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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs188448092
log Bayes Factor = 23.8385
Chromosome 13   position 24,544,751  (GRCh37) Explore rs188448092 on Ensembl!
Variant rs188448092 is part of Cluster X0152

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.997 0.003 0.000
Z92 Personal history of medical treatment
0.997 0.003 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
Chapter II Neoplasms
0.996 0.004 0.000
N17-N19 Renal failure
0.995 0.005 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.993 0.007 0.000
R00 Abnormalities of heart beat
0.992 0.008 0.000
Chapter IX Diseases of the circulatory system
0.987 0.013 0.000
N18 Chronic renal failure
0.987 0.013 0.000
B95-B98 Bacterial, viral and other infectious agents
0.986 0.014 0.000
Z51 Other medical care
0.985 0.015 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.984 0.016 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.982 0.018 0.000
R00.1 Bradycardia, unspecified
0.980 0.020 0.000
F30-F39 Mood [affective] disorders
0.980 0.020 0.000
M50-M54 Other dorsopathies
0.977 0.023 0.000
D70 Agranulocytosis
0.974 0.026 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.974 0.026 0.000
C79 Secondary malignant neoplasm of other sites
0.973 0.027 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.972 0.028 0.000
Chapter XX External causes of morbidity and mortality
0.969 0.031 0.000
N18.9 Chronic renal failure, unspecified
0.968 0.032 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.964 0.036 0.000
I95 Hypotension
0.961 0.039 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.957 0.043 0.000
I95.9 Hypotension, unspecified
0.957 0.043 0.000
Z53.9 Procedure not carried out, unspecified reason
0.956 0.044 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.955 0.045 0.000
A30-A49 Other bacterial diseases
0.951 0.049 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.947 0.053 0.000
R42 Dizziness and giddiness
0.947 0.053 0.000
Z92.3 Personal history of irradiation
0.945 0.055 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.944 0.056 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.943 0.057 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.942 0.058 0.000
M45-M49 Spondylopathies
0.935 0.065 0.000
M54 Dorsalgia
0.934 0.066 0.000
I30-I52 Other forms of heart disease
0.929 0.071 0.000
Z51.3 Blood transfusion without reported diagnosis
0.928 0.072 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.926 0.074 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.925 0.075 0.000
Chapter X Diseases of the respiratory system
0.923 0.077 0.000
Z98 Other postsurgical states
0.921 0.079 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.919 0.081 0.000
N17 Acute renal failure
0.919 0.081 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.917 0.083 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.917 0.083 0.000
Z51.5 Palliative care
0.917 0.083 0.000
Z50 Care involving use of rehabilitation procedures
0.914 0.086 0.000
F10.2 Dependence syndrome
0.914 0.086 0.000
A41 Other septicaemia
0.912 0.088 0.000
F32 Depressive episode
0.912 0.088 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.912 0.088 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.911 0.089 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.906 0.094 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.906 0.094 0.000
M20-M25 Other joint disorders
0.904 0.096 0.000
Z94 Transplanted organ and tissue status
0.902 0.098 0.000
C15-C26 Malignant neoplasms of digestive organs
0.901 0.099 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.901 0.099 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.900 0.100 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.897 0.103 0.000
C78.7 Secondary malignant neoplasm of liver
0.895 0.105 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.894 0.106 0.000
Z53.8 Procedure not carried out for other reasons
0.892 0.108 0.000
B15-B19 Viral hepatitis
0.889 0.111 0.000
Z13 Special screening examination for other diseases and disorders
0.888 0.112 0.000
Z43 Attention to artificial openings
0.887 0.113 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.886 0.114 0.000
A41.9 Septicaemia, unspecified
0.885 0.115 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.883 0.117 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.883 0.117 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.878 0.122 0.000
O00-O08 Pregnancy with abortive outcome
0.878 0.122 0.000
C78.0 Secondary malignant neoplasm of lung
0.876 0.124 0.000
F10.0 Acute intoxication
0.873 0.127 0.000
F33 Recurrent depressive disorder
0.872 0.128 0.000
Chapter VIII Diseases of the ear and mastoid process
0.871 0.129 0.000
A00-A09 Intestinal infectious diseases
0.870 0.130 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.865 0.135 0.000
N17.9 Acute renal failure, unspecified
0.864 0.136 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.862 0.138 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.860 0.140 0.000
M25 Other joint disorders, not elsewhere classified
0.860 0.140 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.859 0.141 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.857 0.143 0.000
M50 Cervical disk disorders
0.855 0.145 0.000
Z97 Presence of other devices
0.854 0.146 0.000
F31 Bipolar affective disorder
0.854 0.146 0.000
Z90.5 Acquired absence of kidney
0.851 0.149 0.000
D80-D89 Certain disorders involving the immune mechanism
0.849 0.151 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.848 0.152 0.000
M47 Spondylosis
0.847 0.153 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.847 0.153 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.843 0.157 0.000
J09-J18 Influenza and pneumonia
0.842 0.158 0.000
C34 Malignant neoplasm of bronchus and lung
0.842 0.158 0.000
N89 Other noninflammatory disorders of vagina
0.839 0.161 0.000
R05 Cough
0.837 0.163 0.000
N81 Female genital prolapse
0.833 0.167 0.000
Z51.0 Radiotherapy session
0.832 0.168 0.000
T81 Complications of procedures, not elsewhere classified
0.831 0.169 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.830 0.170 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.829 0.171 0.000
R40 Somnolence, stupor and coma
0.827 0.173 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.827 0.173 0.000
I35 Nonrheumatic aortic valve disorders
0.824 0.176 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.820 0.180 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.820 0.180 0.000
D60-D64 Aplastic and other anaemias
0.816 0.184 0.000
O03 Spontaneous abortion
0.815 0.185 0.000
Z13.9 Special screening examination, unspecified
0.814 0.186 0.000
O80-O84 Delivery
0.814 0.186 0.000
Z86 Personal history of certain other diseases
0.814 0.186 0.000
Z99.2 Dependence on renal dialysis
0.813 0.187 0.000
M54.5 Low back pain
0.813 0.187 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.811 0.189 0.000
B18 Chronic viral hepatitis
0.809 0.191 0.000
M40-M43 Deforming dorsopathies
0.809 0.191 0.000
Z43.2 Attention to ileostomy
0.806 0.194 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.804 0.196 0.000
Z35 Supervision of high-risk pregnancy
0.804 0.196 0.000
C20 Malignant neoplasm of rectum
0.803 0.197 0.000
Z36 Antenatal screening
0.802 0.198 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.801 0.199 0.000
C18 Malignant neoplasm of colon
0.799 0.201 0.000
N18.5 Chronic kidney disease, stage 5
0.796 0.204 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.796 0.204 0.000
Z88.6 Personal history of allergy to analgesic agent
0.794 0.206 0.000
I44 Atrioventricular and left bundle-branch block
0.794 0.206 0.000
M54.3 Sciatica
0.794 0.206 0.000
J90-J94 Other diseases of pleura
0.793 0.207 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.792 0.208 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.791 0.209 0.000
M91-M94 Chondropathies
0.791 0.209 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.791 0.209 0.000
N00-N08 Glomerular diseases
0.791 0.209 0.000
N18.3 Chronic kidney disease, stage 3
0.790 0.210 0.000
Z45 Adjustment and management of implanted device
0.789 0.211 0.000
N81.1 Cystocele
0.785 0.215 0.000
Z98.0 Intestinal bypass and anastomosis status
0.784 0.216 0.000
I38 Endocarditis, valve unspecified
0.783 0.217 0.000
N30-N39 Other diseases of urinary system
0.783 0.217 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.782 0.218 0.000
W20-W49 Exposure to inanimate mechanical forces
0.782 0.218 0.000
J30-J39 Other diseases of upper respiratory tract
0.780 0.220 0.000
I42 Cardiomyopathy
0.780 0.220 0.000
Chapter XXII Codes for special purposes
0.780 0.220 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.779 0.220 0.000
H80-H83 Diseases of inner ear
0.776 0.224 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.776 0.224 0.000
Z50.1 Other physical therapy
0.776 0.224 0.000
C34.1 Upper lobe, bronchus or lung
0.776 0.224 0.000
N18.4 Chronic kidney disease, stage 4
0.775 0.225 0.000
N99-N99 Other disorders of the genitourinary system
0.775 0.225 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.774 0.226 0.000
Z94.8 Other transplanted organ and tissue status
0.774 0.226 0.000
M54.1 Radiculopathy
0.772 0.228 0.000
N81.6 Rectocele
0.771 0.229 0.000
F60-F69 Disorders of adult personality and behaviour
0.771 0.229 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.770 0.230 0.000
R00.0 Tachycardia, unspecified
0.770 0.230 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.770 0.230 0.000
R45 Symptoms and signs involving emotional state
0.766 0.234 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.765 0.235 0.000
F33.9 Recurrent depressive disorder, unspecified
0.765 0.235 0.000
R02 Gangrene, not elsewhere classified
0.764 0.236 0.000
Z89 Acquired absence of limb
0.764 0.236 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.764 0.236 0.000
B35-B49 Mycoses
0.763 0.237 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.763 0.237 0.000
M22 Disorders of patella
0.763 0.237 0.000
F32.9 Depressive episode, unspecified
0.762 0.238 0.000
Z94.0 Kidney transplant status
0.761 0.239 0.000
M51 Other intervertebral disk disorders
0.761 0.239 0.000
I50 Heart failure
0.760 0.240 0.000
R79 Other abnormal findings of blood chemistry
0.760 0.240 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.759 0.241 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.758 0.241 0.000
M23 Internal derangement of knee
0.757 0.243 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.756 0.244 0.000
M70-M79 Other soft tissue disorders
0.754 0.246 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.753 0.247 0.000
B18.2 Chronic viral hepatitis C
0.753 0.247 0.000
N18.0 End-stage renal disease
0.751 0.249 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.751 0.249 0.000
I36 Nonrheumatic tricuspid valve disorders
0.751 0.249 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.750 0.249 0.000
Z49 Care involving dialysis
0.750 0.250 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.750 0.250 0.000
V20-V29 Motorcycle rider injured in transport accident
0.749 0.251 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.746 0.254 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.746 0.254 0.000
R94 Abnormal results of function studies
0.745 0.255 0.000
M54.2 Cervicalgia
0.744 0.256 0.000
C80 Malignant neoplasm without specification of site
0.744 0.256 0.000
R40.0 Somnolence
0.744 0.256 0.000
J18 Pneumonia, organism unspecified
0.743 0.257 0.000
Z41 Procedures for purposes other than remedying health state
0.743 0.257 0.000
M65-M68 Disorders of synovium and tendon
0.743 0.257 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.743 0.257 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.743 0.257 0.000
D61 Other aplastic anaemias
0.742 0.258 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.742 0.258 0.000
Z40 Prophylactic surgery
0.741 0.259 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.741 0.259 0.000
D75 Other diseases of blood and blood-forming organs
0.741 0.259 0.000
Z99.3 Dependence on wheelchair
0.741 0.259 0.000
Z80 Family history of malignant neoplasm
0.740 0.260 0.000
O03.9 Complete or unspecified, without complication
0.739 0.261 0.000
N40-N51 Diseases of male genital organs
0.739 0.261 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.738 0.262 0.000
Chapter VI Diseases of the nervous system
0.738 0.262 0.000
R50-R69 General symptoms and signs
0.737 0.263 0.000
M48 Other spondylopathies
0.736 0.264 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.736 0.264 0.000
C81 Hodgkin's disease
0.736 0.264 0.000
M25.5 Pain in joint
0.736 0.264 0.000
C18.7 Sigmoid colon
0.735 0.265 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.733 0.267 0.000
M47.8 Other spondylosis
0.733 0.267 0.000
Z99.1 Dependence on respirator
0.732 0.268 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.732 0.268 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.731 0.269 0.000
Z50.2 Alcohol rehabilitation
0.731 0.269 0.000
Chapter XI Diseases of the digestive system
0.730 0.270 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.729 0.271 0.000
R04 Haemorrhage from respiratory passages
0.729 0.271 0.000
T66-T78 Other and unspecified effects of external causes
0.729 0.271 0.000
Z45.2 Adjustment and management of vascular access device
0.728 0.272 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.727 0.273 0.000
F31.9 Bipolar affective disorder, unspecified
0.726 0.274 0.000
R47-R49 Symptoms and signs involving speech and voice
0.726 0.274 0.000
N75 Diseases of Bartholin's gland
0.725 0.275 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.725 0.275 0.000
Z98.1 Arthrodesis status
0.724 0.276 0.000
M46 Other inflammatory spondylopathies
0.723 0.277 0.000
R94.5 Abnormal results of liver function studies
0.722 0.278 0.000
I05-I09 Chronic rheumatic heart diseases
0.721 0.279 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.721 0.279 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.721 0.279 0.000
I31 Other diseases of pericardium
0.720 0.280 0.000
D72 Other disorders of white blood cells
0.720 0.280 0.000
I60-I69 Cerebrovascular diseases
0.720 0.280 0.000
M54.6 Pain in thoracic spine
0.719 0.281 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.719 0.281 0.000
J93 Pneumothorax
0.719 0.281 0.000
M25.4 Effusion of joint
0.719 0.281 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.718 0.282 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.718 0.282 0.000
Z90.3 Acquired absence of part of stomach
0.717 0.283 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
Z54 Convalescence
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.716 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.283 0.000
B65-B83 Helminthiases
0.716 0.283 0.000
B50-B64 Protozoal diseases
0.716 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.283 0.000
A75-A79 Rickettsioses
0.716 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.283 0.000
A65-A69 Other spirochaetal diseases
0.716 0.283 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.716 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.283 0.000
A15-A19 Tuberculosis
0.716 0.283 0.000
Z52 Donors of organs and tissues
0.716 0.284 0.000
A49 Bacterial infection of unspecified site
0.716 0.284 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.716 0.284 0.000
Z13.1 Special screening examination for diabetes mellitus
0.715 0.285 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F80-F89 Disorders of psychological development
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
M86-M90 Other osteopathies
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
Z92.9 Personal history of medical treatment, unspecified
0.715 0.285 0.000
Z92.8 Personal history of other medical treatment
0.715 0.285 0.000
Z92.5 Personal history of rehabilitation measures
0.715 0.285 0.000
D55-D59 Haemolytic anaemias
0.714 0.285 0.000
M25.8 Other specified joint disorders
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
F32.1 Moderate depressive episode
0.714 0.286 0.000
N19 Unspecified renal failure
0.714 0.286 0.000
S80-S89 Injuries to the knee and lower leg
0.714 0.286 0.000
Z34 Supervision of normal pregnancy
0.713 0.287 0.000
I10-I15 Hypertensive diseases
0.713 0.287 0.000
Z51.8 Other specified medical care
0.713 0.287 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.712 0.288 0.000
M45 Ankylosing spondylitis
0.712 0.288 0.000
Z83 Family history of other specific disorders
0.711 0.288 0.000
O16 Unspecified maternal hypertension
0.711 0.289 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.711 0.289 0.000
O02 Other abnormal products of conception
0.711 0.289 0.000
M54.57 Low back pain (Lumbosacral region)
0.711 0.289 0.000
E65-E68 Obesity and other hyperalimentation
0.711 0.289 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.711 0.289 0.000
N90.4 Leukoplakia of vulva
0.710 0.290 0.000
D69 Purpura and other haemorrhagic conditions
0.709 0.291 0.000
I95.2 Hypotension due to drugs
0.709 0.291 0.000
M53 Other dorsopathies, not elsewhere classified
0.708 0.291 0.000
R80 Isolated proteinuria
0.708 0.292 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.708 0.292 0.000
N82 Fistulae involving female genital tract
0.708 0.292 0.000
I00-I02 Acute rheumatic fever
0.708 0.292 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.708 0.292 0.000
N18.8 Other chronic renal failure
0.707 0.293 0.000
N18.2 Chronic kidney disease, stage 2
0.707 0.293 0.000
N18.1 Chronic kidney disease, stage 1
0.707 0.293 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.707 0.293 0.000
M47.9 Spondylosis, unspecified
0.706 0.293 0.000
Z51.9 Medical care, unspecified
0.706 0.294 0.000
Z51.6 Desensitisation to allergens
0.706 0.294 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.705 0.294 0.000
D74 Methaemoglobinaemia
0.705 0.294 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.705 0.294 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.705 0.294 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.705 0.295 0.000
Z97.4 Presence of external hearing-aid
0.705 0.295 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.705 0.295 0.000
X60-X84 Intentional self-harm
0.704 0.296 0.000
Y40 Systemic antibiotics
0.704 0.296 0.000
Z47 Other orthopaedic follow-up care
0.704 0.296 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.704 0.296 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.704 0.296 0.000
Z88.5 Personal history of allergy to narcotic agent
0.703 0.297 0.000
F38 Other mood [affective] disorders
0.703 0.297 0.000
F34 Persistent mood [affective] disorders
0.703 0.297 0.000
F30 Manic episode
0.703 0.297 0.000
F39 Unspecified mood [affective] disorder
0.703 0.297 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.702 0.298 0.000
Z92.0 Personal history of contraception
0.701 0.299 0.000
Y84.0 Cardiac catheterisation
0.701 0.299 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.701 0.299 0.000
I44.1 Atrioventricular block, second degree
0.701 0.299 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.700 0.300 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.700 0.300 0.000
I33 Acute and subacute endocarditis
0.700 0.300 0.000
C34.0 Main bronchus
0.699 0.300 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.699 0.301 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.699 0.301 0.000
F99-F99 Unspecified mental disorder
0.699 0.301 0.000
S20-S29 Injuries to the thorax
0.699 0.301 0.000
R03.1 Nonspecific low blood-pressure reading
0.698 0.302 0.000
R46 Symptoms and signs involving appearance and behaviour
0.698 0.302 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.698 0.302 0.000
R43 Disturbances of smell and taste
0.698 0.302 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.698 0.302 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.698 0.302 0.000
C79.6 Secondary malignant neoplasm of ovary
0.698 0.302 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.698 0.302 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.698 0.302 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.698 0.302 0.000
O80 Single spontaneous delivery
0.697 0.303 0.000
J18.1 Lobar pneumonia, unspecified
0.697 0.303 0.000
I30 Acute pericarditis
0.697 0.303 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.697 0.303 0.000
I99 Other and unspecified disorders of circulatory system
0.697 0.303 0.000
Z90.1 Acquired absence of breast(s)
0.697 0.303 0.000
N86 Erosion and ectropion of cervix uteri
0.697 0.303 0.000
Y84.8 Other medical procedures
0.696 0.304 0.000
H90-H95 Other disorders of ear
0.696 0.304 0.000
K70-K77 Diseases of liver
0.696 0.304 0.000
Z39 Postpartum care and examination
0.695 0.305 0.000
K55-K64 Other diseases of intestines
0.695 0.305 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.695 0.305 0.000
Y35-Y36 Legal intervention and operations of war
0.695 0.305 0.000
Y10-Y34 Event of undetermined intent
0.695 0.305 0.000
Y00-Y09 Assault
0.695 0.305 0.000
X85-X99 Assault
0.695 0.305 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.695 0.305 0.000
X50-X57 Overexertion, travel and privation
0.695 0.305 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.695 0.305 0.000
X30-X39 Exposure to forces of nature
0.695 0.305 0.000
X20-X29 Contact with venomous animals and plants
0.695 0.305 0.000
X10-X19 Contact with heat and hot substances
0.695 0.305 0.000
X00-X09 Exposure to smoke, fire and flames
0.695 0.305 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.695 0.305 0.000
W75-W84 Other accidental threats to breathing
0.695 0.305 0.000
W65-W74 Accidental drowning and submersion
0.695 0.305 0.000
W50-W64 Exposure to animate mechanical forces
0.695 0.305 0.000
V98-V99 Other and unspecified transport accidents
0.695 0.305 0.000
V95-V97 Air and space transport accidents
0.695 0.305 0.000
V90-V94 Water transport accidents
0.695 0.305 0.000
V80-V89 Other land transport accidents
0.695 0.305 0.000
V70-V79 Bus occupant injured in transport accident
0.695 0.305 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.695 0.305 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.695 0.305 0.000
V40-V49 Car occupant injured in transport accident
0.695 0.305 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.695 0.305 0.000
V01-V09 Pedestrian injured in transport accident
0.695 0.305 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.694 0.306 0.000
D68 Other coagulation defects
0.693 0.307 0.000
R30-R39 Symptoms and signs involving the urinary system
0.693 0.307 0.000
Z50.8 Care involving use of rehabilitation procedures
0.692 0.308 0.000
Z86.0 Personal history of other neoplasms
0.692 0.308 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.692 0.308 0.000
N81.4 Uterovaginal prolapse, unspecified
0.691 0.309 0.000
M50.0 Cervical disk disorder with myelopathy
0.691 0.309 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.691 0.309 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.691 0.309 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.691 0.309 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.691 0.309 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.691 0.309 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.691 0.309 0.000
C51-C58 Malignant neoplasms of female genital organs
0.691 0.309 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.690 0.310 0.000
D61.9 Aplastic anaemia, unspecified
0.690 0.310 0.000
R73 Elevated blood glucose level
0.689 0.310 0.000
E66 Obesity
0.689 0.311 0.000
I95.8 Other hypotension
0.689 0.311 0.000
I95.0 Idiopathic hypotension
0.689 0.311 0.000
S50-S59 Injuries to the elbow and forearm
0.687 0.313 0.000
M24 Other specific joint derangements
0.687 0.313 0.000
B25-B34 Other viral diseases
0.687 0.313 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.686 0.314 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.686 0.314 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.686 0.314 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.686 0.314 0.000
Z98.8 Other specified postsurgical states
0.686 0.314 0.000
C32 Malignant neoplasm of larynx
0.685 0.315 0.000
M50.3 Other cervical disk degeneration
0.685 0.315 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.685 0.315 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.685 0.315 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.685 0.315 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.685 0.315 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.685 0.315 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.685 0.315 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.685 0.315 0.000
F11 Mental and behavioural disorders due to use of opioids
0.685 0.315 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.685 0.315 0.000
N90.7 Vulvar cyst
0.684 0.316 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.684 0.316 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.682 0.318 0.000
A48 Other bacterial diseases, not elsewhere classified
0.682 0.318 0.000
A44 Bartonellosis
0.682 0.318 0.000
A43 Nocardiosis
0.682 0.318 0.000
A42 Actinomycosis
0.682 0.318 0.000
A40 Streptococcal septicaemia
0.682 0.318 0.000
A39 Meningococcal infection
0.682 0.318 0.000
A37 Whooping cough
0.682 0.318 0.000
A36 Diphtheria
0.682 0.318 0.000
A32 Listeriosis
0.682 0.318 0.000
A31 Infection due to other mycobacteria
0.682 0.318 0.000
A30 Leprosy [Hansen's disease]
0.682 0.318 0.000
A46 Erysipelas
0.682 0.318 0.000
A38 Scarlet fever
0.682 0.318 0.000
A35 Other tetanus
0.682 0.318 0.000
A34 Obstetrical tetanus
0.682 0.318 0.000
A33 Tetanus neonatorum
0.682 0.318 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.682 0.318 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.681 0.319 0.000
N89.6 Tight hymenal ring
0.681 0.319 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.681 0.319 0.000
J14 Pneumonia due to Haemophilus influenzae
0.681 0.319 0.000
C78.2 Secondary malignant neoplasm of pleura
0.680 0.320 0.000
Z42 Follow-up care involving plastic surgery
0.680 0.320 0.000
Z31 Procreative management
0.680 0.320 0.000
N25-N29 Other disorders of kidney and ureter
0.680 0.320 0.000
A02 Other Salmonella infections
0.680 0.320 0.000
D73 Diseases of spleen
0.679 0.320 0.000
C60-C63 Malignant neoplasms of male genital organs
0.679 0.321 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.679 0.321 0.000
O03.4 Incomplete, without complication
0.678 0.322 0.000
C79.2 Secondary malignant neoplasm of skin
0.678 0.322 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.677 0.322 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.677 0.323 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.677 0.323 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.677 0.323 0.000
Z91.7 Personal history of female genital mutilation
0.677 0.323 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.677 0.323 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.677 0.323 0.000
Z91.2 Personal history of poor personal hygiene
0.677 0.323 0.000
O85-O92 Complications predominantly related to the puerperium
0.676 0.324 0.000
F10.9 Unspecified mental and behavioural disorder
0.675 0.325 0.000
F10.8 Other mental and behavioural disorders
0.675 0.325 0.000
F10.7 Residual and late-onset psychotic disorder
0.675 0.325 0.000
F10.6 Amnesic syndrome
0.675 0.325 0.000
F10.5 Psychotic disorder
0.675 0.325 0.000
F10.4 Withdrawal state with delirium
0.675 0.325 0.000
Z46 Fitting and adjustment of other devices
0.675 0.325 0.000
Z30 Contraceptive management
0.675 0.325 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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