002	0.998	0.000
R68 Other general symptoms and signs	0.000	0.998	0.002
M47.86 Other spondylosis (Lumbar region)	0.002	0.998	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.998	0.002
M86.69 Other chronic osteomyelitis (Site unspecified)	0.002	0.998	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.998	0.002
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.998	0.002
I49.4 Other and unspecified premature depolarisation	0.000	0.998	0.002
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
K90.9 Intestinal malabsorption, unspecified	0.000	0.998	0.002
Y40.4 Tetracyclines	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
F17.2 Dependence syndrome	0.002	0.998	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.002	0.998	0.000
Q85.9 Phakomatosis, unspecified	0.002	0.998	0.000
R68.0 Hypothermia, not associated with low environmental temperature	0.000	0.998	0.002
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M86.66 Other chronic osteomyelitis (Lower leg)	0.002	0.998	0.000
R82.4 Acetonuria	0.000	0.998	0.002
M86.68 Other chronic osteomyelitis (Other)	0.002	0.998	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.002	0.998	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.002	0.998	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
R82 Other abnormal findings in urine	0.000	0.998	0.002
T66-T78 Other and unspecified effects of external causes	0.000	0.998	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
R82.9 Other and unspecified abnormal finding in urine	0.000	0.998	0.002
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
T66 Unspecified effects of radiation	0.000	0.998	0.002
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
M45-M49 Spondylopathies	0.002	0.998	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
I49 Other cardiac arrhythmias	0.000	0.998	0.002
T71 Asphyxiation	0.000	0.998	0.002
C92.0 Acute myeloid leukaemia	0.000	0.998	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
R68.1 Nonspecific symptoms peculiar to infancy	0.000	0.998	0.002
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
R44.2 Other hallucinations	0.002	0.998	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.998	0.002
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
M79.2 Neuralgia and neuritis, unspecified	0.002	0.998	0.000
B16 Acute hepatitis B	0.000	0.998	0.002
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
K05.3 Chronic periodontitis	0.002	0.998	0.000
K05.1 Chronic gingivitis	0.002	0.998	0.000
R68.3 Clubbing of fingers	0.000	0.998	0.002
Q76.0 Spina bifida occulta	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
B19.9 Unspecified viral hepatitis without coma	0.000	0.998	0.002
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.002	0.998	0.000
Q82.5 Congenital nonneoplastic naevus	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
T70 Effects of air pressure and water pressure	0.000	0.998	0.002
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.002	0.998	0.000
C32.0 Glottis	0.002	0.998	0.000
I73.0 Raynaud's syndrome	0.000	0.998	0.002
M45 Ankylosing spondylitis	0.002	0.998	0.000
C69.3 Choroid	0.000	0.998	0.002
H53.9 Visual disturbance, unspecified	0.000	0.998	0.002
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.000	0.998	0.002
R82.3 Haemoglobinuria	0.000	0.998	0.002
R82.2 Biliuria	0.000	0.998	0.002
R82.0 Chyluria	0.000	0.998	0.002
T74 Maltreatment syndromes	0.000	0.998	0.002
T73 Effects of other deprivation	0.000	0.998	0.002
T69 Other effects of reduced temperature	0.000	0.998	0.002
T67 Effects of heat and light	0.000	0.998	0.002
R68.2 Dry mouth, unspecified	0.000	0.998	0.002
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
I49.0 Ventricular fibrillation and flutter	0.000	0.998	0.002
M45.X9 Ankylosing spondylitis (Site unspecified)	0.002	0.998	0.000
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
B17.1 Acute hepatitis C	0.000	0.998	0.002
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T75 Effects of other external causes	0.000	0.998	0.002
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
I49.2 Junctional premature depolarisation	0.000	0.998	0.002
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.000	0.998	0.001
S27.0 Traumatic pneumothorax	0.000	0.998	0.002
D81 Combined immunodeficiencies	0.001	0.998	0.000
K05.6 Periodontal disease, unspecified	0.002	0.998	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.998	0.002
B19 Unspecified viral hepatitis	0.000	0.998	0.002
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.001	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.998	0.000
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
K05 Gingivitis and periodontal diseases	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.001	0.998	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.001	0.998	0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.001	0.998	0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.001	0.998	0.000
A49.8 Other bacterial infections of unspecified site	0.000	0.998	0.002
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.000	0.998	0.001
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.000	0.998	0.001
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.000	0.998	0.001
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.998	0.000
D86.3 Sarcoidosis of skin	0.001	0.998	0.000
Q85.1 Tuberous sclerosis	0.001	0.998	0.000
Q05 Spina bifida	0.002	0.998	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.001	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
C69.9 Eye, unspecified	0.000	0.998	0.002
K61.0 Anal abscess	0.000	0.998	0.002
Q76.9 Congenital malformation of bony thorax, unspecified	0.001	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.001	0.998	0.000
Q76.7 Congenital malformation of sternum	0.001	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.001	0.998	0.000
Q76.5 Cervical rib	0.001	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.001	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.001	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.001	0.998	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.998	0.002
Y48.4 Anaesthetic, unspecified	0.001	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.001	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.998	0.000
K05.5 Other periodontal diseases	0.001	0.998	0.000
O62.3 Precipitate labour	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.001	0.998	0.000
S27.2 Traumatic heamopneumothorax	0.000	0.998	0.001
T70.3 Caisson disease [decompression sickness]	0.000	0.998	0.001
Z89.6 Acquired absence of leg above knee	0.000	0.998	0.002
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.001	0.998	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.998	0.002
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.001	0.998	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.001	0.998	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.001	0.998	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.001	0.998	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.001	0.998	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.001	0.998	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.001	0.998	0.000
T70.9 Effect of air pressure and water pressure, unspecified	0.000	0.998	0.001
T70.8 Other effects of air pressure and water pressure	0.000	0.998	0.001
T70.4 Effects of high-pressure fluids	0.000	0.998	0.001
T70.2 Other and unspecified effects of high altitude	0.000	0.998	0.001
T70.1 Sinus barotrauma	0.000	0.998	0.001
T70.0 Otitic barotrauma	0.000	0.998	0.001
B17 Other acute viral hepatitis	0.000	0.998	0.001
T67.9 Effects of heat and light, unspecified	0.000	0.998	0.001
T67.8 Other effects of heat and light	0.000	0.998	0.001
T67.7 Heat oedema	0.000	0.998	0.001
T67.6 Heat fatigue, transient	0.000	0.998	0.001
T67.5 Heat exhaustion, unspecified	0.000	0.998	0.001
T67.4 Heat exhaustion due to salt depletion	0.000	0.998	0.001
T67.3 Heat exhaustion, anhydrotic	0.000	0.998	0.001
T67.2 Heat cramp	0.000	0.998	0.001
T67.1 Heat syncope	0.000	0.998	0.001
T67.0 Heatstroke and sunstroke	0.000	0.998	0.001
T69.9 Effect of reduced temperature, unspecified	0.000	0.998	0.001
T69.8 Other specified effects of reduced temperature	0.000	0.998	0.001
T69.1 Chilblains	0.000	0.998	0.001
T69.0 Immersion hand and foot	0.000	0.998	0.001
T73.9 Effect of deprivation, unspecified	0.000	0.998	0.001
T73.8 Other effects of deprivation	0.000	0.998	0.001
T73.3 Exhaustion due to excessive exertion	0.000	0.998	0.001
T73.2 Exhaustion due to exposure	0.000	0.998	0.001
T73.1 Effects of thirst	0.000	0.998	0.001
T73.0 Effects of hunger	0.000	0.998	0.001
T74.9 Maltreatment syndrome, unspecified	0.000	0.998	0.001
T74.8 Other maltreatment syndromes	0.000	0.998	0.001
T74.3 Psychological abuse	0.000	0.998	0.001
T74.2 Sexual abuse	0.000	0.998	0.001
T74.1 Physical abuse	0.000	0.998	0.001
T74.0 Neglect or abandonment	0.000	0.998	0.001
Y49.2 Other and unspecified antidepressants	0.001	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.001	0.998	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.998	0.001
M79.28 Neuralgia and neuritis, unspecified (Other)	0.001	0.998	0.000
G93.6 Cerebral oedema	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.001	0.998	0.000
R82.1 Myoglobinuria	0.000	0.998	0.001
Y48.5 Therapeutic gases	0.001	0.998	0.000
Y48.1 Parenteral anaesthetics	0.001	0.998	0.000
Y48.0 Inhaled anaesthetics	0.001	0.998	0.000
Y57.8 Other drugs and medicaments	0.001	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.001	0.998	0.000
Q65.9 Congenital deformity of hip, unspecified	0.001	0.998	0.000
Q65.6 Unstable hip	0.001	0.998	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.001	0.998	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.001	0.998	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.001	0.998	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.001	0.998	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.001	0.998	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.001	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
Q78 Other osteochondrodysplasias	0.001	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.001	0.998	0.000
Q82.9 Congenital malformation of skin, unspecified	0.001	0.999	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.001	0.999	0.000
Q82.3 Incontinentia pigmenti	0.001	0.999	0.000
Q82.1 Xeroderma pigmentosum	0.001	0.999	0.000
X10.0 Home	0.001	0.999	0.000
Y46.6 Other and unspecified antiepileptics	0.001	0.999	0.000
Y58 Bacterial vaccines	0.001	0.999	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.001	0.999	0.000
B15-B19 Viral hepatitis	0.000	0.999	0.001
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.001	0.999	0.000
I49.8 Other specified cardiac arrhythmias	0.000	0.999	0.001
M45.X2 Ankylosing spondylitis (Cervical region)	0.001	0.999	0.000
T75.8 Other specified effects of external causes	0.000	0.999	0.001
T75.3 Motion sickness	0.000	0.999	0.001
T75.2 Effects of vibration	0.000	0.999	0.001
T75.0 Effects of lightning	0.000	0.999	0.001
Y49.9 Psychotropic drug, unspecified	0.001	0.999	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.999	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.999	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.999	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.999	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.999	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
Z83.5 Family history of eye and ear disorders	0.000	0.999	0.001
B18 Chronic viral hepatitis	0.000	0.999	0.001
D83 Common variable immunodeficiency	0.001	0.999	0.000
M49 Spondylopathies in diseases classified elsewhere	0.001	0.999	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.999	0.001
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000
D81.8 Other combined immunodeficiencies	0.001	0.999	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.000
D81.4 Nezelof's syndrome	0.001	0.999	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.001	0.999	0.000
T75.4 Effects of electric current	0.000	0.999	0.001
B19.0 Unspecified viral hepatitis with coma	0.000	0.999	0.001
D86.9 Sarcoidosis, unspecified	0.001	0.999	0.000
Q67.6 Pectus excavatum	0.001	0.999	0.000
Y46.8 Antispasticity drugs	0.001	0.999	0.000
Y46.5 Valproic acid	0.001	0.999	0.000
Y46.3 Deoxybarbiturates	0.001	0.999	0.000
Y46.2 Hydantoin derivatives	0.001	0.999	0.000
Y46.1 Oxazolidinediones	0.001	0.999	0.000
Y46.0 Succinimides	0.001	0.999	0.000
K05.2 Acute periodontitis	0.001	0.999	0.000
K05.4 Periodontosis	0.001	0.999	0.000
N94.1 Dyspareunia	0.000	0.999	0.001
Q05.8 Sacral spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.001	0.999	0.000
Q31.0 Web of larynx	0.001	0.999	0.000
R80 Isolated proteinuria	0.000	0.999	0.001
B18.2 Chronic viral hepatitis C	0.000	0.999	0.001
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.999	0.000
Y55.5 Anticommon cold drugs	0.001	0.999	0.000
Y55.4 Expectorants	0.001	0.999	0.000
Y55.3 Antitussives	0.001	0.999	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.001	0.999	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.999	0.000
Y55.0 Oxytocic drugs	0.001	0.999	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.001	0.999	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.999	0.001
K05.0 Acute gingivitis	0.001	0.999	0.000
Q82.0 Hereditary lymphoedema	0.001	0.999	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
Q89 Other congenital malformations, not elsewhere classified	0.001	0.999	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.001	0.999	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.999	0.001
B17.9 Acute viral hepatitis, unspecified	0.000	0.999	0.001
B17.2 Acute hepatitis E	0.000	0.999	0.001
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.000	0.999	0.001
T75.1 Drowning and nonfatal submersion	0.000	0.999	0.001
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.999	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.001	0.999	0.000
H31.0 Chorioretinal scars	0.000	0.999	0.001
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.999	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.999	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.001	0.999	0.000
Y51.0 Anticholinesterase agents	0.001	0.999	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.001	0.999	0.000
Q84 Other congenital malformations of integument	0.001	0.999	0.000
Q81 Epidermolysis bullosa	0.001	0.999	0.000
Q80 Congenital ichthyosis	0.001	0.999	0.000
Y59 Other and unspecified vaccines and biological substances	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations