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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2067577
log Bayes Factor = 28.2714
Chromosome 6   position 32,762,484  (GRCh37) Explore rs2067577 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
C44.7 Skin of lower limb, including hip
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
C44.6 Skin of upper limb, including shoulder
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
E10 Insulin-dependent diabetes mellitus
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
E20-E35 Disorders of other endocrine glands
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
E10-E14 Diabetes mellitus
0.000 0.003 0.997
C44.3 Skin of other and unspecified parts of face
0.000 0.004 0.996
L40.9 Psoriasis, unspecified
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.005 0.995
E05.9 Thyrotoxicosis, unspecified
0.000 0.007 0.993
C44.4 Skin of scalp and neck
0.000 0.013 0.987
E23 Hypofunction and other disorders of pituitary gland
0.000 0.013 0.987
L57.0 Actinic keratosis
0.000 0.015 0.985
E27 Other disorders of adrenal gland
0.000 0.023 0.977
C44.2 Skin of ear and external auricular canal
0.000 0.036 0.964
G35-G37 Demyelinating diseases of the central nervous system
0.960 0.040 0.000
G37 Other demyelinating diseases of central nervous system
0.948 0.052 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.058 0.942
E27.1 Primary adrenocortical insufficiency
0.000 0.060 0.940
J45.9 Asthma, unspecified
0.939 0.061 0.000
E23.6 Other disorders of pituitary gland
0.000 0.062 0.938
G37.9 Demyelinating disease of central nervous system, unspecified
0.927 0.073 0.000
E10.2 With renal complications
0.000 0.094 0.906
E24 Cushing's syndrome
0.000 0.100 0.900
E10.5 With peripheral circulatory complications
0.000 0.108 0.892
E10.1 With ketoacidosis
0.000 0.112 0.888
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.131 0.869
G37.8 Other specified demyelinating diseases of central nervous system
0.866 0.134 0.000
L40-L45 Papulosquamous disorders
0.000 0.140 0.860
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.151 0.849
J45 Asthma
0.835 0.165 0.000
E28 Ovarian dysfunction
0.000 0.167 0.833
L40.1 Generalised pustular psoriasis
0.000 0.169 0.831
E10.9 Without complications
0.000 0.170 0.830
L40.3 Pustulosis palmaris et plantaris
0.000 0.170 0.830
C44.0 Skin of lip
0.000 0.185 0.815
J45.0 Predominantly allergic asthma
0.808 0.192 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.195 0.805
E10.0 With coma
0.000 0.216 0.784
G36 Other acute disseminated demyelination
0.781 0.219 0.000
L40.4 Guttate psoriasis
0.000 0.228 0.772
L40.0 Psoriasis vulgaris
0.000 0.228 0.772
E83.1 Disorders of iron metabolism
0.768 0.231 0.000
E29 Testicular dysfunction
0.000 0.232 0.768
E06 Thyroiditis
0.000 0.237 0.763
E13 Other specified diabetes mellitus
0.000 0.238 0.762
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.242 0.758
L43 Lichen planus
0.000 0.247 0.753
E24.0 Pituitary-dependent Cushing's disease
0.000 0.253 0.747
E23.0 Hypopituitarism
0.000 0.254 0.746
E24.2 Drug-induced Cushing's syndrome
0.000 0.260 0.740
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.278 0.722
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
E10.7 With multiple complications
0.000 0.284 0.715
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.285 0.715
E32 Diseases of thymus
0.000 0.285 0.715
E31 Polyglandular dysfunction
0.000 0.285 0.715
E30 Disorders of puberty, not elsewhere classified
0.000 0.285 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E24.9 Cushing's syndrome, unspecified
0.000 0.286 0.714
E26 Hyperaldosteronism
0.000 0.289 0.711
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.293 0.707
E23.1 Drug-induced hypopituitarism
0.000 0.293 0.707
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.294 0.706
E27.5 Adrenomedullary hyperfunction
0.000 0.300 0.700
E27.0 Other adrenocortical overactivity
0.000 0.300 0.700
E28.2 Polycystic ovarian syndrome
0.000 0.303 0.697
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.306 0.694
G37.5 Concentric sclerosis [Balo]
0.679 0.320 0.000
G37.4 Subacute necrotising myelitis
0.679 0.320 0.000
G37.2 Central pontine myelinolysis
0.679 0.320 0.000
G37.1 Central demyelination of corpus callosum
0.679 0.320 0.000
G37.0 Diffuse sclerosis
0.679 0.320 0.000
E25 Adrenogenital disorders
0.000 0.326 0.674
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.329 0.671
E05.8 Other thyrotoxicosis
0.000 0.332 0.668
E34 Other endocrine disorders
0.000 0.334 0.666
E10.4 With neurological complications
0.000 0.341 0.659
E06.3 Autoimmune thyroiditis
0.000 0.345 0.655
L43.9 Lichen planus, unspecified
0.000 0.346 0.654
E27.2 Addisonian crisis
0.000 0.347 0.653
G36.0 Neuromyelitis optica [Devic]
0.653 0.347 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.347 0.653
E40-E46 Malnutrition
0.000 0.350 0.650
E23.2 Diabetes insipidus
0.000 0.351 0.649
E27.9 Disorder of adrenal gland, unspecified
0.000 0.353 0.647
E10.6 With other specified complications
0.000 0.353 0.647
E27.8 Other specified disorders of adrenal gland
0.000 0.354 0.646
E24.8 Other Cushing's syndrome
0.000 0.355 0.645
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.355 0.645
E24.3 Ectopic ACTH syndrome
0.000 0.355 0.645
E24.1 Nelson's syndrome
0.000 0.355 0.645
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.361 0.639
J45.8 Mixed asthma
0.636 0.364 0.000
E04 Other non-toxic goitre
0.000 0.364 0.636
E28.3 Primary ovarian failure
0.000 0.373 0.627
J45.1 Nonallergic asthma
0.620 0.380 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.383 0.617
L44 Other papulosquamous disorders
0.000 0.383 0.616
L41 Parapsoriasis
0.000 0.383 0.616
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.383 0.616
L57.5 Actinic granuloma
0.000 0.391 0.609
L57.3 Poikiloderma of Civatte
0.000 0.391 0.609
L57.2 Cutis rhomboidalis nuchae
0.000 0.391 0.609
L57.1 Actinic reticuloid
0.000 0.391 0.609
E70-E90 Metabolic disorders
0.000 0.391 0.609
E29.1 Testicular hypofunction
0.000 0.397 0.603
E20 Hypoparathyroidism
0.000 0.401 0.599
E28.9 Ovarian dysfunction, unspecified
0.000 0.403 0.597
E28.8 Other ovarian dysfunction
0.000 0.403 0.597
E28.1 Androgen excess
0.000 0.403 0.597
E28.0 Oestrogen excess
0.000 0.403 0.597
E11.3 With ophthalmic complications
0.000 0.408 0.592
E10.8 With unspecified complications
0.000 0.410 0.590
L43.8 Other lichen planus
0.000 0.412 0.588
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.415 0.585
M07.3 Other psoriatic arthropathies
0.000 0.415 0.585
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.419 0.581
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.421 0.579
E13.9 Without complications
0.000 0.421 0.579
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.422 0.578
E04.0 Non-toxic diffuse goitre
0.000 0.427 0.573
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.430 0.570
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.569 0.431 0.000
E13.3 With ophthalmic complications
0.000 0.437 0.563
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.437 0.563
E06.5 Other chronic thyroiditis
0.000 0.439 0.561
G36.9 Acute disseminated demyelination, unspecified
0.560 0.440 0.000
G36.8 Other specified acute disseminated demyelination
0.560 0.440 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.560 0.440 0.000
E65 Localised adiposity
0.000 0.446 0.554
E29.9 Testicular dysfunction, unspecified
0.000 0.449 0.551
E29.8 Other testicular dysfunction
0.000 0.449 0.551
E29.0 Testicular hyperfunction
0.000 0.449 0.551
E34.8 Other specified endocrine disorders
0.000 0.452 0.547
E06.4 Drug-induced thyroiditis
0.000 0.453 0.547
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.453 0.547
E06.0 Acute thyroiditis
0.000 0.453 0.547
E13.8 With unspecified complications
0.000 0.454 0.546
E13.7 With multiple complications
0.000 0.454 0.546
E13.6 With other specified complications
0.000 0.454 0.546
E13.5 With peripheral circulatory complications
0.000 0.454 0.546
E13.4 With neurological complications
0.000 0.454 0.546
E13.2 With renal complications
0.000 0.454 0.546
E13.1 With ketoacidosis
0.000 0.454 0.546
E13.0 With coma
0.000 0.454 0.546
E89.0 Postprocedural hypothyroidism
0.000 0.454 0.546
L55 Sunburn
0.000 0.456 0.543
E78.5 Hyperlipidaemia, unspecified
0.000 0.458 0.542
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.460 0.540
L43.3 Subacute (active) lichen planus
0.000 0.460 0.540
L43.2 Lichenoid drug reaction
0.000 0.460 0.540
L43.1 Bullous lichen planus
0.000 0.460 0.540
L43.0 Hypertrophic lichen planus
0.000 0.460 0.540
E78.2 Mixed hyperlipidaemia
0.000 0.463 0.537
E06.9 Thyroiditis, unspecified
0.000 0.463 0.537
E22 Hyperfunction of pituitary gland
0.000 0.464 0.536
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.464 0.535
E21.3 Hyperparathyroidism, unspecified
0.000 0.466 0.534
L42 Pityriasis rosea
0.000 0.473 0.527
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.479 0.521
E78.6 Lipoprotein deficiency
0.000 0.482 0.518
E30.9 Disorder of puberty, unspecified
0.000 0.487 0.513
E30.8 Other disorders of puberty
0.000 0.487 0.513
E30.1 Precocious puberty
0.000 0.487 0.513
E30.0 Delayed puberty
0.000 0.487 0.513
E31.9 Polyglandular dysfunction, unspecified
0.000 0.487 0.513
E31.8 Other polyglandular dysfunction
0.000 0.487 0.513
E31.1 Polyglandular hyperfunction
0.000 0.487 0.513
E31.0 Autoimmune polyglandular failure
0.000 0.487 0.513
E32.9 Disease of thymus, unspecified
0.000 0.487 0.513
E32.8 Other diseases of thymus
0.000 0.487 0.513
E32.1 Abscess of thymus
0.000 0.487 0.513
E32.0 Persistent hyperplasia of thymus
0.000 0.487 0.513
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.487 0.513
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.487 0.513
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.487 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E26.9 Hyperaldosteronism, unspecified
0.000 0.490 0.509
E26.8 Other hyperaldosteronism
0.000 0.490 0.509
E26.1 Secondary hyperaldosteronism
0.000 0.490 0.509
L40.8 Other psoriasis
0.000 0.494 0.506
E15 Nondiabetic hypoglycaemic coma
0.000 0.494 0.506
E26.0 Primary hyperaldosteronism
0.000 0.495 0.505
L58 Radiodermatitis
0.000 0.501 0.499
E16 Other disorders of pancreatic internal secretion
0.000 0.504 0.496
E11.0 With coma
0.000 0.504 0.496
E88 Other metabolic disorders
0.000 0.506 0.494
L10-L14 Bullous disorders
0.000 0.508 0.492
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.509 0.491
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.511 0.488
E78.1 Pure hyperglyceridaemia
0.000 0.512 0.488
E21.2 Other hyperparathyroidism
0.000 0.516 0.484
E25.9 Adrenogenital disorder, unspecified
0.000 0.517 0.483
E25.8 Other adrenogenital disorders
0.000 0.517 0.483
E21.4 Other specified disorders of parathyroid gland
0.000 0.519 0.481
E34.5 Androgen resistance syndrome
0.000 0.522 0.478
E34.4 Constitutional tall stature
0.000 0.522 0.478
E34.3 Short stature, not elsewhere classified
0.000 0.522 0.478
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.522 0.478
E34.1 Other hypersecretion of intestinal hormones
0.000 0.522 0.478
E11.2 With renal complications
0.000 0.525 0.475
E79 Disorders of purine and pyrimidine metabolism
0.000 0.525 0.475
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.529 0.471
E67 Other hyperalimentation
0.000 0.532 0.468
E68 Sequelae of hyperalimentation
0.000 0.532 0.468
E07 Other disorders of thyroid
0.000 0.533 0.467
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.534 0.466
E45 Retarded development following protein-energy malnutrition
0.000 0.534 0.466
E43 Unspecified severe protein-energy malnutrition
0.000 0.534 0.466
E42 Marasmic kwashiorkor
0.000 0.534 0.466
E41 Nutritional marasmus
0.000 0.534 0.466
E40 Kwashiorkor
0.000 0.534 0.466
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.536 0.464
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.537 0.462
E04.2 Non-toxic multinodular goitre
0.000 0.543 0.457
E04.8 Other specified non-toxic goitre
0.000 0.544 0.456
L57.4 Cutis laxa senilis
0.000 0.556 0.444
E11.7 With multiple complications
0.000 0.557 0.443
L41.9 Parapsoriasis, unspecified
0.000 0.558 0.442
L41.8 Other parapsoriasis
0.000 0.558 0.442
L41.5 Retiform parapsoriasis
0.000 0.558 0.442
L41.4 Large plaque parapsoriasis
0.000 0.558 0.442
L41.3 Small plaque parapsoriasis
0.000 0.558 0.442
L41.2 Lymphomatoid papulosis
0.000 0.558 0.442
L41.1 Pityriasis lichenoides chronica
0.000 0.558 0.442
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.558 0.442
L44.9 Papulosquamous disorder, unspecified
0.000 0.558 0.442
L44.8 Other specified papulosquamous disorders
0.000 0.558 0.442
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.558 0.442
L44.3 Lichen ruber moniliformis
0.000 0.558 0.442
L44.2 Lichen striatus
0.000 0.558 0.442
L44.1 Lichen nitidus
0.000 0.558 0.442
L44.0 Pityriasis rubra pilaris
0.000 0.558 0.442
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.558 0.442
E11.6 With other specified complications
0.000 0.559 0.441
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.560 0.440
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.561 0.439
E84 Cystic fibrosis
0.000 0.562 0.438
E77 Disorders of glycoprotein metabolism
0.000 0.563 0.436
E76 Disorders of glycosaminoglycan metabolism
0.000 0.563 0.436
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.563 0.436
E70 Disorders of aromatic amino-acid metabolism
0.000 0.563 0.436
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.563 0.436
E20.1 Pseudohypoparathyroidism
0.000 0.570 0.429
E20.0 Idiopathic hypoparathyroidism
0.000 0.570 0.429
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.574 0.426
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.578 0.422
M07.38 Other psoriatic arthropathies (Other)
0.000 0.581 0.419
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.581 0.419
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.581 0.419
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.581 0.419
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.581 0.419
E06.1 Subacute thyroiditis
0.000 0.582 0.417
E34.9 Endocrine disorder, unspecified
0.000 0.584 0.416
L56.3 Solar urticaria
0.000 0.585 0.415
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.585 0.415
L56.1 Drug photoallergic response
0.000 0.585 0.415
L56.0 Drug phototoxic response
0.000 0.585 0.415
E11.8 With unspecified complications
0.000 0.586 0.414
E88.3 Tumour lysis syndrome
0.000 0.589 0.411
E89.3 Postprocedural hypopituitarism
0.000 0.590 0.410
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.591 0.409
E89.5 Postprocedural testicular hypofunction
0.000 0.591 0.409
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.592 0.407
E88.8 Other specified metabolic disorders
0.000 0.593 0.407
C44.5 Skin of trunk
0.000 0.595 0.405
E46 Unspecified protein-energy malnutrition
0.000 0.600 0.400
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.604 0.396
E04.9 Non-toxic goitre, unspecified
0.000 0.605 0.395
E89.4 Postprocedural ovarian failure
0.000 0.606 0.394
E20.9 Hypoparathyroidism, unspecified
0.000 0.608 0.392
L55.9 Sunburn, unspecified
0.000 0.610 0.390
L55.8 Other sunburn
0.000 0.610 0.390
L55.2 Sunburn of third degree
0.000 0.610 0.390
L55.1 Sunburn of second degree
0.000 0.610 0.390
L55.0 Sunburn of first degree
0.000 0.610 0.390
E78.4 Other hyperlipidaemia
0.000 0.610 0.389
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.611 0.389
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.612 0.387
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.612 0.387
E22.1 Hyperprolactinaemia
0.000 0.614 0.386
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.616 0.384
E22.8 Other hyperfunction of pituitary gland
0.000 0.616 0.384
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.616 0.384
E89.1 Postprocedural hypoinsulinaemia
0.000 0.618 0.382
E34.0 Carcinoid syndrome
0.000 0.618 0.381
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.621 0.379
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.622 0.378
L56.4 Polymorphous light eruption
0.000 0.624 0.376
E78.3 Hyperchylomicronaemia
0.000 0.624 0.375
E72 Other disorders of amino-acid metabolism
0.000 0.625 0.375
L12 Pemphigoid
0.000 0.628 0.372
E74 Other disorders of carbohydrate metabolism
0.000 0.629 0.371
E73 Lactose intolerance
0.000 0.629 0.371
E78.8 Other disorders of lipoprotein metabolism
0.000 0.634 0.366
E20.8 Other hypoparathyroidism
0.000 0.635 0.365
E85 Amyloidosis
0.000 0.635 0.365
E89.2 Postprocedural hypoparathyroidism
0.000 0.637 0.363
L58.1 Chronic radiodermatitis
0.000 0.642 0.358
L58.0 Acute radiodermatitis
0.000 0.642 0.358
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.642 0.357
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.644 0.356
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.644 0.356
E16.4 Abnormal secretion of gastrin
0.000 0.644 0.356
E16.3 Increased secretion of glucagon
0.000 0.644 0.356
E80.4 Gilbert's syndrome
0.000 0.644 0.356
E21.0 Primary hyperparathyroidism
0.000 0.647 0.353
L10 Pemphigus
0.000 0.647 0.352
L14 Bullous disorders in diseases classified elsewhere
0.000 0.647 0.352
L11 Other acantholytic disorders
0.000 0.649 0.351
E88.2 Lipomatosis, not elsewhere classified
0.000 0.649 0.351
E11.5 With peripheral circulatory complications
0.000 0.653 0.347
E16.1 Other hypoglycaemia
0.000 0.653 0.346
E88.9 Metabolic disorder, unspecified
0.000 0.657 0.343
E11.1 With ketoacidosis
0.000 0.657 0.343
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.657 0.343
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.659 0.340
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.659 0.340
E79.1 Lesch-Nyhan syndrome
0.000 0.659 0.340
E67.8 Other specified hyperalimentation
0.000 0.664 0.336
E67.3 Hypervitaminosis D
0.000 0.664 0.336
E67.2 Megavitamin-B6 syndrome
0.000 0.664 0.336
E67.1 Hypercarotenaemia
0.000 0.664 0.336
E67.0 Hypervitaminosis A
0.000 0.664 0.336
E07.1 Dyshormogenetic goitre
0.000 0.665 0.335
E07.0 Hypersecretion of calcitonin
0.000 0.665 0.335
E44.1 Mild protein-energy malnutrition
0.000 0.666 0.334
E44.0 Moderate protein-energy malnutrition
0.000 0.666 0.334
E80.6 Other disorders of bilirubin metabolism
0.000 0.669 0.331
L13 Other bullous disorders
0.000 0.675 0.325
E84.9 Cystic fibrosis, unspecified
0.000 0.684 0.316
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.685 0.315
E80.5 Crigler-Najjar syndrome
0.000 0.685 0.315
E80.3 Defects of catalase and peroxydase
0.000 0.685 0.315
E80.0 Hereditary erythropoietic porphyria
0.000 0.685 0.315
E84.8 Cystic fibrosis with other manifestations
0.000 0.686 0.314
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.686 0.314
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.686 0.314
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.686 0.314
L58.9 Radiodermatitis, unspecified
0.000 0.686 0.313
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.687 0.313
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.687 0.313
E70.3 Albinism
0.000 0.687 0.313
E70.2 Disorders of tyrosine metabolism
0.000 0.687 0.313
E70.1 Other hyperphenylalaninaemias
0.000 0.687 0.313
E70.0 Classical phenylketonuria
0.000 0.687 0.313
E71.3 Disorders of fatty-acid metabolism
0.000 0.687 0.313
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.687 0.313
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.687 0.313
E71.0 Maple-syrup-urine disease
0.000 0.687 0.313
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.687 0.313
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.687 0.313
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.687 0.313
E76.2 Other mucopolysaccharidoses
0.000 0.687 0.313
E76.1 Mucopolysaccharidosis, type II
0.000 0.687 0.313
E76.0 Mucopolysaccharidosis, type I
0.000 0.687 0.313
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.687 0.313
E77.8 Other disorders of glycoprotein metabolism
0.000 0.687 0.313
E77.1 Defects in glycoprotein degradation
0.000 0.687 0.313
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.687 0.313
E50-E64 Other nutritional deficiencies
0.000 0.688 0.312
E16.2 Hypoglycaemia, unspecified
0.000 0.689 0.311
E07.8 Other specified disorders of thyroid
0.000 0.692 0.308
E75.6 Lipid storage disorder, unspecified
0.000 0.699 0.301
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.699 0.301
E75.3 Sphingolipidosis, unspecified
0.000 0.699 0.301
E75.1 Other gangliosidosis
0.000 0.699 0.301
E75.0 GM2 gangliosidosis
0.000 0.699 0.301
L60-L75 Disorders of skin appendages
0.000 0.699 0.301
E80.1 Porphyria cutanea tarda
0.000 0.704 0.296
E75.2 Other sphingolipidosis
0.000 0.704 0.295
E75.5 Other lipid storage disorders
0.000 0.711 0.289
E03 Other hypothyroidism
0.000 0.714 0.286
L12.9 Pemphigoid, unspecified
0.000 0.714 0.286
E85.4 Organ-limited amyloidosis
0.000 0.720 0.280
E22.0 Acromegaly and pituitary gigantism
0.000 0.728 0.272
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.731 0.269
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.731 0.269
E72.5 Disorders of glycine metabolism
0.000 0.731 0.269
E72.4 Disorders of ornithine metabolism
0.000 0.731 0.269
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.731 0.269
E72.2 Disorders of urea cycle metabolism
0.000 0.731 0.269
L12.0 Bullous pemphigoid
0.000 0.732 0.268
L12.1 Cicatricial pemphigoid
0.000 0.732 0.267
L12.8 Other pemphigoid
0.000 0.733 0.267
L12.3 Acquired epidermolysis bullosa
0.000 0.733 0.267
L12.2 Chronic bullous disease of childhood
0.000 0.733 0.267
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.734 0.266
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.734 0.266
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.734 0.266
E74.2 Disorders of galactose metabolism
0.000 0.734 0.266
E74.1 Disorders of fructose metabolism
0.000 0.734 0.266
E74.0 Glycogen storage disease
0.000 0.734 0.266
E73.8 Other lactose intolerance
0.000 0.734 0.266
E73.1 Secondary lactase deficiency
0.000 0.734 0.266
E73.0 Congenital lactase deficiency
0.000 0.734 0.266
E85.9 Amyloidosis, unspecified
0.000 0.734 0.266
L71 Rosacea
0.000 0.735 0.265
E72.0 Disorders of amino-acid transport
0.000 0.735 0.264
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.738 0.262
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.738 0.262
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.738 0.262
E83 Disorders of mineral metabolism
0.072 0.740 0.187
E80.2 Other porphyria
0.000 0.743 0.256
L11.0 Acquired keratosis follicularis
0.000 0.745 0.255
L10.9 Pemphigus, unspecified
0.000 0.747 0.253
L10.8 Other pemphigus
0.000 0.747 0.253
L10.5 Drug-induced pemphigus
0.000 0.747 0.253
L10.4 Pemphigus erythematosus
0.000 0.747 0.253
L10.3 Brazilian pemphigus [fogo selvagem]
0.000 0.747 0.253
L10.2 Pemphigus foliaceus
0.000 0.747 0.253
L10.1 Pemphigus vegetans
0.000 0.747 0.253
L10.0 Pemphigus vulgaris
0.000 0.747 0.253
L11.9 Acantholytic disorder, unspecified
0.000 0.748 0.252
L11.8 Other specified acantholytic disorders
0.000 0.748 0.252
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.753 0.247
L11.1 Transient acantholytic dermatosis [Grover]
0.000 0.753 0.247
E51 Thiamine deficiency
0.000 0.756 0.244
L71.9 Rosacea, unspecified
0.000 0.762 0.238
E56 Other vitamin deficiencies
0.000 0.765 0.234
L68 Hypertrichosis
0.000 0.766 0.234
L13.9 Bullous disorder, unspecified
0.000 0.767 0.233
L13.8 Other specified bullous disorders
0.000 0.767 0.233
L13.1 Subcorneal pustular dermatitis
0.000 0.767 0.233
L66 Cicatricial alopecia [scarring hair loss]
0.000 0.770 0.229
L50-L54 Urticaria and erythema
0.000 0.772 0.228
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.776 0.224
E50 Vitamin A deficiency
0.000 0.776 0.224
E60 Dietary zinc deficiency
0.000 0.776 0.224
E59 Dietary selenium deficiency
0.000 0.776 0.224
E52 Niacin deficiency [pellagra]
0.000 0.776 0.224
L60 Nail disorders
0.000 0.776 0.224
E85.8 Other amyloidosis
0.000 0.777 0.223
M07 Psoriatic and enteropathic arthropathies
0.000 0.777 0.222
L75 Apocrine sweat disorders
0.000 0.784 0.216
L74 Eccrine sweat disorders
0.000 0.784 0.216
L67 Hair colour and hair shaft abnormalities
0.000 0.784 0.216
L64 Androgenic alopecia
0.000 0.784 0.216
L62 Nail disorders in diseases classified elsewhere
0.000 0.784 0.216
L63 Alopecia areata
0.000 0.784 0.216
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.786 0.213
E63 Other nutritional deficiencies
0.000 0.787 0.213
L60.9 Nail disorder, unspecified
0.000 0.788 0.212
E85.3 Secondary systemic amyloidosis
0.000 0.794 0.206
L13.0 Dermatitis herpetiformis
0.000 0.795 0.205
E03.5 Myxoedema coma
0.000 0.795 0.205
E03.4 Atrophy of thyroid (acquired)
0.000 0.795 0.205
E03.3 Postinfectious hypothyroidism
0.000 0.795 0.205
E55 Vitamin D deficiency
0.000 0.797 0.203
E54 Ascorbic acid deficiency
0.000 0.798 0.202
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.799 0.201
E03.1 Congenital hypothyroidism without goitre
0.000 0.799 0.201
E73.9 Lactose intolerance, unspecified
0.000 0.800 0.200
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.802 0.198
L70 Acne
0.000 0.803 0.197
E58 Dietary calcium deficiency
0.000 0.804 0.196
E51.2 Wernicke's encephalopathy
0.000 0.804 0.195
L71.1 Rhinophyma
0.000 0.806 0.194
E03.8 Other specified hypothyroidism
0.000 0.808 0.192
E11.4 With neurological complications
0.000 0.809 0.191
E66 Obesity
0.000 0.809 0.191
L71.8 Other rosacea
0.000 0.810 0.190
L71.0 Perioral dermatitis
0.000 0.810 0.190
E83.9 Disorder of mineral metabolism, unspecified
0.052 0.814 0.134
E83.8 Other disorders of mineral metabolism
0.052 0.814 0.134
E83.2 Disorders of zinc metabolism
0.052 0.814 0.134
E83.0 Disorders of copper metabolism
0.052 0.814 0.134

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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