TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs1811197
log Bayes Factor = 124.907
Chromosome 6   position 31,327,660  (GRCh37) Explore rs1811197 on Ensembl!
Variant rs1811197 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
D69 Purpura and other haemorrhagic conditions
1.000 0.000 0.000
D64.9 Anaemia, unspecified
0.999 0.001 0.000
D80-D89 Certain disorders involving the immune mechanism
0.999 0.001 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.999 0.001 0.000
E14.3 With ophthalmic complications
0.999 0.001 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.999 0.001 0.000
D69.6 Thrombocytopenia, unspecified
0.999 0.001 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.001 0.999
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.999 0.001 0.000
E10.1 With ketoacidosis
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
K70-K77 Diseases of liver
0.998 0.002 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.997 0.003 0.000
E20-E35 Disorders of other endocrine glands
0.997 0.003 0.000
I73 Other peripheral vascular diseases
0.996 0.004 0.000
K75 Other inflammatory liver diseases
0.996 0.004 0.000
D86 Sarcoidosis
0.995 0.005 0.000
K75.4 Autoimmune hepatitis
0.995 0.005 0.000
D50-D53 Nutritional anaemias
0.995 0.005 0.000
N40 Hyperplasia of prostate
0.000 0.007 0.993
C85.1 B-cell lymphoma, unspecified
0.992 0.008 0.000
E10.2 With renal complications
0.992 0.008 0.000
I73.0 Raynaud's syndrome
0.992 0.008 0.000
N40-N51 Diseases of male genital organs
0.000 0.011 0.989
E89.0 Postprocedural hypothyroidism
0.989 0.011 0.000
Chapter XI Diseases of the digestive system
0.988 0.011 0.000
E50-E64 Other nutritional deficiencies
0.988 0.012 0.000
E70-E90 Metabolic disorders
0.987 0.013 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.986 0.014 0.000
K40 Inguinal hernia
0.001 0.014 0.985
D50 Iron deficiency anaemia
0.986 0.014 0.000
M34 Systemic sclerosis
0.985 0.015 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.982 0.018 0.000
D86.9 Sarcoidosis, unspecified
0.982 0.018 0.000
E27 Other disorders of adrenal gland
0.982 0.018 0.000
E27.1 Primary adrenocortical insufficiency
0.980 0.020 0.000
G56.0 Carpal tunnel syndrome
0.980 0.020 0.000
D61 Other aplastic anaemias
0.980 0.020 0.000
H36.0 Diabetic retinopathy
0.979 0.021 0.000
Chapter VI Diseases of the nervous system
0.976 0.024 0.000
K72 Hepatic failure, not elsewhere classified
0.976 0.024 0.000
H36 Retinal disorders in diseases classified elsewhere
0.974 0.026 0.000
K73 Chronic hepatitis, not elsewhere classified
0.974 0.026 0.000
H30-H36 Disorders of choroid and retina
0.971 0.029 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.971 0.029 0.000
Chapter VII Diseases of the eye and adnexa
0.970 0.030 0.000
G56 Mononeuropathies of upper limb
0.970 0.030 0.000
E16 Other disorders of pancreatic internal secretion
0.970 0.030 0.000
D50.9 Iron deficiency anaemia, unspecified
0.969 0.031 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.966 0.034 0.000
D61.9 Aplastic anaemia, unspecified
0.965 0.035 0.000
K40-K46 Hernia
0.010 0.037 0.953
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.962 0.038 0.000
I74 Arterial embolism and thrombosis
0.960 0.040 0.000
E16.2 Hypoglycaemia, unspecified
0.959 0.041 0.000
E06 Thyroiditis
0.957 0.043 0.000
K44 Diaphragmatic hernia
0.003 0.043 0.954
N42 Other disorders of prostate
0.000 0.043 0.957
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.045 0.955
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.952 0.048 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.049 0.951
C81 Hodgkin's disease
0.950 0.050 0.000
I73.9 Peripheral vascular disease, unspecified
0.946 0.054 0.000
I60-I69 Cerebrovascular diseases
0.945 0.055 0.000
E21.3 Hyperparathyroidism, unspecified
0.942 0.058 0.000
I63 Cerebral infarction
0.942 0.058 0.000
K72.0 Acute and subacute hepatic failure
0.941 0.059 0.000
M21 Other acquired deformities of limbs
0.940 0.060 0.000
M15-M19 Arthrosis
0.936 0.064 0.000
E55 Vitamin D deficiency
0.936 0.064 0.000
D80 Immunodeficiency with predominantly antibody defects
0.935 0.065 0.000
E06.3 Autoimmune thyroiditis
0.928 0.072 0.000
N42.8 Other specified disorders of prostate
0.000 0.072 0.928
E10.4 With neurological complications
0.928 0.072 0.000
H34 Retinal vascular occlusions
0.926 0.074 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.923 0.077 0.000
E53 Deficiency of other B group vitamins
0.923 0.077 0.000
C83.3 Large cell (diffuse)
0.922 0.078 0.000
D69.4 Other primary thrombocytopenia
0.921 0.079 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.918 0.082 0.000
I10-I15 Hypertensive diseases
0.918 0.082 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.916 0.084 0.000
N45 Orchitis and epididymitis
0.000 0.085 0.915
D51 Vitamin B12 deficiency anaemia
0.915 0.085 0.000
K50-K52 Noninfective enteritis and colitis
0.910 0.090 0.000
D86.0 Sarcoidosis of lung
0.910 0.090 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.908 0.091 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.907 0.093 0.000
K52 Other non-infective gastro-enteritis and colitis
0.906 0.094 0.000
I12 Hypertensive renal disease
0.903 0.097 0.000
K73.9 Chronic hepatitis, unspecified
0.902 0.098 0.000
E55.9 Vitamin D deficiency, unspecified
0.899 0.101 0.000
M32 Systemic lupus erythematosus
0.898 0.102 0.000
M21.0 Valgus deformity, not elsewhere classified
0.897 0.103 0.000
E03.8 Other specified hypothyroidism
0.894 0.106 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.892 0.108 0.000
E14.8 With unspecified complications
0.889 0.111 0.000
E73 Lactose intolerance
0.889 0.111 0.000
Chapter XIV Diseases of the genitourinary system
0.883 0.112 0.005
M34.9 Systemic sclerosis, unspecified
0.887 0.113 0.000
N00-N08 Glomerular diseases
0.884 0.116 0.000
M18 Arthrosis of first carpometacarpal joint
0.884 0.116 0.000
M00-M03 Infectious arthropathies
0.883 0.117 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.118 0.882
M15 Polyarthrosis
0.882 0.118 0.000
H34.8 Other retinal vascular occlusions
0.882 0.118 0.000
C91 Lymphoid leukaemia
0.881 0.119 0.000
I12.9 Hypertensive renal disease without renal failure
0.880 0.120 0.000
M34.1 CR(E)ST syndrome
0.878 0.122 0.000
E53.8 Deficiency of other specified B group vitamins
0.878 0.122 0.000
N17-N19 Renal failure
0.874 0.126 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.866 0.134 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.865 0.135 0.000
G30-G32 Other degenerative diseases of the nervous system
0.865 0.135 0.000
K74 Fibrosis and cirrhosis of liver
0.865 0.135 0.000
N04 Nephrotic syndrome
0.864 0.136 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.864 0.136 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.862 0.138 0.000
M60-M63 Disorders of muscles
0.861 0.139 0.000
N18 Chronic renal failure
0.861 0.139 0.000
M34.8 Other forms of systemic sclerosis
0.860 0.140 0.000
N48 Other disorders of penis
0.000 0.140 0.860
M35.7 Hypermobility syndrome
0.859 0.141 0.000
K90-K93 Other diseases of the digestive system
0.858 0.142 0.000
E24 Cushing's syndrome
0.857 0.143 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.856 0.144 0.000
C88 Malignant immunoproliferative diseases
0.851 0.149 0.000
K90 Intestinal malabsorption
0.851 0.149 0.000
D50.8 Other iron deficiency anaemias
0.850 0.150 0.000
D64.8 Other specified anaemias
0.850 0.150 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.849 0.151 0.000
E07 Other disorders of thyroid
0.849 0.151 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.151 0.849
K75.8 Other specified inflammatory liver diseases
0.846 0.154 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.846 0.154 0.000
N41 Inflammatory diseases of prostate
0.000 0.157 0.843
E14.2 Withrenal complications
0.843 0.157 0.000
N04.9 Unspecified
0.842 0.158 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.158 0.842
G51 Facial nerve disorders
0.842 0.158 0.000
C81.9 Hodgkin's disease, unspecified
0.840 0.160 0.000
L50-L54 Urticaria and erythema
0.837 0.163 0.000
N18.9 Chronic renal failure, unspecified
0.836 0.164 0.000
N05 Unspecified nephritic syndrome
0.835 0.165 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.835 0.165 0.000
K72.9 Hepatic failure, unspecified
0.835 0.165 0.000
D69.5 Secondary thrombocytopenia
0.830 0.170 0.000
M17 Gonarthrosis [arthrosis of knee]
0.830 0.170 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.825 0.175 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.825 0.175 0.000
H30 Chorioretinal inflammation
0.825 0.175 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.824 0.176 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.823 0.177 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.823 0.177 0.000
I74.8 Embolism and thrombosis of other arteries
0.822 0.178 0.000
E10.7 With multiple complications
0.821 0.179 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.821 0.179 0.000
M33 Dermatopolymyositis
0.820 0.180 0.000
D69.2 Other nonthrombocytopenic purpura
0.819 0.181 0.000
M17.1 Other primary gonarthrosis
0.819 0.181 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.819 0.181 0.000
E73.9 Lactose intolerance, unspecified
0.819 0.181 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.817 0.183 0.000
C83.1 Small cleaved cell (diffuse)
0.815 0.185 0.000
K70 Alcoholic liver disease
0.815 0.185 0.000
K90.9 Intestinal malabsorption, unspecified
0.815 0.185 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.814 0.186 0.000
M65-M68 Disorders of synovium and tendon
0.813 0.187 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.812 0.188 0.000
N48.1 Balanoposthitis
0.000 0.189 0.811
E88 Other metabolic disorders
0.809 0.191 0.000
D55-D59 Haemolytic anaemias
0.809 0.191 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.809 0.191 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.808 0.192 0.000
L10-L14 Bullous disorders
0.807 0.193 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.807 0.193 0.000
G81 Hemiplegia
0.806 0.194 0.000
M34.0 Progressive systemic sclerosis
0.806 0.194 0.000
M21.8 Other specified acquired deformities of limbs
0.805 0.195 0.000
C81.1 Nodular sclerosis
0.799 0.201 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.798 0.202 0.000
H05 Disorders of orbit
0.795 0.205 0.000
M86-M90 Other osteopathies
0.793 0.207 0.000
H06.2 Dysthyroid exophthalmos
0.793 0.207 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.791 0.209 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.791 0.209 0.000
I12.0 Hypertensive renal disease with renal failure
0.791 0.209 0.000
E10.8 With unspecified complications
0.791 0.209 0.000
N05.2 Diffuse membranous glomerulonephritis
0.789 0.211 0.000
M00 Pyogenic arthritis
0.789 0.211 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.788 0.212 0.000
C84.5 Other and unspecified T-cell lymphomas
0.787 0.213 0.000
D50.1 Sideropenic dysphagia
0.786 0.214 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.215 0.785
E10.0 With coma
0.783 0.217 0.000
D83 Common variable immunodeficiency
0.782 0.218 0.000
I63.9 Cerebral infarction, unspecified
0.782 0.218 0.000
E10.5 With peripheral circulatory complications
0.782 0.218 0.000
E13 Other specified diabetes mellitus
0.780 0.220 0.000
E14.5 With peripheral circulatory complications
0.780 0.220 0.000
C92 Myeloid leukaemia
0.779 0.221 0.000
L52 Erythema nodosum
0.778 0.222 0.000
I62 Other nontraumatic intracranial haemorrhage
0.778 0.222 0.000
N44 Torsion of testis
0.000 0.222 0.778
C83.0 Small cell (diffuse)
0.777 0.223 0.000
C83.7 Burkitt's tumour
0.777 0.223 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.777 0.223 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.776 0.224 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.774 0.226 0.000
C81.2 Mixed cellularity
0.772 0.227 0.000
C91.1 Chronic lymphocytic leukaemia
0.772 0.228 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.771 0.229 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.771 0.229 0.000
I77 Other disorders of arteries and arterioles
0.771 0.229 0.000
L13 Other bullous disorders
0.770 0.230 0.000
C86 Other specified types of T/NK-cell lymphoma
0.769 0.231 0.000
E31 Polyglandular dysfunction
0.768 0.232 0.000
E51 Thiamine deficiency
0.768 0.232 0.000
Q50-Q56 Congenital malformations of genital organs
0.768 0.232 0.000
I63.8 Other cerebral infarction
0.766 0.234 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.765 0.235 0.000
E14.1 With ketoacidosis
0.764 0.236 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.763 0.237 0.000
G81.9 Hemiplegia, unspecified
0.762 0.238 0.000
D86.1 Sarcoidosis of lymph nodes
0.761 0.238 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.761 0.239 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.760 0.240 0.000
E14.6 With other specified complications
0.759 0.241 0.000
N18.4 Chronic kidney disease, stage 4
0.758 0.242 0.000
D86.3 Sarcoidosis of skin
0.757 0.243 0.000
D69.9 Haemorrhagic condition, unspecified
0.756 0.244 0.000
E24.2 Drug-induced Cushing's syndrome
0.755 0.245 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.752 0.248 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.751 0.248 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.749 0.251 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.749 0.251 0.000
G51.9 Disorder of facial nerve, unspecified
0.748 0.252 0.000
M30 Polyarteritis nodosa and related conditions
0.748 0.252 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.744 0.256 0.000
N46 Male infertility
0.000 0.256 0.744
D61.1 Drug-induced aplastic anaemia
0.744 0.256 0.000
L13.0 Dermatitis herpetiformis
0.744 0.256 0.000
L50 Urticaria
0.743 0.257 0.000
M35.1 Other overlap syndromes
0.742 0.258 0.000
G52 Disorders of other cranial nerves
0.742 0.258 0.000
Q00-Q07 Congenital malformations of the nervous system
0.740 0.260 0.000
N18.1 Chronic kidney disease, stage 1
0.739 0.261 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.738 0.262 0.000
E61 Deficiency of other nutrient elements
0.738 0.262 0.000
K74.6 Other and unspecified cirrhosis of liver
0.737 0.263 0.000
I11 Hypertensive heart disease
0.736 0.264 0.000
H34.2 Other retinal artery occlusions
0.734 0.266 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.731 0.269 0.000
N17 Acute renal failure
0.731 0.269 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.730 0.270 0.000
E05.8 Other thyrotoxicosis
0.730 0.270 0.000
N41.1 Chronic prostatitis
0.000 0.270 0.730
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.271 0.729
E22 Hyperfunction of pituitary gland
0.728 0.272 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.728 0.272 0.000
C81.0 Lymphocytic predominance
0.728 0.272 0.000
M66 Spontaneous rupture of synovium and tendon
0.726 0.274 0.000
N48.4 Impotence of organic origin
0.000 0.275 0.725
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.723 0.277 0.000
D84 Other immunodeficiencies
0.723 0.277 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.723 0.277 0.000
E40-E46 Malnutrition
0.722 0.278 0.000
K72.1 Chronic hepatic failure
0.722 0.278 0.000
G31.8 Other specified degenerative diseases of nervous system
0.721 0.279 0.000
H30.9 Chorioretinal inflammation, unspecified
0.721 0.279 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.718 0.282 0.000
M62 Other disorders of muscle
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.8 Other specified systemic involvement of connective tissue
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
D69.8 Other specified haemorrhagic conditions
0.717 0.283 0.000
D69.1 Qualitative platelet defects
0.717 0.283 0.000
D82 Immunodeficiency associated with other major defects
0.716 0.283 0.000
D81 Combined immunodeficiencies
0.716 0.283 0.000
D67 Hereditary factor IX deficiency
0.716 0.283 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.716 0.283 0.000
C85.0 Lymphosarcoma
0.716 0.283 0.000
D86.8 Sarcoidosis of other and combined sites
0.716 0.284 0.000
K74.3 Primary biliary cirrhosis
0.716 0.284 0.000
K77 Liver disorders in diseases classified elsewhere
0.716 0.284 0.000
K71 Toxic liver disease
0.716 0.284 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.715 0.285 0.000
C94 Other leukaemias of specified cell type
0.715 0.285 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.715 0.285 0.000
E32 Diseases of thymus
0.715 0.285 0.000
E30 Disorders of puberty, not elsewhere classified
0.715 0.285 0.000
K75.2 Nonspecific reactive hepatitis
0.714 0.286 0.000
K75.1 Phlebitis of portal vein
0.714 0.286 0.000
G12 Spinal muscular atrophy and related syndromes
0.714 0.286 0.000
C84.0 Mycosis fungoides
0.714 0.286 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.714 0.286 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.713 0.287 0.000
M00.9 Pyogenic arthritis, unspecified
0.713 0.287 0.000
N25-N29 Other disorders of kidney and ureter
0.711 0.288 0.001
E11 Non-insulin-dependent diabetes mellitus
0.711 0.289 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.710 0.290 0.000
L53 Other erythematous conditions
0.710 0.290 0.000
M15.8 Other polyarthrosis
0.710 0.290 0.000
G51.0 Bell's palsy
0.709 0.291 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.291 0.709
H05.2 Exophthalmic conditions
0.708 0.291 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.708 0.292 0.000
E63 Other nutritional deficiencies
0.708 0.292 0.000
E56 Other vitamin deficiencies
0.708 0.292 0.000
E50 Vitamin A deficiency
0.708 0.292 0.000
E60 Dietary zinc deficiency
0.708 0.292 0.000
E59 Dietary selenium deficiency
0.708 0.292 0.000
E54 Ascorbic acid deficiency
0.708 0.292 0.000
E52 Niacin deficiency [pellagra]
0.708 0.292 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.002 0.293 0.706
E84 Cystic fibrosis
0.707 0.293 0.000
E79 Disorders of purine and pyrimidine metabolism
0.707 0.293 0.000
E77 Disorders of glycoprotein metabolism
0.707 0.293 0.000
E76 Disorders of glycosaminoglycan metabolism
0.707 0.293 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.707 0.293 0.000
E72 Other disorders of amino-acid metabolism
0.707 0.293 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.707 0.293 0.000
E70 Disorders of aromatic amino-acid metabolism
0.707 0.293 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.707 0.293 0.000
E25 Adrenogenital disorders
0.707 0.293 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.707 0.293 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.707 0.293 0.000
E89.5 Postprocedural testicular hypofunction
0.707 0.293 0.000
E89.4 Postprocedural ovarian failure
0.707 0.293 0.000
E89.1 Postprocedural hypoinsulinaemia
0.707 0.293 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.001 0.293 0.706
K40.1 Bilateral inguinal hernia, with gangrene
0.001 0.293 0.706
Q43 Other congenital malformations of intestine
0.707 0.293 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.706 0.294 0.000
H34.1 Central retinal artery occlusion
0.706 0.294 0.000
G35 Multiple sclerosis
0.705 0.295 0.000
E15 Nondiabetic hypoglycaemic coma
0.704 0.296 0.000
E27.5 Adrenomedullary hyperfunction
0.704 0.296 0.000
E27.0 Other adrenocortical overactivity
0.704 0.296 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.703 0.297 0.000
M15.4 Erosive (osteo)arthrosis
0.703 0.297 0.000
D61.8 Other specified aplastic anaemias
0.703 0.297 0.000
D61.3 Idiopathic aplastic anaemia
0.703 0.297 0.000
D61.2 Aplastic anaemia due to other external agents
0.703 0.297 0.000
E24.0 Pituitary-dependent Cushing's disease
0.702 0.298 0.000
I95 Hypotension
0.702 0.298 0.000
D53 Other nutritional anaemias
0.700 0.300 0.000
Q65 Congenital deformities of hip
0.699 0.301 0.000
H55-H59 Other disorders of eye and adnexa
0.699 0.301 0.000
C93 Monocytic leukaemia
0.698 0.302 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.698 0.302 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.698 0.302 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.698 0.302 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.698 0.302 0.000
N48.5 Ulcer of penis
0.000 0.302 0.697
C91.4 Hairy-cell leukaemia
0.697 0.303 0.000
C91.9 Lymphoid leukaemia, unspecified
0.697 0.303 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.696 0.304 0.000
G56.4 Causalgia
0.696 0.304 0.000
D63.0 Anaemia in neoplastic disease
0.695 0.305 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.695 0.305 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.695 0.305 0.000
E16.4 Abnormal secretion of gastrin
0.695 0.305 0.000
E16.3 Increased secretion of glucagon
0.695 0.305 0.000
M15.1 Heberden's nodes (with arthropathy)
0.695 0.305 0.000
I00-I02 Acute rheumatic fever
0.695 0.305 0.000
E58 Dietary calcium deficiency
0.693 0.306 0.000
K70.9 Alcoholic liver disease, unspecified
0.693 0.307 0.000
E23 Hypofunction and other disorders of pituitary gland
0.693 0.307 0.000
N18.2 Chronic kidney disease, stage 2
0.693 0.307 0.000
C83.6 Undifferentiated (diffuse)
0.692 0.307 0.000
C83.5 Lymphoblastic (diffuse)
0.692 0.307 0.000
C83.4 Immunoblastic (diffuse)
0.692 0.307 0.000
C83.2 Mixed small and large cell (diffuse)
0.692 0.307 0.000
M60 Myositis
0.692 0.308 0.000
M33.1 Other dermatomyositis
0.692 0.308 0.000
E88.8 Other specified metabolic disorders
0.692 0.308 0.000
E10.6 With other specified complications
0.691 0.308 0.000
E14.4 With neurological complications
0.690 0.310 0.000
E21.4 Other specified disorders of parathyroid gland
0.690 0.310 0.000
E21.2 Other hyperparathyroidism
0.690 0.310 0.000
E14.9 Without complications
0.690 0.310 0.000
E07.8 Other specified disorders of thyroid
0.689 0.311 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.688 0.312 0.000
E29 Testicular dysfunction
0.688 0.312 0.000
N42.0 Calculus of prostate
0.000 0.312 0.688
E07.9 Disorder of thyroid, unspecified
0.687 0.313 0.000
G54 Nerve root and plexus disorders
0.687 0.313 0.000
E06.5 Other chronic thyroiditis
0.686 0.314 0.000
E06.4 Drug-induced thyroiditis
0.686 0.314 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.686 0.314 0.000
E06.1 Subacute thyroiditis
0.686 0.314 0.000
E06.0 Acute thyroiditis
0.686 0.314 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.686 0.314 0.000
N42.3 Dysplasia of prostate
0.000 0.314 0.686
K46 Unspecified abdominal hernia
0.005 0.314 0.681
M15.9 Polyarthrosis, unspecified
0.686 0.314 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.685 0.314 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.684 0.316 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.683 0.317 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.682 0.318 0.000
E20 Hypoparathyroidism
0.681 0.318 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.681 0.319 0.000
C81.7 Other Hodgkin's disease
0.681 0.319 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.681 0.319 0.000
C81.3 Lymphocytic depletion
0.681 0.319 0.000
N04.2 Diffuse membranous glomerulonephritis
0.681 0.319 0.000
C95 Leukaemia of unspecified cell type
0.681 0.319 0.000
N00 Acute nephritic syndrome
0.680 0.319 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.679 0.321 0.000
I95.2 Hypotension due to drugs
0.679 0.321 0.000
K52.3 Indeterminate colitis
0.678 0.322 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.678 0.322 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.677 0.323 0.000
D61.0 Constitutional aplastic anaemia
0.675 0.325 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.675 0.325 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.675 0.325 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.675 0.325 0.000
M40-M43 Deforming dorsopathies
0.675 0.325 0.000
K44.1 Diaphragmatic hernia with gangrene
0.002 0.325 0.672
E28 Ovarian dysfunction
0.674 0.326 0.000
M21.9 Acquired deformity of limb, unspecified
0.674 0.326 0.000
M89 Other disorders of bone
0.674 0.326 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.673 0.327 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.672 0.327 0.000
N18.0 End-stage renal disease
0.672 0.328 0.000
N48.2 Other inflammatory disorders of penis
0.000 0.328 0.672
G70-G73 Diseases of myoneural junction and muscle
0.671 0.329 0.000
E55.0 Rickets, active
0.671 0.329 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.670 0.329 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.670 0.329 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.670 0.329 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.670 0.329 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.670 0.329 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.670 0.329 0.000
E06.9 Thyroiditis, unspecified
0.669 0.331 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.669 0.331 0.000
Q76 Congenital malformations of spine and bony thorax
0.667 0.333 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.665 0.335 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.665 0.335 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.664 0.336 0.000
L94 Other localised connective tissue disorders
0.664 0.336 0.000
H34.0 Transient retinal artery occlusion
0.664 0.336 0.000
L93 Lupus erythematosus
0.664 0.336 0.000
H05.0 Acute inflammation of orbit
0.663 0.337 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.663 0.337 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.663 0.337 0.000
I79.1 Aortitis in diseases classified elsewhere
0.662 0.338 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.662 0.338 0.000
E53.1 Pyridoxine deficiency
0.662 0.338 0.000
E53.0 Riboflavin deficiency
0.662 0.338 0.000
Q51 Congenital malformations of uterus and cervix
0.661 0.339 0.000
M02 Reactive arthropathies
0.659 0.341 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.659 0.341 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2024 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.