TreeWAS – Variant ID: rs200973

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.000	1.000
E03 Other hypothyroidism	0.999	0.001	0.000
E03.9 Hypothyroidism, unspecified	0.999	0.001	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.997	0.003	0.000
E16 Other disorders of pancreatic internal secretion	0.996	0.004	0.000
E16.2 Hypoglycaemia, unspecified	0.993	0.007	0.000
N40 Hyperplasia of prostate	0.000	0.008	0.992
K40 Inguinal hernia	0.000	0.011	0.989
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.013	0.987
E05.0 Thyrotoxicosis with diffuse goitre	0.979	0.021	0.000
N40-N51 Diseases of male genital organs	0.000	0.023	0.977
N41 Inflammatory diseases of prostate	0.000	0.030	0.970
E10.3 With ophthalmic complications	0.965	0.035	0.000
N42 Other disorders of prostate	0.000	0.037	0.963
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.040	0.960
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.042	0.958
N42.8 Other specified disorders of prostate	0.000	0.068	0.932
N42.1 Congestion and haemorrhage of prostate	0.000	0.068	0.932
E20-E35 Disorders of other endocrine glands	0.914	0.086	0.000
E10.6 With other specified complications	0.907	0.093	0.000
E27 Other disorders of adrenal gland	0.892	0.108	0.000
E27.1 Primary adrenocortical insufficiency	0.882	0.118	0.000
E11 Non-insulin-dependent diabetes mellitus	0.873	0.127	0.000
E07 Other disorders of thyroid	0.867	0.133	0.000
E10.2 With renal complications	0.862	0.138	0.000
N46 Male infertility	0.000	0.145	0.855
E10.1 With ketoacidosis	0.848	0.152	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.842	0.158	0.000
E11.5 With peripheral circulatory complications	0.839	0.161	0.000
E23 Hypofunction and other disorders of pituitary gland	0.838	0.162	0.000
E11.3 With ophthalmic complications	0.832	0.168	0.000
N41.0 Acute prostatitis	0.000	0.181	0.819
E10.4 With neurological complications	0.819	0.181	0.000
N41.1 Chronic prostatitis	0.000	0.189	0.811
N45 Orchitis and epididymitis	0.000	0.192	0.808
K90 Intestinal malabsorption	0.782	0.212	0.006
E14 Unspecified diabetes mellitus	0.787	0.213	0.000
E50-E64 Other nutritional deficiencies	0.754	0.246	0.000
E23.2 Diabetes insipidus	0.751	0.249	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.750	0.250	0.000
N42.0 Calculus of prostate	0.000	0.252	0.748
E10.0 With coma	0.741	0.259	0.000
E16.1 Other hypoglycaemia	0.737	0.263	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.270	0.730
E27.4 Other and unspecified adrenocortical insufficiency	0.722	0.278	0.000
E07.9 Disorder of thyroid, unspecified	0.718	0.282	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E10.7 With multiple complications	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E03.5 Myxoedema coma	0.716	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.716	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.716	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.716	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.716	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.715	0.285	0.000
E13 Other specified diabetes mellitus	0.715	0.285	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.714	0.286	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.714	0.286	0.000
E16.4 Abnormal secretion of gastrin	0.714	0.286	0.000
E16.3 Increased secretion of glucagon	0.714	0.286	0.000
E07.8 Other specified disorders of thyroid	0.711	0.289	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.290	0.710
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.000	0.291	0.709
K40.1 Bilateral inguinal hernia, with gangrene	0.000	0.291	0.709
N51 Disorders of male genital organs in diseases classified elsewhere	0.000	0.299	0.701
N44 Torsion of testis	0.000	0.299	0.701
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.000	0.301	0.699
N41.3 Prostatocystitis	0.000	0.304	0.696
N41.2 Abscess of prostate	0.000	0.304	0.696
E27.3 Drug-induced adrenocortical insufficiency	0.695	0.305	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.694	0.306	0.000
E31 Polyglandular dysfunction	0.692	0.308	0.000
N42.3 Dysplasia of prostate	0.000	0.310	0.690
E20 Hypoparathyroidism	0.680	0.320	0.000
E10.5 With peripheral circulatory complications	0.680	0.320	0.000
E11.0 With coma	0.679	0.321	0.000
E03.8 Other specified hypothyroidism	0.672	0.328	0.000
E24 Cushing's syndrome	0.671	0.329	0.000
E10.8 With unspecified complications	0.666	0.334	0.000
E06 Thyroiditis	0.664	0.336	0.000
K90.9 Intestinal malabsorption, unspecified	0.662	0.336	0.002
E23.7 Disorder of pituitary gland, unspecified	0.659	0.341	0.000
E14.3 With ophthalmic complications	0.658	0.342	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.655	0.345	0.000
E32 Diseases of thymus	0.655	0.345	0.000
E30 Disorders of puberty, not elsewhere classified	0.655	0.345	0.000
E25 Adrenogenital disorders	0.655	0.345	0.000
E23.0 Hypopituitarism	0.652	0.348	0.000
E11.1 With ketoacidosis	0.641	0.359	0.000
E27.5 Adrenomedullary hyperfunction	0.639	0.361	0.000
E27.0 Other adrenocortical overactivity	0.639	0.361	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.634	0.363	0.003
E14.2 Withrenal complications	0.634	0.366	0.000
E05.8 Other thyrotoxicosis	0.626	0.373	0.000
E11.7 With multiple complications	0.626	0.374	0.000
E07.1 Dyshormogenetic goitre	0.622	0.378	0.000
E07.0 Hypersecretion of calcitonin	0.622	0.378	0.000
E27.2 Addisonian crisis	0.617	0.383	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.616	0.384	0.000
E27.9 Disorder of adrenal gland, unspecified	0.616	0.384	0.000
E53 Deficiency of other B group vitamins	0.612	0.388	0.000
N41.8 Other inflammatory diseases of prostate	0.000	0.390	0.610
E40-E46 Malnutrition	0.605	0.395	0.000
E14.4 With neurological complications	0.604	0.396	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.600	0.399	0.000
E23.1 Drug-induced hypopituitarism	0.600	0.399	0.000
E11.6 With other specified complications	0.596	0.404	0.000
K90.8 Other intestinal malabsorption	0.590	0.406	0.004
E23.6 Other disorders of pituitary gland	0.582	0.418	0.000
E29 Testicular dysfunction	0.580	0.420	0.000
E51 Thiamine deficiency	0.569	0.431	0.000
K90.3 Pancreatic steatorrhoea	0.561	0.435	0.004
K90.2 Blind loop syndrome, not elsewhere classified	0.561	0.435	0.004
K90.1 Tropical sprue	0.561	0.435	0.004
E14.7 With multiple complications	0.564	0.436	0.000
E14.5 With peripheral circulatory complications	0.564	0.436	0.000
E14.0 With coma	0.564	0.436	0.000
E14.6 With other specified complications	0.563	0.437	0.000
E14.1 With ketoacidosis	0.557	0.442	0.000
E11.8 With unspecified complications	0.554	0.446	0.000
E06.9 Thyroiditis, unspecified	0.548	0.452	0.000
E28 Ovarian dysfunction	0.544	0.456	0.000
E58 Dietary calcium deficiency	0.544	0.456	0.000
E26 Hyperaldosteronism	0.541	0.458	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.541	0.459	0.000
E63 Other nutritional deficiencies	0.541	0.459	0.000
E56 Other vitamin deficiencies	0.541	0.459	0.000
E50 Vitamin A deficiency	0.541	0.459	0.000
E60 Dietary zinc deficiency	0.541	0.459	0.000
E59 Dietary selenium deficiency	0.541	0.459	0.000
E54 Ascorbic acid deficiency	0.541	0.459	0.000
E52 Niacin deficiency [pellagra]	0.541	0.459	0.000
E61 Deficiency of other nutrient elements	0.536	0.464	0.000
E24.2 Drug-induced Cushing's syndrome	0.534	0.466	0.000
E31.0 Autoimmune polyglandular failure	0.532	0.468	0.000
E34 Other endocrine disorders	0.529	0.470	0.000
E14.8 With unspecified complications	0.526	0.474	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.000	0.476	0.524
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
E12.9 Without complications	0.514	0.486	0.000
E12.8 With unspecified complications	0.514	0.486	0.000
E12.7 With multiple complications	0.514	0.486	0.000
E12.6 With other specified complications	0.514	0.486	0.000
E12.5 With peripheral circulatory complications	0.514	0.486	0.000
E12.4 With neurological complications	0.514	0.486	0.000
E12.3 With ophthalmic complications	0.514	0.486	0.000
E12.2 With renal complications	0.514	0.486	0.000
E12.1 With ketoacidosis	0.514	0.486	0.000
E12.0 With coma	0.514	0.486	0.000
E13.8 With unspecified complications	0.512	0.487	0.000
E13.7 With multiple complications	0.512	0.487	0.000
E13.6 With other specified complications	0.512	0.487	0.000
E13.5 With peripheral circulatory complications	0.512	0.487	0.000
E13.4 With neurological complications	0.512	0.487	0.000
E13.3 With ophthalmic complications	0.512	0.487	0.000
E13.2 With renal complications	0.512	0.487	0.000
E13.1 With ketoacidosis	0.512	0.487	0.000
E13.0 With coma	0.512	0.487	0.000
N42.2 Atrophy of prostate	0.000	0.488	0.512
E20.9 Hypoparathyroidism, unspecified	0.512	0.488	0.000
D64.9 Anaemia, unspecified	0.511	0.489	0.000
E13.9 Without complications	0.510	0.490	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.000	0.491	0.509
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.000	0.491	0.509
N49.0 Inflammatory disorders of seminal vesicle	0.000	0.491	0.509
E53.8 Deficiency of other specified B group vitamins	0.505	0.495	0.000
N49.2 Inflammatory disorders of scrotum	0.000	0.496	0.504
N51.8 Other disorders of male genital organs in diseases classified elsewhere	0.000	0.497	0.502
N51.2 Balanitis in diseases classified elsewhere	0.000	0.497	0.502
N51.1 Disorders of testis and epididymis in diseases classified elsewhere	0.000	0.497	0.502
N51.0 Disorders of prostate in diseases classified elsewhere	0.000	0.497	0.502
E31.9 Polyglandular dysfunction, unspecified	0.496	0.504	0.000
E31.8 Other polyglandular dysfunction	0.496	0.504	0.000
E31.1 Polyglandular hyperfunction	0.496	0.504	0.000
E20.8 Other hypoparathyroidism	0.487	0.512	0.000
E20.1 Pseudohypoparathyroidism	0.487	0.512	0.000
E20.0 Idiopathic hypoparathyroidism	0.487	0.512	0.000
E24.0 Pituitary-dependent Cushing's disease	0.483	0.517	0.000
E24.8 Other Cushing's syndrome	0.481	0.519	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.481	0.519	0.000
E24.3 Ectopic ACTH syndrome	0.481	0.519	0.000
E24.1 Nelson's syndrome	0.481	0.519	0.000
E06.5 Other chronic thyroiditis	0.476	0.524	0.000
E06.4 Drug-induced thyroiditis	0.476	0.524	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.476	0.524	0.000
E06.1 Subacute thyroiditis	0.476	0.524	0.000
E06.0 Acute thyroiditis	0.476	0.524	0.000
E25.9 Adrenogenital disorder, unspecified	0.470	0.530	0.000
E25.8 Other adrenogenital disorders	0.470	0.530	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.470	0.530	0.000
E30.9 Disorder of puberty, unspecified	0.470	0.530	0.000
E30.8 Other disorders of puberty	0.470	0.530	0.000
E30.1 Precocious puberty	0.470	0.530	0.000
E30.0 Delayed puberty	0.470	0.530	0.000
E32.9 Disease of thymus, unspecified	0.470	0.530	0.000
E32.8 Other diseases of thymus	0.470	0.530	0.000
E32.1 Abscess of thymus	0.470	0.530	0.000
E32.0 Persistent hyperplasia of thymus	0.470	0.530	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.470	0.530	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.470	0.530	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.470	0.530	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.539	0.461
E22 Hyperfunction of pituitary gland	0.456	0.544	0.000
E55 Vitamin D deficiency	0.452	0.548	0.000
K40-K46 Hernia	0.006	0.548	0.445
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.000	0.550	0.450
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.449	0.551	0.000
E53.9 Vitamin B deficiency, unspecified	0.447	0.553	0.000
D64 Other anaemias	0.443	0.557	0.000
E53.1 Pyridoxine deficiency	0.439	0.561	0.000
E53.0 Riboflavin deficiency	0.439	0.561	0.000
E51.2 Wernicke's encephalopathy	0.437	0.563	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.434	0.566	0.000
E45 Retarded development following protein-energy malnutrition	0.434	0.566	0.000
E43 Unspecified severe protein-energy malnutrition	0.434	0.566	0.000
E42 Marasmic kwashiorkor	0.434	0.566	0.000
E41 Nutritional marasmus	0.434	0.566	0.000
E40 Kwashiorkor	0.434	0.566	0.000
E11.2 With renal complications	0.430	0.570	0.000
E24.9 Cushing's syndrome, unspecified	0.429	0.571	0.000
E29.9 Testicular dysfunction, unspecified	0.416	0.584	0.000
E29.8 Other testicular dysfunction	0.416	0.584	0.000
E29.0 Testicular hyperfunction	0.416	0.584	0.000
D80-D89 Certain disorders involving the immune mechanism	0.412	0.588	0.000
E51.9 Thiamine deficiency, unspecified	0.408	0.592	0.000
E51.8 Other manifestations of thiamine deficiency	0.408	0.592	0.000
E51.1 Beriberi	0.408	0.592	0.000
D60-D64 Aplastic and other anaemias	0.407	0.593	0.000
E61.1 Iron deficiency	0.406	0.594	0.000
D86 Sarcoidosis	0.404	0.596	0.000
E14.9 Without complications	0.403	0.597	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.401	0.599	0.000
D86.9 Sarcoidosis, unspecified	0.398	0.602	0.000
E28.3 Primary ovarian failure	0.396	0.604	0.000
K44 Diaphragmatic hernia	0.002	0.605	0.394
E34.8 Other specified endocrine disorders	0.393	0.607	0.000
E28.9 Ovarian dysfunction, unspecified	0.390	0.609	0.000
E28.8 Other ovarian dysfunction	0.390	0.609	0.000
E28.1 Androgen excess	0.390	0.609	0.000
E28.0 Oestrogen excess	0.390	0.609	0.000
N43 Hydrocele and spermatocele	0.000	0.611	0.389
E26.9 Hyperaldosteronism, unspecified	0.388	0.611	0.000
E26.8 Other hyperaldosteronism	0.388	0.611	0.000
E26.1 Secondary hyperaldosteronism	0.388	0.611	0.000
E50.9 Vitamin A deficiency, unspecified	0.388	0.612	0.000
E50.8 Other manifestations of vitamin A deficiency	0.388	0.612	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.388	0.612	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.388	0.612	0.000
E50.5 Vitamin A deficiency with night blindness	0.388	0.612	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.388	0.612	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.388	0.612	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.388	0.612	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.388	0.612	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.388	0.612	0.000
E56.9 Vitamin deficiency, unspecified	0.388	0.612	0.000
E56.8 Deficiency of other vitamins	0.388	0.612	0.000
E56.1 Deficiency of vitamin K	0.388	0.612	0.000
E56.0 Deficiency of vitamin E	0.388	0.612	0.000
E63.9 Nutritional deficiency, unspecified	0.388	0.612	0.000
E63.8 Other specified nutritional deficiencies	0.388	0.612	0.000
E63.1 Imbalance of constituents of food intake	0.388	0.612	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.388	0.612	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.388	0.612	0.000
E64.8 Sequelae of other nutritional deficiencies	0.388	0.612	0.000
E64.3 Sequelae of rickets	0.388	0.612	0.000
E64.2 Sequelae of vitamin C deficiency	0.388	0.612	0.000
E64.1 Sequelae of vitamin A deficiency	0.388	0.612	0.000
E64.0 Sequelae of protein-energy malnutrition	0.388	0.612	0.000
E61.9 Deficiency of nutrient element, unspecified	0.384	0.616	0.000
E61.8 Deficiency of other specified nutrient elements	0.384	0.616	0.000
E61.7 Deficiency of multiple nutrient elements	0.384	0.616	0.000
E61.6 Vanadium deficiency	0.384	0.616	0.000
E61.5 Molybdenum deficiency	0.384	0.616	0.000
E61.4 Chromium deficiency	0.384	0.616	0.000
E61.3 Manganese deficiency	0.384	0.616	0.000
E61.0 Copper deficiency	0.384	0.616	0.000
E34.5 Androgen resistance syndrome	0.380	0.620	0.000
E34.4 Constitutional tall stature	0.380	0.620	0.000
E34.3 Short stature, not elsewhere classified	0.380	0.620	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.380	0.620	0.000
E34.1 Other hypersecretion of intestinal hormones	0.380	0.620	0.000
N48 Other disorders of penis	0.000	0.622	0.378
K41 Femoral hernia	0.002	0.628	0.370
D80 Immunodeficiency with predominantly antibody defects	0.371	0.629	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.364	0.636	0.000
# Top node	0.359	0.641	0.000
E22.1 Hyperprolactinaemia	0.356	0.644	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.356	0.644	0.000
K46 Unspecified abdominal hernia	0.003	0.645	0.352
M20-M25 Other joint disorders	0.353	0.647	0.000
E61.2 Magnesium deficiency	0.353	0.647	0.000
Chapter VII Diseases of the eye and adnexa	0.353	0.647	0.000
M35.0 Sicca syndrome [Sjogren]	0.353	0.647	0.000
M35 Other systemic involvement of connective tissue	0.350	0.650	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.001	0.653	0.346
H30-H36 Disorders of choroid and retina	0.345	0.655	0.000
M60-M63 Disorders of muscles	0.344	0.656	0.000
L30.9 Dermatitis, unspecified	0.342	0.658	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.342	0.658	0.000
K90-K93 Other diseases of the digestive system	0.224	0.659	0.118
E29.1 Testicular hypofunction	0.340	0.659	0.000
H04 Disorders of lachrymal system	0.339	0.661	0.000
H36 Retinal disorders in diseases classified elsewhere	0.338	0.662	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.662	0.338
M62 Other disorders of muscle	0.338	0.662	0.000
M24 Other specific joint derangements	0.337	0.663	0.000
M70-M79 Other soft tissue disorders	0.335	0.665	0.000
L30 Other dermatitis	0.334	0.666	0.000
H36.0 Diabetic retinopathy	0.334	0.666	0.000
M34 Systemic sclerosis	0.334	0.666	0.000
D83 Common variable immunodeficiency	0.333	0.666	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.670	0.330
M75 Shoulder lesions	0.330	0.670	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.001	0.671	0.328
L20-L30 Dermatitis and eczema	0.329	0.671	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.328	0.672	0.000
M62.8 Other specified disorders of muscle	0.328	0.672	0.000
M75.5 Bursitis of shoulder	0.328	0.672	0.000
N48.1 Balanoposthitis	0.000	0.672	0.328
E22.9 Hyperfunction of pituitary gland, unspecified	0.327	0.673	0.000
E22.8 Other hyperfunction of pituitary gland	0.327	0.673	0.000
N48.4 Impotence of organic origin	0.000	0.675	0.325
E55.0 Rickets, active	0.324	0.676	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.322	0.678	0.000
E21.4 Other specified disorders of parathyroid gland	0.322	0.678	0.000
E21.2 Other hyperparathyroidism	0.322	0.678	0.000
E46 Unspecified protein-energy malnutrition	0.321	0.678	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.322	0.678	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.321	0.679	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.320	0.680	0.000
M65-M68 Disorders of synovium and tendon	0.320	0.680	0.000
D64.4 Congenital dyserythropoietic anaemia	0.318	0.682	0.000
D64.3 Other sideroblastic anaemias	0.318	0.682	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.318	0.682	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.318	0.682	0.000
D64.0 Hereditary sideroblastic anaemia	0.318	0.682	0.000
E34.9 Endocrine disorder, unspecified	0.318	0.682	0.000
M31 Other necrotising vasculopathies	0.318	0.682	0.000
M05-M14 Inflammatory polyarthropathies	0.317	0.683	0.000
M72 Fibroblastic disorders	0.317	0.683	0.000
E21.3 Hyperparathyroidism, unspecified	0.317	0.683	0.000
E34.0 Carcinoid syndrome	0.316	0.684	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.316	0.684	0.000
H34 Retinal vascular occlusions	0.315	0.685	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.315	0.685	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.314	0.686	0.000
D84 Other immunodeficiencies	0.313	0.687	0.000
M67 Other disorders of synovium and tendon	0.311	0.689	0.000
E44.1 Mild protein-energy malnutrition	0.311	0.689	0.000
E44.0 Moderate protein-energy malnutrition	0.311	0.689	0.000
N48.2 Other inflammatory disorders of penis	0.000	0.689	0.311
D86.8 Sarcoidosis of other and combined sites	0.311	0.689	0.000
M75.0 Adhesive capsulitis of shoulder	0.310	0.690	0.000
H04.1 Other disorders of lachrymal gland	0.307	0.693	0.000
M67.8 Other specified disorders of synovium and tendon	0.307	0.693	0.000
D86.1 Sarcoidosis of lymph nodes	0.307	0.693	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.303	0.697	0.000
Chapter XI Diseases of the digestive system	0.187	0.697	0.116
Q50-Q56 Congenital malformations of genital organs	0.302	0.698	0.000
M24.1 Other articular cartilage disorders	0.300	0.700	0.000
L28 Lichen simplex chronicus and prurigo	0.300	0.700	0.000
H01 Other inflammation of eyelid	0.299	0.701	0.000
M34.1 CR(E)ST syndrome	0.298	0.702	0.000
M76 Enthesopathies of lower limb, excluding foot	0.296	0.704	0.000
D82 Immunodeficiency associated with other major defects	0.295	0.704	0.000
D81 Combined immunodeficiencies	0.295	0.704	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.294	0.706	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.293	0.707	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.293	0.707	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.292	0.707	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.292	0.708	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.001	0.708	0.291
Chapter XX External causes of morbidity and mortality	0.290	0.710	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.289	0.710	0.000
M31.6 Other giant cell arteritis	0.289	0.711	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.711	0.289
E65-E68 Obesity and other hyperalimentation	0.289	0.711	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.288	0.712	0.000
L10-L14 Bullous disorders	0.288	0.712	0.000
H34.8 Other retinal vascular occlusions	0.287	0.713	0.000
H04.4 Chronic inflammation of lachrymal passages	0.286	0.714	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.284	0.715	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.285	0.715	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.285	0.715	0.000
M75.2 Bicipital tendinitis	0.284	0.716	0.000
H04.6 Other changes in lachrymal passages	0.284	0.716	0.000
K44.1 Diaphragmatic hernia with gangrene	0.001	0.716	0.282
V20-V29 Motorcycle rider injured in transport accident	0.283	0.717	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.283	0.717	0.000
M10 Gout	0.282	0.718	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.281	0.719	0.000
D62 Acute posthaemorrhagic anaemia	0.281	0.719	0.000
D55-D59 Haemolytic anaemias	0.280	0.720	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.280	0.720	0.000
L50-L54 Urticaria and erythema	0.280	0.720	0.000
H01.0 Blepharitis	0.280	0.720	0.000
M32 Systemic lupus erythematosus	0.279	0.721	0.000
N43.2 Other hydrocele	0.000	0.721	0.279
N43.1 Infected hydrocele	0.000	0.721	0.279
N43.0 Encysted hydrocele	0.000	0.721	0.279
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.279	0.721	0.000
D83.9 Common variable immunodeficiency, unspecified	0.277	0.723	0.000
V23.4 Driver injured in traffic accident	0.277	0.723	0.000
M34.9 Systemic sclerosis, unspecified	0.277	0.723	0.000
D89.1 Cryoglobulinaemia	0.276	0.724	0.000
D86.3 Sarcoidosis of skin	0.275	0.725	0.000
E26.0 Primary hyperaldosteronism	0.274	0.725	0.001
M34.8 Other forms of systemic sclerosis	0.275	0.725	0.000
D64.8 Other specified anaemias	0.274	0.726	0.000
E06.3 Autoimmune thyroiditis	0.273	0.726	0.000
H04.8 Other disorders of lachrymal system	0.273	0.727	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.273	0.727	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.273	0.727	0.000
N50 Other disorders of male genital organs	0.000	0.727	0.273
M62.81 Other specified disorders of muscle (Shoulder region)	0.271	0.729	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.270	0.730	0.000
E28.2 Polycystic ovarian syndrome	0.270	0.730	0.000
L40-L45 Papulosquamous disorders	0.268	0.732	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.002	0.733	0.265
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.002	0.733	0.265
K41.1 Bilateral femoral hernia, with gangrene	0.002	0.733	0.265
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.002	0.733	0.265
M76.6 Achilles tendinitis	0.267	0.733	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.267	0.733	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.267	0.733	0.000
M75.8 Other shoulder lesions	0.267	0.733	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.266	0.734	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.266	0.734	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.266	0.734	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.266	0.734	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.266	0.734	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.266	0.734	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.266	0.734	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.266	0.734	0.000
H34.2 Other retinal artery occlusions	0.266	0.734	0.000
M35.7 Hypermobility syndrome	0.265	0.735	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.265	0.735	0.000
N48.5 Ulcer of penis	0.000	0.736	0.264
H30 Chorioretinal inflammation	0.263	0.737	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.262	0.738	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.261	0.739	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.261	0.739	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.261	0.739	0.000
D89.3 Immune reconstitution syndrome	0.261	0.739	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.261	0.739	0.000
M24.7 Protrusio acetabuli	0.260	0.740	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.260	0.740	0.000
D86.0 Sarcoidosis of lung	0.260	0.740	0.000
M24.2 Disorder of ligament	0.259	0.740	0.000
E27.8 Other specified disorders of adrenal gland	0.257	0.741	0.002
M11 Other crystal arthropathies	0.259	0.741	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.258	0.742	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.258	0.742	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.257	0.743	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.257	0.743	0.000
X20-X29 Contact with venomous animals and plants	0.256	0.743	0.000
H43-H45 Disorders of vitreous body and globe	0.256	0.744	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.002	0.745	0.253
W75-W84 Other accidental threats to breathing	0.255	0.745	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.253	0.747	0.000
L43 Lichen planus	0.253	0.747	0.000
M31.0 Hypersensitivity angiitis	0.252	0.748	0.000
M35.2 Behcet's disease	0.251	0.749	0.000
W50-W64 Exposure to animate mechanical forces	0.251	0.749	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.251	0.749	0.000
M35.8 Other specified systemic involvement of connective tissue	0.251	0.749	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.251	0.749	0.000
M35.5 Multifocal fibrosclerosis	0.251	0.749	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.251	0.749	0.000
W20-W49 Exposure to inanimate mechanical forces	0.251	0.749	0.000
M10.0 Idiopathic gout	0.250	0.749	0.000
H31 Other disorders of choroid	0.250	0.750	0.000
K70-K77 Diseases of liver	0.183	0.750	0.067
H10-H13 Disorders of conjunctiva	0.250	0.750	0.000
Q39 Congenital malformations of oesophagus	0.249	0.751	0.000
L28.0 Lichen simplex chronicus	0.249	0.751	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.248	0.752	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.248	0.752	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations