TreeWAS – Variant ID: rs2001754

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D12.5 Sigmoid colon	1.000	0.000	0.000
D12.2 Ascending colon	1.000	0.000	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	1.000	0.000	0.000
D12.8 Rectum	1.000	0.000	0.000
D12.4 Descending colon	1.000	0.000	0.000
D12.3 Transverse colon	1.000	0.000	0.000
D12.6 Colon, unspecified	0.994	0.006	0.000
C18 Malignant neoplasm of colon	0.960	0.040	0.000
C15-C26 Malignant neoplasms of digestive organs	0.950	0.050	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.949	0.051	0.000
C18.3 Hepatic flexure	0.929	0.071	0.000
C18.9 Colon, unspecified	0.925	0.075	0.000
C20 Malignant neoplasm of rectum	0.920	0.080	0.000
C18.7 Sigmoid colon	0.913	0.087	0.000
C18.6 Descending colon	0.885	0.115	0.000
C18.4 Transverse colon	0.883	0.117	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.882	0.118	0.000
C26.0 Intestinal tract, part unspecified	0.831	0.169	0.000
C23 Malignant neoplasm of gallbladder	0.815	0.185	0.000
D12.0 Caecum	0.788	0.212	0.000
D12.7 Rectosigmoid junction	0.782	0.218	0.000
C18.8 Overlapping lesion of colon	0.759	0.241	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.730	0.270	0.000
C18.0 Caecum	0.728	0.272	0.000
D12.1 Appendix	0.694	0.306	0.000
C18.5 Splenic flexure	0.670	0.330	0.000
C26.9 Ill-defined sites within the digestive system	0.643	0.357	0.000
C22.9 Liver, unspecified	0.637	0.363	0.000
C26.8 Overlapping lesion of digestive system	0.632	0.368	0.000
C26.1 Spleen	0.632	0.368	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.556	0.443	0.000
C22.7 Other specified carcinomas of liver	0.523	0.476	0.000
C22.4 Other sarcomas of liver	0.523	0.476	0.000
C22.3 Angiosarcoma of liver	0.523	0.476	0.000
C22.2 Hepatoblastoma	0.523	0.476	0.000
D12.9 Anus and anal canal	0.509	0.491	0.000
C25 Malignant neoplasm of pancreas	0.505	0.495	0.000
K62.1 Rectal polyp	0.501	0.499	0.000
C22.1 Intrahepatic bile duct carcinoma	0.496	0.504	0.000
C18.1 Appendix	0.481	0.519	0.000
C17 Malignant neoplasm of small intestine	0.448	0.552	0.000
C24.9 Biliary tract, unspecified	0.439	0.561	0.000
C22.0 Liver cell carcinoma	0.422	0.578	0.000
C24.8 Overlapping lesion of biliary tract	0.399	0.601	0.000
C25.1 Body of pancreas	0.377	0.623	0.000
C25.3 Pancreatic duct	0.363	0.637	0.000
C25.8 Overlapping lesion of pancreas	0.362	0.638	0.000
C25.4 Endocrine pancreas	0.362	0.638	0.000
C25.7 Other parts of pancreas	0.352	0.648	0.000
C24.0 Extrahepatic bile duct	0.346	0.654	0.000
C17.9 Small intestine, unspecified	0.343	0.657	0.000
C25.9 Pancreas, unspecified	0.337	0.663	0.000
C21 Malignant neoplasm of anus and anal canal	0.335	0.664	0.001
C18.2 Ascending colon	0.323	0.677	0.000
C17.8 Overlapping lesion of small intestine	0.321	0.679	0.000
C17.3 Meckel's diverticulum	0.321	0.679	0.000
C25.0 Head of pancreas	0.313	0.687	0.000
C17.1 Jejunum	0.293	0.707	0.000
C25.2 Tail of pancreas	0.290	0.709	0.000
C24.1 Ampulla of Vater	0.275	0.725	0.000
C17.2 Ileum	0.256	0.743	0.000
C16 Malignant neoplasm of stomach	0.256	0.744	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.252	0.748	0.001
C21.2 Cloacogenic zone	0.240	0.759	0.001
C17.0 Duodenum	0.212	0.787	0.001
C16.5 Lesser curvature of stomach, unspecified	0.199	0.801	0.000
C16.6 Greater curvature of stomach, unspecified	0.190	0.810	0.000
C16.8 Overlapping lesion of stomach	0.183	0.817	0.000
C16.0 Cardia	0.176	0.824	0.000
C16.3 Pyloric antrum	0.171	0.828	0.000
C16.1 Fundus of stomach	0.159	0.841	0.000
C16.4 Pylorus	0.153	0.847	0.000
C21.0 Anus, unspecified	0.139	0.860	0.001
C16.9 Stomach, unspecified	0.124	0.876	0.000
K63.5 Polyp of colon	0.115	0.885	0.000
C15 Malignant neoplasm of oesophagus	0.112	0.887	0.001
C16.2 Body of stomach	0.108	0.891	0.001
C21.1 Anal canal	0.092	0.905	0.002
C15.3 Upper third of oesophagus	0.082	0.917	0.001
C15.8 Overlapping lesion of oesophagus	0.080	0.919	0.001
C15.2 Abdominal part of oesophagus	0.080	0.919	0.001
C15.1 Thoracic part of oesophagus	0.079	0.921	0.001
Z12.1 Special screening examination for neoplasm of intestinal tract	0.078	0.922	0.000
C15.0 Cervical part of oesophagus	0.072	0.927	0.001
C15.4 Middle third of oesophagus	0.060	0.939	0.001
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.039	0.961	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.034	0.966	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.033	0.967	0.000
I72.4 Aneurysm of artery of lower extremity	0.031	0.969	0.000
I72 Other aneurysm	0.031	0.969	0.000
I72.8 Aneurysm of other specified arteries	0.029	0.971	0.000
K62 Other diseases of anus and rectum	0.028	0.972	0.000
I72.0 Aneurysm of carotid artery	0.028	0.972	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.027	0.973	0.000
I72.3 Aneurysm of iliac artery	0.026	0.973	0.000
I72.9 Aneurysm of unspecified site	0.026	0.974	0.000
I85.9 Oesophageal varices without bleeding	0.026	0.974	0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.025	0.975	0.000
I72.1 Aneurysm of artery of upper extremity	0.025	0.975	0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.025	0.975	0.000
I72.2 Aneurysm of renal artery	0.024	0.976	0.000
K62.6 Ulcer of anus and rectum	0.024	0.976	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.976	0.024
K62.0 Anal polyp	0.023	0.977	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.023	0.977	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.023	0.977	0.000
K62.2 Anal prolapse	0.023	0.977	0.000
K62.9 Disease of anus and rectum, unspecified	0.022	0.978	0.000
C15.9 Oesophagus, unspecified	0.020	0.980	0.001
I85 Oesophageal varices	0.019	0.981	0.000
I85.0 Oesophageal varices with bleeding	0.018	0.982	0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.018	0.982	0.000
K62.4 Stenosis of anus and rectum	0.017	0.983	0.000
K62.3 Rectal prolapse	0.016	0.984	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.015	0.985	0.000
K62.7 Radiation proctitis	0.011	0.989	0.000
C15.5 Lower third of oesophagus	0.009	0.989	0.002
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.990	0.010
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.991	0.009
O20 Haemorrhage in early pregnancy	0.000	0.991	0.009
M81.98 Osteoporosis, unspecified (Other)	0.008	0.992	0.000
Z09.0 Follow-up examination after surgery for other conditions	0.008	0.992	0.000
W44.0 Home	0.000	0.994	0.006
M81.9 Osteoporosis, unspecified	0.006	0.994	0.000
I49.9 Cardiac arrhythmia, unspecified	0.006	0.994	0.000
O20.8 Other haemorrhage in early pregnancy	0.000	0.994	0.006
Z12 Special screening examination for neoplasms	0.006	0.994	0.000
H66.9 Otitis media, unspecified	0.006	0.994	0.000
O20.0 Threatened abortion	0.000	0.995	0.005
D37.4 Colon	0.005	0.995	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.005	0.995	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M81 Osteoporosis without pathological fracture	0.005	0.995	0.000
Z12.6 Special screening examination for neoplasm of bladder	0.005	0.995	0.000
I46.9 Cardiac arrest, unspecified	0.005	0.995	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.005	0.995	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.005	0.995	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.005	0.995	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.005	0.995	0.000
M82.1 Osteoporosis in endocrine disorders	0.005	0.995	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.004	0.995	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.004	0.995	0.000
Z12.2 Special screening examination for neoplasm of respiratory organs	0.004	0.996	0.000
Z99.8 Dependence on other enabling machines and devices	0.000	0.996	0.004
I60.9 Subarachnoid haemorrhage, unspecified	0.004	0.996	0.000
M82 Osteoporosis in diseases classified elsewhere	0.004	0.996	0.000
M81.4 Drug-induced osteoporosis	0.004	0.996	0.000
M47.86 Other spondylosis (Lumbar region)	0.004	0.996	0.000
M81.0 Postmenopausal osteoporosis	0.004	0.996	0.000
M80-M85 Disorders of bone density and structure	0.004	0.996	0.000
S52.6 Fracture of lower end of both ulna and radius	0.000	0.996	0.004
Z12.3 Special screening examination for neoplasm of breast	0.004	0.996	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.004	0.996	0.000
M81.8 Other osteoporosis	0.004	0.996	0.000
M81.6 Localised osteoporosis [Lequesne]	0.004	0.996	0.000
M81.5 Idiopathic osteoporosis	0.004	0.996	0.000
M81.1 Postoophorectomy osteoporosis	0.004	0.996	0.000
H20.9 Iridocyclitis, unspecified	0.000	0.996	0.004
Z12.5 Special screening examination for neoplasm of prostate	0.004	0.996	0.000
Z12.0 Special screening examination for neoplasm of stomach	0.004	0.996	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.004	0.996	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.004	0.996	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.004	0.996	0.000
M81.2 Osteoporosis of disuse	0.004	0.996	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.004	0.996	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.004	0.996	0.000
M85 Other disorders of bone density and structure	0.004	0.996	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.003	0.996	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.003	0.996	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.003	0.996	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.003	0.996	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.003	0.996	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.003	0.996	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.003	0.996	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.003	0.996	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.004	0.996	0.000
I60 Subarachnoid haemorrhage	0.004	0.996	0.000
M80 Osteoporosis with pathological fracture	0.004	0.996	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.003	0.997	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.003	0.997	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.003	0.997	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.003	0.997	0.000
M81.48 Drug-induced osteoporosis (Other)	0.003	0.997	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.003	0.997	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.003	0.997	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.003	0.997	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.003	0.997	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.003	0.997	0.000
M83 Adult osteomalacia	0.003	0.997	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.003	0.997	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.003	0.997	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.003	0.997	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.003	0.997	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.003	0.997	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.003	0.997	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.003	0.997	0.000
Z89.6 Acquired absence of leg above knee	0.003	0.997	0.000
M84.02 Malunion of fracture (Upper arm)	0.003	0.997	0.000
Z89.5 Acquired absence of leg at or below knee	0.003	0.997	0.000
K63 Other diseases of intestine	0.003	0.997	0.000
M84 Disorders of continuity of bone	0.003	0.997	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.003	0.997	0.000
Z12.9 Special screening examination for neoplasm, unspecified	0.003	0.997	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.000	0.997	0.003
M84.0 Malunion of fracture	0.003	0.997	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.003	0.997	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.003	0.997	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.003	0.997	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.003	0.997	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.003	0.997	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.58 Idiopathic osteoporosis (Other)	0.003	0.997	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.003	0.997	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.003	0.997	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.003	0.997	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.003	0.997	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.003	0.997	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.003	0.997	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.003	0.997	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.003	0.997	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.003	0.997	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.003	0.997	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.003	0.997	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.003	0.997	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.003	0.997	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.003	0.997	0.000
M81.89 Other osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.88 Other osteoporosis (Other)	0.003	0.997	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.86 Other osteoporosis (Lower leg)	0.003	0.997	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.84 Other osteoporosis (Hand)	0.003	0.997	0.000
M81.83 Other osteoporosis (Forearm)	0.003	0.997	0.000
M81.82 Other osteoporosis (Upper arm)	0.003	0.997	0.000
M81.81 Other osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.80 Other osteoporosis (Multiple sites)	0.003	0.997	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.003	0.997	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.997	0.003
M70.22 Olecranon bursitis-Upper arm	0.000	0.997	0.003
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
M85.8 Other specified disorders of bone density and structure	0.003	0.997	0.000
Z89 Acquired absence of limb	0.003	0.997	0.000
K63.9 Disease of intestine, unspecified	0.003	0.997	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.003	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.003	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.003	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.003	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.003	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.003	0.997	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.000	0.997	0.003
M81.29 Osteoporosis of disuse (Site unspecified)	0.003	0.997	0.000
M81.28 Osteoporosis of disuse (Other)	0.003	0.997	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.003	0.997	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.003	0.997	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.003	0.997	0.000
M81.24 Osteoporosis of disuse (Hand)	0.003	0.997	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.003	0.997	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.003	0.997	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.003	0.997	0.000
M85.2 Hyperostosis of skull	0.003	0.997	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.003	0.997	0.000
M85.4 Solitary bone cyst	0.003	0.997	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.003	0.997	0.000
Z89.4 Acquired absence of foot and ankle	0.003	0.997	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.003	0.997	0.000
M84.8 Other disorders of continuity of bone	0.003	0.997	0.000
H20 Iridocyclitis	0.000	0.997	0.003
M85.5 Aneurysmal bone cyst	0.003	0.997	0.000
M85.3 Osteitis condensans	0.003	0.997	0.000
M85.1 Skeletal fluorosis	0.003	0.997	0.000
Z96.0 Presence of urogenital implants	0.003	0.997	0.000
C84.4 Peripheral T-cell lymphoma	0.003	0.997	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.003	0.997	0.000
Z12.8 Special screening examination for neoplasm of other sites	0.003	0.997	0.000
Z98.0 Intestinal bypass and anastomosis status	0.003	0.997	0.000
M76.67 Achilles tendinitis (Ankle and foot)	0.003	0.997	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.003	0.997	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.003	0.997	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.003	0.997	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.003	0.997	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.003	0.997	0.000
M83.8 Other adult osteomalacia	0.003	0.997	0.000
M85.0 Fibrous dysplasia (monostotic)	0.003	0.997	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
M81.40 Drug-induced osteoporosis (Multiple sites)	0.003	0.997	0.000
M83.3 Adult osteomalacia due to malnutrition	0.003	0.997	0.000
M85.9 Disorder of bone density and structure, unspecified	0.003	0.997	0.000
H20.8 Other iridocyclitis	0.000	0.997	0.003
M84.83 Other disorders of continuity of bone (Forearm)	0.003	0.997	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.002	0.997	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.002	0.997	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.002	0.997	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.002	0.997	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.002	0.997	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.002	0.997	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.002	0.997	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.002	0.997	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.002	0.997	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.002	0.997	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.002	0.997	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.002	0.997	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.002	0.997	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.002	0.997	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.002	0.997	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.002	0.997	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.002	0.997	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.002	0.997	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.002	0.997	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.002	0.997	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.003	0.997	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.003	0.997	0.000
M83.9 Adult osteomalacia, unspecified	0.003	0.997	0.000
M83.5 Other drug-induced osteomalacia in adults	0.003	0.997	0.000
M83.4 Aluminum bone disease	0.003	0.997	0.000
M83.2 Adult osteomalacia due to malabsorption	0.003	0.997	0.000
M83.0 Puerperal osteomalacia	0.003	0.997	0.000
M84.2 Delayed union of fracture	0.003	0.997	0.000
M84.06 Malunion of fracture (Lower leg)	0.003	0.997	0.000
M85.6 Other cyst of bone	0.003	0.997	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.003	0.997	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.003	0.997	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.003	0.997	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.997	0.003
Z12.4 Special screening examination for neoplasm of cervix	0.002	0.997	0.000
W44 Foreign body entering into or through eye or natural orifice	0.000	0.997	0.003
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.997	0.003
M84.9 Disorder of continuity of bone, unspecified	0.003	0.997	0.000
M84.4 Pathological fracture, not elsewhere classified	0.003	0.997	0.000
O28 Abnormal findings on antenatal screening of mother	0.000	0.997	0.003
Z89.9 Acquired absence of limb, unspecified	0.003	0.997	0.000
M84.09 Malunion of fracture (Site unspecified)	0.002	0.997	0.000
M84.08 Malunion of fracture (Other)	0.002	0.997	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.997	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.003	0.997	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.997	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.003	0.997	0.000
M85.20 Hyperostosis of skull-Mult sites	0.002	0.997	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.000	0.997	0.003
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.997	0.003
M85.65 Other cyst of bone (Pelvic region and thigh)	0.002	0.997	0.000
M80.8 Other osteoporosis with pathological fracture	0.002	0.997	0.000
M83.1 Senile osteomalacia	0.002	0.997	0.000
S64.4 Injury of digital nerve of other finger	0.000	0.997	0.003
M80.9 Unspecified osteoporosis with pathological fracture	0.003	0.997	0.000
M84.01 Malunion of fracture (Shoulder region)	0.002	0.997	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.002	0.997	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.997	0.000
I60.8 Other subarachnoid haemorrhage	0.002	0.997	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.002	0.997	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.002	0.997	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.997	0.002
Z89.3 Acquired absence of both upper limbs [any level]	0.002	0.997	0.000
Z89.1 Acquired absence of hand and wrist	0.002	0.997	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.002	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.002	0.998	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.002	0.998	0.000
M76.66 Achilles tendinitis (Lower leg)	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.002	0.998	0.000
M85.29 Hyperostosis of skull-Site unspec	0.002	0.998	0.000
M85.28 Hyperostosis of skull-Other	0.002	0.998	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.002	0.998	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.002	0.998	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.002	0.998	0.000
M85.24 Hyperostosis of skull-Hand	0.002	0.998	0.000
M85.23 Hyperostosis of skull-Forearm	0.002	0.998	0.000
M85.22 Hyperostosis of skull-Upper arm	0.002	0.998	0.000
M85.21 Hyperostosis of skull-Shldr region	0.002	0.998	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.002	0.998	0.000
M85.48 Solitary bone cyst (Other)	0.002	0.998	0.000
M85.46 Solitary bone cyst (Lower leg)	0.002	0.998	0.000
M85.44 Solitary bone cyst (Hand)	0.002	0.998	0.000
M85.43 Solitary bone cyst (Forearm)	0.002	0.998	0.000
M85.42 Solitary bone cyst (Upper arm)	0.002	0.998	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.002	0.998	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.002	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.002	0.998	0.000
M83.80 Other adult osteomalacia (Multiple sites)	0.002	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
D35.1 Parathyroid gland	0.002	0.998	0.000
Z86.0 Personal history of other neoplasms	0.002	0.998	0.000
Z90.4 Acquired absence of other parts of digestive tract	0.002	0.998	0.000
O22 Venous complications in pregnancy	0.000	0.998	0.002
D63.8 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.002	0.998	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.002	0.998	0.000
M84.88 Other disorders of continuity of bone (Other)	0.002	0.998	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.002	0.998	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.002	0.998	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.002	0.998	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.002	0.998	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.002	0.998	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.002	0.998	0.000
H20.2 Lens-induced iridocyclitis	0.000	0.998	0.002
M85.19 Skeletal fluorosis (Site unspecified)	0.002	0.998	0.000
M85.18 Skeletal fluorosis (Other)	0.002	0.998	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.002	0.998	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.002	0.998	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.002	0.998	0.000
M85.14 Skeletal fluorosis (Hand)	0.002	0.998	0.000
M85.13 Skeletal fluorosis (Forearm)	0.002	0.998	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.002	0.998	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.002	0.998	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.002	0.998	0.000
M85.39 Osteitis condensans (Site unspecified)	0.002	0.998	0.000
M85.38 Osteitis condensans (Other)	0.002	0.998	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.002	0.998	0.000
M85.36 Osteitis condensans (Lower leg)	0.002	0.998	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.002	0.998	0.000
M85.34 Osteitis condensans (Hand)	0.002	0.998	0.000
M85.33 Osteitis condensans (Forearm)	0.002	0.998	0.000
M85.32 Osteitis condensans (Upper arm)	0.002	0.998	0.000
M85.31 Osteitis condensans (Shoulder region)	0.002	0.998	0.000
M85.30 Osteitis condensans (Multiple sites)	0.002	0.998	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.002	0.998	0.000
M85.58 Aneurysmal bone cyst (Other)	0.002	0.998	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.002	0.998	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.002	0.998	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.002	0.998	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.002	0.998	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.002	0.998	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.002	0.998	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.002	0.998	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.002	0.998	0.000
M76.6 Achilles tendinitis	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.002	0.998	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.002	0.998	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.002	0.998	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.002	0.998	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.002	0.998	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.002	0.998	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
R87.9 Unspecified abnormal finding	0.002	0.998	0.000
Z09.1 Follow-up examination after radiotherapy for other conditions	0.002	0.998	0.000
M83.89 Other adult osteomalacia (Site unspecified)	0.002	0.998	0.000
M83.88 Other adult osteomalacia (Other)	0.002	0.998	0.000
M83.87 Other adult osteomalacia (Ankle and foot)	0.002	0.998	0.000
M83.86 Other adult osteomalacia (Lower leg)	0.002	0.998	0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.002	0.998	0.000
M83.84 Other adult osteomalacia (Hand)	0.002	0.998	0.000
M83.83 Other adult osteomalacia (Forearm)	0.002	0.998	0.000
M83.82 Other adult osteomalacia (Upper arm)	0.002	0.998	0.000
M83.81 Other adult osteomalacia (Shoulder region)	0.002	0.998	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.002	0.998	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.002	0.998	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.002	0.998	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.002	0.998	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations