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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs181424343
log Bayes Factor = 5.27138
Chromosome 1   position 218,594,484  (GRCh37) Explore rs181424343 on Ensembl!
Variant rs181424343 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
M15-M19 Arthrosis
0.996 0.004 0.000
M20-M25 Other joint disorders
0.996 0.004 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.991 0.009 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.967 0.033 0.000
I83 Varicose veins of lower extremities
0.965 0.035 0.000
I30-I52 Other forms of heart disease
0.963 0.037 0.000
M17 Gonarthrosis [arthrosis of knee]
0.962 0.038 0.000
Chapter XIV Diseases of the genitourinary system
0.958 0.042 0.000
Chapter II Neoplasms
0.956 0.044 0.000
Chapter VII Diseases of the eye and adnexa
0.944 0.056 0.000
M25 Other joint disorders, not elsewhere classified
0.941 0.059 0.000
Chapter I Certain infectious and parasitic diseases
0.937 0.063 0.000
M20 Acquired deformities of fingers and toes
0.936 0.064 0.000
N30-N39 Other diseases of urinary system
0.932 0.068 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.927 0.073 0.000
N10-N16 Renal tubulo-interstitial diseases
0.925 0.075 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.920 0.080 0.000
M16 Coxarthrosis [arthrosis of hip]
0.915 0.085 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.911 0.089 0.000
M17.1 Other primary gonarthrosis
0.908 0.092 0.000
D10-D36 Benign neoplasms
0.905 0.095 0.000
C15-C26 Malignant neoplasms of digestive organs
0.904 0.096 0.000
M25.5 Pain in joint
0.904 0.096 0.000
I35 Nonrheumatic aortic valve disorders
0.900 0.100 0.000
N30 Cystitis
0.888 0.112 0.000
C18 Malignant neoplasm of colon
0.887 0.113 0.000
M20.1 Hallux valgus (acquired)
0.882 0.118 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.881 0.119 0.000
I38 Endocarditis, valve unspecified
0.879 0.121 0.000
I47 Paroxysmal tachycardia
0.876 0.124 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.876 0.124 0.000
M23 Internal derangement of knee
0.876 0.124 0.000
D17 Benign lipomatous neoplasm
0.871 0.129 0.000
I80 Phlebitis and thrombophlebitis
0.868 0.132 0.000
M05-M14 Inflammatory polyarthropathies
0.868 0.132 0.000
M19 Other arthrosis
0.862 0.138 0.000
H53-H54 Visual disturbances and blindness
0.862 0.138 0.000
M25.51 Pain in joint (Shoulder region)
0.861 0.139 0.000
I26 Pulmonary embolism
0.853 0.147 0.000
S60-S69 Injuries to the wrist and hand
0.847 0.153 0.000
M80-M85 Disorders of bone density and structure
0.845 0.155 0.000
I81 Portal vein thrombosis
0.845 0.155 0.000
M22 Disorders of patella
0.845 0.155 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.841 0.159 0.000
O60-O75 Complications of labour and delivery
0.841 0.159 0.000
B15-B19 Viral hepatitis
0.833 0.167 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.831 0.169 0.000
M16.1 Other primary coxarthrosis
0.826 0.174 0.000
I34 Nonrheumatic mitral valve disorders
0.825 0.175 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.823 0.177 0.000
M23.3 Other meniscus derangements
0.822 0.178 0.000
S40-S49 Injuries to the shoulder and upper arm
0.821 0.179 0.000
C18.7 Sigmoid colon
0.819 0.181 0.000
M16.9 Coxarthrosis, unspecified
0.813 0.187 0.000
M18 Arthrosis of first carpometacarpal joint
0.812 0.188 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.812 0.188 0.000
M13 Other arthritis
0.803 0.197 0.000
S70-S79 Injuries to the hip and thigh
0.801 0.199 0.000
I35.1 Aortic (valve) insufficiency
0.799 0.201 0.000
N30.2 Other chronic cystitis
0.799 0.201 0.000
N20-N23 Urolithiasis
0.799 0.201 0.000
N13 Obstructive and reflux uropathy
0.799 0.201 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.797 0.203 0.000
O72 Postpartum haemorrhage
0.795 0.205 0.000
I47.1 Supraventricular tachycardia
0.795 0.205 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.794 0.206 0.000
I35.0 Aortic (valve) stenosis
0.793 0.207 0.000
N39 Other disorders of urinary system
0.791 0.209 0.000
A30-A49 Other bacterial diseases
0.791 0.209 0.000
I85 Oesophageal varices
0.791 0.209 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.790 0.210 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.788 0.212 0.000
M17.0 Primary gonarthrosis, bilateral
0.787 0.213 0.000
N36 Other disorders of urethra
0.784 0.216 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.782 0.218 0.000
N30.8 Other cystitis
0.782 0.218 0.000
I33 Acute and subacute endocarditis
0.777 0.223 0.000
S80-S89 Injuries to the knee and lower leg
0.776 0.224 0.000
C18.0 Caecum
0.774 0.226 0.000
Chapter X Diseases of the respiratory system
0.773 0.227 0.000
D00-D09 In situ neoplasms
0.773 0.227 0.000
M31 Other necrotising vasculopathies
0.770 0.230 0.000
M17.9 Gonarthrosis, unspecified
0.768 0.232 0.000
Chapter VIII Diseases of the ear and mastoid process
0.766 0.234 0.000
O72.1 Other immediate postpartum haemorrhage
0.763 0.237 0.000
I71 Aortic aneurysm and dissection
0.763 0.237 0.000
I86 Varicose veins of other sites
0.761 0.239 0.000
O80-O84 Delivery
0.759 0.241 0.000
C18.2 Ascending colon
0.759 0.241 0.000
H43-H45 Disorders of vitreous body and globe
0.759 0.241 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.758 0.241 0.000
M13.9 Arthritis, unspecified
0.757 0.243 0.000
M86-M90 Other osteopathies
0.756 0.244 0.000
M19.9 Arthrosis, unspecified
0.756 0.244 0.000
N20 Calculus of kidney and ureter
0.748 0.252 0.000
M91-M94 Chondropathies
0.747 0.253 0.000
H53 Visual disturbances
0.747 0.253 0.000
D22 Melanocytic naevi
0.746 0.254 0.000
N99-N99 Other disorders of the genitourinary system
0.746 0.254 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.744 0.256 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.744 0.256 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.741 0.259 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.741 0.259 0.000
A00-A09 Intestinal infectious diseases
0.741 0.259 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.740 0.260 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.739 0.261 0.000
M20.2 Hallux rigidus
0.738 0.262 0.000
H54 Blindness and low vision
0.738 0.262 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.737 0.263 0.000
N39.4 Other specified urinary incontinence
0.735 0.265 0.000
M81 Osteoporosis without pathological fracture
0.735 0.265 0.000
I89.0 Lymphoedema, not elsewhere classified
0.734 0.266 0.000
M20.3 Other deformity of hallux (acquired)
0.734 0.266 0.000
C16 Malignant neoplasm of stomach
0.734 0.266 0.000
M25.54 Pain in joint (Hand)
0.734 0.266 0.000
Chapter VI Diseases of the nervous system
0.733 0.267 0.000
D18 Haemangioma and lymphangioma, any site
0.730 0.270 0.000
S64 Injury of nerves at wrist and hand level
0.729 0.270 0.000
M20.5 Other deformities of toe(s) (acquired)
0.729 0.271 0.000
D32 Benign neoplasm of meninges
0.726 0.274 0.000
I31 Other diseases of pericardium
0.725 0.275 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.724 0.276 0.000
J95-J99 Other diseases of the respiratory system
0.723 0.277 0.000
I05-I09 Chronic rheumatic heart diseases
0.722 0.278 0.000
Chapter XX External causes of morbidity and mortality
0.722 0.278 0.000
M22.4 Chondromalacia patellae
0.721 0.279 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.720 0.280 0.000
I49 Other cardiac arrhythmias
0.719 0.281 0.000
S20-S29 Injuries to the thorax
0.719 0.281 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
N25-N29 Other disorders of kidney and ureter
0.717 0.283 0.000
C64-C68 Malignant neoplasms of urinary tract
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
I78 Diseases of capillaries
0.715 0.284 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.715 0.285 0.000
H40-H42 Glaucoma
0.715 0.285 0.000
I74 Arterial embolism and thrombosis
0.714 0.286 0.000
M15 Polyarthrosis
0.714 0.286 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.714 0.286 0.000
M34 Systemic sclerosis
0.714 0.286 0.000
M33 Dermatopolymyositis
0.714 0.286 0.000
M32 Systemic lupus erythematosus
0.714 0.286 0.000
M30 Polyarteritis nodosa and related conditions
0.714 0.286 0.000
M21 Other acquired deformities of limbs
0.714 0.286 0.000
C25 Malignant neoplasm of pancreas
0.713 0.286 0.000
I88 Nonspecific lymphadenitis
0.710 0.290 0.000
I87 Other disorders of veins
0.710 0.290 0.000
I82 Other venous embolism and thrombosis
0.710 0.290 0.000
M25.56 Pain in joint (Lower leg)
0.710 0.290 0.000
N35 Urethral stricture
0.709 0.291 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.707 0.293 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.706 0.294 0.000
B17 Other acute viral hepatitis
0.703 0.297 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.702 0.298 0.000
M45-M49 Spondylopathies
0.701 0.298 0.000
D23 Other benign neoplasms of skin
0.700 0.300 0.000
H55-H59 Other disorders of eye and adnexa
0.698 0.301 0.000
B18 Chronic viral hepatitis
0.698 0.302 0.000
D24 Benign neoplasm of breast
0.696 0.304 0.000
M40-M43 Deforming dorsopathies
0.694 0.305 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.694 0.306 0.000
T79-T79 Certain early complications of trauma
0.693 0.307 0.000
T66-T78 Other and unspecified effects of external causes
0.693 0.307 0.000
T33-T35 Frostbite
0.693 0.307 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.693 0.307 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.693 0.307 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.693 0.307 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.693 0.307 0.000
T00-T07 Injuries involving multiple body regions
0.693 0.307 0.000
S10-S19 Injuries to the neck
0.693 0.307 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.693 0.307 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.692 0.308 0.000
S90-S99 Injuries to the ankle and foot
0.692 0.308 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.692 0.308 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.692 0.308 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.692 0.308 0.000
H10-H13 Disorders of conjunctiva
0.690 0.310 0.000
I52 Other heart disorders in diseases classified elsewhere
0.690 0.310 0.000
I48 Atrial fibrillation and flutter
0.690 0.310 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.690 0.310 0.000
I41 Myocarditis in diseases classified elsewhere
0.690 0.310 0.000
I40 Acute myocarditis
0.690 0.310 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.690 0.310 0.000
I37 Pulmonary valve disorders
0.690 0.310 0.000
I36 Nonrheumatic tricuspid valve disorders
0.690 0.310 0.000
I32 Pericarditis in diseases classified elsewhere
0.690 0.310 0.000
I30 Acute pericarditis
0.690 0.310 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.690 0.310 0.000
M17.5 Other secondary gonarthrosis
0.689 0.310 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.689 0.310 0.000
M17.3 Other posttraumatic gonarthrosis
0.689 0.310 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.689 0.310 0.000
M25.4 Effusion of joint
0.689 0.311 0.000
C18.9 Colon, unspecified
0.688 0.312 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.687 0.313 0.000
J98 Other respiratory disorders
0.687 0.313 0.000
I34.0 Mitral (valve) insufficiency
0.687 0.313 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.685 0.315 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.685 0.315 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.685 0.315 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.685 0.315 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.685 0.315 0.000
I47.2 Ventricular tachycardia
0.685 0.315 0.000
N20.1 Calculus of ureter
0.684 0.316 0.000
S72 Fracture of femur
0.683 0.317 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.681 0.319 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.679 0.321 0.000
S60 Superficial injury of wrist and hand
0.678 0.322 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.677 0.323 0.000
N13.4 Hydroureter
0.676 0.324 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.675 0.325 0.000
H25-H28 Disorders of lens
0.675 0.325 0.000
M25.9 Joint disorder, unspecified
0.675 0.325 0.000
M25.8 Other specified joint disorders
0.675 0.325 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.675 0.325 0.000
M25.3 Other instability of joint
0.675 0.325 0.000
M25.2 Flail joint
0.675 0.325 0.000
M25.1 Fistula of joint
0.675 0.325 0.000
M25.0 Haemarthrosis
0.675 0.325 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.673 0.327 0.000
B99-B99 Other infectious diseases
0.672 0.328 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.672 0.328 0.000
B65-B83 Helminthiases
0.672 0.328 0.000
B50-B64 Protozoal diseases
0.672 0.328 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.672 0.328 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.672 0.328 0.000
A80-A89 Viral infections of the central nervous system
0.672 0.328 0.000
A75-A79 Rickettsioses
0.672 0.328 0.000
A70-A74 Other diseases caused by chlamydiae
0.672 0.328 0.000
A65-A69 Other spirochaetal diseases
0.672 0.328 0.000
A20-A28 Certain zoonotic bacterial diseases
0.672 0.328 0.000
A15-A19 Tuberculosis
0.672 0.328 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.672 0.328 0.000
M20.0 Deformity of finger(s)
0.671 0.329 0.000
N13.3 Other and unspecified hydronephrosis
0.671 0.329 0.000
O00-O08 Pregnancy with abortive outcome
0.670 0.330 0.000
N30.1 Interstitial cystitis (chronic)
0.669 0.331 0.000
N37 Urethral disorders in diseases classified elsewhere
0.668 0.332 0.000
N34 Urethritis and urethral syndrome
0.668 0.332 0.000
N33 Bladder disorders in diseases classified elsewhere
0.668 0.332 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.667 0.333 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.665 0.335 0.000
M25.53 Pain in joint (Forearm)
0.665 0.335 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.663 0.337 0.000
N15 Other renal tubulo-interstitial diseases
0.663 0.337 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.663 0.337 0.000
N11 Chronic tubulo-interstitial nephritis
0.663 0.337 0.000
N10 Acute tubulo-interstitial nephritis
0.663 0.337 0.000
M23.8 Other internal derangements of knee
0.661 0.339 0.000
D23.7 Skin of lower limb, including hip
0.660 0.340 0.000
S68 Traumatic amputation of wrist and hand
0.660 0.340 0.000
O85-O92 Complications predominantly related to the puerperium
0.660 0.340 0.000
I45 Other conduction disorders
0.659 0.341 0.000
D27 Benign neoplasm of ovary
0.658 0.342 0.000
I34.1 Mitral (valve) prolapse
0.658 0.342 0.000
M16.7 Other secondary coxarthrosis
0.656 0.344 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.656 0.344 0.000
M16.5 Other posttraumatic coxarthrosis
0.656 0.344 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.656 0.344 0.000
M16.3 Other dysplastic coxarthrosis
0.656 0.344 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.656 0.344 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.655 0.345 0.000
M35 Other systemic involvement of connective tissue
0.654 0.346 0.000
M24 Other specific joint derangements
0.653 0.346 0.000
I28 Other diseases of pulmonary vessels
0.653 0.347 0.000
N30.9 Cystitis, unspecified
0.653 0.347 0.000
A40 Streptococcal septicaemia
0.651 0.349 0.000
M65-M68 Disorders of synovium and tendon
0.650 0.349 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.649 0.351 0.000
D31 Benign neoplasm of eye and adnexa
0.649 0.351 0.000
D30 Benign neoplasm of urinary organs
0.649 0.351 0.000
D29 Benign neoplasm of male genital organs
0.649 0.351 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.649 0.351 0.000
D26 Other benign neoplasms of uterus
0.649 0.351 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.649 0.351 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.649 0.351 0.000
D19 Benign neoplasm of mesothelial tissue
0.649 0.351 0.000
D16 Benign neoplasm of bone and articular cartilage
0.649 0.351 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.649 0.351 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.649 0.351 0.000
D10 Benign neoplasm of mouth and pharynx
0.649 0.351 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.648 0.351 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.648 0.351 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.648 0.351 0.000
C21 Malignant neoplasm of anus and anal canal
0.648 0.351 0.000
C17 Malignant neoplasm of small intestine
0.648 0.351 0.000
C23 Malignant neoplasm of gallbladder
0.648 0.351 0.000
M25.59 Pain in joint (Site unspecified)
0.648 0.352 0.000
M25.58 Pain in joint (Other)
0.648 0.352 0.000
M25.52 Pain in joint (Upper arm)
0.648 0.352 0.000
D11 Benign neoplasm of major salivary glands
0.648 0.352 0.000
I85.9 Oesophageal varices without bleeding
0.647 0.353 0.000
D22.5 Melanocytic naevi of trunk
0.647 0.353 0.000
I35.9 Aortic valve disorder, unspecified
0.645 0.354 0.000
I35.8 Other aortic valve disorders
0.645 0.354 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.645 0.354 0.000
C60-C63 Malignant neoplasms of male genital organs
0.644 0.356 0.000
D34 Benign neoplasm of thyroid gland
0.644 0.356 0.000
I33.0 Acute and subacute infective endocarditis
0.644 0.356 0.000
M19.0 Primary arthrosis of other joints
0.643 0.357 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.642 0.358 0.000
M25.7 Osteophyte
0.641 0.359 0.000
S50-S59 Injuries to the elbow and forearm
0.640 0.359 0.000
A04 Other bacterial intestinal infections
0.641 0.359 0.000
M25.50 Pain in joint (Multiple sites)
0.640 0.360 0.000
H53.0 Amblyopia ex anopsia
0.640 0.360 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.639 0.361 0.000
N36.8 Other specified disorders of urethra
0.639 0.361 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.639 0.361 0.000
B35-B49 Mycoses
0.639 0.361 0.000
B95-B98 Bacterial, viral and other infectious agents
0.639 0.361 0.000
J98.1 Pulmonary collapse
0.639 0.361 0.000
N30.4 Irradiation cystitis
0.637 0.363 0.000
N30.3 Trigonitis
0.637 0.363 0.000
N30.0 Acute cystitis
0.637 0.363 0.000
M05 Seropositive rheumatoid arthritis
0.636 0.363 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.636 0.364 0.000
C18.8 Overlapping lesion of colon
0.636 0.364 0.000
C18.6 Descending colon
0.636 0.364 0.000
C18.5 Splenic flexure
0.636 0.364 0.000
C18.4 Transverse colon
0.636 0.364 0.000
C18.3 Hepatic flexure
0.636 0.364 0.000
C18.1 Appendix
0.636 0.364 0.000
M22.2 Patellofemoral disorders
0.636 0.364 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.635 0.365 0.000
N20.0 Calculus of kidney
0.635 0.365 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.634 0.366 0.000
I27 Other pulmonary heart diseases
0.633 0.367 0.000
D04 Carcinoma in situ of skin
0.632 0.368 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.632 0.368 0.000
I72 Other aneurysm
0.632 0.368 0.000
I70 Atherosclerosis
0.632 0.368 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.629 0.371 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.628 0.372 0.000
I47.0 Reentry ventricular arrhythmia
0.628 0.372 0.000
M23.9 Internal derangement of knee, unspecified
0.628 0.372 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.628 0.372 0.000
M23.5 Chronic instability of knee
0.628 0.372 0.000
M23.4 Loose body in knee
0.628 0.372 0.000
M23.1 Discoid meniscus (congenital)
0.628 0.372 0.000
M23.0 Cystic meniscus
0.628 0.372 0.000
S40 Superficial injury of shoulder and upper arm
0.627 0.372 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.626 0.373 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.626 0.374 0.000
I31.9 Disease of pericardium, unspecified
0.625 0.375 0.000
I51 Complications and ill-defined descriptions of heart disease
0.625 0.375 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.624 0.375 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.624 0.375 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.624 0.376 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.623 0.377 0.000
N36.2 Urethral caruncle
0.623 0.377 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.622 0.377 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.622 0.377 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.622 0.377 0.000
M14 Arthropathies in other diseases classified elsewhere
0.622 0.378 0.000
M12 Other specific arthropathies
0.622 0.378 0.000
M11 Other crystal arthropathies
0.622 0.378 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.622 0.378 0.000
M08 Juvenile arthritis
0.622 0.378 0.000
M07 Psoriatic and enteropathic arthropathies
0.622 0.378 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.622 0.378 0.000
M81.9 Osteoporosis, unspecified
0.621 0.379 0.000
W20-W49 Exposure to inanimate mechanical forces
0.619 0.381 0.000
M19.8 Other specified arthrosis
0.618 0.382 0.000
M19.2 Other secondary arthrosis
0.618 0.382 0.000
M19.1 Posttraumatic arthrosis of other joints
0.618 0.382 0.000
H49 Paralytic strabismus
0.618 0.382 0.000
C15 Malignant neoplasm of oesophagus
0.618 0.382 0.000
O82 Single delivery by Caesarean section
0.618 0.382 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.617 0.383 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.617 0.383 0.000
H52 Disorders of refraction and accommodation
0.617 0.383 0.000
D05 Carcinoma in situ of breast
0.617 0.383 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.617 0.383 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.615 0.385 0.000
J90-J94 Other diseases of pleura
0.614 0.386 0.000
H44 Disorders of globe
0.612 0.388 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.612 0.388 0.000
C16.0 Cardia
0.611 0.389 0.000
B17.1 Acute hepatitis C
0.610 0.390 0.000
M31.6 Other giant cell arteritis
0.609 0.391 0.000
M25.57 Pain in joint (Ankle and foot)
0.609 0.391 0.000
S72.0 Fracture of neck of femur
0.609 0.391 0.000
H54.0 Blindness, both eyes
0.608 0.392 0.000
A49 Bacterial infection of unspecified site
0.608 0.392 0.000
S69 Other and unspecified injuries of wrist and hand
0.607 0.393 0.000
S67 Crushing injury of wrist and hand
0.607 0.393 0.000
S65 Injury of blood vessels at wrist and hand level
0.607 0.393 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.607 0.393 0.000
M85 Other disorders of bone density and structure
0.606 0.394 0.000
M84 Disorders of continuity of bone
0.606 0.394 0.000
M83 Adult osteomalacia
0.606 0.394 0.000
M82 Osteoporosis in diseases classified elsewhere
0.606 0.394 0.000
M80 Osteoporosis with pathological fracture
0.606 0.394 0.000
M22.1 Recurrent subluxation of patella
0.606 0.394 0.000
M22.9 Disorder of patella, unspecified
0.606 0.394 0.000
M22.8 Other disorders of patella
0.606 0.394 0.000
M22.3 Other derangements of patella
0.606 0.394 0.000
M22.0 Recurrent dislocation of patella
0.606 0.394 0.000
D18.0 Haemangioma, any site
0.605 0.395 0.000
B25-B34 Other viral diseases
0.604 0.395 0.000
O63 Long labour
0.604 0.396 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.603 0.397 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.603 0.397 0.000
I89.1 Lymphangitis
0.603 0.397 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.603 0.397 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.603 0.397 0.000
O74 Complications of anaesthesia during labour and delivery
0.603 0.397 0.000
O73 Retained placenta and membranes, without haemorrhage
0.603 0.397 0.000
O71 Other obstetric trauma
0.603 0.397 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.603 0.397 0.000
O66 Other obstructed labour
0.603 0.397 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.603 0.397 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.603 0.397 0.000
O62 Abnormalities of forces of labour
0.603 0.397 0.000
O61 Failed induction of labour
0.603 0.397 0.000
O60 Preterm delivery
0.603 0.397 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.603 0.397 0.000
I73 Other peripheral vascular diseases
0.601 0.399 0.000
I74.5 Embolism and thrombosis of iliac artery
0.601 0.399 0.000
B18.2 Chronic viral hepatitis C
0.601 0.399 0.000
M50-M54 Other dorsopathies
0.601 0.399 0.000
S89 Other and unspecified injuries of lower leg
0.600 0.400 0.000
H25 Senile cataract
0.599 0.401 0.000
N00-N08 Glomerular diseases
0.599 0.401 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.599 0.401 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.598 0.402 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.598 0.402 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.598 0.402 0.000
B19 Unspecified viral hepatitis
0.597 0.403 0.000
B16 Acute hepatitis B
0.597 0.403 0.000
B15 Acute hepatitis A
0.597 0.403 0.000
S42 Fracture of shoulder and upper arm
0.597 0.403 0.000
I78.1 Naevus, nonneoplastic
0.597 0.403 0.000
I86.1 Scrotal varices
0.596 0.404 0.000
S43.0 Dislocation of shoulder joint
0.596 0.404 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.596 0.404 0.000
H21 Other disorders of iris and ciliary body
0.596 0.404 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.595 0.405 0.000
H80-H83 Diseases of inner ear
0.595 0.405 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.595 0.405 0.000
B91 Sequelae of poliomyelitis
0.594 0.406 0.000
S80 Superficial injury of lower leg
0.592 0.408 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.591 0.409 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.591 0.409 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.591 0.409 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.590 0.410 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.590 0.410 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.590 0.410 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.590 0.410 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.590 0.410 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.590 0.410 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.590 0.410 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.590 0.410 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.590 0.410 0.000
T36 Poisoning by systemic antibiotics
0.590 0.410 0.000
M81.4 Drug-induced osteoporosis
0.590 0.410 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.589 0.411 0.000
M23.37 Other meniscus derangements-Capsular lig
0.589 0.411 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.589 0.411 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.589 0.411 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.589 0.411 0.000
H53.9 Visual disturbance, unspecified
0.588 0.412 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.588 0.412 0.000
S48 Traumatic amputation of shoulder and upper arm
0.588 0.412 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.588 0.412 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.588 0.412 0.000
S44 Injury of nerves at shoulder and upper arm level
0.588 0.412 0.000
S41 Open wound of shoulder and upper arm
0.588 0.412 0.000
S47 Crushing injury of shoulder and upper arm
0.588 0.412 0.000
A41 Other septicaemia
0.587 0.412 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.587 0.413 0.000
H30-H36 Disorders of choroid and retina
0.587 0.413 0.000
D32.9 Meninges, unspecified
0.586 0.414 0.000
O70 Perineal laceration during delivery
0.586 0.414 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.586 0.414 0.000
H60-H62 Diseases of external ear
0.584 0.416 0.000
O80 Single spontaneous delivery
0.584 0.416 0.000
T92 Sequelae of injuries of upper limb
0.583 0.417 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.582 0.418 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.582 0.418 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.582 0.418 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.582 0.418 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.582 0.418 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.582 0.418 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.582 0.418 0.000
I46 Cardiac arrest
0.581 0.419 0.000
N26 Unspecified contracted kidney
0.580 0.420 0.000
T51 Toxic effect of alcohol
0.579 0.421 0.000
D36 Benign neoplasm of other and unspecified sites
0.577 0.423 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.577 0.423 0.000
M13.8 Other specified arthritis
0.576 0.424 0.000
M13.1 Monoarthritis, not elsewhere classified
0.576 0.424 0.000
M13.0 Polyarthritis, unspecified
0.576 0.424 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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