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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs203876
log Bayes Factor = 85.0697
Chromosome 6   position 28,046,673  (GRCh37) Explore rs203876 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
E10.3 With ophthalmic complications
0.995 0.005 0.000
K40 Inguinal hernia
0.000 0.007 0.993
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.993 0.007 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.008 0.992
E14 Unspecified diabetes mellitus
0.991 0.009 0.000
E16 Other disorders of pancreatic internal secretion
0.989 0.011 0.000
E16.2 Hypoglycaemia, unspecified
0.984 0.016 0.000
E00-E07 Disorders of thyroid gland
0.983 0.017 0.000
E20-E35 Disorders of other endocrine glands
0.975 0.025 0.000
E10.1 With ketoacidosis
0.974 0.026 0.000
E27 Other disorders of adrenal gland
0.958 0.042 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.954 0.046 0.000
E27.1 Primary adrenocortical insufficiency
0.952 0.048 0.000
E14.9 Without complications
0.947 0.053 0.000
E05.9 Thyrotoxicosis, unspecified
0.945 0.055 0.000
N40 Hyperplasia of prostate
0.000 0.060 0.940
N41 Inflammatory diseases of prostate
0.000 0.073 0.927
N40-N51 Diseases of male genital organs
0.000 0.076 0.924
E03 Other hypothyroidism
0.917 0.083 0.000
N41.0 Acute prostatitis
0.000 0.085 0.915
E10.4 With neurological complications
0.915 0.085 0.000
E14.3 With ophthalmic complications
0.909 0.091 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.099 0.901
E07 Other disorders of thyroid
0.894 0.106 0.000
E10.2 With renal complications
0.888 0.112 0.000
E03.9 Hypothyroidism, unspecified
0.884 0.116 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.852 0.148 0.000
E23 Hypofunction and other disorders of pituitary gland
0.848 0.152 0.000
E14.4 With neurological complications
0.840 0.160 0.000
E20 Hypoparathyroidism
0.827 0.173 0.000
E24 Cushing's syndrome
0.826 0.174 0.000
N41.1 Chronic prostatitis
0.000 0.175 0.825
N42 Other disorders of prostate
0.000 0.183 0.817
E10.6 With other specified complications
0.814 0.186 0.000
N46 Male infertility
0.000 0.188 0.812
K90 Intestinal malabsorption
0.789 0.211 0.000
E10.5 With peripheral circulatory complications
0.788 0.212 0.000
E10.7 With multiple complications
0.776 0.224 0.000
E07.9 Disorder of thyroid, unspecified
0.773 0.227 0.000
E10.0 With coma
0.771 0.229 0.000
E07.8 Other specified disorders of thyroid
0.759 0.241 0.000
E31 Polyglandular dysfunction
0.758 0.242 0.000
N42.8 Other specified disorders of prostate
0.000 0.243 0.757
E23.2 Diabetes insipidus
0.745 0.255 0.000
N44 Torsion of testis
0.000 0.257 0.743
E27.9 Disorder of adrenal gland, unspecified
0.740 0.260 0.000
E14.1 With ketoacidosis
0.737 0.263 0.000
E14.5 With peripheral circulatory complications
0.732 0.268 0.000
E25 Adrenogenital disorders
0.731 0.269 0.000
E27.2 Addisonian crisis
0.724 0.276 0.000
E20.9 Hypoparathyroidism, unspecified
0.721 0.279 0.000
E50-E64 Other nutritional deficiencies
0.720 0.279 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E14.6 With other specified complications
0.717 0.283 0.000
E14.2 Withrenal complications
0.714 0.286 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.288 0.712
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.288 0.712
E15 Nondiabetic hypoglycaemic coma
0.712 0.288 0.000
E14.7 With multiple complications
0.710 0.290 0.000
E14.0 With coma
0.710 0.290 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.710 0.290 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.709 0.291 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.709 0.291 0.000
E16.4 Abnormal secretion of gastrin
0.709 0.291 0.000
E16.3 Increased secretion of glucagon
0.709 0.291 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.705 0.295 0.000
E00 Congenital iodine-deficiency syndrome
0.705 0.295 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.703 0.297 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.700 0.300 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.699 0.301 0.000
E32 Diseases of thymus
0.699 0.301 0.000
E30 Disorders of puberty, not elsewhere classified
0.699 0.301 0.000
K90.9 Intestinal malabsorption, unspecified
0.689 0.310 0.000
E27.5 Adrenomedullary hyperfunction
0.687 0.313 0.000
E27.0 Other adrenocortical overactivity
0.687 0.313 0.000
E05.5 Thyroid crisis or storm
0.684 0.316 0.000
E05.4 Thyrotoxicosis factitia
0.684 0.316 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.684 0.316 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.684 0.316 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.675 0.325 0.000
E24.2 Drug-induced Cushing's syndrome
0.674 0.326 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.330 0.670
N42.0 Calculus of prostate
0.000 0.333 0.667
E06 Thyroiditis
0.666 0.334 0.000
N41.3 Prostatocystitis
0.000 0.335 0.664
N41.2 Abscess of prostate
0.000 0.335 0.664
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.336 0.664
E14.8 With unspecified complications
0.662 0.338 0.000
N48 Other disorders of penis
0.000 0.342 0.658
E03.5 Myxoedema coma
0.658 0.342 0.000
E03.4 Atrophy of thyroid (acquired)
0.658 0.342 0.000
E03.3 Postinfectious hypothyroidism
0.658 0.342 0.000
E03.1 Congenital hypothyroidism without goitre
0.658 0.342 0.000
E23.0 Hypopituitarism
0.655 0.345 0.000
N48.4 Impotence of organic origin
0.000 0.347 0.653
E29 Testicular dysfunction
0.650 0.350 0.000
E16.1 Other hypoglycaemia
0.645 0.355 0.000
E40-E46 Malnutrition
0.643 0.357 0.000
E07.1 Dyshormogenetic goitre
0.641 0.359 0.000
E07.0 Hypersecretion of calcitonin
0.641 0.359 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.639 0.361 0.000
E24.0 Pituitary-dependent Cushing's disease
0.635 0.365 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.635 0.365 0.000
E10.8 With unspecified complications
0.634 0.366 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.371 0.629
E05.8 Other thyrotoxicosis
0.627 0.373 0.000
E24.8 Other Cushing's syndrome
0.624 0.375 0.000
N45 Orchitis and epididymitis
0.000 0.379 0.621
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.608 0.392 0.000
E23.1 Drug-induced hypopituitarism
0.608 0.392 0.000
E31.0 Autoimmune polyglandular failure
0.602 0.398 0.000
E28 Ovarian dysfunction
0.602 0.398 0.000
E23.7 Disorder of pituitary gland, unspecified
0.602 0.398 0.000
E24.9 Cushing's syndrome, unspecified
0.596 0.404 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.406 0.594
E20.8 Other hypoparathyroidism
0.593 0.407 0.000
E20.1 Pseudohypoparathyroidism
0.593 0.407 0.000
E20.0 Idiopathic hypoparathyroidism
0.593 0.407 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.592 0.407 0.000
E24.3 Ectopic ACTH syndrome
0.592 0.407 0.000
E24.1 Nelson's syndrome
0.592 0.407 0.000
E53 Deficiency of other B group vitamins
0.592 0.408 0.000
K90.8 Other intestinal malabsorption
0.591 0.409 0.000
E23.6 Other disorders of pituitary gland
0.588 0.412 0.000
N42.3 Dysplasia of prostate
0.000 0.414 0.586
E02 Subclinical iodine-deficiency hypothyroidism
0.582 0.417 0.000
E26 Hyperaldosteronism
0.579 0.420 0.000
N48.2 Other inflammatory disorders of penis
0.000 0.423 0.577
K90.3 Pancreatic steatorrhoea
0.566 0.434 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.566 0.434 0.000
K90.1 Tropical sprue
0.566 0.434 0.000
N41.8 Other inflammatory diseases of prostate
0.000 0.439 0.561
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.556 0.444 0.000
E61 Deficiency of other nutrient elements
0.556 0.444 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.447 0.553
E34 Other endocrine disorders
0.553 0.447 0.000
E31.9 Polyglandular dysfunction, unspecified
0.543 0.457 0.000
E31.8 Other polyglandular dysfunction
0.543 0.457 0.000
E31.1 Polyglandular hyperfunction
0.543 0.457 0.000
N42.2 Atrophy of prostate
0.000 0.462 0.538
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.462 0.538
E11 Non-insulin-dependent diabetes mellitus
0.536 0.464 0.000
E13 Other specified diabetes mellitus
0.529 0.470 0.000
E25.9 Adrenogenital disorder, unspecified
0.524 0.476 0.000
E25.8 Other adrenogenital disorders
0.524 0.476 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.522 0.478 0.000
E03.8 Other specified hypothyroidism
0.519 0.480 0.000
E11.5 With peripheral circulatory complications
0.519 0.481 0.000
E51 Thiamine deficiency
0.517 0.483 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.517 0.483 0.000
E63 Other nutritional deficiencies
0.517 0.483 0.000
E56 Other vitamin deficiencies
0.517 0.483 0.000
E50 Vitamin A deficiency
0.517 0.483 0.000
E60 Dietary zinc deficiency
0.517 0.483 0.000
E59 Dietary selenium deficiency
0.517 0.483 0.000
E54 Ascorbic acid deficiency
0.517 0.483 0.000
E52 Niacin deficiency [pellagra]
0.517 0.483 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E06.5 Other chronic thyroiditis
0.512 0.488 0.000
E58 Dietary calcium deficiency
0.509 0.491 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.505 0.495 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.505 0.495 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.505 0.495 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.505 0.495 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.505 0.495 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.505 0.495 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.505 0.495 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.505 0.495 0.000
N48.1 Balanoposthitis
0.000 0.496 0.504
E30.9 Disorder of puberty, unspecified
0.501 0.499 0.000
E30.8 Other disorders of puberty
0.501 0.499 0.000
E30.1 Precocious puberty
0.501 0.499 0.000
E30.0 Delayed puberty
0.501 0.499 0.000
E32.9 Disease of thymus, unspecified
0.501 0.499 0.000
E32.8 Other diseases of thymus
0.501 0.499 0.000
E32.1 Abscess of thymus
0.501 0.499 0.000
E32.0 Persistent hyperplasia of thymus
0.501 0.499 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.501 0.499 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.501 0.499 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.501 0.499 0.000
E53.8 Deficiency of other specified B group vitamins
0.482 0.518 0.000
E06.4 Drug-induced thyroiditis
0.477 0.523 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.477 0.523 0.000
E06.1 Subacute thyroiditis
0.477 0.523 0.000
E06.0 Acute thyroiditis
0.477 0.523 0.000
E29.9 Testicular dysfunction, unspecified
0.466 0.534 0.000
E29.8 Other testicular dysfunction
0.466 0.534 0.000
E29.0 Testicular hyperfunction
0.466 0.534 0.000
E11.3 With ophthalmic complications
0.466 0.534 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.461 0.539 0.000
E45 Retarded development following protein-energy malnutrition
0.461 0.539 0.000
E43 Unspecified severe protein-energy malnutrition
0.461 0.539 0.000
E42 Marasmic kwashiorkor
0.461 0.539 0.000
E41 Nutritional marasmus
0.461 0.539 0.000
E40 Kwashiorkor
0.461 0.539 0.000
K40-K46 Hernia
0.000 0.548 0.452
E53.9 Vitamin B deficiency, unspecified
0.451 0.549 0.000
E61.1 Iron deficiency
0.448 0.552 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.552 0.448
E22 Hyperfunction of pituitary gland
0.447 0.553 0.000
E06.9 Thyroiditis, unspecified
0.439 0.561 0.000
E06.3 Autoimmune thyroiditis
0.434 0.565 0.000
E28.3 Primary ovarian failure
0.433 0.567 0.000
E28.9 Ovarian dysfunction, unspecified
0.432 0.568 0.000
E28.8 Other ovarian dysfunction
0.432 0.568 0.000
E28.1 Androgen excess
0.432 0.568 0.000
E28.0 Oestrogen excess
0.432 0.568 0.000
K41 Femoral hernia
0.000 0.572 0.428
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.574 0.426
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.574 0.426
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.574 0.426
E53.1 Pyridoxine deficiency
0.424 0.576 0.000
E53.0 Riboflavin deficiency
0.424 0.576 0.000
N48.5 Ulcer of penis
0.000 0.580 0.419
E29.1 Testicular hypofunction
0.416 0.583 0.000
E26.9 Hyperaldosteronism, unspecified
0.415 0.584 0.000
E26.8 Other hyperaldosteronism
0.415 0.584 0.000
E26.1 Secondary hyperaldosteronism
0.415 0.584 0.000
E21.4 Other specified disorders of parathyroid gland
0.413 0.587 0.000
E34.8 Other specified endocrine disorders
0.409 0.590 0.000
E11.6 With other specified complications
0.407 0.593 0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.599 0.400
E61.9 Deficiency of nutrient element, unspecified
0.398 0.601 0.000
E61.8 Deficiency of other specified nutrient elements
0.398 0.601 0.000
E61.7 Deficiency of multiple nutrient elements
0.398 0.601 0.000
E61.6 Vanadium deficiency
0.398 0.601 0.000
E61.5 Molybdenum deficiency
0.398 0.601 0.000
E61.4 Chromium deficiency
0.398 0.601 0.000
E61.3 Manganese deficiency
0.398 0.601 0.000
E61.0 Copper deficiency
0.398 0.601 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.603 0.397
E34.5 Androgen resistance syndrome
0.396 0.603 0.000
E34.4 Constitutional tall stature
0.396 0.603 0.000
E34.3 Short stature, not elsewhere classified
0.396 0.603 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.396 0.603 0.000
E34.1 Other hypersecretion of intestinal hormones
0.396 0.603 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.391 0.608 0.001
E46 Unspecified protein-energy malnutrition
0.388 0.612 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.614 0.386
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.614 0.386
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.614 0.386
E11.7 With multiple complications
0.384 0.615 0.000
E61.2 Magnesium deficiency
0.384 0.616 0.000
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.616 0.383
E21.2 Other hyperparathyroidism
0.382 0.618 0.000
E13.8 With unspecified complications
0.380 0.620 0.000
E13.7 With multiple complications
0.380 0.620 0.000
E13.6 With other specified complications
0.380 0.620 0.000
E13.5 With peripheral circulatory complications
0.380 0.620 0.000
E13.4 With neurological complications
0.380 0.620 0.000
E13.2 With renal complications
0.380 0.620 0.000
E13.1 With ketoacidosis
0.380 0.620 0.000
E13.0 With coma
0.380 0.620 0.000
K43 Ventral hernia
0.000 0.623 0.377
E13.3 With ophthalmic complications
0.374 0.626 0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.628 0.372
E51.2 Wernicke's encephalopathy
0.372 0.628 0.000
E51.9 Thiamine deficiency, unspecified
0.371 0.629 0.000
E51.8 Other manifestations of thiamine deficiency
0.371 0.629 0.000
E51.1 Beriberi
0.371 0.629 0.000
E50.9 Vitamin A deficiency, unspecified
0.370 0.629 0.000
E50.8 Other manifestations of vitamin A deficiency
0.370 0.629 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.370 0.629 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.370 0.629 0.000
E50.5 Vitamin A deficiency with night blindness
0.370 0.629 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.370 0.629 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.370 0.629 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.370 0.629 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.370 0.629 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.370 0.629 0.000
E56.9 Vitamin deficiency, unspecified
0.370 0.629 0.000
E56.8 Deficiency of other vitamins
0.370 0.629 0.000
E56.1 Deficiency of vitamin K
0.370 0.629 0.000
E56.0 Deficiency of vitamin E
0.370 0.629 0.000
E63.9 Nutritional deficiency, unspecified
0.370 0.629 0.000
E63.8 Other specified nutritional deficiencies
0.370 0.629 0.000
E63.1 Imbalance of constituents of food intake
0.370 0.629 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.370 0.629 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.370 0.629 0.000
E64.8 Sequelae of other nutritional deficiencies
0.370 0.629 0.000
E64.3 Sequelae of rickets
0.370 0.629 0.000
E64.2 Sequelae of vitamin C deficiency
0.370 0.629 0.000
E64.1 Sequelae of vitamin A deficiency
0.370 0.629 0.000
E64.0 Sequelae of protein-energy malnutrition
0.370 0.629 0.000
N48.3 Priapism
0.000 0.633 0.366
E11.0 With coma
0.366 0.634 0.000
E34.0 Carcinoid syndrome
0.362 0.637 0.000
E11.1 With ketoacidosis
0.362 0.638 0.000
N51.2 Balanitis in diseases classified elsewhere
0.000 0.642 0.357
K43.9 Ventral hernia without obstruction or gangrene
0.000 0.643 0.357
E21.3 Hyperparathyroidism, unspecified
0.350 0.650 0.000
E55 Vitamin D deficiency
0.343 0.656 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.341 0.659 0.000
E28.2 Polycystic ovarian syndrome
0.333 0.667 0.000
E44.1 Mild protein-energy malnutrition
0.330 0.669 0.000
E44.0 Moderate protein-energy malnutrition
0.330 0.669 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.323 0.677 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.320 0.679 0.000
E22.8 Other hyperfunction of pituitary gland
0.320 0.679 0.000
N43 Hydrocele and spermatocele
0.000 0.681 0.319
N50 Other disorders of male genital organs
0.000 0.688 0.312
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.693 0.307
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.693 0.307
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.693 0.307
K46 Unspecified abdominal hernia
0.000 0.694 0.306
N48.0 Leukoplakia of penis
0.000 0.697 0.303
E22.1 Hyperprolactinaemia
0.299 0.701 0.000
E26.0 Primary hyperaldosteronism
0.296 0.703 0.000
E11.8 With unspecified complications
0.292 0.708 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.711 0.289
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.712 0.288
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.283 0.717 0.000
E34.9 Endocrine disorder, unspecified
0.282 0.718 0.000
E21.0 Primary hyperparathyroidism
0.279 0.721 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.729 0.270
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.729 0.270
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.729 0.270
K43.4 Parastomal hernia with gangrene
0.000 0.729 0.270
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.729 0.270
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.729 0.270
K43.1 Ventral hernia with gangrene
0.000 0.729 0.270
E65-E68 Obesity and other hyperalimentation
0.267 0.733 0.000
N49.2 Inflammatory disorders of scrotum
0.000 0.734 0.265
E27.8 Other specified disorders of adrenal gland
0.262 0.736 0.002
N50.9 Disorder of male genital organs, unspecified
0.000 0.743 0.257
E55.0 Rickets, active
0.246 0.753 0.000
N50.0 Atrophy of testis
0.000 0.755 0.245
N42.9 Disorder of prostate, unspecified
0.000 0.760 0.240
K44 Diaphragmatic hernia
0.000 0.771 0.229
N43.2 Other hydrocele
0.000 0.771 0.229
N43.1 Infected hydrocele
0.000 0.771 0.229
N43.0 Encysted hydrocele
0.000 0.771 0.229
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.773 0.227
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.781 0.219
N48.9 Disorder of penis, unspecified
0.001 0.793 0.206
E13.9 Without complications
0.205 0.795 0.001
E22.0 Acromegaly and pituitary gigantism
0.198 0.801 0.000
K42 Umbilical hernia
0.000 0.802 0.198
K45 Other abdominal hernia
0.000 0.804 0.196
E67 Other hyperalimentation
0.191 0.808 0.000
E68 Sequelae of hyperalimentation
0.191 0.808 0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.809 0.191
E11.2 With renal complications
0.184 0.815 0.000
K44.1 Diaphragmatic hernia with gangrene
0.000 0.821 0.179
R30.0 Dysuria
0.000 0.835 0.165
R30 Pain associated with micturition
0.000 0.836 0.164
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.837 0.163
R30-R39 Symptoms and signs involving the urinary system
0.000 0.838 0.162
N43.4 Spermatocele
0.001 0.855 0.145
K42.1 Umbilical hernia with gangrene
0.000 0.858 0.142
K45.1 Other specified abdominal hernia with gangrene
0.000 0.859 0.140
E67.8 Other specified hyperalimentation
0.137 0.862 0.000
E67.3 Hypervitaminosis D
0.137 0.862 0.000
E67.2 Megavitamin-B6 syndrome
0.137 0.862 0.000
E67.1 Hypercarotenaemia
0.137 0.862 0.000
E67.0 Hypervitaminosis A
0.137 0.862 0.000
R30.1 Vesical tenesmus
0.000 0.869 0.130
R47.0 Dysphasia and aphasia
0.127 0.873 0.000
N48.6 Balanitis xerotica obliterans
0.000 0.874 0.126
E04 Other non-toxic goitre
0.126 0.874 0.000
R30.9 Painful micturition, unspecified
0.000 0.878 0.122
E83 Disorders of mineral metabolism
0.024 0.881 0.095
N48.8 Other specified disorders of penis
0.000 0.885 0.114
R36 Urethral discharge
0.000 0.889 0.111
K42.9 Umbilical hernia without obstruction or gangrene
0.000 0.891 0.109
K43.0 Ventral hernia with obstruction, without gangrene
0.000 0.898 0.102
E65 Localised adiposity
0.100 0.899 0.001
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.001 0.903 0.097
N43.3 Hydrocele, unspecified
0.000 0.906 0.094
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.001 0.906 0.093
R34 Anuria and oliguria
0.000 0.908 0.092
E04.8 Other specified non-toxic goitre
0.090 0.910 0.000
E11.4 With neurological complications
0.089 0.910 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.017 0.914 0.068
E83.8 Other disorders of mineral metabolism
0.017 0.914 0.068
E83.2 Disorders of zinc metabolism
0.017 0.914 0.068
E83.0 Disorders of copper metabolism
0.017 0.914 0.068
R35 Polyuria
0.000 0.915 0.085
K42.0 Umbilical hernia with obstruction, without gangrene
0.000 0.916 0.084
E83.3 Disorders of phosphorus metabolism
0.009 0.918 0.073
E04.0 Non-toxic diffuse goitre
0.080 0.920 0.000
E70-E90 Metabolic disorders
0.076 0.923 0.001
E55.9 Vitamin D deficiency, unspecified
0.073 0.926 0.000
R47 Speech disturbances, not elsewhere classified
0.073 0.927 0.000
I83 Varicose veins of lower extremities
0.000 0.927 0.073
E73 Lactose intolerance
0.066 0.933 0.001
R47.1 Dysarthria and anarthria
0.064 0.936 0.000
E84 Cystic fibrosis
0.061 0.938 0.001
E73.9 Lactose intolerance, unspecified
0.060 0.940 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.058 0.941 0.001
E88 Other metabolic disorders
0.058 0.941 0.001
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.058 0.942 0.000
E79 Disorders of purine and pyrimidine metabolism
0.054 0.944 0.001
E77 Disorders of glycoprotein metabolism
0.054 0.944 0.001
E76 Disorders of glycosaminoglycan metabolism
0.054 0.944 0.001
E72 Other disorders of amino-acid metabolism
0.054 0.944 0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.054 0.944 0.001
E70 Disorders of aromatic amino-acid metabolism
0.054 0.944 0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.054 0.944 0.001
E04.1 Non-toxic single thyroid nodule
0.054 0.945 0.000
E78.1 Pure hyperglyceridaemia
0.053 0.946 0.000
E84.9 Cystic fibrosis, unspecified
0.050 0.949 0.001
E78.6 Lipoprotein deficiency
0.051 0.949 0.000
E74 Other disorders of carbohydrate metabolism
0.049 0.949 0.001
E85 Amyloidosis
0.048 0.951 0.001
E73.8 Other lactose intolerance
0.048 0.952 0.001
E73.1 Secondary lactase deficiency
0.048 0.952 0.001
E73.0 Congenital lactase deficiency
0.048 0.952 0.001
K90-K93 Other diseases of the digestive system
0.048 0.952 0.000
E88.2 Lipomatosis, not elsewhere classified
0.048 0.952 0.000
E88.9 Metabolic disorder, unspecified
0.047 0.953 0.000
E78.2 Mixed hyperlipidaemia
0.047 0.953 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.955 0.045
N50.1 Vascular disorders of male genital organs
0.000 0.955 0.045
E75.2 Other sphingolipidosis
0.044 0.955 0.001
E84.8 Cystic fibrosis with other manifestations
0.044 0.955 0.001
E84.1 Cystic fibrosis with intestinal manifestations
0.044 0.955 0.001
E84.0 Cystic fibrosis with pulmonary manifestations
0.044 0.955 0.001
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.956 0.043
E75.5 Other lipid storage disorders
0.043 0.957 0.001
R47.8 Other and unspecified speech disturbances
0.042 0.958 0.000
E75.6 Lipid storage disorder, unspecified
0.042 0.958 0.001
E75.4 Neuronal ceroid lipofuscinosis
0.042 0.958 0.001
E75.3 Sphingolipidosis, unspecified
0.042 0.958 0.001
E75.1 Other gangliosidosis
0.042 0.958 0.001
E75.0 GM2 gangliosidosis
0.042 0.958 0.001
E78.3 Hyperchylomicronaemia
0.041 0.958 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.040 0.959 0.000
E88.3 Tumour lysis syndrome
0.040 0.960 0.001
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.039 0.960 0.001
E70.8 Other disorders of aromatic amino-acid metabolism
0.039 0.960 0.001
E70.3 Albinism
0.039 0.960 0.001
E70.2 Disorders of tyrosine metabolism
0.039 0.960 0.001
E70.1 Other hyperphenylalaninaemias
0.039 0.960 0.001
E70.0 Classical phenylketonuria
0.039 0.960 0.001
E71.3 Disorders of fatty-acid metabolism
0.039 0.960 0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.039 0.960 0.001
E71.1 Other disorders of branched-chain amino-acid metabolism
0.039 0.960 0.001
E71.0 Maple-syrup-urine disease
0.039 0.960 0.001
E72.9 Disorder of amino-acid metabolism, unspecified
0.039 0.960 0.001
E72.8 Other specified disorders of amino-acid metabolism
0.039 0.960 0.001
E72.5 Disorders of glycine metabolism
0.039 0.960 0.001
E72.4 Disorders of ornithine metabolism
0.039 0.960 0.001
E72.3 Disorders of lysine and hydroxylysine metabolism
0.039 0.960 0.001
E72.2 Disorders of urea cycle metabolism
0.039 0.960 0.001
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.039 0.960 0.001
E72.0 Disorders of amino-acid transport
0.039 0.960 0.001
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.039 0.960 0.001
E76.8 Other disorders of glucosaminoglycan metabolism
0.039 0.960 0.001
E76.3 Mucopolysaccharidosis, unspecified
0.039 0.960 0.001
E76.2 Other mucopolysaccharidoses
0.039 0.960 0.001
E76.1 Mucopolysaccharidosis, type II
0.039 0.960 0.001
E76.0 Mucopolysaccharidosis, type I
0.039 0.960 0.001
E77.9 Disorder of glycoprotein metabolism, unspecified
0.039 0.960 0.001
E77.8 Other disorders of glycoprotein metabolism
0.039 0.960 0.001
E77.1 Defects in glycoprotein degradation
0.039 0.960 0.001
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.039 0.960 0.001
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.039 0.960 0.001
E79.8 Other disorders of purine and pyrimidine metabolism
0.039 0.960 0.001
E79.1 Lesch-Nyhan syndrome
0.039 0.960 0.001
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.039 0.960 0.001
E78.4 Other hyperlipidaemia
0.040 0.960 0.000
E78.5 Hyperlipidaemia, unspecified
0.039 0.961 0.000
E88.8 Other specified metabolic disorders
0.039 0.961 0.001
E85.4 Organ-limited amyloidosis
0.038 0.961 0.001
E88.1 Lipodystrophy, not elsewhere classified
0.037 0.962 0.001
E83.4 Disorders of magnesium metabolism
0.018 0.962 0.020
E04.9 Non-toxic goitre, unspecified
0.037 0.963 0.000
R39 Other symptoms and signs involving the urinary system
0.000 0.963 0.037
E74.9 Disorder of carbohydrate metabolism, unspecified
0.036 0.963 0.001
E74.8 Other specified disorders of carbohydrate metabolism
0.036 0.963 0.001
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.036 0.963 0.001
E74.2 Disorders of galactose metabolism
0.036 0.963 0.001
E74.1 Disorders of fructose metabolism
0.036 0.963 0.001
E74.0 Glycogen storage disease
0.036 0.963 0.001
E85.8 Other amyloidosis
0.034 0.965 0.001
E85.2 Heredofamilial amyloidosis, unspecified
0.034 0.965 0.001
E85.1 Neuropathic heredofamilial amyloidosis
0.034 0.965 0.001
E85.0 Nonneuropathic heredofamilial amyloidosis
0.034 0.965 0.001
K93 Disorders of other digestive organs in diseases classified elsewhere
0.035 0.965 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.035 0.965 0.000
E85.3 Secondary systemic amyloidosis
0.032 0.967 0.001
E11.9 Without complications
0.033 0.967 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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