TreeWAS – Variant ID: rs1949733

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I84.1 Internal haemorrhoids with other complications	0.000	0.894	0.106
G25.0 Essential tremor	0.019	0.981	0.000
H40.9 Glaucoma, unspecified	0.000	0.982	0.018
H35.4 Peripheral retinal degeneration	0.000	0.985	0.015
G25 Other extrapyramidal and movement disorders	0.011	0.989	0.000
G25.2 Other specified forms of tremor	0.009	0.991	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.008	0.992	0.000
G25.5 Other chorea	0.008	0.992	0.000
G25.3 Myoclonus	0.008	0.992	0.000
G25.1 Drug-induced tremor	0.008	0.992	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.008	0.992	0.000
G25.4 Drug-induced chorea	0.008	0.992	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.993	0.007
M89.9 Disorder of bone, unspecified	0.000	0.993	0.007
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.994	0.006
N90.7 Vulvar cyst	0.006	0.994	0.000
H92.0 Otalgia	0.000	0.994	0.006
H93.1 Tinnitus	0.000	0.994	0.006
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.994	0.006
Q89.2 Congenital malformations of other endocrine glands	0.000	0.994	0.005
M89.98 Disorder of bone, unspecified (Other)	0.000	0.995	0.005
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.995	0.005
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.995	0.005
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.995	0.005
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.995	0.005
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.995	0.005
M89 Other disorders of bone	0.000	0.995	0.005
M89.8 Other specified disorders of bone	0.000	0.995	0.005
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.995	0.005
G20-G26 Extrapyramidal and movement disorders	0.005	0.995	0.000
H80.9 Otosclerosis, unspecified	0.000	0.995	0.005
G24 Dystonia	0.004	0.996	0.000
G24.5 Blepharospasm	0.004	0.996	0.000
M89.5 Osteolysis	0.000	0.996	0.004
G59.0 Diabetic mononeuropathy	0.004	0.996	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.996	0.004
T90.4 Sequelae of injury of eye and orbit	0.000	0.996	0.004
M89.55 Osteolysis (Pelvic region and thigh)	0.000	0.996	0.004
M89.81 Other specified disorders of bone (Shoulder region)	0.000	0.996	0.004
Q51 Congenital malformations of uterus and cervix	0.004	0.996	0.000
H93 Other disorders of ear, not elsewhere classified	0.000	0.996	0.004
Q51.8 Other congenital malformations of uterus and cervix	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
Q55 Other congenital malformations of male genital organs	0.004	0.996	0.000
H92 Otalgia and effusion of ear	0.000	0.996	0.004
Q51.3 Bicornate uterus	0.004	0.996	0.000
Q05.9 Spina bifida, unspecified	0.004	0.996	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.000	0.996	0.004
Q55.2 Other congenital malformations of testis and scrotum	0.004	0.996	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.996	0.004
M89.89 Other specified disorders of bone (Site unspecified)	0.000	0.996	0.004
M89.83 Other specified disorders of bone (Forearm)	0.000	0.996	0.004
M89.6 Osteopathy after poliomyelitis	0.000	0.996	0.004
M89.2 Other disorders of bone development and growth	0.000	0.996	0.004
M89.1 Epiphyseal arrest	0.000	0.996	0.004
G24.9 Dystonia, unspecified	0.004	0.996	0.000
Q53 Undescended testicle	0.004	0.996	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.004	0.996	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.996	0.004
G24.1 Idiopathic familial dystonia	0.004	0.996	0.000
D07.5 Prostate	0.004	0.996	0.000
K65.0 Acute peritonitis	0.004	0.996	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.000	0.996	0.004
M89.80 Other specified disorders of bone (Multiple sites)	0.000	0.996	0.004
R27.0 Ataxia, unspecified	0.004	0.996	0.000
M89.3 Hypertrophy of bone	0.000	0.996	0.004
G21 Secondary Parkinsonism	0.003	0.996	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.003	0.996	0.000
G22 Parkinsonism in diseases classified elsewhere	0.003	0.996	0.000
D07.1 Vulva	0.004	0.996	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.996	0.004
G23 Other degenerative diseases of basal ganglia	0.003	0.996	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.003	0.996	0.000
G24.4 Idiopathic orofacial dystonia	0.003	0.997	0.000
G24.2 Idiopathic nonfamilial dystonia	0.003	0.997	0.000
M89.59 Osteolysis (Site unspecified)	0.000	0.997	0.003
M89.58 Osteolysis (Other)	0.000	0.997	0.003
M89.57 Osteolysis (Ankle and foot)	0.000	0.997	0.003
M89.54 Osteolysis (Hand)	0.000	0.997	0.003
M89.53 Osteolysis (Forearm)	0.000	0.997	0.003
M89.52 Osteolysis (Upper arm)	0.000	0.997	0.003
M89.51 Osteolysis (Shoulder region)	0.000	0.997	0.003
M89.50 Osteolysis (Multiple sites)	0.000	0.997	0.003
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.997	0.003
H92.2 Otorrhagia	0.000	0.997	0.003
Q55.0 Absence and aplasia of testis	0.003	0.997	0.000
M89.84 Other specified disorders of bone (Hand)	0.000	0.997	0.003
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.003	0.997	0.000
G24.0 Drug-induced dystonia	0.003	0.997	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.003	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.003	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.003	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.003	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.003	0.997	0.000
Q53.9 Undescended testicle, unspecified	0.003	0.997	0.000
Q05 Spina bifida	0.003	0.997	0.000
K86.1 Other chronic pancreatitis	0.003	0.997	0.000
G24.3 Spasmodic torticollis	0.003	0.997	0.000
H93.0 Degenerative and vascular disorders of ear	0.000	0.997	0.003
M89.0 Algoneurodystrophy	0.000	0.997	0.003
Q51.2 Other doubling of uterus	0.003	0.997	0.000
M89.88 Other specified disorders of bone (Other)	0.000	0.997	0.003
H93.2 Other abnormal auditory perceptions	0.000	0.997	0.003
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.003	0.997	0.000
Z84.8 Family history of other specified conditions	0.000	0.997	0.003
M89.56 Osteolysis (Lower leg)	0.000	0.997	0.003
Q53.2 Undescended testicle, bilateral	0.003	0.997	0.000
Q55.6 Other congenital malformations of penis	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
H93.8 Other specified disorders of ear	0.000	0.997	0.003
Q51.4 Unicornate uterus	0.003	0.997	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.003	0.997	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.003	0.997	0.000
Q55.5 Congenital absence and aplasia of penis	0.003	0.997	0.000
Q55.3 Atresia of vas deferens	0.003	0.997	0.000
Q55.1 Hypoplasia of testis and scrotum	0.003	0.997	0.000
H93.3 Disorders of acoustic nerve	0.000	0.997	0.003
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.000	0.997	0.003
D07 Carcinoma in situ of other and unspecified genital organs	0.003	0.997	0.000
G24.8 Other dystonia	0.003	0.997	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.997	0.003
Q54 Hypospadias	0.003	0.997	0.000
Q50.5 Embryonic cyst of broad ligament	0.003	0.997	0.000
Q89 Other congenital malformations, not elsewhere classified	0.001	0.997	0.002
H90-H95 Other disorders of ear	0.000	0.997	0.003
H93.9 Disorder of ear, unspecified	0.000	0.997	0.003
K86.0 Alcohol-induced chronic pancreatitis	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.000	0.997	0.003
M89.48 Other hypertrophic osteoarthropathy (Other)	0.000	0.997	0.003
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.000	0.997	0.003
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.000	0.997	0.003
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.000	0.997	0.003
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.000	0.997	0.003
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.000	0.997	0.003
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.000	0.997	0.003
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.000	0.997	0.003
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.000	0.997	0.003
M89.18 Epiphyseal arrest (Other)	0.000	0.997	0.003
M89.17 Epiphyseal arrest (Ankle and foot)	0.000	0.997	0.003
M89.16 Epiphyseal arrest (Lower leg)	0.000	0.997	0.003
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.000	0.997	0.003
M89.14 Epiphyseal arrest (Hand)	0.000	0.997	0.003
M89.13 Epiphyseal arrest (Forearm)	0.000	0.997	0.003
M89.12 Epiphyseal arrest (Upper arm)	0.000	0.997	0.003
M89.11 Epiphyseal arrest (Shoulder region)	0.000	0.997	0.003
M89.10 Epiphyseal arrest (Multiple sites)	0.000	0.997	0.003
M89.29 Other disorders of bone development and growth (Site unspecified)	0.000	0.997	0.003
M89.28 Other disorders of bone development and growth (Other)	0.000	0.997	0.003
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.000	0.997	0.003
M89.26 Other disorders of bone development and growth (Lower leg)	0.000	0.997	0.003
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.000	0.997	0.003
M89.24 Other disorders of bone development and growth (Hand)	0.000	0.997	0.003
M89.23 Other disorders of bone development and growth (Forearm)	0.000	0.997	0.003
M89.22 Other disorders of bone development and growth (Upper arm)	0.000	0.997	0.003
M89.21 Other disorders of bone development and growth (Shoulder region)	0.000	0.997	0.003
M89.20 Other disorders of bone development and growth (Multiple sites)	0.000	0.997	0.003
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.000	0.997	0.003
M89.68 Osteopathy after poliomyelitis (Other)	0.000	0.997	0.003
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.000	0.997	0.003
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.000	0.997	0.003
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.000	0.997	0.003
M89.64 Osteopathy after poliomyelitis (Hand)	0.000	0.997	0.003
M89.63 Osteopathy after poliomyelitis (Forearm)	0.000	0.997	0.003
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.000	0.997	0.003
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.000	0.997	0.003
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.000	0.997	0.003
D07.4 Penis	0.003	0.997	0.000
K86.8 Other specified diseases of pancreas	0.003	0.997	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.997	0.000
Q53.0 Ectopic testis	0.003	0.997	0.000
G21.0 Malignant neuroleptic syndrome	0.003	0.997	0.000
K86 Other diseases of pancreas	0.003	0.997	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.003	0.997	0.000
M89.38 Hypertrophy of bone (Other)	0.000	0.997	0.003
Q53.1 Undescended testicle, unilateral	0.003	0.997	0.000
M89.03 Algoneurodystrophy (Forearm)	0.000	0.997	0.003
M89.39 Hypertrophy of bone (Site unspecified)	0.000	0.997	0.003
M89.36 Hypertrophy of bone (Lower leg)	0.000	0.997	0.003
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.000	0.997	0.003
M89.34 Hypertrophy of bone (Hand)	0.000	0.997	0.003
M89.33 Hypertrophy of bone (Forearm)	0.000	0.997	0.003
M89.32 Hypertrophy of bone (Upper arm)	0.000	0.997	0.003
M89.31 Hypertrophy of bone (Shoulder region)	0.000	0.997	0.003
M89.30 Hypertrophy of bone (Multiple sites)	0.000	0.997	0.003
M89.04 Algoneurodystrophy (Hand)	0.000	0.997	0.003
G21.8 Other secondary Parkinsonism	0.003	0.997	0.000
G21.4 Vascular parkinsonism	0.003	0.997	0.000
G21.3 Postencephalitic Parkinsonism	0.003	0.997	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.003	0.997	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.003	0.997	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.003	0.997	0.000
Q54.9 Hypospadias, unspecified	0.003	0.997	0.000
Q24.6 Congenital heart block	0.003	0.997	0.000
G21.9 Secondary Parkinsonism, unspecified	0.003	0.997	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.003	0.997	0.000
G23.3 Multiple system atrophy, cerebellar type	0.003	0.997	0.000
G23.2 Striatonigral degeneration	0.003	0.997	0.000
G23.0 Hallervorden-Spatz disease	0.003	0.997	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.003	0.997	0.000
Q50.3 Other congenital malformations of ovary	0.003	0.997	0.000
Q50.2 Congenital torsion of ovary	0.003	0.997	0.000
Q50.1 Developmental ovarian cyst	0.003	0.997	0.000
Q50.0 Congenital absence of ovary	0.003	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.003	0.997	0.000
Q24.8 Other specified congenital malformations of heart	0.003	0.997	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.003	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.003	0.997	0.000
K86.2 Cyst of pancreas	0.003	0.997	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.003	0.997	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.000	0.997	0.003
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.000	0.997	0.002
D07.3 Other and unspecified female genital organs	0.003	0.997	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.002	0.997	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.002	0.997	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.002	0.997	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.002	0.997	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.002	0.997	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.002	0.997	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.002	0.997	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.002	0.997	0.000
M89.08 Algoneurodystrophy (Other)	0.000	0.997	0.002
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.000	0.997	0.002
M89.02 Algoneurodystrophy (Upper arm)	0.000	0.997	0.002
C16.9 Stomach, unspecified	0.003	0.997	0.000
Q54.8 Other hypospadias	0.002	0.997	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.002	0.997	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.997	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.997	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
Q03 Congenital hydrocephalus	0.002	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.003	0.997	0.000
D07.6 Other and unspecified male genital organs	0.002	0.997	0.000
D07.0 Endometrium	0.002	0.997	0.000
Q54.4 Congenital chordee	0.002	0.997	0.000
Q54.3 Hypospadias, perineal	0.002	0.997	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.997	0.000
H80 Otosclerosis	0.000	0.997	0.002
H90 Conductive and sensorineural hearing loss	0.000	0.997	0.003
Q05.4 Unspecified spina bifida with hydrocephalus	0.002	0.997	0.000
Q89.9 Congenital malformation, unspecified	0.001	0.997	0.002
Q89.8 Other specified congenital malformations	0.001	0.997	0.002
Q89.7 Multiple congenital malformations, not elsewhere classified	0.001	0.997	0.002
Q89.4 Conjoined twins	0.001	0.997	0.002
Q89.1 Congenital malformations of adrenal gland	0.001	0.997	0.002
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.997	0.002
Q24.3 Pulmonary infundibular stenosis	0.002	0.997	0.000
Q24.2 Cor triatriatum	0.002	0.997	0.000
Q24.1 Levocardia	0.002	0.997	0.000
Z80.5 Family history of malignant neoplasm of urinary tract	0.000	0.997	0.003
Q25 Congenital malformations of great arteries	0.002	0.997	0.000
Z51.8 Other specified medical care	0.003	0.997	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.000	0.998	0.002
S12.10 Fracture of second cervical vertebra (closed)	0.002	0.998	0.000
Q24.0 Dextrocardia	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
Q26 Congenital malformations of great veins	0.002	0.998	0.000
Q01 Encephalocele	0.002	0.998	0.000
Q00 Anencephaly and similar malformations	0.002	0.998	0.000
Q02 Microcephaly	0.002	0.998	0.000
D12.3 Transverse colon	0.000	0.998	0.002
Q89.3 Situs inversus	0.001	0.998	0.002
Q89.0 Congenital malformations of spleen	0.001	0.998	0.002
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.998	0.002
M89.09 Algoneurodystrophy (Site unspecified)	0.000	0.998	0.002
Q04.8 Other specified congenital malformations of brain	0.002	0.998	0.000
Q52.1 Doubling of vagina	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
Q07 Other congenital malformations of nervous system	0.002	0.998	0.000
B17.1 Acute hepatitis C	0.002	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
H53.9 Visual disturbance, unspecified	0.002	0.998	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.002	0.998	0.000
Q04.6 Congenital cerebral cysts	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.998	0.000
Q52.3 Imperforate hymen	0.002	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.002	0.998	0.000
Q52.0 Congenital absence of vagina	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.000	0.998	0.002
D07.2 Vagina	0.002	0.998	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.002	0.998	0.000
Z34.8 Supervision of other normal pregnancy	0.000	0.998	0.002
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.998	0.002
N83.1 Corpus luteum cyst	0.002	0.998	0.000
Q54.0 Hypospadias, balanic	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
Q25.0 Patent ductus arteriosus	0.002	0.998	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.000	0.998	0.002
M89.07 Algoneurodystrophy (Ankle and foot)	0.000	0.998	0.002
Q54.1 Hypospadias, penile	0.002	0.998	0.000
Q04.9 Congenital malformation of brain, unspecified	0.002	0.998	0.000
Q04.5 Megalencephaly	0.002	0.998	0.000
Q04.4 Septo-optic dysplasia	0.002	0.998	0.000
Q04.3 Other reduction deformities of brain	0.002	0.998	0.000
Q04.2 Holoprosencephaly	0.002	0.998	0.000
Q04.1 Arhinencephaly	0.002	0.998	0.000
Q04.0 Congenital malformations of corpus callosum	0.002	0.998	0.000
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
Q61 Cystic kidney disease	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.998	0.002
K26.3 Acute without haemorrhage or perforation	0.002	0.998	0.000
R59.0 Localised enlarged lymph nodes	0.002	0.998	0.000
Q25.1 Coarctation of aorta	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.998	0.002
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.998	0.002
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.002	0.998	0.000
Q03.8 Other congenital hydrocephalus	0.002	0.998	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.002	0.998	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.002	0.998	0.000
Q27.4 Congenital phlebectasia	0.002	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.998	0.000
K65 Peritonitis	0.002	0.998	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.998	0.002
V49.9 Car occupant [any] injured in unspecified traffic accident	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
H80.8 Other otosclerosis	0.000	0.998	0.002
H80.2 Cochlear otosclerosis	0.000	0.998	0.002
H80.1 Otosclerosis involving oval window, obliterative	0.000	0.998	0.002
Q80-Q89 Other congenital malformations	0.002	0.998	0.001
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.000	0.998	0.002
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
Q07.8 Other specified congenital malformations of nervous system	0.002	0.998	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.002	0.998	0.000
Q25.8 Other congenital malformations of great arteries	0.002	0.998	0.000
Q25.6 Stenosis of pulmonary artery	0.002	0.998	0.000
Q25.5 Atresia of pulmonary artery	0.002	0.998	0.000
Q25.2 Atresia of aorta	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.002	0.998	0.000
K86.3 Pseudocyst of pancreas	0.002	0.998	0.000
Q25.3 Stenosis of aorta	0.002	0.998	0.000
Q87.4 Marfan's syndrome	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
Q96 Turner's syndrome	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
N60.4 Mammary duct ectasia	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
K65.8 Other peritonitis	0.002	0.998	0.000
Q00.2 Iniencephaly	0.002	0.998	0.000
Q00.1 Craniorachischisis	0.002	0.998	0.000
Q00.0 Anencephaly	0.002	0.998	0.000
Q01.9 Encephalocele, unspecified	0.002	0.998	0.000
Q01.8 Encephalocele of other sites	0.002	0.998	0.000
Q01.2 Occipital encephalocele	0.002	0.998	0.000
Q01.1 Nasofrontal encephalocele	0.002	0.998	0.000
Q01.0 Frontal encephalocele	0.002	0.998	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.998	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.998	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.998	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.998	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.998	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.998	0.000
Q26.1 Persistent left superior vena cava	0.002	0.998	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.998	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
K86.9 Disease of pancreas, unspecified	0.002	0.998	0.000
Q25.4 Other congenital malformations of aorta	0.002	0.998	0.000
Q52.5 Fusion of labia	0.002	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.002	0.998	0.000
Q76.5 Cervical rib	0.002	0.998	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.002	0.998	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
Q90 Down's syndrome	0.002	0.998	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.002	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.002	0.998	0.000
Q30 Congenital malformations of nose	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.998	0.002
Q66.7 Pes cavus	0.002	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.002	0.998	0.000
Q99.8 Other specified chromosome abnormalities	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
K51.5 Mucosal proctocolitis	0.000	0.998	0.002
Q06.9 Congenital malformation of spinal cord, unspecified	0.002	0.998	0.000
Q06.4 Hydromyelia	0.002	0.998	0.000
Q06.3 Other congenital cauda equina malformations	0.002	0.998	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.002	0.998	0.000
Q06.0 Amyelia	0.002	0.998	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.998	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.998	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.998	0.000
Q20.4 Double inlet ventricle	0.002	0.998	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.998	0.000
Q20.2 Double outlet left ventricle	0.002	0.998	0.000
Q20.1 Double outlet right ventricle	0.002	0.998	0.000
Q20.0 Common arterial trunk	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.998	0.000
Q33 Congenital malformations of lung	0.002	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.998	0.002
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.998	0.000
Q76.7 Congenital malformation of sternum	0.002	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.002	0.998	0.000
F43.0 Acute stress reaction	0.000	0.998	0.002
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
H92.1 Otorrhoea	0.000	0.998	0.002
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.998	0.002
Q06.2 Diastematomyelia	0.002	0.998	0.000
Q96.9 Turner's syndrome, unspecified	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.002	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
Q36 Cleft lip	0.002	0.998	0.000
Q35 Cleft palate	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.998	0.002
Y42.2 Antithyroid drugs	0.000	0.998	0.002
Q65 Congenital deformities of hip	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.001	0.998	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.998	0.002
Q61.0 Congenital single renal cyst	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.000	0.998	0.002
I95.9 Hypotension, unspecified	0.002	0.998	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.998	0.002
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
H50.0 Convergent concomitant strabismus	0.000	0.998	0.002
Q06.8 Other specified congenital malformations of spinal cord	0.001	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
Q99.9 Chromosomal abnormality, unspecified	0.002	0.998	0.000
Q99.2 Fragile X chromosome	0.002	0.998	0.000
Q99.1 46,XX true hermaphrodite	0.002	0.998	0.000
Q99.0 Chimera 46,XX/46,XY	0.002	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.001	0.998	0.001
Q84 Other congenital malformations of integument	0.001	0.998	0.001
Q81 Epidermolysis bullosa	0.001	0.998	0.001
Q80 Congenital ichthyosis	0.001	0.998	0.001
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.998	0.002
Q30.9 Congenital malformation of nose, unspecified	0.002	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.002	0.998	0.000
G20 Parkinson's disease	0.002	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.000	0.998	0.002
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.002	0.998	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.002	0.998	0.000
Q22.6 Hypoplastic right heart syndrome	0.002	0.998	0.000
Q22.4 Congenital tricuspid stenosis	0.002	0.998	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.002	0.998	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.002	0.998	0.000
Q22.0 Pulmonary valve atresia	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
Q96.8 Other variants of Turner's syndrome	0.002	0.998	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.002	0.998	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations