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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17419851
log Bayes Factor = 0.144152
Chromosome 6   position 24,749,413  (GRCh37) Explore rs17419851 on Ensembl!
Variant rs17419851 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I49 Other cardiac arrhythmias
0.301 0.699 0.000
I42 Cardiomyopathy
0.300 0.700 0.000
I49.4 Other and unspecified premature depolarisation
0.300 0.700 0.000
I30-I52 Other forms of heart disease
0.299 0.701 0.000
I47 Paroxysmal tachycardia
0.294 0.706 0.000
I44 Atrioventricular and left bundle-branch block
0.292 0.708 0.000
I44.1 Atrioventricular block, second degree
0.288 0.712 0.000
I47.1 Supraventricular tachycardia
0.288 0.712 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.278 0.722 0.000
I42.9 Cardiomyopathy, unspecified
0.276 0.724 0.000
I49.8 Other specified cardiac arrhythmias
0.273 0.727 0.000
I38 Endocarditis, valve unspecified
0.268 0.732 0.000
I42.0 Dilated cardiomyopathy
0.262 0.738 0.000
I44.0 Atrioventricular block, first degree
0.255 0.745 0.000
I42.2 Other hypertrophic cardiomyopathy
0.248 0.752 0.000
I49.3 Ventricular premature depolarisation
0.248 0.752 0.000
I49.1 Atrial premature depolarisation
0.248 0.752 0.000
I30 Acute pericarditis
0.247 0.753 0.000
I45 Other conduction disorders
0.243 0.757 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.238 0.762 0.000
I40 Acute myocarditis
0.228 0.772 0.000
I45.9 Conduction disorder, unspecified
0.226 0.774 0.000
I42.6 Alcoholic cardiomyopathy
0.225 0.775 0.000
I44.3 Other and unspecified atrioventricular block
0.220 0.780 0.000
I47.2 Ventricular tachycardia
0.220 0.780 0.000
I45.2 Bifascicular block
0.220 0.780 0.000
I44.2 Atrioventricular block, complete
0.216 0.784 0.000
I49.5 Sick sinus syndrome
0.216 0.784 0.000
I49.2 Junctional premature depolarisation
0.216 0.784 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.215 0.785 0.000
I42.5 Other restrictive cardiomyopathy
0.215 0.785 0.000
I42.4 Endocardial fibroelastosis
0.215 0.785 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.215 0.785 0.000
I52 Other heart disorders in diseases classified elsewhere
0.215 0.785 0.000
I48 Atrial fibrillation and flutter
0.215 0.785 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.215 0.785 0.000
I41 Myocarditis in diseases classified elsewhere
0.215 0.785 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.215 0.785 0.000
I32 Pericarditis in diseases classified elsewhere
0.215 0.785 0.000
I44.5 Left posterior fascicular block
0.209 0.791 0.000
I44.4 Left anterior fascicular block
0.209 0.791 0.000
I36 Nonrheumatic tricuspid valve disorders
0.206 0.794 0.000
I37 Pulmonary valve disorders
0.202 0.797 0.000
I47.0 Reentry ventricular arrhythmia
0.201 0.799 0.000
I44.6 Other and unspecified fascicular block
0.201 0.799 0.000
I30.1 Infective pericarditis
0.199 0.801 0.000
I30.9 Acute pericarditis, unspecified
0.192 0.808 0.000
I45.4 Nonspecific intraventricular block
0.188 0.812 0.000
I51 Complications and ill-defined descriptions of heart disease
0.181 0.819 0.000
I49.0 Ventricular fibrillation and flutter
0.178 0.822 0.000
I42.8 Other cardiomyopathies
0.177 0.823 0.000
I30.8 Other forms of acute pericarditis
0.177 0.823 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.177 0.823 0.000
I40.0 Infective myocarditis
0.176 0.824 0.000
I45.0 Right fascicular block
0.174 0.826 0.000
I33 Acute and subacute endocarditis
0.173 0.827 0.000
I51.0 Cardiac septal defect, acquired
0.169 0.831 0.000
I45.8 Other specified conduction disorders
0.166 0.834 0.000
I45.5 Other specified heart block
0.165 0.835 0.000
I40.9 Acute myocarditis, unspecified
0.163 0.837 0.000
I40.8 Other acute myocarditis
0.163 0.837 0.000
I40.1 Isolated myocarditis
0.163 0.837 0.000
I51.8 Other ill-defined heart diseases
0.156 0.844 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.154 0.846 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.154 0.846 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.154 0.846 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.154 0.846 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.154 0.846 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.154 0.846 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.154 0.846 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.154 0.846 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.154 0.846 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.154 0.846 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.154 0.846 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.154 0.846 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.154 0.846 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.154 0.846 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.154 0.846 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.154 0.846 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.154 0.846 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.154 0.846 0.000
I48.4 Atypical atrial flutter
0.154 0.846 0.000
I48.3 Typical atrial flutter
0.154 0.846 0.000
I48.2 Chronic atrial fibrillation
0.154 0.846 0.000
I48.1 Persistent atrial fibrillation
0.154 0.846 0.000
I48.0 Paroxysmal atrial fibrillation
0.154 0.846 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.154 0.846 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.154 0.846 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.154 0.846 0.000
I45.3 Trifascicular block
0.154 0.846 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.148 0.852 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.148 0.852 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.148 0.852 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.148 0.852 0.000
I37.9 Pulmonary valve disorder, unspecified
0.145 0.855 0.000
I37.8 Other pulmonary valve disorders
0.145 0.855 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.145 0.855 0.000
I37.0 Pulmonary valve stenosis
0.145 0.855 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.139 0.861 0.000
I46 Cardiac arrest
0.135 0.865 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.135 0.865 0.000
I37.1 Pulmonary valve insufficiency
0.133 0.867 0.000
I51.5 Myocardial degeneration
0.130 0.870 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.130 0.870 0.000
I51.6 Cardiovascular disease, unspecified
0.126 0.874 0.000
I33.9 Acute endocarditis, unspecified
0.124 0.876 0.000
I45.6 Preexcitation syndrome
0.122 0.878 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.113 0.887 0.000
I35 Nonrheumatic aortic valve disorders
0.109 0.891 0.000
I51.9 Heart disease, unspecified
0.098 0.902 0.000
I35.8 Other aortic valve disorders
0.097 0.903 0.000
I46.1 Sudden cardiac death, so described
0.097 0.903 0.000
I49.9 Cardiac arrhythmia, unspecified
0.093 0.907 0.000
I51.4 Myocarditis, unspecified
0.083 0.916 0.000
I46.9 Cardiac arrest, unspecified
0.082 0.917 0.000
I33.0 Acute and subacute infective endocarditis
0.082 0.918 0.000
I31 Other diseases of pericardium
0.082 0.918 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.065 0.935 0.000
I34 Nonrheumatic mitral valve disorders
0.060 0.939 0.000
I35.1 Aortic (valve) insufficiency
0.060 0.940 0.000
I31.8 Other specified diseases of pericardium
0.059 0.941 0.000
I31.2 Haemopericardium, not elsewhere classified
0.059 0.941 0.000
I31.1 Chronic constrictive pericarditis
0.059 0.941 0.000
I31.0 Chronic adhesive pericarditis
0.059 0.941 0.000
I35.9 Aortic valve disorder, unspecified
0.053 0.947 0.000
I46.0 Cardiac arrest with successful resuscitation
0.050 0.950 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.046 0.954 0.000
I44.7 Left bundle-branch block, unspecified
0.046 0.954 0.000
I45.1 Other and unspecified right bundle-branch block
0.045 0.955 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.043 0.956 0.000
E14.9 Without complications
0.043 0.957 0.000
E14 Unspecified diabetes mellitus
0.042 0.958 0.000
I50 Heart failure
0.042 0.958 0.000
E14.3 With ophthalmic complications
0.041 0.959 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.038 0.961 0.000
E10.9 Without complications
0.037 0.963 0.000
E10 Insulin-dependent diabetes mellitus
0.037 0.963 0.000
E10-E14 Diabetes mellitus
0.035 0.965 0.000
E10.1 With ketoacidosis
0.033 0.967 0.000
E10.8 With unspecified complications
0.032 0.968 0.000
E10.5 With peripheral circulatory complications
0.031 0.969 0.000
E14.1 With ketoacidosis
0.031 0.969 0.000
E14.8 With unspecified complications
0.030 0.969 0.000
E14.7 With multiple complications
0.030 0.969 0.000
E14.6 With other specified complications
0.030 0.969 0.000
E14.5 With peripheral circulatory complications
0.030 0.969 0.000
E14.4 With neurological complications
0.030 0.969 0.000
E14.2 Withrenal complications
0.030 0.969 0.000
E14.0 With coma
0.030 0.969 0.000
E10.6 With other specified complications
0.029 0.971 0.000
I35.0 Aortic (valve) stenosis
0.028 0.972 0.000
E10.7 With multiple complications
0.027 0.973 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.026 0.974 0.000
E10.0 With coma
0.025 0.974 0.000
E12 Malnutrition-related diabetes mellitus
0.025 0.975 0.000
I31.3 Pericardial effusion (noninflammatory)
0.024 0.975 0.000
E10.4 With neurological complications
0.024 0.976 0.000
I50.9 Heart failure, unspecified
0.022 0.978 0.000
E13 Other specified diabetes mellitus
0.021 0.978 0.000
E10.2 With renal complications
0.021 0.978 0.000
I31.9 Disease of pericardium, unspecified
0.019 0.980 0.001
E12.9 Without complications
0.018 0.982 0.000
E12.8 With unspecified complications
0.018 0.982 0.000
E12.7 With multiple complications
0.018 0.982 0.000
E12.6 With other specified complications
0.018 0.982 0.000
E12.5 With peripheral circulatory complications
0.018 0.982 0.000
E12.4 With neurological complications
0.018 0.982 0.000
E12.3 With ophthalmic complications
0.018 0.982 0.000
E12.2 With renal complications
0.018 0.982 0.000
E12.1 With ketoacidosis
0.018 0.982 0.000
E12.0 With coma
0.018 0.982 0.000
E10.3 With ophthalmic complications
0.017 0.983 0.000
G47.9 Sleep disorder, unspecified
0.016 0.984 0.000
E13.8 With unspecified complications
0.015 0.984 0.000
E13.7 With multiple complications
0.015 0.984 0.000
E13.6 With other specified complications
0.015 0.984 0.000
E13.5 With peripheral circulatory complications
0.015 0.984 0.000
E13.4 With neurological complications
0.015 0.984 0.000
E13.3 With ophthalmic complications
0.015 0.984 0.000
E13.2 With renal complications
0.015 0.984 0.000
E13.1 With ketoacidosis
0.015 0.984 0.000
E13.0 With coma
0.015 0.984 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.015 0.985 0.000
E50-E64 Other nutritional deficiencies
0.015 0.985 0.000
E22 Hyperfunction of pituitary gland
0.013 0.987 0.000
E55 Vitamin D deficiency
0.013 0.987 0.000
E20-E35 Disorders of other endocrine glands
0.013 0.987 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.013 0.987 0.000
E61 Deficiency of other nutrient elements
0.013 0.987 0.000
E55.9 Vitamin D deficiency, unspecified
0.012 0.988 0.000
E06.3 Autoimmune thyroiditis
0.012 0.988 0.000
I34.1 Mitral (valve) prolapse
0.012 0.988 0.001
E00-E07 Disorders of thyroid gland
0.012 0.988 0.000
E13.9 Without complications
0.012 0.988 0.000
E06 Thyroiditis
0.012 0.988 0.000
E22.0 Acromegaly and pituitary gigantism
0.011 0.989 0.000
M54.9 Dorsalgia, unspecified
0.011 0.989 0.000
E61.1 Iron deficiency
0.011 0.989 0.000
E34 Other endocrine disorders
0.011 0.989 0.000
E26 Hyperaldosteronism
0.011 0.989 0.000
E40-E46 Malnutrition
0.011 0.989 0.000
E65-E68 Obesity and other hyperalimentation
0.011 0.989 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.011 0.989 0.000
E63 Other nutritional deficiencies
0.011 0.989 0.000
E56 Other vitamin deficiencies
0.011 0.989 0.000
E51 Thiamine deficiency
0.011 0.989 0.000
E50 Vitamin A deficiency
0.011 0.989 0.000
E60 Dietary zinc deficiency
0.011 0.989 0.000
E59 Dietary selenium deficiency
0.011 0.989 0.000
E58 Dietary calcium deficiency
0.011 0.989 0.000
E54 Ascorbic acid deficiency
0.011 0.989 0.000
E52 Niacin deficiency [pellagra]
0.011 0.989 0.000
G47 Sleep disorders
0.011 0.989 0.000
E07 Other disorders of thyroid
0.010 0.989 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.010 0.990 0.000
E53 Deficiency of other B group vitamins
0.010 0.990 0.000
E22.1 Hyperprolactinaemia
0.010 0.990 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.010 0.990 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.010 0.990 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.010 0.990 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.010 0.990 0.000
E22.8 Other hyperfunction of pituitary gland
0.010 0.990 0.000
E55.0 Rickets, active
0.010 0.990 0.000
E04.1 Non-toxic single thyroid nodule
0.010 0.990 0.000
E26.0 Primary hyperaldosteronism
0.010 0.990 0.000
E34.9 Endocrine disorder, unspecified
0.010 0.990 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.009 0.990 0.000
E32 Diseases of thymus
0.009 0.990 0.000
E31 Polyglandular dysfunction
0.009 0.990 0.000
E30 Disorders of puberty, not elsewhere classified
0.009 0.990 0.000
E25 Adrenogenital disorders
0.009 0.990 0.000
E20 Hypoparathyroidism
0.009 0.990 0.000
E61.2 Magnesium deficiency
0.009 0.990 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.009 0.991 0.000
E21.2 Other hyperparathyroidism
0.009 0.991 0.000
E65 Localised adiposity
0.009 0.991 0.000
E61.9 Deficiency of nutrient element, unspecified
0.009 0.991 0.000
E61.8 Deficiency of other specified nutrient elements
0.009 0.991 0.000
E61.7 Deficiency of multiple nutrient elements
0.009 0.991 0.000
E61.6 Vanadium deficiency
0.009 0.991 0.000
E61.5 Molybdenum deficiency
0.009 0.991 0.000
E61.4 Chromium deficiency
0.009 0.991 0.000
E61.3 Manganese deficiency
0.009 0.991 0.000
E61.0 Copper deficiency
0.009 0.991 0.000
E07.9 Disorder of thyroid, unspecified
0.009 0.991 0.000
M54.56 Low back pain (Lumbar region)
0.009 0.991 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.009 0.991 0.000
E00 Congenital iodine-deficiency syndrome
0.009 0.991 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.009 0.991 0.000
G47.8 Other sleep disorders
0.009 0.991 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.009 0.991 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.009 0.991 0.000
E04 Other non-toxic goitre
0.009 0.991 0.000
G47.4 Narcolepsy and cataplexy
0.009 0.991 0.000
E06.5 Other chronic thyroiditis
0.009 0.991 0.000
E06.4 Drug-induced thyroiditis
0.009 0.991 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.009 0.991 0.000
E06.1 Subacute thyroiditis
0.009 0.991 0.000
E06.0 Acute thyroiditis
0.009 0.991 0.000
I51.7 Cardiomegaly
0.009 0.991 0.000
E24 Cushing's syndrome
0.008 0.991 0.000
E29 Testicular dysfunction
0.008 0.991 0.000
M54.57 Low back pain (Lumbosacral region)
0.009 0.991 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.008 0.991 0.000
M54.5 Low back pain
0.009 0.991 0.000
E34.8 Other specified endocrine disorders
0.008 0.992 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.008 0.992 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.008 0.992 0.000
E07.8 Other specified disorders of thyroid
0.008 0.992 0.000
G47.2 Disorders of the sleep-wake schedule
0.008 0.992 0.000
E26.9 Hyperaldosteronism, unspecified
0.008 0.992 0.000
E26.8 Other hyperaldosteronism
0.008 0.992 0.000
E26.1 Secondary hyperaldosteronism
0.008 0.992 0.000
E34.5 Androgen resistance syndrome
0.008 0.992 0.000
E34.4 Constitutional tall stature
0.008 0.992 0.000
E34.3 Short stature, not elsewhere classified
0.008 0.992 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.008 0.992 0.000
E34.1 Other hypersecretion of intestinal hormones
0.008 0.992 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.008 0.992 0.000
E45 Retarded development following protein-energy malnutrition
0.008 0.992 0.000
E43 Unspecified severe protein-energy malnutrition
0.008 0.992 0.000
E42 Marasmic kwashiorkor
0.008 0.992 0.000
E41 Nutritional marasmus
0.008 0.992 0.000
E40 Kwashiorkor
0.008 0.992 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.008 0.992 0.000
E28 Ovarian dysfunction
0.008 0.992 0.000
E34.0 Carcinoid syndrome
0.008 0.992 0.000
E53.8 Deficiency of other specified B group vitamins
0.008 0.992 0.000
E67 Other hyperalimentation
0.008 0.992 0.000
E68 Sequelae of hyperalimentation
0.008 0.992 0.000
E50.9 Vitamin A deficiency, unspecified
0.008 0.992 0.000
E50.8 Other manifestations of vitamin A deficiency
0.008 0.992 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.008 0.992 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.008 0.992 0.000
E50.5 Vitamin A deficiency with night blindness
0.008 0.992 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.008 0.992 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.008 0.992 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.008 0.992 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.008 0.992 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.008 0.992 0.000
E51.9 Thiamine deficiency, unspecified
0.008 0.992 0.000
E51.8 Other manifestations of thiamine deficiency
0.008 0.992 0.000
E51.2 Wernicke's encephalopathy
0.008 0.992 0.000
E51.1 Beriberi
0.008 0.992 0.000
E56.9 Vitamin deficiency, unspecified
0.008 0.992 0.000
E56.8 Deficiency of other vitamins
0.008 0.992 0.000
E56.1 Deficiency of vitamin K
0.008 0.992 0.000
E56.0 Deficiency of vitamin E
0.008 0.992 0.000
E63.9 Nutritional deficiency, unspecified
0.008 0.992 0.000
E63.8 Other specified nutritional deficiencies
0.008 0.992 0.000
E63.1 Imbalance of constituents of food intake
0.008 0.992 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.008 0.992 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.008 0.992 0.000
E64.8 Sequelae of other nutritional deficiencies
0.008 0.992 0.000
E64.3 Sequelae of rickets
0.008 0.992 0.000
E64.2 Sequelae of vitamin C deficiency
0.008 0.992 0.000
E64.1 Sequelae of vitamin A deficiency
0.008 0.992 0.000
E64.0 Sequelae of protein-energy malnutrition
0.008 0.992 0.000
E46 Unspecified protein-energy malnutrition
0.008 0.992 0.000
E07.1 Dyshormogenetic goitre
0.008 0.992 0.000
E07.0 Hypersecretion of calcitonin
0.008 0.992 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.008 0.992 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.008 0.992 0.000
E21.4 Other specified disorders of parathyroid gland
0.008 0.992 0.000
E53.1 Pyridoxine deficiency
0.008 0.992 0.000
E53.0 Riboflavin deficiency
0.008 0.992 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.008 0.992 0.000
E06.9 Thyroiditis, unspecified
0.007 0.992 0.000
E23 Hypofunction and other disorders of pituitary gland
0.007 0.992 0.000
E15 Nondiabetic hypoglycaemic coma
0.007 0.993 0.000
E25.9 Adrenogenital disorder, unspecified
0.007 0.993 0.000
E25.8 Other adrenogenital disorders
0.007 0.993 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.007 0.993 0.000
E30.9 Disorder of puberty, unspecified
0.007 0.993 0.000
E30.8 Other disorders of puberty
0.007 0.993 0.000
E30.1 Precocious puberty
0.007 0.993 0.000
E30.0 Delayed puberty
0.007 0.993 0.000
E31.9 Polyglandular dysfunction, unspecified
0.007 0.993 0.000
E31.8 Other polyglandular dysfunction
0.007 0.993 0.000
E31.1 Polyglandular hyperfunction
0.007 0.993 0.000
E31.0 Autoimmune polyglandular failure
0.007 0.993 0.000
E32.9 Disease of thymus, unspecified
0.007 0.993 0.000
E32.8 Other diseases of thymus
0.007 0.993 0.000
E32.1 Abscess of thymus
0.007 0.993 0.000
E32.0 Persistent hyperplasia of thymus
0.007 0.993 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.007 0.993 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.007 0.993 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.007 0.993 0.000
E20.8 Other hypoparathyroidism
0.007 0.993 0.000
E20.1 Pseudohypoparathyroidism
0.007 0.993 0.000
E20.0 Idiopathic hypoparathyroidism
0.007 0.993 0.000
E20.9 Hypoparathyroidism, unspecified
0.007 0.993 0.000
E53.9 Vitamin B deficiency, unspecified
0.007 0.993 0.000
M89.9 Disorder of bone, unspecified
0.007 0.993 0.000
M84.03 Malunion of fracture (Forearm)
0.007 0.993 0.000
M84.0 Malunion of fracture
0.007 0.993 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.007 0.993 0.000
M54 Dorsalgia
0.007 0.993 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.006 0.993 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.006 0.993 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.006 0.993 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.006 0.993 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.006 0.993 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.006 0.993 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.006 0.993 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.006 0.993 0.000
E04.8 Other specified non-toxic goitre
0.006 0.993 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.006 0.993 0.000
E04.0 Non-toxic diffuse goitre
0.006 0.993 0.000
E24.8 Other Cushing's syndrome
0.006 0.994 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.006 0.994 0.000
E24.3 Ectopic ACTH syndrome
0.006 0.994 0.000
E24.2 Drug-induced Cushing's syndrome
0.006 0.994 0.000
E24.1 Nelson's syndrome
0.006 0.994 0.000
E24.0 Pituitary-dependent Cushing's disease
0.006 0.994 0.000
E29.9 Testicular dysfunction, unspecified
0.006 0.994 0.000
E29.8 Other testicular dysfunction
0.006 0.994 0.000
E29.0 Testicular hyperfunction
0.006 0.994 0.000
I50.1 Left ventricular failure
0.006 0.994 0.000
M54.54 Low back pain-Thoracic
0.006 0.994 0.000
M54.53 Low back pain-Cervicothoracic
0.006 0.994 0.000
M54.52 Low back pain-Cervical
0.006 0.994 0.000
M54.51 Low back pain-Occipit-atl-axl
0.006 0.994 0.000
M54.50 Low back pain (Multiple sites in spine)
0.006 0.994 0.000
M54.55 Low back pain (Thoracolumbar region)
0.006 0.994 0.000
I12.9 Hypertensive renal disease without renal failure
0.006 0.994 0.000
E44.1 Mild protein-energy malnutrition
0.006 0.994 0.000
E44.0 Moderate protein-energy malnutrition
0.006 0.994 0.000
E28.9 Ovarian dysfunction, unspecified
0.006 0.994 0.000
E28.8 Other ovarian dysfunction
0.006 0.994 0.000
E28.1 Androgen excess
0.006 0.994 0.000
E28.0 Oestrogen excess
0.006 0.994 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.006 0.994 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.006 0.994 0.000
E67.8 Other specified hyperalimentation
0.006 0.994 0.000
E67.3 Hypervitaminosis D
0.006 0.994 0.000
E67.2 Megavitamin-B6 syndrome
0.006 0.994 0.000
E67.1 Hypercarotenaemia
0.006 0.994 0.000
E67.0 Hypervitaminosis A
0.006 0.994 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M54.4 Lumbago with sciatica
0.006 0.994 0.000
I34.0 Mitral (valve) insufficiency
0.006 0.994 0.000
M84.01 Malunion of fracture (Shoulder region)
0.006 0.994 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.006 0.994 0.000
M84 Disorders of continuity of bone
0.006 0.994 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.006 0.994 0.000
E16 Other disorders of pancreatic internal secretion
0.006 0.994 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.006 0.994 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.005 0.994 0.000
E23.1 Drug-induced hypopituitarism
0.005 0.994 0.000
M54.59 Low back pain (Site unspecified)
0.006 0.994 0.000
Z04.8 Examination and observation for other specified reasons
0.000 0.994 0.006
E03 Other hypothyroidism
0.005 0.994 0.000
E28.3 Primary ovarian failure
0.005 0.994 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.005 0.994 0.000
E23.7 Disorder of pituitary gland, unspecified
0.005 0.995 0.000
E24.9 Cushing's syndrome, unspecified
0.005 0.995 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.005 0.995 0.000
E23.0 Hypopituitarism
0.005 0.995 0.000
G47.3 Sleep apnoea
0.005 0.995 0.000
E29.1 Testicular hypofunction
0.005 0.995 0.000
M84.04 Malunion of fracture (Hand)
0.005 0.995 0.000
E28.2 Polycystic ovarian syndrome
0.005 0.995 0.000
M89.99 Disorder of bone, unspecified (Site unspecified)
0.005 0.995 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.005 0.995 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.005 0.995 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.005 0.995 0.000
M89.90 Disorder of bone, unspecified (Multiple sites)
0.005 0.995 0.000
E23.6 Other disorders of pituitary gland
0.005 0.995 0.000
I11 Hypertensive heart disease
0.005 0.995 0.000
M89 Other disorders of bone
0.005 0.995 0.000
M84.09 Malunion of fracture (Site unspecified)
0.005 0.995 0.000
M84.08 Malunion of fracture (Other)
0.005 0.995 0.000
M84.05 Malunion of fracture (Pelvic region and thigh)
0.005 0.995 0.000
M84.02 Malunion of fracture (Upper arm)
0.005 0.995 0.000
M84.00 Malunion of fracture (Multiple sites)
0.005 0.995 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.005 0.995 0.000
I50.0 Congestive heart failure
0.005 0.995 0.000
M54.8 Other dorsalgia
0.005 0.995 0.000
M54.0 Panniculitis affecting regions of neck and back
0.005 0.995 0.000
M84.06 Malunion of fracture (Lower leg)
0.005 0.995 0.000
M89.98 Disorder of bone, unspecified (Other)
0.005 0.995 0.000
M84.4 Pathological fracture, not elsewhere classified
0.005 0.995 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.005 0.995 0.000
K07.6 Temporomandibular joint disorders
0.005 0.995 0.000
I15 Secondary hypertension
0.005 0.995 0.000
E66 Obesity
0.005 0.995 0.000
M89.8 Other specified disorders of bone
0.005 0.995 0.000
I10-I15 Hypertensive diseases
0.005 0.995 0.000
I12 Hypertensive renal disease
0.005 0.995 0.000
E23.2 Diabetes insipidus
0.004 0.995 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.005 0.995 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.005 0.995 0.000
E16.1 Other hypoglycaemia
0.005 0.995 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.004 0.995 0.000
I15.9 Seconday hypertension, unspecified
0.004 0.995 0.000
N60.3 Fibrosclerosis of breast
0.005 0.995 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.004 0.995 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.004 0.995 0.000
M54.44 Lumbago with sciatica-Thoracic
0.004 0.995 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.004 0.995 0.000
M54.42 Lumbago with sciatica-Cervical
0.004 0.995 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.004 0.995 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.004 0.995 0.000
E21.3 Hyperparathyroidism, unspecified
0.004 0.995 0.000
M54.6 Pain in thoracic spine
0.004 0.995 0.000
I15.1 Hypertension secondary to other renal disorders
0.004 0.995 0.000
E03.8 Other specified hypothyroidism
0.004 0.996 0.000
M84.48 Pathological fracture, not elsewhere classified (Other)
0.004 0.996 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.004 0.996 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.004 0.996 0.000
M84.9 Disorder of continuity of bone, unspecified
0.004 0.996 0.000
M84.8 Other disorders of continuity of bone
0.004 0.996 0.000
M84.3 Stress fracture, not elsewhere classified
0.004 0.996 0.000
M84.2 Delayed union of fracture
0.004 0.996 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.004 0.996 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.004 0.996 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.004 0.996 0.000
E16.4 Abnormal secretion of gastrin
0.004 0.996 0.000
E16.3 Increased secretion of glucagon
0.004 0.996 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.004 0.996 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.004 0.996 0.000
K92.1 Melaena
0.004 0.996 0.000
M89.5 Osteolysis
0.004 0.996 0.000
E03.5 Myxoedema coma
0.004 0.996 0.000
E03.4 Atrophy of thyroid (acquired)
0.004 0.996 0.000
E03.3 Postinfectious hypothyroidism
0.004 0.996 0.000
E03.1 Congenital hypothyroidism without goitre
0.004 0.996 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.004 0.996 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.004 0.996 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.004 0.996 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.004 0.996 0.000
I67.8 Other specified cerebrovascular diseases
0.000 0.996 0.004
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.004 0.996 0.000
N60.4 Mammary duct ectasia
0.004 0.996 0.000
M89.6 Osteopathy after poliomyelitis
0.004 0.996 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.004 0.996 0.000
M89.2 Other disorders of bone development and growth
0.004 0.996 0.000
M89.1 Epiphyseal arrest
0.004 0.996 0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.004 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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