TreeWAS – Variant ID: rs17639982

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I30-I52 Other forms of heart disease	0.162	0.838	0.000
I34 Nonrheumatic mitral valve disorders	0.160	0.840	0.000
I34.0 Mitral (valve) insufficiency	0.156	0.844	0.000
I51 Complications and ill-defined descriptions of heart disease	0.150	0.850	0.000
I46 Cardiac arrest	0.147	0.853	0.000
I51.8 Other ill-defined heart diseases	0.143	0.857	0.000
I35 Nonrheumatic aortic valve disorders	0.138	0.862	0.000
I42 Cardiomyopathy	0.134	0.866	0.000
I46.0 Cardiac arrest with successful resuscitation	0.130	0.870	0.000
I50 Heart failure	0.128	0.872	0.000
I49 Other cardiac arrhythmias	0.128	0.872	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.127	0.873	0.000
I34.1 Mitral (valve) prolapse	0.127	0.873	0.000
I31 Other diseases of pericardium	0.124	0.876	0.000
I44 Atrioventricular and left bundle-branch block	0.124	0.876	0.000
I35.0 Aortic (valve) stenosis	0.123	0.877	0.000
I46.9 Cardiac arrest, unspecified	0.121	0.879	0.000
I36 Nonrheumatic tricuspid valve disorders	0.120	0.880	0.000
I38 Endocarditis, valve unspecified	0.119	0.881	0.000
I50.0 Congestive heart failure	0.118	0.882	0.000
I51.0 Cardiac septal defect, acquired	0.117	0.883	0.000
I52 Other heart disorders in diseases classified elsewhere	0.116	0.884	0.000
I48 Atrial fibrillation and flutter	0.116	0.884	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.116	0.884	0.000
I41 Myocarditis in diseases classified elsewhere	0.116	0.884	0.000
I40 Acute myocarditis	0.116	0.884	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.116	0.884	0.000
I37 Pulmonary valve disorders	0.116	0.884	0.000
I32 Pericarditis in diseases classified elsewhere	0.116	0.884	0.000
I30 Acute pericarditis	0.116	0.884	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.115	0.885	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.115	0.885	0.000
I51.6 Cardiovascular disease, unspecified	0.108	0.892	0.000
I51.5 Myocardial degeneration	0.108	0.892	0.000
I51.4 Myocarditis, unspecified	0.108	0.892	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.108	0.892	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.108	0.892	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.108	0.892	0.000
I47 Paroxysmal tachycardia	0.107	0.893	0.000
I31.9 Disease of pericardium, unspecified	0.107	0.893	0.000
I45 Other conduction disorders	0.107	0.893	0.000
I33 Acute and subacute endocarditis	0.106	0.894	0.000
I46.1 Sudden cardiac death, so described	0.106	0.894	0.000
I35.9 Aortic valve disorder, unspecified	0.106	0.894	0.000
I44.1 Atrioventricular block, second degree	0.105	0.895	0.000
I42.8 Other cardiomyopathies	0.104	0.896	0.000
I42.9 Cardiomyopathy, unspecified	0.103	0.897	0.000
I51.9 Heart disease, unspecified	0.103	0.897	0.000
I49.9 Cardiac arrhythmia, unspecified	0.103	0.897	0.000
I49.5 Sick sinus syndrome	0.102	0.898	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.101	0.899	0.000
I42.2 Other hypertrophic cardiomyopathy	0.101	0.899	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.101	0.899	0.000
I49.0 Ventricular fibrillation and flutter	0.100	0.900	0.000
I35.8 Other aortic valve disorders	0.098	0.902	0.000
I44.6 Other and unspecified fascicular block	0.097	0.902	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.096	0.904	0.000
I42.6 Alcoholic cardiomyopathy	0.096	0.904	0.000
I42.5 Other restrictive cardiomyopathy	0.096	0.904	0.000
I42.4 Endocardial fibroelastosis	0.096	0.904	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.096	0.904	0.000
I42.0 Dilated cardiomyopathy	0.094	0.906	0.000
I44.3 Other and unspecified atrioventricular block	0.093	0.907	0.000
I49.2 Junctional premature depolarisation	0.092	0.908	0.000
I49.3 Ventricular premature depolarisation	0.090	0.910	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.089	0.910	0.000
I51.7 Cardiomegaly	0.089	0.911	0.000
I31.8 Other specified diseases of pericardium	0.089	0.911	0.000
I31.2 Haemopericardium, not elsewhere classified	0.089	0.911	0.000
I31.1 Chronic constrictive pericarditis	0.089	0.911	0.000
I31.0 Chronic adhesive pericarditis	0.089	0.911	0.000
I44.5 Left posterior fascicular block	0.089	0.911	0.000
I44.4 Left anterior fascicular block	0.089	0.911	0.000
I49.4 Other and unspecified premature depolarisation	0.089	0.911	0.000
I49.1 Atrial premature depolarisation	0.088	0.911	0.000
I47.0 Reentry ventricular arrhythmia	0.088	0.912	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.086	0.914	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.086	0.914	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.086	0.914	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.086	0.914	0.000
I60-I69 Cerebrovascular diseases	0.085	0.915	0.000
I35.1 Aortic (valve) insufficiency	0.085	0.915	0.000
I50.9 Heart failure, unspecified	0.085	0.915	0.000
Chapter IX Diseases of the circulatory system	0.084	0.916	0.000
I44.7 Left bundle-branch block, unspecified	0.084	0.916	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.083	0.916	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.083	0.916	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.083	0.916	0.000
I37.9 Pulmonary valve disorder, unspecified	0.083	0.916	0.000
I37.8 Other pulmonary valve disorders	0.083	0.916	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.083	0.916	0.000
I37.1 Pulmonary valve insufficiency	0.083	0.916	0.000
I37.0 Pulmonary valve stenosis	0.083	0.916	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.083	0.916	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.083	0.916	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.083	0.916	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.083	0.916	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.083	0.916	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.083	0.916	0.000
I40.9 Acute myocarditis, unspecified	0.083	0.916	0.000
I40.8 Other acute myocarditis	0.083	0.916	0.000
I40.1 Isolated myocarditis	0.083	0.916	0.000
I40.0 Infective myocarditis	0.083	0.916	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.083	0.916	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.083	0.916	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.083	0.916	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.083	0.916	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.083	0.916	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.083	0.916	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.083	0.916	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.083	0.916	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.083	0.916	0.000
I48.4 Atypical atrial flutter	0.083	0.916	0.000
I48.3 Typical atrial flutter	0.083	0.916	0.000
I48.2 Chronic atrial fibrillation	0.083	0.916	0.000
I48.1 Persistent atrial fibrillation	0.083	0.916	0.000
I48.0 Paroxysmal atrial fibrillation	0.083	0.916	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.083	0.916	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.083	0.916	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.083	0.916	0.000
I45.9 Conduction disorder, unspecified	0.083	0.916	0.000
I30.8 Other forms of acute pericarditis	0.083	0.916	0.000
I30.1 Infective pericarditis	0.083	0.916	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.083	0.916	0.000
I30.9 Acute pericarditis, unspecified	0.083	0.917	0.000
I44.0 Atrioventricular block, first degree	0.080	0.920	0.000
I61 Intracerebral haemorrhage	0.080	0.920	0.000
I49.8 Other specified cardiac arrhythmias	0.079	0.921	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.078	0.922	0.000
I45.5 Other specified heart block	0.077	0.922	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.078	0.922	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.077	0.923	0.000
I45.8 Other specified conduction disorders	0.077	0.923	0.000
I45.4 Nonspecific intraventricular block	0.077	0.923	0.000
I45.3 Trifascicular block	0.077	0.923	0.000
I45.2 Bifascicular block	0.077	0.923	0.000
I45.0 Right fascicular block	0.077	0.923	0.000
I33.9 Acute endocarditis, unspecified	0.076	0.924	0.000
I65.2 Occlusion and stenosis of carotid artery	0.074	0.926	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.072	0.928	0.000
I44.2 Atrioventricular block, complete	0.072	0.928	0.000
I63 Cerebral infarction	0.071	0.929	0.000
I05-I09 Chronic rheumatic heart diseases	0.070	0.930	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.070	0.930	0.000
I45.1 Other and unspecified right bundle-branch block	0.069	0.931	0.000
I31.3 Pericardial effusion (noninflammatory)	0.068	0.931	0.000
I47.2 Ventricular tachycardia	0.068	0.932	0.000
I62 Other nontraumatic intracranial haemorrhage	0.068	0.932	0.000
I33.0 Acute and subacute infective endocarditis	0.066	0.934	0.000
I45.6 Preexcitation syndrome	0.065	0.934	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.065	0.935	0.000
I63.9 Cerebral infarction, unspecified	0.062	0.938	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.062	0.938	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.061	0.939	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.061	0.939	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.060	0.940	0.000
I00-I02 Acute rheumatic fever	0.060	0.940	0.000
I74 Arterial embolism and thrombosis	0.060	0.940	0.000
I72 Other aneurysm	0.060	0.940	0.000
I47.1 Supraventricular tachycardia	0.060	0.940	0.000
I50.1 Left ventricular failure	0.058	0.942	0.000
I61.8 Other intracerebral haemorrhage	0.057	0.942	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.057	0.942	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.057	0.942	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.057	0.942	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.057	0.942	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.057	0.942	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.056	0.944	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.056	0.944	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.056	0.944	0.000
I65.1 Occlusion and stenosis of basilar artery	0.056	0.944	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.056	0.944	0.000
I05 Rheumatic mitral valve diseases	0.056	0.944	0.000
I70 Atherosclerosis	0.055	0.945	0.000
I07 Rheumatic tricuspid valve diseases	0.054	0.946	0.000
I08 Multiple valve diseases	0.054	0.946	0.000
I77 Other disorders of arteries and arterioles	0.054	0.946	0.000
I60 Subarachnoid haemorrhage	0.053	0.947	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.053	0.947	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.052	0.948	0.000
I74.5 Embolism and thrombosis of iliac artery	0.051	0.949	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.051	0.949	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.051	0.949	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.051	0.949	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.051	0.949	0.000
I09 Other rheumatic heart diseases	0.051	0.949	0.000
I06 Rheumatic aortic valve diseases	0.051	0.949	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.050	0.950	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.050	0.950	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.049	0.951	0.000
I62.1 Nontraumatic extradural haemorrhage	0.049	0.951	0.000
I72.3 Aneurysm of iliac artery	0.048	0.952	0.000
I72.4 Aneurysm of artery of lower extremity	0.048	0.952	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.048	0.952	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.047	0.953	0.000
I67 Other cerebrovascular diseases	0.047	0.953	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.046	0.954	0.000
I72.8 Aneurysm of other specified arteries	0.046	0.954	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.046	0.954	0.000
I77.8 Other specified disorders of arteries and arterioles	0.045	0.954	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.045	0.955	0.000
I05.0 Mitral stenosis	0.045	0.955	0.000
I08.0 Disorders of both mitral and aortic valves	0.045	0.955	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.045	0.955	0.000
I71 Aortic aneurysm and dissection	0.044	0.956	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.044	0.956	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.044	0.956	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.044	0.956	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.044	0.956	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.044	0.956	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.044	0.956	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.044	0.956	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.044	0.956	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.044	0.956	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.044	0.956	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.044	0.956	0.000
I68.0 Cerebral amyloid angiopathy	0.044	0.956	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.044	0.956	0.000
I02 Rheumatic chorea	0.043	0.956	0.000
I01 Rheumatic fever with heart involvement	0.043	0.956	0.000
I00 Rheumatic fever without mention of heart involvement	0.043	0.956	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.043	0.957	0.000
I74.8 Embolism and thrombosis of other arteries	0.043	0.957	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.043	0.957	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.043	0.957	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.043	0.957	0.000
I72.9 Aneurysm of unspecified site	0.043	0.957	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.043	0.957	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.043	0.957	0.000
I72.2 Aneurysm of renal artery	0.043	0.957	0.000
I72.1 Aneurysm of artery of upper extremity	0.043	0.957	0.000
I72.0 Aneurysm of carotid artery	0.043	0.957	0.000
I78 Diseases of capillaries	0.043	0.957	0.000
I77.1 Stricture of artery	0.043	0.957	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.043	0.957	0.000
I07.1 Tricuspid insufficiency	0.042	0.958	0.000
I05.9 Mitral valve disease, unspecified	0.042	0.958	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.042	0.958	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.042	0.958	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.041	0.959	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.041	0.959	0.000
I05.8 Other mitral valve diseases	0.040	0.960	0.000
I05.2 Mitral stenosis with insufficiency	0.040	0.960	0.000
I05.1 Rheumatic mitral insufficiency	0.040	0.960	0.000
I63.8 Other cerebral infarction	0.040	0.960	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.040	0.960	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.040	0.960	0.000
I70.0 Atherosclerosis of aorta	0.039	0.960	0.000
I70.9 Generalised and unspecified atherosclerosis	0.039	0.961	0.000
I70.8 Atherosclerosis of other arteries	0.039	0.961	0.000
I70.1 Atherosclerosis of renal artery	0.039	0.961	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.039	0.961	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.039	0.961	0.000
I07.9 Tricuspid valve disease, unspecified	0.039	0.961	0.000
I07.8 Other tricuspid valve diseases	0.039	0.961	0.000
I07.2 Tricuspid stenosis with insufficiency	0.039	0.961	0.000
I07.0 Tricuspid stenosis	0.039	0.961	0.000
I08.9 Multiple valve disease, unspecified	0.039	0.961	0.000
I08.8 Other multiple valve diseases	0.039	0.961	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.039	0.961	0.000
I77.5 Necrosis of artery	0.039	0.961	0.000
I77.4 Coeliac artery compression syndrome	0.039	0.961	0.000
I77.3 Arterial fibromuscular dysplasia	0.039	0.961	0.000
I77.2 Rupture of artery	0.039	0.961	0.000
I77.0 Arteriovenous fistula, acquired	0.039	0.961	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.039	0.961	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.039	0.961	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.038	0.961	0.000
I60.8 Other subarachnoid haemorrhage	0.038	0.962	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.038	0.962	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.038	0.962	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.038	0.962	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.038	0.962	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.038	0.962	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.038	0.962	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.038	0.962	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.038	0.962	0.000
I67.9 Cerebrovascular disease, unspecified	0.038	0.962	0.000
T39.0 Salicylates	0.038	0.962	0.000
I69 Sequelae of cerebrovascular disease	0.037	0.962	0.000
T42.4 Benzodiazepines	0.037	0.963	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.036	0.963	0.000
I06.8 Other rheumatic aortic valve diseases	0.036	0.963	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.036	0.963	0.000
I06.1 Rheumatic aortic insufficiency	0.036	0.963	0.000
I06.0 Rheumatic aortic stenosis	0.036	0.963	0.000
I09.9 Rheumatic heart disease, unspecified	0.036	0.963	0.000
I09.8 Other specified rheumatic heart diseases	0.036	0.963	0.000
I09.2 Chronic rheumatic pericarditis	0.036	0.963	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.036	0.963	0.000
I09.0 Rheumatic myocarditis	0.036	0.963	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.036	0.964	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.036	0.964	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.036	0.964	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.036	0.964	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.036	0.964	0.000
I79.1 Aortitis in diseases classified elsewhere	0.036	0.964	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.036	0.964	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.036	0.964	0.000
I99 Other and unspecified disorders of circulatory system	0.036	0.964	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.036	0.964	0.000
T39.1 4-Aminophenol derivatives	0.036	0.964	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.035	0.964	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.035	0.965	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.035	0.965	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.035	0.965	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.035	0.965	0.000
T36 Poisoning by systemic antibiotics	0.035	0.965	0.000
I87 Other disorders of veins	0.035	0.965	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.035	0.965	0.000
I97.1 Other functional disturbances following cardiac surgery	0.034	0.966	0.000
T40.2 Other opioids	0.034	0.966	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.034	0.966	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.034	0.966	0.000
I67.5 Moyamoya disease	0.034	0.966	0.000
I67.4 Hypertensive encephalopathy	0.034	0.966	0.000
I67.3 Progressive vascular leukoencephalopathy	0.034	0.966	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.034	0.966	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.034	0.966	0.000
I82 Other venous embolism and thrombosis	0.034	0.966	0.000
I28 Other diseases of pulmonary vessels	0.033	0.967	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.033	0.967	0.000
T40.6 Other and unspecified narcotics	0.033	0.967	0.000
K22.7 Barrett's oesophagus	0.000	0.967	0.033
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.033	0.967	0.000
I89.0 Lymphoedema, not elsewhere classified	0.033	0.967	0.000
T43.9 Psychotropic drug, unspecified	0.032	0.967	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.032	0.967	0.000
T43.6 Psychostimulants with abuse potential	0.032	0.967	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.032	0.967	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.032	0.967	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.032	0.968	0.000
T43.2 Other and unspecified antidepressants	0.032	0.968	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.032	0.968	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.032	0.968	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.032	0.968	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.032	0.968	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.032	0.968	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.032	0.968	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.032	0.968	0.000
T39.4 Antirheumatics, not elsewhere classified	0.032	0.968	0.000
T39.2 Pyrazolone derivatives	0.032	0.968	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.032	0.968	0.000
I71.0 Dissection of aorta [any part]	0.032	0.968	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.032	0.968	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.031	0.968	0.000
I01.8 Other acute rheumatic heart disease	0.031	0.968	0.000
I01.2 Acute rheumatic myocarditis	0.031	0.968	0.000
I01.1 Acute rheumatic endocarditis	0.031	0.968	0.000
I01.0 Acute rheumatic pericarditis	0.031	0.968	0.000
I02.9 Rheumatic chorea without heart involvement	0.031	0.968	0.000
I02.0 Rheumatic chorea with heart involvement	0.031	0.968	0.000
T45.5 Anticoagulants	0.031	0.968	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.031	0.969	0.000
I77.6 Arteritis, unspecified	0.031	0.969	0.000
I78.9 Disease of capillaries, unspecified	0.031	0.969	0.000
I78.8 Other diseases of capillaries	0.031	0.969	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.031	0.969	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.031	0.969	0.000
I73 Other peripheral vascular diseases	0.031	0.969	0.000
I27 Other pulmonary heart diseases	0.031	0.969	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.031	0.969	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.031	0.969	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.031	0.969	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.031	0.969	0.000
T42.3 Barbiturates	0.031	0.969	0.000
T42.2 Succinimides and oxazolidinediones	0.031	0.969	0.000
T42.1 Iminostilbenes	0.031	0.969	0.000
T42.0 Hydantoin derivatives	0.031	0.969	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.031	0.969	0.000
I67.2 Cerebral atherosclerosis	0.030	0.969	0.000
I86 Varicose veins of other sites	0.031	0.969	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.030	0.970	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.030	0.970	0.000
I88 Nonspecific lymphadenitis	0.030	0.970	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.030	0.970	0.000
T40.8 Lysergide [LSD]	0.030	0.970	0.000
T40.7 Cannabis (derivatives)	0.030	0.970	0.000
T40.5 Cocaine	0.030	0.970	0.000
T40.4 Other synthetic narcotics	0.030	0.970	0.000
T40.3 Methadone	0.030	0.970	0.000
T40.1 Heroin	0.030	0.970	0.000
T40.0 Opium	0.030	0.970	0.000
I67.1 Cerebral aneurysm, nonruptured	0.029	0.970	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.029	0.970	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.029	0.970	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.029	0.970	0.000
I97.0 Postcardiotomy syndrome	0.029	0.970	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.029	0.971	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.029	0.971	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.029	0.971	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.029	0.971	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.029	0.971	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.029	0.971	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.029	0.971	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.029	0.971	0.000
T44.0 Anticholinesterase agents	0.029	0.971	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.028	0.971	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.028	0.971	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.028	0.971	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.028	0.971	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.028	0.971	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.028	0.971	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.028	0.971	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.028	0.971	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.028	0.971	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.028	0.971	0.000
T46.7 Peripheral vasodilators	0.028	0.971	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.028	0.971	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.028	0.971	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.028	0.971	0.000
T46.1 Calcium-channel blockers	0.028	0.971	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.028	0.971	0.000
T38.9 Other and unspecified hormone antagonists	0.028	0.972	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.028	0.972	0.000
T38.7 Androgens and anabolic congeners	0.028	0.972	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.028	0.972	0.000
T38.5 Other oestrogens and progestogens	0.028	0.972	0.000
T38.4 Oral contraceptives	0.028	0.972	0.000
T38.2 Antithyroid drugs	0.028	0.972	0.000
T38.1 Thyroid hormones and substitutes	0.028	0.972	0.000
T38.0 Glucocorticoids and synthetic analogues	0.028	0.972	0.000
T50.8 Diagnostic agents	0.028	0.972	0.000
T50.7 Analeptics and opioid receptor antagonists	0.028	0.972	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.028	0.972	0.000
T50.5 Appetite depressants	0.028	0.972	0.000
T50.4 Drugs affecting uric acid metabolism	0.028	0.972	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.028	0.972	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.028	0.972	0.000
T50.1 Loop [high-ceiling] diuretics	0.028	0.972	0.000
T50.0 Mineralocorticoids and their antagonists	0.028	0.972	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.028	0.972	0.000
T45.8 Other primarily systemic and haematological agents	0.028	0.972	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.028	0.972	0.000
T45.6 Fibrinolysis-affecting drugs	0.028	0.972	0.000
T45.4 Iron and its compounds	0.028	0.972	0.000
T45.3 Enzymes, not elsewhere classified	0.028	0.972	0.000
T45.2 Vitamins, not elsewhere classified	0.028	0.972	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.028	0.972	0.000
T45.0 Antiallergic and antiemetic drugs	0.028	0.972	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.028	0.972	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.028	0.972	0.000
T47.7 Emetics	0.028	0.972	0.000
T47.6 Antidiarrhoeal drugs	0.028	0.972	0.000
T47.5 Digestants	0.028	0.972	0.000
T47.4 Other laxatives	0.028	0.972	0.000
T47.3 Saline and osmotic laxatives	0.028	0.972	0.000
T47.2 Stimulant laxatives	0.028	0.972	0.000
T47.0 Histamine H(2)-receptor antagonists	0.028	0.972	0.000
I83 Varicose veins of lower extremities	0.028	0.972	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.027	0.973	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.027	0.973	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.027	0.973	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.027	0.973	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.027	0.973	0.000
I81 Portal vein thrombosis	0.027	0.973	0.000
I82.8 Embolism and thrombosis of other specified veins	0.027	0.973	0.000
I10-I15 Hypertensive diseases	0.027	0.973	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.026	0.974	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.026	0.974	0.000
I89.1 Lymphangitis	0.026	0.974	0.000
I85 Oesophageal varices	0.026	0.974	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.026	0.974	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.026	0.974	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.026	0.974	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.026	0.974	0.000
I98.0 Cardiovascular syphilis	0.026	0.974	0.000
T36.9 Systemic antibiotic, unspecified	0.025	0.974	0.000
T36.8 Other systemic antibiotics	0.025	0.974	0.000
T36.7 Antifungal antibiotics, systemically used	0.025	0.974	0.000
T36.6 Rifamycins	0.025	0.974	0.000
T36.5 Aminoglycosides	0.025	0.974	0.000
T36.4 Tetracyclines	0.025	0.974	0.000
T36.3 Macrolides	0.025	0.974	0.000
T36.2 Chloramphenicol group	0.025	0.974	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.025	0.974	0.000
T36.0 Penicillins	0.025	0.974	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.025	0.974	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.025	0.974	0.000
T37.5 Antiviral drugs	0.025	0.974	0.000
T37.4 Anthelminthics	0.025	0.974	0.000
T37.3 Other antiprotozoal drugs	0.025	0.974	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.025	0.974	0.000
T37.1 Antimycobacterial drugs	0.025	0.974	0.000
T37.0 Sulphonamides	0.025	0.974	0.000
T41.5 Therapeutic gases	0.025	0.974	0.000
T41.4 Anaesthetic, unspecified	0.025	0.974	0.000
T41.3 Local anaesthetics	0.025	0.974	0.000
T41.2 Other and unspecified general anaesthetics	0.025	0.974	0.000
T41.1 Intravenous anaesthetics	0.025	0.974	0.000
T41.0 Inhaled anaesthetics	0.025	0.974	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.025	0.974	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.025	0.974	0.000
T48.5 Anti-common-cold drugs	0.025	0.974	0.000
T48.4 Expectorants	0.025	0.974	0.000
T48.3 Antitussives	0.025	0.974	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.025	0.974	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.025	0.974	0.000
T48.0 Oxytocic drugs	0.025	0.974	0.000
T49.9 Topical agent, unspecified	0.025	0.974	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations