TreeWAS – Variant ID: rs204989

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	1.000	0.000	0.000
K90 Intestinal malabsorption	0.999	0.001	0.000
R31 Unspecified haematuria	0.000	0.001	0.999
Chapter IX Diseases of the circulatory system	0.999	0.001	0.000
N00-N08 Glomerular diseases	0.999	0.001	0.000
E11 Non-insulin-dependent diabetes mellitus	0.999	0.001	0.000
D64.9 Anaemia, unspecified	0.998	0.002	0.000
E14.9 Without complications	0.998	0.002	0.000
D64 Other anaemias	0.998	0.002	0.000
D60-D64 Aplastic and other anaemias	0.998	0.002	0.000
N04 Nephrotic syndrome	0.997	0.003	0.000
I73 Other peripheral vascular diseases	0.996	0.004	0.000
E14.3 With ophthalmic complications	0.995	0.005	0.000
N04.9 Unspecified	0.994	0.006	0.000
K90.9 Intestinal malabsorption, unspecified	0.993	0.007	0.000
D50-D53 Nutritional anaemias	0.992	0.008	0.000
Chapter XIV Diseases of the genitourinary system	0.992	0.008	0.000
N05 Unspecified nephritic syndrome	0.988	0.012	0.000
D51 Vitamin B12 deficiency anaemia	0.986	0.014	0.000
I74 Arterial embolism and thrombosis	0.985	0.015	0.000
I77 Other disorders of arteries and arterioles	0.985	0.015	0.000
E10.4 With neurological complications	0.984	0.016	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.982	0.018	0.000
N17-N19 Renal failure	0.981	0.019	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.980	0.020	0.000
E10.2 With renal complications	0.980	0.020	0.000
I73.9 Peripheral vascular disease, unspecified	0.980	0.020	0.000
N18 Chronic renal failure	0.979	0.021	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.979	0.021	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.978	0.022	0.000
J45.9 Asthma, unspecified	0.975	0.025	0.000
E11.9 Without complications	0.974	0.026	0.000
I77.1 Stricture of artery	0.973	0.027	0.000
J45 Asthma	0.970	0.030	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.966	0.034	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.966	0.034	0.000
J40-J47 Chronic lower respiratory diseases	0.966	0.034	0.000
I73.0 Raynaud's syndrome	0.963	0.037	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.961	0.039	0.000
Chapter VI Diseases of the nervous system	0.960	0.040	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.958	0.042	0.000
D80-D89 Certain disorders involving the immune mechanism	0.955	0.045	0.000
M35.0 Sicca syndrome [Sjogren]	0.952	0.048	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.949	0.051	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.947	0.053	0.000
E50-E64 Other nutritional deficiencies	0.945	0.055	0.000
M15-M19 Arthrosis	0.944	0.056	0.000
N05.2 Diffuse membranous glomerulonephritis	0.942	0.058	0.000
K90-K93 Other diseases of the digestive system	0.940	0.060	0.000
J44 Other chronic obstructive pulmonary disease	0.940	0.060	0.000
Chapter XI Diseases of the digestive system	0.936	0.064	0.000
G51 Facial nerve disorders	0.936	0.064	0.000
N18.9 Chronic renal failure, unspecified	0.934	0.066	0.000
M18 Arthrosis of first carpometacarpal joint	0.932	0.068	0.000
K70-K77 Diseases of liver	0.930	0.070	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.929	0.071	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.928	0.072	0.000
K75 Other inflammatory liver diseases	0.928	0.072	0.000
E20-E35 Disorders of other endocrine glands	0.927	0.073	0.000
E11.3 With ophthalmic complications	0.926	0.074	0.000
M35 Other systemic involvement of connective tissue	0.924	0.076	0.000
E70-E90 Metabolic disorders	0.924	0.076	0.000
J46 Status asthmaticus	0.923	0.077	0.000
Chapter X Diseases of the respiratory system	0.922	0.078	0.000
M20-M25 Other joint disorders	0.922	0.078	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.919	0.081	0.000
E89.0 Postprocedural hypothyroidism	0.919	0.081	0.000
E11.5 With peripheral circulatory complications	0.916	0.084	0.000
M05-M14 Inflammatory polyarthropathies	0.133	0.087	0.779
K75.4 Autoimmune hepatitis	0.911	0.089	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.906	0.094	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.906	0.094	0.000
H36.0 Diabetic retinopathy	0.905	0.095	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.097	0.903
E27.1 Primary adrenocortical insufficiency	0.902	0.098	0.000
E27 Other disorders of adrenal gland	0.901	0.099	0.000
M06 Other rheumatoid arthritis	0.003	0.099	0.897
M06.9 Rheumatoid arthritis, unspecified	0.000	0.100	0.900
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.899	0.101	0.000
M70-M79 Other soft tissue disorders	0.896	0.104	0.000
G51.0 Bell's palsy	0.892	0.108	0.000
H36 Retinal disorders in diseases classified elsewhere	0.890	0.110	0.000
K73 Chronic hepatitis, not elsewhere classified	0.889	0.111	0.000
N18.2 Chronic kidney disease, stage 2	0.887	0.113	0.000
M15 Polyarthrosis	0.885	0.115	0.000
Q50-Q56 Congenital malformations of genital organs	0.885	0.115	0.000
E11.1 With ketoacidosis	0.884	0.116	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.884	0.116	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.883	0.117	0.000
N18.0 End-stage renal disease	0.883	0.117	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.882	0.118	0.000
J43 Emphysema	0.882	0.118	0.000
D80 Immunodeficiency with predominantly antibody defects	0.881	0.119	0.000
Chapter VII Diseases of the eye and adnexa	0.881	0.119	0.000
H30-H36 Disorders of choroid and retina	0.878	0.122	0.000
M72 Fibroblastic disorders	0.877	0.123	0.000
I60-I69 Cerebrovascular diseases	0.874	0.125	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.871	0.129	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.870	0.130	0.000
G51.9 Disorder of facial nerve, unspecified	0.868	0.132	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.866	0.134	0.000
M06.3 Rheumatoid nodule	0.001	0.136	0.863
G59.0 Diabetic mononeuropathy	0.863	0.137	0.000
K75.8 Other specified inflammatory liver diseases	0.863	0.137	0.000
E53 Deficiency of other B group vitamins	0.862	0.138	0.000
N18.4 Chronic kidney disease, stage 4	0.862	0.138	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.861	0.139	0.000
N25-N29 Other disorders of kidney and ureter	0.860	0.140	0.000
E14.8 With unspecified complications	0.857	0.143	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.856	0.143	0.000
I65.2 Occlusion and stenosis of carotid artery	0.856	0.144	0.000
N05.1 Focal and segmental glomerular lesions	0.854	0.146	0.000
I63 Cerebral infarction	0.851	0.149	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.846	0.154	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.845	0.155	0.000
M05 Seropositive rheumatoid arthritis	0.064	0.156	0.780
E14.1 With ketoacidosis	0.843	0.157	0.000
E10.8 With unspecified complications	0.840	0.159	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.840	0.160	0.000
E06 Thyroiditis	0.839	0.161	0.000
E03.8 Other specified hypothyroidism	0.836	0.164	0.000
E14.2 Withrenal complications	0.830	0.170	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.829	0.171	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.827	0.173	0.000
E53.8 Deficiency of other specified B group vitamins	0.822	0.178	0.000
N04.2 Diffuse membranous glomerulonephritis	0.821	0.179	0.000
E11.4 With neurological complications	0.816	0.184	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.816	0.184	0.000
M60-M63 Disorders of muscles	0.815	0.185	0.000
E07 Other disorders of thyroid	0.810	0.190	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.191	0.809
M32 Systemic lupus erythematosus	0.806	0.194	0.000
M86-M90 Other osteopathies	0.806	0.194	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.806	0.194	0.000
Q60-Q64 Congenital malformations of the urinary system	0.803	0.197	0.000
E10.0 With coma	0.802	0.198	0.000
N18.8 Other chronic renal failure	0.800	0.200	0.000
E16.1 Other hypoglycaemia	0.797	0.203	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.013	0.204	0.784
H25-H28 Disorders of lens	0.795	0.205	0.000
N05.9 Unspecified	0.795	0.205	0.000
N04.1 Focal and segmental glomerular lesions	0.793	0.207	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.793	0.207	0.000
G50 Disorders of trigeminal nerve	0.792	0.208	0.000
D83 Common variable immunodeficiency	0.789	0.211	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.788	0.212	0.000
Q43 Other congenital malformations of intestine	0.788	0.212	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.214	0.785
D51.3 Other dietary vitamin B12 deficiency anaemia	0.785	0.215	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.001	0.216	0.783
D50 Iron deficiency anaemia	0.784	0.216	0.000
N00 Acute nephritic syndrome	0.781	0.219	0.000
M80-M85 Disorders of bone density and structure	0.780	0.220	0.000
K90.8 Other intestinal malabsorption	0.779	0.221	0.000
D53 Other nutritional anaemias	0.778	0.222	0.000
J43.9 Emphysema, unspecified	0.778	0.222	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.778	0.222	0.000
I27 Other pulmonary heart diseases	0.777	0.223	0.000
M06.0 Seronegative rheumatoid arthritis	0.001	0.224	0.774
E14.4 With neurological complications	0.775	0.225	0.000
Q39 Congenital malformations of oesophagus	0.775	0.225	0.000
Q44.6 Cystic disease of liver	0.774	0.226	0.000
I05-I09 Chronic rheumatic heart diseases	0.774	0.226	0.000
E03.1 Congenital hypothyroidism without goitre	0.772	0.228	0.000
M79.8 Other specified soft tissue disorders	0.770	0.230	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.767	0.233	0.000
M00-M03 Infectious arthropathies	0.765	0.234	0.000
K73.9 Chronic hepatitis, unspecified	0.765	0.235	0.000
E55 Vitamin D deficiency	0.765	0.235	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.764	0.236	0.000
Q54 Hypospadias	0.763	0.237	0.000
E10.7 With multiple complications	0.763	0.237	0.000
J90-J94 Other diseases of pleura	0.762	0.238	0.000
I74.8 Embolism and thrombosis of other arteries	0.760	0.240	0.000
N18.5 Chronic kidney disease, stage 5	0.759	0.241	0.000
M15.1 Heberden's nodes (with arthropathy)	0.759	0.241	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.758	0.242	0.000
I27.9 Pulmonary heart disease, unspecified	0.758	0.242	0.000
J92 Pleural plaque	0.756	0.244	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.244	0.756
I77.6 Arteritis, unspecified	0.754	0.246	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.753	0.247	0.000
J45.1 Nonallergic asthma	0.753	0.247	0.000
Chapter I Certain infectious and parasitic diseases	0.752	0.248	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.752	0.248	0.000
N04.0 Minor glomerular abnormality	0.751	0.249	0.000
N18.1 Chronic kidney disease, stage 1	0.749	0.251	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.749	0.251	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.749	0.251	0.000
E78.6 Lipoprotein deficiency	0.747	0.253	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.746	0.254	0.000
E51 Thiamine deficiency	0.744	0.256	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.743	0.257	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.743	0.257	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.742	0.258	0.000
D64.8 Other specified anaemias	0.741	0.259	0.000
I63.8 Other cerebral infarction	0.741	0.259	0.000
E78.2 Mixed hyperlipidaemia	0.740	0.260	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.001	0.261	0.738
I73.1 Thromboangiitis obliterans [Buerger]	0.738	0.262	0.000
G70-G73 Diseases of myoneural junction and muscle	0.737	0.263	0.000
N25 Disorders resulting from impaired renal tubular function	0.736	0.264	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.736	0.264	0.000
M15.4 Erosive (osteo)arthrosis	0.736	0.264	0.000
G30-G32 Other degenerative diseases of the nervous system	0.735	0.265	0.000
K75.0 Abscess of liver	0.735	0.265	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.735	0.265	0.000
M15.8 Other polyarthrosis	0.734	0.266	0.000
H27 Other disorders of lens	0.734	0.266	0.000
J92.0 Pleural plaque with presence of asbestos	0.734	0.266	0.000
E70 Disorders of aromatic amino-acid metabolism	0.734	0.266	0.000
E11.8 With unspecified complications	0.733	0.267	0.000
E78.5 Hyperlipidaemia, unspecified	0.733	0.267	0.000
M24 Other specific joint derangements	0.733	0.267	0.000
Q44.5 Other congenital malformations of bile ducts	0.731	0.268	0.000
D50.9 Iron deficiency anaemia, unspecified	0.731	0.269	0.000
Q00-Q07 Congenital malformations of the nervous system	0.730	0.270	0.000
M06.4 Inflammatory polyarthropathy	0.002	0.272	0.726
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.727	0.273	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.724	0.276	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.723	0.276	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.721	0.279	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.718	0.282	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.718	0.282	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
K90.3 Pancreatic steatorrhoea	0.716	0.283	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.716	0.283	0.000
K90.1 Tropical sprue	0.716	0.283	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.716	0.284	0.000
N06 Isolated proteinuria with specified morphological lesion	0.716	0.284	0.000
N01 Rapidly progressive nephritic syndrome	0.716	0.284	0.000
E11.7 With multiple complications	0.716	0.284	0.000
M11 Other crystal arthropathies	0.085	0.284	0.631
M21 Other acquired deformities of limbs	0.716	0.284	0.000
D64.4 Congenital dyserythropoietic anaemia	0.715	0.284	0.000
D64.3 Other sideroblastic anaemias	0.715	0.284	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.715	0.284	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.715	0.284	0.000
D64.0 Hereditary sideroblastic anaemia	0.715	0.284	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.715	0.284	0.000
N04.8 Other	0.715	0.285	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.715	0.285	0.000
N04.6 Dense deposit disease	0.715	0.285	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.715	0.285	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.715	0.285	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.715	0.285	0.000
E34 Other endocrine disorders	0.715	0.285	0.000
B02 Zoster [herpes zoster]	0.714	0.286	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.714	0.286	0.000
I77.0 Arteriovenous fistula, acquired	0.714	0.286	0.000
E22 Hyperfunction of pituitary gland	0.713	0.287	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.001	0.288	0.711
M85 Other disorders of bone density and structure	0.712	0.288	0.000
J92.9 Pleural plaque without asbestos	0.710	0.290	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.709	0.291	0.000
N05.6 Dense deposit disease	0.709	0.291	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.709	0.291	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.709	0.291	0.000
N05.0 Minor glomerular abnormality	0.709	0.291	0.000
H25 Senile cataract	0.709	0.291	0.000
E14.5 With peripheral circulatory complications	0.707	0.293	0.000
D51.2 Transcobalamin II deficiency	0.707	0.293	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.707	0.293	0.000
E31 Polyglandular dysfunction	0.707	0.293	0.000
I77.5 Necrosis of artery	0.706	0.294	0.000
I77.4 Coeliac artery compression syndrome	0.706	0.294	0.000
I77.3 Arterial fibromuscular dysplasia	0.706	0.294	0.000
J41 Simple and mucopurulent chronic bronchitis	0.706	0.294	0.000
G52 Disorders of other cranial nerves	0.704	0.296	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.704	0.296	0.000
I00-I02 Acute rheumatic fever	0.704	0.296	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.004	0.296	0.700
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.703	0.297	0.000
Q35-Q37 Cleft lip and cleft palate	0.703	0.297	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.703	0.297	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.702	0.298	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.702	0.298	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.702	0.298	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.702	0.298	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.702	0.298	0.000
M60 Myositis	0.701	0.299	0.000
N05.8 Other	0.701	0.299	0.000
E10.5 With peripheral circulatory complications	0.700	0.300	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.700	0.300	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.700	0.300	0.000
H25.8 Other senile cataract	0.699	0.301	0.000
B02.9 Zoster without complication	0.699	0.301	0.000
J45.8 Mixed asthma	0.698	0.302	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.698	0.302	0.000
D82 Immunodeficiency associated with other major defects	0.697	0.302	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.697	0.303	0.000
E73 Lactose intolerance	0.696	0.304	0.000
E61 Deficiency of other nutrient elements	0.696	0.304	0.000
H30 Chorioretinal inflammation	0.695	0.305	0.000
H27.0 Aphakia	0.695	0.305	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.694	0.306	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.306	0.694
E13 Other specified diabetes mellitus	0.693	0.307	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.693	0.307	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.692	0.308	0.000
E24 Cushing's syndrome	0.692	0.308	0.000
J43.8 Other emphysema	0.691	0.308	0.000
K75.9 Inflammatory liver disease, unspecified	0.691	0.309	0.000
J43.2 Centrilobular emphysema	0.691	0.309	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.690	0.310	0.000
D86 Sarcoidosis	0.689	0.311	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.689	0.311	0.000
I77.2 Rupture of artery	0.688	0.311	0.000
H34 Retinal vascular occlusions	0.688	0.312	0.000
G11 Hereditary ataxia	0.687	0.313	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.686	0.314	0.000
E10.6 With other specified complications	0.684	0.315	0.000
D81 Combined immunodeficiencies	0.684	0.316	0.000
E06.3 Autoimmune thyroiditis	0.684	0.316	0.000
E89.2 Postprocedural hypoparathyroidism	0.683	0.317	0.000
M35.1 Other overlap syndromes	0.682	0.318	0.000
Q40 Other congenital malformations of upper alimentary tract	0.681	0.319	0.000
E88 Other metabolic disorders	0.681	0.319	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.319	0.680
M71 Other bursopathies	0.680	0.320	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.680	0.320	0.000
Q51 Congenital malformations of uterus and cervix	0.680	0.320	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.680	0.320	0.000
E11.0 With coma	0.679	0.321	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.679	0.321	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.679	0.321	0.000
Q45 Other congenital malformations of digestive system	0.678	0.322	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.678	0.322	0.000
E63 Other nutritional deficiencies	0.678	0.322	0.000
E56 Other vitamin deficiencies	0.678	0.322	0.000
E50 Vitamin A deficiency	0.678	0.322	0.000
E60 Dietary zinc deficiency	0.678	0.322	0.000
E59 Dietary selenium deficiency	0.678	0.322	0.000
E58 Dietary calcium deficiency	0.678	0.322	0.000
E54 Ascorbic acid deficiency	0.678	0.322	0.000
E52 Niacin deficiency [pellagra]	0.678	0.322	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.677	0.323	0.000
N03 Chronic nephritic syndrome	0.677	0.323	0.000
G50.8 Other disorders of trigeminal nerve	0.677	0.323	0.000
D84 Other immunodeficiencies	0.675	0.325	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.674	0.325	0.000
M21.1 Varus deformity, not elsewhere classified	0.674	0.326	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.674	0.326	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.673	0.327	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.673	0.327	0.000
N27 Small kidney of unknown cause	0.672	0.328	0.000
I07 Rheumatic tricuspid valve diseases	0.671	0.328	0.000
G51.4 Facial myokymia	0.671	0.329	0.000
G51.2 Melkersson's syndrome	0.671	0.329	0.000
G51.1 Geniculate ganglionitis	0.671	0.329	0.000
Q63 Other congenital malformations of kidney	0.671	0.329	0.000
D83.9 Common variable immunodeficiency, unspecified	0.670	0.330	0.000
I74.5 Embolism and thrombosis of iliac artery	0.670	0.330	0.000
E78.1 Pure hyperglyceridaemia	0.669	0.331	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.668	0.331	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.668	0.331	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.668	0.331	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.668	0.331	0.000
G12 Spinal muscular atrophy and related syndromes	0.668	0.332	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.332	0.668
E11.6 With other specified complications	0.667	0.333	0.000
K77 Liver disorders in diseases classified elsewhere	0.667	0.333	0.000
K71 Toxic liver disease	0.667	0.333	0.000
K75.2 Nonspecific reactive hepatitis	0.665	0.335	0.000
K75.1 Phlebitis of portal vein	0.665	0.335	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.665	0.335	0.000
E32 Diseases of thymus	0.665	0.335	0.000
E30 Disorders of puberty, not elsewhere classified	0.665	0.335	0.000
E25 Adrenogenital disorders	0.665	0.335	0.000
M86 Osteomyelitis	0.664	0.336	0.000
K72 Hepatic failure, not elsewhere classified	0.664	0.336	0.000
E06.9 Thyroiditis, unspecified	0.663	0.337	0.000
Q54.1 Hypospadias, penile	0.663	0.337	0.000
E79 Disorders of purine and pyrimidine metabolism	0.663	0.337	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.663	0.337	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.663	0.337	0.000
M35.5 Multifocal fibrosclerosis	0.663	0.337	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.663	0.337	0.000
E84 Cystic fibrosis	0.662	0.337	0.000
E77 Disorders of glycoprotein metabolism	0.662	0.337	0.000
E76 Disorders of glycosaminoglycan metabolism	0.662	0.337	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.662	0.337	0.000
E72 Other disorders of amino-acid metabolism	0.662	0.337	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.662	0.337	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.662	0.337	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.662	0.338	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.661	0.339	0.000
M88 Paget's disease of bone [osteitis deformans]	0.660	0.340	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.660	0.340	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.659	0.341	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.659	0.341	0.000
E89.5 Postprocedural testicular hypofunction	0.659	0.341	0.000
E89.4 Postprocedural ovarian failure	0.659	0.341	0.000
E89.1 Postprocedural hypoinsulinaemia	0.659	0.341	0.000
N26 Unspecified contracted kidney	0.658	0.342	0.000
G00 Bacterial meningitis, not elsewhere classified	0.656	0.344	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.096	0.345	0.559
M08 Juvenile arthritis	0.096	0.345	0.559
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.346	0.654
M76 Enthesopathies of lower limb, excluding foot	0.654	0.346	0.000
E40-E46 Malnutrition	0.654	0.346	0.000
G51.8 Other disorders of facial nerve	0.653	0.347	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.651	0.349	0.000
A15-A19 Tuberculosis	0.650	0.350	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.650	0.350	0.000
I79.1 Aortitis in diseases classified elsewhere	0.650	0.350	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.650	0.350	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.650	0.350	0.000
G59.8 Other mononeuropathies in diseases classified elsewhere	0.650	0.350	0.000
E78.4 Other hyperlipidaemia	0.649	0.350	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.649	0.351	0.000
E07.9 Disorder of thyroid, unspecified	0.648	0.352	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.648	0.352	0.000
E78.8 Other disorders of lipoprotein metabolism	0.647	0.353	0.000
E27.5 Adrenomedullary hyperfunction	0.646	0.354	0.000
E27.0 Other adrenocortical overactivity	0.646	0.354	0.000
E11.2 With renal complications	0.646	0.354	0.000
M06.8 Other specified rheumatoid arthritis	0.003	0.354	0.643
M06.2 Rheumatoid bursitis	0.003	0.354	0.643
M06.1 Adult-onset Still's disease	0.003	0.354	0.643
M85.6 Other cyst of bone	0.644	0.356	0.000
Chapter XXII Codes for special purposes	0.644	0.356	0.000
Q80-Q89 Other congenital malformations	0.644	0.356	0.000
M72.5 Fasciitis, not elsewhere classified	0.643	0.357	0.000
E74 Other disorders of carbohydrate metabolism	0.643	0.357	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.643	0.357	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.642	0.358	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.642	0.358	0.000
Q55 Other congenital malformations of male genital organs	0.641	0.359	0.000
M33 Dermatopolymyositis	0.641	0.359	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.640	0.359	0.000
H34.8 Other retinal vascular occlusions	0.640	0.360	0.000
M17 Gonarthrosis [arthrosis of knee]	0.640	0.360	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.640	0.360	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.361	0.639
D50.1 Sideropenic dysphagia	0.638	0.362	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.638	0.362	0.000
J45.0 Predominantly allergic asthma	0.638	0.362	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.637	0.363	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.637	0.363	0.000
B07 Viral warts	0.637	0.363	0.000
E55.9 Vitamin D deficiency, unspecified	0.635	0.364	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.635	0.365	0.000
M15.0 Primary generalised (osteo)arthrosis	0.635	0.365	0.000
M15.3 Secondary multiple arthrosis	0.635	0.365	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.634	0.365	0.000
M83 Adult osteomalacia	0.633	0.367	0.000
J43.1 Panlobular emphysema	0.632	0.368	0.000
J43.0 MacLeod's syndrome	0.632	0.368	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.632	0.368	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.632	0.368	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.632	0.368	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.632	0.368	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.632	0.368	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.632	0.368	0.000
M50-M54 Other dorsopathies	0.631	0.369	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.631	0.369	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.630	0.369	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.630	0.370	0.000
M34 Systemic sclerosis	0.629	0.371	0.000
I06 Rheumatic aortic valve diseases	0.629	0.371	0.000
M72.9 Fibroblastic disorder, unspecified	0.629	0.371	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations