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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17564083
log Bayes Factor = 5.59903
Chromosome 14   position 29,967,193  (GRCh37) Explore rs17564083 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M50-M54 Other dorsopathies
0.999 0.001 0.000
M54 Dorsalgia
0.999 0.001 0.000
M54.5 Low back pain
0.996 0.004 0.000
M20-M25 Other joint disorders
0.994 0.006 0.000
Chapter VI Diseases of the nervous system
0.993 0.007 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.991 0.009 0.000
# Top node
0.991 0.009 0.000
D69 Purpura and other haemorrhagic conditions
0.989 0.011 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.989 0.011 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.989 0.011 0.000
G90-G99 Other disorders of the nervous system
0.989 0.011 0.000
M22 Disorders of patella
0.987 0.013 0.000
D60-D64 Aplastic and other anaemias
0.986 0.014 0.000
D64 Other anaemias
0.984 0.016 0.000
D69.6 Thrombocytopenia, unspecified
0.984 0.016 0.000
D64.9 Anaemia, unspecified
0.984 0.016 0.000
G62 Other polyneuropathies
0.980 0.020 0.000
M54.57 Low back pain (Lumbosacral region)
0.980 0.020 0.000
M15-M19 Arthrosis
0.980 0.020 0.000
G62.9 Polyneuropathy, unspecified
0.974 0.026 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.972 0.028 0.000
Chapter V Mental and behavioural disorders
0.964 0.036 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.962 0.038 0.000
M22.8 Other disorders of patella
0.955 0.045 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.954 0.046 0.000
G95 Other diseases of spinal cord
0.953 0.047 0.000
M18 Arthrosis of first carpometacarpal joint
0.942 0.058 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.942 0.058 0.000
M24 Other specific joint derangements
0.941 0.059 0.000
M19 Other arthrosis
0.940 0.060 0.000
M54.50 Low back pain (Multiple sites in spine)
0.937 0.063 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.927 0.073 0.000
M54.3 Sciatica
0.926 0.074 0.000
G60 Hereditary and idiopathic neuropathy
0.925 0.075 0.000
M22.3 Other derangements of patella
0.911 0.089 0.000
G96 Other disorders of central nervous system
0.908 0.092 0.000
M31 Other necrotising vasculopathies
0.907 0.093 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.903 0.097 0.000
F10.1 Harmful use
0.902 0.098 0.000
M45-M49 Spondylopathies
0.902 0.098 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.901 0.099 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.901 0.099 0.000
M05-M14 Inflammatory polyarthropathies
0.900 0.100 0.000
M34 Systemic sclerosis
0.898 0.102 0.000
M24.1 Other articular cartilage disorders
0.896 0.104 0.000
M13 Other arthritis
0.889 0.111 0.000
M86-M90 Other osteopathies
0.889 0.111 0.000
M60-M63 Disorders of muscles
0.888 0.112 0.000
M19.0 Primary arthrosis of other joints
0.884 0.116 0.000
M48 Other spondylopathies
0.882 0.118 0.000
M13.9 Arthritis, unspecified
0.882 0.118 0.000
Chapter XXII Codes for special purposes
0.879 0.121 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.877 0.123 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.875 0.125 0.000
G95.9 Disease of spinal cord, unspecified
0.871 0.129 0.000
M48.0 Spinal stenosis
0.870 0.130 0.000
M22.2 Patellofemoral disorders
0.869 0.131 0.000
G60.0 Hereditary motor and sensory neuropathy
0.869 0.131 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.868 0.132 0.000
F10.3 Withdrawal state
0.863 0.137 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.863 0.137 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.862 0.138 0.000
M13.94 Arthritis, unspecified (Hand)
0.860 0.140 0.000
M54.39 Sciatica (Site unspecified)
0.858 0.142 0.000
G95.2 Cord compression, unspecified
0.854 0.146 0.000
M00-M03 Infectious arthropathies
0.852 0.148 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.850 0.150 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.850 0.150 0.000
M15 Polyarthrosis
0.849 0.151 0.000
G70-G73 Diseases of myoneural junction and muscle
0.848 0.152 0.000
M51 Other intervertebral disk disorders
0.844 0.156 0.000
G97.8 Other postprocedural disorders of nervous system
0.842 0.158 0.000
F10.2 Dependence syndrome
0.831 0.169 0.000
G20-G26 Extrapyramidal and movement disorders
0.826 0.174 0.000
M54.4 Lumbago with sciatica
0.825 0.175 0.000
G62.1 Alcoholic polyneuropathy
0.819 0.181 0.000
M62 Other disorders of muscle
0.816 0.184 0.000
M48.09 Spinal stenosis (Site unspecified)
0.815 0.185 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.813 0.187 0.000
M22.0 Recurrent dislocation of patella
0.813 0.187 0.000
M54.2 Cervicalgia
0.809 0.191 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.809 0.191 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.809 0.191 0.000
M34.1 CR(E)ST syndrome
0.808 0.192 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.807 0.193 0.000
M54.54 Low back pain-Thoracic
0.807 0.193 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.802 0.198 0.000
M19.9 Arthrosis, unspecified
0.800 0.200 0.000
M91-M94 Chondropathies
0.799 0.201 0.000
M65-M68 Disorders of synovium and tendon
0.796 0.204 0.000
D69.0 Allergic purpura
0.796 0.204 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.796 0.204 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.796 0.204 0.000
G50 Disorders of trigeminal nerve
0.795 0.205 0.000
M54.36 Sciatica (Lumbar region)
0.790 0.210 0.000
F10.6 Amnesic syndrome
0.789 0.211 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.788 0.212 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.788 0.212 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.788 0.212 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.788 0.212 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.785 0.215 0.000
G96.0 Cerebrospinal fluid leak
0.784 0.216 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.783 0.217 0.000
M32 Systemic lupus erythematosus
0.782 0.218 0.000
M13.98 Arthritis, unspecified (Other)
0.781 0.219 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.780 0.220 0.000
G51 Facial nerve disorders
0.778 0.222 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.773 0.227 0.000
M40-M43 Deforming dorsopathies
0.772 0.228 0.000
Q76 Congenital malformations of spine and bony thorax
0.771 0.229 0.000
M54.55 Low back pain (Thoracolumbar region)
0.771 0.229 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.767 0.233 0.000
M31.3 Wegener's granulomatosis
0.766 0.234 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.766 0.234 0.000
M54.1 Radiculopathy
0.765 0.235 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.765 0.235 0.000
G52 Disorders of other cranial nerves
0.764 0.236 0.000
M66 Spontaneous rupture of synovium and tendon
0.762 0.238 0.000
M62.8 Other specified disorders of muscle
0.762 0.238 0.000
G70 Myasthenia gravis and other myoneural disorders
0.761 0.239 0.000
M31.6 Other giant cell arteritis
0.761 0.239 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.759 0.241 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.758 0.242 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.758 0.242 0.000
M87 Osteonecrosis
0.754 0.246 0.000
Q00-Q07 Congenital malformations of the nervous system
0.752 0.247 0.000
M86 Osteomyelitis
0.749 0.251 0.000
Q80-Q89 Other congenital malformations
0.747 0.253 0.000
G95.8 Other specified diseases of spinal cord
0.746 0.254 0.000
U80 Agent resistant to penicillin and related antibiotics
0.746 0.254 0.000
G25 Other extrapyramidal and movement disorders
0.744 0.256 0.000
M15.1 Heberden's nodes (with arthropathy)
0.742 0.258 0.000
M54.30 Sciatica (Multiple sites in spine)
0.742 0.258 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.741 0.259 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.740 0.260 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.738 0.262 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.736 0.264 0.000
F42 Obsessive-compulsive disorder
0.735 0.265 0.000
M00 Pyogenic arthritis
0.734 0.266 0.000
M54.6 Pain in thoracic spine
0.733 0.267 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.728 0.272 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.727 0.273 0.000
G95.0 Syringomyelia and syringobulbia
0.727 0.273 0.000
M22.9 Disorder of patella, unspecified
0.726 0.274 0.000
M24.6 Ankylosis of joint
0.726 0.274 0.000
M31.7 Microscopic polyangiitis
0.726 0.274 0.000
F60-F69 Disorders of adult personality and behaviour
0.725 0.275 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.724 0.276 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.723 0.277 0.000
G62.0 Drug-induced polyneuropathy
0.723 0.277 0.000
Q65 Congenital deformities of hip
0.721 0.279 0.000
Q21 Congenital malformations of cardiac septa
0.720 0.280 0.000
U80.1 Methicillin resistant agent
0.718 0.282 0.000
M66.0 Rupture of popliteal cyst
0.718 0.282 0.000
M54.8 Other dorsalgia
0.716 0.284 0.000
M54.0 Panniculitis affecting regions of neck and back
0.716 0.284 0.000
D69.4 Other primary thrombocytopenia
0.715 0.285 0.000
M54.53 Low back pain-Cervicothoracic
0.714 0.286 0.000
M54.52 Low back pain-Cervical
0.714 0.286 0.000
M54.51 Low back pain-Occipit-atl-axl
0.714 0.286 0.000
G24 Dystonia
0.714 0.286 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.287 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.711 0.289 0.000
G60.8 Other hereditary and idiopathic neuropathies
0.710 0.290 0.000
D69.9 Haemorrhagic condition, unspecified
0.709 0.291 0.000
D69.8 Other specified haemorrhagic conditions
0.709 0.291 0.000
D69.2 Other nonthrombocytopenic purpura
0.709 0.291 0.000
D69.1 Qualitative platelet defects
0.709 0.291 0.000
D67 Hereditary factor IX deficiency
0.709 0.291 0.000
G64 Other disorders of peripheral nervous system
0.709 0.291 0.000
G92 Toxic encephalopathy
0.709 0.291 0.000
M54.59 Low back pain (Site unspecified)
0.709 0.291 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.708 0.292 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.708 0.292 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.708 0.292 0.000
M22.1 Recurrent subluxation of patella
0.708 0.292 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.707 0.293 0.000
F70-F79 Mental retardation
0.706 0.294 0.000
D64.4 Congenital dyserythropoietic anaemia
0.705 0.294 0.000
D64.3 Other sideroblastic anaemias
0.705 0.294 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.705 0.294 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.705 0.294 0.000
D64.0 Hereditary sideroblastic anaemia
0.705 0.294 0.000
Q28 Other congenital malformations of circulatory system
0.705 0.295 0.000
G62.2 Polyneuropathy due to other toxic agents
0.702 0.297 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.701 0.299 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.701 0.299 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.700 0.300 0.000
M94 Other disorders of cartilage
0.700 0.300 0.000
G70.0 Myasthenia gravis
0.699 0.301 0.000
Q35-Q37 Cleft lip and cleft palate
0.697 0.303 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.697 0.303 0.000
M49 Spondylopathies in diseases classified elsewhere
0.697 0.303 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.696 0.304 0.000
M21 Other acquired deformities of limbs
0.695 0.305 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.693 0.307 0.000
D62 Acute posthaemorrhagic anaemia
0.692 0.308 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.691 0.308 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.686 0.313 0.000
M66.06 Rupture of popliteal cyst-Lower leg
0.686 0.314 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.686 0.314 0.000
M48.04 Spinal stenosis (Thoracic region)
0.685 0.315 0.000
M53 Other dorsopathies, not elsewhere classified
0.685 0.315 0.000
M19.2 Other secondary arthrosis
0.685 0.315 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.684 0.316 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.684 0.316 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.684 0.316 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.684 0.316 0.000
G50.0 Trigeminal neuralgia
0.684 0.316 0.000
F03 Unspecified dementia
0.683 0.317 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.682 0.317 0.000
G91 Hydrocephalus
0.680 0.320 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.679 0.321 0.000
M89 Other disorders of bone
0.676 0.324 0.000
M30 Polyarteritis nodosa and related conditions
0.676 0.324 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.676 0.324 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.676 0.324 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.676 0.324 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.676 0.324 0.000
F10.8 Other mental and behavioural disorders
0.675 0.325 0.000
F10.7 Residual and late-onset psychotic disorder
0.675 0.325 0.000
M34.8 Other forms of systemic sclerosis
0.675 0.325 0.000
M24.9 Joint derangement, unspecified
0.675 0.325 0.000
M24.7 Protrusio acetabuli
0.675 0.325 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.675 0.325 0.000
M34.9 Systemic sclerosis, unspecified
0.675 0.325 0.000
M19.8 Other specified arthrosis
0.674 0.326 0.000
D61 Other aplastic anaemias
0.673 0.326 0.000
M15.4 Erosive (osteo)arthrosis
0.672 0.328 0.000
M86.6 Other chronic osteomyelitis
0.671 0.329 0.000
M19.1 Posttraumatic arthrosis of other joints
0.671 0.329 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.670 0.330 0.000
M13.0 Polyarthritis, unspecified
0.670 0.330 0.000
Q27 Other congenital malformations of peripheral vascular system
0.670 0.330 0.000
M11 Other crystal arthropathies
0.670 0.330 0.000
G51.0 Bell's palsy
0.668 0.332 0.000
D55-D59 Haemolytic anaemias
0.668 0.332 0.000
M48.02 Spinal stenosis (Cervical region)
0.668 0.332 0.000
F10.9 Unspecified mental and behavioural disorder
0.667 0.333 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.666 0.334 0.000
Q24 Other congenital malformations of heart
0.666 0.334 0.000
Chapter I Certain infectious and parasitic diseases
0.665 0.335 0.000
M54.35 Sciatica (Thoracolumbar region)
0.664 0.336 0.000
M54.34 Sciatica-Thoracic
0.664 0.336 0.000
M54.33 Sciatica-Cervicothoracic
0.664 0.336 0.000
M54.32 Sciatica-Cervical
0.664 0.336 0.000
M54.31 Sciatica-Occipit-atl-axl
0.664 0.336 0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.663 0.337 0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.663 0.337 0.000
G60.3 Idiopathic progressive neuropathy
0.663 0.337 0.000
G60.2 Neuropathy in association with hereditary ataxia
0.663 0.337 0.000
G60.1 Refsum's disease
0.663 0.337 0.000
M15.8 Other polyarthrosis
0.662 0.338 0.000
Q39 Congenital malformations of oesophagus
0.662 0.338 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.662 0.338 0.000
F19.1 Harmful use
0.661 0.339 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.660 0.340 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.660 0.340 0.000
F45 Somatoform disorders
0.660 0.340 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.658 0.342 0.000
Q66 Congenital deformities of feet
0.657 0.343 0.000
Q96 Turner's syndrome
0.656 0.344 0.000
G61 Inflammatory polyneuropathy
0.655 0.345 0.000
M12 Other specific arthropathies
0.653 0.347 0.000
M24.5 Contracture of joint
0.653 0.347 0.000
G96.9 Disorder of central nervous system, unspecified
0.651 0.349 0.000
G96.8 Other specified disorders of central nervous system
0.651 0.349 0.000
F42.9 Obsessive-compulsive disorder, unspecified
0.651 0.349 0.000
M31.9 Necrotising vasculopathy, unspecified
0.650 0.350 0.000
M31.8 Other specified necrotising vasculopathies
0.650 0.350 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.650 0.350 0.000
M31.2 Lethal midline granuloma
0.650 0.350 0.000
M31.1 Thrombotic microangiopathy
0.650 0.350 0.000
M31.0 Hypersensitivity angiitis
0.650 0.350 0.000
M00.9 Pyogenic arthritis, unspecified
0.650 0.350 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.648 0.352 0.000
G52.9 Cranial nerve disorder, unspecified
0.647 0.353 0.000
Q78 Other osteochondrodysplasias
0.646 0.354 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.646 0.354 0.000
Q75 Other congenital malformations of skull and face bones
0.646 0.354 0.000
Q74 Other congenital malformations of limb(s)
0.646 0.354 0.000
Q73 Reduction defects of unspecified limb
0.646 0.354 0.000
Q72 Reduction defects of lower limb
0.646 0.354 0.000
Q71 Reduction defects of upper limb
0.646 0.354 0.000
Q70 Syndactyly
0.646 0.354 0.000
Q69 Polydactyly
0.646 0.354 0.000
Q68 Other congenital musculoskeletal deformities
0.646 0.354 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.646 0.354 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.646 0.354 0.000
M13.8 Other specified arthritis
0.646 0.354 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.645 0.354 0.000
M08 Juvenile arthritis
0.645 0.354 0.000
M19.06 Primary arthrosis of other joints-Lower leg
0.645 0.355 0.000
Q76.1 Klippel-Feil syndrome
0.644 0.356 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.644 0.356 0.000
M34.0 Progressive systemic sclerosis
0.644 0.356 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.642 0.358 0.000
M24.18 Other articular cartilage disorders (Other)
0.642 0.358 0.000
M24.14 Other articular cartilage disorders (Hand)
0.642 0.358 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.642 0.358 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.642 0.358 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.641 0.359 0.000
G58 Other mononeuropathies
0.638 0.362 0.000
M05 Seropositive rheumatoid arthritis
0.638 0.362 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.637 0.363 0.000
M61 Calcification and ossification of muscle
0.637 0.363 0.000
M19.00 Primary arthrosis of other joints (Multiple sites)
0.637 0.363 0.000
M41 Scoliosis
0.635 0.365 0.000
Q17 Other congenital malformations of ear
0.635 0.365 0.000
G51.9 Disorder of facial nerve, unspecified
0.635 0.365 0.000
G90 Disorders of autonomic nervous system
0.634 0.365 0.000
D66 Hereditary factor VIII deficiency
0.634 0.366 0.000
M19.08 Primary arthrosis of other joints (Other)
0.634 0.366 0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)
0.634 0.366 0.000
M02 Reactive arthropathies
0.634 0.366 0.000
F44 Dissociative [conversion] disorders
0.633 0.367 0.000
M48.9 Spondylopathy, unspecified
0.633 0.367 0.000
M48.8 Other specified spondylopathies
0.633 0.367 0.000
M48.4 Fatigue fracture of vertebra
0.633 0.367 0.000
M48.3 Traumatic spondylopathy
0.633 0.367 0.000
M48.2 Kissing spine
0.633 0.367 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.633 0.367 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.632 0.368 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.631 0.369 0.000
Q21.0 Ventricular septal defect
0.630 0.370 0.000
G30-G32 Other degenerative diseases of the nervous system
0.630 0.370 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.629 0.371 0.000
D64.8 Other specified anaemias
0.629 0.371 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.627 0.373 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.627 0.373 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.627 0.373 0.000
M90 Osteopathies in diseases classified elsewhere
0.626 0.374 0.000
F40 Phobic anxiety disorders
0.626 0.374 0.000
F43 Reaction to severe stress, and adjustment disorders
0.626 0.374 0.000
G57 Mononeuropathies of lower limb
0.626 0.374 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.625 0.375 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.625 0.375 0.000
F11 Mental and behavioural disorders due to use of opioids
0.624 0.375 0.000
M87.2 Osteonecrosis due to previous trauma
0.624 0.376 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.624 0.376 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.624 0.376 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.624 0.376 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.624 0.376 0.000
F10.5 Psychotic disorder
0.622 0.378 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.622 0.378 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.622 0.378 0.000
F41 Other anxiety disorders
0.620 0.380 0.000
M94.9 Disorder of cartilage, unspecified
0.620 0.380 0.000
M51.9 Intervertebral disk disorder, unspecified
0.620 0.380 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.619 0.381 0.000
D69.5 Secondary thrombocytopenia
0.619 0.381 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.619 0.381 0.000
Q26 Congenital malformations of great veins
0.618 0.381 0.000
Q25 Congenital malformations of great arteries
0.618 0.381 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.618 0.381 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.618 0.381 0.000
G24.9 Dystonia, unspecified
0.617 0.383 0.000
M46 Other inflammatory spondylopathies
0.616 0.384 0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.615 0.385 0.000
M66.2 Spontaneous rupture of extensor tendons
0.615 0.385 0.000
M54.22 Cervicalgia (Cervical region)
0.615 0.385 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.613 0.387 0.000
M54.56 Low back pain (Lumbar region)
0.613 0.387 0.000
M13.1 Monoarthritis, not elsewhere classified
0.612 0.388 0.000
Q07 Other congenital malformations of nervous system
0.611 0.389 0.000
M51.2 Other specified intervertebral disk displacement
0.611 0.389 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.611 0.389 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.611 0.389 0.000
F99-F99 Unspecified mental disorder
0.610 0.390 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.609 0.390 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.609 0.390 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.609 0.390 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.609 0.390 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.609 0.390 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.609 0.390 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.609 0.391 0.000
M60 Myositis
0.608 0.391 0.000
M15.9 Polyarthrosis, unspecified
0.608 0.391 0.000
M15.0 Primary generalised (osteo)arthrosis
0.608 0.391 0.000
M15.3 Secondary multiple arthrosis
0.608 0.391 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.608 0.392 0.000
G59.0 Diabetic mononeuropathy
0.606 0.394 0.000
F19.2 Dependence syndrome
0.606 0.394 0.000
M54.14 Radiculopathy (Thoracic region)
0.606 0.394 0.000
M51.3 Other specified intervertebral disk degeneration
0.605 0.394 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.605 0.394 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.604 0.396 0.000
M40 Kyphosis and lordosis
0.604 0.396 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.603 0.397 0.000
M54.29 Cervicalgia-Site unspe
0.603 0.397 0.000
M62.88 Other specified disorders of muscle (Other)
0.603 0.397 0.000
M35 Other systemic involvement of connective tissue
0.603 0.397 0.000
G50.1 Atypical facial pain
0.602 0.398 0.000
G03 Meningitis due to other and unspecified causes
0.598 0.402 0.000
M87.9 Osteonecrosis, unspecified
0.598 0.402 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.597 0.403 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.597 0.403 0.000
F12.2 Dependence syndrome
0.595 0.405 0.000
G95.1 Vascular myelopathies
0.593 0.407 0.000
G25.2 Other specified forms of tremor
0.592 0.407 0.000
G23 Other degenerative diseases of basal ganglia
0.592 0.408 0.000
G21 Secondary Parkinsonism
0.592 0.408 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.592 0.408 0.000
G22 Parkinsonism in diseases classified elsewhere
0.592 0.408 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.591 0.408 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.591 0.408 0.000
M54.44 Lumbago with sciatica-Thoracic
0.591 0.408 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.591 0.408 0.000
M54.42 Lumbago with sciatica-Cervical
0.591 0.408 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.591 0.408 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.591 0.408 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.591 0.409 0.000
Q65.8 Other congenital deformities of hip
0.591 0.409 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.590 0.409 0.000
M25 Other joint disorders, not elsewhere classified
0.590 0.410 0.000
Q50-Q56 Congenital malformations of genital organs
0.588 0.412 0.000
F00 Dementia in Alzheimer's disease
0.588 0.412 0.000
G51.8 Other disorders of facial nerve
0.587 0.413 0.000
M54.9 Dorsalgia, unspecified
0.587 0.413 0.000
M88 Paget's disease of bone [osteitis deformans]
0.587 0.413 0.000
M66.4 Spontaneous rupture of other tendons
0.586 0.414 0.000
G72 Other myopathies
0.586 0.414 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.585 0.415 0.000
Q12 Congenital lens malformations
0.585 0.415 0.000
Q44.6 Cystic disease of liver
0.585 0.415 0.000
M62.9 Disorder of muscle, unspecified
0.585 0.415 0.000
M62.6 Muscle strain
0.585 0.415 0.000
M62.4 Contracture of muscle
0.585 0.415 0.000
M62.3 Immobility syndrome (paraplegic)
0.585 0.415 0.000
M62.2 Ischaemic infarction of muscle
0.585 0.415 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.585 0.415 0.000
M62.0 Diastasis of muscle
0.585 0.415 0.000
M19.02 Primary arthrosis of other joints (Upper arm)
0.584 0.416 0.000
G00 Bacterial meningitis, not elsewhere classified
0.584 0.416 0.000
G71 Primary disorders of muscles
0.584 0.416 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.583 0.417 0.000
M21.7 Unequal limb length (acquired)
0.583 0.417 0.000
M99 Biomechanical lesions, not elsewhere classified
0.583 0.417 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.582 0.418 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.580 0.420 0.000
M54.27 Cervicalgia-Lumbosacral
0.580 0.420 0.000
M54.26 Cervicalgia-Lumbar
0.580 0.420 0.000
M54.25 Cervicalgia-Thoracolumbar
0.580 0.420 0.000
M54.24 Cervicalgia-Thoracic
0.580 0.420 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.580 0.420 0.000
M54.20 Cervicalgia-Mult site
0.580 0.420 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.580 0.420 0.000
Q45 Other congenital malformations of digestive system
0.580 0.420 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.580 0.420 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.580 0.420 0.000
Q40 Other congenital malformations of upper alimentary tract
0.580 0.420 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.580 0.420 0.000
F41.1 Generalised anxiety disorder
0.579 0.421 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.579 0.421 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.578 0.422 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.578 0.422 0.000
G53.0 Postzoster neuralgia
0.577 0.423 0.000
F12.1 Harmful use
0.577 0.423 0.000
Q83 Congenital malformations of breast
0.577 0.423 0.000
M92 Other juvenile osteochondrosis
0.577 0.423 0.000
M54.12 Radiculopathy (Cervical region)
0.576 0.424 0.000
Q18 Other congenital malformations of face and neck
0.574 0.426 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.573 0.427 0.000
Q82 Other congenital malformations of skin
0.572 0.428 0.000
M33 Dermatopolymyositis
0.571 0.429 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.571 0.429 0.000
U50 Level of care administered to neonates
0.571 0.429 0.000
U07 Emergency use of U07
0.571 0.429 0.000
U06 Emergency use of U06
0.571 0.429 0.000
U04 Severe acute respiratory syndrome [SARS]
0.571 0.429 0.000
U52 First in a series of a regular day/night admissions
0.571 0.429 0.000
F19.9 Unspecified mental and behavioural disorder
0.571 0.429 0.000
F19.8 Other mental and behavioural disorders
0.571 0.429 0.000
F19.7 Residual and late-onset psychotic disorder
0.571 0.429 0.000
F19.6 Amnesic syndrome
0.571 0.429 0.000
F19.5 Psychotic disorder
0.571 0.429 0.000
F19.4 Withdrawal state with delirium
0.571 0.429 0.000
F19.3 Withdrawal state
0.571 0.429 0.000
F19.0 Acute intoxication
0.571 0.429 0.000
Q79.6 Ehlers-Danlos syndrome
0.570 0.430 0.000
A15-A19 Tuberculosis
0.570 0.430 0.000
G50.9 Disorder of trigeminal nerve, unspecified
0.570 0.430 0.000
G50.8 Other disorders of trigeminal nerve
0.570 0.430 0.000
Q67.5 Congenital deformity of spine
0.570 0.430 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.570 0.430 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.569 0.431 0.000
M13.93 Arthritis, unspecified (Forearm)
0.569 0.431 0.000
F64 Gender identity disorders
0.569 0.431 0.000
G91.0 Communicating hydrocephalus
0.566 0.434 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.566 0.434 0.000
Q99 Other chromosome abnormalities, not elsewhere classified
0.565 0.435 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.565 0.435 0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified
0.565 0.435 0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified
0.565 0.435 0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified
0.565 0.435 0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified
0.565 0.435 0.000
Q91 Edwards' syndrome and Patau's syndrome
0.565 0.435 0.000
Q90 Down's syndrome
0.565 0.435 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.565 0.435 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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