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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs201004
log Bayes Factor = 104.553
Chromosome 6   position 27,804,934  (GRCh37) Explore rs201004 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
N40 Hyperplasia of prostate
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
0.999 0.001 0.000
E16.2 Hypoglycaemia, unspecified
0.999 0.001 0.000
E14 Unspecified diabetes mellitus
0.999 0.001 0.000
E20-E35 Disorders of other endocrine glands
0.996 0.004 0.000
E10.3 With ophthalmic complications
0.995 0.005 0.000
R31 Unspecified haematuria
0.000 0.007 0.993
E27 Other disorders of adrenal gland
0.989 0.011 0.000
E14.3 With ophthalmic complications
0.986 0.014 0.000
E27.1 Primary adrenocortical insufficiency
0.984 0.016 0.000
E14.9 Without complications
0.959 0.041 0.000
E10.1 With ketoacidosis
0.952 0.048 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.064 0.936
E10.2 With renal complications
0.927 0.073 0.000
K90 Intestinal malabsorption
0.900 0.100 0.000
E23 Hypofunction and other disorders of pituitary gland
0.899 0.101 0.000
K40 Inguinal hernia
0.000 0.102 0.898
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.883 0.117 0.000
E10.7 With multiple complications
0.849 0.151 0.000
E10.4 With neurological complications
0.848 0.152 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.844 0.156 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.841 0.159 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.170 0.830
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.178 0.822
E14.6 With other specified complications
0.818 0.182 0.000
K44 Diaphragmatic hernia
0.000 0.183 0.817
K40-K46 Hernia
0.000 0.184 0.816
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.804 0.196 0.000
E10.5 With peripheral circulatory complications
0.798 0.202 0.000
K90.9 Intestinal malabsorption, unspecified
0.797 0.203 0.000
E31 Polyglandular dysfunction
0.795 0.205 0.000
E21.0 Primary hyperparathyroidism
0.792 0.208 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.790 0.210 0.000
E24 Cushing's syndrome
0.789 0.211 0.000
E23.2 Diabetes insipidus
0.786 0.214 0.000
E20 Hypoparathyroidism
0.779 0.220 0.000
E10.0 With coma
0.775 0.225 0.000
E50-E64 Other nutritional deficiencies
0.769 0.231 0.000
E11 Non-insulin-dependent diabetes mellitus
0.766 0.234 0.000
E14.5 With peripheral circulatory complications
0.752 0.247 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.752 0.248 0.000
E14.2 Withrenal complications
0.752 0.248 0.000
E11.3 With ophthalmic complications
0.747 0.253 0.000
E25 Adrenogenital disorders
0.747 0.253 0.000
E07 Other disorders of thyroid
0.746 0.254 0.000
E27.2 Addisonian crisis
0.744 0.256 0.000
E10.8 With unspecified complications
0.743 0.257 0.000
E10.6 With other specified complications
0.726 0.274 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.723 0.277 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E14.1 With ketoacidosis
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.283 0.000
E16.3 Increased secretion of glucagon
0.716 0.283 0.000
E14.7 With multiple complications
0.716 0.284 0.000
E14.0 With coma
0.716 0.284 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.714 0.285 0.000
E32 Diseases of thymus
0.714 0.285 0.000
E30 Disorders of puberty, not elsewhere classified
0.714 0.285 0.000
E27.5 Adrenomedullary hyperfunction
0.709 0.291 0.000
E27.0 Other adrenocortical overactivity
0.709 0.291 0.000
E13 Other specified diabetes mellitus
0.708 0.292 0.000
E14.8 With unspecified complications
0.705 0.294 0.000
E23.0 Hypopituitarism
0.701 0.299 0.000
E14.4 With neurological complications
0.701 0.299 0.000
E16.1 Other hypoglycaemia
0.699 0.301 0.000
E11.5 With peripheral circulatory complications
0.699 0.301 0.000
E03.8 Other specified hypothyroidism
0.697 0.303 0.000
E23.7 Disorder of pituitary gland, unspecified
0.677 0.323 0.000
E53 Deficiency of other B group vitamins
0.676 0.324 0.000
E27.9 Disorder of adrenal gland, unspecified
0.676 0.324 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.328 0.672
E23.6 Other disorders of pituitary gland
0.668 0.332 0.000
E21.3 Hyperparathyroidism, unspecified
0.661 0.339 0.000
E40-E46 Malnutrition
0.656 0.344 0.000
E11.6 With other specified complications
0.656 0.344 0.000
E24.2 Drug-induced Cushing's syndrome
0.652 0.348 0.000
E31.0 Autoimmune polyglandular failure
0.651 0.349 0.000
K90.3 Pancreatic steatorrhoea
0.645 0.355 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.645 0.355 0.000
K90.1 Tropical sprue
0.645 0.355 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.645 0.355 0.000
E23.1 Drug-induced hypopituitarism
0.645 0.355 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.356 0.644
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.356 0.644
E29 Testicular dysfunction
0.634 0.366 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.633 0.367 0.000
E21.4 Other specified disorders of parathyroid gland
0.633 0.367 0.000
E21.2 Other hyperparathyroidism
0.633 0.367 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.629 0.370 0.000
K90.8 Other intestinal malabsorption
0.628 0.372 0.000
E20.9 Hypoparathyroidism, unspecified
0.624 0.376 0.000
E53.8 Deficiency of other specified B group vitamins
0.623 0.377 0.000
E05.8 Other thyrotoxicosis
0.616 0.384 0.000
E24.0 Pituitary-dependent Cushing's disease
0.609 0.391 0.000
E22 Hyperfunction of pituitary gland
0.595 0.405 0.000
E07.8 Other specified disorders of thyroid
0.592 0.407 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.590 0.410 0.000
K42 Umbilical hernia
0.000 0.411 0.589
E06 Thyroiditis
0.589 0.411 0.000
K44.1 Diaphragmatic hernia with gangrene
0.000 0.414 0.586
E34 Other endocrine disorders
0.585 0.415 0.000
E26 Hyperaldosteronism
0.576 0.424 0.000
E31.9 Polyglandular dysfunction, unspecified
0.570 0.430 0.000
E31.8 Other polyglandular dysfunction
0.570 0.430 0.000
E31.1 Polyglandular hyperfunction
0.570 0.430 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.567 0.432 0.000
E24.8 Other Cushing's syndrome
0.566 0.434 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.566 0.434 0.000
E24.3 Ectopic ACTH syndrome
0.566 0.434 0.000
E24.1 Nelson's syndrome
0.566 0.434 0.000
E13.3 With ophthalmic complications
0.565 0.435 0.000
E20.8 Other hypoparathyroidism
0.559 0.441 0.000
E20.1 Pseudohypoparathyroidism
0.559 0.441 0.000
E20.0 Idiopathic hypoparathyroidism
0.559 0.441 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.446 0.553
K46 Unspecified abdominal hernia
0.000 0.448 0.552
E64 Sequelae of malnutrition and other nutritional deficiencies
0.551 0.448 0.000
E63 Other nutritional deficiencies
0.551 0.448 0.000
E56 Other vitamin deficiencies
0.551 0.448 0.000
E50 Vitamin A deficiency
0.551 0.448 0.000
E60 Dietary zinc deficiency
0.551 0.448 0.000
E59 Dietary selenium deficiency
0.551 0.448 0.000
E58 Dietary calcium deficiency
0.551 0.448 0.000
E54 Ascorbic acid deficiency
0.551 0.448 0.000
E52 Niacin deficiency [pellagra]
0.551 0.448 0.000
E11.7 With multiple complications
0.549 0.450 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.453 0.547
E11.0 With coma
0.538 0.462 0.000
E51 Thiamine deficiency
0.538 0.462 0.000
E25.9 Adrenogenital disorder, unspecified
0.535 0.464 0.000
E25.8 Other adrenogenital disorders
0.535 0.464 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.000 0.465 0.535
E07.1 Dyshormogenetic goitre
0.535 0.465 0.000
E07.0 Hypersecretion of calcitonin
0.535 0.465 0.000
K41 Femoral hernia
0.000 0.467 0.533
E22.1 Hyperprolactinaemia
0.527 0.473 0.000
E61 Deficiency of other nutrient elements
0.524 0.476 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E30.9 Disorder of puberty, unspecified
0.512 0.488 0.000
E30.8 Other disorders of puberty
0.512 0.488 0.000
E30.1 Precocious puberty
0.512 0.488 0.000
E30.0 Delayed puberty
0.512 0.488 0.000
E32.9 Disease of thymus, unspecified
0.512 0.488 0.000
E32.8 Other diseases of thymus
0.512 0.488 0.000
E32.1 Abscess of thymus
0.512 0.488 0.000
E32.0 Persistent hyperplasia of thymus
0.512 0.488 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.512 0.488 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.512 0.488 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.512 0.488 0.000
E13.8 With unspecified complications
0.508 0.492 0.000
E13.7 With multiple complications
0.508 0.492 0.000
E13.6 With other specified complications
0.508 0.492 0.000
E13.5 With peripheral circulatory complications
0.508 0.492 0.000
E13.4 With neurological complications
0.508 0.492 0.000
E13.2 With renal complications
0.508 0.492 0.000
E13.1 With ketoacidosis
0.508 0.492 0.000
E13.0 With coma
0.508 0.492 0.000
E28 Ovarian dysfunction
0.505 0.495 0.000
E07.9 Disorder of thyroid, unspecified
0.495 0.505 0.000
E24.9 Cushing's syndrome, unspecified
0.490 0.510 0.000
E53.1 Pyridoxine deficiency
0.485 0.515 0.000
E53.0 Riboflavin deficiency
0.485 0.515 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.470 0.529 0.000
E45 Retarded development following protein-energy malnutrition
0.470 0.529 0.000
E43 Unspecified severe protein-energy malnutrition
0.470 0.529 0.000
E42 Marasmic kwashiorkor
0.470 0.529 0.000
E41 Nutritional marasmus
0.470 0.529 0.000
E40 Kwashiorkor
0.470 0.529 0.000
E29.9 Testicular dysfunction, unspecified
0.454 0.546 0.000
E29.8 Other testicular dysfunction
0.454 0.546 0.000
E29.0 Testicular hyperfunction
0.454 0.546 0.000
E55 Vitamin D deficiency
0.445 0.555 0.000
E34.9 Endocrine disorder, unspecified
0.441 0.558 0.000
E53.9 Vitamin B deficiency, unspecified
0.438 0.562 0.000
E11.8 With unspecified complications
0.437 0.563 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.565 0.435
E06.5 Other chronic thyroiditis
0.429 0.571 0.000
E11.1 With ketoacidosis
0.428 0.571 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.426 0.573 0.000
E22.8 Other hyperfunction of pituitary gland
0.426 0.573 0.000
K42.1 Umbilical hernia with gangrene
0.000 0.577 0.422
E06.4 Drug-induced thyroiditis
0.422 0.578 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.422 0.578 0.000
E06.1 Subacute thyroiditis
0.422 0.578 0.000
E06.0 Acute thyroiditis
0.422 0.578 0.000
E34.5 Androgen resistance syndrome
0.419 0.580 0.000
E34.4 Constitutional tall stature
0.419 0.580 0.000
E34.3 Short stature, not elsewhere classified
0.419 0.580 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.419 0.580 0.000
E34.1 Other hypersecretion of intestinal hormones
0.419 0.580 0.000
E13.9 Without complications
0.414 0.586 0.000
E26.9 Hyperaldosteronism, unspecified
0.413 0.587 0.000
E26.8 Other hyperaldosteronism
0.413 0.587 0.000
E26.1 Secondary hyperaldosteronism
0.413 0.587 0.000
E46 Unspecified protein-energy malnutrition
0.409 0.590 0.000
E65-E68 Obesity and other hyperalimentation
0.401 0.599 0.000
E34.8 Other specified endocrine disorders
0.400 0.599 0.000
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.604 0.396
E50.9 Vitamin A deficiency, unspecified
0.395 0.604 0.000
E50.8 Other manifestations of vitamin A deficiency
0.395 0.604 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.395 0.604 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.395 0.604 0.000
E50.5 Vitamin A deficiency with night blindness
0.395 0.604 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.395 0.604 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.395 0.604 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.395 0.604 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.395 0.604 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.395 0.604 0.000
E56.9 Vitamin deficiency, unspecified
0.395 0.604 0.000
E56.8 Deficiency of other vitamins
0.395 0.604 0.000
E56.1 Deficiency of vitamin K
0.395 0.604 0.000
E56.0 Deficiency of vitamin E
0.395 0.604 0.000
E63.9 Nutritional deficiency, unspecified
0.395 0.604 0.000
E63.8 Other specified nutritional deficiencies
0.395 0.604 0.000
E63.1 Imbalance of constituents of food intake
0.395 0.604 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.395 0.604 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.395 0.604 0.000
E64.8 Sequelae of other nutritional deficiencies
0.395 0.604 0.000
E64.3 Sequelae of rickets
0.395 0.604 0.000
E64.2 Sequelae of vitamin C deficiency
0.395 0.604 0.000
E64.1 Sequelae of vitamin A deficiency
0.395 0.604 0.000
E64.0 Sequelae of protein-energy malnutrition
0.395 0.604 0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.610 0.390
E51.9 Thiamine deficiency, unspecified
0.386 0.614 0.000
E51.8 Other manifestations of thiamine deficiency
0.386 0.614 0.000
E51.1 Beriberi
0.386 0.614 0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.618 0.382
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.618 0.382
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.618 0.382
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.618 0.382
E61.9 Deficiency of nutrient element, unspecified
0.376 0.624 0.000
E61.8 Deficiency of other specified nutrient elements
0.376 0.624 0.000
E61.7 Deficiency of multiple nutrient elements
0.376 0.624 0.000
E61.6 Vanadium deficiency
0.376 0.624 0.000
E61.5 Molybdenum deficiency
0.376 0.624 0.000
E61.4 Chromium deficiency
0.376 0.624 0.000
E61.3 Manganese deficiency
0.376 0.624 0.000
E61.0 Copper deficiency
0.376 0.624 0.000
E29.1 Testicular hypofunction
0.373 0.626 0.000
E51.2 Wernicke's encephalopathy
0.372 0.627 0.000
E27.8 Other specified disorders of adrenal gland
0.371 0.628 0.001
E61.1 Iron deficiency
0.369 0.630 0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.631 0.369
E06.3 Autoimmune thyroiditis
0.369 0.631 0.000
E28.9 Ovarian dysfunction, unspecified
0.362 0.638 0.000
E28.8 Other ovarian dysfunction
0.362 0.638 0.000
E28.1 Androgen excess
0.362 0.638 0.000
E28.0 Oestrogen excess
0.362 0.638 0.000
E28.3 Primary ovarian failure
0.358 0.641 0.000
E06.9 Thyroiditis, unspecified
0.356 0.644 0.000
E61.2 Magnesium deficiency
0.355 0.644 0.000
K45 Other abdominal hernia
0.001 0.658 0.341
E44.1 Mild protein-energy malnutrition
0.337 0.662 0.000
E44.0 Moderate protein-energy malnutrition
0.337 0.662 0.000
E55.0 Rickets, active
0.319 0.681 0.000
E11.2 With renal complications
0.300 0.700 0.000
E67 Other hyperalimentation
0.288 0.712 0.000
E68 Sequelae of hyperalimentation
0.288 0.712 0.000
E22.0 Acromegaly and pituitary gigantism
0.282 0.718 0.001
E34.0 Carcinoid syndrome
0.279 0.720 0.001
E26.0 Primary hyperaldosteronism
0.274 0.725 0.001
N40-N51 Diseases of male genital organs
0.000 0.736 0.264
E65 Localised adiposity
0.262 0.738 0.000
N41 Inflammatory diseases of prostate
0.000 0.746 0.254
K45.1 Other specified abdominal hernia with gangrene
0.001 0.754 0.245
N41.1 Chronic prostatitis
0.000 0.756 0.244
N42 Other disorders of prostate
0.000 0.765 0.235
N41.0 Acute prostatitis
0.000 0.775 0.225
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.779 0.221
E55.9 Vitamin D deficiency, unspecified
0.212 0.788 0.000
N44 Torsion of testis
0.000 0.789 0.211
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.207 0.792 0.001
E67.8 Other specified hyperalimentation
0.206 0.793 0.000
E67.3 Hypervitaminosis D
0.206 0.793 0.000
E67.2 Megavitamin-B6 syndrome
0.206 0.793 0.000
E67.1 Hypercarotenaemia
0.206 0.793 0.000
E67.0 Hypervitaminosis A
0.206 0.793 0.000
N42.8 Other specified disorders of prostate
0.000 0.794 0.206
N45 Orchitis and epididymitis
0.000 0.794 0.206
N42.1 Congestion and haemorrhage of prostate
0.000 0.795 0.205
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.811 0.189
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.813 0.187
N46 Male infertility
0.000 0.814 0.186
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.001 0.814 0.185
N41.3 Prostatocystitis
0.000 0.817 0.182
N41.2 Abscess of prostate
0.000 0.817 0.182
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.822 0.178
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.825 0.175
K43 Ventral hernia
0.000 0.826 0.174
N32.0 Bladder-neck obstruction
0.000 0.827 0.173
H36.0 Diabetic retinopathy
0.173 0.827 0.000
N39 Other disorders of urinary system
0.000 0.829 0.171
N39.8 Other specified disorders of urinary system
0.000 0.829 0.171
N42.0 Calculus of prostate
0.000 0.830 0.170
N42.3 Dysplasia of prostate
0.000 0.831 0.169
N39.9 Disorder of urinary system, unspecified
0.000 0.835 0.165
N32 Other disorders of bladder
0.000 0.838 0.162
E28.2 Polycystic ovarian syndrome
0.161 0.838 0.001
N30-N39 Other diseases of urinary system
0.000 0.839 0.161
N39.0 Urinary tract infection, site not specified
0.000 0.841 0.159
N36 Other disorders of urethra
0.000 0.844 0.156
N42.9 Disorder of prostate, unspecified
0.000 0.846 0.154
H36 Retinal disorders in diseases classified elsewhere
0.153 0.847 0.000
N42.2 Atrophy of prostate
0.000 0.848 0.151
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.849 0.151
E83 Disorders of mineral metabolism
0.020 0.850 0.129
N41.8 Other inflammatory diseases of prostate
0.000 0.851 0.148
N36.2 Urethral caruncle
0.000 0.852 0.148
E04 Other non-toxic goitre
0.145 0.855 0.000
H30-H36 Disorders of choroid and retina
0.139 0.861 0.000
H34 Retinal vascular occlusions
0.137 0.863 0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.864 0.136
N51.2 Balanitis in diseases classified elsewhere
0.000 0.864 0.136
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.864 0.136
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.864 0.136
M35.0 Sicca syndrome [Sjogren]
0.135 0.865 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.866 0.134
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.866 0.134
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.866 0.134
N34 Urethritis and urethral syndrome
0.000 0.866 0.133
H34.8 Other retinal vascular occlusions
0.133 0.867 0.000
N36.3 Prolapsed urethral mucosa
0.000 0.867 0.133
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.001 0.867 0.131
N32.1 Vesicointestinal fistula
0.000 0.869 0.131
N36.0 Urethral fistula
0.000 0.870 0.130
N32.2 Vesical fistula, not elsewhere classified
0.000 0.872 0.128
K90-K93 Other diseases of the digestive system
0.122 0.873 0.004
N39.3 Stress incontinence
0.000 0.875 0.125
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.875 0.125
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.875 0.125
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.875 0.125
K43.4 Parastomal hernia with gangrene
0.000 0.875 0.125
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.875 0.125
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.875 0.125
K43.1 Ventral hernia with gangrene
0.000 0.875 0.125
H33 Retinal detachments and breaks
0.125 0.875 0.000
N39.2 Orthostatic proteinuria, unspecified
0.000 0.877 0.123
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.880 0.120
H33.0 Retinal detachment with retinal break
0.120 0.880 0.000
N32.4 Rupture of bladder, nontraumatic
0.000 0.883 0.117
N37 Urethral disorders in diseases classified elsewhere
0.000 0.884 0.115
N33 Bladder disorders in diseases classified elsewhere
0.000 0.884 0.115
N36.9 Urethral disorder, unspecified
0.000 0.885 0.115
H34.2 Other retinal artery occlusions
0.115 0.885 0.000
E83.3 Disorders of phosphorus metabolism
0.007 0.887 0.106
N36.1 Urethral diverticulum
0.000 0.887 0.113
N34.2 Other urethritis
0.000 0.887 0.113
H36.8 Other retinal disorders in diseases classified elsewhere
0.110 0.890 0.000
N32.8 Other specified disorders of bladder
0.000 0.891 0.109
H33.2 Serous retinal detachment
0.109 0.891 0.000
H34.1 Central retinal artery occlusion
0.108 0.892 0.000
N32.3 Diverticulum of bladder
0.000 0.892 0.108
E83.9 Disorder of mineral metabolism, unspecified
0.015 0.892 0.093
E83.8 Other disorders of mineral metabolism
0.015 0.892 0.093
E83.2 Disorders of zinc metabolism
0.015 0.892 0.093
E83.0 Disorders of copper metabolism
0.015 0.892 0.093
N49.2 Inflammatory disorders of scrotum
0.000 0.894 0.106
E04.8 Other specified non-toxic goitre
0.104 0.896 0.000
H33.4 Traction detachment of retina
0.104 0.896 0.000
N34.3 Urethral syndrome, unspecified
0.000 0.899 0.101
E11.9 Without complications
0.101 0.899 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.100 0.900 0.000
H34.0 Transient retinal artery occlusion
0.099 0.901 0.000
H30 Chorioretinal inflammation
0.097 0.903 0.000
N34.0 Urethral abscess
0.000 0.904 0.096
H34.9 Retinal vascular occlusion, unspecified
0.095 0.905 0.000
N43 Hydrocele and spermatocele
0.000 0.908 0.092
N34.1 Nonspecific urethritis
0.000 0.908 0.092
N39.1 Persistent proteinuria, unspecified
0.000 0.909 0.091
K93 Disorders of other digestive organs in diseases classified elsewhere
0.088 0.909 0.003
K42.9 Umbilical hernia without obstruction or gangrene
0.000 0.909 0.091
E04.0 Non-toxic diffuse goitre
0.090 0.910 0.000
E04.9 Non-toxic goitre, unspecified
0.088 0.912 0.000
N33.8 Bladder disorders in other diseases classified elsewhere
0.000 0.917 0.083
N33.0 Tuberculous cystitis
0.000 0.917 0.083
N37.8 Other urethral disorders in diseases classified elsewhere
0.000 0.917 0.083
N37.0 Urethritis in diseases classified elsewhere
0.000 0.917 0.083
H31 Other disorders of choroid
0.083 0.917 0.000
E11.4 With neurological complications
0.078 0.920 0.002
H35 Other retinal disorders
0.079 0.921 0.000
N36.8 Other specified disorders of urethra
0.000 0.921 0.079
H33.1 Retinoschisis and retinal cysts
0.078 0.922 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.074 0.926 0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.072 0.928 0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.072 0.928 0.000
K75.4 Autoimmune hepatitis
0.071 0.929 0.000
N35 Urethral stricture
0.000 0.929 0.071
H30.8 Other chorioretinal inflammations
0.070 0.930 0.000
H30.2 Posterior cyclitis
0.070 0.930 0.000
H30.1 Disseminated chorioretinal inflammation
0.070 0.930 0.000
H30.0 Focal chorioretinal inflammation
0.070 0.930 0.000
H35.8 Other specified retinal disorders
0.069 0.931 0.000
H30.9 Chorioretinal inflammation, unspecified
0.067 0.933 0.000
N43.2 Other hydrocele
0.000 0.934 0.066
N43.1 Infected hydrocele
0.000 0.934 0.066
N43.0 Encysted hydrocele
0.000 0.934 0.066
M35 Other systemic involvement of connective tissue
0.066 0.934 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.063 0.934 0.002
K93.1 Megacolon in Chagas' disease
0.063 0.934 0.002
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.063 0.934 0.002
H35.4 Peripheral retinal degeneration
0.064 0.936 0.000
H35.2 Other proliferative retinopathy
0.064 0.936 0.000
K91.4 Colostomy and enterostomy malfunction
0.061 0.939 0.000
K91.3 Postoperative intestinal obstruction
0.061 0.939 0.000
H33.3 Retinal breaks without detachment
0.060 0.940 0.000
H31.9 Disorder of choroid, unspecified
0.059 0.940 0.000
H31.4 Choroidal detachment
0.059 0.940 0.000
H31.3 Choroidal haemorrhage and rupture
0.059 0.940 0.000
H31.2 Hereditary choroidal dystrophy
0.059 0.940 0.000
H35.0 Background retinopathy and retinal vascular changes
0.058 0.942 0.000
K75 Other inflammatory liver diseases
0.057 0.943 0.000
H35.1 Retinopathy of prematurity
0.057 0.943 0.000
H31.0 Chorioretinal scars
0.057 0.943 0.000
E83.4 Disorders of magnesium metabolism
0.013 0.944 0.043
H35.7 Separation of retinal layers
0.056 0.944 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.056 0.944 0.000
K75.8 Other specified inflammatory liver diseases
0.055 0.945 0.000
H31.1 Choroidal degeneration
0.054 0.945 0.000
K91.5 Postcholecystectomy syndrome
0.053 0.946 0.000
H35.6 Retinal haemorrhage
0.053 0.947 0.000
H31.8 Other specified disorders of choroid
0.053 0.947 0.000
K91.1 Postgastric surgery syndromes
0.052 0.947 0.000
M35.1 Other overlap syndromes
0.052 0.948 0.000
E70-E90 Metabolic disorders
0.050 0.948 0.002
N43.4 Spermatocele
0.000 0.949 0.051
N35.1 Postinfective urethral stricture, not elsewhere classified
0.000 0.949 0.051
N35.0 Posttraumatic urethral stricture
0.000 0.949 0.051
E66 Obesity
0.051 0.949 0.000
M35.2 Behcet's disease
0.050 0.950 0.000
N35.8 Other urethral stricture
0.000 0.951 0.049
M35.9 Systemic involvement of connective tissue, unspecified
0.047 0.953 0.000
M35.8 Other specified systemic involvement of connective tissue
0.047 0.953 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.047 0.953 0.000
M35.5 Multifocal fibrosclerosis
0.047 0.953 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.047 0.953 0.000
N50 Other disorders of male genital organs
0.000 0.953 0.047
K75.9 Inflammatory liver disease, unspecified
0.046 0.954 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.045 0.955 0.001
Chapter XIV Diseases of the genitourinary system
0.000 0.956 0.044
H35.5 Hereditary retinal dystrophy
0.044 0.956 0.000
M35.3 Polymyalgia rheumatica
0.044 0.956 0.000
M35.7 Hypermobility syndrome
0.042 0.958 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.041 0.958 0.000
E84 Cystic fibrosis
0.040 0.959 0.001
K75.3 Granulomatous hepatitis, not elsewhere classified
0.041 0.959 0.000
K75.2 Nonspecific reactive hepatitis
0.041 0.959 0.000
K75.1 Phlebitis of portal vein
0.041 0.959 0.000
E74 Other disorders of carbohydrate metabolism
0.040 0.959 0.001
K43.0 Ventral hernia with obstruction, without gangrene
0.001 0.960 0.039
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.036 0.962 0.001
H35.9 Retinal disorder, unspecified
0.037 0.962 0.000
N84.1 Polyp of cervix uteri
0.000 0.963 0.037
E77 Disorders of glycoprotein metabolism
0.036 0.963 0.001
E76 Disorders of glycosaminoglycan metabolism
0.036 0.963 0.001
E72 Other disorders of amino-acid metabolism
0.036 0.963 0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.036 0.963 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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