TreeWAS – Variant ID: rs17440619

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H53.2 Diplopia	0.000	0.611	0.389
N48.6 Balanitis xerotica obliterans	0.000	0.862	0.138
N48 Other disorders of penis	0.000	0.872	0.128
N48.8 Other specified disorders of penis	0.000	0.879	0.121
N48.2 Other inflammatory disorders of penis	0.000	0.880	0.120
N48.1 Balanoposthitis	0.000	0.894	0.106
N48.4 Impotence of organic origin	0.000	0.895	0.105
N48.3 Priapism	0.000	0.910	0.090
N48.9 Disorder of penis, unspecified	0.000	0.915	0.085
N48.5 Ulcer of penis	0.000	0.915	0.085
N48.0 Leukoplakia of penis	0.000	0.941	0.059
H53 Visual disturbances	0.000	0.959	0.041
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.031	0.969	0.000
H53.6 Night blindness	0.000	0.971	0.029
H53.5 Colour vision deficiencies	0.000	0.971	0.029
H53.3 Other disorders of binocular vision	0.000	0.971	0.029
H53.4 Visual field defects	0.000	0.974	0.026
H53.0 Amblyopia ex anopsia	0.000	0.974	0.026
I08.1 Disorders of both mitral and tricuspid valves	0.025	0.975	0.000
R16.1 Splenomegaly, not elsewhere classified	0.000	0.977	0.023
H53.1 Subjective visual disturbances	0.000	0.977	0.023
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.022	0.978	0.000
I08 Multiple valve diseases	0.021	0.979	0.000
H53.9 Visual disturbance, unspecified	0.000	0.981	0.019
H53.8 Other visual disturbances	0.000	0.982	0.018
I08.9 Multiple valve disease, unspecified	0.015	0.985	0.000
I08.8 Other multiple valve diseases	0.015	0.985	0.000
H53-H54 Visual disturbances and blindness	0.000	0.985	0.015
I08.2 Disorders of both aortic and tricuspid valves	0.011	0.989	0.000
Z41 Procedures for purposes other than remedying health state	0.011	0.989	0.000
I05-I09 Chronic rheumatic heart diseases	0.011	0.989	0.000
I08.0 Disorders of both mitral and aortic valves	0.011	0.989	0.000
H54 Blindness and low vision	0.000	0.990	0.010
I05 Rheumatic mitral valve diseases	0.010	0.990	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.991	0.009
I09 Other rheumatic heart diseases	0.008	0.991	0.000
I05.1 Rheumatic mitral insufficiency	0.008	0.992	0.000
H72.0 Central perforation of tympanic membrane	0.008	0.992	0.000
Z41.9 Procedures for purposes other than remedying health state, unspecified	0.008	0.992	0.000
Z41.3 Ear piercing	0.008	0.992	0.000
Z41.2 Routine and ritual circumcision	0.008	0.992	0.000
Z41.0 Hair transplant	0.008	0.992	0.000
H69.9 Eustachian tube disorder, unspecified	0.008	0.992	0.000
I05.0 Mitral stenosis	0.008	0.992	0.000
I06 Rheumatic aortic valve diseases	0.008	0.992	0.000
H72 Perforation of tympanic membrane	0.008	0.992	0.000
I05.9 Mitral valve disease, unspecified	0.007	0.993	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.000	0.993	0.007
H69 Other disorders of Eustachian tube	0.007	0.993	0.000
H54.6 Unqualified visual loss, one eye	0.000	0.993	0.007
H54.3 Unqualified visual loss, both eyes	0.000	0.993	0.007
H54.5 Low vision, one eye	0.000	0.993	0.007
Z41.8 Other procedures for purposes other than remedying health state	0.007	0.993	0.000
H54.1 Blindness, one eye, low vision, other eye	0.000	0.993	0.007
I05.8 Other mitral valve diseases	0.007	0.993	0.000
H72.1 Attic perforation of tympanic membrane	0.007	0.993	0.000
I09.9 Rheumatic heart disease, unspecified	0.007	0.993	0.000
I07 Rheumatic tricuspid valve diseases	0.007	0.993	0.000
H54.7 Unspecified visual loss	0.000	0.993	0.007
H74.0 Tympanosclerosis	0.007	0.993	0.000
I05.2 Mitral stenosis with insufficiency	0.006	0.993	0.000
G62.9 Polyneuropathy, unspecified	0.000	0.994	0.006
H65-H75 Diseases of middle ear and mastoid	0.006	0.994	0.000
I09.8 Other specified rheumatic heart diseases	0.006	0.994	0.000
I09.2 Chronic rheumatic pericarditis	0.006	0.994	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.006	0.994	0.000
I09.0 Rheumatic myocarditis	0.006	0.994	0.000
H54.4 Blindness, one eye	0.000	0.994	0.006
H69.8 Other specified disorders of Eustachian tube	0.006	0.994	0.000
H74 Other disorders of middle ear and mastoid	0.006	0.994	0.000
H54.2 Low vision, both eyes	0.000	0.994	0.006
I06.9 Rheumatic aortic valve disease, unspecified	0.006	0.994	0.000
I06.8 Other rheumatic aortic valve diseases	0.006	0.994	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.006	0.994	0.000
I06.1 Rheumatic aortic insufficiency	0.006	0.994	0.000
H71 Cholesteatoma of middle ear	0.006	0.994	0.000
H72.8 Other perforations of tympanic membrane	0.006	0.994	0.000
H72.2 Other marginal perforations of tympanic membrane	0.006	0.994	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.006	0.994	0.000
I06.0 Rheumatic aortic stenosis	0.005	0.994	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.994	0.006
H69.0 Patulous Eustachian tube	0.005	0.995	0.000
I07.9 Tricuspid valve disease, unspecified	0.005	0.995	0.000
I07.8 Other tricuspid valve diseases	0.005	0.995	0.000
I07.2 Tricuspid stenosis with insufficiency	0.005	0.995	0.000
I07.0 Tricuspid stenosis	0.005	0.995	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.005	0.995	0.000
H68 Eustachian salpingitis and obstruction	0.005	0.995	0.000
H67 Otitis media in diseases classified elsewhere	0.005	0.995	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.005	0.995	0.000
K50.1 Crohn's disease of large intestine	0.000	0.995	0.005
H74.3 Other acquired abnormalities of ear ossicles	0.004	0.996	0.000
H54.0 Blindness, both eyes	0.000	0.996	0.004
H73 Other disorders of tympanic membrane	0.004	0.996	0.000
H70 Mastoiditis and related conditions	0.004	0.996	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.004	0.996	0.000
L85.9 Epidermal thickening, unspecified	0.000	0.996	0.004
H90.5 Sensorineural hearing loss, unspecified	0.004	0.996	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.004	0.996	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.004	0.996	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.996	0.004
H74.1 Adhesive middle ear disease	0.004	0.996	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.004	0.996	0.000
H90.2 Conductive hearing loss, unspecified	0.004	0.996	0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.004	0.996	0.000
G62 Other polyneuropathies	0.000	0.996	0.004
H67.8 Otitis media in other diseases classified elsewhere	0.004	0.996	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.004	0.996	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.004	0.996	0.000
H68.1 Obstruction of Eustachian tube	0.004	0.996	0.000
H68.0 Eustachian salpingitis	0.004	0.996	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.004	0.996	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
I07.1 Tricuspid insufficiency	0.004	0.996	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.004	0.996	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
Z49.0 Preparatory care for dialysis	0.000	0.996	0.004
D89.9 Disorder involving the immune mechanism, unspecified	0.004	0.996	0.000
Z49.2 Other dialysis	0.000	0.997	0.003
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.003	0.997	0.000
H90 Conductive and sensorineural hearing loss	0.003	0.997	0.000
H70.8 Other mastoiditis and related conditions	0.003	0.997	0.000
H70.2 Petrositis	0.003	0.997	0.000
H70.1 Chronic mastoiditis	0.003	0.997	0.000
H70.0 Acute mastoiditis	0.003	0.997	0.000
H73.1 Chronic myringitis	0.003	0.997	0.000
H73.0 Acute myringitis	0.003	0.997	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.003	0.997	0.000
R25.2 Cramp and spasm	0.000	0.997	0.003
H74.4 Polyp of middle ear	0.003	0.997	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.997	0.003
D89.0 Polyclonal hypergammaglobulinaemia	0.003	0.997	0.000
K50.0 Crohn's disease of small intestine	0.000	0.997	0.003
I89.0 Lymphoedema, not elsewhere classified	0.000	0.997	0.003
G62.1 Alcoholic polyneuropathy	0.000	0.997	0.003
T78.4 Allergy, unspecified	0.000	0.997	0.003
G62.2 Polyneuropathy due to other toxic agents	0.000	0.997	0.003
G62.0 Drug-induced polyneuropathy	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
Z49 Care involving dialysis	0.000	0.997	0.003
H65 Nonsuppurative otitis media	0.003	0.997	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
H66 Suppurative and unspecified otitis media	0.003	0.997	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
D89.3 Immune reconstitution syndrome	0.003	0.997	0.000
D89.1 Cryoglobulinaemia	0.003	0.997	0.000
H81.9 Disorder of vestibular function, unspecified	0.000	0.997	0.003
H73.8 Other specified disorders of tympanic membrane	0.003	0.997	0.000
H81 Disorders of vestibular function	0.000	0.997	0.003
H70.9 Mastoiditis, unspecified	0.003	0.997	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.997	0.003
R25 Abnormal involuntary movements	0.000	0.997	0.003
H81.1 Benign paroxysmal vertigo	0.000	0.997	0.003
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
R25.3 Fasciculation	0.000	0.997	0.003
K50.8 Other Crohn's disease	0.000	0.997	0.003
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.003	0.997	0.000
H65.2 Chronic serous otitis media	0.003	0.997	0.000
N90.5 Atrophy of vulva	0.003	0.997	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.997	0.003
G61.8 Other inflammatory polyneuropathies	0.000	0.997	0.003
D84 Other immunodeficiencies	0.003	0.997	0.000
H83.0 Labyrinthitis	0.000	0.997	0.003
M84.1 Nonunion of fracture [pseudarthrosis]	0.003	0.997	0.000
K50.9 Crohn's disease, unspecified	0.000	0.997	0.003
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.997	0.003
Z49.1 Extracorporeal dialysis	0.000	0.997	0.003
H81.2 Vestibular neuronitis	0.000	0.997	0.002
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.002	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
D86.9 Sarcoidosis, unspecified	0.003	0.997	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.997	0.000
D86 Sarcoidosis	0.002	0.997	0.000
H80-H83 Diseases of inner ear	0.000	0.997	0.002
Chapter VIII Diseases of the ear and mastoid process	0.002	0.997	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
H83 Other diseases of inner ear	0.000	0.998	0.002
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.998	0.002
H60 Otitis externa	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
G61 Inflammatory polyneuropathy	0.000	0.998	0.002
H60.3 Other infective otitis externa	0.002	0.998	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.998	0.002
H65.1 Other acute nonsuppurative otitis media	0.002	0.998	0.000
H65.0 Acute serous otitis media	0.002	0.998	0.000
G62.8 Other specified polyneuropathies	0.000	0.998	0.002
H66.1 Chronic tubotympanic suppurative otitis media	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.002	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
H50.1 Divergent concomitant strabismus	0.000	0.998	0.002
H81.0 Meniere's disease	0.000	0.998	0.002
H81.8 Other disorders of vestibular function	0.000	0.998	0.002
H81.4 Vertigo of central origin	0.000	0.998	0.002
H66.0 Acute suppurative otitis media	0.002	0.998	0.000
H81.3 Other peripheral vertigo	0.000	0.998	0.002
H66.4 Suppurative otitis media, unspecified	0.002	0.998	0.000
R25.0 Abnormal head movements	0.000	0.998	0.002
H90-H95 Other disorders of ear	0.002	0.998	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.002	0.998	0.000
Z87.8 Personal history of other specified conditions	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
H60-H62 Diseases of external ear	0.002	0.998	0.000
H60.5 Acute otitis externa, non-infective	0.002	0.998	0.000
I67.2 Cerebral atherosclerosis	0.000	0.998	0.002
R25.1 Tremor, unspecified	0.000	0.998	0.002
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.998	0.002
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.998	0.002
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
H60.8 Other otitis externa	0.002	0.998	0.000
H60.4 Cholesteatoma of external ear	0.002	0.998	0.000
T39.0 Salicylates	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
L27 Dermatitis due to substances taken internally	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.002	0.998	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.000	0.998	0.002
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.998	0.002
H60.2 Malignant otitis externa	0.002	0.998	0.000
H60.0 Abscess of external ear	0.002	0.998	0.000
H83.9 Disease of inner ear, unspecified	0.000	0.998	0.002
H83.8 Other specified diseases of inner ear	0.000	0.998	0.002
H83.3 Noise effects on inner ear	0.000	0.998	0.002
H83.2 Labyrinthine dysfunction	0.000	0.998	0.002
H83.1 Labyrinthine fistula	0.000	0.998	0.002
G61.1 Serum neuropathy	0.000	0.998	0.002
H60.1 Cellulitis of external ear	0.002	0.998	0.000
Z93.3 Colostomy status	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
G64 Other disorders of peripheral nervous system	0.000	0.998	0.002
H80 Otosclerosis	0.000	0.998	0.002
H33.3 Retinal breaks without detachment	0.000	0.998	0.002
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.998	0.002
T50.9 Other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.002	0.998	0.000
G63.2 Diabetic polyneuropathy	0.000	0.998	0.002
H66.9 Otitis media, unspecified	0.002	0.998	0.000
H90.0 Conductive hearing loss, bilateral	0.002	0.998	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.998	0.002
D11.0 Parotid gland	0.000	0.998	0.002
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.002	0.998	0.000
T42.4 Benzodiazepines	0.002	0.998	0.000
M84 Disorders of continuity of bone	0.002	0.998	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.002	0.998	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.002	0.998	0.000
G61.0 Guillain-Barre syndrome	0.000	0.998	0.002
I67.1 Cerebral aneurysm, nonruptured	0.000	0.998	0.002
H62 Disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.998	0.000
L27.2 Dermatitis due to ingested food	0.002	0.998	0.000
D34 Benign neoplasm of thyroid gland	0.002	0.998	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.000	0.998	0.002
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.998	0.002
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.998	0.002
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.998	0.002
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.998	0.002
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.998	0.002
G63.1 Polyneuropathy in neoplastic disease	0.000	0.998	0.002
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.998	0.002
C41.1 Mandible	0.002	0.998	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.002	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.002	0.998	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
K07.3 Anomalies of tooth position	0.000	0.998	0.002
M54.4 Lumbago with sciatica	0.000	0.998	0.002
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
G60 Hereditary and idiopathic neuropathy	0.000	0.998	0.002
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.002	0.998	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.002	0.998	0.000
H95.1 Other disorders following mastoidectomy	0.002	0.998	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.002	0.998	0.000
L27.8 Dermatitis due to other substances taken internally	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.998	0.002
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.998	0.002
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.998	0.002
D83.8 Other common variable immunodeficiencies	0.001	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.998	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.002	0.998	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M84.8 Other disorders of continuity of bone	0.002	0.998	0.000
M84.0 Malunion of fracture	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.002	0.998	0.000
H80.8 Other otosclerosis	0.000	0.998	0.001
H80.2 Cochlear otosclerosis	0.000	0.998	0.001
H80.1 Otosclerosis involving oval window, obliterative	0.000	0.998	0.001
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.998	0.001
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.998	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.001	0.998	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
M84.9 Disorder of continuity of bone, unspecified	0.002	0.998	0.000
M84.2 Delayed union of fracture	0.002	0.998	0.000
T50.8 Diagnostic agents	0.002	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.001	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.001	0.998	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.001	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.001	0.998	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.001	0.998	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
H62.2 Otitis externa in mycoses	0.001	0.998	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.001	0.998	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.001	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
H90.3 Sensorineural hearing loss, bilateral	0.001	0.998	0.000
H65.3 Chronic mucoid otitis media	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
T36.3 Macrolides	0.001	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.001	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.001	0.998	0.000
T50.5 Appetite depressants	0.001	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.001	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.001	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.001	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.001	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.001	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.001	0.998	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.001	0.998	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.001	0.998	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
H80.9 Otosclerosis, unspecified	0.000	0.998	0.001
I67.9 Cerebrovascular disease, unspecified	0.000	0.998	0.002
M54.49 Lumbago with sciatica (Site unspecified)	0.000	0.998	0.001
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.000	0.998	0.001
M54.44 Lumbago with sciatica-Thoracic	0.000	0.998	0.001
M54.43 Lumbago with sciatica-Cervicothoracic	0.000	0.998	0.001
M54.42 Lumbago with sciatica-Cervical	0.000	0.998	0.001
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.000	0.998	0.001
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.000	0.998	0.001
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.001	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.998	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.000	0.998	0.001
G60.3 Idiopathic progressive neuropathy	0.000	0.998	0.001
G60.2 Neuropathy in association with hereditary ataxia	0.000	0.998	0.001
G60.1 Refsum's disease	0.000	0.998	0.001
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.001	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.001	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.001	0.998	0.000
T42.0 Hydantoin derivatives	0.001	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.001	0.998	0.000
R29.4 Clicking hip	0.000	0.998	0.001
R29.3 Abnormal posture	0.000	0.998	0.001
R29.2 Abnormal reflex	0.000	0.998	0.001
R29.0 Tetany	0.000	0.998	0.001
T46.3 Coronary vasodilators, not elsewhere classified	0.001	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.998	0.000
M20.3 Other deformity of hallux (acquired)	0.000	0.998	0.002
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.001	0.998	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.002	0.998	0.000
I67 Other cerebrovascular diseases	0.000	0.998	0.002
M84.09 Malunion of fracture (Site unspecified)	0.001	0.998	0.000
M84.08 Malunion of fracture (Other)	0.001	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.001	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.001	0.998	0.000
C41.9 Bone and articular cartilage, unspecified	0.001	0.998	0.000
M31.6 Other giant cell arteritis	0.002	0.998	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.001	0.998	0.000
M84.88 Other disorders of continuity of bone (Other)	0.001	0.998	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.001	0.998	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.001	0.998	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.001	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.001	0.998	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.001	0.998	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.001	0.998	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.001	0.998	0.000
R29.1 Meningismus	0.000	0.998	0.001
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
T47.7 Emetics	0.001	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.001	0.998	0.000
T47.5 Digestants	0.001	0.998	0.000
T47.4 Other laxatives	0.001	0.998	0.000
T47.3 Saline and osmotic laxatives	0.001	0.998	0.000
T47.2 Stimulant laxatives	0.001	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.001	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.001	0.999	0.000
G60.0 Hereditary motor and sensory neuropathy	0.000	0.999	0.001
R09.2 Respiratory arrest	0.001	0.999	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.999	0.001
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
M84.03 Malunion of fracture (Forearm)	0.001	0.999	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.001	0.999	0.000
M84.28 Delayed union of fracture (Other)	0.001	0.999	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.001	0.999	0.000
M84.26 Delayed union of fracture (Lower leg)	0.001	0.999	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.001	0.999	0.000
M84.24 Delayed union of fracture (Hand)	0.001	0.999	0.000
M84.23 Delayed union of fracture (Forearm)	0.001	0.999	0.000
M84.22 Delayed union of fracture (Upper arm)	0.001	0.999	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.001	0.999	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.001	0.999	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.001	0.999	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.001	0.999	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.001	0.999	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.001	0.999	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.001	0.999	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.001	0.999	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.001	0.999	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.001	0.999	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.001	0.999	0.000
E06.5 Other chronic thyroiditis	0.001	0.999	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.999	0.000
C22.9 Liver, unspecified	0.001	0.999	0.000
D21.3 Connective and other soft tissue of thorax	0.001	0.999	0.000
N80.3 Endometriosis of pelvic peritoneum	0.001	0.999	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.001	0.999	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.999	0.001
W44.0 Home	0.000	0.999	0.001
H91 Other hearing loss	0.001	0.999	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.001	0.999	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.999	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.001	0.999	0.000
M54.12 Radiculopathy (Cervical region)	0.000	0.999	0.001
H91.8 Other specified hearing loss	0.001	0.999	0.000
T36.9 Systemic antibiotic, unspecified	0.001	0.999	0.000
T36.8 Other systemic antibiotics	0.001	0.999	0.000
T36.7 Antifungal antibiotics, systemically used	0.001	0.999	0.000
T36.6 Rifamycins	0.001	0.999	0.000
T36.5 Aminoglycosides	0.001	0.999	0.000
T36.4 Tetracyclines	0.001	0.999	0.000
T36.2 Chloramphenicol group	0.001	0.999	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.001	0.999	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.001	0.999	0.000
T45.8 Other primarily systemic and haematological agents	0.001	0.999	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.001	0.999	0.000
T45.6 Fibrinolysis-affecting drugs	0.001	0.999	0.000
T45.4 Iron and its compounds	0.001	0.999	0.000
T45.3 Enzymes, not elsewhere classified	0.001	0.999	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.001	0.999	0.000
H92 Otalgia and effusion of ear	0.001	0.999	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations