TreeWAS – Variant ID: rs1868402

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.000	1.000
I83 Varicose veins of lower extremities	0.000	0.685	0.315
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.744	0.256
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.776	0.224
I69.3 Sequelae of cerebral infarction	0.212	0.788	0.000
I69 Sequelae of cerebrovascular disease	0.212	0.788	0.000
I61 Intracerebral haemorrhage	0.211	0.789	0.000
I63 Cerebral infarction	0.210	0.790	0.000
I60-I69 Cerebrovascular diseases	0.210	0.790	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.203	0.797	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.194	0.806	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.193	0.807	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.188	0.812	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.186	0.814	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.184	0.816	0.000
I60 Subarachnoid haemorrhage	0.182	0.818	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.181	0.819	0.000
I63.9 Cerebral infarction, unspecified	0.171	0.829	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.162	0.838	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.160	0.840	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.160	0.840	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.160	0.840	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.156	0.844	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.153	0.847	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.153	0.847	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.152	0.848	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.151	0.849	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.151	0.849	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.151	0.849	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.150	0.849	0.000
I63.8 Other cerebral infarction	0.150	0.850	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.149	0.851	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.149	0.851	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.147	0.853	0.000
I61.8 Other intracerebral haemorrhage	0.147	0.853	0.000
I60.8 Other subarachnoid haemorrhage	0.146	0.854	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.146	0.854	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.138	0.862	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.132	0.868	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.132	0.868	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.130	0.869	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.129	0.871	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.128	0.872	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.121	0.879	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.115	0.885	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.115	0.885	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.111	0.888	0.000
I68.0 Cerebral amyloid angiopathy	0.111	0.888	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.110	0.890	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.110	0.890	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.110	0.890	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.109	0.891	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.001	0.891	0.108
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.108	0.892	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.106	0.894	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.106	0.894	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.106	0.894	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.106	0.894	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.104	0.896	0.000
I65.2 Occlusion and stenosis of carotid artery	0.104	0.896	0.000
I65.1 Occlusion and stenosis of basilar artery	0.101	0.899	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.095	0.904	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.094	0.906	0.000
I67 Other cerebrovascular diseases	0.085	0.915	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.083	0.917	0.000
I67.2 Cerebral atherosclerosis	0.077	0.923	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.071	0.929	0.000
Z72.0 Tobacco use	0.070	0.930	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.061	0.939	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.061	0.939	0.000
I67.5 Moyamoya disease	0.061	0.939	0.000
I67.4 Hypertensive encephalopathy	0.061	0.939	0.000
I67.3 Progressive vascular leukoencephalopathy	0.061	0.939	0.000
I62 Other nontraumatic intracranial haemorrhage	0.061	0.939	0.001
I64 Stroke, not specified as haemorrhage or infarction	0.048	0.952	0.000
I62.1 Nontraumatic extradural haemorrhage	0.042	0.958	0.001
M48.09 Spinal stenosis (Site unspecified)	0.029	0.971	0.000
I67.1 Cerebral aneurysm, nonruptured	0.029	0.971	0.000
M48.0 Spinal stenosis	0.029	0.971	0.000
Z72 Problems related to lifestyle	0.028	0.972	0.000
M48.06 Spinal stenosis (Lumbar region)	0.026	0.974	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.026	0.974	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.026	0.974	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.024	0.975	0.001
Z72.1 Alcohol use	0.024	0.976	0.000
I67.9 Cerebrovascular disease, unspecified	0.024	0.976	0.000
M48.04 Spinal stenosis (Thoracic region)	0.022	0.978	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.022	0.978	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.021	0.979	0.000
F17.2 Dependence syndrome	0.021	0.979	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.021	0.979	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.021	0.979	0.000
Z72.9 Problem related to lifestyle, unspecified	0.020	0.980	0.000
Z72.6 Gambling and betting	0.020	0.980	0.000
Z72.5 High-risk sexual behaviour	0.020	0.980	0.000
Z72.3 Lack of physical exercise	0.020	0.980	0.000
H54.0 Blindness, both eyes	0.000	0.981	0.019
Z72.4 Inappropriate diet and eating habits	0.018	0.982	0.000
Z72.8 Other problems related to lifestyle	0.017	0.982	0.000
H54 Blindness and low vision	0.000	0.982	0.018
M48 Other spondylopathies	0.017	0.983	0.000
Z72.2 Drug use	0.016	0.984	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.984	0.016
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.016	0.984	0.001
H54.7 Unspecified visual loss	0.000	0.984	0.016
M48.8 Other specified spondylopathies	0.015	0.985	0.000
H54.6 Unqualified visual loss, one eye	0.000	0.986	0.013
I67.8 Other specified cerebrovascular diseases	0.013	0.987	0.000
H54.4 Blindness, one eye	0.000	0.987	0.013
H54.2 Low vision, both eyes	0.000	0.987	0.013
H54.3 Unqualified visual loss, both eyes	0.000	0.987	0.013
M48.9 Spondylopathy, unspecified	0.013	0.987	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.013	0.987	0.000
H54.5 Low vision, one eye	0.000	0.987	0.012
M48.4 Fatigue fracture of vertebra	0.012	0.988	0.000
M48.3 Traumatic spondylopathy	0.012	0.988	0.000
M48.2 Kissing spine	0.012	0.988	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.012	0.988	0.000
H54.1 Blindness, one eye, low vision, other eye	0.000	0.988	0.012
M48.5 Collapsed vertebra, not elsewhere classified	0.012	0.988	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.011	0.988	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.011	0.989	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.011	0.989	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.011	0.989	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.011	0.989	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.011	0.989	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.011	0.989	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.011	0.989	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.010	0.990	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.010	0.990	0.000
C16.9 Stomach, unspecified	0.010	0.990	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.009	0.990	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.009	0.990	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.009	0.990	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.009	0.990	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.009	0.990	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.009	0.990	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.009	0.990	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.009	0.990	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.009	0.991	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.009	0.991	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.009	0.991	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.009	0.991	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.009	0.991	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.009	0.991	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.009	0.991	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.009	0.991	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.009	0.991	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.009	0.991	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.009	0.991	0.000
M48.29 Kissing spine (Site unspecified)	0.009	0.991	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.009	0.991	0.000
M48.27 Kissing spine (Lumbosacral region)	0.009	0.991	0.000
M48.26 Kissing spine (Lumbar region)	0.009	0.991	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.009	0.991	0.000
M48.24 Kissing spine (Thoracic region)	0.009	0.991	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.009	0.991	0.000
M48.22 Kissing spine (Cervical region)	0.009	0.991	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.009	0.991	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.009	0.991	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.009	0.991	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.009	0.991	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.009	0.991	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.009	0.991	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.009	0.991	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.009	0.991	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.009	0.991	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.009	0.991	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.009	0.991	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.009	0.991	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.009	0.991	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.009	0.991	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.009	0.991	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.009	0.991	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.009	0.991	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.009	0.991	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.009	0.991	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.009	0.991	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.009	0.991	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.009	0.991	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.009	0.991	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.009	0.991	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.008	0.991	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.008	0.991	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.008	0.991	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.008	0.991	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.008	0.991	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.008	0.992	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.008	0.992	0.000
C16 Malignant neoplasm of stomach	0.008	0.992	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.008	0.992	0.000
C16.2 Body of stomach	0.007	0.993	0.000
C16.3 Pyloric antrum	0.007	0.993	0.000
M48.02 Spinal stenosis (Cervical region)	0.007	0.993	0.000
C16.5 Lesser curvature of stomach, unspecified	0.007	0.993	0.000
C16.8 Overlapping lesion of stomach	0.007	0.993	0.000
C16.6 Greater curvature of stomach, unspecified	0.007	0.993	0.000
C16.1 Fundus of stomach	0.006	0.994	0.000
C16.4 Pylorus	0.006	0.994	0.000
Q66 Congenital deformities of feet	0.006	0.994	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.006	0.994	0.000
Q65 Congenital deformities of hip	0.006	0.994	0.000
Q66.8 Other congenital deformities of feet	0.005	0.995	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.005	0.995	0.000
Q65.8 Other congenital deformities of hip	0.005	0.995	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.000	0.995	0.005
S82.30 Fracture of lower end of tibia (closed)	0.005	0.995	0.000
Q66.2 Metatarsus varus	0.005	0.995	0.000
Q76 Congenital malformations of spine and bony thorax	0.005	0.995	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.005	0.995	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
Q74 Other congenital malformations of limb(s)	0.005	0.995	0.000
Z50.5 Speech therapy	0.005	0.995	0.000
C16.0 Cardia	0.005	0.995	0.000
Q66.7 Pes cavus	0.005	0.995	0.000
Q66.3 Other congenital varus deformities of feet	0.005	0.995	0.000
Q78 Other osteochondrodysplasias	0.005	0.995	0.000
S82.10 Fracture of upper end of tibia (closed)	0.005	0.995	0.000
Q68 Other congenital musculoskeletal deformities	0.004	0.995	0.000
Q66.0 Talipes equinovarus	0.004	0.995	0.000
O36.8 Maternal care for other specified foetal problems	0.000	0.995	0.005
Q66.6 Other congenital valgus deformities of feet	0.004	0.995	0.000
Q66.5 Congenital pes planus	0.004	0.995	0.000
Q66.4 Talipes calcaneovalgus	0.004	0.995	0.000
Q66.1 Talipes calcaneovarus	0.004	0.995	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.995	0.000
Q75 Other congenital malformations of skull and face bones	0.004	0.995	0.000
Q73 Reduction defects of unspecified limb	0.004	0.995	0.000
Q72 Reduction defects of lower limb	0.004	0.995	0.000
Q71 Reduction defects of upper limb	0.004	0.995	0.000
Q70 Syndactyly	0.004	0.995	0.000
Q69 Polydactyly	0.004	0.995	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.996	0.004
C50.8 Overlapping lesion of breast	0.004	0.996	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.004	0.996	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.004	0.996	0.000
Q66.9 Congenital deformity of feet, unspecified	0.004	0.996	0.000
Q76.1 Klippel-Feil syndrome	0.004	0.996	0.000
Q65.9 Congenital deformity of hip, unspecified	0.004	0.996	0.000
Q65.6 Unstable hip	0.004	0.996	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.004	0.996	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.004	0.996	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.004	0.996	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.004	0.996	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.004	0.996	0.000
Q67.6 Pectus excavatum	0.004	0.996	0.000
Q67.5 Congenital deformity of spine	0.004	0.996	0.000
F17.9 Unspecified mental and behavioural disorder	0.004	0.996	0.000
F17.8 Other mental and behavioural disorders	0.004	0.996	0.000
F17.7 Residual and late-onset psychotic disorder	0.004	0.996	0.000
F17.6 Amnesic syndrome	0.004	0.996	0.000
F17.5 Psychotic disorder	0.004	0.996	0.000
F17.4 Withdrawal state with delirium	0.004	0.996	0.000
F17.3 Withdrawal state	0.004	0.996	0.000
Q74.1 Congenital malformation of knee	0.004	0.996	0.000
Q51.2 Other doubling of uterus	0.004	0.996	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.996	0.004
N92.3 Ovulation bleeding	0.004	0.996	0.000
F17.0 Acute intoxication	0.004	0.996	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.004	0.996	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.004	0.996	0.000
Q76.5 Cervical rib	0.004	0.996	0.000
Q51 Congenital malformations of uterus and cervix	0.004	0.996	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.004	0.996	0.000
Q76.8 Other congenital malformations of bony thorax	0.004	0.996	0.000
Q76.7 Congenital malformation of sternum	0.004	0.996	0.000
Q76.6 Other congenital malformations of ribs	0.004	0.996	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.004	0.996	0.000
Q76.2 Congenital spondylolisthesis	0.004	0.996	0.000
Q67.8 Other congenital deformities of chest	0.004	0.996	0.000
Q67.7 Pectus carinatum	0.004	0.996	0.000
Q67.3 Plagiocephaly	0.004	0.996	0.000
Q67.2 Dolichocephaly	0.004	0.996	0.000
Q67.1 Compression facies	0.004	0.996	0.000
Q67.0 Facial asymmetry	0.004	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.004	0.996	0.000
Q78.0 Osteogenesis imperfecta	0.004	0.996	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.004	0.996	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.004	0.996	0.000
Q74.3 Arthrogryposis multiplex congenita	0.004	0.996	0.000
Q39 Congenital malformations of oesophagus	0.004	0.996	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
Q39.4 Oesophageal web	0.004	0.996	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.003	0.996	0.000
Q78.8 Other specified osteochondrodysplasias	0.003	0.996	0.000
Q78.6 Multiple congenital exostoses	0.003	0.996	0.000
Q78.5 Metaphyseal dysplasia	0.003	0.996	0.000
Q78.4 Enchondromatosis	0.003	0.996	0.000
Q78.3 Progressive diaphyseal dysplasia	0.003	0.996	0.000
Q78.2 Osteopetrosis	0.003	0.996	0.000
Q78.1 Polyostotic fibrous dysplasia	0.003	0.996	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.996	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.996	0.000
H53-H54 Visual disturbances and blindness	0.000	0.996	0.004
M65.84 Other synovitis and tenosynovitis (Hand)	0.004	0.996	0.000
Z57.2 Occupational exposure to dust	0.000	0.996	0.004
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.996	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.996	0.000
Q68.3 Congenital bowing of femur	0.003	0.996	0.000
Q68.2 Congenital deformity of knee	0.003	0.996	0.000
Q68.1 Congenital deformity of hand	0.003	0.996	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.996	0.000
Q69.9 Polydactyly, unspecified	0.003	0.996	0.000
Q69.2 Accessory toe(s)	0.003	0.996	0.000
Q69.1 Accessory thumb(s)	0.003	0.996	0.000
Q69.0 Accessory finger(s)	0.003	0.996	0.000
Q70.9 Syndactyly, unspecified	0.003	0.996	0.000
Q70.4 Polysyndactyly	0.003	0.996	0.000
Q70.3 Webbed toes	0.003	0.996	0.000
Q70.2 Fused toes	0.003	0.996	0.000
Q70.1 Webbed fingers	0.003	0.996	0.000
Q70.0 Fused fingers	0.003	0.996	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.003	0.996	0.000
Q71.8 Other reduction defects of upper limb(s)	0.003	0.996	0.000
Q71.6 Lobster-claw hand	0.003	0.996	0.000
Q71.5 Longitudinal reduction defect of ulna	0.003	0.996	0.000
Q71.4 Longitudinal reduction defect of radius	0.003	0.996	0.000
Q71.3 Congenital absence of hand and finger(s)	0.003	0.996	0.000
Q71.2 Congenital absence of both forearm and hand	0.003	0.996	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.003	0.996	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.003	0.996	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.003	0.996	0.000
Q72.8 Other reduction defects of lower limb(s)	0.003	0.996	0.000
Q72.7 Split foot	0.003	0.996	0.000
Q72.6 Longitudinal reduction defect of fibula	0.003	0.996	0.000
Q72.5 Longitudinal reduction defect of tibia	0.003	0.996	0.000
Q72.4 Longitudinal reduction defect of femur	0.003	0.996	0.000
Q72.3 Congenital absence of foot and toe(s)	0.003	0.996	0.000
Q72.2 Congenital absence of both lower leg and foot	0.003	0.996	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.003	0.996	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.003	0.996	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.003	0.996	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.003	0.996	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.003	0.996	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.003	0.996	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.003	0.996	0.000
Q75.5 Oculomandibular dysostosis	0.003	0.996	0.000
Q75.4 Mandibulofacial dysostosis	0.003	0.996	0.000
Q75.3 Macrocephaly	0.003	0.996	0.000
Q75.2 Hypertelorism	0.003	0.996	0.000
Q75.1 Craniofacial dysostosis	0.003	0.996	0.000
Q75.0 Craniosynostosis	0.003	0.996	0.000
Q76.0 Spina bifida occulta	0.003	0.996	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.003	0.996	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.996	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.003	0.996	0.000
Q77.6 Chondroectodermal dysplasia	0.003	0.996	0.000
Q77.5 Diastrophic dysplasia	0.003	0.996	0.000
Q77.4 Achondroplasia	0.003	0.996	0.000
Q77.3 Chondrodysplasia punctata	0.003	0.996	0.000
Q77.2 Short rib syndrome	0.003	0.996	0.000
Q77.1 Thanatophoric short stature	0.003	0.996	0.000
Q77.0 Achondrogenesis	0.003	0.996	0.000
R27.0 Ataxia, unspecified	0.004	0.996	0.000
E04.9 Non-toxic goitre, unspecified	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.996	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
S82.3 Fracture of lower end of tibia	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
S02.50 Fracture of tooth (closed)	0.000	0.997	0.003
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
Q05 Spina bifida	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q40.2 Other specified congenital malformations of stomach	0.003	0.997	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.003	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.003	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.003	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.003	0.997	0.000
Q51.4 Unicornate uterus	0.003	0.997	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.003	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.003	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
M65.8 Other synovitis and tenosynovitis	0.003	0.997	0.000
Q44.6 Cystic disease of liver	0.003	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.003	0.997	0.000
D05.1 Intraductal carcinoma in situ	0.003	0.997	0.000
Q39.8 Other congenital malformations of oesophagus	0.003	0.997	0.000
Q39.5 Congenital dilatation of oesophagus	0.003	0.997	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.003	0.997	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.003	0.997	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.003	0.997	0.000
Q39.0 Atresia of oesophagus without fistula	0.003	0.997	0.000
Q55 Other congenital malformations of male genital organs	0.003	0.997	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.003	0.997	0.000
S82.1 Fracture of upper end of tibia	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
D37.4 Colon	0.003	0.997	0.000
Z29.0 Isolation	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q05.9 Spina bifida, unspecified	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.003	0.997	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
Q39.6 Diverticulum of oesophagus	0.003	0.997	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.003	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.003	0.997	0.000
Q79.4 Prune belly syndrome	0.003	0.997	0.000
Q79.3 Gastroschisis	0.003	0.997	0.000
Q79.2 Exomphalos	0.003	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.003	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.997	0.000
Q44.5 Other congenital malformations of bile ducts	0.003	0.997	0.000
O36 Maternal care for other known or suspected foetal problems	0.000	0.997	0.003
M46.4 Discitis, unspecified	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
S82.31 Fracture of lower end of tibia (open)	0.003	0.997	0.000
O36.9 Maternal care for foetal problem, unspecified	0.000	0.997	0.003
Z90.0 Acquired absence of part of head and neck	0.000	0.997	0.003
Q05.4 Unspecified spina bifida with hydrocephalus	0.003	0.997	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.003	0.997	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.997	0.003
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
Q40.1 Congenital hiatus hernia	0.003	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.003	0.997	0.000
Z43.2 Attention to ileostomy	0.003	0.997	0.000
M46 Other inflammatory spondylopathies	0.003	0.997	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.003	0.997	0.000
Q45.8 Other specified congenital malformations of digestive system	0.003	0.997	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.003	0.997	0.000
Q03 Congenital hydrocephalus	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
Q44.7 Other congenital malformations of liver	0.003	0.997	0.000
Q44.4 Choledochal cyst	0.003	0.997	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.003	0.997	0.000
Q44.2 Atresia of bile ducts	0.003	0.997	0.000
Q44.1 Other congenital malformations of gallbladder	0.003	0.997	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.003	0.997	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.003	0.997	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.003	0.997	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.003	0.997	0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.003	0.997	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.997	0.000
T50.7 Analeptics and opioid receptor antagonists	0.003	0.997	0.000
T50.5 Appetite depressants	0.003	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
Q53 Undescended testicle	0.003	0.997	0.000
Q54 Hypospadias	0.002	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.997	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.997	0.003
Q05.8 Sacral spina bifida without hydrocephalus	0.002	0.997	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.002	0.997	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.002	0.997	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.002	0.997	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.002	0.997	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.002	0.997	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.002	0.997	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.002	0.997	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.002	0.997	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.002	0.997	0.000
Q98.7 Male with sex chromosome mosaicism	0.002	0.997	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.002	0.997	0.000
Q98.5 Karyotype 47,XYY	0.002	0.997	0.000
Q98.3 Other male with 46,XX karyotype	0.002	0.997	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.002	0.997	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.002	0.997	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.002	0.997	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.002	0.997	0.000
E04.2 Non-toxic multinodular goitre	0.003	0.997	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.997	0.000
Q90 Down's syndrome	0.002	0.997	0.000
M45-M49 Spondylopathies	0.003	0.997	0.000
S82.11 Fracture of upper end of tibia (open)	0.002	0.997	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.997	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.997	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.997	0.000
Q45.1 Annular pancreas	0.002	0.997	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.997	0.000
Q54.0 Hypospadias, balanic	0.002	0.997	0.000
Q55.6 Other congenital malformations of penis	0.002	0.997	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.002	0.997	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.002	0.997	0.000
G63.2 Diabetic polyneuropathy	0.003	0.997	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.002	0.997	0.000
Q06.4 Hydromyelia	0.002	0.997	0.000
Q06.3 Other congenital cauda equina malformations	0.002	0.997	0.000
Q06.2 Diastematomyelia	0.002	0.997	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.002	0.997	0.000
Q06.0 Amyelia	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations