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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs200956
log Bayes Factor = 128.114
Chromosome 6   position 27,839,746  (GRCh37) Explore rs200956 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
N40 Hyperplasia of prostate
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
0.999 0.001 0.000
E16.2 Hypoglycaemia, unspecified
0.999 0.001 0.000
E10.3 With ophthalmic complications
0.998 0.002 0.000
E14 Unspecified diabetes mellitus
0.997 0.003 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.003 0.997
E27 Other disorders of adrenal gland
0.997 0.003 0.000
K40 Inguinal hernia
0.000 0.005 0.995
E27.1 Primary adrenocortical insufficiency
0.995 0.005 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.016 0.984
E14.3 With ophthalmic complications
0.984 0.016 0.000
K40-K46 Hernia
0.002 0.028 0.971
K44 Diaphragmatic hernia
0.001 0.037 0.963
E10.1 With ketoacidosis
0.962 0.038 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.042 0.958
E14.9 Without complications
0.950 0.050 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.949 0.051 0.000
E23 Hypofunction and other disorders of pituitary gland
0.946 0.054 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.936 0.064 0.000
K90 Intestinal malabsorption
0.886 0.085 0.029
E21.0 Primary hyperparathyroidism
0.914 0.086 0.000
E10.2 With renal complications
0.913 0.087 0.000
Chapter XI Diseases of the digestive system
0.160 0.127 0.713
K90-K93 Other diseases of the digestive system
0.170 0.128 0.702
E20 Hypoparathyroidism
0.855 0.145 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.843 0.157 0.000
E10.5 With peripheral circulatory complications
0.840 0.160 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.830 0.161 0.009
E16.0 Drug-induced hypoglycaemia without coma
0.833 0.167 0.000
E10.4 With neurological complications
0.833 0.167 0.000
K41 Femoral hernia
0.001 0.176 0.824
E23.0 Hypopituitarism
0.818 0.182 0.000
E10.0 With coma
0.815 0.185 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.812 0.188 0.000
E23.2 Diabetes insipidus
0.810 0.190 0.000
K50-K52 Noninfective enteritis and colitis
0.066 0.191 0.743
K51 Ulcerative colitis
0.001 0.200 0.799
E13 Other specified diabetes mellitus
0.799 0.201 0.000
E27.9 Disorder of adrenal gland, unspecified
0.797 0.203 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.205 0.795
E31 Polyglandular dysfunction
0.786 0.214 0.000
K46 Unspecified abdominal hernia
0.001 0.215 0.784
E27.3 Drug-induced adrenocortical insufficiency
0.785 0.215 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.218 0.782
E24 Cushing's syndrome
0.778 0.221 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.231 0.769
E29 Testicular dysfunction
0.768 0.232 0.000
E50-E64 Other nutritional deficiencies
0.765 0.235 0.000
E25 Adrenogenital disorders
0.764 0.236 0.000
E14.4 With neurological complications
0.761 0.239 0.000
K51.4 Pseudopolyposis of colon
0.000 0.243 0.757
E20.9 Hypoparathyroidism, unspecified
0.752 0.248 0.000
E27.2 Addisonian crisis
0.751 0.249 0.000
E14.5 With peripheral circulatory complications
0.747 0.253 0.000
E23.6 Other disorders of pituitary gland
0.747 0.253 0.000
E16.1 Other hypoglycaemia
0.743 0.257 0.000
E14.2 Withrenal complications
0.742 0.258 0.000
E10.6 With other specified complications
0.741 0.259 0.000
E14.6 With other specified complications
0.735 0.265 0.000
E23.7 Disorder of pituitary gland, unspecified
0.730 0.270 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
K92 Other diseases of digestive system
0.003 0.283 0.714
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.283 0.000
E16.3 Increased secretion of glucagon
0.716 0.283 0.000
E21.3 Hyperparathyroidism, unspecified
0.716 0.284 0.000
E14.7 With multiple complications
0.715 0.285 0.000
E14.0 With coma
0.715 0.285 0.000
E27.5 Adrenomedullary hyperfunction
0.715 0.285 0.000
E27.0 Other adrenocortical overactivity
0.715 0.285 0.000
E14.1 With ketoacidosis
0.714 0.286 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.287 0.713
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.287 0.713
E10.8 With unspecified complications
0.708 0.292 0.000
K92.0 Haematemesis
0.000 0.292 0.708
E11 Non-insulin-dependent diabetes mellitus
0.706 0.294 0.000
E06 Thyroiditis
0.704 0.295 0.000
N40-N51 Diseases of male genital organs
0.000 0.297 0.703
E07 Other disorders of thyroid
0.701 0.299 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.308 0.692
K44.1 Diaphragmatic hernia with gangrene
0.001 0.309 0.690
N42 Other disorders of prostate
0.000 0.315 0.685
E21.5 Disorder of parathyroid gland, unspecified
0.680 0.320 0.000
E21.4 Other specified disorders of parathyroid gland
0.680 0.320 0.000
E21.2 Other hyperparathyroidism
0.680 0.320 0.000
K90.9 Intestinal malabsorption, unspecified
0.667 0.320 0.013
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.678 0.322 0.000
E23.1 Drug-induced hypopituitarism
0.678 0.322 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.325 0.675
E24.2 Drug-induced Cushing's syndrome
0.660 0.339 0.000
K35-K38 Diseases of appendix
0.126 0.341 0.533
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.341 0.658
K90.3 Pancreatic steatorrhoea
0.635 0.344 0.021
K90.2 Blind loop syndrome, not elsewhere classified
0.635 0.344 0.021
K90.1 Tropical sprue
0.635 0.344 0.021
N42.8 Other specified disorders of prostate
0.000 0.347 0.653
E11.3 With ophthalmic complications
0.652 0.348 0.000
N41 Inflammatory diseases of prostate
0.000 0.350 0.650
K92.1 Melaena
0.000 0.351 0.649
K92.9 Disease of digestive system, unspecified
0.001 0.355 0.645
E14.8 With unspecified complications
0.644 0.355 0.000
K50 Crohn's disease [regional enteritis]
0.003 0.357 0.640
E31.0 Autoimmune polyglandular failure
0.632 0.368 0.000
E11.5 With peripheral circulatory complications
0.629 0.371 0.000
E13.3 With ophthalmic complications
0.628 0.372 0.000
E05.8 Other thyrotoxicosis
0.625 0.375 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.122 0.375 0.503
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.624 0.376 0.000
E03.8 Other specified hypothyroidism
0.621 0.379 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.620 0.380 0.000
E53 Deficiency of other B group vitamins
0.619 0.381 0.000
K90.8 Other intestinal malabsorption
0.599 0.381 0.021
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.385 0.614
E20.8 Other hypoparathyroidism
0.613 0.387 0.000
E20.1 Pseudohypoparathyroidism
0.613 0.387 0.000
E20.0 Idiopathic hypoparathyroidism
0.613 0.387 0.000
N41.0 Acute prostatitis
0.000 0.387 0.613
E13.9 Without complications
0.608 0.392 0.000
N45 Orchitis and epididymitis
0.000 0.394 0.606
E11.6 With other specified complications
0.605 0.395 0.000
E29.1 Testicular hypofunction
0.602 0.397 0.000
E24.0 Pituitary-dependent Cushing's disease
0.600 0.400 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.594 0.406 0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.001 0.409 0.591
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.001 0.409 0.591
K41.1 Bilateral femoral hernia, with gangrene
0.001 0.409 0.591
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.001 0.409 0.591
E61 Deficiency of other nutrient elements
0.590 0.410 0.000
E40-E46 Malnutrition
0.589 0.411 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.418 0.582
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.421 0.578
E13.8 With unspecified complications
0.573 0.427 0.000
E13.7 With multiple complications
0.573 0.427 0.000
E13.6 With other specified complications
0.573 0.427 0.000
E13.5 With peripheral circulatory complications
0.573 0.427 0.000
E13.4 With neurological complications
0.573 0.427 0.000
E13.2 With renal complications
0.573 0.427 0.000
E13.1 With ketoacidosis
0.573 0.427 0.000
E13.0 With coma
0.573 0.427 0.000
E26 Hyperaldosteronism
0.564 0.435 0.000
E34 Other endocrine disorders
0.565 0.435 0.000
E31.9 Polyglandular dysfunction, unspecified
0.563 0.437 0.000
E31.8 Other polyglandular dysfunction
0.563 0.437 0.000
E31.1 Polyglandular hyperfunction
0.563 0.437 0.000
K46.1 Unspecified abdominal hernia with gangrene
0.001 0.437 0.562
E24.8 Other Cushing's syndrome
0.558 0.442 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.558 0.442 0.000
E24.3 Ectopic ACTH syndrome
0.558 0.442 0.000
E24.1 Nelson's syndrome
0.558 0.442 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.442 0.558
N42.0 Calculus of prostate
0.000 0.442 0.558
E29.9 Testicular dysfunction, unspecified
0.551 0.449 0.000
E29.8 Other testicular dysfunction
0.551 0.449 0.000
E29.0 Testicular hyperfunction
0.551 0.449 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.001 0.450 0.549
E64 Sequelae of malnutrition and other nutritional deficiencies
0.549 0.451 0.000
E63 Other nutritional deficiencies
0.549 0.451 0.000
E56 Other vitamin deficiencies
0.549 0.451 0.000
E50 Vitamin A deficiency
0.549 0.451 0.000
E60 Dietary zinc deficiency
0.549 0.451 0.000
E59 Dietary selenium deficiency
0.549 0.451 0.000
E58 Dietary calcium deficiency
0.549 0.451 0.000
E54 Ascorbic acid deficiency
0.549 0.451 0.000
E52 Niacin deficiency [pellagra]
0.549 0.451 0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.001 0.452 0.547
E25.9 Adrenogenital disorder, unspecified
0.547 0.452 0.000
E25.8 Other adrenogenital disorders
0.547 0.452 0.000
K38 Other diseases of appendix
0.063 0.453 0.484
E51 Thiamine deficiency
0.547 0.453 0.000
E11.0 With coma
0.539 0.461 0.000
N46 Male infertility
0.000 0.462 0.538
E07.8 Other specified disorders of thyroid
0.536 0.464 0.000
K50.1 Crohn's disease of large intestine
0.001 0.474 0.526
E06.5 Other chronic thyroiditis
0.525 0.475 0.000
E53.8 Deficiency of other specified B group vitamins
0.524 0.476 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E30.9 Disorder of puberty, unspecified
0.514 0.486 0.000
E30.8 Other disorders of puberty
0.514 0.486 0.000
E30.1 Precocious puberty
0.514 0.486 0.000
E30.0 Delayed puberty
0.514 0.486 0.000
E32.9 Disease of thymus, unspecified
0.514 0.486 0.000
E32.8 Other diseases of thymus
0.514 0.486 0.000
E32.1 Abscess of thymus
0.514 0.486 0.000
E32.0 Persistent hyperplasia of thymus
0.514 0.486 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.514 0.486 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.514 0.486 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.514 0.486 0.000
E22 Hyperfunction of pituitary gland
0.511 0.489 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.492 0.508
E11.7 With multiple complications
0.506 0.494 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.494 0.506
E06.4 Drug-induced thyroiditis
0.505 0.495 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.505 0.495 0.000
E06.1 Subacute thyroiditis
0.505 0.495 0.000
E06.0 Acute thyroiditis
0.505 0.495 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.496 0.504
N44 Torsion of testis
0.000 0.496 0.504
K50.8 Other Crohn's disease
0.001 0.497 0.502
E07.1 Dyshormogenetic goitre
0.502 0.497 0.000
E07.0 Hypersecretion of calcitonin
0.502 0.497 0.000
K51.5 Mucosal proctocolitis
0.001 0.501 0.499
E06.3 Autoimmune thyroiditis
0.496 0.504 0.000
N42.3 Dysplasia of prostate
0.000 0.509 0.491
E28 Ovarian dysfunction
0.488 0.512 0.001
N42.2 Atrophy of prostate
0.000 0.515 0.485
K50.9 Crohn's disease, unspecified
0.000 0.519 0.481
K37 Unspecified appendicitis
0.020 0.520 0.460
E06.9 Thyroiditis, unspecified
0.480 0.520 0.000
N41.1 Chronic prostatitis
0.000 0.522 0.478
N39 Other disorders of urinary system
0.000 0.522 0.478
K38.8 Other specified diseases of appendix
0.014 0.524 0.462
N42.9 Disorder of prostate, unspecified
0.000 0.529 0.471
K42 Umbilical hernia
0.000 0.531 0.468
N39.8 Other specified disorders of urinary system
0.000 0.532 0.468
N39.9 Disorder of urinary system, unspecified
0.000 0.532 0.468
K92.8 Other specified diseases of digestive system
0.002 0.533 0.465
N30-N39 Other diseases of urinary system
0.000 0.533 0.467
N32.0 Bladder-neck obstruction
0.000 0.534 0.466
N41.3 Prostatocystitis
0.000 0.534 0.466
N41.2 Abscess of prostate
0.000 0.534 0.466
E61.1 Iron deficiency
0.465 0.535 0.000
K50.0 Crohn's disease of small intestine
0.001 0.536 0.463
N32 Other disorders of bladder
0.000 0.536 0.464
E55 Vitamin D deficiency
0.460 0.540 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.087 0.552 0.361
K93.1 Megacolon in Chagas' disease
0.087 0.552 0.361
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.087 0.552 0.361
N36 Other disorders of urethra
0.000 0.555 0.445
E53.1 Pyridoxine deficiency
0.444 0.556 0.000
E53.0 Riboflavin deficiency
0.444 0.556 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.556 0.444
K92.2 Gastro-intestinal haemorrhage, unspecified
0.000 0.556 0.444
E07.9 Disorder of thyroid, unspecified
0.443 0.557 0.000
E22.1 Hyperprolactinaemia
0.430 0.570 0.000
N36.2 Urethral caruncle
0.000 0.572 0.428
E11.1 With ketoacidosis
0.428 0.572 0.000
E53.9 Vitamin B deficiency, unspecified
0.428 0.572 0.000
E61.9 Deficiency of nutrient element, unspecified
0.423 0.577 0.000
E61.8 Deficiency of other specified nutrient elements
0.423 0.577 0.000
E61.7 Deficiency of multiple nutrient elements
0.423 0.577 0.000
E61.6 Vanadium deficiency
0.423 0.577 0.000
E61.5 Molybdenum deficiency
0.423 0.577 0.000
E61.4 Chromium deficiency
0.423 0.577 0.000
E61.3 Manganese deficiency
0.423 0.577 0.000
E61.2 Magnesium deficiency
0.423 0.577 0.000
E61.0 Copper deficiency
0.423 0.577 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.422 0.577 0.000
E45 Retarded development following protein-energy malnutrition
0.422 0.577 0.000
E43 Unspecified severe protein-energy malnutrition
0.422 0.577 0.000
E42 Marasmic kwashiorkor
0.422 0.577 0.000
E41 Nutritional marasmus
0.422 0.577 0.000
E40 Kwashiorkor
0.422 0.577 0.000
M20.1 Hallux valgus (acquired)
0.000 0.584 0.416
K45 Other abdominal hernia
0.003 0.586 0.412
E24.9 Cushing's syndrome, unspecified
0.414 0.586 0.000
N39.0 Urinary tract infection, site not specified
0.000 0.589 0.411
N39.3 Stress incontinence
0.000 0.590 0.410
E26.9 Hyperaldosteronism, unspecified
0.405 0.595 0.000
E26.8 Other hyperaldosteronism
0.405 0.595 0.000
E26.1 Secondary hyperaldosteronism
0.405 0.595 0.000
E34.5 Androgen resistance syndrome
0.405 0.595 0.000
E34.4 Constitutional tall stature
0.405 0.595 0.000
E34.3 Short stature, not elsewhere classified
0.405 0.595 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.405 0.595 0.000
E34.1 Other hypersecretion of intestinal hormones
0.405 0.595 0.000
K51.8 Other ulcerative colitis
0.001 0.600 0.400
E34.9 Endocrine disorder, unspecified
0.397 0.603 0.000
E50.9 Vitamin A deficiency, unspecified
0.393 0.606 0.000
E50.8 Other manifestations of vitamin A deficiency
0.393 0.606 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.393 0.606 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.393 0.606 0.000
E50.5 Vitamin A deficiency with night blindness
0.393 0.606 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.393 0.606 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.393 0.606 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.393 0.606 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.393 0.606 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.393 0.606 0.000
E56.9 Vitamin deficiency, unspecified
0.393 0.606 0.000
E56.8 Deficiency of other vitamins
0.393 0.606 0.000
E56.1 Deficiency of vitamin K
0.393 0.606 0.000
E56.0 Deficiency of vitamin E
0.393 0.606 0.000
E63.9 Nutritional deficiency, unspecified
0.393 0.606 0.000
E63.8 Other specified nutritional deficiencies
0.393 0.606 0.000
E63.1 Imbalance of constituents of food intake
0.393 0.606 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.393 0.606 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.393 0.606 0.000
E64.8 Sequelae of other nutritional deficiencies
0.393 0.606 0.000
E64.3 Sequelae of rickets
0.393 0.606 0.000
E64.2 Sequelae of vitamin C deficiency
0.393 0.606 0.000
E64.1 Sequelae of vitamin A deficiency
0.393 0.606 0.000
E64.0 Sequelae of protein-energy malnutrition
0.393 0.606 0.000
K38.3 Fistula of appendix
0.045 0.607 0.347
K38.2 Diverticulum of appendix
0.045 0.607 0.347
K38.0 Hyperplasia of appendix
0.045 0.607 0.347
E51.9 Thiamine deficiency, unspecified
0.392 0.608 0.000
E51.8 Other manifestations of thiamine deficiency
0.392 0.608 0.000
E51.1 Beriberi
0.392 0.608 0.000
E51.2 Wernicke's encephalopathy
0.390 0.610 0.000
N41.8 Other inflammatory diseases of prostate
0.000 0.613 0.387
K36 Other appendicitis
0.095 0.613 0.291
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.616 0.384
K38.1 Appendicular concretions
0.040 0.617 0.344
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.618 0.382
N34 Urethritis and urethral syndrome
0.000 0.620 0.380
K65-K67 Diseases of peritoneum
0.063 0.621 0.316
N32.8 Other specified disorders of bladder
0.000 0.624 0.376
N32.1 Vesicointestinal fistula
0.000 0.626 0.374
E34.8 Other specified endocrine disorders
0.371 0.628 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.366 0.633 0.000
E22.8 Other hyperfunction of pituitary gland
0.366 0.633 0.000
E11.9 Without complications
0.362 0.638 0.000
E27.8 Other specified disorders of adrenal gland
0.361 0.638 0.001
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.638 0.362
N36.3 Prolapsed urethral mucosa
0.000 0.638 0.362
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.638 0.361
N51.2 Balanitis in diseases classified elsewhere
0.000 0.638 0.361
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.638 0.361
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.638 0.361
E28.9 Ovarian dysfunction, unspecified
0.350 0.650 0.001
E28.8 Other ovarian dysfunction
0.350 0.650 0.001
E28.1 Androgen excess
0.350 0.650 0.001
E28.0 Oestrogen excess
0.350 0.650 0.001
E11.8 With unspecified complications
0.350 0.650 0.000
N36.0 Urethral fistula
0.000 0.653 0.347
E28.3 Primary ovarian failure
0.347 0.653 0.000
E11.2 With renal complications
0.347 0.653 0.000
N39.2 Orthostatic proteinuria, unspecified
0.000 0.657 0.342
Chapter XIV Diseases of the genitourinary system
0.000 0.660 0.340
K42.1 Umbilical hernia with gangrene
0.000 0.664 0.336
K42.0 Umbilical hernia with obstruction, without gangrene
0.000 0.665 0.335
N37 Urethral disorders in diseases classified elsewhere
0.000 0.665 0.335
N33 Bladder disorders in diseases classified elsewhere
0.000 0.665 0.335
N32.4 Rupture of bladder, nontraumatic
0.000 0.667 0.332
N32.2 Vesical fistula, not elsewhere classified
0.000 0.667 0.332
K38.9 Disease of appendix, unspecified
0.050 0.669 0.280
E55.0 Rickets, active
0.330 0.670 0.000
N36.1 Urethral diverticulum
0.000 0.671 0.329
N34.2 Other urethritis
0.000 0.672 0.328
N32.3 Diverticulum of bladder
0.000 0.674 0.326
N36.9 Urethral disorder, unspecified
0.000 0.675 0.325
E34.0 Carcinoid syndrome
0.318 0.681 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.682 0.318
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.682 0.318
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.682 0.318
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.682 0.318
E65-E68 Obesity and other hyperalimentation
0.308 0.691 0.000
M20 Acquired deformities of fingers and toes
0.002 0.692 0.305
E44.1 Mild protein-energy malnutrition
0.303 0.697 0.000
E44.0 Moderate protein-energy malnutrition
0.303 0.697 0.000
K45.1 Other specified abdominal hernia with gangrene
0.002 0.703 0.295
N39.1 Persistent proteinuria, unspecified
0.000 0.705 0.294
E46 Unspecified protein-energy malnutrition
0.294 0.705 0.000
N20-N23 Urolithiasis
0.000 0.709 0.291
M20.4 Other hammer toe(s) (acquired)
0.000 0.710 0.290
N34.0 Urethral abscess
0.000 0.728 0.272
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.045 0.728 0.227
M20.5 Other deformities of toe(s) (acquired)
0.000 0.730 0.270
N34.3 Urethral syndrome, unspecified
0.000 0.730 0.270
N43 Hydrocele and spermatocele
0.000 0.733 0.267
N23 Unspecified renal colic
0.000 0.737 0.263
N49.2 Inflammatory disorders of scrotum
0.000 0.742 0.258
N34.1 Nonspecific urethritis
0.000 0.746 0.254
E26.0 Primary hyperaldosteronism
0.252 0.747 0.001
K70-K77 Diseases of liver
0.180 0.748 0.072
M20.6 Acquired deformity of toe(s), unspecified
0.001 0.750 0.249
H36.0 Diabetic retinopathy
0.241 0.759 0.000
E55.9 Vitamin D deficiency, unspecified
0.241 0.759 0.000
N33.8 Bladder disorders in other diseases classified elsewhere
0.000 0.760 0.240
N33.0 Tuberculous cystitis
0.000 0.760 0.240
N37.8 Other urethral disorders in diseases classified elsewhere
0.000 0.760 0.240
N37.0 Urethritis in diseases classified elsewhere
0.000 0.760 0.240
E83 Disorders of mineral metabolism
0.040 0.762 0.197
N20 Calculus of kidney and ureter
0.000 0.763 0.237
K75.4 Autoimmune hepatitis
0.236 0.763 0.001
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.002 0.765 0.233
K75 Other inflammatory liver diseases
0.227 0.766 0.007
H36 Retinal disorders in diseases classified elsewhere
0.228 0.772 0.000
N35 Urethral stricture
0.000 0.773 0.226
K43 Ventral hernia
0.001 0.775 0.224
N20.0 Calculus of kidney
0.000 0.777 0.223
E67 Other hyperalimentation
0.221 0.778 0.000
E68 Sequelae of hyperalimentation
0.221 0.778 0.000
K75.8 Other specified inflammatory liver diseases
0.220 0.779 0.001
H30-H36 Disorders of choroid and retina
0.219 0.781 0.000
E22.0 Acromegaly and pituitary gigantism
0.218 0.781 0.001
H34 Retinal vascular occlusions
0.211 0.789 0.000
K66 Other disorders of peritoneum
0.014 0.789 0.197
N22 Calculus of urinary tract in diseases classified elsewhere
0.000 0.791 0.208
N20.1 Calculus of ureter
0.000 0.792 0.208
K52 Other non-infective gastro-enteritis and colitis
0.061 0.792 0.147
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.208 0.792 0.000
D80-D89 Certain disorders involving the immune mechanism
0.207 0.793 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.203 0.796 0.001
D50-D53 Nutritional anaemias
0.203 0.797 0.000
D50 Iron deficiency anaemia
0.203 0.797 0.000
D86 Sarcoidosis
0.203 0.797 0.000
N48 Other disorders of penis
0.000 0.797 0.203
M35.0 Sicca syndrome [Sjogren]
0.202 0.798 0.000
N99-N99 Other disorders of the genitourinary system
0.000 0.798 0.202
H34.8 Other retinal vascular occlusions
0.201 0.799 0.000
M20.0 Deformity of finger(s)
0.001 0.800 0.199
# Top node
0.197 0.803 0.000
Chapter VII Diseases of the eye and adnexa
0.197 0.803 0.000
D50.9 Iron deficiency anaemia, unspecified
0.197 0.803 0.000
D86.9 Sarcoidosis, unspecified
0.196 0.804 0.000
D64.9 Anaemia, unspecified
0.196 0.804 0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere
0.033 0.805 0.163
K67.3 Tuberculous peritonitis
0.033 0.805 0.163
K67.2 Syphilitic peritonitis
0.033 0.805 0.163
K67.1 Gonococcal peritonitis
0.033 0.805 0.163
K67.0 Chlamydial peritonitis
0.033 0.805 0.163
D60-D64 Aplastic and other anaemias
0.193 0.807 0.000
D64 Other anaemias
0.192 0.808 0.000
D50.8 Other iron deficiency anaemias
0.192 0.808 0.000
N43.2 Other hydrocele
0.000 0.808 0.192
N43.1 Infected hydrocele
0.000 0.808 0.192
N43.0 Encysted hydrocele
0.000 0.808 0.192
K73 Chronic hepatitis, not elsewhere classified
0.159 0.810 0.031
Chapter XII Diseases of the skin and subcutaneous tissue
0.189 0.811 0.000
E83.3 Disorders of phosphorus metabolism
0.013 0.815 0.172
K71 Toxic liver disease
0.135 0.816 0.048
L80-L99 Other disorders of the skin and subcutaneous tissue
0.182 0.818 0.000
K72 Hepatic failure, not elsewhere classified
0.158 0.819 0.023
K77 Liver disorders in diseases classified elsewhere
0.129 0.819 0.052
L50-L54 Urticaria and erythema
0.180 0.820 0.000
K75.9 Inflammatory liver disease, unspecified
0.177 0.820 0.003
M20.3 Other deformity of hallux (acquired)
0.001 0.820 0.179
N48.1 Balanoposthitis
0.000 0.821 0.179
L93 Lupus erythematosus
0.177 0.823 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.177 0.823 0.000
N36.8 Other specified disorders of urethra
0.000 0.824 0.176
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.176 0.824 0.000
K66.9 Disorder of peritoneum, unspecified
0.007 0.824 0.169
M35 Other systemic involvement of connective tissue
0.175 0.825 0.000
L10-L14 Bullous disorders
0.174 0.826 0.000
N50 Other disorders of male genital organs
0.000 0.826 0.174
K66.1 Haemoperitoneum
0.007 0.827 0.167
H34.2 Other retinal artery occlusions
0.171 0.829 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.029 0.829 0.142
E83.8 Other disorders of mineral metabolism
0.029 0.829 0.142
E83.2 Disorders of zinc metabolism
0.029 0.829 0.142
E83.0 Disorders of copper metabolism
0.029 0.829 0.142
H46-H48 Disorders of optic nerve and visual pathways
0.170 0.830 0.000
L93.0 Discoid lupus erythematosus
0.170 0.830 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.163 0.832 0.005
K75.2 Nonspecific reactive hepatitis
0.163 0.832 0.005
K75.1 Phlebitis of portal vein
0.163 0.832 0.005
L92 Granulomatous disorders of skin and subcutaneous tissue
0.168 0.832 0.000
Q50-Q56 Congenital malformations of genital organs
0.166 0.834 0.000
N35.8 Other urethral stricture
0.000 0.835 0.165
H34.1 Central retinal artery occlusion
0.165 0.835 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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