TreeWAS – Variant ID: rs1995138

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N18.5 Chronic kidney disease, stage 5	0.020	0.980	0.000
N18.4 Chronic kidney disease, stage 4	0.019	0.981	0.000
N18 Chronic renal failure	0.018	0.982	0.000
N18.3 Chronic kidney disease, stage 3	0.017	0.983	0.000
C34.3 Lower lobe, bronchus or lung	0.017	0.983	0.000
N18.1 Chronic kidney disease, stage 1	0.013	0.987	0.000
N18.2 Chronic kidney disease, stage 2	0.013	0.987	0.000
N18.8 Other chronic renal failure	0.013	0.987	0.000
N18.0 End-stage renal disease	0.013	0.987	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.012	0.988	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.010	0.990	0.000
C34 Malignant neoplasm of bronchus and lung	0.010	0.990	0.000
O36.8 Maternal care for other specified foetal problems	0.000	0.990	0.010
O36 Maternal care for other known or suspected foetal problems	0.000	0.991	0.009
L89 Decubitus ulcer	0.009	0.991	0.000
S83.2 Tear of meniscus, current	0.009	0.991	0.000
L89.1 Stage II decubitus ulcer	0.009	0.991	0.000
O36.6 Maternal care for excessive foetal growth	0.000	0.992	0.008
C34.2 Middle lobe, bronchus or lung	0.008	0.992	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.008	0.992	0.000
L89.2 Stage III decubitus ulcer	0.008	0.992	0.000
C34.9 Bronchus or lung, unspecified	0.008	0.992	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.992	0.008
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.008	0.992	0.000
O36.9 Maternal care for foetal problem, unspecified	0.000	0.993	0.007
C34.8 Overlapping lesion of bronchus and lung	0.007	0.993	0.000
N18.9 Chronic renal failure, unspecified	0.007	0.993	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.007	0.993	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.007	0.993	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.993	0.007
C34.0 Main bronchus	0.007	0.993	0.000
E23.0 Hypopituitarism	0.007	0.993	0.000
D46 Myelodysplastic syndromes	0.007	0.993	0.000
O36.4 Maternal care for intra-uterine death	0.000	0.993	0.007
L89.0 Stage I decubitus ulcer and pressure area	0.007	0.993	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.993	0.007
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.993	0.007
O36.2 Maternal care for hydrops foetalis	0.000	0.993	0.007
O36.1 Maternal care for other isoimmunisation	0.000	0.993	0.007
O42 Premature rupture of membranes	0.000	0.993	0.007
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.007	0.993	0.000
L89.3 Stage IV decubitus ulcer	0.007	0.993	0.000
O36.5 Maternal care for poor foetal growth	0.000	0.993	0.007
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.007	0.993	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.993	0.007
Z51.3 Blood transfusion without reported diagnosis	0.007	0.993	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.007	0.993	0.000
D46.2 Refractory anaemia with excess of blasts	0.007	0.993	0.000
D48.7 Other specified sites	0.007	0.993	0.000
D47.1 Chronic myeloproliferative disease	0.007	0.993	0.000
C34.1 Upper lobe, bronchus or lung	0.007	0.993	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.994	0.006
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.006	0.994	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.006	0.994	0.000
D48.1 Connective and other soft tissue	0.006	0.994	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.006	0.994	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.006	0.994	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.006	0.994	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.006	0.994	0.000
Y43.3 Other antineoplastic drugs	0.006	0.994	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.006	0.994	0.000
I45.1 Other and unspecified right bundle-branch block	0.006	0.994	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.006	0.994	0.000
D37.7 Other digestive organs	0.006	0.994	0.000
O43 Placental disorders	0.000	0.994	0.006
O47 False labour	0.000	0.994	0.006
D46.9 Myelodysplastic syndrome, unspecified	0.006	0.994	0.000
Y48.3 Local anaesthetics	0.006	0.994	0.000
Y48 Anaesthetics and therapeutic gases	0.006	0.994	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.006	0.994	0.000
D45 Polycythaemia vera	0.006	0.994	0.000
D48.5 Skin	0.006	0.994	0.000
O30 Multiple gestation	0.000	0.994	0.006
O40 Polyhydramnios	0.000	0.994	0.006
Y40 Systemic antibiotics	0.006	0.994	0.000
D47.4 Osteomyelofibrosis	0.006	0.994	0.000
O41 Other disorders of amniotic fluid and membranes	0.000	0.994	0.006
Y40.0 Penicillins	0.006	0.994	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.006	0.994	0.000
D44.3 Pituitary gland	0.006	0.994	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.006	0.994	0.000
O48 Prolonged pregnancy	0.000	0.995	0.005
L80 Vitiligo	0.005	0.995	0.000
O43.8 Other placental disorders	0.000	0.995	0.005
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.005	0.995	0.000
E23 Hypofunction and other disorders of pituitary gland	0.005	0.995	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.005	0.995	0.000
Y43 Primarily systemic agents	0.005	0.995	0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.005	0.995	0.000
K50.9 Crohn's disease, unspecified	0.000	0.995	0.005
D46.7 Other myelodysplastic syndromes	0.005	0.995	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.005	0.995	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.005	0.995	0.000
D46.4 Refractory anaemia, unspecified	0.005	0.995	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.005	0.995	0.000
D46.1 Refractory anaemia with sideroblasts	0.005	0.995	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.005	0.995	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.005	0.995	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.995	0.005
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.005	0.995	0.000
D48.4 Peritoneum	0.005	0.995	0.000
D48.3 Retroperitoneum	0.005	0.995	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.005	0.995	0.000
L84 Corns and callosities	0.005	0.995	0.000
O47.0 False labour before 37 completed weeks of gestation	0.000	0.995	0.005
L98.7 Excessive and redundant skin and subcutaneous tissue	0.005	0.995	0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.005	0.995	0.000
L98.5 Mucinosis of skin	0.005	0.995	0.000
L98.3 Eosinophilic cellulitis [Wells]	0.005	0.995	0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.005	0.995	0.000
L98.1 Factitial dermatitis	0.005	0.995	0.000
D37.0 Lip, oral cavity and pharynx	0.005	0.995	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.005	0.995	0.000
O33 Maternal care for known or suspected disproportion	0.000	0.995	0.005
O31 Complications specific to multiple gestation	0.000	0.995	0.005
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.005	0.995	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.005	0.995	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.005	0.995	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.005	0.995	0.000
O30.0 Twin pregnancy	0.000	0.995	0.005
D37.9 Digestive organ, unspecified	0.005	0.995	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.995	0.005
Y48.4 Anaesthetic, unspecified	0.005	0.995	0.000
D37.5 Rectum	0.005	0.995	0.000
D37.1 Stomach	0.005	0.995	0.000
D39.1 Ovary	0.005	0.995	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.005	0.995	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
D37.6 Liver, gallbladder and bile ducts	0.005	0.995	0.000
D37.3 Appendix	0.005	0.995	0.000
D37.2 Small intestine	0.005	0.995	0.000
O45 Premature separation of placenta [abruptio placentae]	0.000	0.995	0.005
D48.6 Breast	0.005	0.995	0.000
Y40.5 Aminoglycosides	0.005	0.995	0.000
L98.0 Pyogenic granuloma	0.005	0.995	0.000
L93 Lupus erythematosus	0.005	0.995	0.000
D44.9 Endocrine gland, unspecified	0.005	0.995	0.000
D44.8 Pluriglandular involvement	0.005	0.995	0.000
D44.7 Aortic body and other paraganglia	0.005	0.995	0.000
D44.6 Carotid body	0.005	0.995	0.000
D44.5 Pineal gland	0.005	0.995	0.000
D44.4 Craniopharyngeal duct	0.005	0.995	0.000
D44.2 Parathyroid gland	0.005	0.995	0.000
D44.1 Adrenal gland	0.005	0.995	0.000
D44.0 Thyroid gland	0.005	0.995	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.005	0.995	0.000
L94 Other localised connective tissue disorders	0.005	0.995	0.000
O41.0 Oligohydramnios	0.000	0.995	0.005
L95 Vasculitis limited to skin, not elsewhere classified	0.005	0.995	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.005	0.995	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.004	0.995	0.000
L87 Transepidermal elimination disorders	0.004	0.995	0.000
L88 Pyoderma gangrenosum	0.004	0.995	0.000
L86 Keratoderma in diseases classified elsewhere	0.004	0.995	0.000
L83 Acanthosis nigricans	0.005	0.995	0.000
O43.1 Malformation of placenta	0.000	0.995	0.004
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.995	0.004
O43.9 Placental disorder, unspecified	0.000	0.995	0.004
O43.2 Morbidly adherent placenta	0.000	0.995	0.004
O43.0 Placental transfusion syndromes	0.000	0.995	0.004
E23.6 Other disorders of pituitary gland	0.004	0.995	0.000
L98.4 Chronic ulcer of skin, not elsewhere classified	0.004	0.995	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.004	0.995	0.000
Y40.8 Other systemic antibiotics	0.004	0.995	0.000
E23.2 Diabetes insipidus	0.004	0.995	0.000
Y48.5 Therapeutic gases	0.004	0.995	0.000
Y48.2 Other and unspecified general anaesthetics	0.004	0.995	0.000
Y48.1 Parenteral anaesthetics	0.004	0.995	0.000
Y48.0 Inhaled anaesthetics	0.004	0.995	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.004	0.996	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.004	0.996	0.000
D39.9 Female genital organ, unspecified	0.004	0.996	0.000
D39.7 Other female genital organs	0.004	0.996	0.000
D39.2 Placenta	0.004	0.996	0.000
D39.0 Uterus	0.004	0.996	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
D37.4 Colon	0.004	0.996	0.000
Y40.9 Systemic antibiotic, unspecified	0.004	0.996	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.004	0.996	0.000
E23.7 Disorder of pituitary gland, unspecified	0.004	0.996	0.000
O30.9 Multiple gestation, unspecified	0.000	0.996	0.004
O30.8 Other multiple gestation	0.000	0.996	0.004
O30.2 Quadruplet pregnancy	0.000	0.996	0.004
O30.1 Triplet pregnancy	0.000	0.996	0.004
Y42.7 Androgens and anabolic congeners	0.004	0.996	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.004	0.996	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
D43.2 Brain, unspecified	0.004	0.996	0.000
L40.9 Psoriasis, unspecified	0.004	0.996	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.996	0.004
Y40.7 Antifungal antibiotics, systemically used	0.004	0.996	0.000
Y40.6 Rifamycins	0.004	0.996	0.000
Y40.4 Tetracyclines	0.004	0.996	0.000
Y40.2 Chloramphenicol group	0.004	0.996	0.000
Y40.3 Macrolides	0.004	0.996	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.996	0.004
O41.1 Infection of amniotic sac and membranes	0.000	0.996	0.004
Y59 Other and unspecified vaccines and biological substances	0.004	0.996	0.000
Y58 Bacterial vaccines	0.004	0.996	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.004	0.996	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.004	0.996	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.004	0.996	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.004	0.996	0.000
L91 Hypertrophic disorders of skin	0.004	0.996	0.000
O47.9 False labour, unspecified	0.000	0.996	0.004
D43.9 Central nervous system, unspecified	0.004	0.996	0.000
D43.7 Other parts of central nervous system	0.004	0.996	0.000
D43.4 Spinal cord	0.004	0.996	0.000
D43.3 Cranial nerves	0.004	0.996	0.000
D43.1 Brain, infratentorial	0.004	0.996	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.004	0.996	0.000
E23.1 Drug-induced hypopituitarism	0.004	0.996	0.000
D42.9 Meninges, unspecified	0.004	0.996	0.000
D42.1 Spinal meninges	0.004	0.996	0.000
D42.0 Cerebral meninges	0.004	0.996	0.000
Y43.9 Primarily systemic agent, unspecified	0.004	0.996	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.004	0.996	0.000
Y43.6 Enzymes, not elsewhere classified	0.004	0.996	0.000
Y43.5 Acidifying and alkalising agents	0.004	0.996	0.000
Y43.2 Antineoplastic natural products	0.004	0.996	0.000
Y44 Agents primarily affecting blood constituents	0.004	0.996	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.996	0.004
Y52 Agents primarily affecting the cardiovascular system	0.004	0.996	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.004	0.996	0.000
D40.9 Male genital organ, unspecified	0.004	0.996	0.000
D40.7 Other male genital organs	0.004	0.996	0.000
D40.1 Testis	0.004	0.996	0.000
Y43.4 Immunosuppressive agents	0.004	0.996	0.000
Y46.2 Hydantoin derivatives	0.004	0.996	0.000
O31.8 Other complications specific to multiple gestation	0.000	0.996	0.004
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.000	0.996	0.004
O31.1 Continuing pregnancy after abortion of one foetus or more	0.000	0.996	0.004
O31.0 Papyraceous foetus	0.000	0.996	0.004
O33.9 Maternal care for disproportion, unspecified	0.000	0.996	0.004
O33.8 Maternal care for disproportion of other origin	0.000	0.996	0.004
O33.7 Maternal care for disproportion due to other foetal deformities	0.000	0.996	0.004
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.000	0.996	0.004
O33.5 Maternal care for disproportion due to unusually large foetus	0.000	0.996	0.004
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.000	0.996	0.004
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.000	0.996	0.004
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.000	0.996	0.004
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.000	0.996	0.004
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.000	0.996	0.004
O44 Placenta praevia	0.000	0.996	0.004
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.004	0.996	0.000
D43.0 Brain, supratentorial	0.004	0.996	0.000
L91.0 Keloid scar	0.004	0.996	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.004	0.996	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.996	0.004
D40.0 Prostate	0.004	0.996	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.004	0.996	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.004	0.996	0.000
L85 Other epidermal thickening	0.004	0.996	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.004	0.996	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.004	0.996	0.000
D47.2 Monoclonal gammopathy	0.004	0.996	0.000
D38.6 Respiratory organ, unspecified	0.004	0.996	0.000
D38.5 Other respiratory organs	0.004	0.996	0.000
D38.4 Thymus	0.004	0.996	0.000
D38.3 Mediastinum	0.004	0.996	0.000
D38.2 Pleura	0.004	0.996	0.000
D38.0 Larynx	0.004	0.996	0.000
L93.0 Discoid lupus erythematosus	0.004	0.996	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.004	0.996	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
Y51.0 Anticholinesterase agents	0.004	0.996	0.000
O45.8 Other premature separation of placenta	0.000	0.996	0.004
O45.0 Premature separation of placenta with coagulation defect	0.000	0.996	0.004
Z60.2 Living alone	0.000	0.996	0.004
D48.0 Bone and articular cartilage	0.003	0.996	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.004	0.996	0.000
Y47.1 Benzodiazepines	0.004	0.996	0.000
L92.0 Granuloma annulare	0.004	0.996	0.000
L94.2 Calcinosis cutis	0.004	0.996	0.000
Y46.4 Iminostilbenes	0.004	0.996	0.000
Y54.3 Benzothiadiazine derivatives	0.004	0.996	0.000
L93.2 Other local lupus erythematosus	0.003	0.996	0.000
L93.1 Subacute cutaneous lupus erythematosus	0.003	0.996	0.000
Y49.5 Other antipsychotics and neuroleptics	0.004	0.996	0.000
L95.9 Vasculitis limited to skin, unspecified	0.004	0.996	0.000
Y46.8 Antispasticity drugs	0.003	0.996	0.000
Y46.7 Anti-Parkinsonism drugs	0.003	0.996	0.000
Y46.6 Other and unspecified antiepileptics	0.003	0.996	0.000
Y46.5 Valproic acid	0.003	0.996	0.000
Y46.3 Deoxybarbiturates	0.003	0.996	0.000
Y46.1 Oxazolidinediones	0.003	0.996	0.000
Y46.0 Succinimides	0.003	0.996	0.000
L94.9 Localised connective tissue disorder, unspecified	0.003	0.996	0.000
L94.8 Other specified localised connective tissue disorders	0.003	0.996	0.000
L94.6 Ainhum	0.003	0.996	0.000
L94.5 Poikiloderma vasculare atrophicans	0.003	0.996	0.000
L94.4 Gottron's papules	0.003	0.996	0.000
L94.3 Sclerodactyly	0.003	0.996	0.000
L94.1 Linear scleroderma	0.003	0.996	0.000
L94.0 Localised scleroderma [morphea]	0.003	0.996	0.000
Y44.5 Thrombolytic drugs	0.003	0.996	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.996	0.000
L95.8 Other vasculitis limited to skin	0.003	0.996	0.000
L95.1 Erythema elevatum diutinum	0.003	0.996	0.000
L95.0 Livedoid vasculitis	0.003	0.996	0.000
S83.7 Injury to multiple structures of knee	0.003	0.996	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.003	0.996	0.000
S83.3 Tear of articular cartilage of knee, current	0.003	0.996	0.000
S83.1 Dislocation of knee	0.003	0.996	0.000
S83.0 Dislocation of patella	0.003	0.996	0.000
Y43.0 Antiallergic and antiemetic drugs	0.003	0.996	0.000
L20-L30 Dermatitis and eczema	0.004	0.996	0.000
L87.9 Transepidermal elimination disorder, unspecified	0.003	0.996	0.000
L87.8 Other transepidermal elimination disorders	0.003	0.996	0.000
L87.2 Elastosis perforans serpiginosa	0.003	0.996	0.000
L87.1 Reactive perforating collagenosis	0.003	0.996	0.000
L87.0 Keratosis follicularis et parafollicularis in cutem penetrans [Kyrle]	0.003	0.996	0.000
L99.8 Other specified disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.003	0.996	0.000
L99.0 Amyloidosis of skin	0.003	0.996	0.000
Y45.5 4-Aminophenol derivatives	0.003	0.996	0.000
O45.9 Premature separation of placenta, unspecified	0.000	0.996	0.003
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.996	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.996	0.003
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.996	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.996	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.003	0.996	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.003	0.996	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.003	0.996	0.000
Y47.4 Bromine compounds	0.003	0.996	0.000
Y47.3 Paraldehyde	0.003	0.996	0.000
Y47.2 Chloral derivatives	0.003	0.996	0.000
Y47.0 Barbiturates, not elsewhere classified	0.003	0.996	0.000
Y45.8 Other analgesics and antipyretics	0.003	0.996	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.003	0.996	0.000
L29 Pruritus	0.003	0.996	0.000
Y54.9 Mineral salts, not elsewhere classified	0.003	0.997	0.000
Y54.8 Agents affecting uric acid metabolism	0.003	0.997	0.000
Y54.7 Agents affecting calcification	0.003	0.997	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
Y54.4 Loop [high-ceiling] diuretics	0.003	0.997	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.003	0.997	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.003	0.997	0.000
Y54.0 Mineralocorticoids	0.003	0.997	0.000
Y56.9 Topical agent, unspecified	0.003	0.997	0.000
Y56.8 Other topical agents	0.003	0.997	0.000
Y56.7 Dental drugs, topically applied	0.003	0.997	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
Y56.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
Y56.3 Emollients, demulcents and protectants	0.003	0.997	0.000
Y56.2 Local astringents and local detergents	0.003	0.997	0.000
Y56.1 Antipruritics	0.003	0.997	0.000
L29.9 Pruritus, unspecified	0.003	0.997	0.000
Y43.1 Antineoplastic antimetabolites	0.003	0.997	0.000
L27 Dermatitis due to substances taken internally	0.003	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.003	0.997	0.000
Y42.2 Antithyroid drugs	0.003	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.003	0.997	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.997	0.003
K13.0 Diseases of lips	0.003	0.997	0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.003	0.997	0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.003	0.997	0.000
Y49.9 Psychotropic drug, unspecified	0.003	0.997	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
Y49.7 Psychostimulants with abuse potential	0.003	0.997	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.003	0.997	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
L81 Other disorders of pigmentation	0.003	0.997	0.000
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
E11.9 Without complications	0.003	0.997	0.000
K50.0 Crohn's disease of small intestine	0.000	0.997	0.003
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.997	0.003
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.997	0.003
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.997	0.003
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.997	0.003
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.997	0.003
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.997	0.003
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.997	0.003
Y54.5 Other diuretics	0.003	0.997	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.997	0.003
Y42.0 Glucocorticoids and synthetic analogs	0.003	0.997	0.000
Y50.9 Central nervous system stimulant, unspecified	0.003	0.997	0.000
Y50.8 Other central nervous system stimulants	0.003	0.997	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.003	0.997	0.000
Y50.1 Opioid receptor antagonists	0.003	0.997	0.000
Y50.0 Analeptics	0.003	0.997	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
Y53.7 Emetics	0.003	0.997	0.000
Y53.6 Antidiarrhoeal drugs	0.003	0.997	0.000
Y53.5 Digestants	0.003	0.997	0.000
Y53.4 Other laxatives	0.003	0.997	0.000
Y53.3 Saline and osmotic laxatives	0.003	0.997	0.000
Y53.2 Stimulant laxatives	0.003	0.997	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
Y53.0 Histamine H2-receptor antagonists	0.003	0.997	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
Y55.5 Anticommon cold drugs	0.003	0.997	0.000
Y55.4 Expectorants	0.003	0.997	0.000
Y55.3 Antitussives	0.003	0.997	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
Y55.0 Oxytocic drugs	0.003	0.997	0.000
Y58.9 Other and unspecified bacterial vaccines	0.003	0.997	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.003	0.997	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.003	0.997	0.000
Y58.5 Diphtheria vaccine	0.003	0.997	0.000
Y58.4 Tetanus vaccine	0.003	0.997	0.000
Y58.3 Plague vaccine	0.003	0.997	0.000
Y58.2 Cholera vaccine	0.003	0.997	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.003	0.997	0.000
Y58.0 BCG vaccine	0.003	0.997	0.000
Y59.9 Vaccine or biological substance, unspecified	0.003	0.997	0.000
Y59.8 Other specified vaccines and biological substances	0.003	0.997	0.000
Y59.3 Immunoglobulin	0.003	0.997	0.000
Y59.2 Protozoal vaccines	0.003	0.997	0.000
Y59.1 Rickettsial vaccines	0.003	0.997	0.000
Y59.0 Viral vaccines	0.003	0.997	0.000
D38.1 Trachea, bronchus and lung	0.003	0.997	0.000
L27.2 Dermatitis due to ingested food	0.003	0.997	0.000
L91.9 Hypertrophic disorder of skin, unspecified	0.003	0.997	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.003	0.997	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.997	0.003
I71 Aortic aneurysm and dissection	0.003	0.997	0.000
L10-L14 Bullous disorders	0.003	0.997	0.000
Y49.2 Other and unspecified antidepressants	0.003	0.997	0.000
L40-L45 Papulosquamous disorders	0.003	0.997	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.000	0.997	0.003
O34.8 Maternal care for other abnormalities of pelvic organs	0.000	0.997	0.003
O34.6 Maternal care for abnormality of vagina	0.000	0.997	0.003
O34.5 Maternal care for other abnormalities of gravid uterus	0.000	0.997	0.003
O34.4 Maternal care for other abnormalities of cervix	0.000	0.997	0.003
O34.3 Maternal care for cervical incompetence	0.000	0.997	0.003
O34.0 Maternal care for congenital malformation of uterus	0.000	0.997	0.003
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
Y41.5 Antiviral drugs	0.003	0.997	0.000
Y41.4 Anthelminthics	0.003	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.003	0.997	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
Y41.1 Antimycobacterial drugs	0.003	0.997	0.000
Y41.0 Sulphonamides	0.003	0.997	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.003	0.997	0.000
Y44.7 Plasma substitutes	0.003	0.997	0.000
Y44.6 Natural blood and blood products	0.003	0.997	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.003	0.997	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.003	0.997	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.003	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
Y52.7 Peripheral vasodilators	0.003	0.997	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
O34.1 Maternal care for tumour of corpus uteri	0.000	0.997	0.003
L21 Seborrhoeic dermatitis	0.003	0.997	0.000
L40 Psoriasis	0.003	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
Y45.0 Opioids and related analgesics	0.003	0.997	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.003	0.997	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
Y45.4 Antirheumatics	0.003	0.997	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.997	0.003
L27.1 Localised skin eruption due to drugs and medicaments	0.003	0.997	0.000
O46.8 Other antepartum haemorrhage	0.000	0.997	0.003
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.003	0.997	0.000
L85.3 Xerosis cutis	0.003	0.997	0.000
L85.2 Keratosis punctata (palmaris et plantaris)	0.003	0.997	0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.003	0.997	0.000
L85.0 Acquired ichthyosis	0.003	0.997	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.003	0.997	0.000
D41.9 Urinary organ, unspecified	0.003	0.997	0.000
D41.7 Other urinary organs	0.003	0.997	0.000
D41.3 Urethra	0.003	0.997	0.000
D41.2 Ureter	0.003	0.997	0.000
D41.1 Renal pelvis	0.003	0.997	0.000
L04 Acute lymphadenitis	0.003	0.997	0.000
L01 Impetigo	0.003	0.997	0.000
L00 Staphylococcal scalded skin syndrome	0.003	0.997	0.000
L81.2 Freckles	0.003	0.997	0.000
Y45.2 Propionic acid derivatives	0.003	0.997	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.003	0.997	0.000
C31 Malignant neoplasm of accessory sinuses	0.003	0.997	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.003	0.997	0.000
C37 Malignant neoplasm of thymus	0.003	0.997	0.000
C33 Malignant neoplasm of trachea	0.003	0.997	0.000
L29.2 Pruritus vulvae	0.003	0.997	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.997	0.003
L23 Allergic contact dermatitis	0.003	0.997	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.003	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
U80.1 Methicillin resistant agent	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations