TreeWAS – Variant ID: rs200991

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
E10.3 With ophthalmic complications	0.999	0.001	0.000
E16.2 Hypoglycaemia, unspecified	0.999	0.001	0.000
N40 Hyperplasia of prostate	0.000	0.001	0.999
E20-E35 Disorders of other endocrine glands	0.997	0.003	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.006	0.994
E27 Other disorders of adrenal gland	0.994	0.006	0.000
E27.1 Primary adrenocortical insufficiency	0.991	0.009	0.000
E14 Unspecified diabetes mellitus	0.990	0.010	0.000
K40 Inguinal hernia	0.000	0.018	0.982
K90 Intestinal malabsorption	0.974	0.024	0.002
E14.3 With ophthalmic complications	0.974	0.026	0.000
E10.1 With ketoacidosis	0.968	0.032	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.050	0.950
K40-K46 Hernia	0.006	0.055	0.939
K44 Diaphragmatic hernia	0.002	0.065	0.933
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.070	0.930
E10.2 With renal complications	0.919	0.081	0.000
K90-K93 Other diseases of the digestive system	0.865	0.085	0.050
Chapter XI Diseases of the digestive system	0.859	0.089	0.052
E05.0 Thyrotoxicosis with diffuse goitre	0.904	0.096	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.901	0.099	0.001
M35.0 Sicca syndrome [Sjogren]	0.890	0.110	0.000
H36.0 Diabetic retinopathy	0.885	0.115	0.000
H30-H36 Disorders of choroid and retina	0.885	0.115	0.000
H36 Retinal disorders in diseases classified elsewhere	0.884	0.116	0.000
M35 Other systemic involvement of connective tissue	0.883	0.117	0.000
E23 Hypofunction and other disorders of pituitary gland	0.877	0.123	0.000
M20-M25 Other joint disorders	0.875	0.125	0.000
E14.9 Without complications	0.873	0.127	0.000
# Top node	0.872	0.128	0.000
Chapter VII Diseases of the eye and adnexa	0.872	0.128	0.000
H34 Retinal vascular occlusions	0.865	0.135	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.863	0.137	0.000
E10.5 With peripheral circulatory complications	0.856	0.144	0.000
K75 Other inflammatory liver diseases	0.854	0.146	0.000
K70-K77 Diseases of liver	0.850	0.146	0.004
K75.4 Autoimmune hepatitis	0.852	0.148	0.000
E11 Non-insulin-dependent diabetes mellitus	0.848	0.152	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.847	0.153	0.000
M31 Other necrotising vasculopathies	0.844	0.156	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.843	0.157	0.000
H34.8 Other retinal vascular occlusions	0.838	0.162	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.835	0.165	0.000
M05-M14 Inflammatory polyarthropathies	0.835	0.165	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.832	0.168	0.000
E20 Hypoparathyroidism	0.827	0.173	0.000
M31.6 Other giant cell arteritis	0.826	0.174	0.000
K35-K38 Diseases of appendix	0.791	0.178	0.031
E10.4 With neurological complications	0.822	0.178	0.000
D80-D89 Certain disorders involving the immune mechanism	0.817	0.183	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.808	0.192	0.000
E11.3 With ophthalmic complications	0.807	0.193	0.000
M60-M63 Disorders of muscles	0.806	0.194	0.000
K75.8 Other specified inflammatory liver diseases	0.805	0.195	0.000
E10.0 With coma	0.802	0.198	0.000
K90.9 Intestinal malabsorption, unspecified	0.793	0.206	0.001
E27.4 Other and unspecified adrenocortical insufficiency	0.792	0.207	0.000
L50-L54 Urticaria and erythema	0.792	0.208	0.000
M22 Disorders of patella	0.787	0.213	0.000
E31 Polyglandular dysfunction	0.786	0.214	0.000
D86 Sarcoidosis	0.785	0.215	0.000
K35 Acute appendicitis	0.779	0.220	0.001
L80-L99 Other disorders of the skin and subcutaneous tissue	0.777	0.223	0.000
M62 Other disorders of muscle	0.774	0.226	0.000
E21.0 Primary hyperparathyroidism	0.773	0.227	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.771	0.229	0.000
M20.1 Hallux valgus (acquired)	0.000	0.229	0.771
M34 Systemic sclerosis	0.768	0.232	0.000
L20-L30 Dermatitis and eczema	0.766	0.234	0.000
E25 Adrenogenital disorders	0.765	0.235	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.762	0.238	0.000
K46 Unspecified abdominal hernia	0.003	0.239	0.758
L10-L14 Bullous disorders	0.760	0.240	0.000
K41 Femoral hernia	0.002	0.240	0.758
L97 Ulcer of lower limb, not elsewhere classified	0.760	0.240	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.759	0.241	0.000
E24 Cushing's syndrome	0.755	0.245	0.000
E10.6 With other specified complications	0.752	0.248	0.000
E23.2 Diabetes insipidus	0.752	0.248	0.000
E11.5 With peripheral circulatory complications	0.749	0.251	0.000
E50-E64 Other nutritional deficiencies	0.747	0.253	0.000
D86.9 Sarcoidosis, unspecified	0.747	0.253	0.000
K73 Chronic hepatitis, not elsewhere classified	0.745	0.253	0.002
D50-D53 Nutritional anaemias	0.743	0.257	0.000
E11.6 With other specified complications	0.743	0.257	0.000
E14.2 Withrenal complications	0.742	0.258	0.000
E07 Other disorders of thyroid	0.741	0.259	0.000
K35.9 Acute appendicitis, unspecified	0.739	0.261	0.000
E14.6 With other specified complications	0.736	0.264	0.000
M10 Gout	0.736	0.264	0.000
E27.2 Addisonian crisis	0.736	0.264	0.000
K72 Hepatic failure, not elsewhere classified	0.729	0.270	0.001
H34.2 Other retinal artery occlusions	0.729	0.271	0.000
H25-H28 Disorders of lens	0.728	0.272	0.000
E29 Testicular dysfunction	0.727	0.273	0.000
E27.9 Disorder of adrenal gland, unspecified	0.726	0.274	0.000
E16.1 Other hypoglycaemia	0.726	0.274	0.000
M11 Other crystal arthropathies	0.726	0.274	0.000
L93 Lupus erythematosus	0.723	0.277	0.000
E10.8 With unspecified complications	0.722	0.278	0.000
E14.5 With peripheral circulatory complications	0.719	0.281	0.000
M20 Acquired deformities of fingers and toes	0.007	0.281	0.712
E10.7 With multiple complications	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
L52 Erythema nodosum	0.717	0.283	0.000
L28 Lichen simplex chronicus and prurigo	0.716	0.284	0.000
E14.1 With ketoacidosis	0.716	0.284	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.715	0.285	0.000
E32 Diseases of thymus	0.715	0.285	0.000
E30 Disorders of puberty, not elsewhere classified	0.715	0.285	0.000
E27.5 Adrenomedullary hyperfunction	0.712	0.288	0.000
E27.0 Other adrenocortical overactivity	0.712	0.288	0.000
L53 Other erythematous conditions	0.711	0.289	0.000
E14.7 With multiple complications	0.710	0.290	0.000
E14.0 With coma	0.710	0.290	0.000
E20.9 Hypoparathyroidism, unspecified	0.706	0.294	0.000
M35.3 Polymyalgia rheumatica	0.706	0.294	0.000
E06 Thyroiditis	0.705	0.295	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.704	0.295	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.704	0.296	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.000	0.296	0.704
K40.1 Bilateral inguinal hernia, with gangrene	0.000	0.296	0.704
D50 Iron deficiency anaemia	0.703	0.297	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.701	0.299	0.000
K90.3 Pancreatic steatorrhoea	0.698	0.300	0.002
K90.2 Blind loop syndrome, not elsewhere classified	0.698	0.300	0.002
K90.1 Tropical sprue	0.698	0.300	0.002
M62.8 Other specified disorders of muscle	0.700	0.300	0.000
M32 Systemic lupus erythematosus	0.699	0.300	0.000
M07 Psoriatic and enteropathic arthropathies	0.696	0.304	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.001	0.305	0.694
Q50-Q56 Congenital malformations of genital organs	0.695	0.305	0.000
M22.3 Other derangements of patella	0.694	0.306	0.000
M35.1 Other overlap syndromes	0.692	0.308	0.000
H53-H54 Visual disturbances and blindness	0.691	0.309	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.691	0.309	0.000
E13 Other specified diabetes mellitus	0.690	0.310	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.312	0.688
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.000	0.315	0.684
D60-D64 Aplastic and other anaemias	0.684	0.316	0.000
M14 Arthropathies in other diseases classified elsewhere	0.682	0.318	0.000
E14.4 With neurological complications	0.681	0.319	0.000
K75.9 Inflammatory liver disease, unspecified	0.680	0.320	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.679	0.321	0.000
H43-H45 Disorders of vitreous body and globe	0.678	0.322	0.000
M22.8 Other disorders of patella	0.678	0.322	0.000
M22.2 Patellofemoral disorders	0.678	0.322	0.000
H26 Other cataract	0.677	0.323	0.000
L30 Other dermatitis	0.675	0.325	0.000
E23.0 Hypopituitarism	0.674	0.326	0.000
K44.1 Diaphragmatic hernia with gangrene	0.002	0.330	0.669
L28.0 Lichen simplex chronicus	0.670	0.330	0.000
M62.6 Muscle strain	0.668	0.332	0.000
L94 Other localised connective tissue disorders	0.668	0.332	0.000
L93.0 Discoid lupus erythematosus	0.665	0.335	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.665	0.335	0.000
E23.7 Disorder of pituitary gland, unspecified	0.664	0.336	0.000
H34.1 Central retinal artery occlusion	0.663	0.337	0.000
M10.0 Idiopathic gout	0.662	0.338	0.000
M33 Dermatopolymyositis	0.661	0.338	0.000
H26.9 Cataract, unspecified	0.660	0.340	0.000
L89 Decubitus ulcer	0.660	0.340	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.659	0.340	0.001
D50.9 Iron deficiency anaemia, unspecified	0.659	0.341	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.341	0.658
L13 Other bullous disorders	0.657	0.343	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.620	0.344	0.036
M34.1 CR(E)ST syndrome	0.655	0.345	0.000
K72.0 Acute and subacute hepatic failure	0.651	0.349	0.001
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.651	0.349	0.000
D64 Other anaemias	0.650	0.350	0.000
H35 Other retinal disorders	0.650	0.350	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.650	0.350	0.000
L27 Dermatitis due to substances taken internally	0.649	0.351	0.000
L84 Corns and callosities	0.648	0.352	0.000
D55-D59 Haemolytic anaemias	0.648	0.352	0.000
E14.8 With unspecified complications	0.647	0.352	0.000
H30 Chorioretinal inflammation	0.646	0.354	0.000
M12 Other specific arthropathies	0.646	0.354	0.000
E03.8 Other specified hypothyroidism	0.644	0.355	0.000
L53.8 Other specified erythematous conditions	0.643	0.357	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.640	0.360	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.001	0.360	0.639
H46 Optic neuritis	0.640	0.360	0.000
L81 Other disorders of pigmentation	0.639	0.361	0.000
H54 Blindness and low vision	0.638	0.362	0.000
E53 Deficiency of other B group vitamins	0.637	0.363	0.000
D86.1 Sarcoidosis of lymph nodes	0.636	0.364	0.000
E05.8 Other thyrotoxicosis	0.635	0.364	0.000
E31.0 Autoimmune polyglandular failure	0.635	0.365	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.634	0.365	0.000
K36 Other appendicitis	0.618	0.366	0.016
H36.8 Other retinal disorders in diseases classified elsewhere	0.634	0.366	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.633	0.367	0.000
M35.8 Other specified systemic involvement of connective tissue	0.633	0.367	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.633	0.367	0.000
M35.5 Multifocal fibrosclerosis	0.633	0.367	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.633	0.367	0.000
D64.9 Anaemia, unspecified	0.633	0.367	0.000
E23.6 Other disorders of pituitary gland	0.633	0.367	0.000
M35.7 Hypermobility syndrome	0.632	0.368	0.000
Q00-Q07 Congenital malformations of the nervous system	0.630	0.370	0.000
E11.0 With coma	0.629	0.371	0.000
M31.1 Thrombotic microangiopathy	0.629	0.371	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.629	0.371	0.000
E23.1 Drug-induced hypopituitarism	0.629	0.371	0.000
M13 Other arthritis	0.628	0.372	0.001
D83 Common variable immunodeficiency	0.628	0.372	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.628	0.372	0.000
D50.8 Other iron deficiency anaemias	0.628	0.372	0.000
M00-M03 Infectious arthropathies	0.627	0.373	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.002	0.373	0.625
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.626	0.374	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.625	0.374	0.000
M11.2 Other chondrocalcinosis	0.625	0.375	0.000
L12 Pemphigoid	0.621	0.379	0.000
D80 Immunodeficiency with predominantly antibody defects	0.621	0.379	0.000
K90.8 Other intestinal malabsorption	0.619	0.380	0.002
H34.0 Transient retinal artery occlusion	0.620	0.380	0.000
L30.9 Dermatitis, unspecified	0.620	0.380	0.000
E24.2 Drug-induced Cushing's syndrome	0.618	0.382	0.000
H31 Other disorders of choroid	0.618	0.382	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.615	0.385	0.000
H35.8 Other specified retinal disorders	0.614	0.386	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.613	0.387	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.612	0.387	0.000
K75.2 Nonspecific reactive hepatitis	0.612	0.387	0.000
K75.1 Phlebitis of portal vein	0.612	0.387	0.000
Chapter XX External causes of morbidity and mortality	0.613	0.387	0.000
K77 Liver disorders in diseases classified elsewhere	0.609	0.388	0.003
K71 Toxic liver disease	0.609	0.388	0.003
E11.7 With multiple complications	0.608	0.392	0.000
D84 Other immunodeficiencies	0.608	0.392	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.608	0.392	0.000
E21.4 Other specified disorders of parathyroid gland	0.608	0.392	0.000
E21.2 Other hyperparathyroidism	0.608	0.392	0.000
M31.9 Necrotising vasculopathy, unspecified	0.605	0.395	0.000
M31.8 Other specified necrotising vasculopathies	0.605	0.395	0.000
M31.7 Microscopic polyangiitis	0.605	0.395	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.605	0.395	0.000
M31.2 Lethal midline granuloma	0.605	0.395	0.000
M31.0 Hypersensitivity angiitis	0.605	0.395	0.000
M34.9 Systemic sclerosis, unspecified	0.603	0.397	0.000
Q51 Congenital malformations of uterus and cervix	0.601	0.399	0.000
Q39 Congenital malformations of oesophagus	0.600	0.400	0.000
M35.2 Behcet's disease	0.599	0.401	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.599	0.401	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.599	0.401	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.598	0.402	0.000
M08 Juvenile arthritis	0.598	0.402	0.000
M13.0 Polyarthritis, unspecified	0.597	0.403	0.000
M07.3 Other psoriatic arthropathies	0.597	0.403	0.000
M15-M19 Arthrosis	0.597	0.403	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.596	0.404	0.000
L11 Other acantholytic disorders	0.595	0.404	0.000
E40-E46 Malnutrition	0.595	0.405	0.000
L50 Urticaria	0.594	0.405	0.000
L53.0 Toxic erythema	0.593	0.406	0.000
E20.8 Other hypoparathyroidism	0.593	0.407	0.000
E20.1 Pseudohypoparathyroidism	0.593	0.407	0.000
E20.0 Idiopathic hypoparathyroidism	0.593	0.407	0.000
H27 Other disorders of lens	0.593	0.407	0.000
W00-W19 Falls	0.593	0.407	0.000
E26 Hyperaldosteronism	0.591	0.408	0.000
L93.2 Other local lupus erythematosus	0.586	0.414	0.000
E24.0 Pituitary-dependent Cushing's disease	0.586	0.414	0.000
D82 Immunodeficiency associated with other major defects	0.586	0.414	0.000
D81 Combined immunodeficiencies	0.586	0.414	0.000
D86.3 Sarcoidosis of skin	0.585	0.415	0.000
L13.0 Dermatitis herpetiformis	0.583	0.417	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.582	0.418	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.582	0.418	0.000
H43 Disorders of vitreous body	0.582	0.418	0.000
M06 Other rheumatoid arthritis	0.581	0.419	0.000
L80 Vitiligo	0.581	0.419	0.000
H34.9 Retinal vascular occlusion, unspecified	0.580	0.420	0.000
M65-M68 Disorders of synovium and tendon	0.578	0.422	0.000
E07.8 Other specified disorders of thyroid	0.578	0.422	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.578	0.422	0.000
M61 Calcification and ossification of muscle	0.578	0.422	0.000
D86.0 Sarcoidosis of lung	0.577	0.422	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.577	0.423	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.573	0.426	0.000
M62.0 Diastasis of muscle	0.573	0.427	0.000
M34.8 Other forms of systemic sclerosis	0.572	0.428	0.000
E21.3 Hyperparathyroidism, unspecified	0.571	0.429	0.000
E11.1 With ketoacidosis	0.568	0.432	0.000
L54 Erythema in diseases classified elsewhere	0.568	0.432	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.567	0.433	0.000
M11.9 Crystal arthropathy, unspecified	0.567	0.433	0.000
L92.0 Granuloma annulare	0.567	0.433	0.000
H49 Paralytic strabismus	0.566	0.434	0.000
M22.1 Recurrent subluxation of patella	0.564	0.435	0.000
L81.8 Other specified disorders of pigmentation	0.564	0.436	0.000
E31.9 Polyglandular dysfunction, unspecified	0.564	0.436	0.000
E31.8 Other polyglandular dysfunction	0.564	0.436	0.000
E31.1 Polyglandular hyperfunction	0.564	0.436	0.000
E22 Hyperfunction of pituitary gland	0.563	0.437	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.563	0.437	0.000
K73.9 Chronic hepatitis, unspecified	0.561	0.438	0.001
M20.6 Acquired deformity of toe(s), unspecified	0.002	0.438	0.560
E53.8 Deficiency of other specified B group vitamins	0.562	0.438	0.000
Q45 Other congenital malformations of digestive system	0.562	0.438	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.562	0.438	0.000
D51 Vitamin B12 deficiency anaemia	0.560	0.440	0.000
L28.1 Prurigo nodularis	0.560	0.440	0.000
K50-K52 Noninfective enteritis and colitis	0.477	0.441	0.082
K35.2 Acute appendicitis with generalized peritonitis	0.558	0.441	0.001
H54.7 Unspecified visual loss	0.558	0.442	0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.558	0.442	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.557	0.442	0.000
L87 Transepidermal elimination disorders	0.557	0.442	0.000
L86 Keratoderma in diseases classified elsewhere	0.557	0.442	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.556	0.443	0.000
M30 Polyarteritis nodosa and related conditions	0.556	0.444	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.555	0.445	0.000
M62.9 Disorder of muscle, unspecified	0.555	0.445	0.000
M62.4 Contracture of muscle	0.555	0.445	0.000
M62.3 Immobility syndrome (paraplegic)	0.555	0.445	0.000
M62.2 Ischaemic infarction of muscle	0.555	0.445	0.000
M14.6 Neuropathic arthropathy	0.553	0.446	0.000
Q35-Q37 Cleft lip and cleft palate	0.553	0.447	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.553	0.447	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.553	0.447	0.000
M62.66 Muscle strain (Lower leg)	0.552	0.448	0.000
H43.1 Vitreous haemorrhage	0.552	0.448	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.550	0.449	0.000
M34.0 Progressive systemic sclerosis	0.550	0.449	0.000
K42 Umbilical hernia	0.002	0.450	0.549
L24 Irritant contact dermatitis	0.549	0.451	0.000
L26 Exfoliative dermatitis	0.549	0.451	0.000
L22 Diaper [napkin] dermatitis	0.549	0.451	0.000
E25.9 Adrenogenital disorder, unspecified	0.549	0.451	0.000
E25.8 Other adrenogenital disorders	0.549	0.451	0.000
W19 Unspecified fall	0.549	0.451	0.000
H54.4 Blindness, one eye	0.548	0.451	0.000
X20-X29 Contact with venomous animals and plants	0.548	0.452	0.000
M17 Gonarthrosis [arthrosis of knee]	0.548	0.452	0.000
H26.1 Traumatic cataract	0.548	0.452	0.000
M22.0 Recurrent dislocation of patella	0.547	0.453	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.002	0.454	0.543
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.545	0.454	0.000
E13.3 With ophthalmic complications	0.545	0.455	0.000
L10 Pemphigus	0.545	0.455	0.000
L14 Bullous disorders in diseases classified elsewhere	0.545	0.455	0.000
D86.8 Sarcoidosis of other and combined sites	0.545	0.455	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.002	0.455	0.543
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.002	0.455	0.543
K41.1 Bilateral femoral hernia, with gangrene	0.002	0.455	0.543
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.002	0.455	0.543
L81.9 Disorder of pigmentation, unspecified	0.545	0.455	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.545	0.455	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.544	0.455	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.544	0.456	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.542	0.458	0.000
E34 Other endocrine disorders	0.542	0.458	0.000
E24.8 Other Cushing's syndrome	0.541	0.459	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.541	0.459	0.000
E24.3 Ectopic ACTH syndrome	0.541	0.459	0.000
E24.1 Nelson's syndrome	0.541	0.459	0.000
H33 Retinal detachments and breaks	0.540	0.460	0.000
M10.9 Gout, unspecified	0.539	0.461	0.000
Q39.6 Diverticulum of oesophagus	0.539	0.461	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.538	0.462	0.000
L20 Atopic dermatitis	0.538	0.462	0.000
E51 Thiamine deficiency	0.537	0.463	0.000
Q53 Undescended testicle	0.536	0.463	0.000
Q54 Hypospadias	0.536	0.464	0.000
M10.06 Idiopathic gout (Lower leg)	0.536	0.464	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.536	0.464	0.000
E63 Other nutritional deficiencies	0.536	0.464	0.000
E56 Other vitamin deficiencies	0.536	0.464	0.000
E50 Vitamin A deficiency	0.536	0.464	0.000
E60 Dietary zinc deficiency	0.536	0.464	0.000
E59 Dietary selenium deficiency	0.536	0.464	0.000
E58 Dietary calcium deficiency	0.536	0.464	0.000
E54 Ascorbic acid deficiency	0.536	0.464	0.000
E52 Niacin deficiency [pellagra]	0.536	0.464	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.534	0.464	0.001
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.534	0.464	0.001
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.534	0.464	0.001
D89.1 Cryoglobulinaemia	0.535	0.465	0.000
E29.1 Testicular hypofunction	0.533	0.467	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.532	0.467	0.000
E07.1 Dyshormogenetic goitre	0.531	0.469	0.000
E07.0 Hypersecretion of calcitonin	0.531	0.469	0.000
L23 Allergic contact dermatitis	0.530	0.470	0.000
M22.9 Disorder of patella, unspecified	0.529	0.471	0.000
E06.5 Other chronic thyroiditis	0.528	0.472	0.000
M10.4 Other secondary gout	0.528	0.472	0.000
M10.3 Gout due to impairment of renal function	0.528	0.472	0.000
M10.2 Drug-induced gout	0.528	0.472	0.000
M10.1 Lead-induced gout	0.528	0.472	0.000
H54.6 Unqualified visual loss, one eye	0.528	0.472	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.527	0.473	0.000
L94.2 Calcinosis cutis	0.526	0.474	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.002	0.474	0.523
L51 Erythema multiforme	0.525	0.475	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.524	0.476	0.000
K72.1 Chronic hepatic failure	0.523	0.476	0.001
M62.80 Other specified disorders of muscle (Multiple sites)	0.524	0.476	0.000
Q40 Other congenital malformations of upper alimentary tract	0.524	0.476	0.000
E61 Deficiency of other nutrient elements	0.523	0.477	0.000
V20-V29 Motorcycle rider injured in transport accident	0.523	0.477	0.000
L88 Pyoderma gangrenosum	0.522	0.477	0.000
E29.9 Testicular dysfunction, unspecified	0.521	0.479	0.000
E29.8 Other testicular dysfunction	0.521	0.479	0.000
E29.0 Testicular hyperfunction	0.521	0.479	0.000
M11.8 Other specified crystal arthropathies	0.520	0.479	0.000
M11.1 Familial chondrocalcinosis	0.520	0.479	0.000
M11.0 Hydroxyapatite deposition disease	0.520	0.479	0.000
L94.0 Localised scleroderma [morphea]	0.520	0.480	0.000
M86-M90 Other osteopathies	0.519	0.481	0.000
M17.9 Gonarthrosis, unspecified	0.519	0.481	0.000
L93.1 Subacute cutaneous lupus erythematosus	0.519	0.481	0.000
H49.2 Sixth [abducent] nerve palsy	0.519	0.481	0.000
M14.2 Diabetic arthropathy	0.518	0.482	0.000
M60 Myositis	0.517	0.483	0.000
H52 Disorders of refraction and accommodation	0.517	0.483	0.000
H35.2 Other proliferative retinopathy	0.517	0.483	0.000
L50.0 Allergic urticaria	0.516	0.484	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
E12.9 Without complications	0.514	0.486	0.000
E12.8 With unspecified complications	0.514	0.486	0.000
E12.7 With multiple complications	0.514	0.486	0.000
E12.6 With other specified complications	0.514	0.486	0.000
E12.5 With peripheral circulatory complications	0.514	0.486	0.000
E12.4 With neurological complications	0.514	0.486	0.000
E12.3 With ophthalmic complications	0.514	0.486	0.000
E12.2 With renal complications	0.514	0.486	0.000
E12.1 With ketoacidosis	0.514	0.486	0.000
E12.0 With coma	0.514	0.486	0.000
D59 Acquired haemolytic anaemia	0.514	0.486	0.000
L28.2 Other prurigo	0.514	0.486	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.513	0.487	0.000
E30.9 Disorder of puberty, unspecified	0.513	0.487	0.000
E30.8 Other disorders of puberty	0.513	0.487	0.000
E30.1 Precocious puberty	0.513	0.487	0.000
E30.0 Delayed puberty	0.513	0.487	0.000
E32.9 Disease of thymus, unspecified	0.513	0.487	0.000
E32.8 Other diseases of thymus	0.513	0.487	0.000
E32.1 Abscess of thymus	0.513	0.487	0.000
E32.0 Persistent hyperplasia of thymus	0.513	0.487	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.513	0.487	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.513	0.487	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.513	0.487	0.000
L94.8 Other specified localised connective tissue disorders	0.512	0.488	0.000
M12.2 Villonodular synovitis (pigmented)	0.511	0.489	0.000
Q80-Q89 Other congenital malformations	0.511	0.489	0.000
H47.2 Optic atrophy	0.511	0.489	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.510	0.490	0.000
L53.3 Other chronic figurate erythema	0.510	0.490	0.000
L53.2 Erythema marginatum	0.510	0.490	0.000
L53.1 Erythema annulare centrifugum	0.510	0.490	0.000
Q07 Other congenital malformations of nervous system	0.509	0.491	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.491	0.508
H26.3 Drug-induced cataract	0.507	0.493	0.000
Q52 Other congenital malformations of female genitalia	0.507	0.493	0.000
E06.4 Drug-induced thyroiditis	0.505	0.494	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.505	0.494	0.000
E06.1 Subacute thyroiditis	0.505	0.494	0.000
E06.0 Acute thyroiditis	0.505	0.494	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations