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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs201002
log Bayes Factor = 166.473
Chromosome 6   position 27,808,192  (GRCh37) Explore rs201002 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
N40 Hyperplasia of prostate
0.000 0.000 1.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
D64.9 Anaemia, unspecified
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
D64 Other anaemias
0.999 0.001 0.000
D60-D64 Aplastic and other anaemias
0.999 0.001 0.000
M35.0 Sicca syndrome [Sjogren]
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.973 0.001 0.026
K40 Inguinal hernia
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.000 0.002 0.998
Chapter XII Diseases of the skin and subcutaneous tissue
0.998 0.002 0.000
K90-K93 Other diseases of the digestive system
0.973 0.003 0.025
H30-H36 Disorders of choroid and retina
0.997 0.003 0.000
K90 Intestinal malabsorption
0.995 0.003 0.002
E10.3 With ophthalmic complications
0.997 0.003 0.000
D80-D89 Certain disorders involving the immune mechanism
0.996 0.004 0.000
E20-E35 Disorders of other endocrine glands
0.994 0.006 0.000
H25-H28 Disorders of lens
0.993 0.007 0.000
E27 Other disorders of adrenal gland
0.992 0.008 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.992 0.008 0.000
E27.1 Primary adrenocortical insufficiency
0.990 0.010 0.000
H26 Other cataract
0.990 0.010 0.000
H36 Retinal disorders in diseases classified elsewhere
0.990 0.010 0.000
D86 Sarcoidosis
0.990 0.010 0.000
H26.9 Cataract, unspecified
0.990 0.010 0.000
K40-K46 Hernia
0.002 0.011 0.988
K44 Diaphragmatic hernia
0.001 0.013 0.987
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.013 0.987
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.014 0.986
H36.0 Diabetic retinopathy
0.985 0.015 0.000
M05-M14 Inflammatory polyarthropathies
0.980 0.020 0.000
N40-N51 Diseases of male genital organs
0.000 0.021 0.979
D86.9 Sarcoidosis, unspecified
0.978 0.022 0.000
N42 Other disorders of prostate
0.000 0.024 0.976
K70-K77 Diseases of liver
0.969 0.027 0.005
K75 Other inflammatory liver diseases
0.967 0.032 0.001
E14 Unspecified diabetes mellitus
0.967 0.033 0.000
M23 Internal derangement of knee
0.963 0.037 0.000
K75.4 Autoimmune hepatitis
0.962 0.038 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.962 0.038 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.960 0.040 0.000
L20-L30 Dermatitis and eczema
0.959 0.041 0.000
N42.8 Other specified disorders of prostate
0.000 0.044 0.956
K35-K38 Diseases of appendix
0.944 0.044 0.012
E70-E90 Metabolic disorders
0.955 0.045 0.000
M60-M63 Disorders of muscles
0.955 0.045 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.954 0.046 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.950 0.050 0.000
L50-L54 Urticaria and erythema
0.948 0.052 0.000
N32.0 Bladder-neck obstruction
0.000 0.054 0.946
M31 Other necrotising vasculopathies
0.943 0.057 0.000
M22 Disorders of patella
0.942 0.058 0.000
N39 Other disorders of urinary system
0.000 0.059 0.941
N30-N39 Other diseases of urinary system
0.000 0.060 0.940
N32 Other disorders of bladder
0.000 0.062 0.938
K35 Acute appendicitis
0.935 0.064 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.934 0.066 0.000
M70-M79 Other soft tissue disorders
0.932 0.068 0.000
H34 Retinal vascular occlusions
0.932 0.068 0.000
N39.8 Other specified disorders of urinary system
0.000 0.069 0.931
M34 Systemic sclerosis
0.931 0.069 0.000
E78.5 Hyperlipidaemia, unspecified
0.930 0.070 0.000
M11 Other crystal arthropathies
0.927 0.073 0.000
K51 Ulcerative colitis
0.000 0.073 0.926
M62 Other disorders of muscle
0.926 0.074 0.000
M72 Fibroblastic disorders
0.925 0.075 0.000
E10.1 With ketoacidosis
0.925 0.075 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.076 0.924
K51.9 Ulcerative colitis, unspecified
0.000 0.078 0.922
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.922 0.078 0.000
E14.3 With ophthalmic complications
0.922 0.078 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.921 0.079 0.000
K35.9 Acute appendicitis, unspecified
0.921 0.079 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.081 0.919
M20.1 Hallux valgus (acquired)
0.000 0.082 0.918
M20 Acquired deformities of fingers and toes
0.001 0.084 0.915
E10.2 With renal complications
0.915 0.085 0.000
H43-H45 Disorders of vitreous body and globe
0.912 0.088 0.000
K72 Hepatic failure, not elsewhere classified
0.910 0.089 0.002
M20.5 Other deformities of toe(s) (acquired)
0.000 0.090 0.910
H47 Other disorders of optic [2nd] nerve and visual pathways
0.910 0.090 0.000
L30 Other dermatitis
0.909 0.091 0.000
M10 Gout
0.906 0.094 0.000
M15-M19 Arthrosis
0.906 0.094 0.000
L40-L45 Papulosquamous disorders
0.905 0.095 0.000
N39.0 Urinary tract infection, site not specified
0.000 0.098 0.902
L10-L14 Bullous disorders
0.902 0.098 0.000
M17 Gonarthrosis [arthrosis of knee]
0.897 0.103 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.891 0.109 0.000
K75.8 Other specified inflammatory liver diseases
0.889 0.111 0.000
M31.6 Other giant cell arteritis
0.887 0.113 0.000
K90.9 Intestinal malabsorption, unspecified
0.885 0.114 0.000
L94 Other localised connective tissue disorders
0.882 0.118 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.882 0.118 0.000
H02 Other disorders of eyelid
0.882 0.118 0.000
I73 Other peripheral vascular diseases
0.880 0.120 0.000
M62.8 Other specified disorders of muscle
0.880 0.120 0.000
L93 Lupus erythematosus
0.877 0.123 0.000
L30.9 Dermatitis, unspecified
0.877 0.123 0.000
L43 Lichen planus
0.876 0.124 0.000
H34.8 Other retinal vascular occlusions
0.874 0.126 0.000
L52 Erythema nodosum
0.873 0.127 0.000
M11.2 Other chondrocalcinosis
0.873 0.127 0.000
I73.9 Peripheral vascular disease, unspecified
0.872 0.128 0.000
E10.4 With neurological complications
0.871 0.129 0.000
M20.4 Other hammer toe(s) (acquired)
0.000 0.130 0.870
M17.9 Gonarthrosis, unspecified
0.870 0.130 0.000
M22.3 Other derangements of patella
0.869 0.131 0.000
K73 Chronic hepatitis, not elsewhere classified
0.864 0.134 0.002
E16.0 Drug-induced hypoglycaemia without coma
0.864 0.136 0.000
M35.3 Polymyalgia rheumatica
0.863 0.137 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.862 0.138 0.000
H43 Disorders of vitreous body
0.861 0.139 0.000
N39.9 Disorder of urinary system, unspecified
0.000 0.142 0.858
E78.6 Lipoprotein deficiency
0.857 0.143 0.000
L43.9 Lichen planus, unspecified
0.857 0.143 0.000
I77 Other disorders of arteries and arterioles
0.856 0.144 0.000
H02.5 Other disorders affecting eyelid function
0.854 0.146 0.000
K51.4 Pseudopolyposis of colon
0.000 0.150 0.850
M23.3 Other meniscus derangements
0.850 0.150 0.000
K72.0 Acute and subacute hepatic failure
0.849 0.150 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.849 0.151 0.000
H43.1 Vitreous haemorrhage
0.849 0.151 0.000
H02.1 Ectropion of eyelid
0.846 0.154 0.000
M17.1 Other primary gonarthrosis
0.843 0.157 0.000
L28 Lichen simplex chronicus and prurigo
0.840 0.160 0.000
N36 Other disorders of urethra
0.000 0.160 0.840
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.837 0.163 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.834 0.166 0.000
H01 Other inflammation of eyelid
0.832 0.168 0.000
H27 Other disorders of lens
0.830 0.170 0.000
N39.3 Stress incontinence
0.000 0.172 0.828
L27 Dermatitis due to substances taken internally
0.826 0.174 0.000
M22.8 Other disorders of patella
0.824 0.176 0.000
E10.5 With peripheral circulatory complications
0.821 0.179 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.820 0.179 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.819 0.181 0.000
K46 Unspecified abdominal hernia
0.001 0.182 0.817
E20 Hypoparathyroidism
0.817 0.183 0.000
M10.0 Idiopathic gout
0.816 0.184 0.000
I74 Arterial embolism and thrombosis
0.815 0.185 0.000
E83 Disorders of mineral metabolism
0.745 0.187 0.068
E23 Hypofunction and other disorders of pituitary gland
0.811 0.189 0.000
E14.9 Without complications
0.810 0.190 0.000
M23.9 Internal derangement of knee, unspecified
0.808 0.192 0.000
M34.1 CR(E)ST syndrome
0.807 0.193 0.000
H46 Optic neuritis
0.805 0.195 0.000
Chapter IX Diseases of the circulatory system
0.805 0.195 0.000
Chapter XIV Diseases of the genitourinary system
0.002 0.196 0.803
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.802 0.197 0.001
H26.1 Traumatic cataract
0.803 0.197 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.197 0.803
L89 Decubitus ulcer
0.803 0.197 0.000
D83 Common variable immunodeficiency
0.802 0.197 0.000
Q50-Q56 Congenital malformations of genital organs
0.802 0.198 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.802 0.198 0.000
M23.4 Loose body in knee
0.801 0.199 0.000
K75.9 Inflammatory liver disease, unspecified
0.801 0.199 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.801 0.199 0.000
D80 Immunodeficiency with predominantly antibody defects
0.800 0.200 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.799 0.201 0.000
H47.2 Optic atrophy
0.798 0.202 0.000
I77.1 Stricture of artery
0.798 0.202 0.000
H26.4 After-cataract
0.797 0.203 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.206 0.794
M23.2 Derangement of meniscus due to old tear or injury
0.793 0.207 0.000
N34 Urethritis and urethral syndrome
0.000 0.208 0.792
D86.8 Sarcoidosis of other and combined sites
0.791 0.209 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.791 0.209 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.788 0.212 0.000
H31 Other disorders of choroid
0.786 0.213 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.786 0.214 0.000
E78.1 Pure hyperglyceridaemia
0.786 0.214 0.000
I77.6 Arteritis, unspecified
0.785 0.215 0.000
N46 Male infertility
0.000 0.216 0.784
H03 Disorders of eyelid in diseases classified elsewhere
0.783 0.217 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.783 0.217 0.000
K36 Other appendicitis
0.776 0.218 0.006
L50 Urticaria
0.781 0.219 0.000
N36.2 Urethral caruncle
0.000 0.220 0.780
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.780 0.220 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.221 0.779
M35.7 Hypermobility syndrome
0.779 0.221 0.000
I70 Atherosclerosis
0.779 0.221 0.000
E07 Other disorders of thyroid
0.778 0.222 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.778 0.222 0.000
E31 Polyglandular dysfunction
0.777 0.223 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.776 0.223 0.001
H47.3 Other disorders of optic disk
0.777 0.223 0.000
L93.0 Discoid lupus erythematosus
0.776 0.224 0.000
D86.1 Sarcoidosis of lymph nodes
0.775 0.225 0.000
E78.4 Other hyperlipidaemia
0.772 0.228 0.000
K50-K52 Noninfective enteritis and colitis
0.156 0.228 0.616
H30 Chorioretinal inflammation
0.771 0.229 0.000
L81 Other disorders of pigmentation
0.771 0.229 0.000
M35.1 Other overlap syndromes
0.770 0.230 0.000
L80 Vitiligo
0.769 0.231 0.000
H01.0 Blepharitis
0.768 0.232 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.768 0.232 0.000
M23.0 Cystic meniscus
0.766 0.234 0.000
D55-D59 Haemolytic anaemias
0.765 0.235 0.000
N41 Inflammatory diseases of prostate
0.000 0.235 0.765
K35.0 Acute appendicitis with generalised peritonitis
0.765 0.235 0.000
M34.9 Systemic sclerosis, unspecified
0.765 0.235 0.000
E50-E64 Other nutritional deficiencies
0.763 0.237 0.000
M24 Other specific joint derangements
0.763 0.237 0.000
M34.8 Other forms of systemic sclerosis
0.763 0.237 0.000
N45 Orchitis and epididymitis
0.000 0.238 0.762
N42.0 Calculus of prostate
0.000 0.238 0.762
L92.0 Granuloma annulare
0.761 0.239 0.000
M06 Other rheumatoid arthritis
0.761 0.239 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.760 0.240 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.760 0.240 0.000
D86.3 Sarcoidosis of skin
0.759 0.241 0.000
M10.9 Gout, unspecified
0.758 0.242 0.000
M32 Systemic lupus erythematosus
0.757 0.243 0.000
H02.0 Entropion and trichiasis of eyelid
0.757 0.243 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.245 0.755
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.755 0.245 0.000
L13 Other bullous disorders
0.755 0.245 0.000
H34.2 Other retinal artery occlusions
0.755 0.245 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.246 0.753
H53-H54 Visual disturbances and blindness
0.752 0.248 0.000
L53 Other erythematous conditions
0.751 0.249 0.000
E84 Cystic fibrosis
0.750 0.250 0.000
M76 Enthesopathies of lower limb, excluding foot
0.750 0.250 0.000
M11.9 Crystal arthropathy, unspecified
0.748 0.252 0.000
E78.8 Other disorders of lipoprotein metabolism
0.747 0.253 0.000
L94.0 Localised scleroderma [morphea]
0.746 0.254 0.000
E11 Non-insulin-dependent diabetes mellitus
0.746 0.254 0.000
D50-D53 Nutritional anaemias
0.746 0.254 0.000
M62.6 Muscle strain
0.743 0.257 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.257 0.743
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.258 0.742
E10.0 With coma
0.742 0.258 0.000
E10.6 With other specified complications
0.739 0.261 0.000
E74 Other disorders of carbohydrate metabolism
0.738 0.262 0.000
D84 Other immunodeficiencies
0.736 0.264 0.000
I73.0 Raynaud's syndrome
0.734 0.266 0.000
E73 Lactose intolerance
0.734 0.266 0.000
M31.1 Thrombotic microangiopathy
0.733 0.267 0.000
K72.9 Hepatic failure, unspecified
0.731 0.268 0.001
M62.81 Other specified disorders of muscle (Shoulder region)
0.731 0.269 0.000
E06 Thyroiditis
0.730 0.270 0.000
E24 Cushing's syndrome
0.729 0.270 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.729 0.271 0.000
M07 Psoriatic and enteropathic arthropathies
0.729 0.271 0.000
L93.2 Other local lupus erythematosus
0.729 0.271 0.000
L11 Other acantholytic disorders
0.728 0.272 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.728 0.272 0.000
E14.2 Withrenal complications
0.728 0.272 0.000
E10.8 With unspecified complications
0.728 0.272 0.000
E13 Other specified diabetes mellitus
0.727 0.273 0.000
M33 Dermatopolymyositis
0.727 0.273 0.000
D86.0 Sarcoidosis of lung
0.726 0.274 0.000
K41 Femoral hernia
0.001 0.274 0.725
N32.1 Vesicointestinal fistula
0.000 0.274 0.726
L12 Pemphigoid
0.725 0.275 0.000
M22.2 Patellofemoral disorders
0.724 0.276 0.000
L28.0 Lichen simplex chronicus
0.724 0.276 0.000
K35.2 Acute appendicitis with generalized peritonitis
0.723 0.277 0.000
L94.2 Calcinosis cutis
0.722 0.278 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.721 0.279 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.721 0.279 0.000
E27.9 Disorder of adrenal gland, unspecified
0.720 0.280 0.000
M12 Other specific arthropathies
0.719 0.281 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.719 0.281 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.8 Other specified systemic involvement of connective tissue
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.716 0.283 0.000
D64.3 Other sideroblastic anaemias
0.716 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.716 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.716 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.716 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.716 0.283 0.000
E27.2 Addisonian crisis
0.716 0.283 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.284 0.716
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.284 0.716
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.697 0.285 0.018
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.715 0.285 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.715 0.285 0.000
K90.3 Pancreatic steatorrhoea
0.713 0.285 0.001
K90.2 Blind loop syndrome, not elsewhere classified
0.713 0.285 0.001
K90.1 Tropical sprue
0.713 0.285 0.001
D82 Immunodeficiency associated with other major defects
0.714 0.285 0.000
D81 Combined immunodeficiencies
0.714 0.285 0.000
E14.1 With ketoacidosis
0.714 0.286 0.000
M13 Other arthritis
0.713 0.287 0.001
E35 Disorders of endocrine glands in diseases classified elsewhere
0.713 0.287 0.000
E32 Diseases of thymus
0.713 0.287 0.000
E30 Disorders of puberty, not elsewhere classified
0.713 0.287 0.000
E25 Adrenogenital disorders
0.713 0.287 0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.287 0.713
E16.1 Other hypoglycaemia
0.713 0.287 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.712 0.288 0.000
I77.8 Other specified disorders of arteries and arterioles
0.712 0.288 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.712 0.288 0.000
E27.5 Adrenomedullary hyperfunction
0.711 0.288 0.000
E27.0 Other adrenocortical overactivity
0.711 0.288 0.000
M00-M03 Infectious arthropathies
0.711 0.289 0.000
H26.3 Drug-induced cataract
0.710 0.290 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.710 0.290 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.710 0.290 0.000
L23 Allergic contact dermatitis
0.708 0.292 0.000
K44.1 Diaphragmatic hernia with gangrene
0.001 0.292 0.707
H35 Other retinal disorders
0.707 0.293 0.000
H47.1 Papilloedema, unspecified
0.706 0.294 0.000
M65-M68 Disorders of synovium and tendon
0.706 0.294 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.706 0.294 0.000
M62.0 Diastasis of muscle
0.706 0.294 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.705 0.295 0.000
E83.5 Disorders of calcium metabolism
0.701 0.296 0.004
M35.2 Behcet's disease
0.703 0.297 0.000
H05 Disorders of orbit
0.703 0.297 0.000
H02.6 Xanthelasma of eyelid
0.703 0.297 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.702 0.298 0.000
M08 Juvenile arthritis
0.702 0.298 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.298 0.702
N44 Torsion of testis
0.000 0.298 0.702
M62.82 Other specified disorders of muscle (Upper arm)
0.700 0.300 0.000
N42.3 Dysplasia of prostate
0.000 0.300 0.700
L27.0 Generalised skin eruption due to drugs and medicaments
0.700 0.300 0.000
K77 Liver disorders in diseases classified elsewhere
0.695 0.302 0.004
K71 Toxic liver disease
0.695 0.302 0.004
M23.1 Discoid meniscus (congenital)
0.697 0.303 0.000
M30 Polyarteritis nodosa and related conditions
0.695 0.305 0.000
D61 Other aplastic anaemias
0.694 0.306 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.694 0.306 0.001
K75.2 Nonspecific reactive hepatitis
0.694 0.306 0.001
K75.1 Phlebitis of portal vein
0.694 0.306 0.001
E14.8 With unspecified complications
0.694 0.306 0.000
E14.7 With multiple complications
0.694 0.306 0.000
E14.6 With other specified complications
0.694 0.306 0.000
E14.5 With peripheral circulatory complications
0.694 0.306 0.000
E14.0 With coma
0.694 0.306 0.000
M23.49 Loose body in knee-Unspec lig/men
0.691 0.309 0.000
E20.9 Hypoparathyroidism, unspecified
0.690 0.310 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.689 0.310 0.000
L87 Transepidermal elimination disorders
0.689 0.310 0.000
L88 Pyoderma gangrenosum
0.689 0.310 0.000
L86 Keratoderma in diseases classified elsewhere
0.689 0.310 0.000
M17.0 Primary gonarthrosis, bilateral
0.689 0.311 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.688 0.312 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.312 0.688
L89.9 Decubitus ulcer and pressure area, unspecified
0.688 0.312 0.000
L25 Unspecified contact dermatitis
0.687 0.313 0.000
L24 Irritant contact dermatitis
0.687 0.313 0.000
L26 Exfoliative dermatitis
0.687 0.313 0.000
L22 Diaper [napkin] dermatitis
0.687 0.313 0.000
M15 Polyarthrosis
0.687 0.313 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.686 0.314 0.000
L81.9 Disorder of pigmentation, unspecified
0.686 0.314 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.685 0.315 0.000
E79 Disorders of purine and pyrimidine metabolism
0.685 0.315 0.000
E77 Disorders of glycoprotein metabolism
0.685 0.315 0.000
E76 Disorders of glycosaminoglycan metabolism
0.685 0.315 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.685 0.315 0.000
E72 Other disorders of amino-acid metabolism
0.685 0.315 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.685 0.315 0.000
E70 Disorders of aromatic amino-acid metabolism
0.685 0.315 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.685 0.315 0.000
L94.9 Localised connective tissue disorder, unspecified
0.685 0.315 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.684 0.316 0.000
M61 Calcification and ossification of muscle
0.684 0.316 0.000
L84 Corns and callosities
0.684 0.316 0.000
H54 Blindness and low vision
0.683 0.317 0.000
K90.8 Other intestinal malabsorption
0.682 0.317 0.001
E11.3 With ophthalmic complications
0.683 0.317 0.000
I78 Diseases of capillaries
0.682 0.318 0.000
Q51 Congenital malformations of uterus and cervix
0.682 0.318 0.000
E78.3 Hyperchylomicronaemia
0.681 0.319 0.000
M22.0 Recurrent dislocation of patella
0.681 0.319 0.000
H27.0 Aphakia
0.681 0.319 0.000
L54 Erythema in diseases classified elsewhere
0.680 0.320 0.000
L50.0 Allergic urticaria
0.678 0.321 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.678 0.322 0.000
L94.8 Other specified localised connective tissue disorders
0.678 0.322 0.000
M75 Shoulder lesions
0.678 0.322 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.677 0.323 0.000
E78.2 Mixed hyperlipidaemia
0.676 0.324 0.000
M31.9 Necrotising vasculopathy, unspecified
0.676 0.324 0.000
M31.8 Other specified necrotising vasculopathies
0.676 0.324 0.000
M31.7 Microscopic polyangiitis
0.676 0.324 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.676 0.324 0.000
M31.2 Lethal midline granuloma
0.676 0.324 0.000
M31.0 Hypersensitivity angiitis
0.676 0.324 0.000
M22.1 Recurrent subluxation of patella
0.676 0.324 0.000
M22.9 Disorder of patella, unspecified
0.676 0.324 0.000
N39.2 Orthostatic proteinuria, unspecified
0.000 0.325 0.675
N34.2 Other urethritis
0.000 0.326 0.674
N37 Urethral disorders in diseases classified elsewhere
0.000 0.326 0.674
N33 Bladder disorders in diseases classified elsewhere
0.000 0.326 0.674
K51.8 Other ulcerative colitis
0.000 0.327 0.673
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.673 0.327 0.000
N32.4 Rupture of bladder, nontraumatic
0.000 0.327 0.673
N32.2 Vesical fistula, not elsewhere classified
0.000 0.327 0.673
L20 Atopic dermatitis
0.672 0.328 0.000
L51 Erythema multiforme
0.672 0.328 0.000
I70.0 Atherosclerosis of aorta
0.671 0.329 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.671 0.329 0.000
E05.8 Other thyrotoxicosis
0.670 0.330 0.000
M06.9 Rheumatoid arthritis, unspecified
0.670 0.330 0.000
H04 Disorders of lachrymal system
0.669 0.331 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.668 0.332 0.000
H34.0 Transient retinal artery occlusion
0.668 0.332 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.667 0.333 0.000
M34.0 Progressive systemic sclerosis
0.667 0.333 0.000
L28.1 Prurigo nodularis
0.667 0.333 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.666 0.334 0.000
M11.8 Other specified crystal arthropathies
0.665 0.335 0.000
M11.1 Familial chondrocalcinosis
0.665 0.335 0.000
M11.0 Hydroxyapatite deposition disease
0.665 0.335 0.000
M62.9 Disorder of muscle, unspecified
0.664 0.336 0.000
M62.4 Contracture of muscle
0.664 0.336 0.000
M62.3 Immobility syndrome (paraplegic)
0.664 0.336 0.000
M62.2 Ischaemic infarction of muscle
0.664 0.336 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.664 0.336 0.000
E14.4 With neurological complications
0.664 0.336 0.000
Q39 Congenital malformations of oesophagus
0.664 0.336 0.000
D83.9 Common variable immunodeficiency, unspecified
0.663 0.336 0.000
M72.9 Fibroblastic disorder, unspecified
0.663 0.336 0.000
M72.8 Other fibroblastic disorders
0.663 0.336 0.000
M72.6 Necrotizing fasciitis
0.663 0.336 0.000
M72.5 Fasciitis, not elsewhere classified
0.663 0.336 0.000
M72.4 Pseudosarcomatous fibromatosis
0.663 0.336 0.000
M72.3 Nodular fasciitis
0.663 0.336 0.000
M72.1 Knuckle pads
0.663 0.336 0.000
E29 Testicular dysfunction
0.663 0.337 0.000
E03.8 Other specified hypothyroidism
0.662 0.338 0.000
Q53 Undescended testicle
0.662 0.338 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.662 0.338 0.000
N36.3 Prolapsed urethral mucosa
0.000 0.338 0.661
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec
0.661 0.339 0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other
0.661 0.339 0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot
0.661 0.339 0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg
0.661 0.339 0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh
0.661 0.339 0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm
0.661 0.339 0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm
0.661 0.339 0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region
0.661 0.339 0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites
0.661 0.339 0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere
0.661 0.339 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.661 0.339 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.661 0.339 0.000
M13.0 Polyarthritis, unspecified
0.660 0.339 0.000
H06.2 Dysthyroid exophthalmos
0.660 0.340 0.000
M14 Arthropathies in other diseases classified elsewhere
0.659 0.341 0.000
M10.06 Idiopathic gout (Lower leg)
0.658 0.342 0.000
Q00-Q07 Congenital malformations of the nervous system
0.656 0.344 0.000
K73.9 Chronic hepatitis, unspecified
0.654 0.345 0.001
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.654 0.346 0.000
E23.2 Diabetes insipidus
0.653 0.346 0.000
K72.1 Chronic hepatic failure
0.652 0.346 0.001
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.347 0.653
H47.7 Disorder of visual pathways, unspecified
0.652 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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