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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs204896
log Bayes Factor = 18.0696
Chromosome 6   position 32,064,098  (GRCh37) Explore rs204896 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.005 0.995
E10.3 With ophthalmic complications
0.000 0.005 0.995
E65-E68 Obesity and other hyperalimentation
0.000 0.008 0.992
E11.3 With ophthalmic complications
0.000 0.010 0.990
E10.1 With ketoacidosis
0.000 0.010 0.990
E66 Obesity
0.000 0.014 0.986
E14 Unspecified diabetes mellitus
0.000 0.017 0.983
E66.8 Other obesity
0.000 0.026 0.974
E14.9 Without complications
0.000 0.038 0.962
E11.9 Without complications
0.000 0.069 0.931
E66.9 Obesity, unspecified
0.000 0.077 0.923
M06 Other rheumatoid arthritis
0.000 0.078 0.922
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.080 0.920
E11.5 With peripheral circulatory complications
0.000 0.097 0.903
E10.5 With peripheral circulatory complications
0.000 0.116 0.884
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.123 0.877
E11.4 With neurological complications
0.000 0.150 0.850
E10.4 With neurological complications
0.000 0.150 0.850
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.160 0.840
M05-M14 Inflammatory polyarthropathies
0.000 0.163 0.837
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.171 0.829
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.172 0.828
M05 Seropositive rheumatoid arthritis
0.000 0.186 0.814
E14.3 With ophthalmic complications
0.000 0.188 0.812
E10.2 With renal complications
0.000 0.190 0.810
E05.9 Thyrotoxicosis, unspecified
0.000 0.200 0.800
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.202 0.798
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.223 0.777
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.226 0.774
E11.2 With renal complications
0.000 0.227 0.773
E06 Thyroiditis
0.000 0.241 0.759
M06.0 Seronegative rheumatoid arthritis
0.000 0.250 0.750
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.251 0.749
M06.3 Rheumatoid nodule
0.000 0.254 0.746
E65 Localised adiposity
0.000 0.274 0.726
E50-E64 Other nutritional deficiencies
0.000 0.282 0.718
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.716
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.716
E11.7 With multiple complications
0.000 0.284 0.716
E67 Other hyperalimentation
0.000 0.289 0.711
E68 Sequelae of hyperalimentation
0.000 0.289 0.711
M13 Other arthritis
0.000 0.292 0.708
E66.1 Drug-induced obesity
0.000 0.293 0.707
E66.0 Obesity due to excess calories
0.000 0.293 0.707
E11.1 With ketoacidosis
0.000 0.293 0.707
E14.8 With unspecified complications
0.000 0.295 0.704
E14.7 With multiple complications
0.000 0.295 0.704
E14.6 With other specified complications
0.000 0.295 0.704
E14.5 With peripheral circulatory complications
0.000 0.295 0.704
E14.4 With neurological complications
0.000 0.295 0.704
E14.2 Withrenal complications
0.000 0.295 0.704
E14.1 With ketoacidosis
0.000 0.295 0.704
E14.0 With coma
0.000 0.295 0.704
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.310 0.690
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.315 0.685
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.317 0.683
E11.8 With unspecified complications
0.000 0.326 0.673
M10 Gout
0.000 0.338 0.662
M06.8 Other specified rheumatoid arthritis
0.000 0.339 0.661
M06.2 Rheumatoid bursitis
0.000 0.339 0.661
M06.1 Adult-onset Still's disease
0.000 0.339 0.661
E05.8 Other thyrotoxicosis
0.000 0.340 0.659
E05.5 Thyroid crisis or storm
0.000 0.340 0.659
E05.4 Thyrotoxicosis factitia
0.000 0.340 0.659
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.340 0.659
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.340 0.659
E40-E46 Malnutrition
0.000 0.350 0.650
E11.6 With other specified complications
0.000 0.358 0.642
M14 Arthropathies in other diseases classified elsewhere
0.000 0.360 0.640
E11.0 With coma
0.000 0.378 0.622
M06.34 Rheumatoid nodule (Hand)
0.000 0.380 0.619
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.387 0.613
E06.3 Autoimmune thyroiditis
0.000 0.390 0.610
M12 Other specific arthropathies
0.000 0.400 0.600
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.400 0.600
M08 Juvenile arthritis
0.000 0.400 0.600
M13.0 Polyarthritis, unspecified
0.000 0.408 0.592
E07 Other disorders of thyroid
0.000 0.411 0.589
M05.8 Other seropositive rheumatoid arthritis
0.000 0.416 0.584
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.416 0.584
M05.2 Rheumatoid vasculitis
0.000 0.416 0.584
M05.1 Rheumatoid lung disease
0.000 0.416 0.584
M05.0 Felty's syndrome
0.000 0.416 0.584
E61 Deficiency of other nutrient elements
0.000 0.419 0.581
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.422 0.578
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.427 0.572
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.427 0.572
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.427 0.572
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.427 0.572
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.427 0.572
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.427 0.572
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.427 0.572
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.427 0.572
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.432 0.568
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.440 0.560
E13 Other specified diabetes mellitus
0.000 0.445 0.554
E03.8 Other specified hypothyroidism
0.000 0.448 0.552
M13.9 Arthritis, unspecified
0.000 0.454 0.546
E06.5 Other chronic thyroiditis
0.000 0.456 0.544
E06.4 Drug-induced thyroiditis
0.000 0.456 0.544
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.456 0.544
E06.1 Subacute thyroiditis
0.000 0.456 0.544
E06.0 Acute thyroiditis
0.000 0.456 0.544
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.462 0.538
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.462 0.538
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.462 0.538
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.462 0.538
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.462 0.538
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.462 0.538
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.462 0.538
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.462 0.538
M10.9 Gout, unspecified
0.000 0.463 0.537
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.465 0.535
M06.38 Rheumatoid nodule (Other)
0.000 0.465 0.535
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.465 0.535
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.465 0.535
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.465 0.535
M06.33 Rheumatoid nodule (Forearm)
0.000 0.465 0.535
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.465 0.535
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.465 0.535
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.465 0.535
M06.4 Inflammatory polyarthropathy
0.001 0.466 0.533
M13.00 Polyarthritis, unspecified (Multiple sites)
0.000 0.482 0.518
E53 Deficiency of other B group vitamins
0.000 0.484 0.516
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.485 0.514
E63 Other nutritional deficiencies
0.000 0.485 0.514
E56 Other vitamin deficiencies
0.000 0.485 0.514
E51 Thiamine deficiency
0.000 0.485 0.514
E50 Vitamin A deficiency
0.000 0.485 0.514
E60 Dietary zinc deficiency
0.000 0.485 0.514
E59 Dietary selenium deficiency
0.000 0.485 0.514
E58 Dietary calcium deficiency
0.000 0.485 0.514
E54 Ascorbic acid deficiency
0.000 0.485 0.514
E52 Niacin deficiency [pellagra]
0.000 0.485 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E06.9 Thyroiditis, unspecified
0.000 0.488 0.512
E20-E35 Disorders of other endocrine glands
0.000 0.489 0.510
E67.8 Other specified hyperalimentation
0.000 0.490 0.510
E67.3 Hypervitaminosis D
0.000 0.490 0.510
E67.2 Megavitamin-B6 syndrome
0.000 0.490 0.510
E67.1 Hypercarotenaemia
0.000 0.490 0.510
E67.0 Hypervitaminosis A
0.000 0.490 0.510
M13.8 Other specified arthritis
0.000 0.492 0.507
M13.1 Monoarthritis, not elsewhere classified
0.000 0.492 0.507
M13.94 Arthritis, unspecified (Hand)
0.000 0.495 0.505
M13.99 Arthritis, unspecified (Site unspecified)
0.000 0.499 0.501
M14.6 Neuropathic arthropathy
0.000 0.501 0.499
M11 Other crystal arthropathies
0.001 0.504 0.495
M10.97 Gout, unspecified (Ankle and foot)
0.000 0.506 0.494
E15 Nondiabetic hypoglycaemic coma
0.000 0.509 0.491
E61.1 Iron deficiency
0.000 0.516 0.484
M10.4 Other secondary gout
0.000 0.525 0.475
M10.3 Gout due to impairment of renal function
0.000 0.525 0.475
M10.2 Drug-induced gout
0.000 0.525 0.475
M10.1 Lead-induced gout
0.000 0.525 0.475
M10.0 Idiopathic gout
0.000 0.525 0.475
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.526 0.474
M06.18 Adult-onset Still's disease (Other)
0.000 0.526 0.474
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.526 0.474
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.526 0.474
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.526 0.474
M06.14 Adult-onset Still's disease (Hand)
0.000 0.526 0.474
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.526 0.474
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.526 0.474
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.526 0.474
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.526 0.474
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.526 0.474
M06.28 Rheumatoid bursitis (Other)
0.000 0.526 0.474
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.526 0.474
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.526 0.474
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.526 0.474
M06.24 Rheumatoid bursitis (Hand)
0.000 0.526 0.474
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.526 0.474
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.526 0.474
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.526 0.474
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.526 0.474
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.526 0.474
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.526 0.474
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.526 0.474
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.526 0.474
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.526 0.474
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.526 0.474
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.526 0.474
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.526 0.474
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.526 0.474
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.526 0.474
M07 Psoriatic and enteropathic arthropathies
0.000 0.531 0.469
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.534 0.466
E45 Retarded development following protein-energy malnutrition
0.000 0.534 0.466
E43 Unspecified severe protein-energy malnutrition
0.000 0.534 0.466
E42 Marasmic kwashiorkor
0.000 0.534 0.466
E41 Nutritional marasmus
0.000 0.534 0.466
E40 Kwashiorkor
0.000 0.534 0.466
E16 Other disorders of pancreatic internal secretion
0.000 0.540 0.460
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.541 0.459
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.541 0.459
M14.4 Arthropathy in amyloidosis
0.000 0.541 0.459
M14.3 Lipoid dermatoarthritis
0.000 0.541 0.459
M14.2 Diabetic arthropathy
0.000 0.541 0.459
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.541 0.459
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.541 0.459
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.000 0.550 0.450
M13.93 Arthritis, unspecified (Forearm)
0.000 0.565 0.435
M08.9 Juvenile arthritis, unspecified
0.000 0.569 0.430
M08.8 Other juvenile arthritis
0.000 0.569 0.430
M08.4 Pauciarticular juvenile arthritis
0.000 0.569 0.430
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.569 0.430
M08.2 Juvenile arthritis with systemic onset
0.000 0.569 0.430
M08.1 Juvenile ankylosing spondylitis
0.000 0.569 0.430
M08.0 Juvenile rheumatoid arthritis
0.000 0.569 0.430
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.569 0.430
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.569 0.430
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.569 0.430
M09.0 Juvenile arthritis in psoriasis
0.000 0.569 0.430
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.569 0.430
M12.5 Traumatic arthropathy
0.000 0.569 0.430
M12.4 Intermittent hydrarthrosis
0.000 0.569 0.430
M12.3 Palindromic rheumatism
0.000 0.569 0.430
M12.2 Villonodular synovitis (pigmented)
0.000 0.569 0.430
M12.1 Kaschin-Beck disease
0.000 0.569 0.430
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.569 0.430
M13.08 Polyarthritis, unspecified (Other)
0.000 0.575 0.425
M13.07 Polyarthritis, unspecified (Ankle and foot)
0.000 0.575 0.425
M13.06 Polyarthritis, unspecified (Lower leg)
0.000 0.575 0.425
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)
0.000 0.575 0.425
M13.04 Polyarthritis, unspecified (Hand)
0.000 0.575 0.425
M13.03 Polyarthritis, unspecified (Forearm)
0.000 0.575 0.425
M13.02 Polyarthritis, unspecified (Upper arm)
0.000 0.575 0.425
M13.01 Polyarthritis, unspecified (Shoulder region)
0.000 0.575 0.425
E07.1 Dyshormogenetic goitre
0.000 0.577 0.422
E07.0 Hypersecretion of calcitonin
0.000 0.577 0.422
M05.09 Felty's syndrome (Site unspecified)
0.000 0.581 0.419
M05.08 Felty's syndrome (Other)
0.000 0.581 0.419
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.581 0.419
M05.06 Felty's syndrome (Lower leg)
0.000 0.581 0.419
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.581 0.419
M05.04 Felty's syndrome (Hand)
0.000 0.581 0.419
M05.03 Felty's syndrome (Forearm)
0.000 0.581 0.419
M05.02 Felty's syndrome (Upper arm)
0.000 0.581 0.419
M05.01 Felty's syndrome (Shoulder region)
0.000 0.581 0.419
M05.00 Felty's syndrome (Multiple sites)
0.000 0.581 0.419
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.581 0.419
M05.18 Rheumatoid lung disease (Other)
0.000 0.581 0.419
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.581 0.419
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.581 0.419
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.581 0.419
M05.14 Rheumatoid lung disease (Hand)
0.000 0.581 0.419
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.581 0.419
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.581 0.419
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.581 0.419
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.581 0.419
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.581 0.419
M05.28 Rheumatoid vasculitis (Other)
0.000 0.581 0.419
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.581 0.419
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.581 0.419
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.581 0.419
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.581 0.419
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.581 0.419
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.581 0.419
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.581 0.419
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.581 0.419
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.581 0.419
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.581 0.419
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.581 0.419
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.581 0.419
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.581 0.419
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.581 0.419
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.581 0.419
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.581 0.419
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.581 0.419
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.581 0.419
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.581 0.419
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.581 0.419
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.581 0.419
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.581 0.419
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.581 0.419
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.581 0.419
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.581 0.419
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.581 0.419
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.581 0.419
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.581 0.419
E61.9 Deficiency of nutrient element, unspecified
0.000 0.583 0.417
E61.8 Deficiency of other specified nutrient elements
0.000 0.583 0.417
E61.7 Deficiency of multiple nutrient elements
0.000 0.583 0.417
E61.6 Vanadium deficiency
0.000 0.583 0.417
E61.5 Molybdenum deficiency
0.000 0.583 0.417
E61.4 Chromium deficiency
0.000 0.583 0.417
E61.3 Manganese deficiency
0.000 0.583 0.417
E61.2 Magnesium deficiency
0.000 0.583 0.417
E61.0 Copper deficiency
0.000 0.583 0.417
E53.8 Deficiency of other specified B group vitamins
0.000 0.583 0.417
E55 Vitamin D deficiency
0.000 0.586 0.414
M10.96 Gout, unspecified (Lower leg)
0.000 0.587 0.413
E27 Other disorders of adrenal gland
0.000 0.589 0.411
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.001 0.590 0.410
E07.8 Other specified disorders of thyroid
0.000 0.590 0.410
M13.09 Polyarthritis, unspecified (Site unspecified)
0.000 0.592 0.408
M13.91 Arthritis, unspecified (Shoulder region)
0.000 0.593 0.407
E46 Unspecified protein-energy malnutrition
0.000 0.601 0.399
E13.8 With unspecified complications
0.000 0.602 0.397
E13.7 With multiple complications
0.000 0.602 0.397
E13.6 With other specified complications
0.000 0.602 0.397
E13.5 With peripheral circulatory complications
0.000 0.602 0.397
E13.4 With neurological complications
0.000 0.602 0.397
E13.3 With ophthalmic complications
0.000 0.602 0.397
E13.2 With renal complications
0.000 0.602 0.397
E13.1 With ketoacidosis
0.000 0.602 0.397
E13.0 With coma
0.000 0.602 0.397
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.604 0.396
M13.92 Arthritis, unspecified (Upper arm)
0.000 0.608 0.392
M10.98 Gout, unspecified (Other)
0.000 0.615 0.385
M10.95 Gout, unspecified (Pelvic region and thigh)
0.000 0.615 0.385
M10.93 Gout, unspecified (Forearm)
0.000 0.615 0.385
M10.92 Gout, unspecified (Upper arm)
0.000 0.615 0.385
M10.91 Gout, unspecified (Shoulder region)
0.000 0.615 0.385
M10.90 Gout, unspecified (Multiple sites)
0.000 0.615 0.385
M06.48 Inflammatory polyarthropathy (Other)
0.001 0.617 0.382
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.001 0.617 0.382
M06.46 Inflammatory polyarthropathy (Lower leg)
0.001 0.617 0.382
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.001 0.617 0.382
M06.44 Inflammatory polyarthropathy (Hand)
0.001 0.617 0.382
M06.43 Inflammatory polyarthropathy (Forearm)
0.001 0.617 0.382
M06.42 Inflammatory polyarthropathy (Upper arm)
0.001 0.617 0.382
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.001 0.617 0.382
M10.94 Gout, unspecified (Hand)
0.000 0.620 0.380
E27.1 Primary adrenocortical insufficiency
0.000 0.621 0.379
E23 Hypofunction and other disorders of pituitary gland
0.000 0.626 0.374
E28 Ovarian dysfunction
0.000 0.630 0.370
E53.1 Pyridoxine deficiency
0.000 0.630 0.370
E53.0 Riboflavin deficiency
0.000 0.630 0.370
E50.9 Vitamin A deficiency, unspecified
0.000 0.631 0.369
E50.8 Other manifestations of vitamin A deficiency
0.000 0.631 0.369
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.631 0.369
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.631 0.369
E50.5 Vitamin A deficiency with night blindness
0.000 0.631 0.369
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.631 0.369
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.631 0.369
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.631 0.369
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.631 0.369
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.631 0.369
E51.9 Thiamine deficiency, unspecified
0.000 0.631 0.369
E51.8 Other manifestations of thiamine deficiency
0.000 0.631 0.369
E51.2 Wernicke's encephalopathy
0.000 0.631 0.369
E51.1 Beriberi
0.000 0.631 0.369
E56.9 Vitamin deficiency, unspecified
0.000 0.631 0.369
E56.8 Deficiency of other vitamins
0.000 0.631 0.369
E56.1 Deficiency of vitamin K
0.000 0.631 0.369
E56.0 Deficiency of vitamin E
0.000 0.631 0.369
E63.9 Nutritional deficiency, unspecified
0.000 0.631 0.369
E63.8 Other specified nutritional deficiencies
0.000 0.631 0.369
E63.1 Imbalance of constituents of food intake
0.000 0.631 0.369
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.631 0.369
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.631 0.369
E64.8 Sequelae of other nutritional deficiencies
0.000 0.631 0.369
E64.3 Sequelae of rickets
0.000 0.631 0.369
E64.2 Sequelae of vitamin C deficiency
0.000 0.631 0.369
E64.1 Sequelae of vitamin A deficiency
0.000 0.631 0.369
E64.0 Sequelae of protein-energy malnutrition
0.000 0.631 0.369
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.634 0.366
E32 Diseases of thymus
0.000 0.634 0.366
E31 Polyglandular dysfunction
0.000 0.634 0.366
E30 Disorders of puberty, not elsewhere classified
0.000 0.634 0.366
E25 Adrenogenital disorders
0.000 0.634 0.366
E20 Hypoparathyroidism
0.000 0.634 0.366
M13.19 Monoarthritis, not elsewhere classified (Site unspecified)
0.000 0.636 0.364
M13.18 Monoarthritis, not elsewhere classified (Other)
0.000 0.636 0.364
M13.17 Monoarthritis, not elsewhere classified (Ankle and foot)
0.000 0.636 0.364
M13.16 Monoarthritis, not elsewhere classified (Lower leg)
0.000 0.636 0.364
M13.15 Monoarthritis, not elsewhere classified (Pelvic region and thigh)
0.000 0.636 0.364
M13.14 Monoarthritis, not elsewhere classified (Hand)
0.000 0.636 0.364
M13.13 Monoarthritis, not elsewhere classified (Forearm)
0.000 0.636 0.364
M13.12 Monoarthritis, not elsewhere classified (Upper arm)
0.000 0.636 0.364
M13.11 Monoarthritis, not elsewhere classified (Shoulder region)
0.000 0.636 0.364
M13.10 Monoarthritis, not elsewhere classified (Multiple sites)
0.000 0.636 0.364
M13.89 Other specified arthritis (Site unspecified)
0.000 0.636 0.364
M13.88 Other specified arthritis (Other)
0.000 0.636 0.364
M13.87 Other specified arthritis (Ankle and foot)
0.000 0.636 0.364
M13.86 Other specified arthritis (Lower leg)
0.000 0.636 0.364
M13.85 Other specified arthritis (Pelvic region and thigh)
0.000 0.636 0.364
M13.84 Other specified arthritis (Hand)
0.000 0.636 0.364
M13.83 Other specified arthritis (Forearm)
0.000 0.636 0.364
M13.82 Other specified arthritis (Upper arm)
0.000 0.636 0.364
M13.81 Other specified arthritis (Shoulder region)
0.000 0.636 0.364
M13.80 Other specified arthritis (Multiple sites)
0.000 0.636 0.364
E34 Other endocrine disorders
0.000 0.644 0.356
M11.9 Crystal arthropathy, unspecified
0.001 0.645 0.355
M11.8 Other specified crystal arthropathies
0.001 0.645 0.355
M11.1 Familial chondrocalcinosis
0.001 0.645 0.355
M11.0 Hydroxyapatite deposition disease
0.001 0.645 0.355
E29 Testicular dysfunction
0.000 0.645 0.355
M13.98 Arthritis, unspecified (Other)
0.000 0.652 0.347
M10.09 Idiopathic gout (Site unspecified)
0.000 0.659 0.340
M10.08 Idiopathic gout (Other)
0.000 0.659 0.340
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.659 0.340
M10.06 Idiopathic gout (Lower leg)
0.000 0.659 0.340
M10.05 Idiopathic gout (Pelvic region and thigh)
0.000 0.659 0.340
M10.04 Idiopathic gout (Hand)
0.000 0.659 0.340
M10.03 Idiopathic gout (Forearm)
0.000 0.659 0.340
M10.02 Idiopathic gout (Upper arm)
0.000 0.659 0.340
M10.01 Idiopathic gout (Shoulder region)
0.000 0.659 0.340
M10.00 Idiopathic gout (Multiple sites)
0.000 0.659 0.340
M10.19 Lead-induced gout (Site unspecified)
0.000 0.659 0.340
M10.18 Lead-induced gout (Other)
0.000 0.659 0.340
M10.17 Lead-induced gout (Ankle and foot)
0.000 0.659 0.340
M10.16 Lead-induced gout (Lower leg)
0.000 0.659 0.340
M10.15 Lead-induced gout (Pelvic region and thigh)
0.000 0.659 0.340
M10.14 Lead-induced gout (Hand)
0.000 0.659 0.340
M10.13 Lead-induced gout (Forearm)
0.000 0.659 0.340
M10.12 Lead-induced gout (Upper arm)
0.000 0.659 0.340
M10.11 Lead-induced gout (Shoulder region)
0.000 0.659 0.340
M10.10 Lead-induced gout (Multiple sites)
0.000 0.659 0.340
M10.29 Drug-induced gout (Site unspecified)
0.000 0.659 0.340
M10.28 Drug-induced gout (Other)
0.000 0.659 0.340
M10.27 Drug-induced gout (Ankle and foot)
0.000 0.659 0.340
M10.26 Drug-induced gout (Lower leg)
0.000 0.659 0.340
M10.25 Drug-induced gout (Pelvic region and thigh)
0.000 0.659 0.340
M10.24 Drug-induced gout (Hand)
0.000 0.659 0.340
M10.23 Drug-induced gout (Forearm)
0.000 0.659 0.340
M10.22 Drug-induced gout (Upper arm)
0.000 0.659 0.340
M10.21 Drug-induced gout (Shoulder region)
0.000 0.659 0.340
M10.20 Drug-induced gout (Multiple sites)
0.000 0.659 0.340
M10.39 Gout due to impairment of renal function (Site unspecified)
0.000 0.659 0.340
M10.38 Gout due to impairment of renal function (Other)
0.000 0.659 0.340
M10.37 Gout due to impairment of renal function (Ankle and foot)
0.000 0.659 0.340
M10.36 Gout due to impairment of renal function (Lower leg)
0.000 0.659 0.340
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)
0.000 0.659 0.340
M10.34 Gout due to impairment of renal function (Hand)
0.000 0.659 0.340
M10.33 Gout due to impairment of renal function (Forearm)
0.000 0.659 0.340
M10.32 Gout due to impairment of renal function (Upper arm)
0.000 0.659 0.340
M10.31 Gout due to impairment of renal function (Shoulder region)
0.000 0.659 0.340
M10.30 Gout due to impairment of renal function (Multiple sites)
0.000 0.659 0.340
M10.49 Other secondary gout (Site unspecified)
0.000 0.659 0.340
M10.48 Other secondary gout (Other)
0.000 0.659 0.340
M10.47 Other secondary gout (Ankle and foot)
0.000 0.659 0.340
M10.46 Other secondary gout (Lower leg)
0.000 0.659 0.340
M10.45 Other secondary gout (Pelvic region and thigh)
0.000 0.659 0.340
M10.44 Other secondary gout (Hand)
0.000 0.659 0.340
M10.43 Other secondary gout (Forearm)
0.000 0.659 0.340
M10.42 Other secondary gout (Upper arm)
0.000 0.659 0.340
M10.41 Other secondary gout (Shoulder region)
0.000 0.659 0.340
M10.40 Other secondary gout (Multiple sites)
0.000 0.659 0.340
M07.6 Other enteropathic arthropathies
0.000 0.663 0.336
M07.5 Arthropathy in ulcerative colitis
0.000 0.663 0.336
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.663 0.336
M07.2 Psoriatic spondylitis
0.000 0.663 0.336
M07.1 Arthritis mutilans
0.000 0.663 0.336
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.663 0.336
E44.1 Mild protein-energy malnutrition
0.000 0.666 0.334
E44.0 Moderate protein-energy malnutrition
0.000 0.666 0.334
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.670 0.330
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.670 0.330
E16.4 Abnormal secretion of gastrin
0.000 0.670 0.330
E16.3 Increased secretion of glucagon
0.000 0.670 0.330
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.670 0.330
E26 Hyperaldosteronism
0.000 0.672 0.328
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.675 0.325
E16.1 Other hypoglycaemia
0.000 0.681 0.318
E07.9 Disorder of thyroid, unspecified
0.000 0.685 0.315
E24 Cushing's syndrome
0.000 0.688 0.312
E16.2 Hypoglycaemia, unspecified
0.000 0.689 0.311

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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