TreeWAS – Variant ID: rs1970584

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R60.0 Localised oedema	0.014	0.986	0.000
N92.6 Irregular menstruation, unspecified	0.012	0.988	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.010	0.990	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.009	0.991	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.009	0.991	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.008	0.992	0.000
R18 Ascites	0.008	0.992	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.008	0.992	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.007	0.993	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.007	0.993	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.007	0.993	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.994	0.006
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.006	0.994	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.006	0.994	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.000	0.994	0.006
G30 Alzheimer's disease	0.000	0.994	0.006
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.994	0.006
M54.22 Cervicalgia (Cervical region)	0.006	0.994	0.000
D05 Carcinoma in situ of breast	0.000	0.994	0.006
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.006	0.994	0.000
R60 Oedema, not elsewhere classified	0.006	0.994	0.000
D05.1 Intraductal carcinoma in situ	0.000	0.994	0.006
G30.0 Alzheimer's disease with early onset	0.000	0.995	0.005
G31.0 Circumscribed brain atrophy	0.000	0.995	0.005
G30-G32 Other degenerative diseases of the nervous system	0.000	0.995	0.005
G31.2 Degeneration of nervous system due to alcohol	0.000	0.995	0.005
G31.8 Other specified degenerative diseases of nervous system	0.000	0.995	0.005
D05.0 Lobular carcinoma in situ	0.000	0.995	0.005
N73.6 Female pelvic peritoneal adhesions	0.005	0.995	0.000
G30.1 Alzheimer's disease with late onset	0.000	0.995	0.005
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.995	0.005
D05.7 Other carcinoma in situ of breast	0.000	0.995	0.004
G30.8 Other Alzheimer's disease	0.000	0.995	0.004
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.996	0.004
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.996	0.004
R60.9 Oedema, unspecified	0.004	0.996	0.000
B95-B98 Bacterial, viral and other infectious agents	0.004	0.996	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.000	0.996	0.004
R60.1 Generalised oedema	0.004	0.996	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.996	0.004
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.996	0.004
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.004	0.996	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.996	0.004
D03 Melanoma in situ	0.000	0.996	0.004
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.004	0.996	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.997	0.003
K29.6 Other gastritis	0.003	0.997	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.003	0.997	0.000
D00-D09 In situ neoplasms	0.000	0.997	0.003
D03.6 Melanoma in situ of upper limb, including shoulder	0.000	0.997	0.003
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.003	0.997	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.003	0.997	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.000	0.997	0.003
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.003	0.997	0.000
D03.0 Melanoma in situ of lip	0.000	0.997	0.003
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.997	0.003
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.003	0.997	0.000
D03.9 Melanoma in situ, unspecified	0.000	0.997	0.003
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.003	0.997	0.000
D03.8 Melanoma in situ of other sites	0.000	0.997	0.003
M54.2 Cervicalgia	0.003	0.997	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.000	0.997	0.003
B97 Viral agents as the cause of diseases classified to other chapters	0.003	0.997	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.997	0.003
K60.2 Anal fissure, unspecified	0.003	0.997	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.000	0.997	0.003
D03.4 Melanoma in situ of scalp and neck	0.000	0.997	0.002
D50.9 Iron deficiency anaemia, unspecified	0.003	0.997	0.000
D09 Carcinoma in situ of other and unspecified sites	0.000	0.997	0.003
D02 Carcinoma in situ of middle ear and respiratory system	0.000	0.997	0.002
N18.3 Chronic kidney disease, stage 3	0.003	0.997	0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.002	0.997	0.000
D07.2 Vagina	0.000	0.997	0.002
F20.0 Paranoid schizophrenia	0.000	0.998	0.002
C18.9 Colon, unspecified	0.000	0.998	0.002
D01.2 Rectum	0.000	0.998	0.002
D07.4 Penis	0.000	0.998	0.002
Z92.4 Personal history of major surgery, not elsewhere classified	0.000	0.998	0.002
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.002	0.998	0.000
D07.5 Prostate	0.000	0.998	0.002
J84.1 Other interstitial pulmonary diseases with fibrosis	0.002	0.998	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.000	0.998	0.002
H02.3 Blepharochalasis	0.000	0.998	0.002
M54.29 Cervicalgia-Site unspe	0.002	0.998	0.000
C15.9 Oesophagus, unspecified	0.002	0.998	0.000
M54.27 Cervicalgia-Lumbosacral	0.002	0.998	0.000
M54.26 Cervicalgia-Lumbar	0.002	0.998	0.000
M54.25 Cervicalgia-Thoracolumbar	0.002	0.998	0.000
M54.24 Cervicalgia-Thoracic	0.002	0.998	0.000
M54.20 Cervicalgia-Mult site	0.002	0.998	0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
B97.5 Reovirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
C18.0 Caecum	0.000	0.998	0.002
D07.6 Other and unspecified male genital organs	0.000	0.998	0.002
M54.23 Cervicalgia (Cervicothoracic region)	0.002	0.998	0.000
D01.5 Liver, gallbladder and bile ducts	0.000	0.998	0.002
D01.9 Digestive organ, unspecified	0.000	0.998	0.002
D01.7 Other specified digestive organs	0.000	0.998	0.002
D01.4 Other and unspecified parts of intestine	0.000	0.998	0.002
D01.1 Rectosigmoid junction	0.000	0.998	0.002
M54.28 Cervicalgia-Sacral/sacrococ	0.002	0.998	0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.002	0.998	0.000
D01.3 Anus and anal canal	0.000	0.998	0.002
D01.0 Colon	0.000	0.998	0.002
D07.3 Other and unspecified female genital organs	0.000	0.998	0.002
D07.0 Endometrium	0.000	0.998	0.002
D09.9 Carcinoma in situ, unspecified	0.000	0.998	0.002
D04 Carcinoma in situ of skin	0.000	0.998	0.002
N73 Other female pelvic inflammatory diseases	0.002	0.998	0.000
D02.2 Bronchus and lung	0.000	0.998	0.002
D09.7 Carcinoma in situ of other specified sites	0.000	0.998	0.002
D09.3 Thyroid and other endocrine glands	0.000	0.998	0.002
D09.2 Eye	0.000	0.998	0.002
D02.4 Respiratory system, unspecified	0.000	0.998	0.002
D02.3 Other parts of respiratory system	0.000	0.998	0.002
D02.1 Trachea	0.000	0.998	0.002
D04.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
D09.1 Other and unspecified urinary organs	0.000	0.998	0.002
J06.9 Acute upper respiratory infection, unspecified	0.002	0.998	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
D07.1 Vulva	0.000	0.998	0.002
C15.5 Lower third of oesophagus	0.002	0.998	0.000
D09.0 Bladder	0.000	0.998	0.002
H35.3 Degeneration of macula and posterior pole	0.000	0.998	0.002
D03.5 Melanoma in situ of trunk	0.001	0.998	0.002
D06 Carcinoma in situ of cervix uteri	0.000	0.998	0.002
D02.0 Larynx	0.000	0.998	0.002
D00.2 Stomach	0.000	0.998	0.002
N73.5 Female pelvic peritonitis, unspecified	0.002	0.998	0.000
M75.5 Bursitis of shoulder	0.000	0.998	0.002
R47.0 Dysphasia and aphasia	0.000	0.998	0.002
N73.1 Chronic parametritis and pelvic cellulitis	0.002	0.998	0.000
C15 Malignant neoplasm of oesophagus	0.002	0.998	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.002	0.998	0.000
D00.0 Lip, oral cavity and pharynx	0.000	0.998	0.002
D04.1 Skin of eyelid, including canthus	0.000	0.998	0.002
D04.8 Skin of other sites	0.000	0.998	0.002
D04.0 Skin of lip	0.000	0.998	0.002
N73.4 Female chronic pelvic peritonitis	0.002	0.998	0.000
N73.3 Female acute pelvic peritonitis	0.002	0.998	0.000
N73.2 Unspecified parametritis and pelvic cellulitis	0.002	0.998	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.001	0.998	0.001
D00.1 Oesophagus	0.000	0.998	0.001
D04.2 Skin of ear and external auricular canal	0.000	0.998	0.002
D04.9 Skin, unspecified	0.000	0.998	0.002
N73.8 Other specified female pelvic inflammatory diseases	0.002	0.998	0.000
C15.4 Middle third of oesophagus	0.002	0.998	0.000
D04.5 Skin of trunk	0.000	0.998	0.002
N95.2 Postmenopausal atrophic vaginitis	0.000	0.998	0.002
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.998	0.002
H35.4 Peripheral retinal degeneration	0.000	0.998	0.002
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.998	0.002
F20 Schizophrenia	0.000	0.998	0.002
D04.4 Skin of scalp and neck	0.000	0.998	0.002
D06.7 Other parts of cervix	0.000	0.998	0.001
O63.0 Prolonged first stage (of labour)	0.000	0.998	0.002
D06.1 Exocervix	0.000	0.998	0.001
D06.0 Endocervix	0.000	0.998	0.001
M17.1 Other primary gonarthrosis	0.000	0.998	0.002
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
C15.1 Thoracic part of oesophagus	0.002	0.998	0.000
N73.0 Acute parametritis and pelvic cellulitis	0.001	0.998	0.000
C15.3 Upper third of oesophagus	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.000	0.998	0.002
C18 Malignant neoplasm of colon	0.000	0.998	0.002
S62.50 Fracture of thumb (closed)	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
C15.8 Overlapping lesion of oesophagus	0.001	0.998	0.000
C15.2 Abdominal part of oesophagus	0.001	0.998	0.000
C18.7 Sigmoid colon	0.000	0.998	0.002
C18.6 Descending colon	0.000	0.998	0.002
F20.8 Other schizophrenia	0.000	0.998	0.002
D04.3 Skin of other and unspecified parts of face	0.000	0.998	0.001
N73.9 Female pelvic inflammatory disease, unspecified	0.001	0.998	0.000
C15.0 Cervical part of oesophagus	0.001	0.998	0.000
C18.4 Transverse colon	0.000	0.998	0.002
F01.9 Vascular dementia, unspecified	0.000	0.998	0.002
F20.5 Residual schizophrenia	0.000	0.998	0.001
H35.2 Other proliferative retinopathy	0.000	0.998	0.001
K02.9 Dental caries, unspecified	0.000	0.998	0.002
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.998	0.001
D04.7 Skin of lower limb, including hip	0.000	0.998	0.001
F20.6 Simple schizophrenia	0.000	0.998	0.001
F20.4 Postschizophrenic depression	0.000	0.998	0.001
F20.3 Undifferentiated schizophrenia	0.000	0.998	0.001
F20.1 Hebephrenic schizophrenia	0.000	0.998	0.001
H35 Other retinal disorders	0.000	0.998	0.002
D75.2 Essential thrombocytosis	0.000	0.998	0.001
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.998	0.001
F20.2 Catatonic schizophrenia	0.000	0.999	0.001
O42.9 Premature rupture of membranes, unspecified	0.001	0.999	0.000
F02.0 Dementia in Pick's disease	0.000	0.999	0.001
S90 Superficial injury of ankle and foot	0.000	0.999	0.001
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.000	0.999	0.001
C18.8 Overlapping lesion of colon	0.000	0.999	0.001
C18.5 Splenic flexure	0.000	0.999	0.001
D32.9 Meninges, unspecified	0.000	0.999	0.001
K62.7 Radiation proctitis	0.000	0.999	0.001
S90.3 Contusion of other and unspecified parts of foot	0.000	0.999	0.001
Z99.8 Dependence on other enabling machines and devices	0.000	0.999	0.001
M62.89 Other specified disorders of muscle (Site unspecified)	0.000	0.999	0.001
H35.6 Retinal haemorrhage	0.000	0.999	0.001
S91.3 Open wound of other parts of foot	0.000	0.999	0.001
M06.34 Rheumatoid nodule (Hand)	0.000	0.999	0.001
D32.0 Cerebral meninges	0.000	0.999	0.001
H35.0 Background retinopathy and retinal vascular changes	0.000	0.999	0.001
N70.1 Chronic salpingitis and oophoritis	0.001	0.999	0.000
S90.0 Contusion of ankle	0.000	0.999	0.001
H35.7 Separation of retinal layers	0.000	0.999	0.001
H35.1 Retinopathy of prematurity	0.000	0.999	0.001
M41.99 Scoliosis, unspecified (Site unspecified)	0.001	0.999	0.000
C18.1 Appendix	0.000	0.999	0.001
H35.5 Hereditary retinal dystrophy	0.000	0.999	0.001
F01 Vascular dementia	0.000	0.999	0.001
D32.1 Spinal meninges	0.000	0.999	0.001
S90.8 Other superficial injuries of ankle and foot	0.000	0.999	0.001
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.999	0.001
S90.2 Contusion of toe(s) with damage to nail	0.000	0.999	0.001
S90.1 Contusion of toe(s) without damage to nail	0.000	0.999	0.001
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.999	0.001
Z50.8 Care involving use of rehabilitation procedures	0.000	0.999	0.001
D75 Other diseases of blood and blood-forming organs	0.000	0.999	0.001
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.000	0.999	0.001
D75.1 Secondary polycythaemia	0.000	0.999	0.001
F02.3 Dementia in Parkinson's disease	0.000	0.999	0.001
G50.0 Trigeminal neuralgia	0.001	0.999	0.000
O82.1 Delivery by emergency Caesarean section	0.001	0.999	0.000
S91 Open wound of ankle and foot	0.000	0.999	0.001
N92.4 Excessive bleeding in the premenopausal period	0.001	0.999	0.000
F02 Dementia in other diseases classified elsewhere	0.000	0.999	0.001
F01.1 Multi-infarct dementia	0.000	0.999	0.001
J18.0 Bronchopneumonia, unspecified	0.000	0.999	0.001
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.000	0.999	0.001
Z48.0 Attention to surgical dressings and sutures	0.000	0.999	0.001
F00 Dementia in Alzheimer's disease	0.000	0.999	0.001
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.999	0.001
K62.3 Rectal prolapse	0.001	0.999	0.000
N92.5 Other specified irregular menstruation	0.001	0.999	0.000
S91.2 Open wound of toe(s) with damage to nail	0.000	0.999	0.001
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.999	0.001
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.999	0.001
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.001	0.999	0.000
D75.0 Familial erythrocytosis	0.000	0.999	0.001
L94.0 Localised scleroderma [morphea]	0.000	0.999	0.001
M34.1 CR(E)ST syndrome	0.000	0.999	0.001
M41.9 Scoliosis, unspecified	0.001	0.999	0.000
R47.1 Dysarthria and anarthria	0.000	0.999	0.001
J06 Acute upper respiratory infections of multiple and unspecified sites	0.001	0.999	0.000
F01.8 Other vascular dementia	0.000	0.999	0.001
F01.3 Mixed cortical and subcortical vascular dementia	0.000	0.999	0.001
F01.2 Subcortical vascular dementia	0.000	0.999	0.001
F01.0 Vascular dementia of acute onset	0.000	0.999	0.001
L89.2 Stage III decubitus ulcer	0.001	0.999	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.999	0.001
M41.92 Scoliosis, unspecified (Cervical region)	0.001	0.999	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.000	0.999	0.001
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.999	0.001
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.000	0.999	0.001
F02.2 Dementia in Huntington's disease	0.000	0.999	0.001
F02.1 Dementia in Creutzfeldt-Jakob disease	0.000	0.999	0.001
S91.7 Multiple open wounds of ankle and foot	0.000	0.999	0.001
S91.1 Open wound of toe(s) without damage to nail	0.000	0.999	0.001
S91.0 Open wound of ankle	0.000	0.999	0.001
W07.9 Unspecified place	0.000	0.999	0.001
N92 Excessive, frequent and irregular menstruation	0.001	0.999	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.000	0.999	0.001
S92.51 Fracture of other toe (open)	0.000	0.999	0.001
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.999	0.001
G82.2 Paraplegia, unspecified	0.000	0.999	0.001
J06.0 Acute laryngopharyngitis	0.001	0.999	0.000
M34.8 Other forms of systemic sclerosis	0.000	0.999	0.001
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.001	0.999	0.000
S99.8 Other specified injuries of ankle and foot	0.000	0.999	0.001
J84 Other interstitial pulmonary diseases	0.001	0.999	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.000	0.999	0.001
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.000	0.999	0.001
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.000	0.999	0.001
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.000	0.999	0.001
S52.00 Fracture of upper end of ulna (closed)	0.001	0.999	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.001	0.999	0.000
D37.4 Colon	0.000	0.999	0.001
G61.0 Guillain-Barre syndrome	0.000	0.999	0.001
N18.5 Chronic kidney disease, stage 5	0.001	0.999	0.000
N70.0 Acute salpingitis and oophoritis	0.001	0.999	0.000
O82.0 Delivery by elective Caesarean section	0.001	0.999	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.999	0.001
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.999	0.001
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.999	0.001
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.999	0.001
M24.54 Contracture of joint (Hand)	0.000	0.999	0.001
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.001	0.999	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.000	0.999	0.001
S62.51 Fracture of thumb (open)	0.001	0.999	0.000
S92.50 Fracture of other toe (closed)	0.000	0.999	0.001
D13.1 Stomach	0.001	0.999	0.000
F52.2 Failure of genital response	0.000	0.999	0.001
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.999	0.001
J06.8 Other acute upper respiratory infections of multiple sites	0.001	0.999	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.999	0.001
D32 Benign neoplasm of meninges	0.000	0.999	0.001
N70 Salpingitis and oophoritis	0.001	0.999	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.999	0.001
M41.96 Scoliosis, unspecified (Lumbar region)	0.001	0.999	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.001	0.999	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.000	0.999	0.001
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
C18.3 Hepatic flexure	0.000	0.999	0.001
D06.9 Cervix, unspecified	0.000	0.999	0.001
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.999	0.001
H35.8 Other specified retinal disorders	0.000	0.999	0.001
K60.0 Acute anal fissure	0.001	0.999	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.001	0.999	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.001	0.999	0.000
N92.2 Excessive menstruation at puberty	0.001	0.999	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.001	0.999	0.000
S92.5 Fracture of other toe	0.000	0.999	0.001
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.999	0.001
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.999	0.001
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.999	0.001
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.001	0.999	0.000
M62.68 Muscle strain (Other)	0.000	0.999	0.001
M79.86 Other specified soft tissue disorders (Lower leg)	0.001	0.999	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.999	0.001
E14.9 Without complications	0.000	0.999	0.001
F33.1 Recurrent depressive disorder, current episode moderate	0.001	0.999	0.000
J84.8 Other specified interstitial pulmonary diseases	0.001	0.999	0.000
J84.0 Alveolar and parietoalveolar conditions	0.001	0.999	0.000
K60.4 Rectal fistula	0.001	0.999	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.001	0.999	0.000
Z90.6 Acquired absence of other parts of urinary tract	0.001	0.999	0.000
S99 Other and unspecified injuries of ankle and foot	0.000	0.999	0.001
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.999	0.001
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.999	0.001
F07.2 Postconcussional syndrome	0.000	0.999	0.001
S90-S99 Injuries to the ankle and foot	0.000	0.999	0.001
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.999	0.001
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.001	0.999	0.000
C77.2 Intra-abdominal lymph nodes	0.001	0.999	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.001	0.999	0.000
H35.9 Retinal disorder, unspecified	0.000	0.999	0.001
M34.9 Systemic sclerosis, unspecified	0.000	0.999	0.001
M62.8 Other specified disorders of muscle	0.000	0.999	0.001
N18.2 Chronic kidney disease, stage 2	0.001	0.999	0.000
N18 Chronic renal failure	0.001	0.999	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.999	0.001
M06.33 Rheumatoid nodule (Forearm)	0.000	0.999	0.001
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.000	0.999	0.001
M62.84 Other specified disorders of muscle (Hand)	0.000	0.999	0.001
J18.1 Lobar pneumonia, unspecified	0.000	0.999	0.001
M06.3 Rheumatoid nodule	0.000	0.999	0.001
M24.1 Other articular cartilage disorders	0.000	0.999	0.001
M34.0 Progressive systemic sclerosis	0.000	0.999	0.001
N95.3 States associated with artificial menopause	0.000	0.999	0.001
O32.0 Maternal care for unstable lie	0.001	0.999	0.000
S62.5 Fracture of thumb	0.001	0.999	0.000
S99.7 Multiple injuries of ankle and foot	0.000	0.999	0.001
S98 Traumatic amputation of ankle and foot	0.000	0.999	0.001
S95 Injury of blood vessels at ankle and foot level	0.000	0.999	0.001
S94 Injury of nerves at ankle and foot level	0.000	0.999	0.001
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.000	0.999	0.001
J18.8 Other pneumonia, organism unspecified	0.000	0.999	0.001
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.001	0.999	0.000
M62.6 Muscle strain	0.000	0.999	0.001
N75.1 Abscess of Bartholin's gland	0.001	0.999	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
O42 Premature rupture of membranes	0.001	0.999	0.000
R47 Speech disturbances, not elsewhere classified	0.000	0.999	0.001
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.999	0.001
M06.38 Rheumatoid nodule (Other)	0.000	0.999	0.001
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.999	0.001
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.999	0.001
M07.39 Other psoriatic arthropathies (Site unspecified)	0.001	0.999	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.999	0.001
M24.18 Other articular cartilage disorders (Other)	0.000	0.999	0.001
M24.14 Other articular cartilage disorders (Hand)	0.000	0.999	0.001
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.999	0.001
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.999	0.001
M62.88 Other specified disorders of muscle (Other)	0.000	0.999	0.001
M62.83 Other specified disorders of muscle (Forearm)	0.000	0.999	0.001
S92.11 Fracture of talus (open)	0.000	0.999	0.001
H47.3 Other disorders of optic disk	0.000	0.999	0.001
N71.9 Inflammatory disease of uterus, unspecified	0.001	0.999	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.999	0.001
S94.8 Injury of other nerves at ankle and foot level	0.000	0.999	0.001
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.999	0.001
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.999	0.001
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.999	0.001
S94.1 Injury of medial plantar nerve	0.000	0.999	0.001
S94.0 Injury of lateral plantar nerve	0.000	0.999	0.001
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.999	0.001
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.999	0.001
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.999	0.001
S95.2 Injury of dorsal vein of foot	0.000	0.999	0.001
S95.1 Injury of plantar artery of foot	0.000	0.999	0.001
S95.0 Injury of dorsal artery of foot	0.000	0.999	0.001
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.999	0.001
S98.3 Traumatic amputation of other parts of foot	0.000	0.999	0.001
S98.2 Traumatic amputation of two or more toes	0.000	0.999	0.001
S98.1 Traumatic amputation of one toe	0.000	0.999	0.001
S98.0 Traumatic amputation of foot at ankle level	0.000	0.999	0.001
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.999	0.001
K60 Fissure and fistula of anal and rectal regions	0.001	0.999	0.000
S97 Crushing injury of ankle and foot	0.000	0.999	0.001
M62.69 Muscle strain (Site unspecified)	0.000	0.999	0.001
M62.67 Muscle strain (Ankle and foot)	0.000	0.999	0.001
M62.66 Muscle strain (Lower leg)	0.000	0.999	0.001
M62.65 Muscle strain (Pelvic region and thigh)	0.000	0.999	0.001
M62.64 Muscle strain (Hand)	0.000	0.999	0.001
M62.63 Muscle strain (Forearm)	0.000	0.999	0.001
M62.62 Muscle strain (Upper arm)	0.000	0.999	0.001
M62.61 Muscle strain (Shoulder region)	0.000	0.999	0.001
M62.60 Muscle strain (Multiple sites)	0.000	0.999	0.001
M62.87 Other specified disorders of muscle (Ankle and foot)	0.000	0.999	0.001
M62.82 Other specified disorders of muscle (Upper arm)	0.000	0.999	0.001
M62.80 Other specified disorders of muscle (Multiple sites)	0.000	0.999	0.001
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
D12.4 Descending colon	0.001	0.999	0.000
E55.9 Vitamin D deficiency, unspecified	0.001	0.999	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.999	0.001
F07.1 Postencephalitic syndrome	0.000	0.999	0.001
G96.0 Cerebrospinal fluid leak	0.000	0.999	0.001
N18.8 Other chronic renal failure	0.001	0.999	0.000
N95.1 Menopausal and female climacteric states	0.000	0.999	0.001
O32.2 Maternal care for transverse and oblique lie	0.001	0.999	0.000
S92.1 Fracture of talus	0.000	0.999	0.001
S97.0 Crushing injury of ankle	0.000	0.999	0.001
S99.9 Unspecified injury of ankle and foot	0.000	0.999	0.001
M41.86 Other forms of scoliosis (Lumbar region)	0.000	0.999	0.001
S92.10 Fracture of talus (closed)	0.000	0.999	0.001
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.999	0.001
C49.5 Connective and soft tissue of pelvis	0.000	0.999	0.001
F42.9 Obsessive-compulsive disorder, unspecified	0.000	0.999	0.001
G96.9 Disorder of central nervous system, unspecified	0.000	0.999	0.001
N30.1 Interstitial cystitis (chronic)	0.000	0.999	0.001
N75.0 Cyst of Bartholin's gland	0.001	0.999	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.001	0.999	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.001	0.999	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.999	0.001
O82.8 Other single delivery by Caesarean section	0.001	0.999	0.000
O82.2 Delivery by Caesarean hysterectomy	0.001	0.999	0.000
S92.2 Fracture of other tarsal bone(s)	0.000	0.999	0.001
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.999	0.001
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.999	0.001
S97.1 Crushing injury of toe(s)	0.000	0.999	0.001
Y42.5 Other oestrogens and progestogens	0.000	0.999	0.001
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.000	0.999	0.001
O82 Single delivery by Caesarean section	0.001	0.999	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.999	0.001
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.999	0.001
M24.23 Disorder of ligament (Forearm)	0.000	0.999	0.001
M62.86 Other specified disorders of muscle (Lower leg)	0.000	0.999	0.001
S72.10 Pertrochanteric fracture (closed)	0.000	0.999	0.001
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.999	0.001
S93.40 Sprain of unspecified ligament of ankle	0.000	0.999	0.001
D12.3 Transverse colon	0.001	0.999	0.000
G82.0 Flaccid paraplegia	0.000	0.999	0.001
I86.1 Scrotal varices	0.000	0.999	0.001
J30.1 Allergic rhinitis due to pollen	0.000	0.999	0.001
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.999	0.001
N28.9 Disorder of kidney and ureter, unspecified	0.001	0.999	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.001	0.999	0.000
S93.4 Sprain and strain of ankle	0.000	0.999	0.001
S93.5 Sprain and strain of toe(s)	0.000	0.999	0.001
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.999	0.001
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.000	0.999	0.001
M34 Systemic sclerosis	0.000	0.999	0.001
S92 Fracture of foot, except ankle	0.000	0.999	0.001
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.999	0.001
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)	0.000	0.999	0.001
M62.18 Other rupture of muscle (nontraumatic) (Other)	0.000	0.999	0.001
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)	0.000	0.999	0.001
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)	0.000	0.999	0.001
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.000	0.999	0.001
M62.14 Other rupture of muscle (nontraumatic) (Hand)	0.000	0.999	0.001
M62.13 Other rupture of muscle (nontraumatic) (Forearm)	0.000	0.999	0.001
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)	0.000	0.999	0.001
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.000	0.999	0.001
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)	0.000	0.999	0.001
M62.39 Immobility syndrome (paraplegic) (Site unspecified)	0.000	0.999	0.001
M62.38 Immobility syndrome (paraplegic) (Other)	0.000	0.999	0.001
M62.37 Immobility syndrome (paraplegic) (Ankle and foot)	0.000	0.999	0.001
M62.36 Immobility syndrome (paraplegic) (Lower leg)	0.000	0.999	0.001
M62.35 Immobility syndrome (paraplegic) (Pelvic region and thigh)	0.000	0.999	0.001
M62.34 Immobility syndrome (paraplegic) (Hand)	0.000	0.999	0.001
M62.33 Immobility syndrome (paraplegic) (Forearm)	0.000	0.999	0.001
M62.32 Immobility syndrome (paraplegic) (Upper arm)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations