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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2050190
log Bayes Factor = 201.518
Chromosome 6   position 32,339,076  (GRCh37) Explore rs2050190 on Ensembl!
Variant rs2050190 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E27 Other disorders of adrenal gland
1.000 0.000 0.000
E10.9 Without complications
0.998 0.002 0.000
E27.1 Primary adrenocortical insufficiency
0.998 0.002 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.002 0.998
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.004 0.996
M05 Seropositive rheumatoid arthritis
0.001 0.006 0.993
E03 Other hypothyroidism
0.994 0.006 0.000
M05-M14 Inflammatory polyarthropathies
0.003 0.007 0.990
M20.1 Hallux valgus (acquired)
0.000 0.011 0.989
E28 Ovarian dysfunction
0.984 0.016 0.000
M06.3 Rheumatoid nodule
0.000 0.016 0.984
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.017 0.983
E03.9 Hypothyroidism, unspecified
0.982 0.018 0.000
E28.2 Polycystic ovarian syndrome
0.969 0.031 0.000
E10.3 With ophthalmic complications
0.968 0.032 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.041 0.959
N04 Nephrotic syndrome
0.947 0.053 0.000
N04.9 Unspecified
0.947 0.053 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.941 0.059 0.000
N00-N08 Glomerular diseases
0.940 0.060 0.000
N05 Unspecified nephritic syndrome
0.930 0.070 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.928 0.072 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.073 0.927
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.082 0.918
E07 Other disorders of thyroid
0.917 0.083 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.086 0.914
K90 Intestinal malabsorption
0.912 0.088 0.000
E10.1 With ketoacidosis
0.911 0.089 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.908 0.092 0.000
E24 Cushing's syndrome
0.904 0.096 0.000
E21.3 Hyperparathyroidism, unspecified
0.903 0.097 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.902 0.098 0.000
E16 Other disorders of pancreatic internal secretion
0.899 0.101 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.885 0.115 0.000
M20 Acquired deformities of fingers and toes
0.000 0.120 0.880
E07.8 Other specified disorders of thyroid
0.874 0.126 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.127 0.873
K90.9 Intestinal malabsorption, unspecified
0.870 0.130 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.134 0.866
M20.4 Other hammer toe(s) (acquired)
0.000 0.139 0.861
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.142 0.858
E27.3 Drug-induced adrenocortical insufficiency
0.857 0.143 0.000
E50-E64 Other nutritional deficiencies
0.857 0.143 0.000
E27.9 Disorder of adrenal gland, unspecified
0.856 0.144 0.000
E10.2 With renal complications
0.853 0.147 0.000
E16.2 Hypoglycaemia, unspecified
0.846 0.154 0.000
N05.2 Diffuse membranous glomerulonephritis
0.844 0.156 0.000
E14 Unspecified diabetes mellitus
0.841 0.159 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.159 0.841
N05.1 Focal and segmental glomerular lesions
0.835 0.165 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.171 0.828
N04.2 Diffuse membranous glomerulonephritis
0.823 0.177 0.000
E06 Thyroiditis
0.814 0.186 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.190 0.809
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.194 0.806
N04.1 Focal and segmental glomerular lesions
0.805 0.195 0.000
E23 Hypofunction and other disorders of pituitary gland
0.804 0.196 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.202 0.798
E10.7 With multiple complications
0.793 0.207 0.000
E53 Deficiency of other B group vitamins
0.791 0.209 0.000
M20.3 Other deformity of hallux (acquired)
0.000 0.214 0.786
E31 Polyglandular dysfunction
0.785 0.215 0.000
M14 Arthropathies in other diseases classified elsewhere
0.002 0.216 0.782
N04.8 Other
0.782 0.218 0.000
E28.3 Primary ovarian failure
0.780 0.220 0.000
N05.9 Unspecified
0.772 0.228 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.228 0.771
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.768 0.232 0.000
E03.8 Other specified hypothyroidism
0.765 0.235 0.000
E53.8 Deficiency of other specified B group vitamins
0.763 0.237 0.000
E20 Hypoparathyroidism
0.760 0.240 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.243 0.757
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.756 0.244 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.250 0.749
E24.0 Pituitary-dependent Cushing's disease
0.749 0.251 0.000
E27.8 Other specified disorders of adrenal gland
0.745 0.255 0.000
E24.2 Drug-induced Cushing's syndrome
0.745 0.255 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.258 0.742
N05.8 Other
0.740 0.260 0.000
E16.1 Other hypoglycaemia
0.736 0.264 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.735 0.265 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.276 0.724
E27.2 Addisonian crisis
0.723 0.277 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.278 0.722
E24.9 Cushing's syndrome, unspecified
0.722 0.278 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E25 Adrenogenital disorders
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E27.5 Adrenomedullary hyperfunction
0.717 0.283 0.000
E27.0 Other adrenocortical overactivity
0.717 0.283 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.284 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.284 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.284 0.716
E10.0 With coma
0.713 0.287 0.000
M05.8 Other seropositive rheumatoid arthritis
0.001 0.287 0.712
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.001 0.287 0.712
M05.1 Rheumatoid lung disease
0.001 0.287 0.712
M05.0 Felty's syndrome
0.001 0.287 0.712
E03.5 Myxoedema coma
0.713 0.287 0.000
E03.4 Atrophy of thyroid (acquired)
0.713 0.287 0.000
E03.3 Postinfectious hypothyroidism
0.713 0.287 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.002 0.288 0.710
M08 Juvenile arthritis
0.002 0.288 0.710
M05.2 Rheumatoid vasculitis
0.001 0.291 0.707
E28.9 Ovarian dysfunction, unspecified
0.706 0.294 0.000
E28.8 Other ovarian dysfunction
0.706 0.294 0.000
E28.1 Androgen excess
0.706 0.294 0.000
E28.0 Oestrogen excess
0.706 0.294 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.294 0.706
M06.38 Rheumatoid nodule (Other)
0.000 0.294 0.706
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.294 0.706
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.294 0.706
M06.33 Rheumatoid nodule (Forearm)
0.000 0.294 0.706
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.294 0.706
M12 Other specific arthropathies
0.002 0.295 0.703
E02 Subclinical iodine-deficiency hypothyroidism
0.700 0.300 0.000
E21.2 Other hyperparathyroidism
0.698 0.302 0.000
E51 Thiamine deficiency
0.696 0.304 0.000
N03 Chronic nephritic syndrome
0.694 0.305 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.691 0.309 0.000
E06.3 Autoimmune thyroiditis
0.687 0.313 0.000
E14.3 With ophthalmic complications
0.685 0.315 0.000
E14.8 With unspecified complications
0.685 0.315 0.000
N04.0 Minor glomerular abnormality
0.684 0.316 0.000
E34 Other endocrine disorders
0.683 0.316 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.679 0.321 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.679 0.321 0.000
N04.6 Dense deposit disease
0.679 0.321 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.679 0.321 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.679 0.321 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.679 0.321 0.000
E15 Nondiabetic hypoglycaemic coma
0.675 0.325 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.674 0.326 0.000
N06 Isolated proteinuria with specified morphological lesion
0.674 0.326 0.000
N01 Rapidly progressive nephritic syndrome
0.674 0.326 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.673 0.326 0.000
E23.6 Other disorders of pituitary gland
0.672 0.328 0.000
N00 Acute nephritic syndrome
0.672 0.328 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.671 0.329 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.666 0.333 0.000
N05.6 Dense deposit disease
0.666 0.333 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.666 0.333 0.000
N05.0 Minor glomerular abnormality
0.666 0.333 0.000
E21.4 Other specified disorders of parathyroid gland
0.666 0.334 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.335 0.665
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.335 0.665
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.335 0.665
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.335 0.665
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.335 0.665
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.335 0.665
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.335 0.665
E63 Other nutritional deficiencies
0.659 0.341 0.000
L40.9 Psoriasis, unspecified
0.659 0.341 0.000
E14.1 With ketoacidosis
0.658 0.342 0.000
E07.1 Dyshormogenetic goitre
0.657 0.343 0.000
E07.0 Hypersecretion of calcitonin
0.657 0.343 0.000
L40 Psoriasis
0.657 0.343 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.657 0.343 0.000
L40.5 Arthropathic psoriasis
0.657 0.343 0.000
K90.3 Pancreatic steatorrhoea
0.654 0.346 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.654 0.346 0.000
K90.1 Tropical sprue
0.654 0.346 0.000
E23.7 Disorder of pituitary gland, unspecified
0.652 0.348 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.651 0.349 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.651 0.349 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.651 0.349 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.651 0.349 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.350 0.649
E24.8 Other Cushing's syndrome
0.648 0.352 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.648 0.352 0.000
E24.3 Ectopic ACTH syndrome
0.648 0.352 0.000
E24.1 Nelson's syndrome
0.648 0.352 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.644 0.356 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.644 0.356 0.000
E16.4 Abnormal secretion of gastrin
0.644 0.356 0.000
E16.3 Increased secretion of glucagon
0.644 0.356 0.000
E14.2 Withrenal complications
0.642 0.358 0.000
E03.1 Congenital hypothyroidism without goitre
0.641 0.359 0.000
K90.8 Other intestinal malabsorption
0.641 0.359 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.639 0.361 0.000
M20.0 Deformity of finger(s)
0.000 0.362 0.638
E10.5 With peripheral circulatory complications
0.638 0.362 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.365 0.635
E05.8 Other thyrotoxicosis
0.634 0.366 0.000
E31.0 Autoimmune polyglandular failure
0.630 0.369 0.000
M14.6 Neuropathic arthropathy
0.001 0.371 0.628
E10.6 With other specified complications
0.626 0.374 0.000
E14.4 With neurological complications
0.616 0.384 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.385 0.615
E64 Sequelae of malnutrition and other nutritional deficiencies
0.614 0.386 0.000
E56 Other vitamin deficiencies
0.614 0.386 0.000
E50 Vitamin A deficiency
0.614 0.386 0.000
E60 Dietary zinc deficiency
0.614 0.386 0.000
E59 Dietary selenium deficiency
0.614 0.386 0.000
E54 Ascorbic acid deficiency
0.614 0.386 0.000
E52 Niacin deficiency [pellagra]
0.614 0.386 0.000
N02 Recurrent and persistent haematuria
0.607 0.393 0.000
E23.2 Diabetes insipidus
0.606 0.394 0.000
E14.7 With multiple complications
0.603 0.397 0.000
E14.0 With coma
0.603 0.397 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.600 0.400 0.000
E40-E46 Malnutrition
0.588 0.412 0.000
E20.9 Hypoparathyroidism, unspecified
0.588 0.412 0.000
E14.5 With peripheral circulatory complications
0.587 0.413 0.000
E06.5 Other chronic thyroiditis
0.583 0.416 0.000
E06.4 Drug-induced thyroiditis
0.583 0.416 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.583 0.416 0.000
E06.1 Subacute thyroiditis
0.583 0.416 0.000
E06.0 Acute thyroiditis
0.583 0.416 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.419 0.580
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.419 0.580
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.419 0.580
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.419 0.580
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.419 0.580
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.419 0.580
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.419 0.580
E51.2 Wernicke's encephalopathy
0.580 0.420 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.576 0.424 0.000
E23.1 Drug-induced hypopituitarism
0.576 0.424 0.000
E34.8 Other specified endocrine disorders
0.575 0.425 0.000
E13 Other specified diabetes mellitus
0.572 0.427 0.000
E06.9 Thyroiditis, unspecified
0.572 0.428 0.000
E26 Hyperaldosteronism
0.571 0.429 0.000
E58 Dietary calcium deficiency
0.571 0.429 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.001 0.430 0.569
E53.1 Pyridoxine deficiency
0.567 0.433 0.000
E53.0 Riboflavin deficiency
0.567 0.433 0.000
N03.1 Focal and segmental glomerular lesions
0.563 0.436 0.000
E31.9 Polyglandular dysfunction, unspecified
0.563 0.437 0.000
E31.8 Other polyglandular dysfunction
0.563 0.437 0.000
E31.1 Polyglandular hyperfunction
0.563 0.437 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.001 0.438 0.561
M14.4 Arthropathy in amyloidosis
0.001 0.438 0.561
M14.3 Lipoid dermatoarthritis
0.001 0.438 0.561
M14.1 Crystal arthropathy in other metabolic disorders
0.001 0.438 0.561
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.001 0.438 0.561
N02.2 Diffuse membranous glomerulonephritis
0.562 0.438 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.439 0.561
M14.2 Diabetic arthropathy
0.001 0.439 0.559
E07.9 Disorder of thyroid, unspecified
0.553 0.447 0.000
N03.8 Other
0.547 0.453 0.000
E20.8 Other hypoparathyroidism
0.545 0.455 0.000
E20.1 Pseudohypoparathyroidism
0.545 0.455 0.000
E20.0 Idiopathic hypoparathyroidism
0.545 0.455 0.000
E14.9 Without complications
0.544 0.456 0.000
E70-E90 Metabolic disorders
0.539 0.461 0.000
L40.3 Pustulosis palmaris et plantaris
0.538 0.462 0.000
E29 Testicular dysfunction
0.532 0.467 0.000
G56.0 Carpal tunnel syndrome
0.532 0.468 0.000
L40.1 Generalised pustular psoriasis
0.530 0.470 0.000
E89.0 Postprocedural hypothyroidism
0.528 0.472 0.000
M12.3 Palindromic rheumatism
0.002 0.472 0.527
E55 Vitamin D deficiency
0.528 0.472 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.525 0.475 0.000
M11 Other crystal arthropathies
0.002 0.478 0.520
E14.6 With other specified complications
0.520 0.480 0.000
E63.9 Nutritional deficiency, unspecified
0.517 0.482 0.000
E65-E68 Obesity and other hyperalimentation
0.515 0.485 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E25.9 Adrenogenital disorder, unspecified
0.514 0.486 0.000
E25.8 Other adrenogenital disorders
0.514 0.486 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.514 0.486 0.000
E30.9 Disorder of puberty, unspecified
0.514 0.486 0.000
E30.8 Other disorders of puberty
0.514 0.486 0.000
E30.1 Precocious puberty
0.514 0.486 0.000
E30.0 Delayed puberty
0.514 0.486 0.000
E32.9 Disease of thymus, unspecified
0.514 0.486 0.000
E32.8 Other diseases of thymus
0.514 0.486 0.000
E32.1 Abscess of thymus
0.514 0.486 0.000
E32.0 Persistent hyperplasia of thymus
0.514 0.486 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.514 0.486 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.514 0.486 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.514 0.486 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
G56 Mononeuropathies of upper limb
0.512 0.488 0.000
M05.09 Felty's syndrome (Site unspecified)
0.001 0.489 0.510
M05.08 Felty's syndrome (Other)
0.001 0.489 0.510
M05.07 Felty's syndrome (Ankle and foot)
0.001 0.489 0.510
M05.06 Felty's syndrome (Lower leg)
0.001 0.489 0.510
M05.05 Felty's syndrome (Pelvic region and thigh)
0.001 0.489 0.510
M05.04 Felty's syndrome (Hand)
0.001 0.489 0.510
M05.03 Felty's syndrome (Forearm)
0.001 0.489 0.510
M05.02 Felty's syndrome (Upper arm)
0.001 0.489 0.510
M05.01 Felty's syndrome (Shoulder region)
0.001 0.489 0.510
M05.00 Felty's syndrome (Multiple sites)
0.001 0.489 0.510
M05.19 Rheumatoid lung disease (Site unspecified)
0.001 0.489 0.510
M05.18 Rheumatoid lung disease (Other)
0.001 0.489 0.510
M05.17 Rheumatoid lung disease (Ankle and foot)
0.001 0.489 0.510
M05.16 Rheumatoid lung disease (Lower leg)
0.001 0.489 0.510
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.001 0.489 0.510
M05.14 Rheumatoid lung disease (Hand)
0.001 0.489 0.510
M05.13 Rheumatoid lung disease (Forearm)
0.001 0.489 0.510
M05.12 Rheumatoid lung disease (Upper arm)
0.001 0.489 0.510
M05.11 Rheumatoid lung disease (Shoulder region)
0.001 0.489 0.510
M05.10 Rheumatoid lung disease (Multiple sites)
0.001 0.489 0.510
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.001 0.489 0.510
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.001 0.489 0.510
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.001 0.489 0.510
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.001 0.489 0.510
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.001 0.489 0.510
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.001 0.489 0.510
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.001 0.489 0.510
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.001 0.489 0.510
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.001 0.489 0.510
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.001 0.489 0.510
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.001 0.489 0.510
M05.88 Other seropositive rheumatoid arthritis (Other)
0.001 0.489 0.510
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.001 0.489 0.510
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.001 0.489 0.510
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.001 0.489 0.510
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.001 0.489 0.510
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.001 0.489 0.510
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.001 0.489 0.510
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.001 0.489 0.510
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.001 0.489 0.510
M08.9 Juvenile arthritis, unspecified
0.002 0.489 0.509
M08.8 Other juvenile arthritis
0.002 0.489 0.509
M08.4 Pauciarticular juvenile arthritis
0.002 0.489 0.509
M08.3 Juvenile polyarthritis (seronegative)
0.002 0.489 0.509
M08.2 Juvenile arthritis with systemic onset
0.002 0.489 0.509
M08.1 Juvenile ankylosing spondylitis
0.002 0.489 0.509
M08.0 Juvenile rheumatoid arthritis
0.002 0.489 0.509
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.002 0.489 0.509
M09.2 Juvenile arthritis in ulcerative colitis
0.002 0.489 0.509
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.002 0.489 0.509
M09.0 Juvenile arthritis in psoriasis
0.002 0.489 0.509
G51 Facial nerve disorders
0.509 0.491 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.508 0.492 0.000
M05.28 Rheumatoid vasculitis (Other)
0.001 0.492 0.507
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.001 0.492 0.507
M05.26 Rheumatoid vasculitis (Lower leg)
0.001 0.492 0.507
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.001 0.492 0.507
M05.24 Rheumatoid vasculitis (Hand)
0.001 0.492 0.507
M05.23 Rheumatoid vasculitis (Forearm)
0.001 0.492 0.507
M05.22 Rheumatoid vasculitis (Upper arm)
0.001 0.492 0.507
M05.21 Rheumatoid vasculitis (Shoulder region)
0.001 0.492 0.507
M05.20 Rheumatoid vasculitis (Multiple sites)
0.001 0.492 0.507
L40-L45 Papulosquamous disorders
0.507 0.493 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.002 0.494 0.504
M12.5 Traumatic arthropathy
0.002 0.494 0.504
M12.4 Intermittent hydrarthrosis
0.002 0.494 0.504
M12.1 Kaschin-Beck disease
0.002 0.494 0.504
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.002 0.494 0.504
M05.29 Rheumatoid vasculitis (Site unspecified)
0.001 0.496 0.503
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.503 0.497 0.000
G51.0 Bell's palsy
0.501 0.499 0.000
E22 Hyperfunction of pituitary gland
0.500 0.500 0.000
E51.9 Thiamine deficiency, unspecified
0.499 0.501 0.000
E51.8 Other manifestations of thiamine deficiency
0.499 0.501 0.000
E51.1 Beriberi
0.499 0.501 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.498 0.502 0.000
N03.6 Dense deposit disease
0.498 0.502 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.498 0.502 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.498 0.502 0.000
N03.2 Diffuse membranous glomerulonephritis
0.498 0.502 0.000
N03.0 Minor glomerular abnormality
0.498 0.502 0.000
L40.4 Guttate psoriasis
0.494 0.506 0.000
E34.5 Androgen resistance syndrome
0.490 0.510 0.000
E34.4 Constitutional tall stature
0.490 0.510 0.000
E34.3 Short stature, not elsewhere classified
0.490 0.510 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.490 0.510 0.000
E34.1 Other hypersecretion of intestinal hormones
0.490 0.510 0.000
N01.9 Unspecified
0.483 0.516 0.000
N01.8 Other
0.483 0.516 0.000
N01.7 Diffuse crescentic glomerulonephritis
0.483 0.516 0.000
N01.6 Dense deposit disease
0.483 0.516 0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis
0.483 0.516 0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis
0.483 0.516 0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis
0.483 0.516 0.000
N01.2 Diffuse membranous glomerulonephritis
0.483 0.516 0.000
N01.1 Focal and segmental glomerular lesions
0.483 0.516 0.000
N01.0 Minor glomerular abnormality
0.483 0.516 0.000
N06.9 Unspecified
0.483 0.516 0.000
N06.8 Other
0.483 0.516 0.000
N06.7 Diffuse crescentic glomerulonephritis
0.483 0.516 0.000
N06.6 Dense deposit disease
0.483 0.516 0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis
0.483 0.516 0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis
0.483 0.516 0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis
0.483 0.516 0.000
N06.2 Diffuse membranous glomerulonephritis
0.483 0.516 0.000
N06.1 Focal and segmental glomerular lesions
0.483 0.516 0.000
N06.0 Minor glomerular abnormality
0.483 0.516 0.000
N07.9 Unspecified
0.483 0.516 0.000
N07.8 Other
0.483 0.516 0.000
N07.7 Diffuse crescentic glomerulonephritis
0.483 0.516 0.000
N07.6 Dense deposit disease
0.483 0.516 0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis
0.483 0.516 0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis
0.483 0.516 0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis
0.483 0.516 0.000
N07.2 Diffuse membranous glomerulonephritis
0.483 0.516 0.000
N07.1 Focal and segmental glomerular lesions
0.483 0.516 0.000
N07.0 Minor glomerular abnormality
0.483 0.516 0.000
N00.8 Other
0.481 0.518 0.000
N00.7 Diffuse crescentic glomerulonephritis
0.481 0.518 0.000
N00.6 Dense deposit disease
0.481 0.518 0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis
0.481 0.518 0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis
0.481 0.518 0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis
0.481 0.518 0.000
N00.2 Diffuse membranous glomerulonephritis
0.481 0.518 0.000
N00.1 Focal and segmental glomerular lesions
0.481 0.518 0.000
N00.0 Minor glomerular abnormality
0.481 0.518 0.000
N00.9 Unspecified
0.479 0.521 0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis
0.476 0.524 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.527 0.473
E63.8 Other specified nutritional deficiencies
0.473 0.527 0.000
E63.1 Imbalance of constituents of food intake
0.473 0.527 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.473 0.527 0.000
M12.2 Villonodular synovitis (pigmented)
0.002 0.528 0.470
L40.2 Acrodermatitis continua
0.471 0.529 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.469 0.531 0.000
E88 Other metabolic disorders
0.468 0.532 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.467 0.533 0.000
E10.4 With neurological complications
0.467 0.533 0.000
G51.3 Clonic hemifacial spasm
0.464 0.536 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.462 0.538 0.000
# Top node
0.459 0.541 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.544 0.455
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.544 0.455
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.544 0.455
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.544 0.455
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.544 0.455
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.544 0.455
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.544 0.455
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.544 0.455
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.544 0.455
Q60-Q64 Congenital malformations of the urinary system
0.455 0.545 0.000
Chapter VI Diseases of the nervous system
0.452 0.548 0.000
Q43 Other congenital malformations of intestine
0.451 0.549 0.000
E04 Other non-toxic goitre
0.447 0.553 0.000
E34.0 Carcinoid syndrome
0.446 0.554 0.000
M13 Other arthritis
0.001 0.557 0.442
E21.0 Primary hyperparathyroidism
0.442 0.558 0.000
E50.9 Vitamin A deficiency, unspecified
0.440 0.559 0.000
E50.8 Other manifestations of vitamin A deficiency
0.440 0.559 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.440 0.559 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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