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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs206785
log Bayes Factor = 84.9346
Chromosome 6   position 32,934,441  (GRCh37) Explore rs206785 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
E10.4 With neurological complications
0.000 0.003 0.997
E16.2 Hypoglycaemia, unspecified
0.000 0.004 0.996
L40.9 Psoriasis, unspecified
0.996 0.004 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.005 0.995
E00-E07 Disorders of thyroid gland
0.000 0.006 0.994
L40 Psoriasis
0.994 0.006 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.008 0.992
L40.5 Arthropathic psoriasis
0.992 0.008 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.010 0.990
E40-E46 Malnutrition
0.000 0.028 0.972
E46 Unspecified protein-energy malnutrition
0.000 0.047 0.953
E10.2 With renal complications
0.000 0.051 0.949
L40.8 Other psoriasis
0.939 0.061 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.103 0.897
K90 Intestinal malabsorption
0.000 0.146 0.854
E10.8 With unspecified complications
0.000 0.149 0.851
E10.5 With peripheral circulatory complications
0.000 0.158 0.842
E13 Other specified diabetes mellitus
0.000 0.162 0.838
K90.9 Intestinal malabsorption, unspecified
0.000 0.178 0.822
E07 Other disorders of thyroid
0.000 0.214 0.786
E16.1 Other hypoglycaemia
0.000 0.241 0.759
E13.9 Without complications
0.000 0.261 0.739
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.285 0.715
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.285 0.715
E16.4 Abnormal secretion of gastrin
0.000 0.285 0.715
E16.3 Increased secretion of glucagon
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.286 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.286 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.286 0.714
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.287 0.713
E00 Congenital iodine-deficiency syndrome
0.000 0.287 0.713
L40.4 Guttate psoriasis
0.712 0.288 0.000
L40.2 Acrodermatitis continua
0.712 0.288 0.000
L40.3 Pustulosis palmaris et plantaris
0.709 0.291 0.000
E10.7 With multiple complications
0.000 0.292 0.707
E05.8 Other thyrotoxicosis
0.000 0.296 0.704
E07.9 Disorder of thyroid, unspecified
0.000 0.298 0.702
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.303 0.697
E45 Retarded development following protein-energy malnutrition
0.000 0.303 0.697
E43 Unspecified severe protein-energy malnutrition
0.000 0.303 0.697
E42 Marasmic kwashiorkor
0.000 0.303 0.697
E41 Nutritional marasmus
0.000 0.303 0.697
E40 Kwashiorkor
0.000 0.303 0.697
E10.0 With coma
0.000 0.309 0.691
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.334 0.666
L40.1 Generalised pustular psoriasis
0.664 0.336 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.338 0.662
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.339 0.661
E10.6 With other specified complications
0.000 0.354 0.645
K90.3 Pancreatic steatorrhoea
0.000 0.387 0.613
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.387 0.613
K90.1 Tropical sprue
0.000 0.387 0.613
E14 Unspecified diabetes mellitus
0.000 0.396 0.604
E13.8 With unspecified complications
0.000 0.399 0.601
E13.7 With multiple complications
0.000 0.399 0.601
E13.6 With other specified complications
0.000 0.399 0.601
E13.5 With peripheral circulatory complications
0.000 0.399 0.601
E13.4 With neurological complications
0.000 0.399 0.601
E13.2 With renal complications
0.000 0.399 0.601
E13.1 With ketoacidosis
0.000 0.399 0.601
E13.0 With coma
0.000 0.399 0.601
K90.8 Other intestinal malabsorption
0.000 0.435 0.565
E07.1 Dyshormogenetic goitre
0.000 0.437 0.563
E07.0 Hypersecretion of calcitonin
0.000 0.437 0.563
E13.3 With ophthalmic complications
0.000 0.437 0.563
E65-E68 Obesity and other hyperalimentation
0.000 0.438 0.562
E14.3 With ophthalmic complications
0.000 0.477 0.523
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.489 0.511
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.489 0.511
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.489 0.511
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.489 0.511
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.489 0.511
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.489 0.511
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.489 0.511
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.489 0.511
E44.1 Mild protein-energy malnutrition
0.000 0.500 0.500
E44.0 Moderate protein-energy malnutrition
0.000 0.500 0.500
E06 Thyroiditis
0.000 0.507 0.493
L40.0 Psoriasis vulgaris
0.471 0.528 0.000
E14.8 With unspecified complications
0.000 0.530 0.470
E65 Localised adiposity
0.000 0.538 0.462
E14.6 With other specified complications
0.000 0.551 0.449
E20-E35 Disorders of other endocrine glands
0.000 0.558 0.442
E14.4 With neurological complications
0.000 0.563 0.437
E14.7 With multiple complications
0.000 0.567 0.433
E14.0 With coma
0.000 0.567 0.433
E14.2 Withrenal complications
0.000 0.572 0.428
E67 Other hyperalimentation
0.000 0.597 0.403
E68 Sequelae of hyperalimentation
0.000 0.597 0.403
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.599 0.401
E14.5 With peripheral circulatory complications
0.000 0.602 0.398
E07.8 Other specified disorders of thyroid
0.000 0.614 0.385
E50-E64 Other nutritional deficiencies
0.000 0.615 0.385
E22 Hyperfunction of pituitary gland
0.000 0.625 0.375
E27 Other disorders of adrenal gland
0.000 0.629 0.371
E14.1 With ketoacidosis
0.000 0.630 0.370
E26 Hyperaldosteronism
0.000 0.637 0.363
E06.4 Drug-induced thyroiditis
0.000 0.646 0.353
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.646 0.353
E06.0 Acute thyroiditis
0.000 0.646 0.353
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.648 0.352
E06.1 Subacute thyroiditis
0.000 0.649 0.351
E06.3 Autoimmune thyroiditis
0.000 0.654 0.346
E22.1 Hyperprolactinaemia
0.000 0.673 0.327
E25 Adrenogenital disorders
0.000 0.676 0.324
E58 Dietary calcium deficiency
0.000 0.676 0.324
L40-L45 Papulosquamous disorders
0.324 0.676 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.678 0.322
E27.1 Primary adrenocortical insufficiency
0.000 0.681 0.319
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.683 0.317
E32 Diseases of thymus
0.000 0.683 0.317
E30 Disorders of puberty, not elsewhere classified
0.000 0.683 0.317
E06.5 Other chronic thyroiditis
0.000 0.687 0.312
E03 Other hypothyroidism
0.000 0.691 0.309
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.704 0.296
E26.0 Primary hyperaldosteronism
0.000 0.704 0.296
E34 Other endocrine disorders
0.000 0.706 0.294
E31 Polyglandular dysfunction
0.000 0.709 0.291
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.710 0.290
E67.8 Other specified hyperalimentation
0.000 0.711 0.289
E67.3 Hypervitaminosis D
0.000 0.711 0.289
E67.2 Megavitamin-B6 syndrome
0.000 0.711 0.289
E67.1 Hypercarotenaemia
0.000 0.711 0.289
E67.0 Hypervitaminosis A
0.000 0.711 0.289
E29 Testicular dysfunction
0.000 0.716 0.284
E24 Cushing's syndrome
0.000 0.721 0.278
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.723 0.276
E63 Other nutritional deficiencies
0.000 0.723 0.276
E50 Vitamin A deficiency
0.000 0.723 0.276
E60 Dietary zinc deficiency
0.000 0.723 0.276
E59 Dietary selenium deficiency
0.000 0.723 0.276
E54 Ascorbic acid deficiency
0.000 0.723 0.276
E52 Niacin deficiency [pellagra]
0.000 0.723 0.276
E26.9 Hyperaldosteronism, unspecified
0.000 0.724 0.276
E21.0 Primary hyperparathyroidism
0.000 0.724 0.276
E21.2 Other hyperparathyroidism
0.000 0.724 0.276
E27.9 Disorder of adrenal gland, unspecified
0.000 0.724 0.276
E56 Other vitamin deficiencies
0.000 0.730 0.270
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.731 0.269
E22.8 Other hyperfunction of pituitary gland
0.000 0.731 0.269
E27.5 Adrenomedullary hyperfunction
0.000 0.734 0.266
E27.0 Other adrenocortical overactivity
0.000 0.734 0.266
E26.8 Other hyperaldosteronism
0.000 0.740 0.260
E26.1 Secondary hyperaldosteronism
0.000 0.740 0.260
L42 Pityriasis rosea
0.258 0.742 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.746 0.254
E21.4 Other specified disorders of parathyroid gland
0.000 0.748 0.252
E27.2 Addisonian crisis
0.000 0.754 0.246
E34.8 Other specified endocrine disorders
0.000 0.754 0.245
E51 Thiamine deficiency
0.000 0.756 0.243
E22.0 Acromegaly and pituitary gigantism
0.000 0.758 0.242
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.761 0.239
E03.8 Other specified hypothyroidism
0.000 0.763 0.237
E06.9 Thyroiditis, unspecified
0.000 0.766 0.233
E25.9 Adrenogenital disorder, unspecified
0.000 0.767 0.232
E25.8 Other adrenogenital disorders
0.000 0.767 0.232
L44 Other papulosquamous disorders
0.232 0.768 0.000
L41 Parapsoriasis
0.232 0.768 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.232 0.768 0.000
E20 Hypoparathyroidism
0.000 0.770 0.230
E30.9 Disorder of puberty, unspecified
0.000 0.772 0.228
E30.8 Other disorders of puberty
0.000 0.772 0.228
E30.1 Precocious puberty
0.000 0.772 0.228
E30.0 Delayed puberty
0.000 0.772 0.228
E32.9 Disease of thymus, unspecified
0.000 0.772 0.228
E32.8 Other diseases of thymus
0.000 0.772 0.228
E32.1 Abscess of thymus
0.000 0.772 0.228
E32.0 Persistent hyperplasia of thymus
0.000 0.772 0.228
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.772 0.228
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.772 0.228
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.772 0.228
E03.5 Myxoedema coma
0.000 0.778 0.222
E03.4 Atrophy of thyroid (acquired)
0.000 0.778 0.222
E03.3 Postinfectious hypothyroidism
0.000 0.778 0.222
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.781 0.218
E61 Deficiency of other nutrient elements
0.000 0.783 0.217
E55 Vitamin D deficiency
0.000 0.784 0.216
E21.3 Hyperparathyroidism, unspecified
0.000 0.789 0.211
E34.5 Androgen resistance syndrome
0.000 0.789 0.211
E34.4 Constitutional tall stature
0.000 0.789 0.211
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.789 0.211
E34.1 Other hypersecretion of intestinal hormones
0.000 0.789 0.211
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.789 0.211
E34.0 Carcinoid syndrome
0.000 0.790 0.210
E31.9 Polyglandular dysfunction, unspecified
0.000 0.791 0.209
E31.8 Other polyglandular dysfunction
0.000 0.791 0.209
E31.1 Polyglandular hyperfunction
0.000 0.791 0.209
E24.8 Other Cushing's syndrome
0.000 0.792 0.208
E03.1 Congenital hypothyroidism without goitre
0.000 0.794 0.206
E29.9 Testicular dysfunction, unspecified
0.000 0.796 0.203
E29.8 Other testicular dysfunction
0.000 0.796 0.203
E29.0 Testicular hyperfunction
0.000 0.796 0.203
E24.0 Pituitary-dependent Cushing's disease
0.000 0.797 0.203
E24.2 Drug-induced Cushing's syndrome
0.000 0.800 0.200
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.800 0.200
E24.3 Ectopic ACTH syndrome
0.000 0.800 0.200
E24.1 Nelson's syndrome
0.000 0.800 0.200
E50.9 Vitamin A deficiency, unspecified
0.000 0.801 0.198
E50.8 Other manifestations of vitamin A deficiency
0.000 0.801 0.198
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.801 0.198
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.801 0.198
E50.5 Vitamin A deficiency with night blindness
0.000 0.801 0.198
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.801 0.198
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.801 0.198
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.801 0.198
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.801 0.198
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.801 0.198
E63.9 Nutritional deficiency, unspecified
0.000 0.801 0.198
E63.8 Other specified nutritional deficiencies
0.000 0.801 0.198
E63.1 Imbalance of constituents of food intake
0.000 0.801 0.198
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.801 0.198
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.801 0.198
E64.8 Sequelae of other nutritional deficiencies
0.000 0.801 0.198
E64.3 Sequelae of rickets
0.000 0.801 0.198
E64.2 Sequelae of vitamin C deficiency
0.000 0.801 0.198
E64.1 Sequelae of vitamin A deficiency
0.000 0.801 0.198
E64.0 Sequelae of protein-energy malnutrition
0.000 0.801 0.198
E34.3 Short stature, not elsewhere classified
0.000 0.806 0.194
E56.9 Vitamin deficiency, unspecified
0.000 0.806 0.194
E56.8 Deficiency of other vitamins
0.000 0.806 0.194
E56.0 Deficiency of vitamin E
0.000 0.806 0.194
E27.8 Other specified disorders of adrenal gland
0.000 0.807 0.193
E56.1 Deficiency of vitamin K
0.000 0.813 0.187
C91.1 Chronic lymphocytic leukaemia
0.000 0.816 0.184
E31.0 Autoimmune polyglandular failure
0.000 0.817 0.182
E51.9 Thiamine deficiency, unspecified
0.000 0.825 0.175
E51.8 Other manifestations of thiamine deficiency
0.000 0.825 0.175
E51.1 Beriberi
0.000 0.825 0.175
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.828 0.172
E29.1 Testicular hypofunction
0.000 0.830 0.170
L41.9 Parapsoriasis, unspecified
0.167 0.833 0.000
L41.8 Other parapsoriasis
0.167 0.833 0.000
L41.5 Retiform parapsoriasis
0.167 0.833 0.000
L41.4 Large plaque parapsoriasis
0.167 0.833 0.000
L41.3 Small plaque parapsoriasis
0.167 0.833 0.000
L41.2 Lymphomatoid papulosis
0.167 0.833 0.000
L41.1 Pityriasis lichenoides chronica
0.167 0.833 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.167 0.833 0.000
L44.9 Papulosquamous disorder, unspecified
0.167 0.833 0.000
L44.8 Other specified papulosquamous disorders
0.167 0.833 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.167 0.833 0.000
L44.3 Lichen ruber moniliformis
0.167 0.833 0.000
L44.2 Lichen striatus
0.167 0.833 0.000
L44.1 Lichen nitidus
0.167 0.833 0.000
L44.0 Pityriasis rubra pilaris
0.167 0.833 0.000
E20.1 Pseudohypoparathyroidism
0.000 0.835 0.165
E20.0 Idiopathic hypoparathyroidism
0.000 0.835 0.165
E28 Ovarian dysfunction
0.001 0.837 0.162
E61.9 Deficiency of nutrient element, unspecified
0.000 0.844 0.155
E61.8 Deficiency of other specified nutrient elements
0.000 0.844 0.155
E61.7 Deficiency of multiple nutrient elements
0.000 0.844 0.155
E61.6 Vanadium deficiency
0.000 0.844 0.155
E61.5 Molybdenum deficiency
0.000 0.844 0.155
E61.4 Chromium deficiency
0.000 0.844 0.155
E61.3 Manganese deficiency
0.000 0.844 0.155
E61.0 Copper deficiency
0.000 0.844 0.155
E55.0 Rickets, active
0.000 0.845 0.155
E53 Deficiency of other B group vitamins
0.000 0.849 0.151
E20.8 Other hypoparathyroidism
0.000 0.851 0.149
E34.9 Endocrine disorder, unspecified
0.000 0.857 0.142
E51.2 Wernicke's encephalopathy
0.001 0.858 0.142
E24.9 Cushing's syndrome, unspecified
0.000 0.859 0.141
E61.2 Magnesium deficiency
0.000 0.865 0.134
L43 Lichen planus
0.134 0.866 0.000
E61.1 Iron deficiency
0.000 0.874 0.126
E28.9 Ovarian dysfunction, unspecified
0.001 0.883 0.116
E28.8 Other ovarian dysfunction
0.001 0.883 0.116
E28.1 Androgen excess
0.001 0.883 0.116
E28.0 Oestrogen excess
0.001 0.883 0.116
E23 Hypofunction and other disorders of pituitary gland
0.000 0.885 0.115
E53.1 Pyridoxine deficiency
0.000 0.891 0.108
E53.0 Riboflavin deficiency
0.000 0.891 0.108
E20.9 Hypoparathyroidism, unspecified
0.001 0.892 0.107
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.105 0.895 0.000
E14.9 Without complications
0.000 0.895 0.105
E04 Other non-toxic goitre
0.000 0.896 0.104
E53.9 Vitamin B deficiency, unspecified
0.000 0.899 0.100
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.100 0.900 0.000
T39.1 4-Aminophenol derivatives
0.099 0.901 0.000
L43.3 Subacute (active) lichen planus
0.096 0.904 0.000
L43.2 Lichenoid drug reaction
0.096 0.904 0.000
L43.1 Bullous lichen planus
0.096 0.904 0.000
L43.0 Hypertrophic lichen planus
0.096 0.904 0.000
E28.3 Primary ovarian failure
0.001 0.905 0.094
E55.9 Vitamin D deficiency, unspecified
0.000 0.905 0.095
L43.8 Other lichen planus
0.088 0.911 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.917 0.082
E23.1 Drug-induced hypopituitarism
0.000 0.917 0.082
R06.8 Other and unspecified abnormalities of breathing
0.082 0.918 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.919 0.081
T39.0 Salicylates
0.077 0.923 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.076 0.924 0.000
E04.8 Other specified non-toxic goitre
0.000 0.925 0.075
T39.4 Antirheumatics, not elsewhere classified
0.072 0.928 0.000
T39.2 Pyrazolone derivatives
0.072 0.928 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.067 0.933 0.000
E66 Obesity
0.000 0.936 0.064
E04.9 Non-toxic goitre, unspecified
0.000 0.937 0.063
E23.2 Diabetes insipidus
0.000 0.938 0.062
E23.6 Other disorders of pituitary gland
0.000 0.943 0.056
C91 Lymphoid leukaemia
0.000 0.944 0.056
K90-K93 Other diseases of the digestive system
0.000 0.945 0.055
T36-T50 Poisoning by drugs, medicaments and biological substances
0.052 0.948 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.052 0.948 0.000
H36.0 Diabetic retinopathy
0.000 0.951 0.049
T43.3 Phenothiazine antipsychotics and neuroleptics
0.049 0.951 0.000
T43.2 Other and unspecified antidepressants
0.048 0.952 0.000
E66.1 Drug-induced obesity
0.000 0.954 0.046
C91.0 Acute lymphoblastic leukaemia
0.000 0.955 0.045
T43.5 Other and unspecified antipsychotics and neuroleptics
0.044 0.956 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.043 0.957 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.959 0.041
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.959 0.041
C91.7 Other lymphoid leukaemia
0.000 0.959 0.041
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.959 0.041
C91.3 Prolymphocytic leukaemia
0.000 0.959 0.041
C91.2 Subacute lymphocytic leukaemia
0.000 0.959 0.041
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.040 0.960 0.000
E66.0 Obesity due to excess calories
0.000 0.960 0.040
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.040 0.960 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.040 0.960 0.000
T36 Poisoning by systemic antibiotics
0.040 0.960 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.960 0.040
T43.4 Butyrophenone and thioxanthene neuroleptics
0.039 0.961 0.000
C91.5 Adult T-cell leukaemia
0.000 0.961 0.039
C91.9 Lymphoid leukaemia, unspecified
0.000 0.961 0.039
T43.6 Psychostimulants with abuse potential
0.038 0.962 0.000
E11.5 With peripheral circulatory complications
0.000 0.962 0.038
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.038 0.962 0.000
E23.0 Hypopituitarism
0.000 0.962 0.038
T41 Poisoning by anaesthetics and therapeutic gases
0.038 0.962 0.000
T43.9 Psychotropic drug, unspecified
0.037 0.963 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.037 0.963 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.037 0.963 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.964 0.036
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.034 0.966 0.000
T42.1 Iminostilbenes
0.034 0.966 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.034 0.966 0.000
T47.2 Stimulant laxatives
0.033 0.967 0.000
T42.4 Benzodiazepines
0.033 0.967 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.968 0.032
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.032 0.968 0.000
T38.1 Thyroid hormones and substitutes
0.032 0.968 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.032 0.968 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.032 0.968 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.031 0.969 0.000
E04.0 Non-toxic diffuse goitre
0.001 0.969 0.030
T42.5 Mixed antiepileptics, not elsewhere classified
0.031 0.969 0.000
T42.2 Succinimides and oxazolidinediones
0.031 0.969 0.000
T42.0 Hydantoin derivatives
0.030 0.970 0.000
T36.3 Macrolides
0.030 0.970 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.030 0.970 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.030 0.970 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.970 0.030
E11.7 With multiple complications
0.000 0.970 0.029
T36.0 Penicillins
0.029 0.970 0.000
T47.0 Histamine H(2)-receptor antagonists
0.029 0.971 0.000
T47.4 Other laxatives
0.029 0.971 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.029 0.971 0.000
T37.5 Antiviral drugs
0.029 0.971 0.000
T37.4 Anthelminthics
0.029 0.971 0.000
T37.3 Other antiprotozoal drugs
0.029 0.971 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.029 0.971 0.000
T37.1 Antimycobacterial drugs
0.029 0.971 0.000
T37.0 Sulphonamides
0.029 0.971 0.000
T38.9 Other and unspecified hormone antagonists
0.029 0.971 0.000
T38.7 Androgens and anabolic congeners
0.029 0.971 0.000
T38.5 Other oestrogens and progestogens
0.029 0.971 0.000
T38.4 Oral contraceptives
0.029 0.971 0.000
T38.2 Antithyroid drugs
0.029 0.971 0.000
T38.0 Glucocorticoids and synthetic analogues
0.029 0.971 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.029 0.971 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.029 0.971 0.000
T47.7 Emetics
0.029 0.971 0.000
T47.6 Antidiarrhoeal drugs
0.029 0.971 0.000
T47.5 Digestants
0.029 0.971 0.000
T47.3 Saline and osmotic laxatives
0.029 0.971 0.000
T36.9 Systemic antibiotic, unspecified
0.029 0.971 0.000
T36.8 Other systemic antibiotics
0.029 0.971 0.000
T36.7 Antifungal antibiotics, systemically used
0.029 0.971 0.000
T36.6 Rifamycins
0.029 0.971 0.000
T36.5 Aminoglycosides
0.029 0.971 0.000
T36.4 Tetracyclines
0.029 0.971 0.000
T36.2 Chloramphenicol group
0.029 0.971 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.029 0.971 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.971 0.029
K93.1 Megacolon in Chagas' disease
0.000 0.971 0.029
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.971 0.029
T42.3 Barbiturates
0.028 0.972 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.028 0.972 0.000
T49.9 Topical agent, unspecified
0.027 0.972 0.000
T49.8 Other topical agents
0.027 0.972 0.000
T49.7 Dental drugs, topically applied
0.027 0.972 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.027 0.972 0.000
T49.5 Ophthalmological drugs and preparations
0.027 0.972 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.027 0.972 0.000
T49.3 Emollients, demulcents and protectants
0.027 0.972 0.000
T49.2 Local astringents and local detergents
0.027 0.972 0.000
T49.1 Antipruritics
0.027 0.972 0.000
E28.2 Polycystic ovarian syndrome
0.002 0.972 0.026
T41.5 Therapeutic gases
0.027 0.973 0.000
T41.4 Anaesthetic, unspecified
0.027 0.973 0.000
T41.3 Local anaesthetics
0.027 0.973 0.000
T41.2 Other and unspecified general anaesthetics
0.027 0.973 0.000
T41.1 Intravenous anaesthetics
0.027 0.973 0.000
T41.0 Inhaled anaesthetics
0.027 0.973 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.027 0.973 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.027 0.973 0.000
R06 Abnormalities of breathing
0.027 0.973 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.026 0.974 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.026 0.974 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.025 0.975 0.000
T48.5 Anti-common-cold drugs
0.025 0.975 0.000
T48.4 Expectorants
0.025 0.975 0.000
T48.3 Antitussives
0.025 0.975 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.025 0.975 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.025 0.975 0.000
T48.0 Oxytocic drugs
0.025 0.975 0.000
E11.8 With unspecified complications
0.000 0.975 0.024
R06.1 Stridor
0.025 0.975 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.024 0.976 0.000
E11.2 With renal complications
0.000 0.976 0.024
T50.1 Loop [high-ceiling] diuretics
0.024 0.976 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.024 0.976 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.023 0.977 0.000
T45.8 Other primarily systemic and haematological agents
0.023 0.977 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.023 0.977 0.000
T45.6 Fibrinolysis-affecting drugs
0.023 0.977 0.000
T45.4 Iron and its compounds
0.023 0.977 0.000
T45.3 Enzymes, not elsewhere classified
0.023 0.977 0.000
R06.5 Mouth breathing
0.023 0.977 0.000
E11.6 With other specified complications
0.000 0.977 0.023
C91.4 Hairy-cell leukaemia
0.000 0.977 0.023
T45.5 Anticoagulants
0.023 0.977 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.023 0.977 0.000
T50.8 Diagnostic agents
0.022 0.977 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.022 0.978 0.000
T45.0 Antiallergic and antiemetic drugs
0.022 0.978 0.000
E11.0 With coma
0.000 0.978 0.021
T50.7 Analeptics and opioid receptor antagonists
0.021 0.978 0.000
T50.5 Appetite depressants
0.021 0.978 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.021 0.978 0.000
T50.0 Mineralocorticoids and their antagonists
0.021 0.978 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.021 0.978 0.000
R06.4 Hyperventilation
0.021 0.979 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.979 0.021
T50.4 Drugs affecting uric acid metabolism
0.021 0.979 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.020 0.979 0.000
L43.9 Lichen planus, unspecified
0.020 0.980 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.020 0.980 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.020 0.980 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.020 0.980 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.020 0.980 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.020 0.980 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.020 0.980 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.020 0.980 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.020 0.980 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.020 0.980 0.000
T44.0 Anticholinesterase agents
0.020 0.980 0.000
R06.7 Sneezing
0.020 0.980 0.000
R06.3 Periodic breathing
0.020 0.980 0.000
S82.00 Fracture of patella (closed)
0.000 0.980 0.020
T45.2 Vitamins, not elsewhere classified
0.019 0.980 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.019 0.981 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.019 0.981 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.019 0.981 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.019 0.981 0.000
T46.7 Peripheral vasodilators
0.019 0.981 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.019 0.981 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.018 0.982 0.000
M07.3 Other psoriatic arthropathies
0.018 0.982 0.000
E11.1 With ketoacidosis
0.000 0.982 0.018
T40.1 Heroin
0.017 0.983 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.017 0.983 0.000
T40.6 Other and unspecified narcotics
0.016 0.983 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.016 0.983 0.000
T40.8 Lysergide [LSD]
0.016 0.983 0.000
T40.7 Cannabis (derivatives)
0.016 0.983 0.000
T40.3 Methadone
0.016 0.983 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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