TreeWAS – Variant ID: rs1959122

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z87.1 Personal history of diseases of the digestive system	0.074	0.926	0.000
Z87 Personal history of other diseases and conditions	0.061	0.939	0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.057	0.943	0.000
Z87.4 Personal history of diseases of the genito-urinary system	0.053	0.947	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.048	0.952	0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.045	0.955	0.000
Z87.6 Personal history of certain conditions arising in the perinatal period	0.044	0.955	0.000
Z87.8 Personal history of other specified conditions	0.042	0.958	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.039	0.961	0.000
Z87.0 Personal history of diseases of the respiratory system	0.038	0.962	0.000
M25 Other joint disorders, not elsewhere classified	0.026	0.974	0.000
M20-M25 Other joint disorders	0.025	0.975	0.000
M25.5 Pain in joint	0.023	0.977	0.000
M22 Disorders of patella	0.022	0.978	0.000
M17.9 Gonarthrosis, unspecified	0.022	0.978	0.000
M20 Acquired deformities of fingers and toes	0.022	0.978	0.000
M25.8 Other specified joint disorders	0.022	0.978	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.022	0.978	0.000
M20.2 Hallux rigidus	0.021	0.979	0.000
M23 Internal derangement of knee	0.021	0.979	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.021	0.979	0.000
M25.7 Osteophyte	0.021	0.979	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.021	0.979	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.021	0.979	0.000
M15-M19 Arthrosis	0.021	0.979	0.000
M21 Other acquired deformities of limbs	0.020	0.980	0.000
M17 Gonarthrosis [arthrosis of knee]	0.020	0.980	0.000
M25.4 Effusion of joint	0.020	0.980	0.000
M25.56 Pain in joint (Lower leg)	0.020	0.980	0.000
M45-M49 Spondylopathies	0.019	0.981	0.000
M24 Other specific joint derangements	0.019	0.981	0.000
M31 Other necrotising vasculopathies	0.019	0.981	0.000
M25.9 Joint disorder, unspecified	0.019	0.981	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.019	0.981	0.000
M25.2 Flail joint	0.019	0.981	0.000
M25.1 Fistula of joint	0.019	0.981	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.018	0.981	0.000
M25.53 Pain in joint (Forearm)	0.018	0.981	0.000
M25.0 Haemarthrosis	0.018	0.982	0.000
M25.77 Osteophyte (Ankle and foot)	0.018	0.982	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.018	0.982	0.000
M25.3 Other instability of joint	0.018	0.982	0.000
M30 Polyarteritis nodosa and related conditions	0.018	0.982	0.000
M65-M68 Disorders of synovium and tendon	0.018	0.982	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.018	0.982	0.000
M25.51 Pain in joint (Shoulder region)	0.018	0.982	0.000
M22.4 Chondromalacia patellae	0.018	0.982	0.000
M32 Systemic lupus erythematosus	0.018	0.982	0.000
M19 Other arthrosis	0.018	0.982	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.982	0.018
M70-M79 Other soft tissue disorders	0.018	0.982	0.000
M25.50 Pain in joint (Multiple sites)	0.018	0.982	0.000
M25.54 Pain in joint (Hand)	0.017	0.982	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.017	0.983	0.000
M25.86 Other specified joint disorders (Lower leg)	0.017	0.983	0.000
M25.84 Other specified joint disorders (Hand)	0.017	0.983	0.000
M47 Spondylosis	0.017	0.983	0.000
M20.3 Other deformity of hallux (acquired)	0.017	0.983	0.000
M25.58 Pain in joint (Other)	0.017	0.983	0.000
M34 Systemic sclerosis	0.017	0.983	0.000
M22.2 Patellofemoral disorders	0.017	0.983	0.000
M25.52 Pain in joint (Upper arm)	0.017	0.983	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.017	0.983	0.000
M22.3 Other derangements of patella	0.017	0.983	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.016	0.983	0.000
M33 Dermatopolymyositis	0.016	0.983	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.016	0.984	0.000
M35 Other systemic involvement of connective tissue	0.016	0.984	0.000
M47.8 Other spondylosis	0.016	0.984	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.016	0.984	0.000
M46 Other inflammatory spondylopathies	0.016	0.984	0.000
M65 Synovitis and tenosynovitis	0.016	0.984	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.016	0.984	0.000
M25.74 Osteophyte (Hand)	0.016	0.984	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.016	0.984	0.000
M25.59 Pain in joint (Site unspecified)	0.016	0.984	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.016	0.984	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.016	0.984	0.000
M25.57 Pain in joint (Ankle and foot)	0.016	0.984	0.000
M22.0 Recurrent dislocation of patella	0.016	0.984	0.000
M79.8 Other specified soft tissue disorders	0.016	0.984	0.000
M60-M63 Disorders of muscles	0.016	0.984	0.000
M25.83 Other specified joint disorders (Forearm)	0.016	0.984	0.000
M22.8 Other disorders of patella	0.016	0.984	0.000
M21.0 Valgus deformity, not elsewhere classified	0.016	0.984	0.000
M22.9 Disorder of patella, unspecified	0.016	0.984	0.000
M25.88 Other specified joint disorders (Other)	0.016	0.984	0.000
M47.82 Other spondylosis (Cervical region)	0.016	0.984	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.016	0.984	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.016	0.984	0.000
M22.1 Recurrent subluxation of patella	0.016	0.984	0.000
M25.82 Other specified joint disorders (Upper arm)	0.016	0.984	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.016	0.984	0.000
M25.78 Osteophyte (Other)	0.016	0.984	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.016	0.984	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.016	0.984	0.000
M23.1 Discoid meniscus (congenital)	0.016	0.984	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.016	0.984	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.016	0.984	0.000
M20.0 Deformity of finger(s)	0.016	0.984	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.016	0.984	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.016	0.984	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.015	0.984	0.000
M00-M03 Infectious arthropathies	0.016	0.984	0.000
M23.0 Cystic meniscus	0.015	0.984	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.015	0.984	0.000
M21.3 Wrist or foot drop (acquired)	0.015	0.984	0.000
M23.5 Chronic instability of knee	0.015	0.984	0.000
M24.2 Disorder of ligament	0.015	0.984	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.015	0.984	0.000
M21.6 Other acquired deformities of ankle and foot	0.015	0.984	0.000
M21.2 Flexion deformity	0.015	0.984	0.000
M91-M94 Chondropathies	0.015	0.985	0.000
M15 Polyarthrosis	0.015	0.985	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.015	0.985	0.000
M25.70 Osteophyte (Multiple sites)	0.015	0.985	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.015	0.985	0.000
M21.4 Flat foot [pes planus] (acquired)	0.015	0.985	0.000
M23.9 Internal derangement of knee, unspecified	0.015	0.985	0.000
M21.8 Other specified acquired deformities of limbs	0.015	0.985	0.000
M17.3 Other posttraumatic gonarthrosis	0.015	0.985	0.000
M86-M90 Other osteopathies	0.015	0.985	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.015	0.985	0.000
M06.9 Rheumatoid arthritis, unspecified	0.001	0.985	0.014
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.015	0.985	0.000
M48 Other spondylopathies	0.015	0.985	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.015	0.985	0.000
M25.79 Osteophyte (Site unspecified)	0.015	0.985	0.000
M25.73 Osteophyte (Forearm)	0.015	0.985	0.000
M25.72 Osteophyte (Upper arm)	0.015	0.985	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.015	0.985	0.000
M05-M14 Inflammatory polyarthropathies	0.013	0.985	0.002
M25.42 Effusion of joint (Upper arm)	0.015	0.985	0.000
M25.40 Effusion of joint (Multiple sites)	0.015	0.985	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.015	0.985	0.000
M25.44 Effusion of joint (Hand)	0.015	0.985	0.000
M17.5 Other secondary gonarthrosis	0.015	0.985	0.000
M23.4 Loose body in knee	0.014	0.985	0.000
M25.46 Effusion of joint (Lower leg)	0.015	0.985	0.000
M25.41 Effusion of joint (Shoulder region)	0.015	0.985	0.000
M19.1 Posttraumatic arthrosis of other joints	0.015	0.985	0.000
M19.9 Arthrosis, unspecified	0.015	0.985	0.000
M49 Spondylopathies in diseases classified elsewhere	0.014	0.985	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.014	0.985	0.000
M25.49 Effusion of joint (Site unspecified)	0.014	0.985	0.000
M25.48 Effusion of joint (Other)	0.014	0.985	0.000
M25.47 Effusion of joint (Ankle and foot)	0.014	0.985	0.000
M24.5 Contracture of joint	0.014	0.985	0.000
M21.1 Varus deformity, not elsewhere classified	0.014	0.985	0.000
M21.7 Unequal limb length (acquired)	0.014	0.986	0.000
M24.1 Other articular cartilage disorders	0.014	0.986	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.014	0.986	0.000
M25.76 Osteophyte (Lower leg)	0.014	0.986	0.000
M24.9 Joint derangement, unspecified	0.014	0.986	0.000
M80-M85 Disorders of bone density and structure	0.014	0.986	0.000
M25.43 Effusion of joint (Forearm)	0.014	0.986	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.014	0.986	0.000
M31.9 Necrotising vasculopathy, unspecified	0.014	0.986	0.000
M31.1 Thrombotic microangiopathy	0.014	0.986	0.000
M31.0 Hypersensitivity angiitis	0.014	0.986	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.014	0.986	0.000
M25.94 Joint disorder, unspecified (Hand)	0.014	0.986	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.014	0.986	0.000
M24.0 Loose body in joint	0.014	0.986	0.000
M31.7 Microscopic polyangiitis	0.014	0.986	0.000
M31.8 Other specified necrotising vasculopathies	0.014	0.986	0.000
M31.3 Wegener's granulomatosis	0.014	0.986	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.014	0.986	0.000
M24.7 Protrusio acetabuli	0.014	0.986	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.014	0.986	0.000
M31.2 Lethal midline granuloma	0.014	0.986	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.014	0.986	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.014	0.986	0.000
M21.9 Acquired deformity of limb, unspecified	0.014	0.986	0.000
M25.98 Joint disorder, unspecified (Other)	0.014	0.986	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.014	0.986	0.000
M25.71 Osteophyte (Shoulder region)	0.014	0.986	0.000
M31.6 Other giant cell arteritis	0.014	0.986	0.000
M25.19 Fistula of joint (Site unspecified)	0.014	0.986	0.000
M25.18 Fistula of joint (Other)	0.014	0.986	0.000
M25.17 Fistula of joint (Ankle and foot)	0.014	0.986	0.000
M25.16 Fistula of joint (Lower leg)	0.014	0.986	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.014	0.986	0.000
M25.14 Fistula of joint (Hand)	0.014	0.986	0.000
M25.13 Fistula of joint (Forearm)	0.014	0.986	0.000
M25.12 Fistula of joint (Upper arm)	0.014	0.986	0.000
M25.11 Fistula of joint (Shoulder region)	0.014	0.986	0.000
M25.10 Fistula of joint (Multiple sites)	0.014	0.986	0.000
M25.29 Flail joint (Site unspecified)	0.014	0.986	0.000
M25.28 Flail joint (Other)	0.014	0.986	0.000
M25.27 Flail joint (Ankle and foot)	0.014	0.986	0.000
M25.26 Flail joint (Lower leg)	0.014	0.986	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.014	0.986	0.000
M25.24 Flail joint (Hand)	0.014	0.986	0.000
M25.23 Flail joint (Forearm)	0.014	0.986	0.000
M25.22 Flail joint (Upper arm)	0.014	0.986	0.000
M25.21 Flail joint (Shoulder region)	0.014	0.986	0.000
M25.20 Flail joint (Multiple sites)	0.014	0.986	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.014	0.986	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.014	0.986	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.013	0.986	0.000
M79.1 Myalgia	0.014	0.986	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.014	0.986	0.000
M19.0 Primary arthrosis of other joints	0.014	0.986	0.000
M66 Spontaneous rupture of synovium and tendon	0.013	0.986	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.013	0.986	0.000
M36.3 Arthropathy in other blood disorders	0.013	0.986	0.000
M36.2 Haemophilic arthropathy	0.013	0.986	0.000
M36.1 Arthropathy in neoplastic disease	0.013	0.986	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.013	0.986	0.000
M77 Other enthesopathies	0.013	0.986	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.013	0.986	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.013	0.986	0.000
M25.37 Other instability of joint (Ankle and foot)	0.013	0.986	0.000
M25.33 Other instability of joint (Forearm)	0.013	0.986	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.013	0.986	0.000
M19.2 Other secondary arthrosis	0.013	0.986	0.000
M20.5 Other deformities of toe(s) (acquired)	0.013	0.986	0.000
M23.8 Other internal derangements of knee	0.013	0.986	0.000
M24.6 Ankylosis of joint	0.013	0.986	0.000
M25.09 Haemarthrosis (Site unspecified)	0.013	0.987	0.000
M25.08 Haemarthrosis (Other)	0.013	0.987	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.013	0.987	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.013	0.987	0.000
M25.04 Haemarthrosis (Hand)	0.013	0.987	0.000
M25.03 Haemarthrosis (Forearm)	0.013	0.987	0.000
M25.02 Haemarthrosis (Upper arm)	0.013	0.987	0.000
M25.01 Haemarthrosis (Shoulder region)	0.013	0.987	0.000
M25.00 Haemarthrosis (Multiple sites)	0.013	0.987	0.000
M79.7 Fibromyalgia	0.013	0.987	0.000
M06 Other rheumatoid arthritis	0.005	0.987	0.008
M17.0 Primary gonarthrosis, bilateral	0.013	0.987	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.013	0.987	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.013	0.987	0.000
M25.39 Other instability of joint (Site unspecified)	0.013	0.987	0.000
M25.38 Other instability of joint (Other)	0.013	0.987	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.013	0.987	0.000
M25.32 Other instability of joint (Upper arm)	0.013	0.987	0.000
M25.31 Other instability of joint (Shoulder region)	0.013	0.987	0.000
M25.30 Other instability of joint (Multiple sites)	0.013	0.987	0.000
M47.89 Other spondylosis (Site unspecified)	0.013	0.987	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.013	0.987	0.000
M30.2 Juvenile polyarteritis	0.013	0.987	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.013	0.987	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.013	0.987	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.013	0.987	0.000
M18 Arthrosis of first carpometacarpal joint	0.013	0.987	0.000
M25.34 Other instability of joint (Hand)	0.013	0.987	0.000
M25.06 Haemarthrosis (Lower leg)	0.013	0.987	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.013	0.987	0.000
M47.1 Other spondylosis with myelopathy	0.013	0.987	0.000
M16 Coxarthrosis [arthrosis of hip]	0.013	0.987	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.013	0.987	0.000
M99 Biomechanical lesions, not elsewhere classified	0.013	0.987	0.000
M30.0 Polyarteritis nodosa	0.013	0.987	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.013	0.987	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.013	0.987	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.013	0.987	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.013	0.987	0.000
M79.5 Residual foreign body in soft tissue	0.013	0.987	0.000
M50-M54 Other dorsopathies	0.013	0.987	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.013	0.987	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.013	0.987	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.013	0.987	0.000
M79.0 Rheumatism, unspecified	0.013	0.987	0.000
M32.8 Other forms of systemic lupus erythematosus	0.012	0.987	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.001	0.987	0.012
M19.90 Arthrosis, unspecified (Multiple sites)	0.013	0.987	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.012	0.987	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.012	0.987	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.012	0.987	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.012	0.987	0.000
M25.36 Other instability of joint (Lower leg)	0.012	0.987	0.000
M35.7 Hypermobility syndrome	0.012	0.987	0.000
M65.3 Trigger finger	0.012	0.987	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.012	0.987	0.000
M76 Enthesopathies of lower limb, excluding foot	0.012	0.987	0.000
M35.1 Other overlap syndromes	0.012	0.988	0.000
M34.0 Progressive systemic sclerosis	0.012	0.988	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.012	0.988	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.012	0.988	0.000
M46.4 Discitis, unspecified	0.012	0.988	0.000
M47.84 Other spondylosis (Thoracic region)	0.012	0.988	0.000
M79.3 Panniculitis, unspecified	0.012	0.988	0.000
M19.8 Other specified arthrosis	0.012	0.988	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.012	0.988	0.000
M35.8 Other specified systemic involvement of connective tissue	0.012	0.988	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.012	0.988	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.012	0.988	0.000
M60 Myositis	0.012	0.988	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.012	0.988	0.000
M33.0 Juvenile dermatomyositis	0.012	0.988	0.000
M72 Fibroblastic disorders	0.012	0.988	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.012	0.988	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.012	0.988	0.000
M46.2 Osteomyelitis of vertebra	0.012	0.988	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.012	0.988	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.012	0.988	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.012	0.988	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.012	0.988	0.000
M35.5 Multifocal fibrosclerosis	0.012	0.988	0.000
M46.0 Spinal enthesopathy	0.012	0.988	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.012	0.988	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.012	0.988	0.000
M65.2 Calcific tendinitis	0.012	0.988	0.000
M62 Other disorders of muscle	0.012	0.988	0.000
M65.0 Abscess of tendon sheath	0.012	0.988	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.012	0.988	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.012	0.988	0.000
M46.8 Other specified inflammatory spondylopathies	0.012	0.988	0.000
M46.5 Other infective spondylopathies	0.012	0.988	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.012	0.988	0.000
M87 Osteonecrosis	0.012	0.988	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.012	0.988	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.012	0.988	0.000
M79.9 Soft tissue disorder, unspecified	0.012	0.988	0.000
M67 Other disorders of synovium and tendon	0.012	0.988	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.012	0.988	0.000
M65.1 Other infective (teno)synovitis	0.012	0.988	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.012	0.988	0.000
M61 Calcification and ossification of muscle	0.012	0.988	0.000
M75 Shoulder lesions	0.012	0.988	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.012	0.988	0.000
M34.9 Systemic sclerosis, unspecified	0.012	0.988	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.012	0.988	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.012	0.988	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.012	0.988	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.012	0.988	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.012	0.988	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.012	0.988	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.012	0.988	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.012	0.988	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.012	0.988	0.000
M07 Psoriatic and enteropathic arthropathies	0.011	0.988	0.001
M34.1 CR(E)ST syndrome	0.012	0.988	0.000
M92 Other juvenile osteochondrosis	0.012	0.988	0.000
M21.26 Flexion deformity (Lower leg)	0.012	0.988	0.000
M47.2 Other spondylosis with radiculopathy	0.012	0.988	0.000
M21.27 Flexion deformity (Ankle and foot)	0.012	0.988	0.000
M24.26 Disorder of ligament (Lower leg)	0.012	0.988	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.012	0.988	0.000
M24.24 Disorder of ligament (Hand)	0.012	0.988	0.000
M35.2 Behcet's disease	0.012	0.988	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.012	0.988	0.000
M40-M43 Deforming dorsopathies	0.011	0.988	0.000
M33.9 Dermatopolymyositis, unspecified	0.011	0.988	0.000
M79.2 Neuralgia and neuritis, unspecified	0.012	0.988	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.011	0.988	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.011	0.988	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.011	0.988	0.000
M15.1 Heberden's nodes (with arthropathy)	0.011	0.988	0.000
M65.8 Other synovitis and tenosynovitis	0.011	0.988	0.000
M02 Reactive arthropathies	0.011	0.988	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.001	0.988	0.011
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.011	0.988	0.000
M34.8 Other forms of systemic sclerosis	0.011	0.988	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.011	0.988	0.000
M24.21 Disorder of ligament (Shoulder region)	0.011	0.988	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.011	0.988	0.000
M35.0 Sicca syndrome [Sjogren]	0.011	0.988	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.011	0.988	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.011	0.988	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.011	0.988	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.011	0.988	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.011	0.988	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.011	0.988	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.011	0.988	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.011	0.988	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.011	0.988	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.011	0.988	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.011	0.988	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.011	0.988	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.011	0.988	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.011	0.988	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.011	0.988	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.011	0.988	0.000
M24.28 Disorder of ligament (Other)	0.011	0.988	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.011	0.988	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.011	0.988	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.011	0.988	0.000
M33.1 Other dermatomyositis	0.011	0.988	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.011	0.988	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.011	0.988	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.011	0.988	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.011	0.988	0.000
M15.8 Other polyarthrosis	0.011	0.988	0.000
M33.2 Polymyositis	0.011	0.988	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.011	0.988	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.011	0.988	0.000
M23.07 Cystic meniscus-Capsular lig	0.011	0.988	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.011	0.988	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.011	0.988	0.000
M23.00 Cystic meniscus (Multiple sites)	0.011	0.988	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.011	0.988	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.011	0.988	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.011	0.989	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.011	0.989	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.011	0.989	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.011	0.989	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.011	0.989	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.011	0.989	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.011	0.989	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.011	0.989	0.000
M19.94 Arthrosis, unspecified (Hand)	0.011	0.989	0.000
M21.23 Flexion deformity (Forearm)	0.011	0.989	0.000
M21.22 Flexion deformity (Upper arm)	0.011	0.989	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.011	0.989	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.011	0.989	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.011	0.989	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.011	0.989	0.000
M48.0 Spinal stenosis	0.011	0.989	0.000
M21.20 Flexion deformity (Multiple sites)	0.011	0.989	0.000
M24.29 Disorder of ligament (Site unspecified)	0.011	0.989	0.000
M24.22 Disorder of ligament (Upper arm)	0.011	0.989	0.000
M24.20 Disorder of ligament (Multiple sites)	0.011	0.989	0.000
M15.4 Erosive (osteo)arthrosis	0.011	0.989	0.000
M15.3 Secondary multiple arthrosis	0.011	0.989	0.000
M47.9 Spondylosis, unspecified	0.011	0.989	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.001	0.989	0.010
M15.9 Polyarthrosis, unspecified	0.011	0.989	0.000
M24.23 Disorder of ligament (Forearm)	0.011	0.989	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.011	0.989	0.000
M21.29 Flexion deformity (Site unspecified)	0.011	0.989	0.000
M21.28 Flexion deformity (Other)	0.011	0.989	0.000
M21.21 Flexion deformity (Shoulder region)	0.011	0.989	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.011	0.989	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.011	0.989	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.011	0.989	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.011	0.989	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.011	0.989	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.011	0.989	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.011	0.989	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.011	0.989	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.011	0.989	0.000
M15.0 Primary generalised (osteo)arthrosis	0.011	0.989	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.011	0.989	0.000
M79.88 Other specified soft tissue disorders (Other)	0.011	0.989	0.000
M71 Other bursopathies	0.011	0.989	0.000
M93 Other osteochondropathies	0.011	0.989	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.011	0.989	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.011	0.989	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.011	0.989	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.011	0.989	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.011	0.989	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.011	0.989	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.011	0.989	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.011	0.989	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.011	0.989	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.011	0.989	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.011	0.989	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.011	0.989	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.011	0.989	0.000
M11 Other crystal arthropathies	0.010	0.989	0.001
M21.83 Other specified acquired deformities of limbs (Forearm)	0.011	0.989	0.000
M00 Pyogenic arthritis	0.011	0.989	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.001	0.989	0.010
M90 Osteopathies in diseases classified elsewhere	0.011	0.989	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.011	0.989	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.011	0.989	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.011	0.989	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.011	0.989	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.011	0.989	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.011	0.989	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.011	0.989	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.011	0.989	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.011	0.989	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.011	0.989	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.011	0.989	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.011	0.989	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.011	0.989	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.011	0.989	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.011	0.989	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.011	0.989	0.000
M75.0 Adhesive capsulitis of shoulder	0.011	0.989	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.011	0.989	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.011	0.989	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.011	0.989	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.011	0.989	0.000
M05 Seropositive rheumatoid arthritis	0.010	0.989	0.001
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.001	0.989	0.010
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.011	0.989	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.011	0.989	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.011	0.989	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.011	0.989	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.011	0.989	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.011	0.989	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.011	0.989	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.011	0.989	0.000
M14 Arthropathies in other diseases classified elsewhere	0.010	0.989	0.002
M24.13 Other articular cartilage disorders (Forearm)	0.011	0.989	0.000
M48.4 Fatigue fracture of vertebra	0.011	0.989	0.000
M48.3 Traumatic spondylopathy	0.011	0.989	0.000
M48.2 Kissing spine	0.011	0.989	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.011	0.989	0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.011	0.989	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.011	0.989	0.000
M08 Juvenile arthritis	0.009	0.989	0.002
M94 Other disorders of cartilage	0.011	0.989	0.000
M23.49 Loose body in knee-Unspec lig/men	0.011	0.989	0.000
M12 Other specific arthropathies	0.009	0.989	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations